rbc
TRANSCRIPT
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
About this lectureAbout this lecture
• Composition of Blood
• Plasma make up and roles
• Various cell types, origin and roles
• Red blood cells, hemoglobin & iron metabolism
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Blood Components: Plasma Transports SolutesBlood Components: Plasma Transports Solutes
• Water, ions, trace elements
• Gasses: O2 & CO2
• Organic Molecules
• Glucose
• N–wastes
• Proteins
• Antibodies
• Hormones
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Blood Components: Plasma Transports SolutesBlood Components: Plasma Transports Solutes
Figure 16-1: Composition of blood
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Blood Components: "Blood Count" – % of Each ComponentBlood Components: "Blood Count" – % of Each Component
Figure 16-2: The blood count
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Blood Components: CellsBlood Components: Cells
• Erythrocytes
• Red Blood Cells (RBC)
• O2 & CO2 transport
• White Blood Cells (WBC)
• Immune defense
• Phagocytosis
• Platelets: clotting
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Hematopoiesis: Blood Cell FormationHematopoiesis: Blood Cell Formation
• Mostly in bone marrow from stem cells
• Rate regulated by cytokines & growth factors
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Hematopoiesis: Blood Cell FormationHematopoiesis: Blood Cell Formation
Figure 16-3: Hematopoiesis
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Focus on RBCs:Focus on RBCs:
Figure 16-5c: Bone marrow
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Focus on RBCs:Focus on RBCs:
Figure 16-7a, b: Bone marrow
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Iron Metabolism: Key to Hemoglobin O2 TransportIron Metabolism: Key to Hemoglobin O2 Transport
Figure 16-8: Iron metabolism
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Some Diseases of RBCs and O2 TransportSome Diseases of RBCs and O2 Transport
Table 16-3: Causes of Anemia