publications radianc inspiring thoughts.. · palak patel, krupali parmar, vivek k. vyas, dhaval...
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Volume 11| Issue 2 | October 2017- February 2018
Institute of Pharmacy, Nirma University
RadianceInspiring Thoughts...
Chairperson
Prof. Manjunath D. Ghate
Editor
Dr. Shital Butani
Editorial Members
Dr. Renuka Mishra
Dr. Shraddha Bhadada
EDITORIAL BOARD
Student Research 09
Students’ Corner 12
Faculty Corner 14
Publications 16
Glimpses 01
From the Editor's desk 02
Dignitaries 03
Expert Lectures 05
Events 06
INSIDE....FORTHCOMING EVENTS•
• B.Pharm Poster Competition April 17, 2018
• Short term training programme (STTP) June 30, 2018 to July 14, 2018
Euphoria (Talent Hunt ) March 20, 2018
16
Institute of Pharmacy, Nirma University.
Website: http://www.nirmauni.ac.in/IPNU NirmaUniPharma
PUBLICATIONS List of Publications in reputed journals with impact
factor greater than 1:
Anna Pratima G. Nikalje, Shailee V. Tiwari, Jaydeep G. Tupe,
Vivek K. Vyas, Gulamnizami Qureshi. Ultrasound Assisted-
synthesis and Biological Evaluation of Piperazinylprop- 1-en-
2-yloxy-2H-chromen-2-ones as Cytotoxic Agents. Letters in
Drug Design & Discovery. Oct 2017; 14: 1195-1205. (1.17)
Palak Patel, Krupali Parmar, Vivek K. Vyas, Dhaval Patel, Mili
Das. Combined in silico Approaches for the Identification of
Novel Inhibitors of Human Islet Amyloid Polypeptide (hIAPP)
Fibrillation. Journal of Molecular Graphics and Modelling.
Oct 2017; 77:295-310. (1.754)
Vishnu N Thakare, Manoj K Aswar, Yogesh P. Kulkarni, Rajesh
R Patil, Bhoomika M. Patel. Silymarin Ameliorates
Experimentally Induced Depressive like Behavior in Rats:
Involvement of Hippocampal BDNF Signaling, Inflammatory
Cytokines and Oxidative Stress. Physiology and Behavior. Oct
2017; 179: 401-410. (2.835)
Neha Shah, Tejal Mehta, Rahul Aware and Vasant Shetty.
Investigation on Influence of Wurster Coating Process
Parameters for the Development of Delayed Release
Minitablets of Naproxen. Drug Development and Industrial
Pharmacy. Oct 2017; 43(12): 1989-1998. (2.295)
Anita K. Bakrania, Bhavesh C. Variya, Snehal S. Patel. DEAE-
Dextran Coated Paclitaxel Nanoparticles act as
Multifunctional Nano System for Intranuclear Delivery to
Triple Negative Breast Cancer through VEGF and NOTCH1
Inhibition. European Journal of Pharmaceutics and
Biopharmaceutics. Oct 2017; 122: 37-48. (4.159)
Anita K Bakrania, Surender Nakka, Bhavesh C Variya,
Prabodh V Shah, Snehal S. Patel. Antitumor Potential of
Herbomineral Formulation against Breast Cancer:
Involvement of Inflammation and Oxidative Stress. Indian
Journal of Experimental Biology. Oct 2017; 55: 680-687. (1.1)
Ankit Borisa, Hardik Bhatt. A Comprehensive Review on
Aurora Kinase: Small Molecule Inhibitors and Clinical Trial
Studies. European Journal of Medicinal Chemistry. Nov 2017;
140:1-19. (4.519)
Deepa K. Ingawale, Snehal S. Patel. Hecogenin Exhibits
Anti-Arthritic Activity in Rats through Suppression of Pro-
inflammatory Cytokines in Complete Freund’s Adjuvant-
Induced Arthritis. Immunopharmacology and
Immunotoxicology. Dec 2017; 1:1-13. (1.475)
Anita K. Bakrania, Bhavesh C. Variya, Snehal S. Patel. Role of
b-Interferon Inducer (DEAE-Dextran) in Tumorigenesis by
VEGF and NOTCH1 Inhibition along with Apoptosis
Induction. Frontiers in Pharmacology. Dec 2017; 8: 930-946.
