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Table of Contents Sponsors ............................................................................................................... 2 Welcome to CinC@Singapore in 2019! ................................................................ 3 Board of Directors ................................................................................................ 5 Local Organizing Committee ................................................................................ 6 Letter from the President .................................................................................... 7 Welcome to Maastricht ....................................................................................... 9 Maps .................................................................................................................. 11

General Map of Maastricht ............................................................................ 11 Map of Maastricht University (Sunday Symposium)...................................... 12 Map of the Conference Venue ....................................................................... 13

Transportation, Hotels and Practical Information ............................................. 14 Transportation ............................................................................................... 14

Getting around Maastricht ........................................................................ 15 Hotels ............................................................................................................. 16

General information .................................................................................. 16 Booking accommodation for CinC 2018..................................................... 16

Practical Information ..................................................................................... 17 Climate ....................................................................................................... 17 Money/currency ........................................................................................ 17 Calling and Emergency phone numbers .................................................... 17 Electric standards ....................................................................................... 17

Meals .............................................................................................................. 18 Accompanying Persons (Guests) ................................................................ 18

Conference Information..................................................................................... 19 General Information ...................................................................................... 19 Sunday Symposium ........................................................................................ 19 Conference site .............................................................................................. 20 Monday Social Program ................................................................................. 20 Tuesday Evening Reception ........................................................................... 21 For Authors and Speakers .............................................................................. 21

Oral Presentations ..................................................................................... 21 Poster Presentations .................................................................................. 21

Rosanna Degani Young Investigator Award ................................................... 22 Clinical Needs Translational (CTA) Award ...................................................... 22 PhysioNet/Computing in Cardiology Challenge 2018 .................................... 22 Manuscripts ................................................................................................... 23

CinC 2018 Program Overview ............................................................................ 24 CinC 2018 Program Details ................................................................................ 26

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Sponsors Computing in Cardiology 2018 is supported by several companies and academic partnerships. The Local Organizing Committee would like to thank the following partners:

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Welcome to CinC@Singapore in 2019!

Dear Colleagues & Friends,

It gives me great pleasure to announce that the International Conference in Computing in Cardiology 2019 will be held in Singapore. This is the second time that CinC is held outside of Europe and USA, and we are excited to host you at next year’s meeting.

The republic of Singapore is a city-state situated one degree north of the equator. Packed into its 130 square kilometres of real estate is a bustling metropolis embedded in lush tropical greeneries. Due to its horticultural richness, Singapore is also known as a City in a Garden. As a nation that is home to a wide plurality of cultures, ethnicities and religions, the diversity that you can experience in Singapore will be a unique experience in itself.

The conference venue will be located at the one-north precinct which houses world-class research facilities and business park spaces to support the growth of Biomedical Sciences, Infocomm Technology, Media, Physical Sciences and Engineering. The line up to next year’s programme includes a Sunday Symposium jointly organized with the National Heart Centre, Singapore to demonstrate the utility of computer- and computational-related research work in clinical practices. Due to the location of the conference, we expect significant participation and contribution of papers from colleagues in the Asia-Pacific Region.

We have planned for the passivist social event to include a visit to the Gardens by the Bay – a nature park spanning an awe-inspiring 101 hectares garden, set in the heart of the city. The activist social event will be conducted at the Mega Adventure Park where participants will enjoy adrenaline-pumping thrills on a zipline at 75 metres

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high, 450 metres long and heart-pounding speed of 60kph. To top it off, the Gala Dinner will feature unique Singapore cuisine which is as diverse as its culture.

At this point, we are working closely with the CinC Board of Directors to fine tune the conference programme so that it will be an exquisite experience for all of you. On behalf of the Organizing Committee, I look forward to welcoming you to Singapore next year. Be there!

With warmest regards,

Su Yi

Chairman, Organizing Committee, CinC 2019

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Board of Directors President Rob MacLeod, PhD SCI Institute, University of Utah Salt Lake City, Utah, USA Secretary Luca Mainardi, PhD Politecnico di Milano, Milano, Italy Treasurer J-P Couderc, PhD, MBA University of Rochester Rochester, NY, USA Registration Cristiana Corsi, PhD University of Bologna Bologna, Italy

Program Review Olaf Doessel, PhD Karlsruhe Institute of Technology Karlsruhe, Germany

Website and IT Dewar Finlay, PhD University of Ulster Belfast, UK

Young Investigator Competition María S Guillem, PhD Universitat Politècnica de València Valencia, Spain Poster Competition Pyotr Platonov, MD, PhD Lund University Lund, Sweden

Ex-Officio

Chair of the ESC Working Group on e-Cardiology: Joost Lumens, PhD Maastricht University Maastricht, The Netherlands

Past President/Sponsorships Pablo Laguna, PhD University of Zaragosa Zaragosa, Spain

The following positions are non-Elected:

Editor, Proceedings Christine Pickett SCI Institute, University of Utah Salt Lake City, Utah, USA

Executive Director, CinC Physionet Challenge Gari Clifford, DPhil Georgia Institute of Technology & Emory University, Atlanta, Georgia, USA. Director of Information Services Sheryl Prucka, MSEE Prucka Engineering, Inc Park City, UT, USA

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Local Organizing Committee Willem Dassen, PhD; Chair

Jordi Heijman, PhD; Co-chair

Henk Hoogervorst, MSc

Joost Lumens, PhD

Tammo Delhaas, MD, PhD

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Letter from the President Dear Participant,

Welcome to the 45th

Computing in Cardiology conference. Returning to The Netherlands is like coming home for CinC as this country hosted CinC three times in the past, always in Rotterdam, and we welcome this move to Maastricht, an extremely active and productive center for cardiology research. CinC first visited The Netherlands back in 1975, which was before even my time! The links to Maastricht are also very deep through our conference chair, Willem (Pim) Dassen, who also served a full term on the Board of Directors of CinC; we know we will be in good hands with Pim and his Co-chair, Jordi Heijman and we thank them for all their efforts over the past three years leading to CinC 2018!

Pim and Jordi have prepared an excellent meeting and social program, with a strong set of presentations selected from another large list of abstracts, which each year now demonstrates the increasing interest and huge impact of engineering in cardiology.

The Special Session initiative continues to highlight topics of new or renewed interest to our field and this year we again have three exciting sessions and topics:

1) Bioimpedance monitoring in cardiovascular diseases. 2) Personalized Medicine through integration of imaging and cardiac

modeling: state of the art and prospects. 3) Physics-based Versus Machine-learning Approaches to

Electrocardiographic Inverse Problems: Connections and Gaps.

This and other initiatives like the Clinical Translation and Young Investigator awards are features of CinC that we review each year, so please provide the Board of Directors with feedback on these initiatives as well as any other aspects of the conference. It is the Board's foremost commitment to guide the progress of our CinC organization in the coming years.

This year has been one of big changes in CinC organization with a number of experienced members completing their Board terms (maximum of nine years) to be replaced by a set of new members. Perhaps most challenging have been changes in the executive positions of President (Rob), Treasurer (Jean-Philippe Couderc), and Secretary (Luca Mainardi), two of whom are brand new Board members. We have also added a new technical editor, Christine Pickett, formalized the role of Gari Clifford as manager of the Physionet Challenge and added new Board members, Maria Guillem and Pyotr Platonov. Fortunately for us all, Past President Pablo Laguna and our past treasurer Victor Mor-Avi have been able to help with the (ongoing) transition.

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If I have learned one thing I my first year as President, it is the huge commitment of the Board members necessary to run CinC. When things run well, it is easy to forget how much is going on in the background and each attendee should take a moment and thank any Board members they meet.

Finally, I know Maastricht and CinC2018 will continue the long tradition and provide a scientifically stimulating meeting that will enable and motivate your research. I hope what you see motivates your participation next year as we move to the other side of the world to Singapore for CinC 2019.

Best wishes,

Rob MacLeod

President, Computing in Cardiology

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Welcome to Maastricht Dear Colleagues,

On behalf of the local organizing committee, we warmly welcome you from September 23-26, 2018 to the 45th Computing in Cardiology Conference in Maastricht, The Netherlands. Situated in the southernmost part of the Netherlands, Maastricht is located in the heart of Europe and the Euregion Meuse –Rhine. The city is only a short distance from both the Belgium and the German border and cities such as Liege, Aachen, Dusseldorf, Frankfurt and Brussels are therefore very near. Maastricht is easily accessible by plane, train and car. Maastricht is the oldest city in the Netherlands, but its university is the youngest and most international one, with 17.000 students from more than 120 different countries. Being the gastronomic capital of the Netherlands, the city also offers everything from Michelin-star establishments to traditional small local restaurants and pubs offering hospitality and quality food for every budget. The Sunday symposium will take place at the Faculty of Health, Medicine and Life Sciences of Maastricht University and the conference will be at the MECC conference centre, both located in the Randwyck area, within walking distance from your hotel, or easily reachable using the local public transportation, which will be free of charge with your CinC badge. The organizing committee, representing the departments of Cardiology, Biomedical Engineering and Knowledge Engineering has prepared an active scientific and social programme in and around Maastricht for Computing in Cardiology 2018. The Sunday symposium will focus on a hands-on experience with four advanced computer models and software tools in cardiology (CircAdapt, ECGSim, Myokit and SCIRun). After a word of welcome by the chairman of the Department of Cardiology and a short introduction, 250 computers are waiting, so you can discover the possibilities of various models to simulate, for example, cardiac contraction or electrical activation across various scales from ion-channel to whole heart. On Monday, the conference will start in the MECC conference centre. After the morning sessions all participants are transferred to the city centre for a two-hour lunch cruise on the river. In order to keep on schedule, everybody is requested to go directly to the busses at the end of their session. After returning ashore at 15:00 the various social activities will start. Eight different activist and passivist programmes have been organized, ranging from very lazy to breath-taking. The large number on

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your badge indicates the choice you made during registration, so cheating is not an option. At 19:00 all participants are expected at café Ipanema, next to the Bonnefanten museum. After a welcome drink and bite on the impressive stairs of the museum, CinC delegates have the option to participate in a short, guided tour to see the highlights of the museum, or can enjoy a private stroll. From 20:15 onwards, a walking dinner will be served with various choices to accommodate everybody’s taste and the bars will be opened. During the evening the Beverly Brothers will play their oldies but goodies. On Tuesday, the conference will continue at the MECC conference centre. After the afternoon sessions, CinC delegates are invited by the mayor of Maastricht, Annemarie Penn- te Strake, to attend a reception at the Maastricht town hall. During the evening you are free to enjoy Maastricht nightlife with its 400 bars and restaurants. On Wednesday, the final day of the conference, the program at the MECC will bring more exciting scientific presentations and will conclude with the final plenary session. In this session the winners of the Young Investigator Award, the Physionet/CinC Challenge Awards, the ESC-CinC Clinical Needs Translational Award, The Mortara Fellowships and the Bill & Gary Sanders Poster Awards will be announced, together with a preview on CinC2019 in Singapore. We are confident that on Wednesday evening we will look back on a successful and social CinC2018 that hopefully brought you at least as much inspiration and satisfaction as it gave us preparing the programme. Willem Dassen and Jordi Heijman

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Maps

General Map of Maastricht

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Map of Maastricht University (Sunday Symposium)

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Map of the Conference Venue

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Transportation, Hotels and Practical Information

Transportation

Maastricht is located in the heart of Europe, in the Meuse-Rhine Euro region. The city is surrounded by Belgium and Germany and close to France. Cities such as Liège, Aachen, Düsseldorf, Frankfurt and Brussels are therefore very near. Maastricht is easily accessible by plane, train and car.

Airports

Because of its central location in Europe, Maastricht has 8 international airports within 1.5 hours drive: Brussels Zaventem (intercontinental), Düsseldorf International (intercontinental), Maastricht Aachen Airport, Eindhoven Airport, Brussels/Charleroi Airport, Düsseldorf/Weeze Airport, Köln/Bonn Airport, Liège Bierset Airport.

Brussel Zaventem Airport is Belgium’s main airport and is situated only 100 kilometers from Maastricht. It has a wide variety of both European and Intercontinental flights and airlines. Düsseldorf International Airport is situated approximately 110 kilometers from Maastricht and has also a wide variety of European and Intercontinental flights. In addition, delegates can also fly to Amsterdam Schiphol. Maastricht has excellent train connections with Schiphol

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Airport, which takes approximately 2.5 hours. The train stops at Maastricht Central Station, which is situated in the city center.

Train

Maastricht has excellent train connections both national and international. Every 30 minutes there is an intercity train connection with Eindhoven, Utrecht and Amsterdam. Frequently there are connections to Liège (Belgium), Brussels (Belgium) and Aachen (Germany) where you can change to international trains – Thalys, TGV, Eurostar – to London, Paris and other European cities. Maastricht has three railway stations: Maastricht Central, Maastricht North and Maastricht Randwyck. From Central you can walk directly into the city centre where many hotels are located. Maastricht North gives you direct access to the city’s suburbs. The Maastricht Randwyck Station is located only 250 meters from the MECC Convention Centre, where CinC 2018 will take place. Also the Academic Hospital (azM), Maastricht University, Maastricht School of Management and many hotels are situated in the Randwyck station area. You can use http://www.9292ov.nl or http://www.ns.nl to plan your journey by train.

By car

Because of the central location of the city, Maastricht is also easy accessible by car from all directions.

From the north (Amsterdam, Utrecht, Eindhoven) E25/A2

From the west (Brussels, Hasselt) E40 > E25/A2 or E314/A2

From the south (Paris, Liège) E40 > E25/A2

From the east (Berlin, Düsseldorf, Köln/Bonn) A79

Getting around Maastricht

For your transportation in The Netherlands, including within Maastricht, the website http://www.9292ov.nl will help you select the best journey (train/bus). Note that with your conference badge, you will be able to take local city busses for free during the conference. However, if you want to take a taxi, you can call one of the following companies:

Taxi Frenske: +31 (0)43 363 6362

Avantax: +31 (0)43 450 6464

Budgettax:i +31 (0)1862 2390

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Hotels

General information

With over 4,100 hotel rooms available, Maastricht has a wide variety of stunning places to rest up for the CinC delegates in 2018. Similar to the city’s historic and international character, the places to stay are a mix of historic boutique hotels, charming – romantic hotels and modern design hotels. Whether you would like a hotel in the lively city centre or in a nice and quiet part of the city, Maastricht has all there is to have a marvelous stay. Our gastronomic character guarantees the best service and will make the CinC delegates feel at home. In the city centre – on both sides of the Meuse – you’ll find beautiful historic hotels typical of Maastricht. All hotels are very close to the various squares the city has, which makes it easy to go out for a drink after the conference. Most hotels are also very close to each other so you will meet other delegates on the doorstep of your hotel.

