SOUTH AFRICAN PROBIOTICS

INDUSTRY LANDSCAPE REPORT

PUBLISHED: SEPTEMBER 2020

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HEALTHCARE INDUSTRY REPORT CLIENTS

SOME KEY QUESTIONS THE REPORT WILL HELP YOU TO ANSWER:

For the Global Probiotics Industry Section:

o What are the current market dynamics of the global Probiotics industry?

o What are the key markets within the global Probiotics industry?

o What are the global Probiotics industry trends, innovations and technologies, drivers, and challenges?

For the South African Probiotics Industry Section:

o What are the current market dynamics (market size, market value, market volumes): 2014-2019 Actual, 2020-2024 Forecasts (including the impact of COVID-19), distribution

channels?

o What are the South African Probiotics industry trends, innovations and technologies, drivers, and challenges?

For the South African Probiotics Manufacturer & Distributor Section:

o Who are the key manufacturing players and distributors in the South African Probiotics industry?

o Which popular Probiotics brands and products do the respective companies manufacture/distribute?

For the South African Probiotics Retail and Pricing Analysis Section:

o Who are the key retail players (retail pharmacies, in-store retail pharmacies) in the South African Probiotics industry?

o What are the prices of popular Probiotics brands across South African retail outlets?

The South African Probiotics Industry Landscape Report (98 pages) provides a dynamic synthesis of industry research, examining the local

and global Probiotics industry (including the impact of COVID-19) from a uniquely holistic perspective, with detailed insights into the entire

value chain – from manufacturing to retailing, market size trends, industry trends, innovation and technology, industry drivers and challenges,

and pricing analysis.

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REPORT OVERVIEW

98-page report filled with detailed charts, graphs, and insights

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SCREENSHOTS FROM REPORT

The global Probiotic Dietary Supplement market was valued

at approximately US$3.2 billion in 2019, and is predicted to

grow at a CAGR of 8.1% to reach approximately US$4.7

billion in 2024*, as illustrated in the adjacent graph.

o Growth of the global Probiotic Dietary Supplement market is being driven

by the demand for health-based products amongst consumers worldwide,

particularly amongst younger generations. Accordingly, Probiotic Dietary

Supplements are becoming increasingly popular as a result of their

associated health benefits. Some of these benefits include boosting the

immune system, and improving gut functionality, amongst other potential

health benefits.

o Additionally, Probiotics are extending beyond simple digestive health, into

feminine, oral, and skin health, as well as weight control and diabetes,

cognitive health, sports endurance, and cardiovascular health.

o In particular, the growing number of health applications of Probiotics is

making these types of organisms one of the most versatile product

ingredients in history, as a result of their significant and wide-ranging

applications and potential health benefits offered to consumers.

o Furthermore, consumer awareness of Probiotics in terms of available

products and benefits, is resulting in growing willingness to try different

Probiotic delivery systems and formats. Accordingly, although dietary

supplement formats are likely to remain popular, enhanced delivery

systems that protect Probiotic strains and enhance delivery accuracy are

likely to increase in terms of importance.

o Interestingly, although the COVID-19 lockdowns have disrupted the global

economy, and consumer spending power, revenue growth of Probiotic

Dietary Supplements has continued to rise. This is due to the desire of

consumers to look for ways of strengthening their immune system.

o However, market growth could be constrained by ongoing challenges in

terms of regulation and approval of Probiotic containing products in many

markets globally, limiting the release of newer products.

o The global Probiotic Supplements market can be segmented according to

source into lactobacillus, bifidobacterium, saccharomyces boulardii, and

others. In 2019, lactobacillus dominated the market due to the range of

health benefits offered by this strain, including reducing cholesterol,

preventing diarrhoea, and weight loss, amongst others.

