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Page 1: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

References

Page 2: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

345 References

Abdulnabi AA, Emhemed AH, Hussein GD, Biacs PA. 1997. Determination of

antioxidant vitamins in tomatoes. Food Chem 60: 207-212.

Abell CW, Kwan SW. 2001. Molecular characterization of monoamineoxidases A and

B. Prog Nucleic Acid Res Mol Biology 65: 129-156.

Abramov AY, Canevari L, Duchen MR. 2004b. Calcium signals induced by amyloid

beta peptide and theirconsequences in neurons and astrocytes in culture.

Biochim Biophys Acta 6: 81-87

Adams M, Gmunder F, Hamburger M. 2007. Plants traditionally used in age related

brain disorders. A survey of ethnobotanical literature J Ethnopharmacol 113:

363-381.

Adesegun SA, Fajana A, Orabueze CI, Coker HAB. 2009. Evaluation of Antioxidant

Properties of Phaulopsis fascisepala C.B.Cl.Acanthaceae). Evid Based

Complement Alternat Med 6(2): 227-231.

Aebi HE. 1984. Catalase in vitro. Methods Enzymol 105: 121-122.

Afzal M, Al-Hadidi D, Menon M, Pesek J, Dhami MS. 2001. Ginger: an ethnomedical,

chemical and pharmacological review. Drug Metabol Drug Interac 18: 159-190.

Ahn EK, Jeon HJ, Lim EJ, Jung HJ, Park EH. 2007. Anti-inflammatory and anti-

angiogenic activities of Gastrodia elata. J Ethnopharmacol 110: 476-482.

Ahn J, Um M, Choi W, Kim S, Ha T. 2006. Protective effects of Glycyrrhiza uralensis

Fisch. on the cognitive deficits caused by β-amyloid peptide 25-35 in young

mice. Biogerontology 7(4): 239-247

Aisen PS. 2002. The potential of anti-inflammatory drugs for the treatment of

Alzheimer's disease. Lancet Neurol 1(5): 279-284.

Ajithkumar TT, Thangaradjou T, Kannan L. 2008. Spectral reflectance properties of

mangrove species of the Muthupettai mangrove environment, Tamil Nadu. J

Environ Biol 29(5): 785-788.

Aksenov MV, Aksenov MY, Payne RM, Trojanowski JQ, Schmidt KL, Carney JM,

Butterfield DA, Markesbery WR. 1999. Oxidation of cytosolic proteins and

expression of creatine kinase BB in frontal lobe in different neurodegenerative

disorders. Dement Geriatr Cogn Disord 10: 158-165.

Aksenov MY, Aksenova MV, Butterfield DA, Geddes JW, Markesbery WR. 2001.

Protein oxidation in the brain in Alzheimer‘s disease. Neuroscience 103: 373-

383.

Aksenov MY, Markesbery WR. 2001. Changes in thiol content and expression of

glutathione redox system genes in the hippocampus and cerebellum in

Alzheimer's disease. Neurosci Lett 302(2-3): 141-145.

Page 3: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

346 References

Alcaraz MJ, Ferrandiz ML. 1987. Modification of arachidonic metabolism by

flavonoids. J Ethnopharmacol 21: 209-229.

Al-Jumaily EF, Al-Amiry MHA, Assad JI. 2012. Hepatotoxic Activity of Essential Oil

from Nutmeg (Myristica Fragrans) Against Tetrachloride-Induced Hepatic

Damage In Mice. IOSRJPBS. 2(6): 1-8, ISSN: 2278-3008.

Alkam T, Nitta A, Mizoguchi H, Itoh A, Nabeshima T. 2007. A natural scavenger of

peroxynitrites, rosmarinic acid, protects against impairment of memory induced

by Abeta (25-35). Behav Brain Res 180: 139-145.

Allinson TMJ, Parkin ET, Turner AJ, Hooper NM. 2003. ADAMs family members as

amyloid precursor protein α-secretases. J Neurosci Res 74(3): 342-352.

Alongi DM. 2002. Present state and future of the world's mangrove forests. Environ

Conserv 293: 331-349.

Alvarez A, Alarcon A, Opazo C, Campos EO, Munoz F, Calderon FH, et al. 1998.

Stable complexes involving acetylcholinesterase and amyloid-β-fibrils change

the biochemical properties of the enzyme and increase the neurotoxicity of

Alzheimer's fibrils. J Neurosci 18: 407-416.

Alzheimer A. 1907. Über einen eigenartigen schweren Erkrankungsprozeß der

Hirnrinde. Neurologisches Centralblatt 23: 1129-1136.

Alzheimer‘s & Related Disorders Society of India- ADRSI. 2010. The Dementia India

Report: prevalence, impact, costs and services for Dementia. Shaji KS,

Jotheeswaran AT, Girish N, Bharath S, Dias A, Pattabiraman M, Varghese M

(eds.), ARDSI: New Delhi, ISBN: 978-81-920341-0-2.

Alzheimer‘s Association. 2012. Alzheimer‘s Disease Facts and Figures. Alzheimer’s &

Dementia, 8(2): 61 pp.

Alzheimer‘s disease International. 2010. World Alzheimer Report -The Global

economic impact of Dementia. Alzheimer‘s disease International: London.

American Association of Cereal Chemists (AACC). 2000. Approved Methods of the

AACC, 10th Ed. Methods 30-25, 44-15A, 46-30. The Association: St. Paul,

MN.

Amresh G, Singh PN, Rao CV. 2008. Toxicological screening of traditional medicine

Laghupatha (Cissampelos pareira) in experimental animals. J Ethnopharmacol

116: 454-460.

Anand P, Singh B. 2012. Synthesis and evaluation of novel 4-[(3H,3aH,6aH)-3-

phenyl)-4,6-dioxo-2-phenyldihydro-2H-pyrrolo[3,4-d]isoxazol-

5(3H,6H,6aH)yl] benzoic acid derivatives as potent acetylcholinesterase

inhibitors and anti-amnestic agents. Bioorg Med Chem 20: 521-530.

Page 4: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

347 References

Antia BS, Akpan EJ, Okon PA, Umoren IU. 2006. Nutritive and Anti nutritive

evaluation of Sweet Potatoes (Ipomoea batatas) leaves. Pak J Nutr 5: 166-168.

Anantharaman M, Tangpong J, Keller JN, Murphy MP, Markesbery WR, Kiningham

KK, St Clair DK. 2006. Beta-amyloid mediated nitration of manganese

superoxide dismutase: implication for oxidative stress in a APPNLH/NLH X

PS-1P264L/P264L double knock-in mouse model of Alzheimer‘s disease. Am J

Pathol 168: 1608-1618.

AOAC 2005. Official Methods of Analysis of AOAC International. (18th ed.), Official

Analysts Chemists: Gaithersburg, Maryland, USA.

Aragon G, Younossi ZM. 2010. ―When and how to evaluate mildly elevated liver

enzymes in apparently healthy patient‖. CCJM 77(3): 195-204.

Armstrong RA. 2011. The Pathogenesis of Alzheimer ‘s disease: A Reevaluation of the

―Amyloid Cascade Hypothesis‖. Int J Alzheimers Dis Article ID 630865, 6 pp.

doi:10.4061/2011/630865.

Asai M, Hattori C, Iwata N, Saido TC, Sasagawa N, Szabó B, Hashimoto Y, Maruyama

K, Tanuma S, Kiso Y, Ishiura S. 2006. The novel β-secretase inhibitor KMI-429

reduces amyloid β peptide production in amyloid precursor protein transgenic

and wild-type mice. J Neurochem 96(2): 533-540.

Asai M, Iwata N, Yoshikawa A, Aizaki Y, Ishiura S, Saido TC, Maruyama K. 2007.

Berberine alters the processing of Alzheimer's amyloid precursor protein to

decrease Abeta secretion. Biochem Biophys Res Commun 352(2): 498-502.

Ashafa AOT, Olunu OO. 2011. Toxicological evaluation of ethanolic root extract of

Morinda lucida (L.) Benth. (Rubiaceae) in male Wistar rats. J Nat Pharmaceut

2(2): 108-114.

Ashley J, Packard M, Ataman B, Budnik V. 2005. Fasciclin II signals new synapse

formation through amyloid precursor protein and the scaffolding protein

dX11/Mint. J Neurosci 25: 5943-5955.

Atack JR, Perry EK, Bonham JR, Perry RH, Tomlinson BE, Blessed G, Kawaguchi Y,

Honda H, Taniguchi-Morimura J, Iwasaki S. 1983. Molecular forms of

acetylcholinesterase in senile dementia of Alzheimer Type: Selective loss of the

intermediate (10S) Form. Neurosci Lett 40: 199-204.

Atta-ur-Rahman, Khalid A, Sultana N, Ghayur MN, Mesaik MA, Khan MR, Gilani AH,

Choudhary MI. 2006. New natural cholinesterase inhibiting and calcium

channel blocking quinoline alkaloids. J Enzyme Inhib Med Chem 21: 703 -710.

Page 5: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

348 References

Atti AR, Palmer K, Volpato S, Winblad B, De Ronchi D, Fratiglioni L. 2008. Late-life

body mass index and dementia incidence: Nine-year follow-up data from the

Kungsholmen Project. J Am Geriatr Soc 56: 111-116.

Augustinack JC, Schneider A, Mandelkow EM, Hyman BT. 2002. Specific tau-

phosphorylation sites correlate with severity of neuronal cytopathology in

Alzheimer‘s disease. Acta Neuropathol 103: 26-35.

Bachurin S, Bukatina E, Lermontova N, Tkachenko S, Afanasiev A, Grigoriev V,

Grigorieva I, Ivanov Y, Sablin S, Zefirov N. 2001. Antihistamine agent

Dimebon as a novel neuroprotector and a cognition enhancer. Ann NY Acad Sci

939: 425-435.

Baghurst PA, Baghurst KI, Record SJ. 1996. Dietary fiber, non-starch polysaccharides

and resistant starch a review. Food Aust 48: S3-S35.

Bagi Z, Cseko C, Toth E, Koller A. 2003. Oxidative stress-induced dysregulation of

arteriosal wall shear stress and blood pressure in hyperhomocysteinemia is

prevented by chronic vitamin C treatment. Am J Physiol Heart Circ Physiol

285: H2277-H2283.

Ballard CG, Perry EK. 2003. Butyrylcholinesterase: Potential Importance for the

Symptoms and Progression of Cognitive Decline in People with Dementia. Acta

Neurol Taiwan 12:109-113.

Bandaranayake WM. 2002. Bioactivities, Bioactive Compounds and Chemical

Constituents of Mangrove Plants. Wetlands Ecol Manag 10: 421-452

Bandyopadhyay S, Goldstein LE, Lahiri DK, Rogers JT. 2007. Role of the APP non-

amyloidogenic signaling pathway and targeting alpha-secretase as an alternative

drug target for treatment of Alzheimer‘s disease. Curr Med Chem 14: 2848-

2864.

Barber VS, Griffiths HR. 2003. Is glutathione an important neuroprotective effector

molecule against beta amyloid toxicity? Biofactors 17(1-4): 215-228.

Barik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye S, Satpati AK,

Zhang HY, Priyadarsini KI. 2007. Comparative study of copper (II)-curcumin

complexes as superoxide dismutase mimics and free radical scavengers. Eur J

Med Chem 42(4): 431-439.

Barnham KJ, Masters CL, Bush AI. 2004. Neurodegenerative diseases and oxidative

stress. Nat Rev Drug Discov 3(3): 205-214

Barten DM, Albright CF. 2008. Therapeutic Strategies for Alzheimer‘s Disease. Mol

Neurobiol 37(2-3): 171-186.

Page 6: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

349 References

Bastianetto S, ZhengWH, Qurion R. 2000b. The Ginkgo biloba extract (EGb 761)

protects and rescues hippocampal cells against nitric oxide induced toxicity:

involvement of its flavonoid constituents and protein kinase C. J Neurochem 74:

2268-2277.

Bates CJ, Bailey AJ, Prynne CJ, Levene CI. 1972. The effect of ascorbic acid on the

synthesis of collagen precursor secreted by 3T6 mouse fibroblasts in culture.

BBA 278: 372-390.

Beglopoulos V, Sun X, Saura CA, Lemere CA, Kim RD, Shen J. 2004. Reduced beta-

amyloid production and increased inflammatory responses in presenilin

conditional knock-out mice. J Biol Chem 279: 46907-46914.

Begum V, Sadique J. 1998. Long term effect of herbal drug Withania somnifera on

adjuvant induced arthritis in rats. Indian J Exp Biol 26: 877- 882.

Beher D, Clarke EE, Wrigley JD, Martin AC, Nadin A, Churcher I, Shearman MS.

2004. Selected non steroidal anti-inflammatory drugs and their derivatives target

gammasecretase at a novel site. Evidence for an allosteric mechanism. J Biol

Chem 279: 43419-43426.

Bellomo G, Mirabelli F, DiMonte D, Richelmi P, Thor H, Orrenius C, Orrenius S.

1987. Formation and reduction of glutathione-protein mixed disulfides during

oxidative stress: A study with isolated hepatocytes and menadione (2-methyl-

1,4-naphthoquinone). Biochem Pharmacol 36(8): 1313-1320.

Bennett BD, Denis P, Haniu M, Teplow DB, Kahn S, Louis JC, Citron M, Vassar R.

2000. A furin-like convertase mediates propeptide cleavage of BACE, the

Alzheimer‘s beta-secretase. J Biol Chem 275: 37712–37717

Benzie IFF, Strain JJ. 1996. Ferric reducing ability of plasma (FRAP) as a measure of

antioxidant power: The FRAP assay. Anal Biochem 239: 70-76.

Bergmans BA, De Strooper B. 2010. Gamma-secretases: from cell biology to

therapeutic strategies. Lancet Neurol 9(2): 215-226.

Bernauer U, Oberemm A, Madle S, Gundert-Remy U. 2005. The use of in vitro data in

risk assessment. Basic Clin Pharmacol Toxicol 96: 176-181.

Bertram L, Tanzi. RE. 2012. The genetics of Alzheimer‘s diseae. Prog Mol Biol Transl

Sci 107: 79-100.

Bertrand E, Brouillet E, Caille I, Bouillot C, Cole GM, Prochiantz A, Allinquant B.

2001. A short cytoplasmic domain of the amyloid precursor protein induces

apoptosis in vitro and in vivo. Mol Cell Neurosci 18: 503-511.

Page 7: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

350 References

Bhaskarachary K, Sankar Rao DS, Deosthale YG, Vinodini R. 1995. Carotene content

of some common and less familiar foods of plant origin. Food Chem 54: 189-

193.

Bingol F, Sener B. 1995. A review of terrestrial plants and marine organisms having

anti-inflammatory activity. Int J Pharm 33: 81-97.

Birkmayer JG. 1996. Coenzyme nicotinamide adenine dinucleotide: new therapeutic

approach for improving dementia of the Alzheimer type. Ann Clin Lab Sci 26:

1-9.

Blennow K, de Leon MJ, Zetterberg H. 2006. Alzheimer‘s disease. Lancet 368: 387-

403.

Boddapati S, Levites Y, Sierks MR. 2011. Inhibiting beta-secretase activity in

Alzheimer's disease cell models with single-chain antibodies specifically

targeting APP. J Mol Biol 405: 436-447.

Borroni B, Malinverno M, Gardoni F, Alberici A, Parnetti L, Premi E, Bonuccelli U,

Grassi M, Perani D, Calabresi P, Di Luca M, Padovani A. 2008. Tau forms in

CSF as a reliable biomarker for progressive supranuclear palsy. Neurol 71:

1796-1803.

Boyd-Kimball D, Poon HF, Lynn BC, Cai J, Pierce WM Jr, Klein JB, Ferguson J, Link

CD, Butterfield DA. 2006. Proteomic identification of proteins specifically

oxidized in Caenorhabditis elegans expressing human A(1-42): Implications

for Alzheimer‘s disease. Neurobiol Aging 27: 1239-1249.

Braak E, Braak H, Mandelkow EM. 1994. A sequence of cytoskeleton changes related

to the formation of neurofibrillary tangles and neuropil threads. Acta

Neuropathol 87: 554-567.

Braak H, Del Tredici K. 2011. The pathological process underlying Alzheimer‘s disease

in individuals under thirty. Acta Neuropathol 121: 171-181.

Breteler MM. 2000. Vascular risk factors for Alzheimer‘s disease: an epidemiologic

perspective. Neurobiol Aging 21(2): 153-160.

Briks J. 2006. Cholinesterase inhibitors for Alzheimer‘s disease. Cochrane Database

Syst Rev 25(1): CD005593.

Brookmeyer R, Johnson E, Ziegler-Graham K, Arrighi HM. 2007. Forecasting the

global burden of Alzheimer‘s disease. Alzheimers Dement 3(3): 186-191.

Brou C, Logeat F, Gupta N, Bessia C, LeBail O, Doedens JR, Cumano A, Roux R,

Black RA, Israël A. 2000. A Novel Proteolytic Cleavage Involved in Notch

Signaling: The Role of the Disintegrin-Metalloprotease TACE. Mol cell 5(2):

207-216.

Page 8: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

351 References

Brunhofer G, Fallarero A, Karlsson D, Batista-Gonzalez A, Shinde P, Gopi Mohan

C, Vuorela P. 2012. Exploration of natural compounds as sources of new

bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation:

The case of chelerythrine. Bioorg Med Chem 20(22): 6669-6679.

Buccafusco JJ, Letchworthc SR, Bencherifc M, Lippielloc PM. 2005. Long-lasting

cognitive improvement with nicotinic receptor agonists: mechanisms of

pharmacokinetic-pharmacodynamic discordance. Trends Pharmacol Sci 26(7):

352-360.

Budimir A. 2011. Metal ions, Alzheimer‘s disease and chelation theray. Acta Pharm

61: 1-14.

Bullock R, Touchon J, Bergman H, Gambina G, He Y, Rapatz G, Nagel J, Lane R.

2005. Rivastigmine and donepezil treatment in moderate to moderately severe

Alzheimer‘s disease over a 2 year period. Curr Med Res Opin 21(8): 1317-1327.

Bunyapraphatsara N, Srisukh V, Jutiviboonsuk A, Sornlek P, Thongbai noi W, Chuakul

W, Fong HHS, Pezzuto JM, Kosmeder J. 2002. Vegetables from the Mangrove

Areas. Thai J Phytopharm 9(1): 1-12.

Butler D, Bendiske J, Michaelis ML, Karanian DA, Bahr BA. 2007. Microtubule

stabilizing agent prevents protein accumulation-induced loss of synaptic

markers. Eur J Pharmacol 562(1-2): 20-27.

Butler MS. 2004. The Role of Natural Product Chemistry in Drug Discovery. J Nat

Prod 67 (12): 2141-2153.

Butterfield AD. 2011. Oxidative Stress in Alzheimer Disease: Synergy between the

Butterfield and Markesbery Laboratories. Neuromoleuclar Med 13(1): 19-22.

Butterfield DA, Bush AI. 2004. Alzheimer‘s amyloid -peptide (1-42): involvement of

methionine residue 35 in the oxidative stress and neurotoxicity properties of this

peptide. Neurobiol Aging 25: 563-568.

Butterfield DA, Castegna A, Drake J, Scapagnini G, Calabrese V. 2002. Vitamin E and

neurodegenerative disorders associated withoxidative stress. Nutr Neurosci

5(4): 229-239.

Butterfield DA, Hardas SS, Lange ML. 2010. Oxidatively modified glyceraldehyde -3-

phosphate dehydrogenasae (GAPDH) and Alzheimer‘s disease: many pathways

to neurodegeneration. J Alzheimers Dis 20(2): 369-393.

Butterfield DA, Lauderback CM. 2002. Lipid peroxidation and protein oxidation in

Alzheimer‘s disease brain: potential causes and consequences involving amyloid

beta-peptide-associated free radical oxidative stress. Free Radic Biol Med 32:

1050-1060.

Page 9: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

352 References

Butterfield DA, Pocernich CB. 2003. The glutamatergic system and Alzheimer's

disease: therapeutic implications. CNS Drugs 17(9): 641-652.

Buttini M, Malish E, Barbour R, Grajeda H, Motter R, Johnson-Wood K, Khan K,

Seubert P, Freedman S, Schenk D, Games D. 2005. - amyloid immunotheraphy

prevents synaptic degeneration in mouse model of Alzheimer‘s disease. J

Neurosci 25(40): 9096-9101.