In the area of the MECC, which is only 15 minutes from the city centre, you can find several international hotel chains with modern conference hotels.

Booking accommodation for CinC 2018

In close consultation with the organization, MECC Hotel Services has reserved rooms in different hotels in Maastricht and surroundings at very competitive rates. There are no extra costs, and no reservation costs when using this service.

The most comfortable way to book your room in Maastricht is by using our online reservation system (accessible through http://www.cinc2018.org). You can sort by area and hotel classes. A map shows you the location of the hotel relative to the MECC Maastricht. Of course you can also find additional information on each hotel, such as facilities, rates and pictures.

If you want to reserve 9 rooms or more of if you do not want to reserve your room on-line, you can e-mail us mhs@mecc.nl or call us, telephone number +31 43 3838361.

If you book your room through MECC Hotelservices you will have the option to register for free transportation from and to the Brussels Zaventem Airport, as indicated on the website (registration required).

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Practical Information

Climate

The climate in Maastricht is typically mild, with daily maximum temperatures around 18°C (approx. 65°F) and low temperatures around 10°C (or 50°F). In the evening, we recommend using a jacket or a pullover. Rain is always a possibility, with an average of 65 mm of rain during the month of September. Nonetheless, most people bicycle or walk to get around town year round!

Money/currency

Credit cards (Mastercard and Visa) as well as debit cards (Maestro) are accepted in many shops, hotels, and restaurants. ATMs can be found throughout the city.

Bank branches and exchange offices (e.g., at the central station) handle currency exchange transactions and traveler's cheques. Whatever you are buying, prices shown include VAT. Gratuities are not mandatory, but certainly appreciated when receiving good service at restaurants, etc.

Calling and Emergency phone numbers

The country code for The Netherlands is +31. In case of emergency, please call the European emergency number 112.

Electric standards

220 Volts - 50 Hertz

Internet Access

Every participant in the Sunday symposium will receive a personal login when registering on-site that can also be used to access the WiFi. For those using Eduroam, this network is also available at the location of the Sunday symposium. Within the MECC conference area, a wireless network will be available free of charge. The only device you need is a WiFi-enabled laptop or smartphone. Should you need assistance in getting connected, please ask the nearest volunteer for help.

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Meals

The delegates will not have to worry about meals. To ensure that the meeting is running in a timely fashion, the attendees are kindly asked to proceed quickly to the buffet immediately after the session finishes.

• The Sunday symposium concludes with a drink at 17:00 in the building of the faculty of Health, Medicine and Life Sciences, Maastricht University.

• On Monday afternoon at 13:00 (sharp!), all participants will be transferred to the city centre for a two-hour lunch cruise on the river.

• After the physical social activities on Monday afternoon, there will be an opportunity to enjoy a drink and some art at the Bonnenfanten museum (see General Map of Maastricht for its location) at 19:00. From 20:15 onwards, a walking dinner will be served with various choices to accommodate everybody’s taste.

• On Tuesday, a buffet lunch will be provided at the MECC conference. After Tuesday’s sessions, participants are invited to travel to the central market in Maastricht to enjoy a reception offered at 18:30 by the city hall. (Group transportation is not provided for this visit). .

• On Wednesday, a buffet lunch will be served at the conference site after the morning sessions and in parallel with the Poster session.

Accompanying Persons (Guests)

The accompanying person (guest) registration allows the guest to attend:

• The reception on Sunday late afternoon (after the hands-on session) at the Faculty of Health Medicine and Life Sciences of Maastricht University.

• The Monday social event, starting at 13:00 with a lunch cruise, participation in one of the activities and in the evening program starting at 19:00 at the Bonnefanten museum and Café Ipanema (see General Map).

• The Tuesday reception at the City Hall at 18:30 (see General Map).

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Conference Information

General Information

The conference registration and information desk will be located at Maastricht University on Sunday and near the entrance in the MECC Conference Centre on the other days. The registration desk will be labelled with the CinC sign and will be open during the following hours:

• Sun, 23rd

September 13:00 – 18:00 • Mon, 24

th September 08:00 – 12:00

• Tues, 25th

September 08:00 – 17:30 • Wed, 26

th September 08:00 – 17:30

Sunday Symposium

The Sunday symposium will take place at the Faculty of Health, Medicine and Life Sciences of Maastricht University (Universiteitssingel 50) located in the Randwyck area, within walking distance from your hotel, or easily reachable using the local public transportation, which will be free of charge with your CinC badge. The symposium will focus on a hands-on experience with four advanced computer models and software tools in cardiology (CircAdapt, ECGSim, Myokit and SCIRun). After a word of welcome by the chairman of the Department of Cardiology and a short introduction, 250 computers are waiting, so you can discover the possibilities of various models to simulate, for example, cardiac contraction or electrical activation across various scales from ion-channel to whole heart. Personal log-in information will be provided to everyone who registered for the Sunday symposium. Of course, you can also bring you own laptop. • 13:00: Registration opens • 14:00: Word of welcome and introduction to simulation models • 15:00: Start hands-on session • 17:00: Drinks • 18:00: End of program

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Conference site

The 45th

annual international conference of Computing in Cardiology will take place at the Maastricht Exhibition and Conference Centre (MECC), from Monday, September 24

th through Wednesday, September 26

th, 2018. All lectures, poster

sessions and lunches are situated at Lobby level 0 (see “Map of the Conference venue”).

The MECC is easily reachable by bus, but is only a short walk away from most hotels. Please refer to the map “General map of Maastricht” and “Map of Maastricht University”. The building and lecture rooms will be clearly marked with Computing in Cardiology signs.

Monday Social Program

All social program participants are required to wear their CinC badges.

Each year at CinC, Monday afternoon is set aside for a social event. This is an important part of the conference program as it allows attendees to meet each other in a more informal setting away from the scientific sessions.

On Monday, the conference will start in the MECC Conference Centre. After the morning sessions all participants are transferred to the city centre for a two-hour lunch cruise on the river, starting at 13:00 h sharp. In order to keep on schedule, everybody is requested to go directly to the busses at the end of their session. Depending on the social activity you selected you will disembark at stop I or II. Around 15:00 the various social activities will start. In case you missed the cruise, this is a point where you can re-enter. Eight different activist and passivist programmes have been organized, ranging from very lazy to breath-taking. The large number on your badge indicates the choice you made during registration, so cheating is not an option. After the social activities, all participants are expected at 19:00 h at the Bonnefanten museum. After a welcome drink and bite on the impressive stairs of the museum, CinC delegates have the option to participate in a short guided tour to see the highlights of the museum, or can enjoy a private stroll. From 20:15 onwards, a walking dinner will be served in Café Ipanema, which is attached to the museum, with various choices to accommodate everybody’s taste and the bars will be opened. During the evening the Beverly Brothers will play their oldies but goodies.

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Tuesday Evening Reception

The mayor of the city has invited all CinC participants and their accompanying guests for a reception at the city hall at 18:30 which is located at the Market (see General Map). This impressive Dutch Baroque building in the middle of the Market square has a rich 18th-century décor. It is home to many art treasures and antiques.

For Authors and Speakers

Oral Presentations

The time allocated for each oral presentation is 10 minutes, followed by 5 minutes for discussion (except for Physionet Challenge sessions). Speakers are expected to adhere strictly to this schedule, which will be enforced by session chairpersons to finish sessions on time and to permit participants to move successfully from one parallel session to another.

• All conference rooms will be equipped with a computer projection system (projector and PC with Windows 10, Powerpoint 2013, Windows Media Player and Adobe Acrobat Reader).

• Due to Powerpoint version issues, PDF format is preferred. • Laptops can be connected through HDMI or VGA. MacBook users should

make sure to bring a adapter.

Speakers are required to allow adequate time before their session to load and check their presentation. Also, speakers are required to meet with their session chairpersons in the scheduled conference room at least 10 minutes before the beginning of the session. It is a good idea to ensure that the chairperson knows how to pronounce your name correctly.

Poster Presentations

Poster sessions will take place in the main conference area. Poster session P71-P7D is on Tuesday, 25th September from 16:00 onwards, and Poster session PA1-PA8 is on Wednesday, 26th September, from 12:15-13:45. Authors are required to be present at their posters during their assigned session to discuss their work with other conference attendees.

• Check in: Authors presenting posters must check in with the session chair in the exhibition centre during the 30 minutes before the poster sessions in which their presentations are scheduled.

• Posters may be hung after 8:00 and prior to the start of the poster sessions on the day of presentation (either Tuesday or Wednesday).

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• Posters stands and mounting material will be provided. The poster boards will be approximately 95 x 136 cm tall (w x h). As such, posters should be prepared in portrait format, e.g., in A0 size (84.1 x 118.9 cm)

• Posters are grouped by subject area, and each poster should be placed on the stand assigned to it (marked with a card corresponding to the page number of the abstract in the program book)

• If an author is not present to discuss a poster, it will not be published in the proceedings.

• Posters must be removed at the end of the day of presentation.

Rosanna Degani Young Investigator Award

Computing in Cardiology hosts an annual competition to encourage young investigators and to provide a living memorial to Rosanna Degani.

Finalists in the competition will present their work in session M1, at 8:45 am on Monday, September 24 in the main auditorium (Room 0.4-0.5, see Map of the MECC Conference Center). The name of the winner will be announced during the closing plenary session in the same venue on Wednesday.

Clinical Needs Translational (CTA) Award

Computing in Cardiology and the Working Group on e-Cardiology of the European Society of Cardiology (ESC) support this award designed to encourage participation of multidisciplinary research teams, with emphasis on the potential clinical applicability and impact of the research.

A representative of the winning team will present their work at the beginning of the Closing Plenary Session on Wednesday, September 26, 2018 in Room 0.4-0.5 (see Map of the MECC Conference Center for details).

PhysioNet/Computing in Cardiology Challenge 2018

Since 2000, Computing in Cardiology has annually issued a Physionet Challenge in cooperation with Physionet, part of the NIH sponsored Research Resource for Complex Physiologic Signals. The title of this year’s challenge is “You Snooze, You Win”, which aims to correctly classify sleep arousals from physiological parameters (including the ECG) recorded from subjects in a sleep laboratory at the Massachusetts General Hospital. The challenge sessions are:

Oral sessions S83 & S93

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Poster session PA1

Manuscripts

Computing in Cardiology will publish the conference proceedings containing the complete manuscripts of all presentations made at the conference. The complete proceedings will be freely available via the CinC Web site (http://www.cinc.org). The proceedings will also be published by IEEE in the IEEEXplore digital library. For any questions about manuscripts, consult the CinC web site http://www.cinc.org or contact via email editor@cinc.org.

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CinC 2018 Program Overview

Sunday, September 23, 2018

13:00 Symposium Registration 14:00 Symposium Introduction 15:00 Symposium Activity 17:00 Welcome Reception

Monday, September 24, 2018

8:30 Welcome to CinC 2018 8:45 M1: Rosanna Degani Young Investigator Finals 10:15 Coffee Break 10:45 S21: Novel Quantification Approaches from Cardiovascular Imaging 10:45 S22: Special Session: Bioimpedance Monitoring 10:45 S23: Cardiovascular Mechanics 10:45 S24: Balistocardiography, Seismocardiography, and PPG 12:15 Social Event

Tuesday, September 25, 2018

8:30 S31: Cardiac Function from Imaging 8:30 S32: Technical Progress in ECG Imaging 8:45 S33: AF Drivers & Targets 8:30 S34: Medical Informatics Technology 10:00 Coffee Break 10:15 S41: Heart Rate Variability: Methods 10:15 S42: ECG Processing of Exercise 10:15 S43: ECG Analysis for AF 10:15 S44: Special Session: Personalized Medicine 11:45 Lunch 12:45 S51: Heart Rate Variability: Applications 12:45 S52: Modeling Ion Channels and Cells 12:45 S53: AF Detection and Simulation 12:45 S54: ECG Processing and Artificial Intelligence 14:15 Coffee Break 14:30 S61: Modeling Ensembles of Cells 14:30 S62: Special Session: Physics vs Machine Learning Based

Approaches in ECGI 14:30 S63: Cardiorespiratory Autonomic Iterations 14:30 S64: ECG Processing of Ventricular Repolarization 16:00 P7: Poster Session

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16:00 P71: Modeling Ion Channels, Cells and Fetal Signals 16:00 P72: Modeling Drug Effects and Mutations 16:00 P73: Mechanisms of Reentry and Fibrillation 16:00 P74: Whole Heart Modeling 16:00 P75: Analysis and Mapping in Arrhythmia 16:00 P76: Ischemia and Infarct Analysis with ECG and Imaging 16:00 P77: New Approaches and Applications of ECGI 16:00 P78: ECG Waveform Analysis 16:00 P79: ECG Heterogeneity 16:00 P7A: Wavelet Based Analysis of ECG 16:00 P7B: ECG Fiducial Detection 16:00 P7C: Denoising ECT 16:00 P7D: ECG Mapping

Wednesday, September 26, 2018

8:30 S81: Modeling Arrhythmias and Defibrillation 8:30 S82: Cardiac Autonomic Iterations 8:30 S83: Challenge I 8:30 S84: ECG Processing of Ventricular Repolarization 10:00 Coffee Break 10:15 S91: ECGI in Clinical Applications 10:15 S92: Cardiac Arrest & Resuscitation 10:15 S93: Challenge II 10:15 S94: ECG Processing and Arrhythmias 11:45 Lunch 12:15 PA: Poster Session with Lunch 12:15 PA1: Challenge Posters 12:15 PA2: Heart Rate Variability 12:15 PA3: Atrial Fibrillation 12:15 PA4: Cardiovascular Imaging 12:15 PA5: System Study 12:15 PA6: CV Mechanics 12:15 PA7: Medical Informatics & Technology 12:15 PA8: Tissue Modeling 13:45 SB1: Whole Heart Modeling 13:45 SB2: Sleep and Autonomic Nervous System 13:45 SB3: Ventricular Arrhythmias: Detection and Ablation 13:45 SB4: Analysis of Ischemia 15:15 Break 15:30 MD: Closing Plenary 16:30 Closing Ceremony (until 17:15)

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CinC 2018 Program Details

Monday, September 24, 2018 8:45 M1 Rosanna Degani Young Investigator Finals Chairs: Olaf Doessel and Jordi Heijman Room: 0.4/0.5 Main Auditorium 1-212 Detecting Mechanical Alternans in the Photoplethysmography 8:45-9:05 Tudor Besleaga*, Nicola Toschi, Antonio Canichella, Andreas

Demosthenous, Pier Lambiase, Michele Orini

2-115 Risk Assessment of All-Cause Mortality in Patients with an Implantable Cardioverter Defibrillator Using a Novel QRS Fragmentation Score 9:05-9:25 Griet Goovaerts*, Sibasankar Padhy, Carolina Varon, Bert Vandenberk, Rik Willems, Sabine Van Huffel

