Sensor100 March 2015 1

Sensor100The International Bio-sensor and Chemo-sensor Network

March 2015

© 2015 Captum Capital Limited

Sensors in Medicine 2015 Reception

Sensor100 March 2015 2

From the Editor 3

SiM15 Poster Competition and Panel Discussion 4

Coming Events 7

4th Internl Conference on Biosensing Technology 8

7th Annual Bioanalytical Sensing Tech. Conference 9

ON Helix 10

IEEE Sensors 2015 11

Company News 12

Technology News 18

About Sensor100 25

Cover Image: Sensors in Medicine 2015 Reception in partial silhouette

www.sensor100.com

Contents

3 Sensor100 March 2015

People who attend conferences, as opposed to organising them, pos-sibly have little appreciation how much work is involved, both before and after the event.

Now Sensors in Medicine is over for another year, we are in the middle now of cleaning up after us. This mostly involves a seemingly endless series of emails: I need an attendance certificate (on its way); can you confirm my slides were deleted from the PC? (yes, done); can you repeat the Workshop in Germany? (maybe later); it wasn’t what I expected, can I get my money back? (um...no); where will it be next year? (don’t know yet, we’ll email you). And so on.

Having given you a flavor of the post-conference process, not to men-tion thanking everybody who took part, you may have an appreciation as to why this Newsletter is a bit shorter than usual.

Kind regards

Michaelmichael@sensor100.com

From the editor...

Sensor100 March 2015 4

Luca Marmugi, Dr. Mike Bond, Dr. Karen Law, Jules Hammond, Niamh Brannelly, Sammer-ul Hassan (insert)

The winners of the MRC Technology sponsored Poster Competition at Sensors in Medicine 2015 were:First Place: All optical atomic magnetometer for heart magnetic induction tomography - Luca Marmugi (UCL)Runners up: Impedimetric assessment of polyaniline modified silver electrodes for blood ammonia sensing - Niamh Brannelly (UWE)Nanogap generator-collector devices with miniaturised electronics for analytical applications - Jules Hammond (University of Bath)A droplet based portable continuous chemical sampling and monitor-ing device - Sammer-ul Hassan (University of Southampton)

The Awards were presented by Dr. Karen Law and Dr. Mike Bond of MRC Technology

Sensors in Medicine 2015 Poster Competition

5 Sensor100 March 2015

Panel Discussions have become a feature of Sensor100 Conferences, and although they rarely solve the topic problem, they do lead to lively debate.

At Sensors in Medicine 2015, we discussed the classic problem of:“Technology Push vs. Clinical Pull”

Danny Green (Yaqrit and Imperial College) took a balanced view, that both were necessary, with the addition of finance to grease the wheels. Tony Killard (UWE) argued for technology push as an inevi-table consequence of academic research. Jeremy Huddy (NIHR DEC London) defended the NHS in applying research to solve clinical needs. Walter De Raedt (imec) also suggested that innovation hap-pened when technology and need came together. Dr. Michael Brand (Captum) gave some examples of healthcare applications of sen-sors where both drivers operated. All in, a useful albeit inconclusive debate.[ A full report on Sensors in Medicine 2015 will be in the April issue of Sensor100 ]

Sensors in Medicine 2015 Panel Discussion

Danny Green, Prof. Tony Killard, Dr. Michael Brand, Jeremy Huddy MRCS, Walter De Raedt

Sensor100 March 2015 6

P H O T O N I S O U R B U S I N E S S

Next Generation Ultra-Compact �PMT Assembly

Introducing the world’s most compact and light-weight PMT assembly incorporating the first ever MEMS (Micro-Electro-Mechanical Systems) based photomultiplier tube. This unique technology will allow for the development of increasingly miniaturised equipment.

Features:

� Ultra-compact and light-weight� High sensitivity bialkali photocathode� High gain: 2 x 10 6

� Developed for mass-production

Compact, high sensitivity photometric systems including:

� Portable medical devices� Portable environmental measurement devices � Medical monitors

www.hamamatsu.com

7 Sensor100 March 2015

Coming Events

Medical MEMS and Sensors 2015April 29 -30 Santa Clara CA USA

Biomarkers and Diagnostics World Congress 2015May 5-7 Philadelphia PA USA

30th Anniversary Sensors Expo and ConferenceJune 9-11 Long Beach CA USA

11th Annual COMSOL European Conference October 14 - 16 Grenoble FR

List your event on Sensor100’s Events CalendarSend details to info@sensor100.com

Sensor100 March 2015 8

10 Reasons to Attend the 4th International Conference on Bio-Sensing Technology

1. Present your latest research

2. Learn from internationally renowned researchers including these invited speakers3. Understand the current state of research and the challenges to future discovery

