4.2 DISCUSSION

In this organoleptic test, semi-solid dosage form (ointment) are not too hard, yellowish-white and odorless. This test purpose is to to see the phase changes of semi-solid dosage forms

Homogeneity test is intended to determine the homogeneity of the active substance in the base, so that every time the experiment of ointment is used the same dose will be used. In addition, the homogeneity test is to see if there are drugs that are too coarse(big) particles which can irritate the skin. Homogeneity can also be influenced by fine milling is done at the time of manufacture. At this homogeneity test, formula ointment (chloramphenicol) showed a homogeneous(smooth) on glass objects, which is no seen or presence of the tiny particles that make ointment feels rough.

Leakage test is intended to determine a leak in the tube. At this lab former ointments packed in tubes that have been cleared through the bottom of the tube. In the test tube leak turns used leaked where absorbent paper used to be wet after a leak test. this is happen because the practicant is not a skilled practitioner in the former tube cleaning and unskilled in the folded tube which one of the cause of the leaking.

CHAPTER V

CONCLUSIONS AND SUGGESTIONS

5.1 Conclusions

Salep is perfomed half-solid form easily applied and used as an external medicine. Ointment base material is a hydrocarbon, where the basic ointment used are vaseline

album Chloramfenicol ointment experimental results meet the requirements by our group

5.2 Suggestions

When formulating a preparation of an ointment , practitioner should really pay attention to the characteristics of materials, the concentration of the material, and nature of each of the materials as well as the interaction between the material likely very common occurs. Thus , a formulated preparation will produce a preparation that is really safe and efficacy to use and to minimize reduce the shortcomings or weakness of the cream preparation.

Besides that , other factors to consider is the manufacturing process,. Taking into account which is the characteristics, concentration and interaction of each material when conducting and experiment . A practitioner must be able to design and create the best possible working procedure according to the provisions, so that preparations can be made to meet the standards of evaluation set.

Should be evaluated using other methods