3-94 In Silico Safety Pharmacology on Intersubject Variability Population of Models: A Regression Model Approach 9:25-9:45 Ana Maria Sanchez de la Nava*, Alejandro Liberos, Ismael Hernαndez-Romero, Maria de la Salud Guillem Sαnchez, Felipe Atienza, Francisco Fernandez-Aviles, Andreu M. Climent

4-329 Mathematical Modeling of Nonselective Channels: Estimating Ion Current Fractions and Their Impact on Pathological Simulations 9:45-10:05 Eike Moritz Wόlfers*, Peter Kohl, Gunnar Seemann

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Monday, September 24, 2018 10:45 S21 Novel Quantification Approaches from Cardiovascular Imaging Chairs: Teo Soo Kng and Cristiana Corsi Room: 0.8 Rome 5-41 Evaluation of Left Ventricular Diastolic Function Using 4D Flow Magnetic Resonance Imaging 10:45-11:00 Sophia Houriez--Gombaud-Saintonge*, Emilie Bollache, Gilles Soulat, Youssef Alattar, Jιrτme Lamy, Kevin Bouaou, Umit Gencer, Alban Redheuil, Elie Mousseaux, Yasmina Chenoune, Nadjia Kachenoura

6-260 Development of a New Approach for the Assessment of Complex Blood Flow Patterns in the Left Atrium From 4D Flow MRI 11:00-11:15 Enrico Soldati*, Thomas Dietenbeck, Alban Redheuil, Alessandro Masci, Sophia Houriez, Gombaud Saintonge, Nadjia Kachenoura Kachenoura2, Cristiana Corsi

7-393 Quantification of Left Atrium Fibrosis From Late Gadolinium Enhanced MRI in Atrial Fibrillation 11:15-11:30 Alice Andalς*, Claudio Fabbri, Maddalena Valinoti, Alessandro Masci, Cristiana Corsi

8-278 Automated Scar Segmentation From Cardiac Magnetic Resonance-Late Gadolinium Enhancement Images Using a Deep-Learning Approach 11:30-11:45 Sara Moccia, Riccardo Banali, Chiara Martini, Giuseppe Muscogiuri, Gianluca Pontone, Mauro Pepi, Enrico Caiani*

9-218 Semiautomatic Vendor Independent Software for Assessment of Local Arterial Stiffness 11:45-12:00 Madalina Negoita, Shima Abdullateef*, Alessandro Giudici, Alun D Hughes, Kim H Parker, Ashraf W Khir

10-318 Uncalibrated Real-Time Stroke Volume Estimation in MRI Using the Magnetohydrodynamic Effect ? 12:00-12:15 Charles-Antoine Robert, Emilien Micard, Julien Oster*

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Monday, September 24, 2018 10:45 S22 Special Session: Bioimpedance Monitoring Chairs: Christophe Smeets and Chris van Hoof Room: 0.9 Athens 11-397 Bioimpedance for Healthcare and Lifestyle Applications 10:45-11:15 Willemijn Groenendaal* 12-398 A Wearable Thoracic Impedance Sensor for Acutely Decompensated Heart Failure Monitoring 11:15-11:30 Christophe Smeets* 13-399 Wearable Bio-Impedance Monitoring During Hemodialysis for Chronic Kidney Disease 11:30-11:45 Melanie Schoutteten* 14-396 An Optimal Electrode Configuration to Measure Forced Expirations Using a Wearable Bioimpedance Device 11:45-12:00 Hélène De Cannière*, Karlien Geboers, Christophe JP Smeets, Willemijn Groenendaal, Seulki Lee, Gabriel Squillace, Lars Grieten, Pieter Vandervoort

15-404 Bioimpedance Monitoring Discussion 12:00-12:15 Christophe Smeets*, Christopher Van Hoof

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Monday, September 24, 2018 10:45 S23 Cardiovascular Mechanics Chairs: Joost Lumens and Olaf Doessel Room: 0.4 Brussels 16-28 Classification Model of Heart Transplant Outcomes Based on Features of Left Ventricular Functional Geometry 10:45-11:00 Tatiana Chumarnaya*, Sergey P. Mikhaylov, Eduard M. Idov, Olga Solovyova

17-235 Using Observed Contrast Motion During Cardiac Catheterization to Tune Patient Specific Coronary Blood Flow Simulations 11:00-11:15 Stephen Moore*, Olivia Smith, Kerry Halupka, Sergiy Zhuk 18-237 Towards Real-Time 3D Coronary Hemodynamics Simulations During Cardiac Catheterisation 11:15-11:30 Stephen Moore*, Kerry Halupka, Sergiy Zhuk 19-274 Mechano-Chemical Interactions in the Isotonic Twitch: A Modeling Study 11:30-11:45 Lauren Dupuis*, Joost Lumens, Theo Arts, Tammo Delhaas 20-295 Relationship Between Electrical Instability and Pumping Performance During Ventricular Fibrillation: Computation Study 11:45-12:00 Daun Jeong*, Ki Moo Lim 21-339 Reverse Electrical Remodeling Assessed by High- Frequency QRS Dyssynchrony and QRS Duration 12:00-12:15 Pavel Leinveber*, Josef Halamek, Pavel Jurak, Magdalena Matejkova, Jolana Lipoldova, Miroslav Novak

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Monday, September 24, 2018 10:45 S24 Balistocardiography, Seismocardiography, and PPG Chairs: Kouhyar Tavkolian and Enrico Caiani Room: 0.5 Paris 22-337 Multichannel Seismocardiography: A Novel Method for Investigating the Seismocardiogram 10:45-11:00 Kim Munck*, Samuel Emil Schmidt, Kasper Sørensen, Johannes Struijk

23-110 Machine Learning Based Classification of Myocardial Infarction Conditions Using Smartphone-derived Seismo- and Gyrocardiography 11:00-11:15 Saeed Mehrang*, Mojtaba Jafari Tadi, Olli Lahdenoja, Matti Kaisti, Tuija Vasankari, Tuomas Kiviniemi, Juhani Airaksinen, Mikko Pankaala, Tero Koivisto

24-111 Force-Interval Relationships of the Heart Measured With Photoplethysmography During Atrial Fibrillation 11:15-11:30 Linda M. Eerikδinen*, Alberto Bonomi, Lukas Dekker, Fons Schipper, Rik Vullings, Ronald M. Aarts

25-186 Unsupervised Artefact Detection and Screening Using Emfit Sensor in Patients With Sleep Apnea 11:30-11:45 Dorien Huysmans*, Bertien Buyse, Dries Testelmans, Sabine Van Huffel, Carolina Varon

26-203 Determining the Respiratory State From a Seismocardiographic Signal--A Machine Learning Approach 11:45-12:00 Christian Ulrich*, Martin Jensen, Rolf Hansen, Kouhyar Tavakolian, Farzad Khosrow-Khavar, Andrew Blaber, Kasper Sørensen, Samuel Emil Schmidt

27-134 Sleep Apnea Detection Using Pulse Photoplethysmography 12:00-12:15 Margot Deviaene*, Jesus Lazaro, Dorien Huysmans, Dries Testelmans, Bertien Buyse, Sabine Van Huffel, Carolina Varon

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Tuesday, September 25, 2018 8:30 S31 Cardiac Function from Imaging Chairs: Nadjia Kachenoura and Enrico Caiani Room: 0.8 Rome 28-261 Quantification of the Anatomical Remodelling of the Ventricles of Arrhythmogenic Right Ventricular Cardiomyopathy Patients, an MRI Based Imaging Study 8:30-8:45 Peter Marinov*, Ernesto Zacur, Pier Lambiase, Vincente Grau, Blanca Rodriguez, Alfonso Bueno-Orovio, Michele Orini

29-167 Characterization of Pulmonary Hypertension using Right Ventricular Regional Curvedness Derived from CMR Imaging 8:45-9:00 Soo Kng Teo*, Xiaodan Zhao, Ru San Tan, Liang Zhong, Yi Su 30-362 A Semiautomated Approach for the Quantification of the Left Ventricle Chamber Volumes From Cine Magnetic Resonance Images 9:00-9:15 Claudio Fabbri*, Keigo Kawaji, Noreen Nazir, Victor Mor Avi, Amit Patel, Cristiana Corsi

31-169 Reconstruction of Patient-Specific Left Atrium Geometry From CMR Imaging 9:15-9:30 Soo Kng Teo*, Xiaodan Zhao, Ru San Tan, Liang Zhong, Yi Su 32-366 Anatomically-Induced Fibrillation in a 3D Model of the Human Atria 9:30-9:45 Mark Potse* 33-258 Development of New Left Atrial Anatomical Models for the Study of the Left Atrial Appendage Implications in Atrial Fibrillation 9:45-10:00 Alessandro Masci*, Lorenzo Barone, Corrado Tomasi, Cristiana Corsi

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Tuesday, September 25, 2018 8:30 S32 Technical Progress in ECG Imaging Chairs: Pietro Bonizzi and Peter van Dam Room: 0.9 Athens 34-374 Effect of Segmentation Variation on ECG Imaging 8:30-8:45 Jess Tate*, Nejib Zemzemi, Wilson Good, Peter van Dam, Dana Brooks, Rob MacLeod

35-70 Effects of ECG Signal Processing on the Inverse Problem of Electrocardiography 8:45-9:00 Laura Bear*, Yesim Serinagaoglu Dogrusoz, Jana Svehlikova, Jaume Coll-Font, Wilson Good, Eelco van Dam, Rob MacLeod, Emma Abell, Richard Walton, Ruben Coronel, Remi Dubois

36-309 Reduction of Effects of Noise on the Inverse Problem of Electrocardiography With Bayesian Estimation 9:00-9:15 Yesim Serinagaoglu Dogrusoz*, Laura R Bear, Jana Svehlikova, Wilson Good, Jaume Coll-Font, Eelco van Dam, Remi Dubois, Robert S MacLeod

37-335 Robustness of Reduced Order Nonparametric Model for Inverse ECG Solution Against Modeling and Measurement Noise 9:15-9:30 Φnder Nazım Onak*, Yesim Serinagaoglu Dogrusoz, Gerhard Wilhelm Weber

38-88 Epicardial Isochrones and a New High-Frequency ECG Isochrones Technique 9:30-9:45 Pavel Jurak*, Uyên Châu Nguyên, Ivo Viscor, Petr Andrla, Filip Plesinger, Frits Prinzen, Josef Halamek, Pavel Leinveber

39-343 Electrocardiographic Imaging: An Improved Algorithm for Evaluating the Global Activation Time in Patient- Specific Geometry 9:45-10:00 Shijie Zhou*, John Sapp, Amir AbdelWahab, Milan Horacek

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Tuesday, September 25, 2018 8:30 S34 Medical Informatics Technology Chairs: Nuria Ortigosa Room: 0.5 Paris 45-352 Automatic Diagnoses Detection in Free Text ECG Medical Report 8:30-8:45 Derick Oliveira*, Gabriela Paixγo, Eder Figueiredo, Paulo Gomes, Milton Ferreira, Jιssica Canazart, Antonio Ribeiro, Wagner Meira

46-249 Predictive Models for Risk Assessment of Worsening Events in Chronic Heart Failure Patients 8:45-9:00 Maria Carmela Groccia, Danilo Lofaro, Domenico Conforti*, Angela Sciacqua

47-376 Real-Time ECG Monitoring for Patients With Implantable Pacemaker – A Review of Current Status 9:00-9:15 John Wang* 48-78 An Algorithm to Sample an Anatomy With Uncertainty 9:15-9:30 Cesare Corrado*, Steven Williams, Iain Sim, Sam Coveney, Mark O'Neill, Richard Wilkinson, Jeremy Oakley, Richard Clayton, Steven Niederer

49-342 Heart Sounds Obtained With Noncontact Continuous- Wave Echo Doppler 9:30-9:45 Johannes Struijk*, Dagbjört Helga Eiriksdσttir, Αsgerdur Arna Pαlsdσttir, Samuel Emil Schmidt

50-276 A Comparative Phonocardiography Study: Two Wavelet Based Methods for Fetal Heart Sound Detection 9:45-10:00 Elisavet Koutsiana*, Leontios Hadjileontiadis, Ioanna Chouvarda, Ahsan Khandoker

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Tuesday, September 25, 2018 8:45 S33 AF Drivers & Targets Chairs: Andreu Climent and Axel Loewe Room: 0.4 Brussels 40-137 A K-Nearest Neighbour Classifier for Predicting Catheter Ablation Responses Using Noncontact Electrograms During Persistent Atrial Fibrillation 8:45-9:00 Xin Li, Gavin S Chu, Tiago Paggi de Almeida, João Salinet, Amar R Mistry, Zakariyya Vali, Peter J Stafford, Fernando S Schlindwein*, G. Andrι Ng

41-194 Propagation Pattern Analysis of Panoramic Mapping From Patients With Persistent Atrial Fibrillation 9:00-9:15 Nolwenn Tan*, Elizabeth Cheng, Martyn Nash, Martin Stiles, Stephan Willems, Pawel Kuklik, Jichao Zhao

42-138 Dominant Frequency Variability Mapping for Identifying Stable Drivers During Persistent Atrial Fibrillation Using Noncontact Mapping 9:15-9:30 Xin Li, Gavin S Chu, Tiago Paggi de Almeida, Joγo Salinet, Amar R Mistry, Zakariyya Vali, Peter J Stafford, Fernando S Schlindwein*, G André Ng

43-279 Reentrant Activity Detection During Atrial Fibrillation in Activation-Based 2D Mapping Agrees With Phase-Based 3D Mapping 9:30-9:45 Miguel Rodrigo*, Christopher AB Kowalewsky, Andreu M. Climent, Ismael Hernandez-Romero, Tina Baykaner, Wouter- Jan Rappel, Maria S Guilem, Sanjiv M Narayan, Felipe Atienza

44-394 Spatiotemporal Stability of Peak Bipolar Electrogram Entropy Regions in Sustained Human and Animal Atrial Fibrillation: Implications for Atrial Fibrillation Mechanism and Mapping 9:45-10:00 Dhani Dharmaprani*, Andrew McGavigan, Darius Chapman, Rayed Kutieleh, Shivshankar Thanigaimani, Lukah Dykes, Jonathan Kalman, Prashathan Sanders, Kenneth Pope, Pawel Kuklik, Anand Ganesan

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Tuesday, September 25, 2018 10:15 S41 Heart Rate Variability: Methods Chairs: Michele Orini and Fernando Schlindwein Room: 0.8 Rome 51-146 Vector-Based Analysis of the Similarity Between Breathing and Heart Rate During Paced Deep Breathing 10:15-10:30 Denis Kleyko, Evgeny Osipov, Urban Wiklund* 52-179 Intrinsic Complexity of RR and QT Intervals at the Cellular Level 10:30-10:45 Jiyeong Kim*, Ilya Potapov, Disheet Shah, Jukka Kuusela, Katriina Aalto-Setälä, Esa Räsänen

