syllabus file

8/3/2019 Syllabus File

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Vocab Analogy Pattern Recognition Logarithms

Synonyms Classification Pattern Recognition Divisibility

Antonyms (Select the opposite of the given word.) Coding Pattern Recognition HCF and LCM

Sentence meaning Number Series Pattern Recognition Power

Direction sense Decimal Fractions

Grammar CDL Numbers

Sentence completion Blood relations Permutations and Combinations

Sentence error Puzzles Probability

Sentence improvement Logical word sequence Word ProblemComprehension (order) Selection decision table Word Problem Profit

Data sufficiency Word Problem Interest

Reading Comprehension (RC) Objective reasoning Word Problem Speed

Word Problem Inverse


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CATEGORY SUBCATEGORY

Theoretica

Operators

r t met c, ssgnment,

Boolean Logical Operators,

Bitwise and Bitshift Operators,

Increment and Decrement,

Relational, Conditional Operator,

Operate-Assign Operators 0

Data Types and Variables

r m t ve ata ypes - yte, s ort, nt, ong, c ar, oat, ou e, an

boolean,

Non-primitive Data Types,

Usage of Data Types,

Literals - string, numeric, character, floating-point, boolean,

Declaring Variables,

Variable Names,Scope and Lifetime of Variables 1

rrays

ec arat on o rrays,

Construction of Arrays,

Initialization of Arrays,

Elements of Arrays,

One and Multi-dimensional Arrays,

Alternative Arrays 0

Classes

Class Declaration,

Declaring Member Variables,

Defining Methods,

Scope of Methods 0

Method Parameters,

Static Methods,

Final Classes 0

Constructors,Object Classes,

Abstract Classes,

Nested Classes: 0

Static Member Types,

Non-static Member Classes,

Local Classes,

Fundamental Classes: Object, Wrapper, String Class 1

Objects

Creating Objects,

Using Objects,

Encapsulation,

Constructors,

Access Modifiers,

Using the this Keyword 0

Object Finalization,Field Initializer,

Return Value,

Method to Box Class,

Garbage Collection 1

Interfaces

ec ar ng an nter ace,

Interface Implementation,

Extending Interfaces,

Using Interface as Type,

Rewriting Interface,

Runnable Threads,

Variables in Interface 1

Inheritance

Member Access and Inheritance,

Overriding Method,

Hiding Members,

0

Casting,

Polymorphism,

Using the super Keyword,

Object Class 1

Packages

e n ng ac ages,

Creating Packages,

The Import Statement,

Static Imports,

Casting,

Scope of Packages 1

Exception Handling

ec ar ng xcept ons,

Exception Hierarchy,

Exception Matching,

Exception Methods,

Exception Types - Try, Catch, Finally,

Throw Statement,

Erros and Runtime Exceptions,

Assertions 1

File and Streams

e ass,

Recording and Writing Files,

Input and Output,

Byte Streams - Input Streams and Output Streams,

Character Streams - Readers and Writers,

Basic and Filtered Streams,

Converting Byte Streams to Character Streams 2


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Threads

rea ng rea s,

Threaded and Non-Threaded Applications,

Thread Priorities,

Thread Synchronization,

Coordinating and Interrupting Threads,

Runnable Interface 1

Generics

ype rasure,

Type Boundaries,

Parameterized Types,

Wildcards,

Generic Methods and Constructors,

Strengths and Weaknesses of Generics,

Legacy code and Generics 1

Inner Classes

nner asses,

Member Classes,Local Classes,

Anonymous Classes,

Static Nested Classes,

Instance Initializers 1

Strings

String Class,

StringBuilder and the StringBuffer Classes,

Strings and Memory

Total 1


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App. Base total

2

0

1 1

1

1

1

0

2

0

2 2

3

0

2 2

2 2

1 2

3

3

2

3


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2 2

0 1

1 2

2 1

23 26


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ATEGORY SUBCATEGORY

Theoretical App. Based

lasses Defining Classes 0 0

Instantiation and using Classes 0 1

Constructors and Destructors 1 1

Using Constructors 1 1

Member Functions 0 1

Static Members 1 1

Constant Member Functions 0 1

Inline Implementation 1 1

Access Control 0 1

Structures and Classes 1 0

Introduction to Function Overloading 0 1

Overloaded Operators 0 1

TOPIC TOTAL = 7 total = 2 total = 5

bjects Destructors 1 0

Default Constructors 0 0

Construction and Destruction 0 1

Local Variables 0 0

Class Objects as Members 0 1

Constant Member Functions 1 1

Object as Function Arguments 0 1


Inheritance Concepts of Inheritance 1 1

Protected Keywords 1 1

Derived Classes and class constructors 0 1

Constructor and Destructor Calls 0 1

Types of Inheritance - single, hierarchical, multiple, hybrid 1 1

