sources of medical knowledge (1 october 2012)

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Joost Daams, MA Medical Information Specialist AMC medical library 1 October 2012 Resources of scientific knowledge: the weight of where to search

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Page 1: Sources of medical knowledge (1 october 2012)

Joost Daams, MAMedical Information Specialist

AMC medical library1 October 2012

Resources of scientific knowledge:

the weight of where to search

Page 2: Sources of medical knowledge (1 october 2012)

Introduction

… of WHERE to search:

• Internet as resource of medical information

• Journals & articles

• Books & point of care tools

• Catalogs & digital library

• Bibliographic databases

• Guidelines & other resources of evidence

The weight…

Page 3: Sources of medical knowledge (1 october 2012)

The weight of WHERE to search …(…HOW to search is a different chapter ☺)

• Integrity• transparency• reproducibillity (validity)

Lack of face validity:the curious case of “meat bastards”

… and evidence

Presentator
Presentatienotities
Hyperlink naar artikel op joop.nl van 25 augustus 2011 over “vleeshufters”. Later bleek Diederik Stapel te hebben gefraudeerd (http://nos.nl/artikel/308864-fraude-hoogleraar-stapel-verbijsterend.html ) en kwam o.a. Vonk terug op eerdere uitspraken (http://nos.nl/artikel/270909-onderzoek-vleeshufters-frauduleus.html)
Page 4: Sources of medical knowledge (1 october 2012)

Internet as resource of medical information (1)

How physicians get information to diagnose and treat patients

Derived from: http://www.wolterskluwerhealth.com/News/Documents/White%20Papers/Wolters%20Kluwer%20Health%20Survey%20Executive%2

0Summary-Media.pdf, last consulted: 29th

September 2012

Page 5: Sources of medical knowledge (1 october 2012)

Internet as resource of medical information (2)

??????

What about:

• integrity• transparency• reproducibillity (validity)?

What about:

• content• relevance ranking• … and evidence?

Page 6: Sources of medical knowledge (1 october 2012)

Journals & articles (1)

The quality of a journal (≈

article) can be assessed by quality indicators:

1. Established reputation e.g. Radiology is considered to be the top journal among radiologists, regardless of other quality inidcators

2. “Scientometrics” e.g. Journal Impact Factor (JIF), Hirsch-Index, Web “

Sitations”

3. Peer-review (y/n)

4. ICMJE compliancy (y/n)e.g. ethical considerations in the conduct and reporting of research, guidelines for the publication process as wellas the editorial process

Presentator
Presentatienotities
Peer-review according to the ICMJE: “ Peer review is the critical assessment of manuscripts submitted to journals by experts who are not part of the editorial staff”
Page 7: Sources of medical knowledge (1 october 2012)

Journals & articles (2)

More on the Journal Impact Factor (JIF)

• What it is & application

Critique

Temporality biasGeographical/language biasTopicality biasIncentive for self-citationsRange of provided subject topicsAssignment of journals to topicsPoor adaptation of web downloads / web citationsNon-transparent journal inclusion criteria by Thomson ReutersMonolithic organisation

Strengths“

Impact factor is not a perfect tool to measure the quality of articles but there is nothing better and it has theadvantage of already being in existence and is, therefore, a good technique for scientific evaluation.(…) The use of impact factor as a measure of quality is widespread

because it fits well with the opinion we havein each field of the best journals in our speciality.”

(Hoeffel C. Journal Impact factors. Allergy. 1998;53;1225)

JIF2011

=

A/BA = the number of times articles published in 2009 and 2010 were cited by indexed journals during 2011.B = the total number of "citable items" published by that journal in 2009 and 2010. ("Citable items" are usually articles, reviews, proceedings, or notes; not editorials or Letters-to-the-Editor.)

Page 8: Sources of medical knowledge (1 october 2012)

Journals & articles (3)

More on the International Committee of Medical Journal Editors (ICMJE)

• What it is & application

Important (major?) achievement

“The ICMJE member journals will require, as a condition of consideration for publication in their journals,registration in a public trials registry”

• … however publication bias is poorly addressed“Editors should seriously consider for publication any carefully done study of an important question, relevant to theirreaders, whether the results for the primary of any additional outcome are statistically significant.”

Page 9: Sources of medical knowledge (1 october 2012)

Journals & articles (4)

Open Access (OA) : a (would-be) idealists’ dream?

What it is & application

Golden road or green road?exposure

• What it’s notA priori free access (from the authors’

point of view)Already out there for all disciplinesA priori (not) peer-reviewedAlways protective of author rights

• Does OA influence JIF?Further research is needed: only 1 study indicated increased downloads without a necessary influence on clinical practice, but:

•` Researchers in the sciences do not see access to the scientific literature as an especially important problem

Authors consider factors such as journal reputation and the absence of publication fees when deciding where to submit their work. In contrast, free access is not a significant

factor in their submission decissions.