53-190 Parametric Estimation of Entropy Using Higher Order Markov Chains for Heart Rate Variability Analysis 10:45-11:00 Corrado Ameli*, Roberto Sassi 54-219 Robust Estimation of the Scaling Exponent in Detrended Fluctuation Analysis of Beat Rate Variability 11:00-11:15 Matti Molkkari*, Esa Räsänen 55-289 Validity of Venous Waveform Signal for Heart Rate Variability Monitoring 11:15-11:30 David Hernando*, Reid McCallister, Jesus Lazaro, Kyle Hocking, Eduardo Gil, Pablo Laguna, Colleen Brophy, Raquel Bailón 56-321 Investigating Phasic Activity of Time-Varying High-Order Spectra: A Heartbeat Dynamics Study During Cold- Pressure Test 11:30-11:45 Shadi Ghiasi*, Alberto Greco, Mimma Nardeli, Vincenzo Catrambone, Riccardo Barbieri, Pasquale Scilingo, Gaetano Valenza

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Tuesday, September 25, 2018 10:15 S42 ECG Processing of Exercise Chairs: Cees Swenne and Richard Gregg Room: 0.9 Athens 57-382 Analysis of ECG in Athletes Running in Mountain Route Conditions 10:15-10:30 Pedro Gomis*, Eduard Guasch, Alexandre Perera, Lluis Mont, Pere Caminal

58-143 Signal-Level Fusion with Convolutional Neural Networks for Capacitively Coupled ECG in the Car 10:30-10:45 Christoph Hoog Antink, Erik Breuer, Durmus Umutcan Uguz*, Steffen Leonhardt

59-299 Autonomic Nervous System Effects on the Atrioventricular Conduction Time - Heart Period Relationship During Physical Exercise and Passive Recovery 10:45-11:00 Grégory Blain, Guillaume Ducrocq, Mathilde Peraldi, Olivier Meste*

60-364 Selection of Reliable RR Interval Segments Using Hidden Semi-Markov Models 11:00-11:15 Matthieu Doyen, Di Ge, Guy Carrault*, Alfredo Hernandez 61-210 Evaluation of a Continuous ECG Quality Indicator Based on the Autocorrelation Function 11:15-11:30 Jonathan Moeyersons*, Dries Testelmans, Bertien Buyse, Rik Willems, Sabine Van Huffel, Carolina Varon

62-38 GPU-Based Segmented-Beat Modulation Method for Denoising Athlete Electrocardiograms During Training 11:30-11:45 Amnah Nasim, Edoardo Della Santa, Damiano Tanchi, Agnese Sbrollini, Ilaria Marcantoni, Micaela Morettini*, Laura Burattini

- 37 -

Tuesday, September 25, 2018 10:15 S43 ECG Analysis for AF Chairs: Leif Sornmo and Juan Pablo Martinez Room: 0.4 Brussels 63-36 Shape Analysis of Consecutive Beats May Help in the Automated Detection of Atrial Fibrillation 10:15-10:30 Filip Plesinger*, Petr Andrla, Ivo Viscor, Josef Halamek, Veronika Bulkova, Pavel Jurak

64-87 P-Wave Analysis for Atrial Fibrillation Detection Using a Neural Network Clustering Algorithm 10:30-10:45 Reza Firoozabadi*, Richard Gregg, Saeed Babaeizadeh 65-150 The Signal Averaged P-Wave Is Able to Indicate the Clinical State of Atrial Fibrillation Disease 10:45-11:00 Matthias Zink*, Stef Zeemering, Martijn Gilbers, Laurent Pison, Ulrich Schotten

66-266 Atrial Fibrillation Detection by Exploiting the Spectral and Temporal Characteristics of ECG Signals With the Long Short-Term Memory Model 11:00-11:15 Yen-Chun Chang*, Sau-Hsuan Wu, Li-Ming Tseng, Hsi-Lu Chao 67-31 Atrial Fibrillation Spatiotemporal Complexity Is Affected by Pulmonary Vein Isolation 11:15-11:30 Marianna Meo*, Carole Dumas-Pomier, Mélèze Hocini,

Michel Haïssaguerre, Rémi Dubois

68-59 Quantitative Evaluation of Temporal Occurrence Patterns of Paroxysmal Atrial Fibrillation 11:30-11:45 Monika Šimaitytė*, Andrius Petrėnas, Vaidotas Marozas, Justinas Bacevičius, Audrius Aidietis, Leif Sornmo

- 38 -

Tuesday, September 25, 2018 10:15 S44 Special Session: Personalized Medicine Chairs: Pietro Bonizzi and Matthijs Cluitmans Room: 0.5 Paris 69-81 Imaging-Based Simulations for Predicting Sudden Death and Guiding Ablation 10:15-10:45 Natalia Trayanova* 70-400 Personalization of Biomechanical Models for Early Detection of Disease 10:45-11:00 Nick Van Osta, Feddo Kirkels, Aurore Lyon, Tammo Delhaas, Maarten-Jan Cramer, Arco Teske, Joost Lumens*

71-64 Personalisation of Electromechanical Models: Are We There Yet? 11:00-11:15 Nicolas Cedilnik, Tania Bacoyannis, Maxime Sermesant* 72-63 Personalization of Cellular Electrophysiology Models: Utopia? 11:15-11:30 Michael Clerx* 73-403 Personalized Medicine: Discussion 11:30-11:45 Pietro Bonizzi*, Matthijs Cluitmans

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Tuesday, September 25, 2018 12:45 S51 Heart Rate Variability: Applications Chairs: Roberto Sassi and Urban Wiklund Room: 0.8 Rome 74-42 The Heart Rate Variability Multifractality Spectrum and not the Power Spectrum Is Altered in Paraplegic Individuals With Low-Level Lesion 12:45-13:00 Paolo Castiglioni*, Giampiero Merati, Andrea Faini 75-113 Heart Rate Variability Analysis During Weaning From Mechanical Ventilation: Models for Prediction of the Weaning Trial Outcome 13:00-13:15 Vessela Krasteva*, Mikhail Matveev, Irena Jekova, Georgi Georgiev

76-148 Multidomain Short-Term Heart Rate Variability Analysis to Detect Single Night Sleep Deprivation on Drivers 13:15-13:30 Jose Gallardo, Giannina Bellone, Augusto Santini*, Daniel Vigo, Mariano Llamedo Soria

77-243 Dynamical Landscape of Heart Rhythm in Discerning Erratic Rhythm in Elderly People 13:30-13:45 Danuta Makowiec*, Dorota Wejer, Joanna Wdowczyk, Marta Zarczynska-Buchowiecka, Zbigniew Struzik

78-319 Heart Rate Variability Analysis Guided by Respiration in Major Depression Disorder 13:45-14:00 Spyridon Kontaxis*, Michele Orini, Eduardo Gil, Mar Posadas- De Miguel, Maria Luisa Bernal, Jordi Aguiló, Concepción de la Camara, Pablo Laguna, Raquel Bailón

79-369 Heart Rate Variability Analysis of Normal and Intrauterine Growth Restricted Children Using Sample Entropy 14:00-14:15 Taher Biala*, J. Alexandre Lobo marques, Mahmoud Ehnesh, Fernando Schlindwein, Michael Wailoo

- 40 -

Tuesday, September 25, 2018 12:45 S52 Modeling Ion Channels and Cells Chairs: Stefano Severi and Henggui Zhang Room: 0.9 Athens 80-224 The Mechanism Underlying Heart Rate and Pacemaking Activity Decline in Developing Rabbit Sino-Atrial Node 12:45-13:00 Azzah Alghamdi*, Craig P Testrow, Dominic G Whittaker, Henggui Zhang

81-267 Mechanism of Sinus Node Dysfunction in Carriers of the E161K Mutation in the SCN5A Gene 13:00-13:15 Ronald Wilders* 82-304 Development and Validation of an In Silico Rabbit Purkinje Cell Action Potential Model: A Step Towards a Drug Safety Testing Tool 13:15-13:30 Jordi Cano*, Julio Gomis-Tena, Alexander Amberg, Lennart Anger, Vιronique Ballet, Jean-Michel Guillon, Manuel Pastor, Ferran Sanz, Lucia Romero, Javier Saiz

83-92 Computational Mechanistic Investigation of Chronotropic Effects on Murine Sinus Node Cells 13:30-13:45 Benjamin Winkelmann*, Eike Moritz Wόlfers, Callum M. Zgierski-Johnston, Peter Kohl, Jens Timmer, Gunnar Seemann

84-354 Isosbestic Point in Optical Mapping With Di-4-ANBDQPQ Transmembrane Voltage Sensitive Dye 13:45-14:00 Ilija Uzelac*, Flavio Fenton 85-156 Inward Rectifier Current Downregulation Promotes Spontaneous Calcium Release in a Novel Model of Rat Ventricular Electrophysiology 14:00-14:15 Harley Stevenson-Cocks*, Michael Colman, Ed White, Alan Benson

- 41 -

Tuesday, September 25, 2018 12:45 S53 AF Detection and Simulation Chairs: Mark Potse and Gunnar Seemann Room: 0.4 Brussels 86-402 Subclinical Atrial Fibrillation Detection and Relevance (Clinical talk) 12:45-13:15 Pyotr Platonov* 87-34 Acute Morphological Changes in P-Wave Morphology During Pulmonary Vein Isolation in Atrial Fibrillation Patients 13:15-13:30 Ali Gharaviri*, Matthias Zink, Simone Pezzuto, Mark Potse, Stef Zeemering, Rolf Krause, Angelo Auricchio, Ulrich Schotten

88-297 In Silico Model of SK Channel Gating, Temperature Dependence, and Calcium Sensitivity 13:30-13:45 Ilse van Herck*, Bo H. Bentzen, Vincent Seutin, Jussi T. Koivumäki, Mary M. Maleckar, Neil V. Marrion, Andrew G. Edwards

89-291 Stationary and Recurrent Properties of Atrial Fibrillation Conduction Patterns in Goat 13:45-14:00 Arne van Hunnik*, Stef Zeemering, Piotr Podziemski, Giulia Gatta, Sander Verheule, Ulrich Schotten

90-160 Deep Learning for End-to-End Atrial Fibrillation Recurrence Estimation 14:00-14:15 Riddhish Bhalodia*, Anupama Goparaju, Tim Sodergren, Ross Whitaker, Alan Morris, Evgueni Kholmovski, Nassir Marrouche, Joshua Cates, Shireen Elhabian

- 42 -

Tuesday, September 25, 2018 12:45 S54 ECG Processing and Artificial Intelligence Chairs: Peter MacFarlane and Gari Clifford Room: 0.5 Paris 91-108 Supervised Transfer Learning for Personalized Heart Rate Based Epileptic Seizure Detection 12:45-13:00 Thomas De Cooman*, Carolina Varon, Wim Van Paesschen, Sabine Van Huffel

92-174 Cardiac Fibrosis Detection Applying Machine Learning Techniques to Standard 12-Lead ECG 13:00-13:15 Francisco-Manuel Melgarejo-Meseguer*, Francisco-Javier Gimeno-Blanes, Jose Luis Rojo-Alvarez, Mariela Salar-Alcaraz, Juan-Ramón Gimeno-Blanes, Arcadi García-Alberola

93-202 ECG Rhythm Analysis During Manual Chest Compressions Using an Artefact Removal Filter and Random Forest Classifiers 13:15-13:30 Iraia Isasi*, Ali Bahrami Rad, Unai Irusta, Morteza Zabihi, Elisabete Aramendi, Trygve Eftestøl, Jo Kramer-Johansen, Lars Wik

94-327 Premature Ventricular Conduction Detection and Localization From the ECG Using a Neural Network 13:30-13:45 Alexander Vieira Pereira, Peter van Dam, Roger Abächerli* 95-378 Improving Generalization of Deep Models for Cardiac Disease Detection Using Limited Channel ECG 13:45-14:00 Deepta Rajan*, David Beymer, Girish Narayan

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Tuesday, September 25, 2018 14:30 S61 Modeling Ensembles of Cells Chairs: Gunnar Seeman and Andreu Climent Room: 0.8 Rome 96-68 A Heterogeneous Formulation of the Himeno et al. Human Ventricular Myocyte Model for Simulation of Body Surface ECGs 14:30-14:45 Axel Loewe*, María Hernández Mesa, Nicolas Pilia, Stefano Severi, Olaf Doessel

97-188 A Novel Model of the Rabbit Atrial Myocyte for the Study of Ca2+ Mediated Arrhythmia 14:45-15:00 Maxx Holmes*, Alan P Benson, Oleg Aslanidi, Michael A Colman 98-57 Microscopic Simulation of the Cardiac Electrophysiology: A Study of the Influence of Different Gap Junctions Models 15:00-15:15 Pierre-Elliott Bécue*, Mark Potse, Yves Coudière 99-86 In Silico Populations Optimized Based on Optogenetic Recordings Predict Drug Effects in Human-Induced Pluripotent Stem Cell Derived Cardiomyocytes 15:15-15:30 Michelangelo Paci*, Elisa Passini, Aleksandra Klimas, Stefano Severi, Jari Hyttinen, Blanca Rodriguez, Emilia Entcheva

100-356 Insights Into the Mechanisms of Calcium Wave Propagation Failure From a Computational Model of the Rabbit Atrial Cardiomyocyte 15:30-15:45 Marcia Vagos*, Jordi Heijman, Hermenegild Arevalo, Ulrich Schotten, Joakim Sundnes

101-139 Geometric Wavelength for Monitoring Dynamic Changes in Repolarization Caused by Time-Varying Parameters 15:45-16:00 Ariane Saliani, Narendra Shivaraman, Vincent Jacquemet*

- 44 -

Tuesday, September 25, 2018 14:30 S62 Special Session: Physics vs Machine Learning Based Approaches in ECGI Chairs: Linwei Wang and Dana Brooks Room: 0.9 Athens 102-348 A Common-Ground Review of the Potential for Machine Learning Approaches in Electrocardiographic Imaging Based on Probabilistic Graphical Models 14:30-15:00 Jaume Coll-Font*, Linwei Wang, Dana Brooks 103-144 Electrocardiogram Monitoring and Interpretation: From Traditional Machine Learning to Deep Learning, and Their Combination 15:00-15:15 Saman Parvaneh*, Jonathan Rubin 104-69 Combining Biophysical Modeling and Machine Learning to Predict Location of Atrial Ectopic Triggers 15:15-15:30 Eduardo Godoy, Miguel Lozano, Ignacio Garcia-Fernandez, Rafael Sebastian*

