steph garfield-birkbeck assistant director nihr evaluation trials and studies coordinating centre,...
TRANSCRIPT
Steph Garfield-BirkbeckAssistant Director
NIHR Evaluation Trials and Studies Coordinating Centre, University of Southampton
The NIHR Health Research System
www.nihr.ac.uk
• Research with the capacity to improve patient outcomes and NHS services
• Clinical research (not only trials)
• Not– Discovery science– Animal
• What is Applied Research?
www.nihr.ac.uk
NETSCC: Established: 2008
NIHR Evaluation, Trials and Studies (NETS) programmes - from 2012
Health Technology Assessment
Established: 1993
Health Services and Delivery Research
Established: January 2012
Public Health Research
Established: 2008
Efficacy and Mechanism Evaluation
Funded by the MRC and NIHR, managed by NIHR
Established: 2008
Systematic Review
Established: 2012(previously known as Reviews Infrastructure)
HS&DR
SR
EME
PHRHTA
www.nihr.ac.uk
Science Added• The secretariat adds value to
the research progress through– Clinical and
methodological input– Steering prioritisation– dissemination
• Projects are funded on the basis of the needs of the health service– Not the scientific interest
of the project
Needs Led
• Programme Characteristics
www.nihr.ac.uk
Researcher Led
• Open calls for researchers to apply for funding for their own topics and questions
• Applications are prioritised in terms of NHS or other information needs
• Starts with the information needs of decision makers
• Topics are refined and prioritised by people with expertise in the field, and commissioning briefs are advertised
Commissioned
• Workstreams
All applications assesses against the same ‘needs’ and ‘quality’ standards
www.nihr.ac.uk
www.nihr.ac.uk
www.nihr.ac.uk
Research themes
Technology evaluation
Health services and
organisation
Public health
EME X X
HS&DR X X
HTA X X X
PHR X
SR X X X
www.nihr.ac.uk
Which NIHR Research Programme
• i4i – translational R&D projects aimed at cultivating new techniques or technologies into innovative interventions to address healthcare needs www.ccf.nihr.ac.uk/i4i
• EME – exploratory trials, less pragmatic, phase 2-3, efficacy, mechanisms if possible www.eme.ac.uk
• HTA – systematic reviews, large multicentre pragmatic trials or other studies (phase 3-4), effectiveness in the NHS www.hta.ac.uk
• HS&DR – organisational, patient experience and access to services, qualitative or other www.netscc.ac.uk/hsdr
• PHR - evaluates public health interventions www.phr.ac.uk
• PGfAR – a broad range of interlinking health services research projects, generating a variety of outputs. www.ccf.nihr.ac.uk/PGfAR
• RfPB – max £350k for up to three years, awards made to NHS bodies www.ccf.nihr.ac.uk/RfPB
• Fellowships – doctoral, postdoctoral and senior fellowships www.nkhrtcc.nhs.uk/nihrfellow
www.nihr.ac.uk
What makes a good research question
• Important to the NHS and its patients• Supported by current evidence• High scientific quality• Feasible• Timely, i.e. research will continue to be relevant following
completion of study• Clear and well-defined• Represents value for money
www.nihr.ac.uk
Burden of disease
Health services
Need = frequency x severity x impact of technology x evidence deficit
(Discounted for time to produce evidence)
Important question on an important topic
Evidence gap
Prioritising research
www.nihr.ac.uk
Application assessment process: Generally a two-stage process
Outline proposals:►Remit and competitiveness check (pre-panel/board)►Panel assessment primarily for need and importance to the NHS►Shortlist/Reject/Resubmit
Full proposals:►External review►Board assessment primarily for scientific quality, value for money►Fund/Fund With Changes/Reject/Resubmit
One stage straight to full proposal process - option for researcher-led evidence synthesis submissions in some programmes
www.nihr.ac.uk
Selection criteria: Importance of the Research
►Adherence to the advertised commissioning brief or call specification
►Health need
►Expressed need
►Sustained interest
►Capacity to generate new knowledge
►Actionable findings and prospects for change
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Selection criteria: Research Quality
►Scientific quality
►Links with knowledge users and where appropriate, integration of knowledge users in the knowledge production process
►Service user involvement
► Make up of team and project management
► Value for money
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Hints and Tips for a good application (1)
• Is the Question Important
• Is it the Right Method
• Is the Research Feasible
• The Science
• Is the proposal clear, logical and persuasive
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Hints and Tips for a good application (2)
• The Team and Support
• Patient and Public Involvement
• Dissemination
• Costings
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Sources of information and help
• NIHR Clinical Research Network
• Research Design Service (RDS)
• INVOLVE
• Browse NETS website for study protocols, guidance notes and FAQs
• Become a reviewer for NETS programmes
• Become a panel member
www.nihr.ac.uk
Keeping in touch:
The NIHR: http://www.nihr.ac.uk
Trainees Coordinating [email protected]
Steph [email protected]