cytopathology challenge! weekly cases
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Cytopathology Challenge! Weekly Cases. Feb 1st, 2008 GYN SPECIAL EDITION NUMBER 2. 24 year old female. ThinPrep pap LSIL HSIL ASCUS Squamous Metaplasia Endocervical Cells. 1. 34 year old female. ThinPrep pap Reactive endocervical cells Squamous metaplasia ASCUS LSIL HSIL. 2. - PowerPoint PPT PresentationTRANSCRIPT
Feb 1st, 2008
GYN SPECIAL EDITION NUMBER 2
24 year old female. ThinPrep papA. LSILB. HSILC. ASCUSD. Squamous MetaplasiaE. Endocervical Cells
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34 year old female. ThinPrep papA. Reactive endocervical cellsB. Squamous metaplasiaC. ASCUSD. LSILE. HSIL
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34 year old female. ThinPrep papA. ASCUSB. LSILC. HSILD. Squamous MetaplasiaE. Reactive/Inflammatory
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29 year old female. ThinPrep papA. Squamous metaplasiaB. Reactive endocervical cellsC. ASC-USD. LSILE. HSIL
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32 year old female. ThinPrep papA. Squamous metaplasiaB. Reactive endocervical cellsC. ASC-USD. LSILE. HSIL
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23 year old female. ThinPrep papA. Squamous metaplasiaB. ParakeratosisC. LSILD. HSILE. SCCA
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18 year old female. ThinPrep papA. CMVB. HIVC. HPVD. HSVE. EBV
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52 year old female. ThinPrep papA. Reactive endocervical cellsB. Normal endometrial cellsC. AISD. AdenocarcinomaE. HSIL
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44 year old female. ThinPrep papA. Squamous metaplasiaB. Reactive endocervical cellsC. AtrophyD. LSILE. HSIL
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34 year old female. ThinPrep papA. ReactiveB. ASCUSC. LSILD. HSILE. Squamous Metaplasia
Answers1. D Squamous Metaplasia
• Nuclei not enlarged, smooth contours, NC ratio OK. Not HSIL.
2. A Endocervical cells• Small round and regular nuclei. Compare to Ques #1.
3. E Reactive• See the trichomonas organism!
4. D LSIL• Koilocytes!
5. D LSIL• Koilocytes!
6. B Parakeratosis• Sometimes associated with dysplasia
7. D HSV• Herpes Simplex Viral changes in Nucleus
8. D Adenocarcinoma• Crowded overlapping nuclei with prominent nucleoli. No “feathering” so not Adeno in situ (AIS)
9. E HSIL• High NC ratio, irregular nuclei. This actually turned out to be a SCCA on biopsy.
10. A Reactive• No dysplasia, just some squamous cells with neutrophils.