stress and hormones - ptf & associates...10/12/2010 1 stress and hormones: making the connection...
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Stress and Hormones:Making the Connection
•Definition of stress/stressor
•Brain’s role in hormone regulationBrain s role in hormone regulation
•Steroid hormones and their jobs
•Case studies
Brain Body
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Brain – Body Communication Methods:
•Nerves•Blood•Hormones
PERFECT FUNCTION OR HOMEOSTASIS
THE BODY AT EASE
DIS‐EASE OR DYSFUNCTION
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Hormones
Brain: Pituitary and Hypothalamus
ANATOMY OF THE BRAIN
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Pituitary and Hypothalamus
Anterior Pituitary Stimulating Hormones
•Growth Hormone•Thyroid Stimulating Hormone•Adrenocorticotropic Hormone•Adrenocorticotropic Hormone•Follicle‐Stimulating Hormone•Luteinizing Hormone•Prolactin
Ant. PituitaryHormone
Major Target
Organ(s)Major
Physiological Effects
Growth Hormone(HGH)
Liver, adipose tissue
Promotes growth(indirectly),
Control of protein,lipid, and
carb. metabolismcarb. metabolism
Thyroid‐stimulating
Hormone (TSH)Thyroid Gland
Stimulates secretion of
thyroid hormones
Adrenocortico‐tropic
Hormone (ACTH)
Adrenal Gland(Cortex)
Stimulates secretion of
glucocorticoids
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Ant. PituitaryHormone
Major TargetOrgan(s)
MajorPhysiological
Effects
LuteinizingHormone
Ovary and TestisControl ofreproductivefunction
Follicle‐stimulating Hormone
Prolactin
Ovary and TestisControl of
reproductive function
Mammary GlandMilk
Production
Posterior Pituitary Hormones
•Antidiuretic Hormone•Oxytocin
Post. PituitaryHormone
Major Target Organ(s)
MajorPhysiological
Effects
AntidiureticHormone
KidneyConservation of
Body fluid
Oxytocin Mammary, Ovary and Testis
Stimulates milk ejection, uterine contractions,establishes maternal behavior
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THE POWER BEHIND THE THRONE
.
Hypothalamus Pituitary
FSH and LHhGH
TSH
ACTH
Others
Endocrine Relationships
M e d u lla
C o r te x
P i tu i ta r y
P a n c re a s
D u o d e n u m
A d r e n a ls
F o llic le
C o r p o r a L u te a
P la c e n ta
P a r a -T h y r o id
G o n a d s
T h y m u s
L ive r T h y r o id P in e a l
M a m m a e
C o o p e r a t io n A n ta g o n is m
Excerpt from Harrowers “Excerpt from Harrowers “Endocrinology”Endocrinology”
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Major Players
Medulla
Cortex
Pituitary
Pancreas
Duodenum
Adrenals AdrenalsPituitary
Follicle
Corpora Lutea
Placenta
Para-Thyroid
Gonads
Thymus
Liver Thyroid Pineal
Mammae
Cooperation Antagonism
Excerpt from Harrowers “Excerpt from Harrowers “Endocrinology”Endocrinology”
Thyroid
Sex Organs
Functions of Hormones
1.) Help Regulate:
‐ Metabolism and energy balance
‐ Biological clock (circadium rhythm)
‐ Glandular secretions
‐ Some immune activities
Functions of Hormones (cont.)
2.) Control growth and development
3.) Govern reproduction
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•Controls rate at which bodyproduces energy
•Controls body temperature
Thyroid
y p
•Affects mood
•Impacts immunity
Adrenal Glands
The Adrenals
Four basic hormonal functions:•Glucocorticoids regulate blood sugar and inflammation
An important part of the “fight or flight” h imechanism
•Mineralocorticoids regulate mineral balance, particularly sodium and potassium
•DHEA production – our ‘anti‐aging hormone’Production of sex hormones
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FUNCTIONS OF CORTISOL
•Literally can’t live without it•Mobilizes and increases amino acids•Boosts energy levelsI di ti•Improves digestion
•Eases joint movement•Lessens inflammation and pain•Enhances immune function•Maintains personality and emotional stability
FUNCTIONS OF DHEA
•Increases muscle mass; decreases body fat•Improves cardiovascular function
•Enhances immune systemEnhances immune system
•Helps prevent decreased mental function
•Helps fat loss; increases lean body mass
•Stimulates new bone growth
• Ovaries produce the female sex hormones: estrogens and progesterone in cycling
Sex Organs
women.
• Testes produce the primary male sex hormone, testosterone.
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DIS‐EASE OR DYSFUNCTION
Stressors
• Poor Diet• Mental/Emotional/• Physical• Biochemical
DIETARY STRESSORS
•Poor nutrient intake = bad fuel
•S.A.D. can lead to gut issues
•Caffeine/alcohol overuse
•High carb = glycemic/adrenal issues
•Food allergies/intolerances
•Insufficient protein can createneurotransmitter deficiencies
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MENTAL STRESSORS
•Work overload • Late hoursSl d i i•Sleep deprivation
•Financial worries• Unfulfilling life •Negative thoughts
MENTAL STRESSORS
EMOTIONAL STRESSORS
Death of loved one DivorceJob Loss AngergUnfulfilling relationships GuiltFearfulness LonelinessNot feeling heard Not having fun
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PHYSICAL STRESSORS
•Trauma or illness•Lack of exercise•Excessive physical exertionp y•Whiplash and Subluxations•Surgery•Chronic pain•Lack of relaxation
BIOCHEMICAL STRESSORS
Liver overload AllergiesDysbiosis MoldsI f ti I fl tiInfection InflammationXenobiotics EMFsAnemia Malabsorption
SYMPTOMS OF ADRENAL DYSFUNCTION
•Hypoglycemia•Cravings for sweets•Moments of confusion/Poor memory•Premenstrual tension•Weight control problems•Food and/or inhalant allergies•Poor resistance to infections
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Chief Complaints of Adrenal Insufficiency
•Excessive fatigue•Nervousness/Irritability•Mental Depressionp•Inability to concentrate•Apprehension•Light‐headedness•Insomnia
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ADRENAL/THYROID CONNECTION
Low thyroid function is usually secondary to
adrenal stress!
Case StudiesCase Studies
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Are hidden t ff ti
Think About It:
stressors affecting your life?
Thank you!
Anne Fischer Silva, CN, FDN, ,A New Leaf Nutrition