Caccamo A, Oddo S, Billings LM, Green KN, Martinez-Coria H, Fisher A, LaFerla

FM. 2006. M1 receptors play a central role in modulating AD-like pathology in

transgenic mice. Neuron 49: 671-682.

Cacciatore I, Baldassarre L, Fornasari E, Mollica A, Pinnen F. 2012. Recent advances

in the treatment of neurodegenerative diseases based on GSH delivery systems.

Oxid Med Cell Longev Article ID 240146, 12 pgs, doi:10.1155/2012/240146.

Cai H, Wang Y, McCarthy D, Wen H, Borchelt DR, Price DL, Wong PC. 2001.

BACE1 is the major -secretase for generation of A peptides by neurons.

Nature Neuroscience 4: 233 - 234.

Caille I, Allinquant B, Dupont E, Bouillot C, Langer A, Muller U, Prochiantz A. 2004.

Soluble form of amyloid precursor protein regulates proliferation of progenitors

in the adult subventricular zone. Development 131: 2173-2181.

Caprez A, Arrigoni E, Amado R, Neukom H. 1986. Influence of different types of

thermal treatment on the chemical composition and physical properties of wheat

bran. J Cereal Sci 4: 233-239.

Caspersen C, Wang N, Yao J, Sosunov A, Chen X, Lustbader JW, Xu HW, Stern D,

McKhann G, Yan SD. 2005. Mitochondrial Abeta: a potential focal point for

neuronal metabolic dysfunction in Alzheimer's disease. FASEB J 19: 2040-

2041.

Ceballos I, Agid F, Delacourte A, Defossez, A, Nicole A, Sinet PM. 1990. Parkinson's

disease and Alzheimer's disease: Neurodegenerative disorders due to brain

antioxidant system deficiencies? In: Advances in experimental biology and

medicine: Antioxidant in therapy and preventive medicine. Emerit I, Packer L,

Auclair C (eds.), New York: Plenum Press; 493-498.

Cerbai F, Giovannini MG, Melani C, Enz A, Pepeu G. 2007. N1phenethyl-

norcymserine, a selective butyrylcholinesterase inhibitor, increases

acetylcholine release in rat cerebral cortex: a comparison with donepezil and

rivastigmine. Eur J Pharmacol 572: 142-150.

Chalimoniuk M, Stolecka A, Cakała M, Hauptmann S, Schulz K, Lipka U, Leuner K,

Eckert A, Muller WE, Strosznajder JB. 2007. Amyloid beta enhances cytosolic

Page 10: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

353 References

phospholipase A(2) level and arachidonic acid release via nitric oxide in APP-

transfected PC12 cells. Acta Biochim Polon 54: 611-623.

Chan PH. 2001. Reactive oxygen radicals in signaling and damage in the ischemic

brain. J Cereb Blood Flow Metab 21(1): 2-14.

Chanda S, Kaneria M. 2011. Indian nutraceutical plant leaves as a potential source of

natural antimicrobial agents. In: Science against Microbial Pathogens:

Communicating Current Research and Technological Advances, Formatex

Research Center: Badajoz, Spain.

Chao J, Lu TC, Liao JW, Huang TH, Lee MS, Cheng HY, Ho LK, Kuo CL, Peng WH.

2009. Analgesic and anti-inflammatory activities of ethanol root extract of

Mahonia oiwakensis in mice. J Ethnopharmacol 125(2): 297-303.

Chartier-Harlin MC, Parfitt M, Legrain S, Perez-Tur J, Brousseau T, Evans A, Berr C,

Vidal O, Roques P, Gourlet V. 1994. Apolipoprotein E, epsilon 4 allele as a

major risk factor for sporadic early and late-onset forms of Alzheimer‘s disease:

analysis of the 19q13.2 chromosomal region. Hum Mol Genet 3: 569-74.

Chen H, McCaffery JM, Chan DC. 2007. Mitochondrial Fusion Protects against

Neurodegeneration in the Cerebellum. Cell 130(3): 548-562.

Chen JX, Yan SS. 2010. Role of Mitochondrial Amyloid-β in Alzheimer's Disease. J

Alzheimer Dis 20(2): 569-578.

Chen Q, Prior M, Dargusch R, Roberts A, Riek R, Eichmann C. 2011. A Novel

Neurotrophic Drug for Cognitive Enhancement and Alzheimer‘s Disease. PLoS

One 6(2): e27865.

Chiou S, Lai G, Tsai Y, Lee Y, Lina L, Lin G. 2005. Kinetics and Mechanisms of

Acetylcholinesterase and Butyrylcholinesterase Inhibition by Cardiovascular

Drugs and Benzodiazepines. J Chin Chem Soc 52: 843-848.

Chodosh J, Reuben DB, Albert MS, Seeman TE. 2002. Predicting cognitive impairment

in high-functioning community-dwelling older persons: MacArthur Studies of

Successful Aging. J Am Geriat Soc 50: 1051-60.

Choi CW, Choi YH, Cha MR, KimYS, Yon GH, Hong KS, ParkWK, KimYH, Ryu SY.

2011. In vitro BACE-1 inhibitory activity of resveratrol oligomers from the seed

extract of Paeonia lactiflora. Planta Med 77: 374–376.

Choi MS, Lee SH, Cho HS, Kim Y, Yun YP, Jung HY, Jung JK, Lee BC, Pyo HB,

Hong JT. 2007. Inhibitory effect of obovatol on nitric oxide production and

activation of NFkB/MAP kinases in lipopolysaccharide-treated RAW

264.7cells. Eur J Pharmacol 556: 181-189.

Page 11: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

354 References

Choi SH, Hur JM, Yang EJ, Jun M, Park HJ, Lee KB, Moon E, Song KS. 2008. β-

Secretase (BACE1) Inhibitors from Perilla frutescens var. acuta. Arch Pharm

Res 31(2): 183-87.

Chung YK, Heo HJ, Kim EK, Kim HK, Huh TL, Lim Y, Kim SK, Shin DH. 2001.

Inhibitory effect of ursolic acid purified from Origanum majorana L on the

acetylcholinesterase. Mol Cells 11: 137-43.

Churcher I. 2006. Tau therapeutic strategies for the treatment of Alzheimer's disease.

Curr Top Med Chem 6(6): 579-595.

Citron M. 2004. Strategies for disease modification in Alzheimer disease. Nat Rev

Neurosci 5: 677-685.

Clarkson C, Maharaj VJ, Crouch NR, Grace OM, Pillay P, Matsabisa MG,

Bhagwandhin N, Smith PJ, Folb PI. 2004. In vitro antiplasmodial activity of

medicinal plants native to or naturalized in South Africa. J Ethnopharmacol 92:

177-191.

Colciaghi F, Borroni B, Zimmermann M, Bellone C, Longhi A, Padovani A, Cattabeni

F, Christen Y, Di Luca M. 2004 . Amyloid precursor protein metabolism is

regulated toward alpha-secretase pathway by Ginkgo biloba extracts. Neurobiol

Dis 16(2): 454-460.

Cole SL, Vassar R. 2007. The Alzheimer's disease β-secretase enzyme, BACE1. Mol

Neurodegener 2: 22, doi:10.1186/1750-1326-2-22.

Comery TA, Martone RL, Aschmies S, Atchison KP, Diamantidis G, Gong X, Zhou H,

Kreft, Pangalos MN, Reines JS, Jacobsen JS, Marquis KL. 2005. Acute-

Secretase Inhibition Improves Contextual Fear Conditioning in the Tg2576

Mouse Model of Alzheimer‘s Disease. J Neurosci 25(39): 8898-8902.

Contestabile A. 2011. The history of the cholinergic hypothesis. Behav Brain Res

221(2): 334-340.

Cordain L. 1999. Cereal Grains: Humanity's Double-edged Sword. World Rev Nutr Diet

84: 19-73.

Cotman CW Berchtold NC. 2002. Exercise: A behavioral intervention to enhance brain

health and plasticity. Trends Neurosci 25: 295-301.

Counts SE, Mufson EJ. 2005. The role of nerve growth factor receptors in cholinergic

basal forebrain degeneration in prodromal Alzheimer disease. J Neuropathol

Exp Neurol 64(4): 263-272.

Crews L, Masliah E. 2010. Molecular mechanisms of neurodegeneration in Alzheimer‘s

disease. Hum Mol Genet 19: R12-R20.

Page 12: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

355 References

Crouch PJ, Barnham KJ. 2012. Therapeutic redistribution of metal ions to treat

Alzheimer‘s disease. Acc Chem Res 45(9): 1604-1611.

Crunkhorn S. 2011. Neurodegenerative disorders: Restoring the balance. Nat Rev Drug

Discov 10: 576.

Cruts A, Gijselinck I, van der Zee J, Engelborghs S, Wils H, Pirici D, Rademakers R,

Vandenberghe R, Dermaut B, Martin JJ, van Duijn C, Peeters K, Sciot R,

Santens P, Santens P, Pooter TD, Matteijssens M, Van den Broeck M, Cuijt I,

Vennekens KI, De Deyn PP, Singh SK and Van Broeckhoven C. 2006. Null

mutations in progranulin cause ubiquitin-positive frontotemporal dementia

linked to chromosome 17q21. Nature 442: 920-924.

Cui H, Kong Y, Zhang H. 2012. Oxidative stress, mitochondrial dysfunction, and aging.

J Signal Transduction Article ID 646354, 13 pgs, doi:10.1155/2012/ 646354.

Cummings JL, Back C. 1998. The cholinergic hypothesis of neuropsychiatric symptoms

in Alzheimer‘s disease. Am J Geriatr Psychiatry 6(2-l): S64-S78.

Cummings JL. 2004. Alzheimer‘s disease. N Engl J Med 351(1): 56-67.

Dai Q, Borenstein AR, Wu Y, Jackson JC, Larson EB. 2006. Fruit and Vegetable

Juices and Alzheimer‘s Disease: The Kame Project. Am J Med 119(9): 751-759.

Dalle-Donnea I, Rossi R, Giustarini D, Milzani A, Colombo R. Protein carbonyl

groups as biomarkers of oxidative stress. Clin Chim Acta 329: 23-38.

Daou C, Zhang H. 2012. Study on Functional Properties of Physically Modified Dietary

Fibres Derived from Defatted Rice Bran. J Agric Sci 4(9): 85-97, ISSN 1916-

9752.

Darvesh S, Cash M, Andrew Reid G, Martin E, Mitnitski A, Geula C. 2012.

Butyrylcholinesterase is Associated with β-Amyloid Plaques in the Transgenic

APPSWE/PSEN1dE9 Mouse Model of Alzheimer Disease. J Neuropathol Exp

Neurol 71(1): 2-14.

Das A, Shanker G, Nath C, Pal R, Singh S, Singh HK. 2002. A comparative study in

rodents of standardized extracts of Bacopa monniera and Ginkgo biloba

anticholinesterase and cognitive enhancing activities. Pharmacol Biochem

Behav 73: 893-900.

De Strooper B, Annaert W. 2000. Proteolytic processing and cell biological functions of

the amyloid precursor protein. J Cell Sci 113 (11): 1857-1870.

Decker M. 2007. Recent advances in the development of hybrid molecules/designed

multiple compounds with antiamnesic properties. Mini Rev Med Chem 7: 221-

229.

Page 13: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

356 References

Deane R, Sagare A, Zlokovic B. 2008. The Role of the Cell Surface LRP and Soluble

LRP in Blood-Brain Barrier Aβ Clearance in Alzheimer‘s Disease. Pharm Des

14(16): 1601-1605.

DeMattos RB, Cirrito JR, Parsadanian M, May PC, O'Dell MA, Taylor JW, Harmony

JA, Aronow BJ, Bales KR, Paul SM, Holtzman DM. 2004. ApoE and clusterin

cooperatively suppress Abeta levels and deposition: evidence that ApoE

regulates extracellular Abeta metabolism in vivo. Neuron 41: 193-202.

Dere S, Gunes T, Sivaci R.1998. Spectrophotometric determination of chlorophyll A, B

and total carotenoid contents of some algae species using different solvents.

Turk J Bot 22: 13-17.

Deshpande, Mina E, Glabe C, Busciglio J. 2006. Different Conformations of

AmyloidInduce Neurotoxicity by Distinct Mechanisms in Human Cortical

Neurons. J Neurosci 26(22): 6011-6018

Devi L, Prabhu BM, Galati DF, Avadhani NG, Hindupur K. 2006. Accumulation of

Amyloid Precursor Protein in the Mitochondrial Import Channels of Human

Alzheimer‘s Disease Brain Is Associated with Mitochondrial Dysfunction. J

Neurosci 26(35): 9057-9068.

Devore EE. 2010. Dietary antioxidants and long-term risk of dementia. Arch Neurol

67(7): 819-25.

Dickson DW. 2004. Apoptotic mechanisms in Alzheimer neurofibrillary degeneration:

cause or effect? J Clin Invest 114(1): 23-27.

Dingman SL. 2002. Water in soils: Infiltration and redistribution, physical hydrology.

(2nd

ed.), Prentice-Hall Inc.: Upper Saddle River, New Jersey; pp. 646.

Dinis TCP, Madeira VMC, Almeida LM. 1994. Action of phenolic derivates

(acetoaminophen, salycilate, and 5-aminosalycilate) as inhibitors of membrane

lipid peroxidation and as peroxyl radica scavengers. Arch Biochem Biophys 315:

161-169.

Dorato MA, Engelhardt JA. 2005. The no-observed-adverse-effect-level in drug safety

evaluations: use, issues, and definition(s). Regul Toxicol Pharmacol 42: 265-274

Dringen R, Hirrlinger J. 2003. Glutathione pathways in the brain. Biol Chem 384: 505-

516.

Duce JA, Bush AI. 2010. Biological metals and Alzheimer's disease: Implications for

therapeutics and diagnostics. Prog Neurobiol 92(1): 1-18.

Duke JA, Wain KK. 1981. Medicinal plants of the world. Computer index with more

than 85,000 entries. 3vols.

Page 14: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

357 References

Duke NC. 2006. Australia's mangroves. The authoritative guide to Australia's

mangrove

Duncan AJ, Heales SJ. 2005. Nitric oxide and neurological disorders. Mol Aspects Med

26: 67-96.

Durairajan SSK, Yuan Q, Xie L, Chan WS, Kum WF, Koo I, Liu C, Song Y, Huang

YD, Li WLKM. 2008. Salvianolic acid B inhibits Ab fibril formation and

disaggregates preformed fibrils and protects against Aβ-induced cytotoxicty.

Neurochem Int 52: 741-750.

Eckert A, Hauptmann S, Scherping I, Rhein V, Müller-Spahn F, Götz J, Müller WE.

2008. Soluble Beta-Amyloid Leads to Mitochondrial Defects in Amyloid

Precursor Protein and Tau Transgenic Mice. Neurodegenerative Dis 5:157-159.

Edenharder R, van Petersdorf I, Rauscher V. 1993. Antimutagenic effects of flavonoids,

chalcones and structurally related compounds on the activity of 2-amino-3-

methylimidazol(4,5-f)quinoline (IQ) and other heterocyclic amine mutagens

from cooked food. Mutat Res 287: 261-274.

Ellman GL, Courtney KD, Andres V Jr., Featherstone RM. 1961. A new and rapid

colorimetric determination of acetylcholinesterase activity. Biochem. Pharmacol

7: 88-95.

Elmore S. 2007. Apoptosis: A Review of Programmed Cell Death. Toxicol Pathol

35(4): 495-516, doi: 10.1080/01926230701320337.

Elward K, Gasque P. 2003. Eat me and don‘t eat me signals govern the innate immune

response and tissue repair in the CNS: emphasis on the critical role of the

complement system. Mol Immunol 40: 85-94.

Ertekin-Taner N, Ronald J, Feuk L, Prince J, Tucker M, Younkin L, Hella M, Jain S,

Hackett A, Scanlin L, Kelly J, Kihiko-Ehman M, Neltner M, Hersh L, Kindy M,

Markesbery W, Hutton M, de Andrade M, Petersen RC, Graff-Radford N, Estus

S, Brookes AJ, Younkin SG. 2005. Elevated amyloid b protein (Ab42) and late

onset Alzheimer‘s disease are associated with single nucleotide polymorphisms

in the urokinase-type plasminogen activator gene. Hum Mol Genet 14(3): 447-

460.

Eskici G, Axelsen PH. 2012. Copper and oxidative stress in the pathogenesis of

Alzheimer's disease. Biochem 51(32): 6289-6311.

Esposito E, Matteo VD, Benigno A, Pierucci M, Crescimanno G, Giovanni GD. 2007.

Non-steroidal anti-inflammatory drugs in Parkinson's disease. Experiment

Neurol 205(2): 295-312.

Page 15: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

358 References

Estrada LD, Soto C. 2007. Disrupting beta-amyloid aggregation for Alzheimer disease

treatment. Curr Top Med Chem 7: 115-126.

Evandri MG, Battinelli L, Daniele C, Mastrangelo S, Bolle P, Mazzanti G. 2005. The

antimutagenic activity of Lavandula angustifolia (lavender) essential oil in the

bacterial reverse mutation assay. Food Chem Toxicol 43: 1381-1387.

Falcioni ML, Nasuti C, Bergamini C, Fato R, Lenaz G, Gabbianelli R. 2010. The

primary role of glutathione against nuclear DNA damage of striatum induced by

permethrin in rats. Neuroscience 168(1): 2-10.

Fang F, Liu GT. 2006. Protective effects of compound FLZ on bamyloid peptide-(25-

35)-induced mouse hippocampal injuryand learning and memory impairment.

Acta Pharmacol Sin 27: 651-658.

Farris W, Mansourian S, Chang Y, Lindsley L, Eckman EA, Frosch MP, Eckman CB,

Tanzi RE, Selkoe DJ, Guenette S. 2003. Insulin-degrading enzyme regulates the

levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein

intracellular domain in vivo. Proc Natl Acad Sci USA 100: 4162-7.

Faux NG, Ritchie CW, Gunn A, Rembach A, Tsatsanis A, Bedo J. 2010. PBT2 rapidly

improves cognition in Alzheimer's disease: additional phase II analyses. J

Alzheimers Dis 20: 509-516.

Fein G, Di Sclafani V, Tanabe J, Cardenas V, Weiner MW, Jagust WJ, Reed BR,

Norman D, Schuff N, Kusdra L, Greenfield T andChui HD. 2000.

Hippocampal and cortical atrophy predict dementia in subcortical ischemic

vascular disease. 55: 1626-35.

Feng Y, Wang X. 2012. Antioxidant Therapies for Alzheimer‘s Disease. Oxid Med

Cell Longev - 2012, Article ID 472932, 17 pages, doi:10.1155/2012/472932

Feng Y, Yang SG, Du XT, Zhang X, Sun XX, Zhao M, Sun GY, Liu RT. 2009. Ellagic

acid promotes Abeta42 fibrillization and inhibits Abeta induced neurotoxicity.

Biochem Biophys Res Commun 390(4): 1250-1254.

Feng Z, Zhang J. 2004. Protective effect of melatonin on β-amyloid-induced apoptosis

in rat astroglioma c6 cells and its mechanism. Free Radical Biol Med 37(11):

1790-1801.

Ferreira A, Proença C, Serralheiro MLM, Araújo MEM. 2006. The in vitro screening

for acetylcholinesterase inhibition and antioxidant activity of medicinal plants

from Portugal. J Ethnopharmacol 108: 31-37.

Ferreira ICFS, Vargas VMF. 1999. Mutagenicity of medicinal plant extracts in

Salmonella/microsome assay. Phytother Res 13: 397-400.

Page 16: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

359 References

Ferreiro E, Baldeiras I, Ferreira IL, Costa RO, Rego AC, Pereira CF, Oliveira CR.

2012. Mitochondrial and endoplasmic reticulum associated oxidative stress in

Alzheimer's disease: from pathogenesis to biomarkers. Int J Cell Biol 735206,

doi: 10.1155/2012/735206.

Fiala JC, Feinberg M, Peters A, Barbas H. 2007. Mitochondrial degeneration in

dystrophic neurites of senile plaques may lead to extracellular deposition of fine

filaments. Brain Struct Funct 212: 195-207.

Fleury N, Lahaye M. 1991. Chemical and physico-chemical characterisation of fibers

from Laminaria digitata (Kombu Breton): A physiological approach. J Sci Food

Agric 55: 389-400.

Floyd RA, Hensley K. 2002. Oxidative stress in brain aging. Implications for

therapeutics of neurodegenerative diseases. Neurobiol Aging 23(5): 795-807.