4. Meet with international colleagues, make new friends

5. Visit the exhibition of leading-edge, commercial technology

6. Grow your LinkedIn connections

7. Present your poster to the world with the new (free) Poster in my Pocket app8. Socialise with fellow scientists at the Conference Dinner

9. Meet the Editors of Biosensors & Bioelectronics and the new Open Access journal Sensing andBio-Sensing Research

10. Explore the vibrant city of Lisbon in your free time!

Themes1. Novel biomarkers

2. Biosensor surfaces

3. Novel detection technologies

4. Instrumentation and Integration

5. Commercialisation and impact

Conference Chairman

Professor Richard Luxton,

Institute of Bio-Sensing Technology, UWE Bristol, UK

Visit: WWW.BIOSENSINGCONFERENCE.COM

9 Sensor100 March 2015

Bioanalytical Sensing Technologies Conference

Tuesday 16th June 2015The Royal Society of Chemistry,

Burlington House, Piccadilly, London

This is the seventh annual AAMG Conference concerning monitoring and analysis using sensor technologies. The conference will examine the design and application of materials and development of sensors for monitoring medical and biological processes. Sessions will feature invited presentations by experts on a variety of topics in the following areas: New materials in sensor technologies and monitoring systems.

Sensors and materials for medical and biochemical monitoring.

Instrumentation.

Informatics in sensing applications; data acquisition, transmis-sion, validation and interpretation of results (bio-informatics).

The conference will be supplemented with poster presentations and exhibition.

Poster Abstract submission deadline: 30th April

Please visit the website for full conference details, poster abstract submission and how to register at:

http://www.aamg-rsc.org

Sensor100 March 2015 10

11 Sensor100 March 2015

FIRST CALL FOR PAPERS

SENSORS 2015IEEE

November 1-4, 2015BEXCO

Busan, Korea������

Conference Website - http://ieee-sensors2015.org/

Abstract Submission Deadline April 17, 2015

Proposals for Organized Sessions April 17, 2015

Proposals for Tutorials, Workshops May 18, 2015

Notification of Paper Acceptance July 1, 2015

Submission of Final Papers September 1,2015

Conference Email laurenp@conferencecatalysts.com

IMPORTANT DATES

Co-General Chairs:

Chris Schober, USA

Kukjin Chun, Korea

Technical Program Co-Chairs:Seong Ho Kong, KoreaSuntae Jung, KoreaLocal Arrangements Chair:Wan-Young Chung, KoreaTreasurer:Edward Grant, USAPublicity Co-Chairs:Edward Grant, USAJunghoon Lee, KoreaExhibits Co-Chairs:Srinivas Tadigadapa, USAChong-Yun Kang, Korea PCO:Conference Catalysts, USAPaper Submission Service:Epapers

The IEEE SENSORS Conference is a forum for presentation, discussion,and exchange of state-of-the art information including the latestresearch and development in sensors and their related fields. It bringstogether researchers, developers, and practitioners from diversefields including international scientists and engineers from academia,research institutes, and companies to present and discuss the latestresults in the general field of sensors.

Busan Attractions: Busan is Korea's second largest city. Tourists oftencome to this region to hike and to visit the Buddhist Temples locateddeep within the region's mountains. The Beomeosa Temple, foundedin 678 AD, is perhaps one of the most frequented temples in the areaand is always packed with worshipers and tourists. For art buffs,Busan offers several museums and historical buildings. If scenery isyour thing, try visiting the Dongbaek Island, or bird watch at theNakdong river estuary.

Sensor100 March 2015 12

Company News

Apple Launches ResearchKitApple has released ResearchKit, an open source software framework that makes it easy for researchers and developers to create apps that could revolutionize medical studies, potentially trans-forming medicine forever. - so claims the company. No longer will clinical trial participants need to be near major medical hubs, nor will physicians need to wait for days or weeks for patient-submitted information. Instead, patients will be able to use iPhone apps built on top of ResearchKit, which can leverage both the device’s hardware (sensors, accelerometers, etc) and software (HealthKit, plus a new e-consent functionality that should clear most IRB barriers).