2020 | 7Source: MordorIntelligence; GlobeNewsWire; PRNewsWire; Image

SAMPLE FROM REPORTGLOBAL INDUSTRY OVERVIEW: PROBIOTICS

3.2

4.7

0

1

2

3

4

5

2019 2024*

VALUE OF THE GLOBAL PROBIOTIC DIETARY SUPPLEMENT MARKET: 2019 VS 2024* (IN US$ BILLION)

* Estimate

Tailored Probiotics Become Increasingly Popular

o South African consumers are increasingly seeking out Probiotic

supplements, with many manufacturers attempting to appeal to specific

market segments, by creating products designed to meet the needs of

specific groups. These include Probiotics specifically designed for women,

those attempting to lose weight, and those with an active lifestyle, along

with a variety of other target-specific Probiotics.

o For example, a variety of Probiotics are currently available in South Africa,

which are specifically designed to meet the needs of female consumers.

These include ProVen Probiotics for Women, MiBiotix Women VG, and

Reuterina Femme products. In addition, MiBiotix also offers MiBiotix

Prenatal PN, a Probiotic supplement that is specially designed to meet the

needs of pregnant women.

o In addition, several Probiotic products claiming to aid in weight loss are

also available. These include ProVen’s 50 Billion-ShapeLine, which claims

to be the first human microflora product shown to support a ‘shapelier

you’, as well as MiBiotix Shape, which claims to aid in reducing weight

gain resulting from disturbances in the gut lining.

o Furthermore, for those who engage in an active lifestyle, MiBiotix offers its

MiBiotix Active AC product, which offers athletes secondary health

benefits that may improve performance and wellbeing. This focus on

athletes is also seen in the Probiotics ranges of Sports nutrition and

wellness companies, such as GNC, which offers several Probiotic

products targeted to meet the needs of their active consumers.

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SAMPLE FROM REPORTSA INDUSTRY TRENDS

o Moreover, the MiBiotix brand includes a variety of products targeted at

specific individuals, health issues and life stages. These include products

designed for seniors (50+), children and babies, those on antibiotic

therapies, as well as those affected by various issues, such as heart and

immune health, or moods and stress, amongst others.

o As more consumers begin to seek out and make use of Probiotic

supplements, more manufacturers are developing a wider range of

Probiotic products to appeal to the needs and concerns of individual

consumers. As such, individual-focused Probiotic products are likely to

continue to trend in 2020.

Source: ProVen; MiBiWomen; Reuterina; MiBiPeg; ShapeLine; MiBShape; MiBiActive; GNC1; GNC2

BOS Launches Probiotic Wellness Shot

o As consumers become increasingly aware of the importance of digestive

health, many are seeking out new and varied Probiotic products. One

such example is the BOS ‘Gut a Problem?’ Probiotic Rooibos Shot, which

was launched in March 2020.

o This product promotes gut health through a combination of rooibos, grape

juice, apple cider vinegar, and added Probiotics, specifically Bacillus

coagulan. Bacillus coagulan is a Probiotic strain that is linked to the relief

of abdominal pain, bloating, intestinal gas, and diarrhoea. Each shot

contains 1 billion colony forming units (CFU) of Bacillus coagulans, which

is the recommended daily dose that is needed to support gut health and is

double the amount needed to support the immune system.

o In addition, the rooibos and grape juices used in the product have also

been linked to various Prebiotic qualities. The antioxidants found in

rooibos act as a Prebiotic, stimulating the growth of beneficial gut

bacteria, as well as having a calming effect on the digestive system.

o Moreover, the grape juice used is rich in resveratrol, a polyphenol that

stimulates the growth of beneficial bacteria and inhibits the growth of

pathogenic bacteria, as well as acting as a Prebiotic in the gut.

o Furthermore, the inclusion of Prebiotics and Probiotics makes the BOS

Probiotic Shot particularly beneficial. This is due to the co-ingestion of

Prebiotics and Probiotics being linked to increasing levels of beneficial

bacteria, as well as the increase in organic acids, which reduce the

colonisation of pathogenic bacteria.

2020 | 9Source: SouthAfrican; BOSFB; BOS

SAMPLE FROM REPORTSA INDUSTRY INNOVATION AND TECHNOLOGY

o As such, BOS Rooibos Probiotic Shot offers consumers an easy, effective

and tasty way to boost their digestive health, through the use of both

Prebiotics and Probiotics. Additionally, BOS’ brand recognition may result

in consumers feeling more familiar with the product.