Food and nutrition board (2002). Dietary, functional and total fiber. In: Institute of

medicine, dietary reference intakes for energy, carbohydrate, fiber, fat, fatty

acids, cholesterol, protein and amino acids (macronutrients). National academy

press: Washington DC, USA; 265-334

Forman MS, Trojanowski JQ, and Lee VM. 2004. Neurodegenerative diseases: a

decade of discoveries paves the way for therapeutic breakthroughs. Nat Med 10:

1055-1063.

Fox NC, Black RS, Gilman S, Rossor MN, Griffith SG, Jenkins L, Koller M, 2005.

Effects of Aβ immunization (AN1792) on MRI measures of cerebral volume in

Alzheimer disease. Neurology 64(9): 1563-1572.

Francis PT, Nordberg N, Arnold SE. 2005. A preclinical view of cholinesterase

inhibitors in neuroprotection: do they provide more than symptomatic benefits

in Alzheimer's disease. Trends Pharmcol Sci 26(2): 104-111.

Franz G, Beer R, Kampfl A, Engelhardt K, Schmutzhard E,Ulmer H, Deisenhammer F.

2003. Amyloid b 1 -42 and tau in cerebrospinal fluid after severe traumatic brain

injury. Neurology 60: 1457-1461.

Fratiglioni L, Qui C. 2009. Prevention of common neurodegenerative disorders in the

elderly. Exp Gerontol 44(1-2): 46-50.

Froissard P, Monrocq H, Duval D. 1997. Role of glutathione metabolism in the

glutamate-induced programmed cell death of neuronal-like PC12 cells. Eur J

Pharmacol 326(1): 93-99.

Fu A-L, Dong Z-H, Sun M-J. 2006. Protective effect of N-acetyl-l-cysteine on amyloid

β-peptide-induced learning and memory deficits in mice. Brain Res 1109(1):

201-206.

Page 17: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

360 References

Fujiwara H, Tabuchi M, Yamaguchi T, Iwasaki K, Furukawa K, Sekiguchi K, Ikarashi

Y, Kudo Y, Higuchi M, Saido TC, Maeda S, Takashima A, Hara M, Yaegashi

N, Kase Y , Arai H. 2009. A traditional medicinal herb Paeonia suffruticosa and

its active constituent 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose have

potent anti-aggregation effects on Alzheimer's amyloid beta proteins in vitro and

in vivo. J Neurochem 109(6): 1648-1657

FujiwaraH, Iwasaki K, Furukawa K, Seki T, He M, Maruyama M, Tomita N, Kudo Y,

Higuchi M, Saido TC, Maeda S, Takashima A, Hara M, Ohizumi Y, Ara H.

2006. Uncaria rhynchophylla, a Chinese medicinal herb, has potent

antiaggregation effects on Alzheimer's β-amyloid proteins. J Neurosci Res

84(2): 427-433.

Fukumoto H, Cheung BS, Hyman BT, Irizarry MC. 2002. β-Secretase protein and

activity are increased in the neocortex in Alzheimer disease. Arch Neurol

59:1381-1389.

Furukawa-Hibi Y, Alkam T, Nitta A, Matsuyama A, Mizoguchi H, Suzuki K,

Moussaoui S, Yu QS, Greig NH, Nagai T, Yamada K. 2011.

Butyrylcholinesterase inhibitors ameliorate cognitive dysfunction induced by

amyloid-β peptide in mice. Behav Brain Res 225(1): 222-229.

Galasko D, Montine TJ. 2010. Biomarkers of oxidative damage and inflammation in

Alzheimer‘s disease. Biomark Med 4(1): 27-36.

Gamba P, Testa G, Sottero B, Gargiulo S, Poli G, Leonarduzzi G. 2012. The link

between altered cholesterol metabolism and Alzhiemer‘s disease. Ann NY Acad

Sci 1259: 54-64.

Gandhi S, Abramov AY. 2012. Mechanism of Oxidative Stress in Neurodegeneration.

Oxid Med Cell Longev Article ID 428010, 11 pgs, doi:10.1155/2012/428010.

Garcia-Alloza M, Borrelli LA, Hyman BT, Bacskai BJ. 2010. Antioxidants have a rapid

and long-lasting effect on neuritic abnormalities in APP: PS1 mice. Neurobiol

Aging 31(12): 2058-2068.

Garwood CJ, Pooler AM, Atherton J, Hanger DP, Noble W, 2011. Astrocytes are

important mediators of Aβ-induced neurotoxicity and tau phosphorylation. Cell

Death Dis 2: e167, doi:10.1038/cddis.2011.50.

Genovese S, Foreman JE, Borland MG, Epifano F, Gonzalez FJ, Curini M, Peters JM.

2010. A natural propenoic acid derivative activates peroxisome proliferator-

activated receptor-β/δ(PPARβ/δ). Life Sci 86: 493-498.

Gertz HJ, Kiefer M. 2004. Review about Ginkgo biloba special extract EGB 761. Curr

Pharm Des 10(3): 261-264.

Page 18: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

361 References

Geschwind DH. 2003. Tau phosphorylation, tangles and neurodegeneration: the chicken

or the egg? Neuron 40(3): 457-60.

Ghafoorunissa J, Pangrekar J. 1993. Vegetables as sources of alpha-linolenic acid in

Indian diets. Food Chem 47(2): 121-124.

Ghimeray AK, Jin CE, Ghimire BK, Cho DH. 2009. Antioxidant activity and

quantitative estimation of azadirachtin and nimbin in Azadirachta Indica A. Juss

grown in foothills of Nepal. Afr J Biotechnol 8(13): 3084-3091.

Ghosh AK, Kumaragurubaran N, Hong L, Koelsh G, Tang J. 2008. Memapsin 2 (Beta-

Secretase) Inhibitors: Drug Development. Curr Alzheimer Res 5(2): 121-131.

Gilchrist AL, Cowan N, Naveh-Benjamin M. 2008. Working memory capacity for

spoken sentences decreases with adult ageing: recall of fewer but not smaller

chunks in older adults. Memory 16: 773-787.

Gilgun-Sherki Y, Melamed E, Offen D. 2003. Antioxidant treatment in Alzheimer

disease. J Mol Neurosci 21(1): 1-11.

Giulian D. 1987. Ameboid microglia as effectors of inflammation in the central nervous

system. J Neurosci Res 18(1):155-171.

Goate, A, Chartier-Harlin MC, Mullan M, Brown J, Crawford F, Fidani L, Giuffra L,

Haynes A, Irving N, James L. 1991. Segregation of a missense mutation in the

amyloid precursor protein gene with familial Alzheimer‘s disease. Nature 349:

704-706.

Golde TE, Schneider LS, Koo EH. 2011. Anti-Aβ Therapeutics in Alzheimer's Disease:

The Need for a Paradigm Shift. Neuron 69(2): 203-213.

Gómez-Ramos P, Morán MA. 1997. Ultrastructural localization of

butyrylcholinesterase in senile plaques in the brains of aged and Alzheimer

disease patients. Mol Chem Neuropathol 30(3): 161-173.

Gong CX, Iqbal K. 2008. Hyperphosphorlyation of microtubule associated protein tau:

a promising therapeutic target for Alzheimer disease. Curr Med Chem 15(23):

2321-2328.

Gong Y, Xue B, Jiao J, Jing L, Wang X. 2008. Triptolide inhibits COX-2 expression

and PGE2 release by suppressing the activity of NF-κB and JNK in LPS-treated

microglia. J Neurochem 107(3): 779-788.

Gopalan C, Sastri RBV, Balasubramaniam SC, Narasinga Rao BS, Deosthale YG, Pant

KC. 1996. Nutritive value of Indian foods. National Institute of Nutrition, Indian

Council for Medical Research, Hyderabad, India.

Page 19: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

362 References

Gozal E, Sachleben Jr LR, Rane MJ, Vega C, Gozal D. 2005. Mild sustained and

intermittent hypoxia induce apoptosis in PC12 cells via different mechanisms.

Am J Physiol Cell Physiol 288: C535e42.

Gozes I. 2007. Activity-dependent neuroprotective protein: from gene to drug

candidate. Pharmacol Ther 114: 146-154.

Granholm AC, Henry S, Hebert MA, Eken S, Gerhardt GA, Vanhorne C. 1998. Kidney

cografts enhance fiber outgrowth from ventral mesencephalic grafts to the 6-

OHDA-lesioned striatum, and improve behavioral recovery. Cell Transplant 7:

197-212.

Gray CW, Patel AJ. 1993. Regulation of β-amyloid precursor protein isoform mRNAs

by transforming growth factor-β1 and interleukin-1β in astrocytes. Mol Brain

Res 19(3): 251-256.

Greenlee W, Clader J, Asberom T, McCombie S, Ford J, Guzik H, Kozlowski J, Li S,

Liu C, Lowe D, Vice S, Zhao H, Zhou G, Billard W, Binch H, Crosby R, Duffy

R, Lachowicz J, Coffin V, Watkins R, Strader C, Taylor L, Cox K. 2001.

Muscarinic agonsits and antagonists in the treatment of Alzheimer‘s disease.

Farmco 56: 247-250.

Grossman M, Smith EE, Koenig PL, Glosser G, Rhee J, Dennis K. 2003.

Categorization of object descriptions in Alzheimer‘s disease and frontotemporal

dementia: Limitation in rule-based processing. Cogn Affect Behav Neurosci

3(2): 120-132.

Grutter M. 2000. Caspases: key players in programmed cell death. Curr Opin Struct

Biol 10: 649-655

Gülçin I, Oktay M, Kireçci E, Küfreviolu O. 2003. Screening of antioxidant and

antimicrobial activities of anise (Pimpinella anisum L.) seed extracts. Food

Chem 83: 371-382.

Guo JY, Xie HQ, Choi RCY. 2010. Galangin, a flavonol derived from Rhizoma

Alpiniae Officinarum, inhibits acetylcholinesterase activity in vitro. Chem Biol

Interact 187(1-3): 246-248.

Guo Q, Zhao B, Li M, Shen S, Xin W. 1996. Studies on protective mechanisms of four

components of green tea polyphenols against lipid peroxidation in

synaptosomes. Biochim Biophys Acta 1304(3): 210-222.

Gupta P, Premavalli KS. 2010. Effect of particle size reduction on physicochemical

properties of ashgourd (Benincasa hispida) and radish (Raphanus sativus) fibres.

Int J Food Sci Nutr 61(1):18-28.

Page 20: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

363 References

Gupta S, Lakshmi AJ, Manjunath MN, Prakasha J. 2005. Analysis of nutrient and

antinutrient content of underutilized green leafy vegetables. LWT Food Sci

Technol 38: 339-345.

Gupta VB, Rao KS. 2007. Anti-amyloidogenic activity of S-allyl-L-cysteine and its

activity to destabilize Alzheimer's beta-amyloid fibrils in vitro. Neurosci Lett

429(2-3): 75-80.

Gurib-Fakim A, Subratty H, Narod G, Govindern Soulange Mahomoodally F. 2005.

Biological activity from indigenous medicinal plant of Mauritius. Pure Appl

Chem 77(1): 41-51.

Haan MN, Wallace R. 2004. Can dementia be prevented? Brain aging in a population

based context. Annu Rev Public Health. 25:1-24.

Haapasalo A, Kovacs DM. 2011. The Many Substrates of Presenilin/γ-Secretase. J

Alzheimer Dis 25(1): 3-28.

Habig WH, Pabst MJ, Jakoby WB. 1974. Glutathione S-transferases. The first

enzymatic step in mercapturic acid formation. J Biol Chem 249(22):7130-7139.

Hagerman AE, Riedl KM, Jones GA, Sovik KN, Ritchard NT, Hartzfeld PW, Riechel

TL. 1998. High molecular weight plant polyphenolics (tannins) as biological

antioxidants. J Agric Food Chem 46: 1887-1892.

Hajiaghaee R, Akhondzadeh S. 2012. Herbal Medicine in the Treatment of Alzheimer‘s

Disease J Med Plants 11(41): 1-7.

Hakura A, Shimada H, Nakajima M, Sui H, Kitamoto S, Suzuki S, Satoh T. 2005.

Salmonella/human S9 mutagenicity test: a collaborative study with 58

compounds. Mutagenesis 20(3): 217—228.

Halligudi N. 2012. Pharmacological properties of flax seeds: A review. Hygeia.J D Med

4 (2): 70-77.

Halliwell B, Gutteridge JMC, Arnoma OL. 1987. The deoxyribose method: A simple

test tube assay for the determination of rate constant for reaction of hydroxyl

radical. Analytical Biochemistry 165: 215-219.

Hansen RA, Gartlehner G, Webb AP, Morgan LC, Moore CG, Jonas DE. 2008.

Efficacy and safety of donepezil, galantamine and rivastigmine for the treatment

of Alzheimer‘s disease: A systematic review and meta-analysis. Clin Interv

Aging 3(2): 211-225.

Harborne JB, Harborne AJ.1998. Phytochemical Methods: A Guide to Modern

Techniques of Plant Analysis. Kluwer Academic Publishers: London, UK.

Page 21: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

364 References

Harkness JE, Turner PV Woude SV, Wheler CL. 2010. Biology and Medicine of

Rabbits and Rodents. In: Clinical Procedures: Hematology, clinical chemistry

and urinalysis, 5th (ed.), John Wiley and Sons: USA; 116-130.

Hayashi Y, Shi SH, Esteban JA, Piccini A, Poncer JC, Malinow R. 2000. Driving

AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1

and PDZ domain interaction. Science 287: 2262-2267.

Heinrich M, Lee Teoh H. 2004. Galanthamine from snowdrop-the development of

modern drug against Alzheimer‘s disease from local Caucasian knowledge. J

Ethnopharmacol 92(2-3): 147-162.

Heneka MT, O'Banion MK. 2007. Inflammatory processes in Alzheimer's disease. J

Neuroimmunol 184(1-2): 69-91.

Heo SJ, Park PJ, Park EJ, Kim SK, Jeon YJ. 2005. Antioxidant Bioprospecting for

bioactives from seaweeds: potential, obstacles and alternatives activity of

enzymatic extracts from brown seaweed Ecklonia cava by electron spin

resonance spectrometry and comet assay. Eur Food Res Technol 221: 41-47.

Hillhouse BJ, Ming DS, French CJ, Neil TGH. 2004. Acetylcholinesterase inhibitors in

Rhodiola rosea. Pharm Biol 42: 68-72.

Hiramatsu M, Takiguchi O, Nishiyama A, Mori H. 2010. Cilostazol prevents amyloid β

peptide25-35-induced memory impairment and oxidative stress in mice. Br J

Pharmacol 161(8): 1899-1912.

Ho A, Sudhof TC. 2004. Binding of F-spondin to amyloid-beta precursor protein: a

candidate amyloid-beta precursor protein ligand that modulates amyloid-beta

precursor protein cleavage. Proc Natl Acad Sci USA 101(8): 2548-2553.

Hodges JR. 2006. Alzheimer‘s centennial legacy: origins, landmarks and the current

status of knowledge concerning cognitive aspects. Brain 129: 2811-2822.

Hoi CP, Ho YP, Baum L, Chow AHL.2010. Neuroprotective Effect of Honokiol and

Magnolol, Compounds from Magnolia offi cinalis, on Beta-amyloid-induced

Toxicity in PC12 Cells. Phytother Res 24(10):1538-1542.

Holenz J, Pauwels PJ, Díaz JL, Mercè R, Codony X, Buschmann H. 2006. Medicinal

chemistry strategies to 5-HT6 receptor ligands as potential cognitive enhancers

and antiobesity agents. Drug Discov Today 11(7-8): 283-299.

Hong Y, Chena C, Chang J, Wang S, Sy W, Chou C, Howng S. 2000. Cloning and

characterization of a novel human ninein protein that interacts with the glycogen

synthase kinase 3. Biochim Biophys Acta 1492: 513-516.

Page 22: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

365 References

Hong-Qi Y, Zhi-Kun S, Sheng-Di C. 2012. Current advances in the treatment of

Alzheimer‘s disease: focused on considerations targeting Aβ and tau. Transl

Neurodegener 1: 21.

Honson NS, Johnson RL, Huang W, Inglese J, Austin CP, Kuret J. 2007.

Differentiating Alzheimer disease-associated aggregates with small molecules.

Neurobiol Dis 28: 251-260.

Hooper NM, Turner AJ. 2002. The search for alpha secretase and its potential as a

therapeutic approach to Alziemer diseases. Curr Med Chem 9(11): 1107-1119.

Horn RC, Vargas VMF. 2003. Antimutagenic activity of extracts of natural substances

in the Salmonella/microsome assay. Mutagenesis 18(2): 113-118.

Howes MJ, Houghton PJ. 2012. Ethnobotanical treatment strategies against Alzheimer's

disease. Curr Alzheimer Res 9(1): 67-85.

Huang TC, Lu K-T, Wo Y-YP, Wu Y-J, Yang. 2011. Resveratrol Protects Rats from

Ab-induced Neurotoxicity by the Reduction of iNOS Expression and Lipid

Peroxidation. PLoS one 6(12): e29102.

Hudson SA, Ecroyd H, Dehle FC, Musgrave IF, Carver JA. 2009. (−)-Epigallocatechin-

3-Gallate (EGCG) Maintains κ-Casein in Its Pre-Fibrillar State without

Redirecting Its Aggregation Pathway. J Mol Biol 392(3): 689-700.

Hwang EM, Ryu YB, Kim HY, Kim DG, Hong SG, Lee JH, Curtis-Long MJ, Jeong

SH, Park JY, Park KH. 2008. BACE1 inhibitory effects of lavandulyl

flavanones from Sophora flavescens. Bioorg Medicinal Chem Lett 16: 6669-

6674.

Hye MA, Taher MA, Ali MY, Ali MU, Zaman S. 2009. Isolation of (+)-Catechin from

Acacia Catechu (Cutch Tree) by a Convenient Method. J Sci Res 1(2): 300-302.

Hynd MR, Scott HL, Dodd PR. 2004. Glutamate-mediated excitotoxicity and

neurodegeneration in Alzheimer‘s disease. Neurochem Int 45(5): 583-95.

Ianiski FR, Alves CB, Souza AC, Pinton S, Roman SS, Rhoden CR, Alves MP,

Luchese C. 2012. Protective effect of meloxicam-loaded nanocapsules against

amyloid-β peptide-induced damage in mice. Behav Brain Res 230(1): 100-107.

Ikeda K, Negishi H, Yamori Y. 2003. Antioxidant nutrients and hypoxia/ischemia brain

injury in rodents. Toxicol 189(1-2): 55-61.

Imdadul H, Wirakarnain S, Koshy P, Arash R, Shariff HABM, Ma TR. 2011. Valuable

Antioxidant and Antimicrobial Extracts from Rhizophora Mucronata of

AsiaticMangrove Forests Res J Biotechnol 6 (1): 10-14.

Page 23: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

366 References

Inanami O, Watanabe Y, Syuto B, Nakano M, Tsuji M, Kuwabara M. 1998. Oral

administration of (-)catechin protects against ischemia-reperfusion-induced

neuronal death in the gerbil. Free Radic Res 29(4): 359-365.

Inestrosa NC, Toledo EM. 2008. The role of Wnt signaling in neuronal dysfunction in

Alzheimer's Disease. Mol Neurodegener 3:9.

Ingkaninan K, Temkitthawon P, Chuenchom K, Yuyaem T, Thongnoi W. 2003.

Screening for acetylcholinesterase inhibitory activity in plants used in Thai

traditional rejuvenating and neurotonic remedies. J Ethnopharmacol 89: 261-

264.

Iqbal K, Liu F, Gong CX, Alonso AC, Iqbal IG. 2009. Mechanisms of tau-induced

neurodegeneration. Acta Neuropathologica 118(1): 53-69.

Irshad M, Zafarya M, Singh M, Rizvi MMA. 2012. Comparative Analysis of the

Antioxidant Activity of Cassia fistula Extracts. Int J Med Chem Article ID

157125, 6 pgs, doi:10.1155/2012/157125.

Jagetia GC, Rao SK, Baliga MS, Babu KS. 2004. The evaluation of nitric oxide

scavenging activity of certain herbal formulations in vitro: a preliminary study.

Phytother Res 18(7): 561-565.

James LE, Fogler KA, Tauber SK. 2008. Recognition memory measures yield

disproportionate effects of aging on learning face-name associations. Psychol

Aging 23: 657-664.

