sanguine sales deck_2015_jg_updated
TRANSCRIPT
Sanguine is bridging the gap
between patients and pharmas in the clinical R&D process by developing a novel @home clinical trial
platform that increases efficiency, transparency and big data collection.
Our platform leverages advancements in the shared economy and mobile / digital health
to deliver medical staff at the bedside in > 20 cities the US and serve 25 of the global pharmas.
INTRODUCTION TO SANGUINE
ResearchKit
ABOUT SANGUINE
Established in 2010 to serve the global clinical research market
> 300 pharmaceutical studies completed; > 5,000 study volunteer inquiries;> 2,000 applications for medical staff
Partnered with Mayo for biospecimen processing and testing, and invested in seed round
Experience working with the 20 largest pharmaceutical & biotechnology companies worldwide
our achievements
TRANSFORMATION OF CLINICAL RESEARCHvertical to horizontal industry shift
THE OLD VERTICAL CLINICAL RESEARCH INDUSTRY THE NEW HORIZONTAL CLINICAL RESEARCH INDUSTRY
OPEN APIs
SMARTPHONES/ WEARABLES
CLOSED SYSTEMS
AT-HOME TESTING ACADEMIC CLOSED
PRIVATE
SHARED ECONOMY
MEDICAL OFFICES / HOSPITALS
PATIENTSELF REPORT
MEDICAL RECORDS
NONPROFITS / PATIENT ADVOCACY
SOCIAL MEDIA MDs
TECHNOLOGY
LAB SERVICES
OPERATIONS
DATA REQUIREMENT
PATIENT RECRUITMENT
TECHNOLOGY
LAB SERVICES
OPERATIONS
DATA REQUIREMENT
PATIENT RECRUITMENT
QUINTILESPAREXEL
PPDICON
TRANSFORMATION OF CLINICAL RESEARCHcompanies by category
AT-HOME TESTING
TECHNOLOGY
LAB SERVICES
OPERATIONS
DATA REQUIREMENT
PATIENT RECRUITMENT
SANGUINE BUSINESS MODELproviding clinical research services
PROJECT DESIGNCONSULTATION
PATIENTRECRUITMENT
KIT PRODUCTION
MOBILE STAFFDEPLOYMENT
@HOME BIOSPECIMENCOLLECTION
PATIENTMONITORING
SEQUENCING,TESTING
PHARMAREQUESTS PROJECT
START Researchers request specific studies from Sanguine
Sanguine recruits patients for the study via social web and NPO partnerships
Sanguine's platform alerts Nurses on system to schedule blood draws at patient’s home
Mayo Clinic Bioservices performs testing, DNA sequencing, and other services using blood from the Nurses
AUTOMATED PLATFORM & ECOSYSTEM collecting biological and clinical data faster than ever before
PATIENT
PHARMA
MEDICAL STAFF
Sanguine has developed a disruptive, scalable platform serving the clinical research market through @home health services
Platform enables seamless communication and operations between pharma, patients, and medical staff
Significantly reduces time and cost for researchers to collect biological data
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FASTER COLLECTIONStudy enrollment through self-scheduler results in
faster collection.
TIME POINT STUDIESSafety, tolerability, or PK/PD
studies could benefit from more time points.
LONGITUDINAL DRAWSPost study surveillance or
longitudinal draws could be easily administered using at-
home service.
VALUE PROPOSITIONfaster collection, time point studies, longitudinal draws
TECHNOLOGY SOLUTIONS
RESEARCHER PORTAL MOBILE PHLEBOTOMY APPPATIENT PORTALSORP SangrePatient Portal
increasing effectiveness and efficiency
• Custom questionnaires
• Patient reported outcomes
• Rating Scales
• Co-Morbidities
• Treatment Efficacy
• Adverse Events
• Medical Record Summaries
• Clinical Testing
PARTICIPANT DATAobtain essential study information
greater access through diverse recruiting methods
• Blogs• Social media• Patient forums• Support groups
• Donor referrals to friends & family• Online advertisements• Non-Profit partnerships
PATIENT PORTAL
STUDY DASHBOARDView the status of all studies &
receive automatic notifications by email.
VISIT SCHEDULE & SAMPLE INFORMATION
Choose visit dates & sample quantity. Access upcoming schedule & sample
information.
RESEARCHER PORTALstay informed and updated
MOBILE PHLEBOTOMY APPaccess to major metropolitan cities around the nation
SANGREPhlebotomists receives draw information via Sangre (same day delivery, patient information, etc.)
40+ Cities Across
America
CASE STUDIESfulfill needs with unique study designs
Multiple Time Point Biospecimen Collections
Event-Based Biomarker Monitoring
Disease Interception Studies
01
02
03
MULTIPLE TIMEPOINTS BIOSPECIMEN COLLECTION
COHORT SELECTION40 donors collected at 3 time points, exclusions based on
medication & disease activity
PARTNERSHIP LAUNCHWorking with a sickle cell non-profit
organization, over 100 potential participants were identified in just 4
weeks
COMPLETIONAll 120 draws finished in 10 weeks!
STUDYLAUNCHED
STUDYCOMPLETED(10 WEEKS)
5 WEEKS
100 participantsrecruited
partnered with sickle cell non-profit
leveraging patient advocacy partners
SITE SUPPORTReduces site-work effort and
assist PI in performing monitoring and specimen
collection services
EVENT-BASED MONITORINGSanguine will implement patient monitoring tools to alert mobile staff when patients need to be
visited and specimens collected
AT-HOME PROCEDURESIncrease retention and study visit
compliance by going directly to patient's homes to conduct biweekly study
procedures
EVENT-BASED BIOMARKER MONITORINGremote site monitoring
PARTICIPANT RECRUITINGPatients can be selected based on
disease history, propensity for developing a disease or experiencing
certain symptoms
MONITORINGParticipants will be followed over
several months or years to observe how their disease progresses
COHORT SELECTION
DISEASE INTERCEPTION STUDY
LONGITUDINALASSESSMENT
TRIAL ENROLLMENT
RANDOMIZATIONSelected participants will be sent to the
clinical site for physician visit and enrollment into clinical trial
natural history study