2020 | 10Source: Bestum; Lp299v; ProbiFlora; Classic; Balance; InfantDrops; Rescue; Junior; Rx

SAMPLE FROM REPORT ADCOCK INGRAM: PROBIOTIC BRANDS/PRODUCTS

BRAND/PRODUCT IMAGE DESCRIPTION

Bestum

A multi-nutrient supplement containing Probiotics, minerals, vitamins, anti-oxidants, as well as herbal extracts.

This product is designed to support overall well-being and health and is available in pack sizes of 30 and 60

tablets.

Lp299v

A Probiotic that contains the beneficial bacteria called Lactobacillus plantarum 299v. This bacteria is used to

reduce harmful microbial balance in the human intestines and thereby improves the functioning of the digestive

tract/gut and avoids the production of harmful toxins in the body. This product is available in pack sizes of 20 and

60 capsules.

ProbiFlora

A range of Probiotics designed to improve and normalise microbial balance in the human intestines, which helps

to improve the functioning of the digestive tract or gut. The ProbiFlora range is available in the following variants:

✓ ProbiFlora Adult Classic Bowel Support: A four strain Probiotic, containing four common Probiotic strains,

that supports overall intestinal health and bowel function. This product is available in pack sizes of 30 and 60

vegecaps.

✓ ProbiFlora Adult Everyday Flora Balance: A two strain Probiotic designed to support micro flora balance, gut

health, and good digestive functioning. This product is available in pack sizes of 30 vegecaps.

✓ ProbiFlora Infant Drops: A three strain Probiotic designed to improve and normalise the microbial balance in

the intestines of infants. This product is available in pack sizes of 5ml bottles.

✓ ProbiFlora Adult Intensive Rescue: A nine strain Probiotic designed to improve intestinal health in adults.

This product is available in pack sizes of 30 and 60 capsules.

✓ ProbiFlora Junior Everyday Flora Balance: A three strain Probiotic designed to restore and maintain delicate

intestinal flora in children. This product also aims to aid with immune functioning, gut health, food allergies, and

lactose intolerance. This product is available in pack sizes of 30 chewable tablets.

✓ ProbiFlora Rx: A Probiotic supplement designed to maintain and restore the intestinal flora balance in

individuals who are on antibiotic treatment. This product is available in pack sizes of 10 vegecaps.

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SAMPLE FROM REPORTPROBIOTICS PRICING ANALYSIS

BRAND AND SIZE

Créche Guard Complete

Probiotic Spray20ml Spray N/A R136.95 N/A N/A

Daily Flora Capsules 30 Capsules N/A R249.95 N/A N/A

Daily Flora Powder 50g Powder N/A R519.95 N/A N/A

Entiro Melt 10 Sachets R71.99 (Special) R85.95 N/A R89.00

Entiro Probiotic

10 Capsules R49.99 (Special) R61.95 R69.90 R59.99

10 Chewable Tablets R59.99 (Special) R69.95 R90.00 R69.99

GastroChoice IBS 30 Capsules R 220.00 R199.95 N/A R191.99

GastroChoice Probiotic 30 Capsules R 180.00 R164.95 N/A R191.99

This pricing analysis was conducted at pharmacies during w/c 31 August 2020.

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TABLE OF CONTENTS

EXECUTIVE SUMMARY (3 Pages)

Global Industry Snapshot

South African Industry Snapshot

South African Industry Drivers and Challenges

1. GLOBAL PROBIOTICS INDUSTRY (21 Pages)

1.1 Global Industry Overview: Digestive Remedies: VALUE OF THE GLOBAL DIGESTIVE REMEDIES MARKET: 2019 VS 2024* (IN US$ BILLION) (Graph)

1.2 Global Industry Overview: Probiotics: VALUE OF THE GLOBAL PROBIOTIC DIETARY SUPPLEMENT MARKET: 2019 VS 2024* (IN US$ BILLION) (Graph)