Jang JH, Surh YJ. 2005. AP-1 mediates -amyloid-induced iNOS expression in PC12

cells via the ERK2 and p38 MAPK signalin.g pathways. Biochem Biophys Res

Commun 331: 1421-1428.

Jankowsky JL, Slunt HH, Gonzales V, Savonenko AV, Wen JC, Jenkins NA, Copeland

NG, Younkins LH, Lester HA, Younkins SG, Borchelt DR. 2005. Persistent

Amyloidosis following Suppression of A Production in a Transgenic Model of

Alzheimer Disease. PLoS Med 2(12): 1318-1333.

Jarrett HW, Cooksy KD, Ellis B, Anderson JM. 1986. The separation of o-

phthalaldehyde derivatives of amino acids by reversed-phase chromatography

on octylsilica column. Anal Biochem 153: 189-198.

Jayanthi P, Lalitha P. Reducing power of the Solvent extracts of Eichhorniacrassipes

(Mart.) SOLns. Int J Pharm Pharm Sci 3(3): 126­128.

Jeon SY, Bae KH, Seong YH, Song KS. 2003. Green tea catechins as a BACE 1

(betasecretase) inhibitor. Bioorg Med Chem Lett 13: 3905-3908.

Page 24: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

367 References

Jeon SY, Kwon SH, Seong SY, Bae K, Hura JM, Lee YY, Suhd DY, Song KS. 2007. β-

secretase (BACE1)-inhibiting stilbenoids from Smilax Rhizoma. Phytomedicine

14: 403-408.

Jesudason EP, Masilamoni JG, Ashok BS, Baben B, Arul V, Jesudoss KS, Jebaraj

WCE, Dhandayuthapani S, Vignesh S, Jayakumar R. 2008. Inhibitory effects of

short-term administration of dl-α-lipoic acid on oxidative vulnerability induced

by Aβ amyloid fibrils (25-35) in mice. Mol Cell Biochem 311(1-2): 145-156.

Jhoo JH, Kim HC, Nabeshima T, Yamada K, Shin EJ, Jhoo WK, Kim W, Kang KS, Jo

SA, Woo JI. 2004. Beta-amyloid (1-42)-induced learning and memory deficits

in mice: involvement of oxidative burdens in the hippocampus and cerebral

cortex. Behav Brain Res 155(2):185-196.

Jia H, Jiang Y, Ruan Y, Zhang Y, Ma X, Zhang J, Beyreuther K, Tu P, Zhang D. 2004.

Tenuigenin treatment decreases secretion of the Alzheimer's disease amyloid

beta-protein in cultured cells. Neurosci Lett 367: 123-128.

Jick H, Zornberg GL, Jick SS, Seshadri S, Drachman DA. 2000. Statins and the risk of

dementia. Lancet 356: 1627-1631.

Jithesh MN, Prashanth, SR, Siva prakash KR and Parida AK. 2006. Antioxidative

response mechanisms in halophytes: their role in stress defence. J Genet 85(3):

237-254.

Johnson GV, Stoothodd WH. 2004. Tau phosphorlyation in neuronal cell function and

dysfunction. J Cell Sci 117(24): 5721-5729.

Jorissen E, Prox J, Bernreuther C, Weber S, Schwanbeck R, Serneels L, Snellinx A,

Craessaerts K, Thathiah A, Tesseur I, Bartsch U, Weskamp G, Blobel CP,

Glatzel M, Strooper BD, Saftig P. 2010. The Disintegrin/Metalloproteinase

ADAM10 Is Essential for the Establishment of the Brain Cortex. J Neurosci

30(14): 4833-4844.

Jung HA, Lee EJ, Kim JS, Kang SS, Lee JH, Min BS, Choi JS. 2009. Cholinesterase

and BACE1 Inhibitory Diterpenoids from Aralia cordata. Arch Pharm Res

32(10): 1399-1408.

Kado NY, Eisenstadt LE. 1983. A simple modification of the Salmonella liquid

incubation assay: increased sensitivity for detecting mutagens in human urine.

Mutat Res 122: 25-32.

Kalaria RN, Maestre GE, Arizaga R, Friedland RP, Galasko D, Hall K, Luchsinger JA,

Ogunniyi A, Perry EK, Potocnik F, Prince M, Stewart R, Wimo A, Zhang ZX,

Antuono P. 2008. Alzheimer's disease and vascular dementia in developing

Page 25: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

368 References

countries: prevalence, management, and risk factors. Lancet Neurol 7(9): 812-

26.

Kamal A, Stokin GB, Yang Z, Xia CH, Goldstein LS. 2000. Axonal transport of

amyloid precursor protein is mediated by direct binding to the kinesin light

chain subunit of kinesin-I. Neuron 28(2): 449-459.

Kaminsky YG, Kosenko EA. 2008. Effects of amyloid-beta peptides on hydrogen

peroxide-metabolizing enzymes in rat brain in vivo. Free Radic Res 42(6): 564-

573.

Kaminsky YG, Marlatt MW, Smith MA, Kosenko EA. 2010. Subcellular and metabolic

examination of amyloid-β peptides in Alzheimer disease pathogenesis: Evidence

for Aβ (25-35). Exp Neurol 221(1): 26-37.

Karawita R, Siriwardhana N, Lee KW, Heo MS, Yeo IK, Lee YD, Jeon YJ. 2005.

Reactive oxygen species scavenging, metal chelation, reducing power and lipid

peroxidation inhibition properties of different solvent fractions from Hizikia

fusiformis. Eur Food Res Technol 220: 363-371

Kathiresan K, Bingham BL. 2001. Biology of mangrove and mangrove ecosystems.

Adv Mar Biol 40: 81‐251.

Kathiresan K. 1995. Rhizophora annamalayana: A new species of mangrove. Environ

Ecol 13(1): 240‐241.

Kathiresan K. 2000. A review of studies on Pichavaram mangrove, southeast India.

Hydrobiologia 430: 185‐205.

Kathiresan K. 2003. How do mangrove forests induce sedimentation? Rev Biol Trop 51:

355-360.

Kern JC, Kehrer JP. 2002. Acrolein-induced cell death: A caspaseinfluenced decision

between apoptosis and oncosis/necrosis. Chem Biol Interact 139: 79-95.

Khan MI, Atreja PP. 2001. Chemical composition of vegetable residues from agro

processing plants. Proceeding of the Animal Nutrition Conference, NDRI:

Karnal Abstr.# 071.

Khan RA, Khan MR, Sahreen S, Ahmed M. 2012. Evaluation of phenolic contents and

antioxidant activity of various solvent extracts of Sonchus asper (L.) Hill. Chem

Cent J 6:12.

Kihara T, Shimohama S. 2004. Alzheimer's disease and acetylcholine receptors. Acta

Neurobiol Exp 64: 99-105.

Kim DK, Lee KT, Baek NI, Kim SH, Park HW, Lim JP, Shin TY, Eom DO, Yang JH,

Eun JS. 2004. Acetylcholinesterase inhibitors from the aerial parts of Corydalis

speciosa. Arch Pharm Res 27: 1127-31.

Page 26: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

369 References

Kim HM, Um JY. 2007. Epigallocatechin-3-gallate suppresses NF-kappa B activation

and phosphorylation of p38 MAPK and JNK in human astrocytoma U373MG

cells. J Nutr Biochem 18(9): 587-596.

Kim HS, Kim EM, Lee JP, Park CH, Kim S, Seo JH, Chang KA, Yu E, Jeong SJ,

Chong YH, Suh YH. 2003. C-terminal fragments of amyloid precursor protein

exert neurotoxicity by inducing glycogen synthase kinase-3beta

expression. FASEB J 17: 1951-1953.

Kim HS, Lim JY, Sul D, Hwang BY, Won TJ, Hwang KW, Park SY. 2009.

Neuroprotective effects of the new diterpene, CBNU06 against beta-amyloid-

induced toxicity through the inhibition of NF-kappaB signaling pathway in

PC12 cells. Eur J Pharmacol 622: 25-31.

Kim HS, Park CH, Cha SH, Lee JH, Lee S, Kim Y, Rah JC, Jeong SJ, Suh YH. 2000.

Carboxyl-terminal fragment of Alzheimer‘s APP destabilizes calcium

homeostasis and renders neuronal cells vulnerable to excitotoxicity. FASEB J

14: 1508-1517.

Kim JY, Jung KJ, Choi JS, Chung HY. 2006. Modulation of the age-related nuclear

factor kappaB( NF-kappaB) pathway by hesperetin. Aging Cell 5: 401-411.

Kim M-J, Lee J, Seong A-R, Lee Y-H, Kim Y-J, Bae H-Y, Kim YJ, Jun WJ, Yoon H-

G. 2011. Neuroprotective effects of Eriobotrya japonica against b-amyloid-

induced oxidative stress and memory impairment. Food Chem Toxicol 49: 780-

784.

Kim SR, Sung SH, Lim DY, Kim H, Choi H, Park HK, Jew SS, Kim YC, Lee MK.

2000. Asiatic acid derivatives protect cultured neurons from glutamate-induced

excitotoxicity. Res Commun Mol Pathol Pharmacol 108: 75-86.

Kim YM, Park K, Jung SH, Choi JH, Kim WC, Joo GJ, Rhee IK. 2004. Chlorothalonil-

biotransformation by glutathione S-transferase of Escherichia coli. J Microbiol

42(1): 42-46.

King GD, Scott Turner R. 2004. Adaptor protein interactions: modulators of amyloid

precursor protein metabolism and Alzheimer's disease risk? Exp Neurol 185:

208-219.

Kirazov E, Kirazov L, Bigl V, Schliebs R. 2001. Ontogenetic changes in protein level

of amyloid precursor protein (APP) in growth cones and synaptosomes from rat

brain and prenatal expression pattern of APP mRNA isoforms in developing rat

embryo. Int. J. Dev. Neurosci 19(3): 287-296.

Kirkitadze MD, Kowalska A. 2005. Molecular mechanisms intiating amyloid beta-fibril

formation in Alzheimer‘s disease. Acta Biochim Pol 52(2): 417-423.

Page 27: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

370 References

Kojro E, Gimpl G, Lammich S, Marz W, Fahrenholz F 2001. Low cholesterol

stimulates the nonamyloidogenic pathway by its effect on the alpha secretase

ADAM 10. Proc Natl Acad Sci U S A 98(10): 5815-5820.

Kokpol U, Chavasiri W, Chittawong V, Miles DH. 1990. Taraxeryl

cis‐p‐hydroxycinnamate, a novel taraxeryl from Rhizophora apiculata. J Nat

Prod 53(4): 953‐955.

Koo EH, Sisodia SS, Archer DR, Martin LJ, Weidemann A, Beyreuther K, Fischer P,

Masters CL, Price DL. 1990a. Precursor of amyloid protein in Alzheimer

disease undergoes fast anterograde axonal transport. Proc Nat1 Acad Sci USA

87: 1561-1565.

Kopan R, Ilagan MXG. 2004. -Secretase: proteasome of the membrane? Nat Rev Mol

Cell 5: 499-504.

Koponen S, Taiminen T, Kairisto V, Portin R, Isoniemi H,Hinkka S, Tenovuo O. 2004.

APOE-14 predicts dementiabut not other psychiatric disorders after traumatic

braininjury. Neurology 63: 749-50.

Kornhuber J, Weller M. 1997. Psychotogenicity and N-methyl-D-aspartate receptor

antagonism: Implications for neuroprotective pharmacotherapy. Biol psychiatry

41(2): 135-44.

Kovacs DM. 2000. α2-Macroglobulin in late-onset Alzheimer's disease. Exp Gerontol

35(4): 473-79.

Kozurkova M, Hamulakova S, Gazova Z, Paulikova H, Kristian P. 2011. Neuroactive

Multifunctional Tacrine Congeners with Cholinesterase, Anti-Amyloid

Aggregation and Neuroprotective Properties. Pharmaceuticals 4: 382-418.

Krishnaveni S, Theymoli B, Sadasivam S. 1984. Phenol Sulpuric acid method. Food

Chem 15: 229.

Kubo T, Nishimura S, Kumagae Y, Kaneko Y. 2002. In vivo conversion of racemized

beta-amyloid ((D-Ser 26)A 1-40) to truncated and toxic fragments ((D-Ser

26)A 25-35/40) and fragment presence in the brains of Alzheimer‘s patients. J

Neurosci Res 70: 474-483

Kwak HM, Jeon SY, Sohng BH, Kim JG, Lee JM, Lee KB, Jeong HH, Hur JM, Kang

YH, Song KS. 2005. β-Secretase (BACE1)Inhibitors from Pomegranate (Punica

granatum) Husk. Arch Pharm Res 28(12): 1328-32.

Kweon SH, Kim Y, Choi HM. 2003. Grape extracts suppress the formation of

preneoplastic foci and activity of fatty acid synthase in rat liver. Exp Mol Med

35: 371-378.

Page 28: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

371 References

Kwok BH, Koh B, Ndubuisi MI, Elofsson M, Crews CM. 2001. The anti-infammatory

natural product parthenolide from the medicinal herb Feverfew directly binds to

and inhibits Ikappa kinase. Chem Biol 8: 759-766.

Kwon MO, Herrling P. 2006. List of drugs in development for neurodegenerative

disease. Neurodegener Dis 3: 148-186.

Lace GL, Wharton SB, Ince PG. 2007. A brief history of tau: the evolving view of the

microtubule-associated protein tau in neurodegenerative diseases. Clin

Neuropathol 26(2): 43-58.

Lakshmanan KK, Dhanalakshmi S. 1989. Phytochemical survey of Indian mangroves -

A preliminary screening. PNAS in India (B Biol Sci) 59(3): 345-347

Lambert JC, Heath S, Even G, Campion D, Sleegers K. 2009. Genome wide association

study identifies variants at CLU and CR1 associated with Alzheimer‘s disease.

Nat Genet 41: 1094-99.

Lattimer JM, Hau MD. 2010. Effects of Dietary Fiber and Its Components on Metabolic

Health. Nutrients 2(12): 1266-1289.

Laursen SE, Belknap JK. 1986. Intracerebroventricular injections in mice. Some

methodological refinements. J Pharmacol Methods 16: 355-357.

Lautraite S, Bigot-Lasserre D, Bars R, Carmichael N. 2003. Optimisation of cell-based

assays for medium throughput screening of oxidative stress. Toxicol in Vitro 17:

207-220.

Lazarov O, Lee M, Peterson DA, Sisodia SS. 2002. Evidence that synaptically released

beta-amyloid accumulates as extracellular deposits in the hippocampus of

transgenic mice. J Neurosci 22: 9785-9793.

Lee CL, Kuo TF, Wu CL, Wang JJ, Pan TM. 2010. Red Mold Rice Promotes

Neuroprotective sAPP Secretion Instead of Alzheimer‘s Risk Factors and

Amyloid Beta Expression in Hyperlipidemic Aβ40-Infused Rat. J Agric Food

Chem 58(4): 2230-2238.

Lee HG, Castellani RJ, Zhu X, Perry G, Smith MA. 2005. Amyloid-beta in Alzheimer‘s

disease: the horse or the cart? Pathogenic or protective. Int J Exp Patho. 86:

133-138.

Lee HJ, Seong YH, Bae KH, Kwon SH, Kwak HM, Nho SK, Kim KA, Hur JM, Lee

KB, Kang YH, Song KS. 2005. β-Secretase (BACE1) inhibitors from

Sanguisorbae Radix. Arch Pharmacal Res 28(7): 799-803.

Lee JC, Kim HR, Kim J, Jang YS. 2002. Antioxidant property of an ethanol extract of

the stem of Opuntia ficus-indica var Saboten. J Agric Food Chem 50: 6490-

6496.

Page 29: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

372 References

Lee JS, Jung WK, Jeong MH, Yoon TR, Kim HK. 2012. Sanguinarine induce apoptosis

of HT-29 human colon cancer cells via the regulation of Bax/Bcl-2 ratio and

caspase-9 dependant pathway. Int J Toxicol 31: 70-77.

Lee KY, Sung SH, Kim YC. 2003. New acetylcholinesterase-inhibitory pregnane

glycosides of Cynanchum atratum roots. Helvetica Chim Acta 86: 474-83.

Lee PL, Hsiung G-YR, Seitz D, Gill SS, Rochon PA. 2011. Cholinesterase inhibitors.

BCMJ 53(8): 404-408.

Lee SY, Lee JW, Lee H, Yoo HS, Yun YP, Oh KW, Ha TY, Hong JT. 2005. Inhibitory

effect of green tea extract on -amyloid-induced PC12 cell death by inhibition

of the activation of NF-B and ERK/p38 MAP kinase pathway through

antioxidant mechanisms. Mol Brain Res 140: 45-54.

Lee YH, Tharp WG, Maple RL, Nair S, Permana PA. 2008. Amyloid precursor protein

expression is upregulated in adipocytes in obesity. Obesity 16: 1493-1500.

Lee YL, Lin Y-C, Lee Y-C, Wang J-Y, Hsiue T-R, Guo yl. 2004. Glutathione S-

transferase P1 gene polymorphism and air pollution as interactive risk factors

for childhood asthma. Clin Exp Allergy 34(11): 1707-1713.

Lenart N, Szegedi V, Juha´ sz G, Kasztner A, Horvath J, Bereczki E, Toth ME, Penke

B, Santha M. 2012. Increased Tau Phosphorylation and Impaired Presynaptic

Function in Hypertriglyceridemic ApoB-100. Transgenic Mice 7(9): e46007e.

Levine RL, Garland D, Oliver CN, Amici A, Climent I, Lenz AG, Ahn BW, Shaltiel S,

Stadtman ER. 1990. Determination of carbonyl content of oxidatively modified

proteins, Methods enzymol 186: 464-478.

Levy-Lahad E, Wasco W, Poorkaj P, Romano DM, Oshima J, Pettingell WH, Yu CE,

Jondro PD, Schmidt SD, Wang K. 1995a. Candidate gene for the chromosome 1

familial Alzheimer‘s disease locus. Science 269: 973-77

Leyssen M, Ayaz D, Hebert SS, Reeve S, De Strooper B, Hassan BA. 2005. Amyloid

precursor protein promotes post-developmental neurite arborization in the

Drosophila brain. EMBO J 24: 2944-2955.

Li R, Lindholm K, Yang LB, Yue X, Citron M, Yan R, Beach T, Sue L, Sabbagh M,

Cai H, Wong P, Price D, Shen Y. 2004. Amyloid beta peptide load is correlated

with increased beta-secretase activity in sporadic Alzheimer's disease patients.

Proc Natl Acad Sci USA 101(10): 3632-3637.

Li X, Wu X, Huang L. 2009. Correlation between Antioxidant Activities and Phenolic

Contents of Radix Angelicae Sinensis (Danggui). Molecules 14: 5349-5361.

Page 30: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

373 References

Li Z, Jo J, Jia J-M, Lo S-C, Whitcomb D-J, Jiao S, Cho K, Sheng M. 2010. Caspase-3

Activation via Mitochondria Is Required for Long-Term Depression and AMPA

Receptor Internalization. Cell 141(5): 859-871.

Liang Y, Tang X. 2006. Comparative studies of huperzine A, donepezil, and

rivastigmine on brain acetylcholine, dopamine, norepinephrine, and 5-

hydroxytryptamine levels in freely-moving rats. Acta Pharmacol Sin 27: 1127-

1136.

Lichtentaler HK, Wellburn AR. 1985. Determination of Total Carotenoids and

Chlorophylls A and B of Leaf in Different Solvents. Biochem Soc Trans 11:

591-592.

Liebezeit G, Rau MT. 2006. New Guinean mangroves — traditional usage and

chemistry of natural products. Senckenbergiana maritime 36(1): 1-10.

Lim GP, Chu T, Yang F, Beech W, Frautschy SA, Cole GM. 2001. The Curry Spice

Curcumin Reduces Oxidative Damage and Amyloid Pathology in an Alzheimer

Transgenic Mouse. J Neurosci 21(21): 8370-8377.

Lim JY, Won TJ, Hwang BY, Kim HR, Hwang KW, Sul D, Park SY. 2010. The new

diterpene isodojaponin D inhibited LPS-induced microglial activation through

NF-kB and MAPK signaling pathways. Eur J Pharmacol 642: 10-18.

Limpeanchob N, Jaipan S, Rattanakaruna S, Phrompittayarat W, Ingkaninan K. 2008.

Neuroprotective effect of Bacopa monnieri on beta-amyloid-induced cell death.

J Ethnopharmacol 120(1): 112-117.