105-75 Deep Generative Modeling and Analysis of Cardiac Transmembrane Potential 15:30-15:45 Sandesh Ghimire*, Linwei Wang

- 45 -

Tuesday, September 25, 2018 14:30 S63 Cardiorespiratory Autonomic Iterations Chairs: Laura Burattini and Jesus Lazaro Room: 0.4 Brussels 106-45 PCG-Delineator: an Efficient Algorithm for Automatic Heart Sounds Detection in Fetal Phonocardiography 14:30-14:45 Annachiara Strazza, Agnese Sbrollini*, Valeria di Battista, Rita Ricci, Letizia Trillini, Ilaria Marcantoni, Micaela Morettini, Sandro Fioretti, Laura Burattini

107-9 Fetal Developmental Deviations Reflected in a Functional Autonomic Brain Age Score 14:45-15:00 Dirk Hoyer*, Alexander Schmidt, Uwe Schneider, Kathleen Gustafson

108-54 Pilot Study on Electrocardiogram Derived Respiratory Rate Using a Wearable Armband 15:00-15:15 Jesus Lazaro*, Raquel Bailón, Eduardo Gil, Yeonsik Noh, Pablo Laguna, Ki Chon

109-310 Identification of Fetal Cardiac Timing Events by Swarm Decomposition of Doppler Cardiogram Signal 15:15-15:30 Saeed Alnuaimi*, Shihab Jimaa, Yoshitaka Kimura, Georgios Apostolidis, Leontios Hadjileontiadis, Ahsan Khandoker

110-26 Autonomic, Cardiovascular, and Respiratory Responses to Hyperglycemic Stimulus in Healthy Subjects 15:30-15:45 Salvador Carrasco-Sosa, Alejandra Guillén-Mandujano* 111-122 Early Detection of Cheyne-Stokes Breathing via ECG- Derived Respiration in Patients With Severe Heart Failure: A Pilot Study 15:45-16:00 Pauline Guyot*, Bruno Chenuel, El-Hadi Djermoune, Thierry Bastogne

- 46 -

Tuesday, September 25, 2018 14:30 S64 ECG Processing of Ventricular Repolarization Chairs: Jean-Philippe Couderc and Luca Mainardi Room: 0.5 Paris 112-67 A Novel Electrocardiograph for Analysis of Ventricular Repolarisation 14:30-14:45 Laura Cooney*, Peter Macfarlane 113-43 T-Wave Alternans in Partial Epileptic Patients 14:45-15:00 Ilaria Marcantoni, Valeria Cerquetti, Valentina Cotechini, Maeva Lattanzi, Agnese Sbrollini, Micaela Morettini, Laura Burattini*

114-302 Intrauterine Growth Restriction Induced ECG Morphological Differences Measured in Adulthood 15:00-15:15 Nuria Ortigosa*, Merida Rodriguez-Lopez, Raquel Bailón, Alvaro Sepulveda, Fatima Crispi, Pablo Laguna

115-180 Theoretical and Empirical Estimates of V-index Variability 15:15-15:30 Massimo W Rivolta*, Luca Mainardi, Roberto Sassi 116-53 Multiscale Complexity Analysis of Short QT Interval Variability Series Stratifies the Arrhythmic Risk of Long QT Syndrome Type 1 Patients 15:30-15:45 Vlasta Bari*, Beatrice De Maria, Giulia Girardengo, Emanuele Vaini, Beatrice Cairo, Lia Crotti, Paul Brink, Peter Schwartz, Alberto Porta

117-19 An Instantaneous Measure of ECG Signal Quality 15:45-16:00 Sasan Yazdani*, Jean-Marc Vesin

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Tuesday, September 25, 2018 16:00 P71 Modeling Ion Channels, Cells and Fetal Signals Room: Main Lobby 118-32 A Novel Model of Electrical Action Potentials of Teleost Fish Ventricular Myocytes Hamsa Naser*, Dominic G Whittaker, Holly Shiels, Mark Boyett, Henggui Zhang

119-65 Mechano-Electric Feedbacks in a New Model of the Excitation-Contraction Coupling in Human Cardiomyocytes Nathalie Balakina-Vikulova*, Olga Solovyova, Alexander Panfilov, Leonid Katsnelson

120-140 Fibroblasts Induce Calcium Alternans When Coupled to Cardiomyocytes: A Simulation Study Maria Teresa Mora, Albert Dasi, Javier Saiz*, Beatriz Trenor, Jose M Ferrero

121-62 New Mathematical Model of Electromechanical Coupling in Rat Cardiomyocytes Leonid Katsnelson*, Pavel Konovalov, Olga Solovyova 122-103 Simultaneous Electrical and Fluorescence Recording of HL-1 Cells Electrical Activity in Response to Extracellular Calcium Stimulation Ondrej Svoboda, Larisa Baiazitova*, Vratislav Cmiel, Josef Skopalik, Zdenka Fohlerova, Jaromir Hubalek, Ivo Provaznik

123-170 Effects of CaMKII Regulation on Atrial Action Potential Under Oxidative Stress Condition Haibo Sui, Qince Li*, Kuanquan Wang, Funebi Francis Ijebu, Yongfeng Yuan, Henggui Zhang

124-184 Computational Modeling of Cardiac Metabolism in Atrial Myocytes Funebi Francis Ijebu, Qince Li*, Kuanquan Wang, Haibo Sui, Lufang Zhou, Henggui Zhang

125-323 RyRs Coupling Causes a Calcium Leak in Cardiac Cell Alexander Ryvkin*, Nikita Markov

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126-333 Optimization of the O’Hara-Rudy Model of Human Ventricular Action Potential With Respect to Electrolyte Concentrations and Rate Dependence Chiara Bartolucci*, Elisa Passini, Stefano Severi 127-193 Role of Funny Current in Biological Pacemaker Based on Human Ventricular Model Yacong Li*, Kuanquan Wang, Qince Li, Xiangyun Bai, Henggui Zhang

128-367 State-Space Detection of the Impulse Response Gain and Delay From Intrapartum Cardiotocography Philip Warrick*, Emily Hamilton 129-228 Proliferation of Fibroblast Modulates the Action Potential Duration Dispersion: An Atrial Fibrosis Model Using Fractional Diffusion Juan P Ugarte*, Catalina Tobon, Laura C Palacio, Henry Andrade-Caicedo, Javier Saiz

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Tuesday, September 25, 2018 16:00 P72 Modeling Drug Effects and Mutations Room: Main Lobby 130-58 Sulfur Dioxide Effects on Human Atrial Action Potential. In Silico Study Catalina Tobon, Juan P Ugarte*, Laura C Palacio, Javier Saiz 131-124 Carbon Monoxide Effects on Electrophysiological Mechanisms of Ventricular Arrhythmogenesis Moza Al-Owais, Arun Holden*, Chris Peers, Derek Steele, Alan Benson

132-166 Effects of the β-Adrenoceptor Blocker Carvedilol in Short QT Syndrome Caused by N588K Mutation in hERG: A Simulation Study Cunjin Luo*, Linghua Li, Tong Liu, Kuanquan Wang, Xiangyun Bai, Ying He, Henggui Zhang

133-48 In Silico Investigation of the Functional Impact of SCN10A Mutations in Human Atrial Cells Inas A Al Nemi*, Haibo Ni, Henggui Zhang 134-133 Modelling the Effects of Propafenone on Human Atrial Patho-Electrophysiology Associated With hERG-Linked Short QT Syndrome Dominic G Whittaker*, Jules C Hancox, Henggui Zhang 135-213 Impact of Two Different CaV 1.2 Mutations on Cardiac Action Potential and Calcium Content Gunnar Seemann*, Sebastian Kummer, Susanne Rinné, Niels Decher

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Tuesday, September 25, 2018 16:00 P73 Mechanisms of Reentry and Fibrillation Room: Main Lobby 136-130 Effects of Atrial Fibrillation on the Coronary Flow at Different Heart Rates: A Computational Approach Caterina Gallo*, Stefania Scarsoglio, Luca Ridolfi 137-298 Parameter Sensitivity Analysis to Predict Action Potential Duration Alternans in Cardiac Electrophysiology Simulation Nida Dusturia*, Ki Moo Lim 138-225 The Effects of Nonischemic Fibrosis Scar Morphology on Mechanisms of Reentry Gabriel Balaban*, Caroline Mendoca Costa, Brian Halliday, Bradley Porter, Wenjai Bai, Gernot Plank, Christopher Rinaldi, Daniel Rueckert, Sanjay K. Prasad, Martin Bishop

139-340 Predicting and Observing Chaotic Dynamics in Excitable Media Using Machine Learning Ulrich Parlitz*, Roland Zimmermann, Sebastian Herzog, Jonas Isensee, George Datseris

140-233 Particle Filter Tracking of Complex Stochastic Systems Applied to In Silico Wavefront Propagation Gonzalo Ricardo Ríos-Muñoz*, Antonio Artés-Rodríguez,

Joaquín Míguez

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Tuesday, September 25, 2018 16:00 P74 Whole Heart Modeling Room: Main Lobby 141-183 Patient-Tailored In Silico 3D Simulations and Models From Electroanatomical Maps of the Left Atrium Gonzalo Ricardo Ríos-Muñoz*, Sara Rocher, Antonio Artés-

Rodríguez, Ángel Arenal, Javier Saiz, Carlos Sánchez

142-10 A Multiscale Intracranial Pressure Signal Simulator Federico Wadehn*, David-Jule Mack, Emanuela Keller, Thomas Heldt

143-96 A Support Vector Regression-Based Data-Driven Leaflet Modeling Approach for Personalized Aortic Valve Prosthesis Development Jannis Hagenah*, Tizian Evers, Michael Scharfschwerdt, Achim Schweikard, Floris Ernst

144-47 Impact of Limits in Pathways Between Sinoatrial Node and Atrium on Heart Rhythm by Timed Automata Model Danuta Makowiec*, Zbigniew Struzik 145-114 Universal Ventricular Coordinates: A New Way to Transfer Purkinje Networks Between Meshes Julien Bouyssier*, Jason Bayer, Edward Vigmond 146-223 A Study on the Characteristics Influencing the Pressure in the Inlet of a One-Dimensional Model of Arterial Structure Shima Abdullateef*, Jorge Mariscal-Harana, Jordi Alastruey, Ashraf Khir

147-285 Heart Block in the Athlete – Role of Ion Channel Remodelling as Studied Using a One-Dimensional Computational Model of the Atrioventricular Node Jue Li*, Pietro Mesirca, Alicia D’Souza, Shu Nakao, Charlotte Cox, Jules Hancox, Matteo Mangoni, Mark Boyett 148-55 Optical Mapping Could Reveal Two-Dimensional Morphology of Atrioventricular Electrical Insulation in the Foetal Avian Heart Veronika Olejnickova*, Oto Janousek, Marina Ronzhina, Jakub Hejc, Alena Kvasilova, Eva Zabrodska, David Sedmera

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Tuesday, September 25, 2018 16:00 P75 Analysis and Mapping in Arrhythmia Room: Main Lobby 149-172 In Silico Comparison of Phase Maps Based on Action Potential and Extracellular Potential Konstantin Ushenin*, Artem Razumov, Vitaly Kalinin, Olga Solovyova

150-296 Trajectories of the Single Moving Equivalent Dipole in Subjects With Left Fascicular Block Vito Starc*, Cees A. Swenne 151-384 Validation of Noninvasive Electrophysiological Mapping Accuracy Using Endocardial Pacing With Three- Dimensional Nonfluoroscopic Electroanatomic Mapping Margarita Budanova*, Mikhail Chmelevsky, Stepan Zubarev, Danila Potyagaylo, Boris Rudic, Erol Tulumen, Martin Borggrefe 152-290 QRS Complex Classifier for Personalized Healthcare Applications Rohit Hadia*, Dewar Finlay, Daniel Guldenring, Ghalib Muhammad Waqas Janjua, Raymond Bond, James McLaughlin

153-109 Unobtrusive Contactless Cardiac Monitoring for Telemedicine and Ambient Assisted Living Andres Lorenzo Bleda*, Rafael Maestre Ferriz, Arcadio Garcia Alberola

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Tuesday, September 25, 2018 16:00 P76 Ischemia and Infarct Analysis with ECG and Imaging Room: Main Lobby 154-85 Detection of ST-Segment Variation in ECG Using Transfer Entropy Ilya Potapov*, Esa Räsänen 155-128 Automatic Segmentation of Myocardial Infarction in Rats Subjected to Regional Ischemia Roman Jakubicek, Jiri Chmelik*, Jan Neckar, Radim Kolar 156-51 High Frequency QRS Analysis From Orthogonal Leads Josef Halamek*, Pavel Leinveber, Marek Malik, Filip Plesinger, Magdalena Matejkova, Jolana Lipoldova, Pavel Jurak

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Tuesday, September 25, 2018 16:00 P77 New Approaches and Applications of ECGI Room: Main Lobby 157-381 Evaluation of ECG Imaging Accuracy for Biventricular Pacings in Patients With a Cardiac Resynchronization Therapy Device Danila Potyagaylo*, Mikhail Chmelevsky, Stepan Zubarev, Margarita Budanova, Vitaly Kalinin, Alexander Kalinin, Dmitry Lebedev

158-324 Forcing Transmembrane Voltages to Decrease Slowly: A Temporal Regularization for ECG Imaging Steffen Schuler*, Axel Loewe, Olaf Doessel 159-105 Body-Surface Mapping Using High-Frequency ECG to Characterize Electrical Activation Delay Petr Andrla*, Pavel Leinveber, Uyên Châu Nguyên, Ivo Viscor, Filip Plesinger, Frits Prinzen, Josef Halamek, Magdalena Matejkova, Pavel Jurak

160-314 A Learning Based Statistical Approach for Combining Multiple Measurements in Electrocardiographic Imaging Taha Erenler*, Yesim Serinagaoglu Dogrusoz 161-315 Impact of Signal Preprocessing on the Inverse Localization of the Origin of Ventricular Tachycardia Jana Svehlikova*, Jan Zelinka, Yesim Serinagaoglu Dogrusoz, Wilson Good, Milan Tysler, Laura Bear

162-265 Automatic Generation of Biventricular Models of Cardiac Electrophysiology for Patient Specific Personalization Using Noninvasive Recordings Karli Gillette*, Anton Prassl, Jason Bayer, Edward Vigmond, Aurel Neic, Gernot Plank

163-101 T-Wave Alternans Analysis With Electrocardiographic Imaging Jose Luis Rojo-Alvarez*, Rebeca Goya-Esteban, Sergio Muñoz-