Base Class 0 0

Public and Private Inheritance 1 1


Exceptions Throw and Catch 0 1

Inheritance and Exceptions 1 0

Standard Exceptions 1 0

Exception Types 1 1

Exception Hierarchies 1 1

TOPIC TOTAL = 1 total = 0/1 total = 1/0

perator Overloadi Overloading Binary, Unary Operators 0 1

Overloading And Conversion 0 1

Stream Operators 0 1

Overloading Functions 0 1

Operators and User-Defined Types 0 1


File and Streams File Streams 1 1

String Streams 1 1

Standard Streams 0 1

Input and Output Streams 0 0

Streams Classes 0 1

File Pointers 0 1

Header Files 1 1

File Input and Output 0 2

Error Handling in File I/O 1 1

Manipulators 0 0

Command Line Argument 1 1

TOPIC TOTAL = 5 total = 1/2 total = 4/3

Polymorphism and Overloading ( method and operator) 1 1

Virtual methods 1 1

Compile time Polymorphism 1 0

Run time Polymorphism 1 0

Built-in streams 1 0

Friend and Static Function 1 1

Assignment And Copy Initialization 1 1

This Pointer 1 1

Dynamic Type Information 0 1


Pointers and Arrays Pointers and Instances 0 0

Dynamic Memory Allocation 0 1

Memory Management - New And Delete, Pointers To Objects,

Debugging pointers 0 1

Pointers into Arrays 0 0

Pointers and Constants 0 0

Pointer to Void 0 0

String Arrays Fundamentals 0 0

Arrays as Class Member Data 0 1


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Object Arrays - Creating, manipulating 0 1

TOPIC TOTAL = 1 total = 0 total =

Types and Declarati Fundamental Types - -

Booleans - -

Character Types - -

Integer Types - -

Floating-Point Types - -

Structure of Declaration - -

Declaring Multiple Names - -

Scope and Initialization - -

Objects and Lvalues - -

TOPIC TOTAL = 0

Templates (Advanc Function Templates 0 1

String Template 0 1

Specialization 0 1

Deviation and Templates - Parameterization and Inheritance 0 1

Standard Template: 0 1

Algorithms 0 1

Containers - Sequence, Associative 0 1

Function Objects 0 1

Iterators0 1

Strings 0 1

TOPIC TOTAL = 1 total = 0 total =

TOTAL = 25


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Category Sub category

Complexity

E - Easy, M - Medium, H - Hard

SQL Basics

Creating a MySQL Database E

Using the mysql Command-Line Tool E

Statements E

Names: table names, column names EMySQL Data Types, Constants (Numeric, String, Date

and Time, Symbolic Constants) E

Expressions E

Built In functions E

Missing data (NULL values) E

Table Creation E

Populating and Modifying Tables E

Simple Queries:

The select Clause (Retrieving Individual, multiple, all

Columns) E

The from Clause E

Query Results, Simple Queries E

Where Clause E

The group by and having Clauses Ee or er y ause or ng a a, or ng y

Multiple Columns, by Column Position, Specifying Sort

Direction) E

Rules for single table query processing E

Combining Query Result (UNION) M

Filtering & Search Conditions

Condition Evaluation E

Building a Condition ECondition Types E

Combining Where clauses E

The Comparison Tests (, =, =, ) E

Compound Searches (AND, OR, NOT) E

Advanded Data Filtering

Using IN and NOT operators E

Using Exists and NOT EXISTS operators M

BETWEEN operator E

Using the LIKE Operator M

Using Wildcards M

More SQL commands (TRIM, SUBSTR,

CONCATENATE, LENGTH, REPLACE, DATEADD etc.)

Grouping &Aggregation In SQL

Grouping Concepts MAggregate Functions (SUM, COUNT, AVG, MIN, MAX,

etc) M

Generating Groups M

Group Filter Conditions M

Multiple Grouping Columns M

Restriction on Grouped Queries M

Duplicate Row Elimination (DISTINCT) M

Querying Multiple Tables

Understanding JOINS M

Joining Three or More Tables M

Different Types of Joins:

Simple Joins M

Natural Join H

Self-Joins H

Equi-Joins Versus Non-Equi-Joins H

Outer Join (Left & Right Outer Joins) H

Inner Joins H

Cross Joins & Union Joins H

Table Aliases H

Table Multiplication & rules for table Multiplications M

Join Conditions Versus Filter Conditions H

Using Joins with Aggregate Functions H

Using Joins and Join Conditions M

*All questions need to be on commands, programming statements, etc. Less than 20% questions should


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Subqueries

What Is a Subquery? M

Subquery Types M

Write single-row and multiple-row subqueries M

Subquery Search conditions M

Subqueries and joins H

Nested subqueries H

Correlated Subqueries H

Noncorrelated Subqueries H

Filtering by Subquery HUsing Subqueries As Calculated Fields H

When to Use Subqueries M

Using the Set Operators

Set Theory Primer H

Set Theory in Practice H

Describe set operators H

Set Operation Rules H

Use a set operator to combine multiple a single query HControl the order of rows returned H