Lipinski B 2011. Hydroxyl Radical and Its Scavengers in Health and Disease. 2011.

Oxid Med Cell Longev Article ID 809696, 9 pp., doi:10.1155/2011/809696.

Liu L, Zhu W, Zhang ZS, Yang T, Grant A, Oxford G, Simon SA. 2004. Nicotine

Inhibits Voltage-Dependent Sodium Channels and Sensitizes Vanilloid

Receptors. J Neurophysiol 91: 1482-1491.

Liu R, Gao M, Qiang G-F, Zhang T-T, Lana X, Ying J, Dua G-H. 2009. The anti-

amnesic effects of luteolin against amyloid β25-35 peptide-induced toxicity in

mice involve the protection of neurovascular unit. Neuroscience 162(4): 1232-

1243.

Liu R, Wu C-X, Zhou D, Yang F, Tian S, Zhang L, Zhang T, Du G. 2012. Pinocembrin

protects against -amyloid-induced toxicity in neurons through inhibiting

receptor for advanced glycation end products (RAGE)- independent signaling

pathways and regulating mitochondrion-mediated apoptosis. BMC Med 10:105

Page 31: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

374 References

Liu R. 2003. Reversal of age-related learning deficits and brain oxidative stress in mice

with superoxide dismutase/catalase mimetics. Proc Natl Acad Sci USA 100:

8526-8531.

Liu WB, Zhou J, Qu Y, Li X, Lu CT, Xie KL, Sun XL, Fei Z. 2010. Neuroprotective

effect of osthole on MPP+-induced cytotoxicity in PC12 cells via inhibition of

mitochondrial dysfunction and ROS production. Neurochem Int 57(3): 206-215.

Lizcano LJ, Viloria-Bernal M, Vicente F, Berrueta LA, Gallo B, Martínez-Cañamero

M, Ruiz-LarreaMB, Ruiz-Sanz JI. 2012. Lipid Oxidation Inhibitory Effects and

Phenolic Composition of Aqueous Extracts from Medicinal Plants of Colombian

Amazonia. Int J Mol Sci 13: 5454-5467.

López S, Bastida J, Viladomat F, Codina C. 2002. Acetylcholinesterase inhibitory

activity of some Amaryllidaceae alkaloids and Narcissus extracts. Life Sci 71:

2521-29.

Lopez-Perez E, Zhang Y, Frank SJ, Creemers J, Seidah N, Checler F. 2001.

Constitutive alpha-secretase cleavage of the beta-amyloid precursor protein in

the furin-deficient LoVo cell line: involvement of the pro-hormone convertase 7

and the disintegrin metalloprotease ADAM10. J Neurochem 76: 1532-1539.

Lovell MA, Ehmann WD, Butler SM, Markesbery WR. 1995. Elevated thiobarbituric

acid-reactive substances and antioxidant enzyme activity in the brain in

Alzheimer's disease. Neurology 45(8): 1594-1601.

Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. 1951. Protein measurement with the

Folin phenol reagent. J Biol Chem 193(1): 265-275.

Lu DC, Shaked GM, Masliah E, Bredesen DE, Koo EH. 2003. Amyloid beta protein

toxicity mediated by the formation of amyloid-beta protein precursor

complexes. Ann Neurol 54: 781-789.

Lu DY, Tang CH, Chen YH, Wei IH. 2010. Berberine suppresses neuroinflammatory

responses through AMP-activated protein kinase activation in BV-2 microglia. J

Cell Biochem 110: 697-705.

Lu P, Mamiya T, Lu LL, Mouri A, Zou LB, Nagai T, Hiramatsu M, Ikejima T,

Nabeshima T. 2009. Silibinin prevents amyloid β peptide-induced memory

impairment and oxidative stress in mice. Br J Pharmacol 157(7): 1270-1277.

Luchsinger JA, Tang MX, Miller J, Green R, Mayeux R. 2007. Relation of higher folate

intake to lower risk of Alzheimer disease in the elderly. Arch Neurol 64: 86-92.

Luo W, Dou F, Rodina A, Chip S, Kim J, Zhao Q, Moulick K, Aguirre J, Wu N,

Greengard P, Chiosis G. 2007. Roles of heat-shock protein 90 in maintaining

Page 32: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

375 References

and facilitating the neurodegenerative phenotype in tauopathies. Proc Natl Acad

Sci USA 104(22): 9511-9516.

Luo W, Sun W, Taldone T, Rodina A and Chiosis G. 2010. Heat shock protein 90 in

neurodegenerative Diseases. Mol Neurodegener 5:24.

Luo Y, Smith JV, Paramasivam V, Burdick A, Curry KJ, Buford JP, Khan I, Netzer

WJ, Butk HXP. 2002. Inhibition of amyloid- aggregation and caspase-

3activation by the Ginkgo biloba extract EGb761. PNAS 99(19): 12197-12202.

Lustbader JW, Cirilli M, Lin C, Xu HW, Takuma K, Wang N, Caspersen C, Chen X,

Pollak S, Chaney M, Trinchese F, Liu S, Gunn-Moore F, Lue L, Walker DG,

Kuppusamy P, Zewier ZL, Arancio O, Stern D, Yan SS, Wu H. 2004. ABAD

Directly Links Aß to Mitochondrial Toxicity in Alzheimer's Disease. Science

304(5669): 448-452.

Lv L, Yang QY, Zhao Y, Yao CS, Sun Y, Yang EJ, Song KS, Mook-Jung I, Fang WS.

2008. BACE1 (beta-secretase) inhibitory chromone glycosides from Aloe vera

and Aloe nobilis. Planta Med 74(5): 540-545.

Lyras L, Cairns NJ, Jenner A, Jenner P, Halliwell B.1997. An assessment of oxidative

damage to proteins, lipids, and DNA in brains from patients with Alzheimer‘s

disease. J Neurochem 68: 2061-2069.

Ma Q, Yang F, Rosario ER, Ubeda OJ, Beech W, Gant DJ, Chen PP, Hudspeth B, Chen

C, Zhao Y, Vinters HV, Frautschy SA, Cole GM. Amyloid Oligomers Induce

Phosphorylation of Tau and Inactivation of Insulin Receptor Substrate via c-Jun

N-Terminal Kinase Signaling: Suppression by Omega-3 Fatty Acids and

Curcumin. J Neurosci 29(28): 9078-9089.

Mahley RW, Weisgraber KH, Huang Y. 2006. Apolipoprotein E4: a causative factor

and therapeutic target in neuropathology, including Alzheimer's disease. Proc

Natl Acad Sci USA 103(15): 5644-5651.

Manczak M, Mao P, Calkins MJ, Cornea A, Reddy AP, Murphy MP, Szeto HH, Park

B, Reddy PH. 2010. Mitochondria-Targeted Antioxidants Protect Against

Amyloid-β Toxicity in Alzheimer's Disease Neurons. J Alzheimer's Dis 20(2):

609-631.

Mandal RN, Naskar KR. 2008. Diversity and classification of Indian mangroves: a

review. Trop Ecol 49(2): 131-46.

Marchesi VT. 2012. Alzheimer's disease 2012: the great amyloid gamble. Am J Pathol

180(5): 1762-1767.

Page 33: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

376 References

Marcocci L, Maguire JJ, Droy-Lefaix MT, Packer L. 1994a. The nitric oxide-

scavenging properties of Ginkgo biloba extract EGb 761. Biochem Biophys Res

Commun 15: 748-755.

Marcus DL, Strafaci JA, Freedman ML. 2006. Differential neuronal expression of

manganese superoxide dismutase in Alzheimer's disease. Med Sci Monit 12:

BR8-BR14.

Margolis RL, Rudnicki DD, Holmes SE. 2005 Huntington‘s Disease Like-2: Review

and Update. Acta Neurol Taiwan 14: 1-8.

Markesbery WR, Lovell MA. 1988. Four-hydroxnonenal, a product of lipid

peroxidation, is increased in the brain in Alzheimer‘s disease. Neurobiol Aging

19: 33-36.

Maron DM, Ames BN. 1983. Revised methods for the Salmonella mutagenicity. Mutat

Res 113(3-4): 173-215.

Marshall GA, Fairbanks LA, Tekin S, Vinters HV, Cummings JL. 2007. Early onset

Alzheimer‘s disease is associated with greater pathologic burden. J Geriatr

Psychiatry Neurol 20: 29-33.

Martin D, Salinas M, Lopez-Valdaliso R, Serrano E, Recuero M, Cuadrado A. 2001.

Effect of the Alzheimer amyloid fragment Abeta(25-35) on Akt/PKB kinase and

survival of PC12 cells. J Neurochem 78:1000-1008.

Marumoto S, Miyazawa M. 2010. Beta-secretase inhibitory effects of furanocoumarins

from the root of Angelica dahurica. Phytother Res 24: 510-513.

Masliah E, Terry R. 1993. The role of synaptic proteins in the pathogenesis of disorders

of the central nervous system. Brain Pathol 3: 77-85.

Massoud F, Desmarais JE, Gauthier S. 2011. Switching cholinesterase inhibitors in

older adults with dementia. Int Psychogeriatr 23(3): 372-378.

Matharu B, Gibson G, Parsons R, Huckerby TN, Moore SA, Cooper LJ, Millichamp R,

Allsop D, Austen B. 2009. Galantamine inhibits beta-amyloid aggregation and

cytotoxicity. J Neurol Sci 280(1-2): 49-58.

Mathuranath PS, George A, Ranjith N, Justus S, Kumar MS, Menon R, Sarma PS,

Verghese J. 2012. Incidence of Alzheimer‘s disease in India: A 10 year follow

up study. Neurol India 60(6): 625-630.

Matsubara E, Shoji M, Murakami T, Kawarabayashi T, Abe K. 2003. Alzheimer's

disease and melatonin. Int Congr Ser 1252: 395-398.

Matsui T, Ingelsson M, Fukumoto H, Ramasamy K, Kowa H, Frosch MP, Irizarry MC,

Hyman BT. 2007. Expression of APP pathway mRNAs and proteins in

Alzheimer‘s disease. Brain Res 1161: 116-123.

Page 34: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

377 References

Mattson MP, Magnus T. 2006. Ageing and neuronal vulnerability. Nat Rev Neurosci

7(4): 278-294.

Mattson MP. 2004. Pathways towards and away from Alzheimer‘s disease.

Nature 430(7000): 631-9.

Maurer K, Volk S, Gerbaldo H.1997. Auguste D and Alzheimer's

disease. Lancet 349: 1546-1549.

Maurice T, Lockhart BP, Privat A. 1996. Amnesia induced in mice by centrally

administered -amyloid peptides involves cholinergic dysfunction. Brain Res

706: 181-193.

May MJ, Madge LA. 2007. Caspase Inhibition Sensitizes Inhibitor of NF-B Kinase -

deficient Fibroblasts to Caspase-independent Cell Death via the Generation of

Reactive Oxygen Species. J Biol Chem 282(22): 16105-16116.

May PC, Dean RA, Lowe SL, Martenyi F, Sheehan SM, Boggs LN, Monk SA, Mathes

BM, Mergott DJ, Watson BM, Stout SL, Timm DE, LaBell ES, Gonzales CR,

Nakano M, Jhee SS, Yen M, Ereshefsky L, Lindstrom TD, Calligaro DO, Cocke

PJ, Greg Hall D, Friedrich S, Citron M, Audia JE. Robust Central Reduction of

Amyloid-in Humans with a Orally Available, Non-Peptidic-Secretase Inhibitor.

J Neurosci 16: 6507-16516.

Mayeux R, Stern Y. 2012. Epidemiology of Alzheimer Disease. Cold Spring Harb

Perspect Med 2: a006239.

Maynard CJ, Bush AI, Masters CL, Cappai R, Li QX. 2005. Metals and amyloid-beta in

Alzheimer's disease. Int J Exp Pathol 86: 147-159.

McCullagh CD, Craig D, McIlroy SP, Passmore AP. 2001. Risk factors for dementia.

Adv Psychiatric Treatm 7: 24-31.

McGeer PL, McGeer EG. 2007. NSAIDS and Alzheimer‘s disease: epidemiological,

animal model and clinical studies. Neurobiol Aging 28(5): 639-647.

Mckeith IG. 2002. Dementia with Lewy bodies. Br J Psychiatry 180: 144-147.

Mehta M, Adem A, Sabbagh M. 2012. New Acetylcholinesterase Inhibitors for

Alzheimer's Disease. Int J Alzheimers Dis Article ID 728983, 8 pages

doi:10.1155/2012/728983

Mei Z, Zhang F, Tao L, Zheng W, Cao Y, Wang Z, Tang S, Le K, Chen S, Pi R, Liu P.

2009. Cryptotanshinone, a compound from Salvia miltiorrhiza modulates

amyloid precursor protein metabolism and attenuates beta-amyloid deposition

through upregulating alpha-secretase in vivo and in vitro. Neurosci Lett 452(2):

90-95.

Page 35: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

378 References

Melo JB, Agostinho P, Oliveira CR. 2003. Involvement of oxidative stress in the

enhancement of acetylcholinesterase activity induced by amyloid beta-peptide.

Neurosci Res 45(1): 117-127.

Meng G, Liu R, Gao M, Wang Y, Yu X, Xuan Z, Sun J, Yang F, Wu C, Du G. 2011.

Pinocembrin attenuates blood-brain barrier injury induced by global cerebral

ischemia-reperfusion in rats. Brain Res 1391: 93-101.

Merlos-Suarez A, Ruiz-Paz S, Baselga J, Arribas J. 2001. Metalloprotease-dependent

protransforming growth factor -ectodomain shedding in the absence of tumor

necrosis factor--converting enzyme. J Biol Chem 276: 48510–48517.

Meunier J, Ieni J, Maurice T. 2006. The anti-amnesic and neuroprotective effects of

donepezil against amyloid β 25-35 peptide-induced toxicity in mice involve an

interaction with the σ1 receptor. Br J Pharmacol 149(8): 998-1012.

Miech RA, Breitner JCS, Zandi PP, Khachaturian AS, Anthony JC, Mayer L. 2002.

Incidence of AD may decline in the early 90s for men, later for women : The

Cache County study. Neurol 58(2): 209-18.

Miklossy J. 2011. Emerging roles of pathogens in Alzheimer disease. Exp Rev Mol Med

13: e30. doi: 10.1017/S1462399411002006.

Milano J, McKay J, Dagenais C, Foster-Brown L, Pognan F, Gadient R, Jacobs RT,

Zacco A, Greenberg B, Ciaccio PJ. 2004. Modulation of Notch Processing by -

Secretase Inhibitors Causes Intestinal Goblet Cell Metaplasia and Induction of

Genes Known to Specify Gut Secretory Lineage Differentiation. Toxicol Sci 82:

341-358.

Milligan CE. 2000. Caspase cleavage of APP results in a cytotoxic proteolytic

peptide. Nat Med 6: 385-386.

Mills S, Bone K. 2000. Principles and Practice of Phytotherapy: Modern herbal

medicine. Churchill Livingstone: Edinburgh.

Millward DJ. 2012. Amino acid scoring patterns for protein quality assessment. Br J

Nutr 108(2): S31-43.

Mitchell ES, Neumaier JF. 2005. 5-HT6 receptors: a novel target for cognitive

enhancement, Pharmacol Ther 108(3): 320-333.

Miyamoto T, Miyamoto M, Inoue Y, Usui Y, Suzuki K, Hirata K. 2006. Reduced

cardiac 123I-MIBG scintigraphy in idiopathic REM sleep behavior disorder.

Neurology 67(12): 2236-2238.

Momeni P, Ferrari R. 2010. Genetic and Blood Biomarkers of Alzheimer‘s Disease.

The Open Nuc Med J 2: 12-24.

Page 36: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

379 References

Montiel T, Quiroz-Baez R, Massieu L, Arias C. 2006. Role of oxidative stress on beta-

amyloid neurotoxicity elicited during impairment of energy metabolism in the

hippocampus: protection by antioxidants. Exp Neurol 200(2): 496-50.

Mori C, Spooner ET, Wisniewski KE, Wisniewski TM, Yamaguchi H, Saido TC, Tolan

DE, Selkoe DJ, Lemere CA. 2002. Intraneuronal Aβ42 accumulation in Down

syndrome brain. Amyloid 9(2): 88-102.

Morishima Y, Gotoh Y, Zieg J, Barrett T, Takano H, Flavell R, Davis RJ, Shirasaki Y,

and Greenberg ME. 2001. -Amyloid Induces Neuronal Apoptosis Via a

Mechanism that Involves the c-Jun N-Terminal Kinase Pathway and the

Induction of Fas Ligand. J Neurosci 21(19): 7551-7560.

Moro MA, Darley-Usmar VM, Goodwin DA, Read NG, Zamorapino R, Feelisch M,

Radomski MW, Moncada S. 1994. Paradoxical fate and biological action of

peroxynitrite on human platelets. Proc Natl Acad Sci USA 91: 6702-6706.

Morris MC, Evans DA, Bienias JL, Tangney CC, Wilson RS. 2002. Vitamin E and

cognitive decline in older persons. Arch Neurol 59:1125-32.

Mortelmans K, Zeiger E. 2000. The Ames Salmonella/microsome mutagenicity assay.

Mutat Res Fund Mol Mech Mut 455: 29-60.

Mosmann T. 1983. Rapid colorimetric assay for cellular growth and survival:

application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55-

63.

Moussaieff A, Shohami E, Kashman Y, Fride E, Schmitz ML, Renner F. 2007.

Incensole acetate, a novel anti-inflammatory compound isolated from Boswellia

resin, inhibits nuclear factor-kappa B activation. Mol Pharmacol 72: 1657-1664.

Mu L, Kou J, Zhu D, Yu B. 2007. Comparison of neuroprotective effects of flavonoids,

terpenoids, and their combinations from Ginkgo biloba on Ischemia-

reperfusion-injured mice. Pharm Biol 45: 728-733.

Mukherjee PK, Kumar V, Mal M, Houghton PJ. 2007. Acetylcholinesterase inhibitors

from plants. Phytomedicine 14: 289-300.

Mukinda JT, Syce JA. 2007. Acute and chronic toxicity of the aqueous extract of

Artemisia afra in rodents. J Ethnopharmacol 112: 138-144.

Munoz-Ruiz P, Rubio L, Garcia-Palomero E, Dorronsoro I, del MonteMillan M,

Valenzuela R, Usan P, de Austria C, Bartolini M, Andrisano V, Bidon-Chanal

A, Orozco M, Luque FJ, Medina M, Martinez A. 2005. Design, synthesis, and

biological evaluation of dual binding site acetylcholinesterase inhibitors: new

disease-modifying agents for Alzheimer‘s disease. J Med Chem 48: 7223-7233.

Page 37: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

380 References

Muralidharan P, Ravi Kumar V, Balamurugan G. 2010. Protective effect of Morinda

citrifolia fruits on β-amyloid (25-35) induced cognitive dysfunction in mice: An

experimental and biochemical study. Phytother Res 24(2): 252-258.

Muthaiyah B, Essa MM, Chauhan V, and Chauhan A. 2011. Protective Effects of

Walnut Extract Against Amyloid Beta Peptide-Induced Cell Death and

Oxidative Stress in PC12 Cells. Neurochem Res 36(11): 2096-2103.

Nadeau A, Roberge AG. 1988. Effects of Vitamin B12 supplementation on choline

acetyltransferase activity in catbrain. Int J Vit Nutr Res 58: 402-406

Nakajima T, Takayama T, Miyanishi K, Nobuoka A, Hayashi T, Abe T, Kato J, Sakon

K, Naniwa Y, Tanabe H, Niitsu Y. Reversal of Multiple Drug Resistance in

Cholangiocarcinoma by the Glutathione S-Transferase-π-Specific Inhibitor O1-

Hexadecyl-γ-glutamyl-S-benzylcysteinyl-D-phenylglycine Ethylester. J

Pharmacol Exp Therap 306(3): 861-869.

Nakashima H, Ishihara T, Suguimoto P, Yokota O, Oshima E, Kugo A, Terada S,

Hamamura T, Trojanowski JQ, Lee VM, Kuroda S. 2005. Chronic lithium

treatment decreases tau lesions by promoting ubiquitination in a mouse model of

tauopathies. Acta Neuropathol 110: 547-556.

Nakashima H, Ishihara T, Yokota O, Terada S, Trojanowski JQ, Lee VM, Kuroda S.

2004. Effects of alpha-tocopherol on an animal model of tauopathies. Free

Radic Biol Med 37: 176-186.

