rx for science literacy care and use of animals in research darrell e. hoskins, dvm, dipl. aclam...
TRANSCRIPT
Rx for Science Literacy Rx for Science Literacy Care and Use of Animals in ResearchCare and Use of Animals in Research
Darrell E. Hoskins, DVM, Dipl. ACLAMDarrell E. Hoskins, DVM, Dipl. ACLAM
Director, Animal Welfare TrainingDirector, Animal Welfare Training
Why Animals?Why Animals?
21st 21st century __________________________ ______________ ______________ demand medical advancements and safety. demand medical advancements and safety.
“societal expectations”
Why Animals?Why Animals?
-ethical issues -not instead of, but prior to research in humans-animals benefit too-no substitute yet-decreased scientific variables, increased consistency-life span and generation time
Use of Animals AnnuallyUse of Animals Annually
Use of animals by humans is a historical constant; “awareness” of animal use is the __________________.
“variable”
Animal Use in the USAnimal Use in the US
Number of Animals Used Annually (millions)
5000
150
22
Food
Pets
Research
Research Animals in the USResearch Animals in the US
19.8
1.6
0.22
0.11
0.11rats and mice
rabbits, guineapigs, hamsters,etc.
dog
cat
primates
-perspectives on -perspectives on numbers of animals numbers of animals used by humansused by humans
-species selections-species selections
-purpose-bred vs. -purpose-bred vs. random source random source animalsanimals
Use of Animals AnnuallyUse of Animals Annually
Professionals in Research Animal Professionals in Research Animal CareCare
Research animal care professionals have Research animal care professionals have chosen to assume society’s chosen to assume society’s _______________ for protecting the wellbeing of research for protecting the wellbeing of research animals.animals.
“responsibility”
-American College of Laboratory Animal Medicine-American Association for Laboratory Animal Science-Corporate Initiatives (animal welfare and quality science go hand-in-hand)
Professionals in Research Animal Professionals in Research Animal CareCare
AALAS Professional AALAS Professional JournalsJournals
Oversight of Research Animal Oversight of Research Animal WelfareWelfare
The “3 R’s”, ___________________, ___________________, and ______________ serve as the central guiding principal for all professional and regulatory oversight activities in biomedical research.
“reduction, refinement, replacement”
Oversight of Research Animal Oversight of Research Animal WelfareWelfare
- USDA Animal Welfare Act- AAALAC-OLAW/PHS Policy-FDA, EPA, OSHA, CPSC, etc.-government scientific review panels
Institutional Animal Care and Use Institutional Animal Care and Use Committees (IACUCs)Committees (IACUCs)
The IACUC is a federally mandated entity that assures the _____________ of research animals and represents the interests of the ______________.
welfare public
-membership -protocol review -inspections/reviews-investigate concerns
Institutional Animal Care and Use Institutional Animal Care and Use Committees (IACUCs)Committees (IACUCs)