(4.4)
Tejal Rawal, Laurent Kremer, Iman Halloum, Shital Butani.
Dry-Powder Inhaler Formulation of Rifampicin: An Improved
Targeted Delivery System for Alveolar Tuberculosis. Journal
of Aerosol Medicine and Pulmonary Drug Delivery. Dec
2017; 30(6): 388-398. (3.041)
Renuka Mishra, Kripali Soni, Tejal Mehta. Mucoadhesive
Vaginal Film of Fluconazole using Cross-linked Chitosan and
Pectin. Journal of Thermal Analysis and Calorimetry. Dec
2017; 130: 1683-1695. (1.953)
Nikum D. Sitwala, Vivek K. Vyas, Bhavesh C. Variya, Snehal
S. Patel, Chirag C. Mehta, Dharmraj N. Rana, Manjunath D.
Ghate. Liquid Phase Combinatorial Synthesis of 1,2,5-
Trisubstituted Benzimidazole Derivatives as Human DHODH
Inhibitors. Bioorganic Chemistry. Dec 2017; 75: 118-126.
(3.231).
Palak K. Parikh, Manjunath D. Ghate. Recent Advances in
the Discovery of Small Molecule c-Met Kinase Inhibitors.
European Journal of Medicinal Chemistry. Jan 2018; 143:
1103-1138. (4.519).
Samir Rabadiya, Shraddha Bhadada, Ashvin Dudhrejiya,
Devendra Vaishnav, Bhoomika M Patel. Magnesium
Valproate Ameliorates Type 1 Diabetes and Cardiomyopathy
in Diabetic Rats through Estrogen Receptors. Biomedicine &
Pharmacotherapy. Jan 2018; 97: 919-927. (2.759)
Harshil Shah, Jignasa Savjani. Recent Updates for Designing
CCR5 Antagonists as Anti-Retroviral Agents. European
Journal of Medicinal Chemistry. Jan 2018; 147: 115-129.
(4.519)
Surmil Shah, Bhumika Patel, Jignasa K. Savjani.
Pharmacophore Mapping Based Virtual Screening,
Molecular Docking and ADMET Studies of ROCK II Inhibitors.
Multiple Sclerosis and Related Disorders. Feb 2018; 21: 35-
41. (2.349)
One Act Play - Second Prize Trophy
Harvard Internship Programme
Prime Minister's Fellowship
Khorana Scholarship
ACS Travel Grant
Mr. Vandit ShahMs. Khushali ParekhMr. Harshil ShahDr. Jignasa Savjani
DIRECTOR'S DESK DIGNITARIESIt is our pleasure to bring out new issue of institute newsletter 'Radiance'. Institute of Pharmacy always
strives to achieve excellence in Teaching and Research. Several issues about Interdisciplinary research as thwell as opportunities were discussed in 4 Nirma Institute of Pharmacy International Conference
(NIPICON)-2018. Organization of various events and guest lectures is an example of constant updation.
This time also students at Institute of Pharmacy received prizes in One act play. The major highlight in
the student performance includes Ms. Khushali Parekh receiving Prime Minister's Fellowship from
Department of Science and Technology, Mr. Harshil Shah receiving Khorana scholarship from DBT and
Mr. Vandit Shah receiving summer internship from Harvard Stem Cell Institute, Harvard University,
Cambridge, USA. I am sure the Institute will achieve greater heights in future.
(Dr. Manjunath Ghate)
Director, Institute of Pharmacy
It is indeed a pleasure to bring out the second issue of the Eleventh volume of 'Radiance'. It is said that
Excellence is something to be strived to achieve. Institute of Pharmacy organizes various conferences,
seminars and guest lectures for the same. Various achievements of faculty members, staff members and
students also verifies it. I am thankful to all the members of the editorial board for contributing
positively to bring out this issue.