Narasinga Rao BS. 2003. Bioactive phytochemicals in Indian foods and their potential

in health promotion and disease prevention. APJCN 12 (1): 9-22.

Navarro-González I, Garciá-Valverde V, Garciá-Alonso J, Periago MJ. 2011. Chemical

profile, functional and antioxidant properties of tomato peel fibre. Food Res

Inter 44(5): 1528-15355.

Ness S, Raffi M, Aisen P, Krams M, Wilvermna W, Manji H. 2011. Down's syndrome

and Alzheimer's disease: towards secondary prevention. Nat Rev Drug

Discov 11: 655-656.

Nie F, Zhang X, Qi Q, Yang L, Yang Y, LiuW, Lu N, Wu Z, You Q, Guo Q. 2009.

Reactive oxygen species accumulation contributes to gambogic acid-induced

apoptosis in human hepatoma SMMC-7721 cells. Toxicology 260(1-3): 60-67.

Nielsen SS. 2010. Determination of moisture content. In: Food analysis laboratory

manual. Chapter 3 (2nd

ed.) Springer: Dordrecht, Heidelberg, London; 17-24.

Nikolaev A, McLaughlin T, O‘Leary DD, Tessier-Lavigne M. 2009. APP binds DR6 to

trigger axon pruning and neuron death via distinct caspases. Nature 457(7232):

981-989.

Page 38: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

381 References

Nishimoto I, Okamoto T, Matsuura Y, Takahashi S, Okamoto T, Murayama Y, Ogata E

1993. Alzheimer amyloid protein precursor complexes with brain GTP-binding

protein G(o). Nature 362: 75-79.

Nunan J, Small DH. 2000. Regulation of APP cleavage by , , -secretase. 483 (1): 6-

10.

Nussbaum RL, Ellis CE. 2003. Alzheimer‘s disease and Parkinson‘s disease. N Engl J

Med. 348(14): 1356-64.

Nutrient requirements and recommended dietary allowances for Indians –RDA (2010).

A Report of the Expert Group of the Indian Council of Medical Research,

National institute of nutrition, ICMR, Hyderabad

Ochu EE, Rothwell NJ, Waters CM. 1998. Caspases mediate 6-hydroxydopamine-

induced apoptosis but not necrosis in PC12 cells. J Neurochem 70: 2637-2640.

Ohno M, Sametsky EA, Younkin LH, Oakley H, Younkin SG, Citron M, Vassar

R, Disterhoft JF. 2004. BACE1 deficiency rescues memory deficits and

cholinergic dysfunction in a mouse model of Alzheimer's

disease. Neuron 41: 27-33.

Ohsawa I, Takamura C, Kohsaka S. 2001. Fibulin-1 binds the amino-terminal head of

beta-amyloid precursor protein and modulates its physiological function. J

Neurochem 76: 1411-1420.

Oide T, Kinoshita T, Arima K. Regression stage senile plaques in the natural course of

Alzheimer‘s disease. Neuropathol Appl Neurobiol 32(5): 539-556.

Olgiati P, Politis AM, Oaoadimitriou GN, Ronchi DD, Serretti A. 2011. Genetics of

Late-Onset Alzheimer‘s Disease: Update from the Alzgene Database and

Analysis of Shared Pathways. Int J Alzheimers Dis Article ID 832379, 14 pp.,

doi:10.4061/2011/832379.

Olichney JM, Hansen LA, Hoffstetter CR, Lee JH, Katzman R, Thal LJ. 2000.

Association between severe cerebral amyloid angiopathy and cerebrovascular

lesions in Alzheimer disease is not a spurious one attributable to apolipoprotein

E4. Arch Neurol 57: 869-74.

Olivares D, Deshpande VK, Shi Y, Lahiri DK, Greig NH, Rogers JT, Huang X. 2012.

N-methyl D Aspartate NMDA receptor antagonists and memantine treatment for

Alzheimer‘s disease, vascular dementia and Parkinson‘s disease. Curr

Alzheimer Res 9(6): 746-758.

Olson H, Betton G, Robinson D, Thomas K, Monro A, Kolaja G, Lilly P, Sanders J,

Sipes G, Bracken W, Dorato M, Deun KV, Smith P, Berger B, Heller A. 2000.

Page 39: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

382 References

Concordance of toxicity of pharmaceuticals in humans and in animals. Regul

Toxicol Pharmacol 32: 56-67.

Omotayo AE, Ojo OY, Amund OO. 2012. Crude Oil Degradation by Microorganisms

in Soil Composts. Res J Microbiol 7: 209-218.

Ono K, Condron MM, Ho L, Wang J, Zhao W, Pasinetti GM, Teplow DB. 2008.

Effects of Grape Seed-derived Polyphenols on Amyloid-Protein Self-assembly

and Cytotoxicity. J Biol Chem 283(47): 32176-32187.

Ono K, Hasegawa K, Naiki H, Yamada M. 2004a. Antiamyloidogenic activity of tannic

acid and its activity to destabilize Alzheimer‘s beta amyloid fibrils in vitro.

Biochim Biophys ACTA 1690: 193-202.

Ono K, Hasegawa K, Naiki H, Yamada M. 2004b. Curcumin has potent anti-

amyloidogenic effects for Alzheimer‘s beta amyloid fibrils in vitro. J Neurosci

Res 75: 742-750.

Ordonez, AAL, Gomez J.D, Vattuone MA, Lsla ML. 2006. Antioxidant activities of

Sechium edule ( Jacq.) swartz extracts. Food Chem 97: 452-458.

Orhan I, Sener B, Choudhary MI, Khalid A. 2004. Acetylcholinesterase and

butyrylcholinesterase inhibitory activity of some Turkish medicinal plants. J

Ethnopharmacol 91: 57-60.

Osabor VN, Egbung GE, Okafor PC. 2008. Chemical Profile of Nypa fruiticans from

Cross River Estuary, South Eastern Nigeria. Pak J Nutr 7 (1): 146-150.

Oyaizu M. 1986. Studies on product of browning reaction prepared from glucose

amine. Jpn J Nutr 44: 307-315.

Padayachee E, Ngqwala N, Chris G. Whiteley. 2012. Association of β-amyloid peptide

fragments with neuronal nitric oxide synthase: Implications in the etiology of

Alzheimers disease. J Enzyme Inhib Med Chem 27(3): 356-364.

Padmanabhan J, Levy M, Dickson DW, Potter H. 2006. Alpha1-antichymotrypsin, an

inflammatory protein over expressed in Alzheimer‘s disease brain, induces tau

phosphorylation in neurons. Brain 129: 3020-3034.

Paglia DE, Valentine WN.1967. Studies on the quantitative and qualitative

characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 70:158-

169

Palmer T. 1995. Understanding Enzymes. 4th (ed.), Prentice Hall/Ellis Horwood:

London; 398pp.

Paoletti F, Mocali A. 1990. Determination of superoxide dismutase activity by purely

chemical system based on NAD(P)H oxidation. Meth Enzymol 186: 209-265.

Page 40: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

383 References

Papandreou MA, Kanakis CD, Polissiou MG, Efthimiopoulos S, Cordopatis P, Garity

M, Fotini Lamari FN. 2006. Inhibitory Activity on Amyloid-â Aggregation and

Antioxidant Properties of Crocus sativus Stigmas Extract and Its Crocin

Constituents J Agric Food Chem 54: 8762−8768.

Park J, Cho. 2009. Anti-inflammatory effects of ginsenosides from Panax ginseng and

their structural analogs. Afr J Biotechnol 8(16): 3682-3690.

Park JW, Youn JC, Kwon OS, Jang YY, Han ES, Lee CS. 2002. Protective effect of

serotonin on 6-hydroxydopamine- and dopamine-induced oxidative damage of

brain mitochondria and synaptosomes and PC-12 cells. Neurochem Int 40: 223-

233.

Park SA, Shaked GM, Bredesen DE, Koo EH. 2009. Mechanism of cytotoxicity

mediated by the C31 fragment of the amyloid precursor protein. Biochem

Biophys Res Commun 388: 450-455.

Park SY, Kim HS, Cho EK, Kwon BY, Phark, Hwang KW, Sul D. 2008. Curcumin

protected PC12 cells against beta-amyloid-induced toxicity through the

inhibition of oxidative damage and tau hyperphosphorylation. Food Chem

Toxicol 46(8): 2881–2887

Parnham MJ, Wetzig H. 1993. Toxicity screening of liposomes. Chem Phys Lipids

64(1-3): 263-274.

Pasinetti GM, Eberstein JA. 2008. Metabolic syndrome and the role of dietary lifestyles

in Alzheimer‘s disease. J Neurochem 106(4): 1503-1514.

Patten DA, Germain M, Kelly MA, Slack RS. 2010. Reactive oxygen species: stuck in

the middle of neurodegeneration. J Alzheimer's Dis 20(2): 357-367.

Patterson C, Feightner J, Garcia A, MacKnight C. 2007. General risk factors for

dementia: a systematic evidence review. Alzheimers Dement 3: 341-347.

Pavlik VN, · Doody RS, Rountree SD, · Darby EJ. 2009. Vitamin E Use Is Associated

with Improved Survival in an Alzheimer‘s Disease Cohort. Dement Geriatr

Cogn Disord 28: 536-540.

Pereira C, Ferreiro E, Cardoso SM, de Oliveira CR. 2004. Cell degeneration induced by

amyloid-β peptides. J Mol Neurosci 23(1-2): 97-104.

Perini G, Bianca VD, Politi V, Valle GD, Dal-Pra I, Rossi F, Armato U. 2002. Role of

p75 Neurotrophin Receptor in the Neurotoxicity by β-amyloid Peptides and

Synergistic Effect of Inflammatory Cytokines. JEM 195(7): 907-918.

Perlson E, Maday S, Fu MM, Moughamian AJ, Holzbaur EL. 2010. Retrograde axonal

transport: Pathways to cell death? Trends Neurosci 33: 335-44.

Page 41: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

384 References

Perron NR, Brumaghim JL. 2009. A review of the antioxidant mechanisms of

polyphenol compounds related to iron binding. Cell Biochem Biophys 53(2): 75-

100.

Perry E, Walker M, Grace J, and Perry R. 1999. Acetylcholine in mind: a

neurotransmitter correlate of consciousness? Trends Neurosci 22: 273-280.

Perry EK, Pickering AT, Wang WW, Houghton PJ, Perry NSL. 1998. Medicinal plants

and Alzheimer‘s disease: integrating ethnobotanical and contemporary scientific

evidence. J Altern Complement Med 4: 419-28.

Perry LM. 1980. Medicinal plants of east and Southeast Asia. MIT Press: Cambridge.

Perry N, Court G, Bidet N, Court J, Perry E. 1996. European herbs with cholinergic

activities: potential in dementia therapy. Int J Geriatr Psychiatry 11: 1063-1069.

Perry NSL, Houghton PJ, Jenner P, Keith A, Perry EK. 2002. Salvia lavandulaefolia

essential oil inhibits cholinesterase in vivo. Phytomedicine 9: 48-51.

Perry NSL, Houghton PJ, Theobald A, Jenner P, Perry EK. 2000. In vitro inhibition of

human erythrocyte acetylcholinesterase by Salvia lavandulaefolia essential oil

and constituent terpenes. J Pharm Pharmacol 52: 895-902.

Petit A, Pasini A, Alves Da Costa C, Ayral E, Hernandez JF, Dumanchin-Nojock C,

Phiel CJ, Marambaud P, Wilk S, Farzan M, Fulcrand P, Martinez J, Andrau D,

Checler F. 2003. JLK isocoumarin inhibitors: Selective gamma-secretase

inhibitors that do not interfere with notch pathway in vitro or in vivo. J Neurosci

Res 74(3): 370-377.

Pi R, Mao X, Chao X, Cheng Z, Liu M, DuanX, Ye M, Chen X, Mei Z, Liu P, Li W,

Han Y. 2012. Tacrine-6-Ferulic Acid, a Novel Multifunctional Dimer,Inhibits

Amyloid--Mediated Alzheimer‘s Disease- Associated Pathogenesis In Vitro

and In Vivo. PLoS one 7(2): e31921.

Piermartiri TC, Figueiredo CP, Rial D, Duarte FS, Bezerra SC, Mancini G, de Bem AF,

Prediger RD, Tasca CI. 2010. Atorvastatin prevents hippocampal cell death,

neuroinflammation and oxidative stress following amyloid-β (1-40)

administration in mice: evidence for dissociation between cognitive deficits and

neuronal damage. Exp Neurol 226: 274-284.

Pietropaolo S, Sun Y, Li R, Brana C, Feldon J, Yee BK. 2009. Limited impact of social

isolation on Alzheimer-like symptoms in a triple transgenic mouse model.

Behav Neurosci 123(1): 181-95.

Pike CJ, Walencewicz-Wasserman AJ, Kosmoski J, Cribbs DH, Glabe CG, Cotman

CW. 1995. Structure-activity analyses o f β-amyloid peptides: contributions of

the β 25-35 region to aggregation and neurotoxicity. J Neurochem 64: 253-265.

Page 42: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

385 References

Piluzza G, Bullitta S. 2011. Correlations between phenolic content and antioxidant

properties in twenty-four plant species of traditional ethnoveterinary use in the

Mediterranean area. Pharm Biol 49(3): 240-247.

Pitt J, Roth W, Lacor P, Blankenship M, Velasco P, Felice FD, Breslin P, Klein WL.

2009. Alzheimer‘s-associated Aβ oligomers show altered structure,

immunoreactivity and synaptotoxicity with low doses of oleocanthal. Toxicol

Appl Pharmacol 240(2): 189-197.

Plassman BL, Langa KM, Fisher GG, Heering SG, Weir DR, Ofstedal MB, Burke JR,

Hurd DD, Potter GG, Rodgers WL, Steffens DC, Willis RJ, Wallace RB. 2007.

Prevalence of Dementia in the United States: The Aging, Demographics, and

Memory Study. Neuroepidemiol 29(1-2): 125-32.

Porat Y, Abramowitz A, Gazit E. 2006. Inhibition of Amyloid Fibril Formation by

Polyphenols: Structural Similarity and Aromatic Interactions as a Common

Inhibition Mechanism. Chem Biol Drug Des 67(1): 27-37.

Povova J, Ambroz P, Bar M, Pavukova V, Sery O, Tomaskova H, Janout V. 2012.

Epidemiological Of And Risk Factors For Alzheimer‗S Disease: A Review.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 156(2): 108-14.

Prasanthi JRP, Larson T, Schommer J, Ghribi O. 2011. Silencing GADD153/CHOP

Gene Expression Protects against Alzheimer‘s Disease-Like Pathology Induced

by 27-Hydroxycholesterol in Rabbit Hippocampus. PLoS ONE 6(10): e26420.

doi:10.1371/journal.pone.0026420.

Pratico D. 2008. Evidence of oxidative stress in Alzheimer's disease brain and

antioxidant therapy: lights and shadows. Ann N Y Acad Sci 1147: 70-78.

Prediger RD, Franco JL, Pandolfo P, Medeiros R, Duarte FS, Di Giunta G, Figueiredo

CP, Farina M, Calixto JB, Takahashi RN, Dafre AL. 2007. Differential

susceptibility following beta-amyloid peptide-(1-40) administration in C57BL/6

and Swiss albino mice: evidence for a dissociation between cognitive deficits

and the glutathione system response. Behav Brain Res 27: 205-213.

Premanathan M, Arakaki R, Izumi H, Kathiresan K, Nakarno M, Yamamoto N,

Nakashima H. 1999. Antiviral properties of a mangrove plant, Rhizophora

apiculata blume, against human immunodeficiency virus. Antiviral Res 44(2):

113-122.

Premanathan M, Chandra K, Kathiresan K. 1992b. Antiviral Activity of Marine Plants

from India Antiviral Res 17(l): 154.

Puspitasar YE, Aniek HM, Eddy S. 2012. The Potency of Rhizophora mucronata Leaf

Extract as Antidiarrhea J Appl Sci Res 8(2): 1180-1185.

Page 43: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

386 References

Pytlowany M, Strosznajder JB, Jęśko H, Cąkałaand H, Strosznajder RP. 2008.

Molecular mechanism of PC12 cell death evoked by sodium nitroprusside, a

nitric oxide donor. Acta Biochi Polon 55(2): 339-347.

Qasim SZ. 1998. Mangroves.In : Glimpses of the Indian Ocean. University Press:

Hyderabad, 123‐129.

Qiu C, Backman L, Winblad B, Aguero-Torres H, Fratiglion L. 2001. The influence of

education on clinically diagnosed dementia incidence and mortality data from

the Kungsholmen Project. Arch Neurol 58: 2034-39.

Quinn JF, BussiereJR, Hammond RS, Montine TJ, Henson E, Jones RE, Stackman RW.

2007. Chronic dietary -lipoic acid reduces deficits in hippocampal memory of

aged Tg2576 mice. Neurobiol Aging 28: 213-25.

Racke MM, Boone LI, Hepburn DL, Parsadainian M, Bryan MT, Ness DK, Piroozi KS,

Jordan WH, Brown DD, Hoffman WP, Holtzman DM, Bales KR, Gitter BD,

May PC, Paul SM, DeMattos RB. 2005. Exacerbation of Cerebral Amyloid

Angiopathy-Associated Microhemorrhage in Amyloid Precursor Protein

Transgenic Mice by Immunotherapy Is Dependent on Antibody Recognition of

Deposited Forms of Amyloid. J Neurosci 25(3): 629-636.

Rahman A, Hasan SN, Sampad KS, Das AK. 2011. Antinociceptive, antidiarrhoel and

cytotoxic activities of Rhizophora mucronata Lamk. Pharmacologyonline 1:

921-929.

Raju M, Varakumar S, Lakshminarayana R, Krishnakantha TP, Baskaran V. 2007.

Carotenoid composition and vitamin A activity of medicinally important green

leafy vegetables. Food Chem 101: 1621-1628.

Ralph ET, Guest JR, Green J. 1998. Altering the anaerobic transcription factor FNR

confers a hemolytic phenotype on Escherichia coli K12. PNAS USA 95: 10449-

10452.

Ramassamy C. 2006. Emerging role of polyphenolic compounds in the treatment of

neurodegenerative diseases: a review of their intracellular targets. Eur J

Pharmacol 545: 51-64.

Ramesh BN, Indi SS, Rao KS. Anti-amyloidogenic property of leaf aqueous extract of

caesalpinia crista. Neurosci Lett 475(2): 110-114.

Ramulu P, Rao PU. 2003. Total, insoluble and soluble dietary fiber contents of Indian

fruits. J Food Comp Anal 16: 677-685.

Ran Q, Gu M, Remmen HV, Strong R, Roberts JL, Richardson A. 2006. Glutathione

peroxidase 4 protects cortical neurons from oxidative injury and amyloid

toxicity. J Neurosci Res 84(1): 202-208.

Page 44: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

387 References

Rao Y, Xiang B. 2009. Determination of total ash and acid insoluble ash of Chinese

herbal medicine Prunellae Spica by near Infrared spectroscopy. Yakaugaku

Zasshi 129(7): 881-886.

Rautera AP, Branco I, Lopes RG, Justino J, Silva FVM, Noronha JP, Cabrita EJ,

Brouard I, Bermejo J. 2007. A new lupene triterpenetriol and anticholinesterase

activity of Salvia sclareoides. Fitoterapia 78: 474-481.

Raza H, John A. 2006. 4-hydroxynonenal induces mitochondrial oxidative stress,

apoptosis and expression of glutathione S-transferase A4-4 and cytochrome

P450 2E1 in PC12 cells. Toxicol Appl Pharmacol 216(2):309-318.

Razienh Y, Hamad S. 2009. Protective effect of triazine-derivative (AA3E2) on

bamyloid-induced damage in SK-N-MC cells. Toxicol. In Vitro 23: 1277-1283.

Reichman WE. 2003. Current pharmacologic options fro patients with Alzheimer‘s

disease. Ann Gen Hosp Psychiatry 2: 1.

Reitz C. 2012. Alzheimer‘s Disease and the Amyloid Cascade Hypothesis: A Critical

Review. Int J Alzheimers Dis Article ID 369808, 11 pp.,

doi:10.1155/2012/369808.

Reuben DB, Judd-Hamilton L, Harris TB, Seeman TE. 2003. The associations between

physical activity and inflammatory markers in high-functioning older persons:

MacArthur Studies of Successful Aging. J Am Geriatr Soc 51: 1125-30.