“We’ve been sending out questionaires to breast cancer survivors each quarter, asking them to remember how they felt weeks earlier,” explains Ann Partridge, director of the Dana Farber Cancer Institute’s Adult Survivorship Program, which helped create one of ResearchKit’s inaugural five apps. “It obviously can be difficult for people to remem-ber accurately, but now this app will let people provide us information in real-time. We think it will greatly improve the quality and quantity of our data.”

Here is how tech blogger David Pogue summed it up: “New apps for Parkinson’s, diabetes, asthma, heart health, breast cancer–this could be HUGE. No evident profit motive–Apple at its best.” — David Pogue (@Pogue) March 9, 2015

But, Fortune points out that only 14.8% of global smartphone us-ers currently run iOS, which is the only operating system on which ResearchKit apps can be built - over 80% of global smartphone users run Android, and won’t be able to take part in the clinical trials. An opportunity for Apple and Google to collaborate.

Reported by Fortune, 10 March

13 Sensor100 March 2015

Company News

Universal Biosensors Will Receive Additional Payment from SiemensUniversal Biosensors is poised to receive additional payments from Siemens (XETRA:SIE) to incorporate certain additional features that are expected to have high commercial value for its point-of-care

coagulation testing system. Both companies are now targeting the second half of 2016 for regulatory approval and commercial launch of these additional tests by Siemens. These could deliver new revenue streams and further accelerate growth for UBI. The Xprecia Stride Coagulation Analyzer was the first point-of-care coagulation testing system developed with Siemens, and was launched in December 2014.Read more...

Technology Poised to Replace Time-Consuming Tests Enable Point-of-Care ResultsPharmaco-Kinesis Corporation (PKC) and the Ohio Clinical Trials Collaborative (OCTC) announced that they have agreed to explore the potential of a partnership aimed at the development of technol-ogy that provides physicians real-time patient information that once required days to secure.

PKC hopes to engage the Ohio collaborative in testing and research related to the company’s SMART (Simultaneous Multiplexed Automat-ed Real Time Telemedicine) platform. The platform, which involves the use of biosensors linked to the cloud, could allow doctors to collect data about their patients’ conditions in the moment, rather than wait for the completion of laboratory testing and subsequent release of results.

Reported by BusinessWire March 9

Sensor100 March 2015 14

Amadeus’ Capital Partners Attends Mobile World Congress 2015

During the Congress Amadeus hosted the eleventh Amadeus Wireless Dinner, described by the local press as “El cla-sico” (a term normally used in Barcelona to describe the Barcelona – Real Madrid football match).Amadeus’ take on the important themes:

• The continually changing role of the mobile operator • Internet of Things – IoT • The 5G/Connected Car • “Network Softwarization” • Chinese Hardware Differentiation

Read more...

Vantage mHealthcare Im-proves Design and Technol-ogy of its SensorVantage mHealthcare Inc., expects to deliver 100 Health Sensors over the next month to hospitals and research facilities in the United States and New Zealand, advancing to the next phase of its research and development process, in order to prepare for hu-man clinical trials. Vantage is developing is developing point-of-care screening using Apps based upon chemical sensing residing within a small Bluetooth device that works with any smartphone, tablet or laptop.

Reported by BusinessWire March 9

Company News

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Company News

Developing Wireless Sensors for Treatment of Obesity and Diabetes Mayo Clinic and Gentag, Inc. have reached an agreement to develop the next generation of wearable biosensors designed to fight obesity and diabetes. A first-of-its-kind, the wearable patch sensors are the size of a small bandage, and are designed to be painless, wireless and disposable. In the bandage is a sensor that communicates via a closed-loop diabetes management system which is compatible with cell phones. The system will allow researchers to monitor movement and develop treatments for obesity and related conditions.

Read more...