Your suggestions and feedback are always welcome at [email protected]
(Dr. Renuka Mishra)
thFollowing Dignitaries visited Institute of Pharmacy, Nirma University from January 23-25, 2018 during 4 Nirma Institute of Pharmacy
International Conference (NIPICON)-2018 on the theme "Innovation in Pharmaceutical Research by Interdisciplinary Approach "
Dignitaries Visited
Editor’s desk
02 03
Prof. Y. K. Gupta, Professor and Head,
Department of Pharmacology and President,
Indian Society of Nanomedicine, New Delhi on
November 23, 2017
Dr. Daniel G. Miller, President and
CEO, Excorp Medical International
Pvt. Ltd, Singapore
Dr. Neelima Chauhan, Associate
Professor, Department of
Pediatrics, University of Illinois,
USA
Prof. Bhushan Patwardhan,
Director, Center for Complementary
and Integrative Health, Interdisciplinary
School of Health Sciences, Savitribai
Phule Pune University, Pune, India
Dr. Sunil S. Jambhekar, Professor,
Pharmaceutical Sciences, LECOM
School of Pharmacy, Bradenton,
Florida, USA
Prof. Anamik Shah, Vice-
Chancellor, Gujarat Vidyapith,
Gujarat, India
Dr. Mukul Jain, Senior Vice
President & Head, Nonclinical
Research & Development, Zydus
Research Centre, Ahmedabad,
Gujarat, India
Dr. Eric Kupferberg, Vice President
and Director of India Partnership
Programs at Cambridge Graduate
University International (CGUI), USA
Dr. Sabu Thomas, Pro-Vice Chancellor,
Mahatma Gandhi University,
Kottayam, Kerala, India
Dr. Shivprakash Rathnam,
Managing Director, Synchron
Research Services Pvt. Ltd.,
Ahmedabad, Gujarat, India
Dr. Nikolaos Kostopoulos,
Managing Director, Holistic Health
Centre, Athens, Greece
Dr. Harish Padh, Former Vice
Chancellor, Sardar Patel University,
Vallabh Vidyanagar, Gujarat, India
Dr. S. V. Gopalakrishnan, Senior
Vice-President, Zydus Cadila,
Ahmedabad, Gujarat, India
Prof. S. H. Ansari, Faculty of Pharmacy,
Jamia Hamdard, New Delhi on
December 2, 2017
Dr. Sen Pathak, Distinguished Research
Professor, Department of Genetics, The
University of Texas, USA visited on
February 7, 2018
DIGNITARIES EXPERT LECTURES
04 05
Name of the Expert, Designation and Organization Topic Date
Prof. M. V. Ramana,
Former Director and Professor, Amity University, Lucknow
Dr. Satyendra Mishra,
Assistant Professor, Chemistry Department, University Design of Peptidomimetic Drugs November 9, 2017
and Institute of Advanced Research, Gandhinagar
Dr. Sharad Gupta, The Role of Post Transnational Modifications
Assistant Professor, IIT, Gandhinagar (PTMs) in Neurodegenerative disorders November 13, 2017
Dr. D. D. Santani, Former Director (Academic), Insulin and Hypoglycemic agents November 20, 2017
ISF College of Pharmacy, Moga, Punjab
Dr. Munira Momin, Principal, SVKM's Functionalized Nanoparticles for November 20, 2017
Dr. Bhanuben Nanavati College of Pharmacy, Mumbai Brain Targeting
Dr. Brijesh Srivastava, Deputy General Manager, Recent strategies for the Design of November 24, 2017
Zydus Research Centre, Ahmedabad Anti-Cancer Agents with a Support of
Case Study of ZYTP1
Dr. Sanjay Kumar, General Manager, Role of Stereochemistry in Drug Design November 29, 2017
Department of Medicinal Chemistry, & Development
Zydus Research Centre, Ahmedabad
Prof. Gaurang B. Shah, Screening of Anti-Cancer Agents November 27, 2017
Professor, L.M.College of Pharmacy, Ahmedabad
Ms. Leena Sharma, Manager – Strategic Marketing Role of Biochemistry in Drug Discovery November 27, 2017
Piramal Enterprises Ltd, Piramal Discovery Solutions
Ahmedabad
Dr. R. K. Parikh, Former Head, Preformulation Study : Important Tool November 27, 2017
Department of Pharmaceutics, for Formulation Development