Rhee IK, Van de Meent, M, Ingkaninan K, Verpoorte R. 2001. Screening for

acetylcholinesterase inhibitors from Amaryllidaceae using silica gel thin-layer

chromatography in combination with bioactivity staining. J Chromatogr A 915:

217-223.

Ribble D, Goldstein N, Norris D, Shellman Y. 2005. A simple technique for quantifying

apoptosis in 96 well plates. BMC Biotechnol 5:12 doi:10.1186/1472-6750-5-12.

Rice-Evans CA, Miller NJ, Bolwell PG, Bramley PM, Pridh JB. 1995. The relative

antioxidant activities of plant-derived polyphenolics flavonoids. Free Radic Res

22: 375-383.

Richard F, Amouvel P. 2001. Genetic susceptibility factors for Alzheimer‘s disease.

Eur J Pharmacol 412(1): 1-12.

Riederer P, Danielczyk W, Grünblatt E. 2004. Monoamine Oxidase-B Inhibition in

Alzheimer‘s disease. NeuroToxicology 25(1-2): 271-277.

Ritchie K, Lovestone S. 2002. The dementias. Lancet 360(9347):1759-66.

Robertson JA, De Monredon FD, Dysseler P, Guillon F, Amadò R, Thibault J. 2000.

Hydration properties of dietary fibre and resistant starch: A European

collaborative study. LWT Food Sci Technol 33(2): 72-79.

Page 45: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

388 References

Roddick JG. 1989. The acetylcholinesterase inhibitory activity of steroidal

glycoalkaloids and their aglycones. Phytochem 28: 2631-34.

Rogers J. 2008. The Inflammatory Response in Alzheimer's Disease. J Periodontol

79(8): 1535-1543.

Rohan de Silva HA, Jen A, Wickenden C, Jem LS, Wilkinson SL, Patel AJ. 1997. Cell-

specific expression of beta-amyloid precursor protein isoform mRNAs and

proteins in neurons and astrocytes. Brain Res Mol Brain Res 47(1-2): 147-156.

Rosas-Ballina M, Tracey KJ. 2009. The neurology of the immune system: Neural

reflexes regulate immunity. Neuron 64(1): 28-32.

Roses AD, Saunders AM, Huang Y, Strum J, Weisgraber KH, and Mahley RW. 2007.

Complex disease-associated pharmacogenetics: drug efficacy, drug safety, and

confirmation of a pathogenetic hypothesis (Alzheimer‘s disease).

Pharmacogenomics J 7: 10-28.

Sabo SL, Ikin AF, Buxbaum JD, Greengard P. 2001. The Alzheimer amyloid precursor

protein (APP) and FE65, an APP-binding protein, regulate cell movement. J

Cell Biol 153: 1403-1414.

Sachdev P. 1999. Vascular cognitive disorder. Int J Geriatr Psychiatry 14(5): 402-403

Saido T, Leissring MA. 2012. Proteolytic degradation of amyloid beta protein. Cold

Spring Harb Perspect Med. 2(6): a006379, doi: 10.1101/cshperspect.a006379.

Saito A, Maier CM, Narasimhan P, Nishi T, Song YS, Yu F, Liu J, Lee Y-S, Nito C,

Kamada H, Dodd RL, Hsieh LB, Hassid B, Kim EE, González M, Chan PH.

2005. Oxidative stress and neuronal death/survival signaling in cerebral

ischemia. Mol Neurobiol 31(1-3): 105-116.

Sakaguchi M, Koseki M, Wakamatsu M, Matsumura E. 2006. Effects of systemic

administration of β-casomorphin-5 on learning and memory in mice. Eur J

Pharmacol 530(1-2): 81-87.

Salomone S, Caraci F, Leggio GM, Fedotova J, Drago F. 2012. New pharmacological

strategies for treatment of Alzheimer's disease: focus on disease modifying

drugs. Br J Clin Pharmacol 73(4): 504-517.

Salo-Vaananen PP, Koivistoinen PE. 1996. Determination of protein in foods:

Comparison of net protein and crude protein (N x 6.25) values. Food Chem 57:

27-31.

Sano M, Ernesto C, Thomas RG, Klauber MR, Schafer K, Grundman M, Woodbury P,

Growdon J, Cotman CW, Pfeiffer E, Schneider LS, Thal LJ. 1997. A Controlled

Trial of Selegiline, Alpha-Tocopherol, or Both as Treatment for Alzheimer's

Disease. N Engl J Med 336(17): 1216-1222.

Page 46: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

389 References

Santoso J, Gunji S, Yoshie-Stark Y, Suzuki T. 2006a. Mineral contents of

Indonesianseaweeds and mineral solubility affected bybasic cooking. Food Sci

Technol Res 12 (1): 59-66.

Sarg TM, Abbas FA, El-Sayed ZI, Mustafa AM. 2011. Two new polyphenolic

compounds from Ficus retusa L."variegata" and the biological activity of the

different plant extracts. JPP 3(7): 89-100.

Sarker SD, Nahar L. 2012. An introduction to natural products isolation. Methods Mol

Biol 864: 1-25.

Satoh T, Enokido Y, Aoshima H, Uchiyama Y, Hatanaka H. 1997. Changes in

mitochondrial membrane potential during oxidative stress-induced apoptosis in

PC12 cells. J Neurosci Res 50: 413-442.

Savelev SU, Okello E, Perry EK. 2004. Butyryl- and acetylcholinesterase inhibitory

activities in essential oils of Salvia species and their constituents. Phytother Res

18: 315-324.

Sayre LM, Perry G, Smith MA. 2008. Oxidative stress and neurotoxicity. Chem Res

Toxicol 21: 172-188.

Scalbert A, Manach C, Morand C, Rémésy C, Jiménez L. 2005. Dietary polyphenols

and the prevention of diseases. Crit Rev Food Sci Nutr 45(4): 287-306.

Scarmeas N, Luchsinger JA, Schupf N, Brickman AM, Cosentino S, Tang MX, Stern

Y. 2009. Physical activity, diet, and risk of Alzheimer disease. JAMA 302: 627 -

37.

Scarpini E, Scheltens P, Feldman H. 2003. Treatment of Alzheimer‘s disease: current

status and new perspectives. Lancet 2: 539-547.

Scheff SW, Price DA, Schmitt FA, DeKosky ST, Mufson EJ. 2007. Synaptic alterations

in CA1 in mild Alzheimer disease and mild cognitive impairment. Neurology

68: 1501-1508.

Schjeide BM, Schnack C, Lambert JC, Lill CM, Kirchheiner J, Tumani H, Otto M,

Tanzi RE, Lehrach H, Amouyel P, von Arnim CA, Bertram L. 2011. The role of

clusterin, complement receptor 1, and phosphatidylinositol binding clathrin

assembly protein in Alzheimer disease risk and cerebrospinal fluid biomarker

levels. Arch Gen Psychiatry 68(2): 207-213.

Schliebs R, Arendt T. 2011. The cholinergic system in aging and neuronal

degeneration. Behav Brain Res 221: 555-563.

Schram E, Gillari J. 2012. From cellular senescence to age-associated diseases: the

miRNA connection. Longevity and Health span 1:10.

Page 47: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

390 References

Schrijvers EM, Koudstaal PJ, Hofman A, Breteler MM. 2011. Plasma clusterin and the

risk of Alzheimer disease. JAMA 305: 1322-26.

Seabrook TJ, Jiang L, Maier M, Lemer CA. 2006. Minocycline affects microglia

activation, Aβ deposition, and behavior in APP-tg mice. Glia 53(7): 776-782.

Sedlak J, Lindsay RH. 1968. Estimation of total, protein-bound and nonprotein

sulfhydryl groups in tissue with Ellman's reagent. Anal Biochem 25: 192-205.

Selkoe DJ, Schenk D. 2003. Alzheimer's disease: molecular understanding predicts

amyloid-based therapeutics. Annu Rev Pharmacol Toxicol 43: 545-584.

Selkoe DJ. 2001. Clearing the brain‘s amyloid cobwebs. Neuron 32: 177-180.

Selvam V. 2003. Environmental classification of mangrove wetlands of India. Curr Sci

84(6): 757-765.

Sepcic K. 2000. Bioactive alkylpyridinium compounds from marine sponges. J Toxicol

Toxin Rev 19: 139-60.

Serrano-Pozo A, Frosch Mp, Masliah E, Hyman BT. 2012. Neuropathological

Alterations in Alzheimer Disease. Cold Spring Harb Perspect Med 1: ea006189

Shad MA, Nawaz HAQ, Hussain M, Yousuf B. (2011). Proximate composition and

functional properties of Rhizomes of lotus (Nelumbo nucifera) from Punjab.

Pak J Bot 43(2): 895-904.

Shaji KS. 2009. Dementia care in developing countries: The road ahead. Indian J

Psychiatry 51(5): 5-7.

Shankar GM, Walsh DM. 2009. Alzheimer's disease: synaptic dysfunction and Aβ. Mol

Neurodegener 4: 48

Shearman MS, Ragan CI, Iversen LL. 1994. Inhibition of PC 12 cell redox activity is

specific, early indicator of the mechanism of -amyloid-mediated cell death.

Proc Natl Acad Sci USA 91: 1470e4.

Sherrington R, Rogaev EI, Liang Y, Rogaeva EA, Levesque G, Ikeda M, Chin H, Lin

C, Li G, Holman K, Tsuda T, Mar L, Foncin JF, Bruni AC, Montesi MP, Sorbi

S, Rainero I, Pinessi L, Nee L, Chumakov I, Pollen D, Brookes A, Sanseau P,

Polinsky RJ, Wasco W, Da silva HA, Haines JL, Perkicak-Vance MA Tanzi

RE,Roses AD, Fraser PE, Rommens JM, St George-Hyslop PH. 1995. Cloning

of a gene bearing missense mutations in early-onset familial Alzheimer's

disease. Nature 375(6534): 754-60.

Shinwari ZK, Rehman M, Watanabe T, Yoshikawa Y. 2006. Medicinal and Aromatic

Plants of Pakistan (A Pictorial Guide). Kohat University of Science and

Technology, Kohat: Pakistan, 492 pp.

Page 48: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

391 References

Shivaprasad HN, Mohan S, Kharya MD, Shiradkar RM, Lakshman K. 2005. Invitro

models for antioxidant activity evaluation: A review. Latest rev 3(4).

Singh G, Kawatra A, Shegal S. 2001. Nutritional composition of selected green leafy

vegetables, herbs and carrots. Plant Food Hum Nutr 56: 359-364.

Singh KB, Taneja SK. 2010. Effect of Long Term Excessive Zn Supplementation on

Blood Lipid Profile and Tissue Minerals Status in Wistar Rat. J Exp Sci 1(3): 4-

9.

Singh N, Verma P, Pandey BR. 2012. Therapeutic Potential of Organic Triticum

aestivum Linn. (Wheat Grass) in Prevention and Treatment of Chronic Diseases:

An Overview. Int J Pharma Sci Drug Res 4(1): 10-14.

Singh VP. 2002. Mangrove biodiversity, causes of loss and conservation and

management approach. Mangrove Conservation and Restoration, MSSRF,

Chennai.

Singleton VL, Rossi JA. 1965. Colorimetry of total phenolics with phosphomolybdic-

phosphotungstic acid reagents. Am J Enol Vitic 16: 144-158.

Sivam AS, Sun-Waterhouse D, Quek SY, Perera CO. 2010. Properties of Bread Dough

with Added Fiber Polysaccharides and Phenolic Antioxidants: A Review. J

Food Sci 75(8): 163-174.

Sivaraman D, Muralidharan P, Panneerselvam P. 2012. Ameliorating Effect of Ethanol

Leaf Extract of Ficus hispida Linn. on Amyloid beta Aβ (25-35) Induced

Cognitive Deficits and Oxidative Stress in Alzheimer‘s Mice. Int J Pharmacol

8: 212-223.

Skoumalová A, Ivica J, Santorova P, Topinkova E, Wilhelm J. (2011). The lipid

peroxidation products as possible markers of Alzheimer's disease in blood. Exp

Gerontol 46 (1): 38-42.

Skovronsky DM, Lee VM, Trojanowski JQ. 2006. Neurodegenerative diseases: new

concepts of pathogenesis and their therapeutic implications. Annu Rev Pathol

1:151-170.

Skovronsky DM, Zhang B, Kung M-P, Kung HF, Trojanowski JQ, Lee VM. 2000. In

vivo detection of amyloid plaques in a mouse model of Alzheimer‘s disease.

Proc Natl Acad Sci USA 97:7609-7614.

Slater TF. 1988. Lipid Peroxidation and Cell Division in Normal and Tumour Tissues.

Eicosanoids Lipid Peroxidation Cancer 137-142.

Small DH, Clarris HL, Williamson TG, Reed G, Key B, Mok SS, Beyreuther K,

Masters CL, Nurcombe V. 1999. Neurite-outgrowth regulating functions of the

amyloid protein precursor of Alzheimer's disease. J Alzheimers Dis 1: 275-285.

Page 49: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

392 References

Smith AR, Shenvi SV, Widlansky M, Suh JH, Hagen TM. 2004. Lipoic acid as a

potential therapy for chronic diseases associated with oxidative stress. Curr Med

Chem 11: 1135-1146.

Smith F, Green KN, LaFerla FM. 2005. Calcium dysregulation in Alzheimer‘s disease:

recent advances gained from genetically modified animals. Cell Calcium 38(3-

4): 427-437.

Sonkusare SK, Kaul CL, Ramarao P. 2005. Dementia of Alzheimer‘s disease and other

neurodegenerative disorders—memantine, a new hope. Pharmacol Res 51: 1-

17.

Sparks DL, Connor DJ, Sabbagh MN, Petersen RB, Lopez J, Browne P. 2006.

Circulating cholesterol levels, apolipoprotein E genotype and dementia severity

influence the benefit of atorvastatin treatment in Alzheimer's disease: results of

the Alzheimer's Disease Cholesterol-Lowering Treatment (ADCLT) trial. Acta

Neurologica Scandinavica 114(185): 3-7.

Srikanth J, Muralidharan P. 2010. Evaluation of Antioxidant Properties of Sapindus

emarginatus Vahl. Asian J Exp Biol Sci 1(3): 693-99.

Srikumar T. 1993. The mineral and trace element composition of vegetables, pulses and

cereals of southern India. Food Chem 46:163-167.

Srivastava R. 2011. Nurtitional quality of some cultivated and wild species of

Amranthus L. IJPSR 2(12): 3152-3156.

Stewart R. 2002. Vascular dementia: a diagnosis running out of time. BJP 180: 152-56.

Stockley JH, Ravid R, O‘Neill C. 2006. Altered beta-secretase enzyme kinetics and

levels of both BACE1 and BACE2 in the Alzheimer's disease brain. FEBS Lett

580: 6550-6560.

Street RA, Stirk WA, Van Staden J. 2008. South African traditional medicinal plant

trade - challenges in regulating quality, safety and efficacy. J Ethnopharmacol

119: 705-710.

Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen

GS, Roses AD (1993). Apolipoprotein E: high-avidity binding to beta-amyloid

and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

Proc Natl Acad Sci USA 90: 1977-1981.

Strobel G, 2008b. Chicago: Bapineuzumab's Phase 2—was the data better than the

spin? Available online at http://www.alzforum.org/new/detail.asp?id=189.

Subramoniam A, Asha VV, Nair SA, Sasidharan SP, SureshKumar PK, Rajendran KN,

Karunagaran D, Ramalingam K. 2012. Chlorophyll revisited: anti-inflammatory

Page 50: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

393 References

activities of chlorophyll A and inhibition of expression of TNF- gene by the

same. Inflammation 35(3): 959-966.

Suganthy N, Kesika P, Pandian SK, Devi KP. 2009. Mangrove Plants Extract: Radical

Scavenging Activities and Its Battle against Food Borne Pathogens. Forsch

Komplementmed 16: 41-48.

Suganthy N, Pandian SK, Devi KP. 2013. Plants traditionally used in age-related brain

disorders (dementia): an ethanopharmacological survey. Pharm Biol 51(4): 492-

523

Suganthy N, Pandian SK, Devi KP. 2009. Cholinesterase inhibitory effects of

Rhizophora lamarckii, Avicennia officinalis, Sesuvium portulacastrum and

Suevada monica: Mangroves inhabiting Indian coastal area (Vellar Estuary). J

Enz Inhib Med Chem 24(3): 702-707.

Sugimoto H, Yamanishi Y, Iimura Y, Kawakam Y. 2000. Donepezil Hydrochloride

(E2020) and Other Acetylcholinesterase Inhibitors. Curr Med Chem 7: 303-

339.

Suh SJ, Koo BS, Jin UH, Hwang MJ, Lee IS, Kim CH. 2006. Pharmacological

characterization of orally active cholinesterase inhibitory activity of Prunus

persica L. Batsch in rats. J Mol Neurosci 29: 101-107.

Suk K, Lee H, Kang SS, Cho GJ, Choi WS. 2003. Flavonoid Baicalein Attenuates

Activation-Induced Cell Death of Brain Microglia. JPET 305: 638-645.

Sul D, Kim HS, Cho EK, Lee M, Kim HS, Jung WW, Hwang KW, Park SY. 2009.

2,3,7,8-TCDD neurotoxicity inneuroblastoma cells is caused by increased

oxidative stress, intracellular calcium level and tau phosphorlyation. Toxicology

255(1-2): 65-71.

Sultana RD, Butterfield A. 2009. Oxidatively modified, mitochondria-relevant brain

proteins in subjects with Alzheimer disease and mild cognitive impairment. J

Bioenerg Biomembr 41(5): 441-446.

Sung SH, Kang SY, Lee KY, Park MJ, Kim JH, Park JH, Kim YC, Kim J, Kim YC.

2002. (+)-aViniferin, a stilbene trimer from Caragana chamlague inhibits

acetylcholinesterase. Biol Pharm Bull 25: 125-127.

Suzuki T, Ohsugi Y, Yoshie Y, Shirai T, Hirano T. 1996. Dietary fiber content, water

holding capacity and binding capacity of seaweeds. Fisheries Sci 62: 454-461.

Swamy SMK, Tan BKH. 2000. Cytotoxic and immunopotentiating effects of ethanolic

extract of Nigella sativa L. seeds. J Ethnopharmacol 70: 1-7.

Szwajgier D, Borowiec K. 2012. Phenolic acids from malt are efficient acetyl

cholinesterase and butyrylcholinesterase inhibitors. J Inst Brew 118(1): 40-48.

Page 51: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

394 References

Takasugi N, Tomita T, Hayashi I, Tsuruoka M, Niimura M, Takahashi Y, Thinakaran

G, Iwatsubo T. 2003. The role of presenilin cofactors in the -secretase complex.

Nature 422: 438-441.

Takuma H, Tomiyama T, Kuida K, Mori H. 2004. Amyloid beta peptide-induced

cerebral neuronal loss is mediated by caspase-3 in vivo. J Neuropathol Exp

Neurol 63(3): 255-261.

Takuma K, Yan SS, Stern DM, Yamda K. 2005. Mitochondrial Dysfunction,

Endoplasmic Reticulum Stress, and Apoptosisin Alzheimer‘s Disease. J

Pharmacol Sci 97: 312-316.

Tamagno E, Guglielmotto M, Aragno M, Borghi R, Autelli R, Giliberto L, Muraca G,

Danni O, Zhu X, Smith M, Perry G, Jo D, Mattson M, Tabaton M. 2008.

Oxidative stress activates a positive feedback between the gamma- and beta-

secretase cleavages of the beta-amyloid precursor protein. J Neurochem 10:

683-695

Tamagno E, Guglielmotto M, Mon Tamagno E, Guglielmotto M, Monteleone D,

Vercelli A, Tabaton M. 2012. Transcriptional and post-transcriptional regulation

of β-secretase. IUBMB Life 64: 943-50.

Tanaka K, Hayatsu T, Negishi T, Hayatsu H. 1998. Inhibition of N-nitrosation of

secondary amines in vitro by tea extracts and catechins. Mutat Res 412: 91-98.

Tanaka S, Shiojiri S, Takahashi Y, Kitaguchi N, Ito H, Kameyama M, Kimura J,

Nakamura S, Uead K. 1989. Tissue expression of three types of b-protein

precursor mRNA: enhancement of protease inhibitor-harboring types in

Alzheimer‘s disease brain. Biochem Biophys Res Commun 165: 1406–1414

Tanaka T, Shnimizu M, Moriwaki H. 2012. Cancer Chemoprevention by Carotenoids.

Molecules 17: 3202-3242.

