the organization of the nervous system
DESCRIPTION
The organization of the nervous system. Structure of the human cerebral cortex. Structure of the human cerebral cortex. Sensory map. Structure of the human cerebral cortex. Motor map. Neuromuscular junction. Neuromuscular junction. How to manipulate it ?. Curare. ACh-ase inhibitors . - PowerPoint PPT PresentationTRANSCRIPT
The organization of the nervous system
Structure of the human cerebral cortex
Structure of the human cerebral cortex
Sensory map
Structure of the human cerebral cortexMotor map
Neuromuscular junction
Neuromuscular junction
How to manipulate it ?CurareACh-ase inhibitors Myastenia gravisBotulinum toxinPesticides
Parkinson’s diseaseBasal ganglia
Parkinson’s diseaseMost common symptoms
Shaking (tremor) at Rest
Stiffness (rigidity)
Slow Movement (bradykinesia)Balance Problems (postural instability)
Multiple sclerosis
Myelin
Multiple sclerosis
Demyelination
Multiple sclerosisProgression
AMLAmyotrophic Lateral Sclerosis
(Lou Gherig disease”)
Mutation or defect in neuronal SOD activity
Excess oxidative stress to neuronal mitochondria
Degeneration of motor neurons
Paralysis – muscular atrophy
Exacerbated by glutamate neurotransmitter activity