L.M. College of Pharmacy Ahmedabad
Mr. Anay Mashruwala, Partner, Head Marketing & Business Plans – Development Incubation November 27, 2017
Quality Control, M/s. Venus Engineering Works, Ahmedabad
Dr. Anita Mahapatra, Assistant Professor, Chemistry and Drug Development from November 28, 2017
Dept. of Natural Products, the Class of Alkaloids and Terpenoids
National Institute of Pharmaceutical
Education and Research, Ahmedabad
Prof. Rakesh S. Srivastava, Head, Department of Bio-statistic Principle Applied in December 1, 2017
Computer Applications, M.S. University, Vadodara Clinical Research
Dr. Anupama Ramkumar, Director, Medical Writing January 8, 2018
Arkus Research Pvt. Ltd., Ahmedabad
Mr. Vipin Sharma, cGMP, Validations & Data Integrity January 12, 2018
Doshi Consultant Pvt. Ltd, Ahmedabad
Prof. Sunil Jambhekar, Professor, Applications of Pharmacokinetics in Research January 31, 2018
LECOM School of Pharmacy, Bradenton, Florida, USA
Solubility Enhancement Technique October 9, 2017
Dr. Ajay Khopade, Vice President-
Formulations, Sun Pharma
Advanced Research Company Ltd,
Vadodara, Gujarat, India
Dr. Bipin Pandey, Director, Center
of Excellence Adjunct Professor,
Department of Chemistry,
Saurashtra University, Rajkot,
Gujarat, India
Dr. Manoj K Mishra, Director,
Cancer Biology Research and
Training program, Department of
Biological Sciences, Alabama State
University, Montgomery, USA
Dr. Nandakumar Kalarikkal,
Director, International and
Inter University Centre for
Nanoscience and
Nanotechnology, Mahatma
Gandhi University, Kottayam,
Kerala, India
Dr. Bhaswat Chakraborty, Former
Senior Vice-President & Chair,
Cadila Pharma. Ltd, Ahmedabad
Dr. Prabhudas Patel, Professor &
Head, Department of Cancer
Biology, Gujarat Cancer &
Research Institute, Ahmedabad,
Gujarat, India
Dr. Balvantsinh Chauhan, Faculty,
College of Pharmacy, Roosevelt
University, USA
Dr. Sivapriya Kirubakaran,
Assistant Professor,
Chemistry &
Bioengineering, Indian
Institute of Technology (IIT)-
Gandhinagar, Gujarat, India
Dr. Jyoti Paliwal, Consultant, PhaEx,
Ahmedabad, Gujarat, India
Dr. M.T. Chhabria, Principal, L.M.
College of Pharmacy, Ahmedabad,
Gujarat, India
Dr. Maya Nair, Assistant Director,
Department of Environment
Health and Safety, University of
North Texas Health Science
CenterFort Worth, Texas, USA
Dr. Kiran Marthak, Global
Head – Clinical
Development, Lambda
Therapeutic Research
Limited, Ahmedabad,
Gujarat, India
Dr. Lal Hingorani, MD and Director,
Pharmanza Herbal Pvt Ltd,
Dharmaj, Gujarat, India
Dr. Manish Nivsarkar, Director,
B.V.Patel PERD Centre,
Ahmedabad, Gujarat, India
Dr. Vijay Raina, Senior Director,
Nektar Therapeutics India Private
Limited, Hyderabad, India
Dr. Nina Sharma,
Managing Director,
Shamisha Resources
Management, Ahmedabad,
Gujarat, India
Dr. Rakesh Rawal,
Professor, Department of
Life Sciences, Gujarat
University, Ahmedabad,
Gujarat, India
EVENTS EVENTSFoundation Day Celebrations
Anti-Ragging Poster Competition
Industrial Visit
Institute of Pharmacy, Nirma University celebrated its
Foundation Day on October 4, 2017. The day started with
inaugural function graced by the Chief Guest Shri Sirish G.
Belapure, Managing Director, Zydus Hospira Oncology Pvt.
Ltd. Prominent faculty members, Alumni members and
students were felicitated for their achievements. The events
included poetry competition, extempore competition and
debate competition Overall, it was an enjoyable experience
throughout the day which encouraged us for taking the
challenges in the upcoming time.
The anti-ragging poster competition was organized at the
Institute of Pharmacy, Nirma University on October 13, 2017.