Manipulating Data

Describe each DML statement E

Understanding Data Insertion (INSERT) E

Copying from One Table to Another E

Updating Data (UPDATE) E

Deleting Data (DELETE) E

Merge rows in a table (MERGE) E

Data Integrity

What is Data Integrity E

Requried Data ESimple Validity checking (Column check constraint,

Domains) E

Entity Integrity (Uniqueness constraints, NULL values) E

Referential Integrity (Foreign Keys) E

Creating Databases

Data definition Language (DDL) E

Creating databases E

Table definitions:

Creating table (CREATE TABLE) E

Removing a table (DROP TABLE) E

Changing a table definition (ALTER TABLE) E

Deleting tabale data (TRUNCATE TABLE) E

Renaming a table (RENAME TABLE) E

Constraints definitions (Assertions and Domains) M

Aliases and synonymns (CREATE /DROP alias) M

Indexes:

Create Index H

Delete index (DROP INDEX) H

Sequencing:

Creating a sequence (CREATE SEQUENCE) H

Droping a Sequence (DROP SEQUENCE) H

Using a sequence H

Removing Database (DROP DATABASE) E

Views

Understanding Views (advantage & Disadvantages of

a view) M

Creating Views: M

Horizontal View M

Vertical View M

Row / Column subset view M

Grouped Views M

Joined Views M

Updating a View M


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Drop ng a V ew M

Transaction Processing

Multiuser Databases H

Understanding Transaction Processing H

Controlling Transactions H

Transaction control languages (TCL) H

COMMIT and ROLLBACK H

SAVEPOINT and SET TRANSACTION H

Transaction Models HTransaction and Multiuser transaction H

Locking (shared, exclusive locks, deadlock, advanced

locking techniques) HVersioning (operations, advantages and

disadvantages) H

SQL Security

User Ids, Security Objects, Privileges H

Views and SQL security H

Data Control Language (DCL): H

What is DCL? H

Granting Privileges (GRANT) H

Revoking Privileges (REVOKE) H

TOTAL


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CATEGORY Number of questions

Basic unix commands and architecture 2

General purpose utilities 2

File system, Handling Files and file attributes 3

The vi Editor 2

Different shell types and configuration files 1

Process: Concept and basic commands (current, foreground, current process n killing) 2

Customizing the environment 2

Simple Filters and those using Regular Expression (Grep and SED) 2

Basic shell Programming 2

System Administration 2

The X window System 2

Networking Tools 2

awk- An advanced filter 1

TOTAL 25

* For each category, make 1 hard question and rest easy

* In case of only one question in the category, make either hard or simple, as per discretion


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CATEGORY SUB CATEGORY NUMBER OF QUESTIONSVendor Management 2Adding Vendors Naming/numbering conventions, Multiple vendor records, documents

Requests on Vendor Masters Change Vendor Master, Delete Vendor Master, Block/unblock,

Advanced Issues which come up in vendor setup Issues with government as a

Invoice Processing 10

Invoice checking Basic fields of an invoice and their meaning, invoice categories, Key

PO based processing and matching 2-way/3-way/4-way matching, Risks in 2 way matchdocuments of

Non-PO based processing Process, Issues and challenges

Advanced Invalid invoice, Exception handling, Coding issues, Reverse transfer

Payments 11

Status of payments Different stage the payment could be in, how to identify, to-do

Types of payment methods Employee payment vs vendor payment, duplicate payments, refund to

Concepts of discounts Net 30

days credit terms, 5/1

5 - what does this mean,Unpaid Aps Terminologies - block/hold/park, reasons for unpaid Aps, Common

Month End Accrual, reconciliation with general ledger & reconciliation of vendor

Advanced Duplicate payments, Refund to customers, Inter company payments,

Misc 2SAP/Oracle/JDE Transaction Codes, Document verification for adding or maintaining

Help Desk E-mail & Call receipt & respond behavior, researching an enquiry in

TOTAL 25


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CATEGORY SUB CATEGORY NUMBER OF QUESTIONSCustomer Master Data 4

Adding Customer Naming/numbering conventions, info required to

Requests Change is CMD, Customer Blocking, Update records,

Advanced Issues with naming conventions, multiple address

Order Management 3

Receiving orders Ways of receiving orders, Order Requisition, filling

Order Entry Role of Order entry and expediting, Key fields

Advanced Key reasons for error, impact, Partial fulfillment or

Credit 4

Credit Team & agencies Role of credit team, credit request forms, DNB and

Credit ratings Different rating scales, how do they look

Advanced Role of credit team, credit request forms etc, What

Cash Apps 5

Concepts & basics How cash is applied, role of Cash applicator, modes

Applications & challenges Applying unapplied cash, applying wire transfer

B2B Collections 6

AP Basics

Collection Basics Different payment terms, How to read them on

Recovery & resolution follow ups, query handling, mock scenario

Deductions 4

Basics Types of deductions, role of deduction specialist,

Treating Deducations Deductions from backups, validating deductions,

Advanced returned/damaged goods, price not mentioned, tax

Total 26


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CATEGORY SUB CATEGORY NUMBER OF QUESTIONSJournal Entries 2