Taniguchi S, Suzuki N, Masuda M, Hisanaga S, Iwatsubo T, Goedert M, Hasegawa M.

2005. Inhibition of heparin induced tau filament formation by phenothiazines,

polyphenols, and porphyrins. J Biol Chem 280: 7614-7623.

Tanzi RE 2012. The genetics of Alzheimer disease. Cold Spring Harb Perspect Med 2:

a006296

Teipel SJ, Flatz WH, Heinsen H, Bokde AL, Schoenberg SO, Stockel S, Dietrich O,

Reiser MF, Moller HJ, Hampel H. 2005. Measurement of basal forebrain

atrophy in Alzheimer‘s disease using MRI. Brain 128: 2626-44.

Teo S, Stirling D, Thomas S, Hoberman A, Kiorpes A, Khetani V. 2002. A 90 day oral

gavage toxicity studies of D methyl penidate and DL methyl penidate in

Sprague Dawley rats. Toxicology 179: 183-196

Page 52: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

395 References

Thakur NL, Thakur AN, Muller WEG. 2005. Marine natural products in drug

discovery. NPR 4(6): 471-477.

Thal DR, Ru¨b U, Orantes M, Braak H. 2002. Phases of Ab-deposition in the human

brain and its relevance for the development of AD. Neurology 58: 1791-1800.

The Organization of Economic Co-operation Development (OECD), 1997a. The OECD

Guideline for Testing of Chemical: 476 in vitro mammalian cell gene mutation

test. OECD: Paris; 1-10.

The Organization of Economic Co-operation Development (OECD), 2001b. The OECD

Guideline for Testing of Chemical: 420 Acute Oral Toxicity. OECD: Paris; 1-

14.

The Organization of Economic Co-operation Development (OECD), 2001a. The OECD

Guideline for Testing of Chemical: 407 Repeated Dose Oral Toxicity-Rodent:

28-Day or 14-Day Study. OECD: Paris; 1-7.

Thirugnanasampandan R, Jayakumar R, Narmatha Bai V, Martin E, Rajendra Prasad

KJ. 2008. Antiacetylcholinesterase and antioxidant Kaurene diterpenoid

melissoides from Isodon wightii. Nat Prod Res 22: 681-688.

Thomas T. 2000. Monoamine oxidase-B inhibitors in the treatment of Alzheimer's

disease. Neurobiol Aging 21(2): 343-348.

Thunus L, Lejeune R. 1994. Handbook on Metals in Clinical and Analytical Chemistry.

Marcel Dekker: New York, USA.

Tice RR, Agurell E, Anderson D, Burlinson B, Hartmann A, Kobayashin H, Miyamae

Y, Rojas E, Ryu JC, Sasaki YF. 2000. Single Cell Gel/Comet Assay: Guidelines

for In Vitro and In Vivo Genetic Toxicology Testing. Environ Mol Mutagen 35:

206-221.

Togo T, Katsuse O, Iseki E. 2004. Nitric oxide pathways in Alzheimer's disease and

other neurodegenerative dementias. Neurol Res 26(5): 563-566.

Tohda C, Tamura T, Matsuyama S, Komatsu K. 2006. Promotion of axonal maturation

and prevention of memory loss in mice by extracts of Astragalus mongholicus.

Br J Pharmacol 149: 532-541.

Tomimoto H, Akiguchi I, Wakita H, Nakamura S, Kimura J. 1995. Ultrastructural

localization of amyloid protein precursor in the normal and postischemic gerbil

brain. Brain Res 672(1-2): 187-195.

Traber MG, van dV, Reznick AZ, Cross CE. 2000. Tobacco related diseases. Is there a

role for antioxidant micronutrient supplementation? Clin Chest Med 21: 173.

Page 53: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

396 References

Trinh NH, Hoblyn J, Mohanty S, Yaffe K. 2003. Efficacy of cholinesterase inhibitors in

the treatment of neuropsychiatric symptoms and functional impairment in

Alzheimer disease. JAMA 289(2): 210-216.

Tsai SH, Lin-Shiau SY, Lin JK. 1999. Suppression of nitric oxide synthase and the

down regulation of the activation of NF-κB in macrophages by resveratrol. Brit

J Pharmacol 126: 673-680.

Tsunekawa N, Noda Y, Mouri A, Yoneda F, Nabeshima T. 2008. Synergistic effects of

selegiline and donepezil on cognitive impairment induced by amyloid beta (25-

35). Behav Brain Res 190(2): 224-232.

Tuntipopipat S, Muangnoi C, Chingsuwanrote P. 2011. Anti-inflammatory activities of

red curry paste extract on lipopolysaccharide-activated murine macrophage cell

line. Nutrition 27(4): 479-487.

Turner ND, Lupton JR. 2011. Dietary fiber. Adv Nutr 2:151-152.

Turner PR, O‘Connor K, Tate WP, Abraham WC. 2003. Roles of amyloid precursor

protein and its fragments in regulating neural activity, plasticity and memory.

Prog Neurobiol 70(1):1-32.

Tuszynski MH. 2007. Nerve growth factor gene delivery: animal models to clinical

trials. Dev Neurobiol 67(9): 1204-1215.

Um MY, Choi W-H, Aan J-Y, Kim S-R, Ha T-Y. 2006. Protective effect of Polygonum

multiflorum Thunb on amyloid β-peptide 25-35 induced cognitive deficits in

mice J Ethnopharmacol 104: 144-148.

Umamaheswari M, Chatterjee TK. 2008. In vitro antioxidant activities of the fractions

of Coccinia Grandis L. leaf extract. Afr J Trad Comp Alter Med 5: 61-73.

Urbain A, Marston A, Queiroz EF, Ndjoko K, Hostettmann K. 2004. Xanthones from

Gentiana campestris as new acetylcholinesterase inhibitors. Planta Med 70:

1011-14.

Uto T, Qin GW, Morinaga O, Shoyama Y. 2012. 17-Hydroxy-jolkinolide B, a

diterpenoid from Euphorbia fischeriana, inhibits inflammatory mediators but

activates heme oxygenase-1 expression in lipopolysaccharide-stimulated murine

macrophages. Int Immunopharmacol 12(1): 101-109.

Valencia E, Martin A, Hardy G. 2001. Glutathione - nutritional and pharmacologic

viewpoints. Nutrition, 17: 783-784.

van der Flier WM, Scheltens P. 2005. Epidemology and risk factors of dementia. J

Neurol Neurosurg Psychiatry 76(5): 2-7.

Page 54: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

397 References

van Gelder BM, Tijhuis M, Kalmijn S, Kromhout D. 2007. Fish consumption, n-3 fatty

acids, and subsequent 5-y cognitive decline in elderly men: The Zutphen Elderly

Study. Am J Clin Nutr 85: 1142-47.

Vauzour D. 2012. Dietary Polyphenols as Modulators of Brain Functions:Biological

Actions and MolecularMechanisms UnderpinningTheir Beneficial Effects. Oxid

Med Cell Longev Article ID 914273, 16 pp., doi:10.1155/2012/914273.

Vina J, Comez-Cabrera MC, Borras C. 2007. Fostering antioxidant defences:

upregulation of antioxidant genes or antioxidant supplement? Br J Nutr 98: S3-

S40.

Vilatela MEA, Lopez ML, Gomez PY. 2012. Genetics of Alzheimer‘s disease. Arch

Med Res 43(8): 622-631.

Villano D, Fernandez-Pachon MS, Moya ML, Troncoso AM and Garcia-Parrilla MC.

2007. Radical scavenging ability of polyphenolic compounds towards DPPH

free radical. Talanta 71(1): 230-235.

Villard V, Espallergues J, Keller E, Alkam T, Nitta A, Yamada K, Nabeshima T,

Vamvakides A, Maurice T. 2008. Antiamnesic and Neuroprotective Effects of

the Aminotetrahydrofuran Derivative ANAVEX1-41 Against Amyloid β 25-35-

Induced Toxicity in Mice Neuropsychopharmacology 34: 1552-1566.

Vinutha B, Prashanth D, Salma K, Sreeja SL, Pratiti D, Padmaja R, Radhika S, Amita

A, Venkateshwarlu K, Deepak M. 2007 Screening of selected Indian medicinal

plants for acetylcholinesterase inhibitory activity. J Ethnopharmacol 109: 359-

63.

Vorarat S, Managit C, Iamthanakul L, Soparat W, Kamkaen N. 2010. Examination of

antioxidant activity and development of rice bran oil and gamma-oryzanol

microemulsion. J Health Res 24(2): 67-72.

Votyakova TV, Reynolds IJ. 2001. ΔΨm-Dependent and -independent production of

reactive oxygen species by rat brain mitochondria. J Neurochem 79 (2): 2, 266-

277.

Wagner H, Bladt S, Zgainski EM. 1984. Plant Drug Analysis. SpringerVerlag: New

York, 163-172.

Walsh GE. 1977. Explotation of mangal In: Ecosystem of the world: wet coastal

ecosystem. chapman VJ(ed.). Elsevier Science publishing company:

Amsterdam.

Wang H, Xu H, Dyck LE, Li XM. 2005. Olanzapine and Quetiapine Protect PC12 Cells

From -Amyloid Peptide 25-35- Induced Oxidative Stress and the Ensuing

Apoptosis. J Neurosci Res 81:572-580.

Page 55: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

398 References

Wang M, Kikizaki H, Zhu N, Sang S, Nakatani N, Ho CT. 2000. Isolation and

structural elucidation of two new glycosides from sage (Salvia officinalis). J

Agric Food Chem 48: 235-238.

Wang Q, Rowan MJ, Anwyl R. 2004. Beta-amyloid-mediated inhibition of NMDA

receptor-dependent long-term potentiation induction involves activation of

microglia and stimulation of inducible nitric oxide synthase and superoxide. J

Neurosci 24: 6049-6056.

Wang W-N, Zhou J, Wang P, Tian T-T, Zheng Y, Liu Y, Mai W-J, Wang A-L. 2006.

Oxidative stress, DNA damage and antioxidant enzyme gene expression in the

Pacific white shrimp, Litopenaeus vannamei when exposed to acute pH stress.

Comp Biochem Physiol Part C: Toxicol Pharmacol 150(4): 428-435.

Wang Y, Ha Y. 2004. The X-ray structure of an antiparallel dimer of the human

amyloid precursor protein E2 domain. Mol Cell 15: 343-353.

Wang YH, Du GH. 2009. Ginsenoside Rg1 inhibits beta-secretase activity in vitro and

protects against Abeta-induced cytotoxicity in PC12 cells. J Asian Nat Prod Res

11(7): 604-612.

Watt JM, Breyer-Brandwijk MG. 1962. The medicinal and poisonous plants of southern

and eastern Africa. 2nd

(ed.), E.&S. Livingstone, Ltd.: Edinburgh, London.

Weinreb O, Mandel S, Bar-Am O, Amit T. 2011. Iron-chelating backbone coupled

with monoamine oxidase inhibitory moiety as novel pluripotential therapeutic

agents for Alzheimer‘s disease: a tribute to Moussa Youdim. J Neural Transm

118(3): 479-492.

Wen Y, Yu WH, Maloney B, Bailey J, Ma J, Marie I, Maurin T, Wnag L, Figueroa H,

Herman M, Krishnamurthy P, Liu L, Planel E, Lau LF, Lahiri DK, Duff K.

2008. Transcriptional regulation of β-secretase by p25/cdk5 leads to enhanced

amyloidogenic processing. Neuron 57(5): 680-90.

Whitehouse PJ, Martino AM, Wagster MV, Price DL,Mayeux R, Atack JR, Kellar KJ.

1988. Reductions in 3H nicotinic acetylcholine binding in Alzheimer‘s disease

and Parkinson‘s disease: An autoradiographic study. Neurology 38: 720 -23.

Whitmer RA, Gunderson EP, Barrett-Connor E, Quesenberry CP Jr, Yaffe K. 2005a.

Obesity in middle age and future risk of dementia: A 27 year longitudinal

population based study. BMJ 330: 1360.

WHO and ADI (2012). Dementia: a public health priority. 8: 112 pp., ISBN: 978 92 4

156445.

WHO. 2007. WHO guidelines on good manufacturing practice (GMP) for herbal

medicines, Geneva.

Page 56: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

399 References

WHO. 2012. Global health and aging. World health organization report.

Wijtmans M, Leurs R, De Esch I. 2007. Histamine H3 receptor ligands break ground in

a remarkable plethora of therapeutic areas. Expert Opin Investig Drugs 16: 967-

985.

Winblad B, Poritis N. 1999. Memantine in severe dementia: Results of the sup-9M-Best

study (benefit and efficacy in severely demented patients during treatment with

memantine). J Geriatr Psych 14: 135-146.

Wolever TMS. 1990. Dietary fibre in the managementof diabetes. In: Dietary fiber.

Krischevky DB, Bonfied C, Anderson JW (eds.), Plenum press: New York; 283-

285.

Wolfe MS. 2002. Therapeutic strategies for Alzheimer's disease. Nat Rev Drug Discov

1: 859-866.

Wong GT, Manfra D, Poulet FM, Zhang Q, Josien H, Bara T, Engstrom L, Pinzon-

Ortiz M, Fine JS, Lee HJ, Zhang L, Higgins GA, Parker EM. 2004. Chronic

treatment with the gamma-secretase inhibitor LY-411,575 inhibits beta-amyloid

peptide production and alters lymphopoiesis and intestinal cell differentiation. J

Biol Chem 279(13): 12876-12882.

www.healthalternatives 2000.com.

Xian Y-F, Lin Z-X, Mao Q-Q, Hu Z, Zhao M, Che C-T, Ip S-P. 2012. Bioassay-Guided

Isolation of Neuroprotective Compounds from Uncaria rhynchophylla against

Beta-Amyloid-Induced Neurotoxicity. Evid Based Complement Alternat Med

Article ID 802625, 8 pages doi:10.1155/2012/802625.

Xie S, Wu H, Wang Q, Cogswell JP, Husain I, Conn C, Stambrook P, Jhanwar-Uniyal

M, Dai W. 2001. Plk3 functionally links DNA damage to cell cycle arrest and

apoptosis at least in part via the p53 pathway. J Biol Chem 276(46): 43305-

44312.

Xue Y, Wang Y, Feng DC, Xiao BG, Xu, LY. 2008. Tetrandrine suppresses

lipopolysaccharide induced microglial activation by inhibiting NF-kappaB

pathway. Acta Pharmacol Sin 29: 245-251.

Yaffe K, Lindquist K, Penninx BW, Simonsick EM, Pahor M, Kritchevsky S, Launer L,

Kuller L, Rubin S, Harris T. 2003. Inflammatory markers and cognition in well-

functioning African-American and white elders. Neurology 61: 76-80.

Yagi K, Rastogi R. 1979. Assay for lipid peroxides in animal tissues thiobarbituric acid

reaction. Anal Biochem 95: 351-358.

Page 57: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

400 References

Yan JJ, Cho JY, Kim HS, Kim KL, Jung JS, Huh SO, Suh HW, Kim YH, Song DK.

2001. Protection against β-amyloid peptide toxicity invivo with long-term

administration of ferulic acid. Brit J Pharmacol 133: 89-96.

Yang S, Wang S, Zhao M, Zhang R, Zhou W, Li Y, Su Y, Zhang H, Yu H. Liu R.

2012. A Peptide Binding to the -Site of APP Improves Spatial Memory and

Attenuates A Burden in Alzheimer‘s Disease Transgenic Mice. PLoS one

7(11): e48540.

Yang S, Zhang X, Sun X, Ling T, Feng Y, Du X, Zhao M, Yang Y, Xue D, Wang L,

Liu R. 2010. Diverse Ecdysterones Show Different Effects on Amyloid-β42

Aggregation but All Uniformly Inhibit Amyloid-β42-Induced Cytotoxicity. J

Alzheimers Dis 22(1): 107-117.

Yao Q, Seol D, Mi Z, Robbins PD. 2006. Intra-articular injection of recombinant

TRAIL induces synovial apoptosis and reduces inflammation in a rabbit knee

model of arthritis. Arthritis Res Ther 8: R16.

Yayli N, Kiran Z, Seymen H. Genc H. 2001. Characterisation of lipids and fatty acid

methyl ester contents in leaves and roots fo crocus vallicola. Turk J Chem 25:

391-395.

Yin KJ, Lee JM, Chen SD, Xu J, Hsu CY. 2002. Amyloid- Induces Smac Release via

AP-1/Bim Activation in Cerebral Endothelial Cells. J Neurosci 22(22): 9764-

9770.

Yoo K, Park S. 2012. Terpenoids as Potential Anti-Alzheimer‘s Disease Therapeutics.

Molecules 17: 3524-3538.

Youdim MBH, Buccafusco JJ. 2005. CNS Targets for multi-functional drugs in the

treatment of Alzheimer's and Parkinson's diseases. J Neural Transm 112: 519-

537.

Zarotsky V, Sramek JJ, Cutler NR. 2003. Galanthamine hydrobromide: an agent for

Alzheimer‘s disease. Am J Health Syst Pharm 60: 446-452.

Zhang H-Y, Liu Y-H, Wang H-Q, Xu J-H, Hu H-T. 2008. Puerarin protects PC12 cells

against β-amyloid-induced cell injury. Cell Biol Inter 32(10): 1230-1237.

Inestrosa NC. 2007. Wnt-7 Induces Presynaptic Colocalization of7-Nicotinic

Acetylcholine Receptors and Adenomatous Polyposis Coli in Hippocampal

Neurons. J Neurosci 27(20): 5313-5325.

Zhang HY, Yan H, Tang XC. 2008. Non-cholinergic effects of huperzine a: beyond

inhibition of acetylcholinesterase. Cell Mol Neurobiol 28: 173-183.

Page 58: References - Information and Library Network Centreshodhganga.inflibnet.ac.in/bitstream/10603/56668/14/14_references.pdfBarik A, Mishra B, Kunwar A, Kadam RM, Shen L, Dutta S, Padhye

401 References

Zhang L, Jope RS. 1999. Oxidative stress differentially modulates phosphorylation of

ERK, p38 and CREB induced by NGF or EGF in PC12 cells. Neurobiol Aging

20: 271e8.

Zhang Y, Thompson R, Zhang H, Xu H. 2011. APP processing in Alzheimer‘s disease.

Mol Brain 4: 3

Zhang Z, Nadeau P, Song W, Donoviel D, Yuan M, Bernstein A, Yankner BA. 2000.

Presenilins are required for γ-secretase cleavage of β-APP and transmembrane

cleavage of Notch-1. Nat Cell Biol 2: 463-465.

Zhao Z, Wang Z, Gu Y, Feil R, Hofmann F, Ma L. 2009. Regulate axon branching by

the cyclic GMP pathway via inhibition of glycogen synthase kinase 3 in dorsal

root ganglion sensory neurons. J Neurosci 29: 1350-1360.

Zhi-Kun S, Hong-Qi Y, Zhi-Quan W, Jing P, Zhen H, Sheng-Di C. 2012.

Erythropoietin prevents PC12 cells from betaamyloid-induced apoptosis via

PI3K⁄Akt pathway. Transl Neurodegener 1:7.

Zhou FM, Wilson CJ, and Dani JA. 2003 Muscarinic and nicotinic cholinergic

mechanisms in the mesostriatal dopamine systems. Neuroscientist 9: 23-36.

Zhou Y, Zhao ZQ, Xie JX. 2001. Effects of isatin on rotational behavior and DA levels

in caudate putamen in Parkinsonian rats. Brain Res 917(1): 127-132.

Zhu Y, Bickford PC, Sanberg P, Giunta B, Tan J. 2008. Blueberry opposes beta-

amyloid peptide induced microglial activation via inhibition of p44/42 mitogen-

activation protein kinase. Rejuvenation Res 11(5): 891-901.

Zhu Z, Li C, Wang X, Yang Z, Chen J, Hu L, Jiang H, Shen X. 2010. 2,2‘,4‘

trihydroxychalcone from Glycyrrhiza glabra as a new specific BACE1 inhibitor

efficiently ameliorates memory impairment in mice. J Neurochem 114(2): 374-

385.

Zivkovic S, Boada M, López O. 2000. Review of Creutzfeldt - Jakob disease and other

prion disease. Rev Neurol 31(12): 1171-1179.

Zotova E, Nicoll JAR, Kalaria R, Holmes C, Boche D. 2010. Inflammation in

Alzheimer‘s disease: relevance to pathogenesis and therapy. Alzheimer’s Res

Ther 2: 1.