(The impact of free access to the scientific literature: a review of recent research, Davis, Philip M. and Walters, William H. Journal of the Medical Library Association. 2011;99(3);208)

Page 10: Sources of medical knowledge (1 october 2012)

Making a “case” for books

Books & ‘point of care tools’

Can exposure to high concentration of toluene diisocyanate (TDI) cause cognitive impairments?

?

In summary, psychometric testing using the Wechsler memory scale (1945) has shown a selective memory defect for relatively long-term recall among the group of firemen who were clinically thought to

be still suffering from organic cerebral impairment four years after the fire.”

Neurological complications after a single severe exposure to toluene di-

isocyanate PAMELA M.LE QUESNE et al. British Journal of Industrial Medicine . 1976;33;72-78

?

Presentator
Presentatienotities
Incident: Hij werkt als opleggermonteur en keurmeester bij zijn huidige werkgever en kreeg in juli een trailer ter keuring aangeboden, die oorspronkelijk TDI bevatte. Zoals gebruikelijk zette hij deze op druk van 1 bar. Deze bleek niet schoon maar naar schatting ongeveer 40-50 liter TDI te bevatten. Verder bleek de tank op bepaalde punten enigszins te lekken. Hij vergat een slang aan te sluiten en toen hij de druk afliet, hoorde hij het product er uitspuiten. Hij herinnert zich dat hij op dat moment direct benauwd werd, een droge keel kreeg, pijn in de longen pijn in de rug, een hese stem. Daarbij zag hij sterretjes. Hij is toen opgenomen in het ziekenhuis, waar hij naar zeggen een aantal keren ene lage pols heeft gehad van minder dan 30 slagen per minuut. Hij werd overigens de dag erop weer uit het ziekenhuis ontslagen. Klachten: Desgevraagd meldt betrokkene last te hebben van geheugenklachten. Zo meldt hij zich belangrijke data niet altijd te kunnen herinneren, spullen als zijn sleutels soms kwijt te zijn, bij het leren van nieuwe dingen informatie minder goed op te kunnen slaan en afspraken altijd op te moeten schrijven. Het concentreren gaat redelijk, zo zegt hij. Wel meldt betrokkene sneller vermoeid te raken wanneer hij de aandacht lang vol dient te houden. Hij dwaalt op deze momenten wat sneller af. Verjaardagen zijn om deze reden te druk. Betrokkene heeft weinig last van hoofdpijn. Wel bemerkt hij soms een licht gevoel in het hoofd en heeft hij zo nu en dan aan de linkerkant van het hoofd een slapend en koud gevoel. Soms is betrokkene misselijk. Beloop van de klachten: De lichamelijke klachten zijn ontstaan sinds een ongeluk in 2010 waarbij betrokkene acuut werd blootgesteld aan TDI. De cognitieve klachten vallen het laatste jaar tot anderhalf jaar meer op. Zoekvraag: kan acute blootstelling aan TDI (tolueen di-isocyanaat) leiden tot achteruitgang van het cognitief functioneren? (En zo ja: op welk gebied?)
Page 11: Sources of medical knowledge (1 october 2012)

Catalogs

Bibliographic databases

Catalogs & digital library

!

Page 12: Sources of medical knowledge (1 october 2012)

Bibliographic databases

Pubmed ≠

Medline:In addition to MEDLINE citations, PubMed also contains:• In-process citations which provide a record for an article before it is indexed with MeSH and added to MEDLINE or converted to out-of-scope status.• Citations that precede the date that a journal was selected for

MEDLINE indexing (when supplied electronically by the publisher).• Some

OLDMEDLINE

citations that have not yet been updated with current vocabulary

and converted to MEDLINE status.•

Citations to articles that are out-of-scope (e.g., covering plate tectonics or astrophysics) from certain MEDLINE journals, primarily general science and general chemistry journals, for which the life sciences articles are indexed with MeSH for MEDLINE.• Citations to some additional life science journals that submit full text to PubMedCentral®

and receive a qualitative review by NLM.• Citations to

author manuscripts

of articles published by NIH-funded researchers.• Citations for a subset of books available on the

NCBI Bookshelf

(a citation for both the book and each chapter or section of the

book).

Source: http://www.nlm.nih.gov/pubs/factsheets/dif_med_pub.html

, last consulted 1 October 2012

Why search beyond Pubmed?# journals AND med AND psy AND emb unique

Medline 5,521 2,926

Psychinfo 596 2,208 1,402

Embase 2,360 571 3,982 1,412

Source http://www.ub.unimaas.nl/ub-fdgw/ubtest/co/m-p-e-coverage-overlap.htm, revised 11 March 2009

Page 13: Sources of medical knowledge (1 october 2012)

Guidelines & other resources of evidence

Page 14: Sources of medical knowledge (1 october 2012)

Questions?