1.3 Global Industry Overview: Prebiotics: VALUE OF THE GLOBAL PREBIOTIC INGREDIENTS MARKET: 2019 VS 2024* (IN US$ BILLION) (Graph)

1.4 Global Industry Overview: Digestive Enzymes: VALUE OF THE GLOBAL DIGESTIVE ENZYMES MARKET: 2019 VS 2024* (IN US$ MILLION) (Graph)

1.5 Global Market Environment: Probiotics

1.6 Global Market Environment: Prebiotics

1.7 Global Market Environment: Digestive Enzymes

1.8 Global Key Markets: Regional Overview: GLOBAL DIGESTIVE REMEDIES RETAIL SALES, BY REGION: 2019 (IN US$ MILLION) (Graph)

1.9 Global Industry Trends

1.10 Global Industry Innovation And Technology

1.11 Global Industry Drivers

1.12 Global Industry Challenges

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TABLE OF CONTENTS

2. SOUTH AFRICAN PROBIOTICS INDUSTRY (21 Pages)

2.1 South African Industry Overview

2.2 South African Market Environment

2.3 South African Industry Market: South African Probiotic Supplements Market Definitions

2.4 South African Industry Market: South African Probiotic Supplements Distribution Definitions

2.5 South African Industry Market Size: Probiotic Supplements Market (2014-2019): VALUE OF SA PROBIOTIC SUPPLEMENTS MARKET: 2014-2019 (IN ZAR

MILLION); SA PROBIOTIC SUPPLEMENTS MARKET CAGR AND TOTAL GROWTH (IN PERCENTAGE) (Graph and Table)

2.6 South African Industry Market Size: Probiotic Supplements Market (2014-2019: By Category): VALUE OF SA DIETARY SUPPLEMENTS MARKET BY CATEGORY:

2014-2019 (IN ZAR MILLION) (Graph)

2.7 South African Industry Market Size Forecast And Volumes: Probiotic Supplements Market (Forecast: 2020*-2024*; Volumes: 2014-2024*): VALUE OF SA

PROBIOTIC SUPPLEMENTS MARKET: 2019 & 2024* (IN ZAR MILLION); SA PROBIOTIC SUPPLEMENTS MARKET VALUE FORECAST BY CATEGORY (IN ZAR

MILLION); RETAIL VOLUME OF SA PROBIOTIC SUPPLEMENTS MARKET (2014-2024*) (Graph and Tables)

2.8 South African Industry Market Distribution: Probiotic Supplements Market: CHANNEL DISTRIBUTION FOR VITAMINS AND DIETARY SUPPLEMENT PRODUCTS:

2019 (IN PERCENTAGE); CHANNEL DISTRIBUTION (2014 AND 2019) BY OUTLET TYPE (Graph and Table)

2.9 South African Industry Trends

2.10 South African Industry Innovation and Technology

2.11 South African Industry Drivers

2.12 South African Industry Challenges

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TABLE OF CONTENTS

3. SOUTH AFRICAN PROBIOTICS MANUFACTURER & DISTRIBUTOR OVERVIEW (20 Pages)

3.1 Adcock Ingram: Overview

3.2 Adcock Ingram: Probiotic Brands/Products

3.3 Amipro: Overview

3.4 Amipro: Probiotic Brands/Products

3.5 Ascendis Health: Overview

3.6 Ascendis Health: Probiotic Brands/Products

3.7 Cipla Medpro: Overview

3.8 Cipla Medpro: Probiotic Brands/Products

3.9 iNova Pharmaceuticals: Overview

3.10 iNova Pharmaceuticals: Probiotic Brands/Products

3.11 Nativa: Overview

3.12 Nativa: Probiotic Brands/Products

3.13 SA Natural Products (Pty) Ltd (A.Vogel): Overview and Prebiotic Brands/Products

3.14 Sanofi: Overview

3.15 Sanofi: Probiotic Brands/Products

3.16 South African Probiotic Manufacturers and Distributors: Other

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TABLE OF CONTENTS

4. SOUTH AFRICAN PROBIOTICS RETAIL & PRICING ANALYSIS (19 Pages)

4.1 SOUTH AFRICAN PROBIOTICS RETAIL OVERVIEW (2 Pages)

4.1.1 South African Retail Overview: NUMBER OF STORES PER PHARMACY: 2020 (Graph); PROBIOTICS PRODUCT PRICE ANALYSIS 2020 (Table)

