the bethesda system for reporting thyroid cytopathology mansour mehzad, md, fiac
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The Bethesda systemThe Bethesda system for reporting thyroidfor reporting thyroid
cytopathologycytopathology
Mansour Mehzad, MD, FIACMansour Mehzad, MD, FIAC
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The Bethesda system for reporting thyroid cytopathology I. Non-diagnostic or Unsatisfactory - Cyst fluid only ( macrophages only ) - Virtually acellular specimen - Other (obscuring blood, clotting artefact,etc)
II. Benign - Consistent with a benign follicular nodule ( includes adenomatous nodule,colloid nodule) - Consistent with lymphocytic (Hashimoto’s) thyroiditis in the proper clinical context - Consistent with granulomatous (subacute) thyroiditis - Other
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III. Atypia of undetermined significance or follicular lesion of undetermined significance
IV. Follicular neoplasm or suspicious for a follicular neoplasm - Specify if Hurthle cell (oncocytic) type
V. Suspicious for malignancy - Suspicious for papillary carcinoma - Suspicious for medullary carcinoma - Suspicious for metastatic carcinoma - Suspicious for lymphoma - Other
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VI. Malignant - Papillary carcinoma - Poorly differentiated carcinoma - Medullary thyroid carcinoma - Undifferentiated (anaplastic) carcinoma - Squamous cell carcinoma - Carcinoma with mixed features (specify) - Metastatic carcinoma - Non-Hodgkin’s lymphoma - Other
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Macrophages only
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Adenomatous nodule
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Adenomatous nodule
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Colloid nodule
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Focal hurthle cell metaplasia in goiter
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Hashimoto’s thyroiditis
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Subacute thyroiditis
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Radioactive iodine effect
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Follicular neoplasm
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Follicular neoplasm,trabecular type
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Hurthle cell neoplasm
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Papillary carcinoma
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Papillary carcinoma
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Papillary carcinoma,follicular variant, Giemsa stain
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Papillary carcinoma,follicular variant , Pap.stain
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Poorly differentiated carcinoma
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Medullary carcinoma, Pap stain
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Medullary carcinoma, Giemsa stain
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Medullary carcinoma, immunoreactive for calcitonin
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Anaplastic carcinoma
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Squamous cell carcinoma
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Metastatic renal cell carcinoma
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MALT lymphoma
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ReferencesReferences: : 11 . .National Cancer Institute (NCI), Thyroid Fine needleNational Cancer Institute (NCI), Thyroid Fine needle
aspiration state of the science, conference in 2007aspiration state of the science, conference in 2007 . .
22 . .Edmond S. Cibas, Barbara S. Ducathman. CYTOLOGYEdmond S. Cibas, Barbara S. Ducathman. CYTOLOGY , ,
diagnostic principles and clinical correlates, saundersdiagnostic principles and clinical correlates, saunders , ,
33rd rd edition,2009edition,2009..
33 . .Marluce Bibbo, Acta Cytologica, volume 53, 489-490, 2009Marluce Bibbo, Acta Cytologica, volume 53, 489-490, 2009
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For more study on cytopathology of For more study on cytopathology of the thyroid gland refer to the CD inthe thyroid gland refer to the CD in
this subject prepared by the Societythis subject prepared by the Society . .
The Members may call for a free copyThe Members may call for a free copy
from ISCC office in Isfahanfrom ISCC office in Isfahan . .
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