Romero, Arcadi García-Alberola, Francisco-Manuel Melgarejo-

Meseguer, Manuel Blanco-Velasco

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164-157 ECG Imaging of Ventricular Ischemia Lesions Vinay Kara*, Haibo Ni, Erick Andres Perez Alday, Henggui Zhang 165-182 Electrocardiographic Imaging of Atrial Fibrillation Detects Sites of Acute Termination After Rotor Ablation Miguel Rodrigo*, Andreu M. Climent, Ismael Hernandez- Romero, Tina Baykaner, Wouter-Jan Rappel, Maria S Guillem, Felipe Atienza, Sanjiv M Narayan

166-344 The Heart Recording Conditions Impacts on the Assessment of the Electrocardiography Imaging Inverse Solution Amel Karoui*, Laura Baer, Pauline Migerditichan, Mostafa Bendahmane, Nejib Zemzemi

167-347 Comparison of Left Ventricle Late Activation Zones Determined Using Noninvasive Electrophysiological Mapping With Sequential CT and MRI Stepan Zubarev*, Mikhail Chmelevsky, Danila Potyagaylo, Margarita Budanova, Sergey Rud, Anton Ryzhkov, Dmitriy Lebedev

168-239 Quantitative Analysis of Rotor Distribution in Atrial Fibrillation via Noninvasive Electrocardiographic Imaging Roland Sanford*, Jonathan Chrispin, Saman Nazarian, Linwei Wang

169-259 An Adaptive Laplacian Based Interpolation Algorithm for Noise Reduction in Body Surface Potential Maps Ali Rababah*, Dewar Finlay, Daniel Guldenring, Raymond Bond, James McLaughin

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Tuesday, September 25, 2018 16:00 P78 ECG Waveform Analysis Room: Main Lobby 170-287 Correlation and Clustering Properties of Premature Ventricular Contractions in 24-Hour ECGs of Postinfarction Patients Annette Witt* 171-151 Invariant Mean Electrical Axis in Electrocardiogram Kjell Le*, Trygve Eftestøl, Kjersti Engan, Øyunn Kleiven, Stein Ørn

172-46 Integrating the Exercise and Environmental Data into a Digital ECG Structure by Watermarking Technique Piotr Augustyniak* 173-375 Detecting Flutter Waves in the Electrocardiogram Using Generalized Likelihood Ratio Test Muhammad Haziq Kamarul Azman*, Olivier Meste, Kushsairy Kadir

174-379 Versatile Detector of Pseudo Periodic Patterns Augusto Santini*, Emiliano Diez, Mariano Llamedo Soria 175-95 Spectral-Based Analysis of Progressive Dynamical Changes in the Fetal Heart Rate Signal During Labor by Using Empirical Mode Decomposition Patricio Fuentealba*, Alfredo Illanes, Frank Ortmeier

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Tuesday, September 25, 2018 16:00 P79 ECG Heterogeneity Room: Main Lobby 176-162 The Reproducibility of Global Electrical Heterogeneity ECG Measurements Erick Andres Perez Alday*, Christopher Hamilton, Annabel Lipershi, Jose Manuel Monroy Trujillo, Michelle Estrella, Stephen M sozio, Bernard Jaar, Rulan Parekh, Larisa Tereshchenko

177-177 T-Wave Morphology Restitution in Chronic Heart Failure Patients With Atrial Fibrillation Flavio Palmieri*, Juan Pablo Martínez, Laura Burattini, Julia

Ramírez

178-277 ECG-Based Monitoring of Electrolyte Fluctuations During the Long Interdialytic Interval Ana Rodrigues*, Andrius Petrėnas, Neda Kušleikaitė-Pere, Pablo Laguna, Vaidotas Marozas

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Tuesday, September 25, 2018 16:00 P7A Wavelet Based Analysis of ECG Room: Main Lobby 179-336 Wavelet Based Algorithm for the Automatic Detection of Activations in Intracardiac Records in the Presence of Supraventricular Tachyarrhythmia Jaime Yagόe-Mayans, Francisco Castells, Javier Moreno, Jose Millet*, Raquel Cervigσn

180-200 An Efficient Algorithm Based on Wavelet Transform to Reduce Powerline Noise From Electrocardiograms Juan Ródenas, Manuel García, José J Rieta, Raul Alcaraz*

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Tuesday, September 25, 2018 16:00 P7B ECG Fiducial Detection Room: Main Lobby 181-141 Performance Analysis of T-Wave-Offset Detection Algorithms on Patients With Cardiac Diseases Deborah Nairn, Pietro Bonizzi, Joël Karel*, Alfonso Aranda 182-123 R-Peak Detection in Holter ECG Signals Using Non- Negative Matrix Factorization Pauline Guyot*, Pascal Voiriot, El-Hadi Djermoune, Stéphane Papelier, Céline Lessard, Mathieu Felices, Thierry Bastogne

183-155 Multidimensional Vectorcardiography. Is More Better? Alfonso Aranda*, Pietro Bonizzi, Joel Karel, Ralf Peeters 184-82 A Multilead QRS Complex Detection Method on 12-Lead Electrocardiogram Signals Wei Zhao*, Yanwu Xu, Cong Yan, Jing Hu, Jia Dongya, Hongmei Wang, Tianyuan You

185-281 Analysis of the Observation Sequence Duration of Hidden Markov Models for QRS Complex Detection in Single-Lead ECG Recordings Nelson Monroy*, Miguel Altuve 186-52 Real-Time Detection of Pace Pulses in a Single Lead ECG Irena Jekova*, Serafim Tabakov, Ivo Iliev, Valentin Tsibulko, Krasimira Kostikova

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Tuesday, September 25, 2018 16:00 P7C Denoising ECT Room: Main Lobby 187-100 Detection of Unicolor ECG Electrode Reversals in Standard 12-Lead ECG Irena Jekova*, Remo Leber, Vessela Krasteva, Ramun Schmid 188-198 Kalman Filter Based Electromyographic Signal Suppression of Real-Time ECG Signal Meng Chen*, Yizhou Zhong, Huaiyu Zhu, Yun Pan 189-165 Global Electrical Heterogeneity: Mechanisms and Clinical Significance Larisa Tereshchenko* 190-209 A Novel Algorithm for Full-Automatic Multipurpose ECG Delineation Antoun Khawaja* 191-229 A Novel Algorithm for Full-Automatic ECG Interpretation and Diagnostics Antoun Khawaja* 192-231 Variational Mode Decomposition Features for Heartbeat Classification Amalia Villa Gσmez*, Sibasankar Padhy, Rik Willems, Sabine Van Huffel, Carolina Varon

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Tuesday, September 25, 2018 16:00 P7D ECG Mapping Room: Main Lobby 193-132 Validation of Activation Recovery Interval in Structurally Normal Human Ventricles by Optical Mapping Peter Langfield*, Josselin Duchateau, Richard Walton, Frederic Sacher, Julien Rogier, Louis Labrousse, Fabien Brette, Meleze Hocini, Michel Haissaguerre, Olivier Bernus, Edward Vigmond 194-149 Action Potential Modelling in Isolated Rat Hearts During Hypokalemia Mariano Llamedo Soria, Augusto Santini*, Emiliano Diez 195-286 Sequential Electro-Anatomical Mapping Methodology and Preliminary Results for Reentry Vulnerability Index Estimation Michele Orini*, Ben Hanson, Peter Taggart, Fernando Campos, Jaswinder Gill, Martin Bishop, Pier Lambiase

196-383 Testing a Simple Model of the Unipolar Electrogram in the Intact Human Heart and Examples of Applications Michele Orini*, Peter Taggart, Pier Lambiase 197-345 Evaluation of Multilead ECG Markers to Track Changes in Dispersion of Ventricular Repolarization in the Intact Human Heart Michele Orini*, Neil Srinivasan, Peter Taggart, Pier Lambiase

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Wednesday, September 26, 2018 8:30 S81 Modeling Arrhythmias and Defibrillation Chairs: Ed Vigmond and Natalia Trayanova Room: 0.8 Rome 198-118 Determining Surface Stimulation Parameters With Computational Cardiac Electrophysiology to Defibrillate Human Ventricles 8:30-8:45 Angel Moreno*, Richard Walton, Claudia E. Hawks, Olivier Bernus, Edward Vigmond, Jason Bayer

199-131 Role of Cardiac Microstructure Variability on Ventricular Arrhythmogenesis 8:45-9:00 Dominic G Whittaker*, Alan P Benson, Irvin Teh, Jurgen E Schneider, Michael A Colman

200-385 Phase Space Approach in Quantification of Arrhythmia Induction Caused by Potassium Heterogeneities in Isolated Rabbit Hearts 9:00-9:15 Ilija Uzelac*, Flavio Fenton 201-206 A Multiscale Computational Model of Calcium-Mediated Ectopy in the Human Postinfarction Heart 9:15-9:30 Fernando Campos*, Joao F. Fernandes, Yohannes Shiferaw, Titus Kuehne, Martin Bishop, Gernot Plank

202-390 Diastolic-Interval-Based Control as a Method for Preventing Cardiac Tachyarrhythmias 9:30-9:45 Niels Otani* 203-334 Features of Chaotic Transients in Excitable Media Modeling Cardiac Arrhythmias 9:45-10:00 Ulrich Parlitz*, Thomas Lilienkamp

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Wednesday, September 26, 2018 8:30 S82 Cardiac Autonomic Iterations Chairs: Alejandra Guillen and Ivo Provaznik Room: 0.9 Athens 204-171 Asymmetry Assessment of Cardiac and Sympathetic Arms of the Baroreflex 8:30-8:45 Beatrice De Maria*, Vlasta Bari, Beatrice Cairo, Emanuele Vaini, Elisabeth Lambert, Murray Esler, Mathias Baumert, Sergio Cerutti, Laura Dalla Vecchia, Alberto Porta

205-358 Microgravity Exposure Alters Sympathetic Modulation of Ventricular Repolarization Quantified from the ECG via Periodic Repolarization Dynamics 8:45-9:00 Saúl Palacios*, Enrico Caiani, Juan Pablo Martínez, Esther

Pueyo 206-282 ECG-Derived Sympathetic and Parasympathetic Nervous System Dynamics: A Congestive Heart Failure Study 9:00-9:15 Gaetano Valenza*, Luca Citi, Philip Saul, Riccardo Barbieri 207-25 Effects of Two Types of Linearly Increased Isometric Exercise on Instantaneous Baroreflex and Respiratory Sinus Arrhythmia Sensitivities Computed by Alpha Index 9:15-9:30 Alejandra Guillén-Mandujano*, Salvador Carrasco-Sosa 208-273 Relationship Between Blood Pressure and Heart Rate Circadian Rhythms in Normotensive and Hypertensive Subjects 9:30-9:45 Giulia Silveri*, Lorenzo Pascazio, Agostino Accardo 209-61 Analysis of Linear and Nonlinear Central- Cardiorespiratory Coupling Pathways in Healthy Subjects 9:45-10:00 Steffen Schulz*, Aniol Serra Juhι, Beatriz Giraldo, Jens Haueisen, Karl-Juergen Baer, Andreas Voss

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Wednesday, September 26, 2018 8:30 S83 Challenge I Chairs: Gari Clifford and Philip de Chazal Room: 0.4 Brussels 210-49 You Snooze, You Win: The PhysioNet/Computing in Cardiology Challenge 2018 8:30-8:45 Gari Clifford*, Benjamin Moody, Mohammad Ghassemi, Haoqi Sun, Brandon Westover

211-332 Automated Recognition of Sleep Arousal Using Multimodal and Personalized Deep Ensembles of Neural Networks 8:45-9:00 Andrea Patane*, Shadi Ghiasi, Enzo Pasquale Scilingo, Marta Kwiatkowska

212-252 Automatic Scoring of Non-Apnoea Arousals Using the Polysomnogram 9:00-9:15 Nadi Sadr*, Asghar Tabatabaei Balaei, Philip de Chazal 213-232 Automated Detection of Sleep Arousals From Polysomnography Data Using a Dense Convolutional Neural Network 9:15-9:30 Matthew Howe-Patterson, Bahareh Pourbabaee* 214-284 Evaluating Convolutional and Recurrent Neural Network Architectures for Arousal Detection 9:30-9:45 Ali Shoeb*, Niranjan Sridhar 215-247 Using Auxiliary Loss to Improve Sleep Arousal Detection with Neural Network 9:45-10:00 Bálint Varga, Márton Görög, Péter Hajas*

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Wednesday, September 26, 2018 8:30 S84 ECG Processing of Ventricular Repolarization Chairs: Filip Plesinger and John Wang Room: 0.5 Paris 216-30 Detecting Strict Left Bundle Branch Block From 12-Lead Electrocardiogram Using Support Vector Machine Classification and Derivative Analysis 8:30-8:45 Nipun Perera*, Chathuri Daluwatte 217-204 An Accurate Shock/No-Shock Decision Algorithm for Use During Piston-Driven Chest Compressions 8:45-9:00 Iraia Isasi*, Unai Irusta, Elisabete Aramendi, Unai Ayala, Erik

Alonso, Jo Kramer-Johansen, Trygve Eftestøl

218-216 Identification of Strict Left Bundle Branch Block, Using a Moving Dipole Model 9:00-9:15 Werner Bystricky* 219-292 Deep Learning Based QRS Multilead Delineator in Electrocardiogram Signals 9:15-9:30 Julià Camps*, Blanca Rodriguez, Ana Minchole 220-99 Serial ECG Analysis: Absolute Rather than Signed Changes in the Spatial QRS-T Angle Should Be Used to Detect Emerging Cardiac Pathology 9:30-9:45 Agnese Sbrollini*, Marjolein de Jongh, C. Cato ter Haar, Roderick W Treskes, Sumche Man, Laura Burattini, Cees A. Swenne

221-154 A Wavelet-Based Approach for Automatic Diagnosis of Strict Left Bundle Branch Block 9:45-10:00 Alba Martin*, Juan Pablo Martínez

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Wednesday, September 26, 2018 10:15 S91 ECGI in Clinical Applications Chairs: Maria Guillem and Laura Baer Room: 0.8 Rome 222-325 Personalized Computational Framework to Study Arrhythmia Mechanisms on Top of ECG Image-Detected Substrate 10:15-10:30 Matthijs Cluitmans*, Éric Lluch, Hernán Morales, Jordi

Heijman, Paul Volders

223-303 Noninvasive Electrocardiographic Imaging of Scar- Related Ventricular Tachycardia: Association With Magnetic Resonance Scar Imaging 10:30-10:45 Omar Gharbia, Susumu Tao, Albert C. Lardo, Henry Halperin, Linwei Wang*

224-387 Clinical Validation of ECG Image Epi-Endocardial Mapping Accuracy: Single Center Single-Blind Cross- Sectional Study 10:45-11:00 Mikhail Chmelevsky*, Margarita Budanova, Stepan Zubarev, Danila Potyagaylo, Tatiana Treshkur, Dmitry Lebedev