Around 85 students participated enthusiastically in the event
and the competition was judged by Ms. Sujan Umaraniya,
Assistant Professor, Institute of Architecture, Nirma
University and Dr. Shital Panchal, Assistant Professor,
Institute of Pharmacy, Nirma University. The selected posters
were displayed on the notice board.
Educational Institute needs to cater diversified requirements
of the students. During graduation, students understand the
profession and thus teach varied subjects starting from basic
to advanced. In the technical field like Pharmacy, students
are taught theory as well as trained to perform various
practical. In addition to above all, students visited various
industries and institutes to understand the functioning of
the same. Visits to Nivea India Ltd, Sanand for B. Pharm
semester-VII students on November 18, 2017 and to B. V.
Patel PERD Center, Ahmedabad for M Pharm semester –I
students on November 28, 2017 were organized.
Good habits can be imbibed during childhood. However, it’s
very sad that many children do not get environment to grow
and understand the difference between what is good and
what is not. Hence, social extension activity is part of
curriculum and our students of B. Pharm semester V visited
Primary school in Jamyatpura village for creating awareness
amongst school children about following:-
• Anti-Tobacco Drive to create awareness about bad effect
of tobacco on health on November 10, 2017.
• Awareness program on Emergency and First Aid was
conducted on November 17, 2017.
• Awareness program on skin care in winters was
conducted and cold cream was distributed among the
students on November 24, 2017.
Extension Activities
National Pharmacy Week Celebration
Workshop on “Application of Analytical
Techniques for Herbal Drugs Research”
Institute of Pharmacy, Nirma University celebrated Gujarat
State Pharmacy Council (GSPC) sponsored National
Pharmacy Week from December 18-22, 2017. The event was
inaugurated by Dr. Jolly Parikh, Professor and Head,
Department of Pharmaceutics, A.R. College of Pharmacy,
Vallabh Vidyanagar and Nominee, GSPC on December 18,
2017. She highlighted various means of creating awareness
of pharmacy profession and role of pharmacist in healthcare
system in her address. Shri MontuKumar Patel, President,
GSPC informed the activities carried out by GSPC for
creating public awareness in relation to pharmacy
professionThe National Pharmacy week celebration included
events like Extempore, Elocution, Expert lecture, Health
check-up and awareness camp. On the last day of the event,
expert lecture by Dr. D. D. Santani, Former Director, ISF
College of Pharmacy, Moga, Punjab was organized where he
informed about the role of pharmacist and opportunities
ahead. The expert lecture was followed by Prize distribution
for Elocution and Extempore competition and feedback by
the students. The students found the program informative
and interesting. Overall, the program was successfully
conducted meeting the aspirations of the budding
pharmacists.
Department of Pharmacognosy, Institute of Pharmacy, Nirma
University organized one day workshop on “Application of
Analytical Techniques for Herbal Drugs Research” on January
6, 2018. Dr. Subrata De, Consultant, Zoetic Ayurvedics Pvt.
Ltd was the chief guest and one of the speakers for the
workshop. He delivered his talk on “Overview on
Applications of Analytical Instruments in Natural Product
Research”. Dr. Rina Gokani, Director & CSO, Accuprec
Research Labs Pvt. Ltd., delivered a talk on the topic “Recent
Advancement in Quality Control of Herbal Medicines”. There
were total 44 students and faculty members who
participated in the workshop from various institutions.
During the workshop participants got the exposure of
various sophisticated instruments like GC, HPLC, HPTLC, FT-
IR and Spectro-flourimetry.
Three days International Conference (NIPiCON –2018) was
organized by Institute of Pharmacy, Nirma University,
Ahmedabad, on the theme of “Innovation in Pharmaceutical
Research by Interdisciplinary Approach” during January 23-
25, 2018. Dr. Dan Miller (VP, Excorp Pvt Ltd, Singapore) was
the Chief Guest for the inaugural function and Dr. Anamik
Shah (Vice Chancellor, Gujarat Vidyapith) was the Guest of
Honour. International eminent speakers like Dr. Eric
Kupferberg, Dr. Nikolaos Kostopoluos, Prof. Sunil Jambhekar,
Dr. Balvantsinh Chauhan, Dr. Maya Nair, Dr. Neelima
Chauhan and Dr. Manoj Mishra delivered talk related to the
theme of NIPiCON 2018. Nationally reputed speakers from
the fields of Pharmaceutical Sciences, Ayurvedic science,
Biological Science etc. shared their knowledge and discussed
avenues of interdisciplinary approaches in Pharmaceutical
research. More than 400 delegates from all over India and
from various fields attended the conference and presented
their research work in poster session during three days. Dr.
