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Straumann® Biomaterials> Biologics
Straumann® Emdogain® FLCultivating periodontal regeneration.
PATIENT COMFORT
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2 Straumann® Emdogain® FL Straumann® Emdogain® FL
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INCREASE PATIENT COMFORTRender your procedures milder
and more tolerable.
MORE EFFICIENTAchieve results comparable to
periodontal flap surgery.
MORE EFFECTIVEEliminate more pockets.
Differentiate your practice by offering a flapless regenerative periodontal treatment with Straumann® Emdogain® FL.
For the first time, true periodontal re-generation can be achieved in a mini-mally invasive way: without surgical flap.Based on decades of clinical experience in regenerative flap surgery periodontal pockets up to 9 mm deep can now be regenerated and eliminated as part of flapless periodontal procedures with Emdogain® FL.
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Adding Emdogain® FL to a flapless periodontal pro- cedure* can help you to eliminate more pockets, have more efficient procedures and improve the quality of life for your patients.
ѹ Render your procedures more efficient with clinical results comparable to periodontal surgery
ѹ Similar clinical results as when Emdogain® is applied with a flap surgery after 12 and 24 months²
6
4
2
0
8
Baseline 12 months 24 months
PPD
(mm
)
FlaplessMinimally invasive surgery
60%
50%54%
40%
30%31%
20%
10%
0%
80%
90%
70%
100%
SRP alone SRP with Emdogain® FL
Patie
nts w
ithou
t pai
n or
dis
com
fort
(1 w
eek
afte
r SRP
)
60%
50%42%
40%
30%
11%20%
10%
80%
90%
70%
100%
SRP alone SRP with Emdogain® FL
Reso
lved
cas
es a
t 3 m
onth
s (pa
tient
s pr
esen
ting
no p
ocke
ts w
ith P
PD ≥
6m
m)⁶
0%
ѹ Eliminate more pockets and render your procedures more effective
ѹ Significantly improved clinical results¹
0%
10%
20%
30%
40%
50%
60%
70%
80%
6 months3 months 12 months
% o
f elim
inat
ed p
ocke
ts
with
PPD
> 5
mm
SRP alone SRP with Emdogain® FL
76%
63%64%
79%81%
66%
ѹ Improve the quality of life of patients by reducing pain, swelling and systemic inflammation
ѹ Faster patient3 recovery
Less surgeriesLess pain
ѹ True periodontal regeneration as evidenced by the formation of new cementum, new periodontal ligament and new bone in pre- clinical4 and clinical5 histological studies
* as described in the instructions for use for Emdogain® FL available at ifu.straumann.com
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Left frontal incisor before treatment PPD = 1 – 2 mm3 years after treatment with Straumann® Emdogain® FL
3 YEAR RESULTS AFTER FLAPLESS PERIODONTAL REGENERATION WITH EMDOGAIN® FL
Pictures with courtesy of Dr. Orest G Komarnyckyj DDS, Phoenix AZ, USA
PPD ≥ 9mm
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Straumann® Emdogain® FL leads to true periodontal regeneration based on biomimicry. Emdogain® FL contains enamel matrix derivative – the active natural protein matrix responsible for tooth formation. When applied to cleaned tooth root surfaces the unique protein composition in Straumann Emdogain® FL is able to induce the regeneration of all periodontal tissues: gingiva, cementum, periodontal ligament and alveolar bone.
Straumann® Emdogain® FL – 20 years of research and clinical experience in periodontal pockets.
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Contact your local Straumann representative now or visit www.straumann.com.
Article number Product name Contents
075.130 Emdogain® FL 0.15 ml 1× Emdogain® FL 0.15 ml1× PrefGel® 0.6 ml2× cannulas for flapless use
075.131 Emdogain® FL 0.3 ml 1× Emdogain® FL 0.3 ml1× PrefGel® 0.6 ml2× cannulas for flapless use
Straumann® Emdogain® FL is available in two product sizes for the flapless regenerative periodontal treatment of single or multiple pockets.
AVAILABLE IN THE FOLLOWING SIZES
STRAUMANN® EMDOGAIN® IN FACTS AND FIGURES
* Based on the number of syringes sold to date, globally
** According to PUBMED search for “Emdogain” or “enamel matrix derivative”
*** Based on a global post-surgical complication rate of less than 0.002 %
> 20 yearson the market
> 2 million patients treated*
> 600 clinical & 1,000 scientific
publications**
Extremely well tolerated***
Stable results
documentedover 10 years in 2 indications
Straumann® Emdogain® is the gold standard for the safe and predictable regeneration of periodontal tissues lost as part of periodontitis or trauma. Based on the foundation of long-term clinical experience, the unique regenerative properties of the product have now been used to develop Emdogain® FL to regenerate and help save teeth as part of flapless peri- odontal procedures.
STRAUMANN® EMDOGAIN® FL – BASED ON A STRONG FOUNDATION
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With Emdogain® FL periodontal regeneration can be achieved in a minimally invasive way: without surgical flap.• Effective: renders procedures more effective and eliminates
more pockets as part of periodontal debridement procedures• Efficient: renders procedures more efficient and acceptable
by achieving results comparable to periodontal flap surgery• Patient comfort: improves patient satisfaction and renders
procedures more tolerable by reducing pain, swelling and systemic inflammation
Straumann® Emdogain® FL
REFERENCES
1 Straumann Sponsored Study (data on file, study ongoing). 2 Aimetti M, Ferrarotti F, Mariani GM, Romano F. A novel flapless approach versus minimally invasive surgery in periodontal regeneration with enamel matrix de-rivative proteins: a 24-month randomized controlled clinical trial. Clin Oral Investig. 2017 Jan;21(1):327-337. 3 Wennström JL, Lindhe J. Some effects of enamel matrix proteins on wound healing in the dento-gingival region. J Clin Periodontol. 2002 Jan;29(1):9-14. 4 Shujaa Addin A, Akizuki T, Matsuura T, Hoshi S, Ikawa T, Maruyama K, Ono W, Fukuba S, Izumi Y. Histological healing after nonsurgical periodontal treatment with enamel ma-trix derivatives in canine experimental periodontitis. Odontology. 2018 Jul;106(3):289-296. 5 Mellonig JT, Valderrama P, Gregory HJ, Cochran DL. Clinical and histologic evaluation of non-surgical periodontal therapy with enamel matrix derivative: a report of four cases. J Periodontol. 2009 Sep;80(9):1534-40. 6 Graziani F, Gennai S, Petrini M, Bettini L, Tonetti M. Enamel matrix derivative stabilizes blood clot and improves clinical healing in deep pockets after flapless periodontal therapy: A Randomized Clinical Trial. J Clin Periodontol. 2019 Feb;46(2):231-240.
International HeadquartersInstitut Straumann AGPeter Merian-Weg 12CH-4002 Basel, SwitzerlandPhone +41 (0)61 965 11 11Fax +41 (0)61 965 11 01 www.straumann.com
© Institut Straumann AG, 2019. All rights reserved.Straumann® and/or other trademarks and logos from Straumann® mentioned herein are the trademarks or registered trademarks of Straumann Holding AG and/or its affiliates.
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