Chart of Accounts Asset Accounts, Liability accounts, Equity Accounts, Expense

Journal Entries Samples journal entries, journal entries for accrual of

Account Reconciliation 4

Theoretical Critical controls, Best Practices, Types of A/c Recon, Bank a/c

Practical Sample Account Reconciliation specially cash and bank,

General Accounting Types of accounting books, Matching, Accrual, rules of 6

Closing and reporting Close Management, Statutory/GAAP Adjustments (Indian), 3

Fixed Asset 4

Basics Adding new FAs, critical info needed, Part sale/disposition,

Audit (for all financial statements (not just fixed assets)) Controls needed, audit trial, key parameters, physical audit, 1

Inter Company 5

Transfer Inter co transfers, documents needed, process to ensureTie out

Misc ERP systems knowledge, Lease Accounting/royalty accounting, 0

Total 25


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General Principles of Accounting Types of accounts

Rules of accounting

Concepts of accounting such as matching, accrual, etc.

GAAP(Generally Accepted Accounting Principles)/ GAP(general accounting procedures)

Types of errors: concept and effect on trail balance

Preparation of Final Accounts Simple journal entries

Purpose of Trial Balance

Trading Account

P&L account and balance sheet

Items of balance sheet

Depreciation Methods of depreciations

Simple numerical problems

Ratio analysis Types of ratio

quick ratio

debt/equity ratio

solvency ratio etc. (and their uses)

Cash book Concept of contra entry

Types of subsidiary books (concepts and purpose)

Types of Costs & Revenue Product cost

Period cost

Opportunity cost

Decision-making cost

Controllable and uncontrollable costs

Types of Revenue

Basics of Bank Reconciliation Statement

Basic Knowledge of accounting standards and transfer pr


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-

Marketing Management Customer Value, Loyalty

Consumer, Business Markets

Market Segments and Targets

Brand Equity

Brand Positioning

Product Strategy

Designing and Managing Services

Pricing Strategies

Integrated Marketing Channels

Retailing, Wholesaling, and Logistics

Marketing Research Application and Limitations

Sampling - Sample Selection, size of SampleChapter

Questionnaire Development

Data Collection (Primary/Secondary)

Data Preparation and Processing

Data Analysis and Interpretation

Research Process and Design

Exploratory and Qualitative Research Techniques

Market and Sales Analysis Research

New Product Development

onsumer Behavior Consumer behavior and product-market choice

Customer value and market segmentation

Market selection

Target market decision

Response to Market Environment and Competition

Selecting market opportunity

Consumer Motivations

Personality and Attitudes and Consumer Behavior

Learning and Consumer Involvement

Marketing Planning and Strategy Marketing Strategy

Understanding Competition

Strategy Selection and Control

Marketing Productivity

Strategic Tools

Growth Strategies

Product Strategies

Pricing Strategies

Distribution and Promotion Strategies

Global Market Strategies

ales and Distribution Management Personal Selling Process

Sales Planning and Budgeting

Sales Territory

Product Lifecycle Issues

Sales forecasting -

Managing the sales forecasting process

Sales forecasting performance measurement

Time series forecasting techniques

Regression analysisQualitative sales forecasting

Sales forecasting systems

Marketing Channels

Retailing

Wholesaling

Warehousing

Transportation

Channel Information Systems

Distribution Channels in ServicesDistribution Planning and Control

Brand Management Brand Identity and Brand Positioning

Brand Communication

Brand Equity and Valuation

Marketing Programs and Communications for Brand Equity

Measuring Sources and Outcomes of Brand Equity

Co-Branding, Brand Extension and MultibrandsBranding Strategy

Managing Brands over Time and Market Segments

Brand Licensing and Franchising


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o e o n ormat on n ran anagement

Advertising Management Integrated Marketing Communications

Segmentation and Positioning

Brand Equity, Image and Personality

Group Influence and Word-of-Mouth Advertising

Production and Implementation

Advertising Regulation

Global Marketing and Advertising

Principles of Economics The Market Forces of Supply and Demand

Elasticity and Its Application

Supply, Demand, and Government Policies

Consumers, Producers and the Efficiency of Markets

The Costs of Production

Monopoly, Oligopoly, Monopolistic Competition

Macroeconomics - Measuring A Nations Income, Cost of Livin

Production and Growth

Saving, Investment, and the Financial SystemMoney Growth and Inflation

Aggregate Demand and Aggregate Supply

TOTAL


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NUMBER OF QUESTIONS

8

3

3

5

3


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2

3


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NUMBER OF QUESTIONS

Individual and Group Behavior Personality, Self-awareness 9

Values and Attitudes

Motivation - the WHYS of Human Behavior

Work and Conditions of Work

Skills for Managing Teams: Communication, Conflict, Power and Influence.