4.2 SOUTH AFRICAN PROBIOTICS PHARMACIES (5 Pages)

4.2.1 Clicks: Overview

4.2.2 Dis-Chem: Overview

4.2.3 Medicare: Overview

4.2.4 Other South African Retailers

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TABLE OF CONTENTS

4. SOUTH AFRICAN PROBIOTICS RETAIL & PRICING ANALYSIS (CONTINUED) (19 Pages)

4.3 SOUTH AFRICAN PROBIOTICS PRICING ANALYSIS (12 Pages)

4.3.1 Probiotics Pricing Analysis: Prebiotics- A.Vogel Molkosan; GNC Prebiotic GOS

- Comparative pricing at Clicks, Dis-Chem, MediRite Pharmacy, and Pick n Pay Pharmacy

4.3.2 Probiotics Pricing Analysis: Probiotics- Bestum, Supreme Probiotic 9-Strain, Biogen Probiotic Drops, Clicks Probiotic Paediatric Drops, Clicks Saccharomyces

Boulardii Supplement, Créche Guard Baby Probiotic Skin Spray, Créche Guard Baby Probiotic MultiVit Spray, Créche Guard Baby Complete Probiotic Drops,

Créche Guard Complete Probiotic Spray, Daily Flora Capsules, Daily Flora Powder, Entiro Melt, Entiro, Probiotic, GastroChoice IBS, GastroChoice Probiotic,

GNC Probiotic, GNC Probiotic Complex, Housebrand 9-Strain Probiotic, HydraChoice Probiotics Naartjie, Lacteol Forte, Lactovita, Lp299v, MetaKids Baby

Probiotic, MetaKids Probiotic, MiBiotix Daily, MiBiotix Kids, MiBiotix PreNatel, MiBiotix Shape, Nativa Complex Junior Probiotic Choco Buttons, Nature's Choice

Ultimate Probiotic, Pro-B5 Adult, Pro-B5 Junior, Pro-B5, Pro-B6 Suspension for Kids , ProbiFlora Adult Classic Bowel Support, ProbiFlora Adult Everyday Flora

Balance, ProbiFlora Infant Drops, ProbiFlora Adult Intensive Rescue, ProbiFlora Junior Everyday Flora Balance, ProbiFlora Rx, ProVen Acidophilus & Bifidus

with A-Z Multivitamins for Children , ProVen Adult Acidophilus & Bifidus – 25 Billion , Releaf Probiotic 12-strain, Releaf Probiotic Active, Releaf Probiotic Kids

Chews, Reuterina Acute, Reuterina Daily, Reuterina Femme, Reuterina Drops, Reuterina Junior, Reuterina VitD, Solal Mastic Gum, Solal Probiotic Maximum

Potency, Spasmopep Digest, Trubiotic, Ultima Probiotics Plus, UltraFlora Women’s, Vivomixx Micro 10bn, Vivomixx Probiotic 112bn, Vivomixx Probiotic - Comparative pricing at Clicks, Dis-Chem, MediRite Pharmacy, and Pick n Pay Pharmacy

4.3.3 Probiotics Pricing Analysis: Digestive Enzymes- Biogen Platinum Digestive Enzyme, Créche Guard Digest Eeze Drops, Dis-Chem Gold Digestive Enzymes,

Digestizyme, GNC Natural Digestive, Nativa Digestive Complex Capsule- Comparative pricing at Clicks, Dis-Chem, MediRite Pharmacy, and Pick n Pay Pharmacy

4.3.4 Probiotics Promotions: Clicks

4.3.5 Probiotics Promotions: Dis-Chem

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