Kongsberg acquires underwater chemical sensors specialist ControsKongsberg Maritime has acquired the remaining 90 per cent of the shares of the Germany based underwater chemical sensors specialist Contros Systems & Solutions GmbH. The company develops, pro-duces and markets underwater sensor systems to detect dissolved gasses such as hydrocarbons, CO2 and oxygen, as well as pH and total alkalinity (TA). Reported by Oil & Gas Technology

LamdaGen Corporation Launches Taiwan Diagnos-tic SubsidiaryLamdaGen Corporation, a nano-technology platform company that provides LSPR based plasmonic sensors and systems for In Vitro Di-agnostics (IVD), announced the opening of a wholly-owned subsidiary, LamdaGen Nanotechnology Taiwan Co., LTD. (LamdaGen Taiwan). By far the fastest growing IVD region in the world is Asia ($11.8 billion in 2014), and within that market Point of Care Testing (POCT) is greatly outperforming regional growth. Press Release March 18 2015

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Sphere Medical Launches Proxima in EuropeSphere Medical Holding plc announced the European launch of Proxima at the 35th International Sym-posium on Intensive Care and Emergency Medicine (ISICEM), Brussels, 17-20 March. Proxima is an in-line arterial blood gas analysis system. Read more...

Daktari Closes Funding Round for $15.5 MillionDaktari Diagnostics, which is commercializing a diagnostic platform to meet the need for accuracy, speed, and simplicity at the point of care,has closed a $15.5 million Series D round of funding from new and existing investors, led by Eastern Capital Limited and the Merck Glo-bal Health Innovation Fund. This investment marks the culmination of a 5 - year development program for Daktari’s platform, built oninnovative electrochemical and microfluidic technologies.

Electrochemical Sensing – Daktari CD4 takes advantage of lysate impedance spectroscopy.

Daktari_News_2015_2Mar

Company News

17 Sensor100 March 2015

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Sensor100 March 2015 18

Technology News

Draw Biosensors on Your SkinResearchers at the University of California, San Diego (UCSD) have developed special sensor-laden inks which could help diabetics monitor their blood sugar and allow people to stay on top of other elements of their body chemistry. The write-once, read-several-times inks could also let homeowners test for toxic pollutants, and help soldiers de-tect explosives and nerve agents on the battlefield.

IEEE Spectrum March 6

NIH Launches Competition For A Better Alcohol BiosensorA chunky bracelet or a fancy button-down shirt might be the next alcohol biosen-sor, if Kathy Jung has her way. Jung is a program director at the National Institute on Alcohol Abuse & Alcoholism (NIAAA), which has launched a $300,000 competi-tion to build a less obtrusive alcohol bio-sensor than ones currently available. Such a device could make alcohol research easier, assist alcohol abuse treatment profession-als, and improve monitoring for patients with medical conditions that are exacer-bated by alcohol.

Reported by C&EN March 23 2015

NIH is seeking wearable alcohol biosensors that are less obvious than the clunky black boxes used today.Credit: Alcohol Monitoring Systems, Inc.

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Technology News

Wearable sensors: enabling a $70bn wearable tech-nology market by 2025There will be over 3 billion sensors in wearable technology devices by 2025, with more than 30% being emerging sensor types. Wearable Sensors 2015-2025: Market Forecasts, Technologies, Players is a new IDTechEx report which provides the only up-to-date and specially tailored analysis of every prominent sensor type for wearable tech-nology. The report gives detailed coverage of the 15 most prominent sensor types in wearable technology today, including inertial measure-ment units (comprising combinations of accelerometers, gyroscopes, magnetometer and barometers), optical sensors (including optical heart rate monitoring, PPG and wearable cameras), wearable elec-trodes, chemical sensors, flexible stretch, pressure and impact sensors, temperature sensors, microphones and other emerging wearable sen-sors. Read more...

Frankie the dog ‘sniffs out thyroid cancer’A dog has been used to sniff out thyroid cancer in people who had not yet been diagnosed, US researchers say. Tests on 34 patients showed an 88% success rate in finding tumours. The team, present-ing their findings at the annual meeting of the Endocrine Society, said the animal had an “unbelievable” sense of smell. Cancer Research UK said using dogs would be impractical, but discovering the chemicals the dogs can smell could lead to new tests.

BBC News Health March 8, 2015

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Technology News

Write-On Biosensors Could Spell Easy Detection Nanoengineers lead by Prof. Joseph Wang at the University of California, San Diego have developed a bio-ink that reacts to chemicals and can be delivered with an ordinary ballpoint pen. The team said the ink can be used to draw on walls to detect pollution, or on smartphones to monitor vital signs. It might have military or industrial use, too – a line drawn on a wall could warn of explosives or hazardous chemicals in an area.Product Design & DevelopmentMarch 5 2015

Researchers have discovered an en-zymatic ink that can sense chemicals on walls, leaves, or skin.

Image credit: Jacobs School of Engi-neering/UC San Diego

Sensor100 March 2015 22

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