Stress Management

Group Development and Cohesiveness

Group Performance and Decision Making

Intergroup Relations

Managerial Effectiveness: Traits and Skills

Interpersonal Communication and Group

Effective Leadership

Conflict and Negotiation

rganisational Structure and Design Determinants of Organisational Design 5

Parameters of Organisational Design

Organisation and Environment

Organisational Strategy

Organisation and Technology

Types of Organisational Structures

Power and Conflicts in Organisations

Organisational Decision-Making and strategy-Formulation

Organisational Culture

Organisational Failure and Pathology

Organisational Change and Development

Organisational Learning and Transformation

Industrial Relations and Employment LaEmployment Laws: 1

Trade Unions Act, 1926

Industrial Employment (Standing Orders) Act, 1946

Industrial Disputes Act, 1947

The Payment of Bonus Act, 1965

Employees Provident Funds (and Misc. Provisions) Act, 1952

Workmens Compensation Act, 1923 (WC Act)

Employees State Insurance Act, 1948 (ESI Act)

Payment of Gratuity Act, 1972 (PG Act)

Child Labour (Prohibition & Regulation) Act, 1986

Industrial Relations:

Approach -

The systems model

The Pluralist Approach

The Structural Contradictions Perspective

Participants -

Trade Unions

State

Employers/Management

Industrial Relations in Emerging Scenario

Future Trends

Human Resource Planning Productivity Management 1

Quantitative and qualitative determination of Human Resource requirements

The Human Factor in the Application of Work Study

Working Conditions and the Working Environment

Methods Study; the Approach to Methods Study

Work Measurement - Purpose and the Basic Procedure

Techniques of Work Measurement

Strategic Planning and Human Resource Planning

Human Resource Planning in Changing Context

Human Resource Demand Forecasting

Human Resource Supply Estimates

Human Resource Information System Computers and Computer Based Information Systems 2

Management Concepts and CBIS

Management Information Systems

Functional Applications

HRIS Life Cycle/HR responsibility in each phase of HRIS development

Pre implementation stage of HRIS -

HRIS Planning, Expectation

Productivity Through HRIS

Cost-benefit Value Analysis

Getting Management Support for HRIS

Limitations of Computerisation of HRIS


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Implementation: Tools in HRIS Development

Packaged HRIS / Business Process

Re-engineering, Enterprise Resource Planning Systems

2

Strategic HRM Business Strategy and Organisational Capability

Global Environment of HR: Change & Diversity

Universalistic, Contingency and Configurational Approaches

Strategic HR Planning Acquisition and Development

Corporate Strategy and Career Systems

Managing Employee Relations: Unions and Strategic Collective Bargaining

Change, Restructuring and SHRM

Corporate Ethics, Values and SHRM

Evaluating the Effectiveness of SHRM

Training and Development Human Resource Development 0

A Systematic Approach to Training

Needs Assessment

Objective Setting

Programme Design: Incorporating Learning Principles

Instructional Techniques: An Overview

Training Evaluation: Evaluation Designs, Reaction, Learning, Job Application, Business Impact and ROI Process Mod

Training Trends Worldwide

Strategy and Training

Training Department and Trainers Roles

Moving from Training to Performance

Performance Management Objectives of P A 2

Issues and Problems in P A

Job Description and P A

Job Analysis in P A Systems

Methods of P A

Appraisal Forms and Formats

Measurements in P A

Performance Management

Process and Documentation of P A

Appraisal Communication

Performance Feedback and Counselling

Implications of Management Styles on P A

P A and its Organisational Implications

Selection Job Analysis in Human Resource Planning, Recruitment and Selection 1

Application Forms and Reference Checks

Selection Interview

Other Selection Devices

Selection Decision Making

Selection in New Type of Organizations

Basics of HR 2

TOTAL 25


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Basics of HR 2 16

Human Resource Information System 2 16

Human Resource Planning 1 8

Individual and Group Behaviour 9 72

Industrial Relations and Employment 1 8

Organizational Structure and Design 5 40

Performance Management 2 16Selection 1 9

Strategic HRM 2 16

Training and Development 1001


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CATEGORY NUMBER OF QUESTIONS

Word comparison 2

Directly related words 1

Letter occurrence 1

Number set 1

Passage inference 4

Rules 4

Feedback form 0

Address range 0

Increasing, decreasing order 4

Parameters 4

Image - memory 0

Image comparison - visual 1

Visual atd 12

TOTAL 34


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AIN MODULES MODULE CATEGORY SUB CATEGORY

MOLECULAR BIOLOGY Molecular Genetics Genome Structure and Organization

Organization of prokaryotic and eukaryotic

genomes

(total = 50%) Satellite DNA

Rearrangement and amplification of DNA in

the genome

DNA Replication and Repair DNA replication models and mechanisms

DNA damage, DNA repair and recombination.

