RESTORING THE JOY OF

CHILDLESS COUPLES

Epidemiology

An increasing % of married couple suffer from childlessness due to infertility

10% of these childless couple are due to unexplained infertility

A large % of these unexplained infertility can be traced to ovulation problems

Possible Intervention includes;

Timed Intercourse

-involves determination of ovulation

-objective to have intercourse within

12hrs of ovulation

OVULATIONcan be adversely affected by Abnormalities of the thyroid gland Over production of prolactin(a hormone

that leads to breast milk production) Excessive male hormone (androgen) STRESS-physical, psychological and

extreme life style changes Thereby making it extremely difficult to

determine ovulation

Present method of determination of OVULATION includes;

Basal Body Temp. Chart– Temp. Spike occurs after ovulation

Mid cycle pain- Sharp pain in the pelvic area usually

lasting some minutes or up to some hours

Cervical Mucus Changes– Should be Clear and Stretchy

Drawbacks of present techniques for determination of OVULATION Cumbersome nature of the

procedure Inaccurate results Process not easily

observed in most women Difficulty in interpretation

of result Messy procedure Expensive

Creating a need for the birth of a novel product;

Simple and convenient to use

Guarantees accurate results

Hygienic procedure enhancing compliance

Can easily and accurately predict ovulation period in women

Very affordable

Predicte

Mechanism of Action of

Detects Spike in Leutenizing Hormone in the urine in the middle of the Menstrual Cycle.

The Menstrual Cycle

Start cycle Day 1-5. FSH (from brain) released into bloodstream - initiate follicles in ovary to grow.

Follicles growDay 6 - 11. One follicle grow faster than the others. Follicles start producing Oestrogen hormone.

Oestrogen + FSH will prepare the womb (thicken) for later egg implantation.

LH released

OvulationFor 3 days, egg will travel in fallopian tube, waiting to be fertilized by a sperm.

24 - 36 hours later, egg released from Ovary. LH & FSH drop drastically.

Day 12 - 14. Lutenising Hormone (LH) released for egg to “ripen” and burst from ovary.

Continue….

The Menstrual Cycle……….continue

Ovulation Unfertilized

Egg expelled along with womb lining on the 28th day (menstruation)

Fertilized

Few days to travel to womb. Get implanted

Human Chorines Gonadotrophin (hCG) released for maintenance of the womb linings. Peak 60 - 80 days after conception.

Pregnancy Test + Positive !

The Ovulation Cycle

24-36 hours after LH surge

Oestrogen

FSH

Start test ?

Sample urine ?

WHEN TO…

START TESTING ON…

Length of Normal Cycle(Total days)

Start testing this many days after your last

period began.

Length of Normal Cycle (Total days)

Start testing this many days after your last

period began.

21 5 31 14

22 5 32 15

23 6 33 16

24 7 34 17

25 8 35 18

26 9 36 19

27 10 37 20

28 11 38 21

29 12 39 22

30 13 40 23

-A Non Invasive Procedure Collect urine once a day at about the same time

every day.

For best result reduce liquid intake for 2 hours before collecting urine and do not urinate for about 4 hours

Easy to use

Remove the Test Strip from the sealed pouch

Immerse the strip into the urine with the arrow end pointing towards the urine.

Do not immerse past the MAX (marker line)

TEST PROCEDURE

Cont… Take the strip out after 5 seconds and lay on a clean,

dry, non-absorbent surface. Wait for colored bands to appear. Depending on

concentration of LH in the test specimen, positive may be observed in as little as 40 seconds. However, to confirm negative results, the complete reaction time of 10 minutes is required.

DO NOT READ RESULT AFTER MORE THAN 30 MINUTES!

Ease in interpretation of result

INVALID NO LH SURGE i.e.

Negative LH SURGE i.e.

POSITIVE

Positive RESULT means…

OVULATION WILL OCCUR IN THE NEXT 24-36 HRS!!!

So you know when to advice intercourse to achieve the desired goal!– Conception– Meeting for Couples Apart

AND…

Aids determination of baby’s sex MALE - X or Y

CHROMOSONES FEMALE – X

CHROMOSONES ONLY

RECALL THAT….

X+Y Fusion = Male – X+X Fusion =Female

– Y-sperm cells are light and swim faster across the cervix

– X-sperm cells are heavy and swim slowly

– Y-sperm cells die faster

– X-sperm cells survive longer

SO..

Intercourse some days before Ovulation-– More likely to yield X+X fusion i.e. Female

Intercourse immediately after Ovulation– higher probability of Y+X fusion i.e. Male

Summary of benefits EASY AND CONVENIENT TO USE NON INVASIVE AND HYGIENIC

TECHNIQUE - ENHANCING COMPLIANCE ACCURATE RESULT SIMPLE TO INTERPRETE VERY AFFORDABLE AIDS NATURAL CONCEPTION ALSO USEFUL IN NATURAL SEX

SELECTION

With

You know with certainty when Ovulation will occur

You therefore also know when to advice intercourse– To Achieve conception and Sex Selection!

PRESCRIBE For Your Patients

You may just be God's hand waiting to touch some couples to restore JOY!

... a one–step test to determine the most fertile day to conceive!

THANK YOU!