225-311 Complete-Chamber Conduction Velocity Estimation During Arrhythmias 11:00-11:15 Ismael Hernández-Romero*, Alejandro Liberos, Miguel

Rodrigo, Carlos Figuera, Maria S Guillem, Francisco Fernández-

Avilés, Felipe Atienza, Andreu M. Climent

226-185 Automatic Location of the Atrial Anatomy Under Cumulative Spatial Artifacts Based on ECG Imaging 11:15-11:30 Victor Gisbert, Alejandro Liberos, Ismael Hernandez-Romero, Andreu M. Climent, Felipe Atienza, Maria S Guillem, Miguel Rodrigo*

227-283 Early Results on the Utilisation of ECG-Imaging During Catheter Ablation Procedures for Prediction of Sites of Earliest Activation During Re-entrant Ventricular Tachycardia 11:30-11:45 Michele Orini*, Adam Graham, Mehul Dhinoja, Ross Hunter, Richard Schilling, Anthony Chow, Peter Taggart, Pier Lambiase

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Wednesday, September 26, 2018 10:15 S92 Cardiac Arrest & Resuscitation Chairs: Dewar Finlay and Roger Abacherli Room: 0.9 Athens 228-93 Deep Learning for Pulse Detection in Out-of-Hospital Cardiac Arrest Using the ECG 10:15-10:30 Andoni Elola*, Elisabete Aramendi, Unai Irusta, Artzai Picσn, Erik Alonso, Pamela Owens, Ahamed Idris

229-159 Comparison of Pediatric and Adult ECG Rhythm Analysis by Automated External Defibrillators During Out-of- Hospital Cardiac Arrest 10:30-10:45 Vessela Krasteva*, Sarah Ménétré, Irena Jekova, Todor

Stoyanov, Daniel Jost, Benoit Frattini, Sabine Lemoine,

Frédéric Lemoine, Vincent Thomas, Jean-Philippe Didon

230-107 A Method to Suppress Chest Compression Artifact Enhancing Capnography-Based Ventilation Guidance During Cardiopulmonary Resuscitation 10:45-11:00 Mikel Leturiondo*, Jose Julio Gutierrez, Sofia Ruiz de Gauna, Jesus Ruiz, Luis Alberto Leturiondo, James Knox Russell, Mohamud Daya

231-97 Finger Photoplethysmography to Monitor Chest Compression Rate During Out-of-Hospital Cardiac Arrest 11:00-11:15 Andoni Elola*, Jon Urteaga, Elisabete Aramendi, Unai Irusta, Erik Alonso, Mohamud Daya, Pamela Owens, Ahamed Idris

232-116 CPR Guideline Chest Compression Depths May Exceed Requirements for Optimal Physiological Response 11:15-11:30 Olibhéar McAlister*, Daniel Guldenring, Dewar Finlay, Raymond Bond, Hannah Torney, Ben McCartney, Laura Davis, Paul Crawford, Adam Harvey

233-246 Estimation of Chest Compression Rate and Detection of Hands-off Intervals During Resuscitation With Automated External Defibrillators 11:30-11:45 Jesus Ruiz, Sofia Ruiz de Gauna*, Pablo Bahillo, Digna María

González-Otero, Purificación Saiz, Daniel Alonso, Karlos

Ibarguren

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Wednesday, September 26, 2018 10:15 S93 Challenge II Chairs: Gari Clifford and Philip de Chazal Room: 0.4 Brussels 234-401 Physionet Challenge 2018 - Overview 10:15-10:30 Gari Clifford* 235-257 Automatic Sleep Arousal Detection Using Multimodal Biosignal Analysis 10:30-10:45 Ali Bahrami Rad*, Morteza Zabihi, Simo Särkkä, Serkan

Kiranyaz, Aggelos K. Katsaggelos, Moncef Gabbouj

236-40 Automated Sleep Arousal Detection Based on EEG Envelograms 10:45-11:00 Filip Plesinger*, Petr Nejedly, Ivo Viscor, Petr Andrla, Josef Halamek, Pavel Jurak

237-89 Detection of Respiratory Effort Related Arousals Using Hidden Markov Model and Random Decision Forest 11:00-11:15 János Szalma*, András Bánhalmi, Vilmos Bilicki 238-60 Identification of Arousals With Deep Neural Networks Using Different Physiological Signals 11:15-11:30 Runnan He*, Kuanquan Wang, Yang Liu, Na Zhao, Yongfeng Yuan, Qince Li, Henggui Zhang

239-380 Detection of Sleep Arousals Based on Spatiotemporal Features 11:30-11:45 Muhammad Bilal, Muhammad Rizwan Khan, Hassan Aqeel Khan*, Maham Qureshi, Sajid Saleem, Awais Mehmood Kamboh

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Wednesday, September 26, 2018 10:15 S94 ECG Processing and Arrhythmias Chairs: Paul Rubel and Pyotr Platonov Room: 0.5 Paris 240-33 Mean Temporal Spatial Isochrones as Marker for Activation Delay in Patients With Arrhythmogenic Cardiomyopathy 10:15-10:30 Rob Roudijk*, Peter Loh, Eelco van Dam, Peter van Dam 241-120 A Hidden Markov Model Approach for Ventricular Fibrillation Detection 10:30-10:45 Borja Altamira, Erik Alonso*, Unai Irusta, Elisabete Aramendi, Mohamud Daya

242-153 A Comparison of ECG Waveform Features for the Classification of Normal and Abnormal Heartbeats 10:45-11:00 Emilien Le Flahat*, Jean-Christophe Billard, Eric Plourde 243-355 Localizing Atrial Flutter Circuit Using Variability in the Vectorcardiographic Loop Parameters 11:00-11:15 Muhammad Haziq Kamarul Azman*, Olivier Meste, Kushsairy Kadir, Decebal Gabriel Latcu

244-163 Real-Time Fusion of ECG and SpO2 Signals to Reduce False Alarms 11:15-11:30 Jianwei Su, Sanchao Liu, Zehui Sun, Bailei Sun, Wenyu Ye, Cadathur Rajagopalan*, Xianliang He

245-91 Respiratory Sinus Arrhythmia in Apnea Patients With Apnea Associated Comorbidities 11:30-11:45 John Morales*, Margot Deviaene, Javier Milagro, Dries Testelmans, Bertien Buyse, Raquel Bailσn, Rik Willems, Sabine Van Huffel, Carolina Varon

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Wednesday, September 26, 2018 12:15 PA1 Challenge Posters Room: Main Lobby 246-50 Effectiveness of a Convolutional Neural Network in Sleep Arousal Classification Using Multiple Physiological Signals Yinghua Shen* 247-126 Detecting Cortical Arousals From Biological Signals Using Signal Processing and Neural Networks Guðni Fannar Kristjansson, Heiðar Már Þráinsson, Hanna

Ragnarsdóttir, Bragi Marinósson, Eysteinn Gunnlaugsson,

Eysteinn Finnsson, Sigurður Ægir Jónsson, Halla Helgadóttir,

Jón Skírnir Ágústsson*

248-197 Non-Apnea Arousal Detection Using Multiple-Biological Signals With Time and Frequency Domain Features Fatih Caglar, Emin Argun Oral*, Ibrahim Yucel Ozbek 249-104 Detecting Respiratory Effort-Related Arousals in Polysomnographic Data Using Intelligent Pattern Recognition Sven Schellenberger*, Kilin Shi, Melanie Mai, Jan Philipp Wiedemann, Tobias Steigleder, Björn Eskofier, Robert Weigel, Alexander Kölpin

250-152 Deep Multimodal Framework Augmented With Feature- Based Approach for Automatic Detection of Arousals During Sleep Saman Parvaneh*, Jonathan Rubin, Ali Samadani, Adi Prakash, Gajendra Katuwal

251-226 Automatic Detection of Respiratory Effort Related Arousals From Polysomnographic Recordings Ivan Lazić*, Nikša Jakovljević, Danica Despotović, Tatjana Lončar-Turukalo

252-230 Knowledge Extraction of Physiological Signals Based on Deep Neural Networks: Arousals Case Edwar Macias Toro*, Antoni Morell, Javier Serrano, Jose Lopez Vicario 253-83 Sleep Arousal Detection Using End-to-End Deep Learning Method Based on Raw Multi-physiological Signals Haoqi Li*, Qineng Cao, Yizhou Zhong, Yun Pan

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254-245 SleepTight: Identifying Sleep Arousals Using Inter- and Intrarelation of Multimodal Signals Tanuka Bhattacharjee*, Deepan Das, Anirban Dutta Choudhury, Rohan Banerjee

255-217 Sleep Arousal Classification Using Autoencoded Physiological Signals and Long Short-Term Memory Vykintas Maknickas*, Algirdas Maknickas 256-242 Automatic Sleep Arousal Identification From Physiological Waveforms Using Deep Learning Daniel Miller, Andrew Ward, Nicholas Bambos* 257-264 Identification of Sleep Arousal From Physiological Signals Using Machine Learning Classification Algorithms Vinodhini Ranganathan*, Abijeet Waghmare, Uma Maheshwari Krishnaswamy, Tony Raj

258-256 Application of Recurrent Neural Network for the Prediction of Target Non-Apneic Arousal Regions in Physiological Signals Naimahmed Nesaragi, Shubha Majumder, Ashish Sharma, Kouhyar Tavakolian*, Shivnarayan Patidar

259-349 Bayesian Optimization and Stochastic Weight Averaging for LSTM Sleep Arousal Detection Sandya Subramanian*, Leon Chlon, Shubham Chamadia, Sourish Chakravarty

260-371 Deep Learning with Convolutional Neural Networks Sleep Arousal Detection Jia Dongya*, shengfeng yu, Cong Yan, Wei Zhao, Yanwu Xu, Jing Hu, Hongmei Wang, Tianyuan You 261-368 Sleep Arousal Detection From Polysomnography Using the Scattering Transform and Recurrent Neural Networks Philip Warrick*, Masun Nabhan Homsi 262-262 Arousal Detection in Multimodal Sleep Recordings Using Hidden Markov Models Fernando Andreotti*, Oliver Carr, Kirubin Pillay, Navin Cooray, Huy Phan, Maarten De Vos

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Wednesday, September 26, 2018 12:15 PA2 Heart Rate Variability Room: Main Lobby 263-330 Age and Changes in Extracted Features of Lagged Poincare Plot Shahab Rezaei, Sadaf Moharreri, Nader Jafarnia Dabanloo, Saman Parvaneh*

264-181 Can Peak-Picked ECG Be Used for Heart Rate Variability? Richard Gregg*, Reza Firoozabadi, Saeed Babaeizadeh 265-205 Adding Two Dimensions to Heart Rate Variability Research Joachim A. Behar*, Ori Shemla, Yael Yaniv 266-234 Use of Approximation Entropy for Stratification of Risk in Patients With Chagas Disease Miguel Vizcardo*, Antonio Ravelo Garcia 267-312 Inhomogeneous Heart Rate Variability Spectral Complexity: A Preliminary Evaluation With Gravitational Stimuli Under Selective Autonomic Blockade Bolea Juan, Gaetano Valenza*, Raquel Bailón, Esther Pueyo, Riccardo Barbieri

268-14 Detection of Driver’s Drowsiness Using New Features Extracted From Heart Rate Variability Signal Gholamreza Attarodi*, Sahar Matla Nikooei, Nader Jafarnia Dabanloo, Parvin Pourmasoumi, Asghar Tareh

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Wednesday, September 26, 2018 12:15 PA3 Atrial Fibrillation Room: Main Lobby 269-11 Classification Atrial Fibrillation Using Stacked Autoencoders Neural Networks Javid Farhadi Sedehi, Gholamreza Attarodi*, Nader Jafarnia Dabanloo, Mehrdad Mohandespoor, Mehdi Eslamizadeh

270-360 Singular Spectrum Analysis of Atrial Activations Dominant Frequency to Predict Atrial Fibrillation Recurrence After Ablation Procedure Raquel Cervigón*, Javier Moreno, José Millet, Francisco Castells 271-365 Prediction of Atrial Fibrillation Recurrence by Pulmonary Vein Electrogram Correlation Raquel Cervigón*, Javier Moreno, José Millet, Francisco Castells 272-221 Action Potential Duration Restitution Kinetics During Atrial Fibrillation Derived From Optical Mapping Recordings in Goat Vladimir Sobota*, Stef Zeemering, Arne van Hunnik, Piotr Podziemski, Ulrich Schotten, Sander Verheule

273-147 Detection of Atrial Fibrillation From Short ECGs: Minimalistic Complexity Analysis for Feature-Based Classifiers Anara Abdukalikova, Denis Kleyko*, Evgeny Osipov, Urban Wiklund

274-90 A Novel Kernel-Based Method for Atrial Fibrillation Diagnosis Zouhair Haddi*, Bouchra Ananou, Stιphane Delliaux, Mustapha Ouladsine

275-201 Application of Joint Notch Filtering and Wavelet Transform for Enhanced Powerline Interference Removal in Atrial Fibrillation Electrograms Miguel Martínez, Juan Ródenas, José J Rieta, Raul Alcaraz*

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276-359 Atrial Rotor Modulation by Localized Dofetilide Application: An In Silico Study Sandra Perez-Buitrago, Juan P Ugarte*, Catalina Tobon 277-306 Functional Data Analysis for ECG Recordings of Paroxysmal Atrial Fibrillation Patients Before and After Pulmonary Vein Isolation Nuria Ortigosa*, Guillermo Ayala, Óscar Cano 278-66 Automatic Identification of Atrial Fibrillation by Spectral Analysis of Fibrillatory Waves Agnese Sbrollini*, Krizia Cicchetti, Alessia De Martinis, Ilaria Marcantoni, Micaela Morettini, Laura Burattini

279-268 A Robust Detection Method of Atrial Fibrillation Jing Hu*, Wei Zhao, Yanwu Xu, Jia Dongya, Cong Yan, Hongmei Wang, Tianyuan You

280-377 Interactive Exploration of Left Atrium Population-Level Morphology in Atrial Fibrillation Patients Tim Sodergren*, Anupama Goparaju, Alan Morris, Evgueni Kholmovski, Nassir Marrouche, Joshua Cates, Shireen Elhabian

281-127 Unsupervised k-Mean Classification of Atrial Electrograms From Human Persistent Atrial Fibrillation Tiago Paggi de Almeida*, Diogo C Soriano, Xin Li, Gavin S Chu, João L Salinet, Fernando S. Schlindwein, Peter J Stafford, G André Ng, Takashi Yoneyama