Enzymes and proteins involved in replication

Semi-conservative theory of Meselson and

Stahl

Chromosome and Nucleic Acids Structure and functions of DNA and RNAWatson and Crick model of DNA

Morphology and structural organization of

chromosomes

Ultrastructure of nucleic acids

Transcription Prokaryotic transcription:

Structure and function of RNA polymerases

Mechanism of initiation of transcription

Promoters, operators and regulators

Termination - Rho-dependent and

independent; Anti-terminationTranscriptional regulation - Positive and

negative

Operon concept - lac, trp, ara, and his,operons

Eukaryotic transcription

RNA polymerases

Eukaryotic promoters and enhancers; General

Transcription factors

Activators and repressors

Post Transcriptional Modifications

Splicing and RNA editing

Translation Translation machinery and Ribosomes

Universal genetic code and codons

Wobble hypothesis

Mechanism of initiation, elongation and

terminationCo - and posttranslational modifications

Inhibitors of protein translation

Gene Expression in Prokaryotes and

Eukaryotes

Regulation of Gene expression in prokaryotes

and eukaryotes

Insertional elements and transposons

Mutations Types: spontaneous and induced

Mutagens

Mutagenesis and mechanisms

Expression of mutations - gene mutation

Point mutations

rDNA technology Cloning and vectors used in cloning

Restriction endonucleases (REs): classification

and mechanism

(total = 30%) PCR technology and its application

cDNA synthesis

Introduction of recombinant DNA into hosts

Plasmids - classification, Conjugation and

compatibility

Bacteriophages - The phage infection cycle

M13 - a filamentous phage 22

Phagemids; Lambda vectors; EMBL; Cosmids

Artificial chromosome vectors (YACs; BACs)

Enzymes used in rDNA technology Nucleases

Ligases

Polymerases

Linkers

Blunt ends and sticky end ligation

Sequencing techniques The methodology for DNA sequencing

Pyrosequencing

Edman Degradation, N Terminal Sequencing

The shotgun approach to genome sequencing

The clone contig approach

Transgenics Concept of transgenics in plants and animals

Markers and reporter genesDNA libraries Screening of genomic libraries


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Genetic complementation technique

Immunochemical techniques, ELISA

cDNA libraries

Recombination

Transformation - the uptake of DNA by

bacterial cells

Transfection - particle bombardment

Conjugation and transduction

Genomics Mendelism Mendelian principles

(total = 20%)

Interaction of Genes - supplementary and

multiple factors; complementary genes

Chromosomal basis of inheritence Chromosome characteristics and structure

Euchromatin and heterochromatin

Genetic Recombination in Eukaryotes -

heterochromatization, sex chromatin

Quantitative inheritance

Linkage and crossing over

Chromosome mapping

Gene and the genome Gene families, clusters

Pseudogenes and overlapping genes

Concets of allosomes and autosomes, XX-XY,

XX-XO,ZW-ZZ, ZO-ZZ types

Genome annotation - ORF, homology

searching

Determining the function of an unknown gene

Genetic variations and gene mapping

Chromosomal Variations - structural and

numerical aberrations

Construction of genetic and physical maps

Total for Molecular Biology module

LAB CHEMISTRY Analytical techniques in biotech Microscopy

Construction and working principles of

different types of microscopes

(total = 50%)

Spectroscopy Atomic and molecular electronic spectroscopy

Vibrational spectroscopy and electron and

nuclear spin orientation in magnetic fields

STMNMR Spectroscopy and 2D NMR (COSY,

NOSEY, SECSY techniques)

Electrophoresis Agarose gel electrophoresis, PFGE

Blotting techniques

Native and SDS Polyacrylamide gel

electrophoresis, 2 D electrophoresis

Chromatography Gel permeation chromatography

Adsorption (ion exchange, affinity)

chromatography

Partition chromatography

HPLC

Protein purification

Radioactivity Neutron Activation Analysis

Isotope dilution analysis

Radio-immunoassay

Radiotracers

Spectrometry MALDI-TOF

Mass spectrometry

Crystallography Crystallization of biomolecules

X-ray crystallography

Protein Crystallography

Fermentation technology Bioreactor and fermenters

Fermenter design-mechanically agitated;

Pneumatic and hydrodynamic fermenters

(total = 50%)

Types of fermentation Batch, fed batch and continuous

Solid substrate, surface and submerged

fermentation

Fermentation process Fermentation media

Animal and plant cell cultivation

Air sterilization

Upstream processing Media formulationSterilization


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Aeration and agitation

Instrumentation, measurement and control of

bioprocess parameters

Down stream processing Bioseparation techniques

Purification by chromatographic techniques

Reverse osmosis and ultra filtration

Drying and Crystallization

Effluent treatment

Total for Lab Chemistry module

hemistry Physical & General Chemistry Atomic structure

Setting up the Schrdinger equation for the

hydrogen atom. Qualitative solution. Shapes

ofs ,p , d andf orbitals and their overlap

behaviour.

Chemical Bonding

Covalent and ionic, polarity of bonds, dipole

moments and information they convey about

the structure of the molecule. Directional

nature of the chemical bond, simple concepts

of hybridization involving s ,p , and d orbitals.

Lewis structures and VSEPR theory.

Predictions of geometries based on these

concepts.

Gaseous state

The gas laws, kinetic theory treated

qualitatively. Ideal gas law and its application.Non ideal behaviour of gases and van der

Waals' equation. Dalton's law, the Avogadro

constant, the mole, Graham's law of diffusion,

simple numerical problems on the above.

Chemical Thermodynamics

System and surroundings, state variables.

Work and heat. Work done in reversible and

irreversible expansions of ideal gases. First

Law and its implications. Energy and Enthalpy.

Specific heats at constant volume and

pressure and their relationships.

Thermochemistry. Second Law ofThermodynamics and its applications. Concept

of entropy.

Chemical & ionic equilibrium

Criteria for spontaneity and equilibrium. Free

energy changes in chemical reactions. Gibbs-

Helmholtz equation (no derivation) and its

application. Factors affecting equilibrium,

equilibrium constants, Le Chatteliers principle

and application thereof. Small numericals

based on these concepts. Application of

equilibrium concepts to ionic equilibria, pH,

pKa and pKb, buffer solutions, solubilities andsolubility products, influence of pH on

determining protonation states, acid-base

equilibria.

Solutions and Colligative properties

Types of solutions, expression of

concentration of solutions of solids in liquids,

solubility of gases in liquids, solid solutions,

colligative properties - relative lowering of

vapour pressure, elevation of B.P., depression

of freezing point, osmotic pressure,

determination of molecular masses using

colligative properties, abnormal molecular

mass.

Electrochemistry

Redox reactions, conductance in electrolytic

solutions, specific and molar conductivity

variations of conductivity with concentration,

Kohlrausch's Law, electrolysis and laws of

electrolysis (elementary idea), dry cell

electrolytie cells and Galvanic cells; lead

accumulator, EMF of a cell, standard electrode

potential, Nernst equation and its application

to chemical cells, fuel cells; corrosion.


28/36

Chemical Kinetics

Rate aws an t e r express on, rate constants

and their dependence on various factors like

temperature, concentration and catalysis.

Potential energy surfaces (rough idea), Types

of catalysis, including enzyme catalysis and

the Michaelis-Menten equation.

Inorganic Chemistry Periodic Table and periodic properties.

Variation of periodic properties across rows

and periods, anomalous behavior of the first

element in each group.

s- and p-block elements.

Biological significance of some of these

elements.

d-block elements

General introduction, electronic configuration,

occurrence and characteristics of transition

metals, general trends in properties of the

first row transition metals: metallic character,

ionization enthalpy, oxidation states, ionic

radii, colour, catalytic property, magnetic

properties, interstitial compounds, alloy

formation.

Coordination compounds

Introduction, ligands, coordination number,

colour, magnetic properties and shapes,

IUPAC nomenclature of mononuclearcoordination compounds bonding; isomerism,

importance of coordination compounds (in

qualitative analysis, extraction of metals and

biological systems).

Organic Chemistry

Purification and characterization of

organic compounds.

Crystallization, sublimation, distillation,

fractional distillation, steam distillation,

distillation under reduced pressure,

extraction, chromatography (paper, column,

reference values). Detection of nitrogen,

sulphur, phosphorus, halogens. Estimation ofcarbon, hydrogen and nitrogen. Calculation of

empirical and molecular formulae.

IUPAC nomenclature of organic compounds,

resonance, inductive, electromeric effects,

conjugation, hyperconjugation.

Functional Groups: Classification and

characteristic reactions. Isomerism: Positional,

functional group, tautomerism, geometrical

and optical isomerism.

Types of organic reactions

Substitution, addition, elimination.

Mechanisms, curved arrows and other

notations. Reactive intermediates in organic

chemistry, their relative stabilities and how

these affect product ratios and course of

reactions. Free radical mechanisms.