282-294 The Effect of Beat Interval on Ventricular Repolarisation in Atrial Fibrillation Marwa Al-Karadi*, Antony J Wilkinson, Philip Langley 283-320 Multiple P-Wave Morphologies in Paroxysmal Atrial Fibrillation Patients During Sinus Rhythm: A Simulation Study Dimitris Filos, Paschalis Korosoglou, Dimitrios Tachmatzidis, Nicos Maglaveras, Vassilios Vassilikos, Ioanna Chouvarda*

284-129 Developing an Iterative Tracking Algorithm to Guide a Catheter Towards Atrial Fibrillation Rotor Sources in Simulated Fibrotic Tissue Prasanth Ganesan, Hussein Zilouchian, Elizabeth Cherry, Arkady Pertsov, Behnaz Ghoraani*

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Wednesday, September 26, 2018 12:15 PA4 Cardiovascular Imaging Room: Main Lobby 285-12 A Nonlinear Adaptive Level Set for Intravascular Ultrasound Images Segmentation Mehdi Eslamizadeh, Nader Jafarnia Dabanloo, Gholamreza Attarodi*, Javid Farhadi Sedehi, Mehrdad Mohandespoor

286-76 A Temporal Area Variation Regularized Deep Learning Network for Left Ventricle Segmentation on Cardiac Magnetic Resonance

Gongning Luo, Shaodong Cao, Kuanquan Wang*, Henggui Zhang 287-361 Fetal Pulsed-Wave Doppler Atrioventricular Activity Detection by Envelope Extraction and Processing Eleonora Sulas*, Emanuele Ortu, Monica Urru, Alessandra Cadoni, Roberto Tumbarello, Luigi Raffo, Danilo Pani

288-73 Dyssynchrony Assessment in Arrhythmogenic Cardiomyopathy With Left Ventricular Involvement Yolanda Vives-Gilabert, Jorge Sanz, Antonio Cebrián, Raquel

Cervigón, Jose Millet*, Esther Zorio, Francisco Castells

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Wednesday, September 26, 2018 12:15 PA5 System Study Room: Main Lobby 289-341 The NInFEA Dataset for Noninvasive Fetal Electrocardiography Research Eleonora Sulas*, Giulia Pili, Emanuele Ortu, Elisa Gusai, Monica Urru, Alessandra Cadoni, Roberto Tumbarello, Luigi Raffo, Danilo Pani

290-23 Study of Blood Pressure During Controlled Respiration Alan Murray*, Masaki Hoshiyama 291-241 Cardiovascular Function Analysis of Untreated Hypertensive and Normotensive Participants in Cardiopulmonary Exercise Test Yahui Zhang*, Zhihao Jiang, Lin Qi, Lisheng Xu, Xingguo Sun, Xinmei Chu, Yanling Liu, Stephen E Greenwald

292-307 Approximate Entropy in Analysis of Cardiovascular Response to Lower Body Negative Pressure Test Agnieszka Strok, Gerard Cybulski*, Anna Gąsiorowska, Wiktor Niewiadomski

293-8 Pattern-Segmented Heart Rate Variability Analysis During Fetal Maturation Alexander Schmidt*, Dirk Hoyer, Uwe Schneider 294-20 A Lumped Parameter Model of Airway/Lung Mechanics Silvia Marconi, Claudio De Lazzari* 295-173 Incoherent Synchronization Between Resting State Respiratory Sinus Arrhythmia and Respiratory Movement in Depressed Patients With Suicidal Ideation Ahsan Khandoker*, Veena Luthra, Yousef Abouallaban, Namareq Widatalla, Herbert F Jelinek, Kyuichi Niizeki, Leontios Hadjileontiadis

296-300 Detrended Fluctuation Analysis of Heart and Respiratory Rhythm in Atrial Fibrillation Janko Zeković*, Šućro Madžgalj, Mirjana Platiša 297-328 Effects of Meditation on Heart Rate Stability Masaki Hoshiyama*, Alan Murray

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Wednesday, September 26, 2018 12:15 PA6 CV Mechanics Room: Main Lobby 298-386 Multiscale Modelling of Anthracycline Cardiotoxicity in Heart Contraction Alex Lewalle*, Steven Niederer 299-106 A Method for Removing Pacing Artifacts From Ultra- High-Frequency Electrocardiograms Petr Andrla*, Filip Plesinger, Josef Halamek, Pavel Leinveber, Ivo Viscor, Pavel Jurak

300-142 Comparison Between Theoretical and Experimental Reflection Coefficients in Flexible Tubes as a Function of the Mach Number Alessandro Giudici*, Wisam Hacham, Ashraf W Khir 301-22 Modelling Effect of Heart Failure on the Electrical Activity of Sheep Atria Nouf Alshwaira*, Henggui Zhang 302-199 Electro-Mechanical Delay in the Human Heart: A Study on a Simple Geometry Ekaterina Kovacheva*, Lukas Baron, Olaf Doessel, Axel Loewe 303-145 Gyrocardiography: A Preliminary Investigation of Cardiac Timings Parastoo Dehkordi, Kouhyar Tavakolian*, Vahid Zakeri, Farzad Khosrow-Khavar

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Wednesday, September 26, 2018 12:15 PA7 Medical Informatics & Technology Room: Main Lobby 304-269 Breathing Rate Estimation From the Photoplethysmography Using Respiratory Quality Indices Soumaya Khreis*, Di Ge, Guy Carrault 305-72 Pay More Attention with Less Parameters: A Novel 1-D Convolutional Neural Network for Heart Sounds Classification Yunqiu Xu*, Bin Xiao, Xiuli Bi, Weisheng Li, Junhui Zhang, Xu Ma 306-222 Feature-Based Cardiac Cycle Segmentation in Phonocardiogram Recordings Jussi Taipalmaa, Morteza Zabihi*, Serkan Kiranyaz, Moncef Gabbouj

307-44 TWA Simulator: a Graphical User Interface for T-wave Alternans Micaela Morettini*, Lorenzo Marchesini, Luca Alberto Pettinari, Andrea Tigrini, Ilaria Marcantoni, Agnese Sbrollini, Laura Burattini

308-98 Towards Personalized Aortic Valve Prostheses - A Sparse Representation of the Individual Leaflet Shape Jannis Hagenah*, Michael Scharfschwerdt, Floris Ernst 309-191 Effects of Microgravity on Action Potential Wave Propagation in Rat Transmural Ventricle Tissue Xiangyun Bai*, Kuanquan Wang, Qince Li, Cunjin Luo, Yacong Li, Henggui Zhang

310-176 Evaluation of Three-Dimensional Accelerometers for the Study of Left Ventricular Contractility Mireia Calvo, Jean-Luc Bonnet, Virginie Le Rolle*, Maxime

Lemonnier, Shota Yasuda, Wouter Oosterlinck, Alfredo

Hernández 311-215 Heartbeat Detection Using Three-Axial Seismocardiogram Acquired by Mobile Phone Federica Landreani*, Damien Golier, Amin Hossein, Jιrιmy Rabineau, Philippe Van de Borne, Enrico Caiani, Pierre- Franηois Migeotte

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312-316 A Statistical Comparative Study of Photoplethysmographic Signals in Wrist-Worn and Fingertip Pulse-Oximetry Devices Kais Gadhoumi, Kevin Keenan, Tania Pereira*, Rene Colorado, Karl Meisel, Xiao Hu

313-254 Robust Assessment of Photoplethysmogram Signal Quality in the Presence of Atrial Fibrillation Tania Pereira*, Kais Gadhoumi, Mitchell Ma, Rene Colorado, Kevin Keenan, Karl Meisel, Xiao Hu

314-80 A Computationally Efficient Method to Quantify the Biometric Properties of Ventricular Repolarization Irregularities in Healthy Human Subjects

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Wednesday, September 26, 2018 12:15 PA8 Tissue Modeling Room: Main Lobby 315-35 Effect of Tissue Elasticity in Cardiac Radiofrequency Catheter Ablation Models Argyrios Petras*, Massimiliano Leoni, Jose Guerra, Johan Jansson, Luca Gerardo-Giorda

316-280 Detailed Electromechanical Model of Ventricular Wedge Alexander Kursanov*, Vladimir Zverev, Leonid Katsnelson, Olga Solovyova

317-353 Baseline Fluorescence Removal Optimized for Optical Mapping Measurements Ilija Uzelac*, Flavio Fenton 318-189 Comparison of Depolarization and Repolarization in Mathematical Models of the Left Ventricle and the Thin Longitudinal Ventricular Slice Anastasia Bazhutina*, Anastasia Khokhlova, Konstantin Ushenin, Olga Solovyova

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Wednesday, September 26, 2018 13:45 SB1 Whole Heart Modeling Chairs: Gernot Plank and Niels Otani Room: 0.8 Rome 319-161 A Multiscale Investigation of Global Electrical Heterogeneity: Effects of Body Habitus, Respiration, and Tissue Conductivity 13:45-14:00 Erick Andres Perez Alday*, Haibo Ni, Christopher Hamilton, Annabel Li-Pershing, Bernard Jaar, Jose M Monroy-Trujillo, Michelle Estrella, Rulan Parekh, Henggui Zhang, Larisa Tereshchenko

320-79 Predicting Activation Patterns in Cardiac Resynchronization Therapy Patients 14:00-14:15 Angela Lee, Uyen Chau Nguyen, Justin Gould, Baldeep Sidhu, Benjamin Sieniewicz, Caroline Mendonca Costa*, Frits Prinzen, Gernot Plank, Christopher Rinaldi, Kevin Vernooy, Steven Niederer

321-271 T-Wave Changes Due to Cardiac Deformation Are Dependent on the Temporal Relationship Between Repolarization and Diastolic Phase 14:15-14:30 Robin Moss*, Eike Moritz Wόlfers, Gunnar Seemann

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Wednesday, September 26, 2018 13:45 SB2 Sleep and Autonomic Nervous System Chairs: Carolina Varon and Virginie Le Rolle Room: 0.9 Athens 322-357 Sensitivity Analysis of a Cardiorespiratory Model for the Study of Responses to Apnea 13:45-14:00 Gustavo Guerrero*, Virginie Le Rolle, Alfredo Hernandez 323-175 Investigating Sleep Fragmentation by Autonomic Arousals in Depressed Patients With Obstructive Sleep Apnea 14:00-14:15 Ahsan Khandoker*, Leontios Hadjileontiadis, Seada Kassie, Taoufik Alsaadi

324-192 The Cardiorespiratory Graph in Sleep Apnea and Associated Comorbidities 14:15-14:30 Carolina Varon*, Margot Deviaene, Dries Hendrikx, Sara Van de Putte, Dries Testelmans, Bertien Buyse, Sabine Van Huffel

325-21 Analysis of U-Shape Patterns in RR-Interval Time Series During Sleep 14:30-14:45 Sasan Yazdani*, Alexandre Cherqui, Nicolas Bourdillon, Gregoire Millet, Jean-Marc Vesin

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Wednesday, September 26, 2018 13:45 SB3 Ventricular Arrhythmias: Detection and Ablation Chairs: Pablo Laguna and Riccardo Barbieri Room: 0.4 Brussels 326-37 Fast Detection of Ventricular Tachycardia and Fibrillation in 1-Lead ECG from 3-Second Blocks 13:45-14:00 Filip Plesinger*, Petr Andrla, Ivo Viscor, Josef Halamek, Pavel Jurak

327-338 Man vs. Machine: Comparison of Manual vs. Novel 12- Lead ECG Algorithm to Predict the Ventricular Arrhythmia Origin to Guide Ablation Procedure 14:00-14:15 Roger Abächerli*, Ramin Ebrahimi, Peter van Dam, Ivo Strebel, Tobias Reichlin

328-208 Optimization of a Novel Activation-Repolarization Metric to Identify Targets for Catheter Ablation 14:15-14:30 Fernando Campos*, Michele Orini, Ben Hanson, Pier Lambiase, Bradley Porter, Christopher Aldo Rinaldi, Jaswinder Gill, Peter Taggart, Martin Bishop

329-388 Electromechanical Phase Singularity Dynamics During Cardiac Fibrillation 14:30-14:45 Jan Christoph*, Flavio Fenton, Stefan Luther

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Wednesday, September 26, 2018 13:45 SB4 Analysis of Ischemia Chairs: Johan deBie and Pavel Leinveber Room: 0.5 Paris 330-253 ST Segment Change Classification Based on Multiple Feature Extraction Using ECG 13:45-14:00 Hongmei Wang*, Wei Zhao, Yanwu Xu, Jing Hu, Cong Yan, Jia Dongya, Tianyuan You

331-18 Temporal Beat-to-Beat Variability of Repolarization Changes Predict Nonsustained Ventricular Tachycardia in Ischemic Heart Disease Patients 14:00-14:15 Jonathan Moeyersons*, Matthew Amoni, Bert Vandenberk, Carolina Varon, Karin Sipido, Sabine Van Huffel, Rik Willems

332-305 Electrocardiographic Comparison of Dobutamine and Bruce Cardiac Stress Testing With High Resolution Mapping in Experimental Models 14:15-14:30 Brian Zenger*, Wilson Good, Rob MacLeod 333-351 Novel Metric for Evaluating Ischemic Stress on the Torso Surface Using Laplacian Eigenmaps on Animal and Human Recordings 14:30-14:45 Wilson Good*, Burak Erek, Jaume Coll-Font, Brian Zenger, Dana Brooks, Rob MacLeod

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Wednesday, September 26, 2018 15:30 MD Closing Plenary Chairs: Willem Dassen and Teo Soo Kug Room: 0.4/0.5 Main Auditorium 334-39 Assessing a Warping Methodology for the Identification of Increased Cardiovascular Risk Based on the HR Profile Morphology (CTA Winner) 15:30-15:45 Julia Ramírez*, Stefan van Duijvenboden, Pablo Laguna, Esther Pueyo, Andrew Tinker, Pier Lambiase, Patricia Munroe, Michele Orini

335-346 Acute Effects of Respiratory-Gated Auricular Vagal Afferent Nerve Stimulation in the Modulation of Blood Pressure in Hypertensive Patients 15:45-16:00 Harrison Fisher, Jessica Stowell, Ronald Garcia, Roberta Sclocco, Jill Goldstein, Vitaly Napadow, Riccardo Barbieri*

336-288 On Deriving Tidal Volume From Electrocardiogram During Maximal Effort Test 16:00-16:15 Javier Milagro*, David Hernando, Jesus Lazaro, José Antonio

Casajús, Nuria Garatachea, Eduardo Gil, Raquel Bailón

337-112 Personalised Modelling Pipeline for Cardiac Electrophysiology Simulations of Infarct Patients 16:15-16:30 Caroline Mendonca Costa*, Aurel Neic, Gernot Plank, Eric Kerfoot, Bradley Porter, Benjamin Sieniewicz, Justin Gould, Baldeep Sidhu, Zhong Chen, Christopher A. Rinaldi, Martin J. Bishop, Steven A. Niederer