Biochemistry Structure and catalysis Amino acids Classification, properties

Proteins

3D structure of proteins, classification based

on structure and functions, structural

organization of proteins (primary,secondary,tertiary and quaternary structures)

Enzymes

Classification, catalysis, kinetics, regulation

(fine, coarse and metabolic control)

Coenzymes and cofactors

Carbohydrates

Structures, properties and classification,

carbohydrates as a source of energy

Lipids

Structure, properties, classification and

functions

Vitamins

Water soluble and fat-soluble vitamins.

Dietary source

Nucleic acids, nucleotides Purine and pyrimidine bases

Metabolism and bioenergetics Metabolic pathways Glycolysis

Krebs cycle/citric acid cycle

Total for Chemistry

Total for Physical Chemistry

Total for Inorganic Chemistry

Total for Organic Chemistry

Basic Concepts


29/36

Pentose phosphate pathways

Amino acid oxication and production of urea

Oxidative phosphorylation and

photophosphorylation

Carbohydrate biosynthesis

Lipid biosynthesis

Oxidative phosphorylation and

photophosphorylation

Fatty acid oxidation and biosynthesis,

photosynthesis

Bioenergetics Principles of bioenergetics

Thermodynamics of biological systems

Total


30/36

REQUIRED WEIGHTAGE

1

1

1

3

1

2

0

3

3


31/36

1

1

1

1

total = 20 questions (mol bio =

10, rdna = 6, genomics = 4)

1

1

3

3

2

1

1

1

2

1

3

1


32/36

3

total = 22 questions

1

2

2

1

2

2


33/36

1 Electroche 2

11

1

5

1

3

6

22

1

1

1

1

1

1

1

3

2

4


34/36

2

12


35/36

Categories Sub Categories Detailed Topics Theoretical

Applicati

on/Scena

rio based

Networking Basic Basics: Protocols HTTP, IP, TCP, N/w access, SMTP, FTP, UDP etc. 1 1

Nework Address Translation 1

Ethernet

Standards, Layers, Logical Link Control, MAC,

Implementation 1 1

Network Addressing: IPv4, IPv6

Protocols and Addressing, Configuration, Types,

Configuring router and routing protocols,

Tunneling etc. 2

OSI ModelModel, Layers, Role, Functionality and Protocolsfor different layers 1

TCP-IP Model

Model, Layers, Role, Functionality and Protocols

for different layers 1

Types of N/W, Planning and Cabling N/Ws

Types of N/W. Making Connections, Device

Interconnections, Developing Address Scheme,

Subnets 2

Network

Implementing VLAN

Configuration and Troubleshooting, Protocols,

Routing Vlans 1

Routers and Routing Fundamentals, Protocols, Router Configuration 1 1

WLAN

Standards, Security and Security Stds,

Configuration and Deployment

Network Security Device Security, Security Features 1 1

WAN

Implementing WAN Links, Troubleshooting,

VPN technology 1

IP Services 2

Establishing N/W 2

Hardware N/W:

N/W device configuration: Router, Switches, Gateway, Cables 2

Port types (USB, PS/2, etc.) 1

Memory types (DDR2, SDRAM, etc.) 1

Basic architecture: bus, master-slave, etc 1 1

Motherboard components: processor, CMOS, slots, etc. 1 1

External hardware: printers, scanners connecting these to networks 1

Troubleshooting hardware errors 2

Linux:

Installing Linux server 2

Filesystem and Partitions (ext2, ext3, swap, boot, etc) 1

Basic knowledge of Linux types (Debian, Redhat, KDE, GNOME, etc) 1 1

Linux Commands: ls, mkdir, piping, grep, awk etc. Usage of commands (not syntax based questions) 2

Concept of kernels and processes 1 1

Configuring network on Linux 2

Creating and Managing User accounts, admin account 1

Installing and Updating Software 1

Installing and Configuring Network Services (http, ftp, ssh, smtp, imap, etc.) 2

Linux security 2

3 14

Windows Windows Server 2003Managing and Maintaining Physical and Logical Devices and Access to

Resources 1

Managing Users, Computers, and Groups 1Managing Server Environment: (Print queues, disk quotas, system

performance) 2Designing, Implementing and Managing Network (Topology, IPs, DNS, Routing,

etc.) 2Designing, Implementing and Managing Network security (Firewall, public key,

access control, etc.) 2

Monitoring and Troubleshooting Network 2Planning and Implementing an Active Directory Infrastructure (User and Group

Policies) 1

Windows Client

Installing Windows 1

Administration of Windows (all versions), Installation of Software, Registry 1

Troubleshooting device and driver 2

Troubleshooting Windows problem: Virus, BSOD, Worm etc. 2

Security: Firewall, Anti-Virus, Spyware, Policies 2

Network Setting on XP: TCP/IP, Proxy Setting etc. 1

Managing and Maintaing Users 1

21

1


36/36

Total weightag

2

1

2

2

1

1

2

1

2

1

2

1

2

2

2

1

1

2

2

1

2

33

2

12

2

2

21

1

2

217

syllabus file

Documents