Eric Kufenberg (Director, Cambridge Graduate University
USA) was the Chief Guest and Prof. Sunil Jambhekar
(Associate Dean, LECOM School of Pharmacy, Bradenton,
Florida, USA) was the guest of honour of Valedictory
function. The prizes for best posters were presented during
valedictory function. This conference has served as a
platform for sharing of knowledge and ideas in
complementing research areas of Pharmaceutical Sciences
which will encourage young researchers to take up newer
challenges using multidisciplinary approach.
NIPiCON 2018
06 07
EVENTS STUDENT RESEARCH
08 09
IPNUAA meet
Personality Development Sessions
The annual Alumni meet of IPNUAA (Institute of Pharmacy
Nirma University Alumni Association) was organized on
January 26, 2018. More than 90 alumni members joined for
the annual meet. Prof. Manjunath Ghate welcomed all the
Alumni Members and shared the updates of Institute. Dr.
Sunil Jambhekar and Dr. Eric Kupferberg from USA graced
the occasion by their words of wisdom. Alumni members
enjoyed various fun activities arranged by B. Pharm
Students. Few Alumni members shared their feedbacks,
views and achievements. Dr. Dhaivat Parikh shared the
updates about IPNUAA activities and opportunities of
alumni networking. The annual meet ended with delicious
lunch.
Institute of Pharmacy, Nirma University organized series of
sessions on personality and life skills development for
students of 2nd, 3rd and 4th year B. Pharm during January
12-20, 2018. As a part of this series, Mr. Farhat Umar, Chief
Human Resources Officer at Aerolam Insulations Pvt. Ltd.
and Founder of Credo HR solutions interacted with 4th year
students on 'Campus to Corporate’. He also motivated the
2nd year students talking on ‘Effectiveness and Goal setting’.
Mr. Suresh Mashruwala, Professional Commentator and
Trainer, interacted with 3rd and 4th year students on “Public
Speaking and Effective Communication’. Further, Dr. Debjani
Dass, Faculty at B.K. School of Business Management, gave
talk on time management to 2nd year students. Also, Dr.
Nina Muncherjee, Professor, Institute of Management, Nirma
University interacted with 3rd year students on the various
aspects of ‘Team Building’. The students were able to
develop their soft skills and learnt a lot about its importance
in development of their future career.
Institute of Pharmacy, Nirma University organized Refresher
Course for Registered Pharmacist during February 3-4, 2017.
It was attended by more than 180 registered pharmacists
from all over Gujarat. Speakers from industries as well
academics delivered expert talks entitled “Medication
Errors”, “Pharmacovigilance and Adverse Drug Reactions”,
“Clinical Research”, “Patient Counselling on Anti-Tubercular
Drugs”, “Patient Counselling on Anti-Asthmatic”, “Rational
Drug Use” and “Patient Compliance” during the program. It
was highly appreciated by all the participants and turned out
to be a great success.
A workshop on the "Computer Aided Drug Design Software"
was conducted by the Department of Pharmaceutical
Chemistry, Institute of Pharmacy under Center of Continuing
Education, Nirma University on February 17, 2018. The main
objective of the workshop was to provide conceptual insight
as well as demonstration of important software used for
computer aided drug design (CADD). The sessions were
conducted by internal faculties while software
demonstration and hands on training on some CADD tools
were given by research scholars. The workshop received very
good response and total 48 participants attended the
workshop.
Refresher Course for Registered
Pharmacist
Workshop on the "Computer Aided Drug
Design Software
M.Pharm Programme in different disciplines:
No. Project Title Student Guide/Co-guide
Pharmaceutical Technology and Biopharmaceutics
1 Stabilization of Levothyroxin Sodium Tablets Aishwarya Mishra (16MPH101)
2 Formulation, Development and Evaluation of Immediate Ankita Singh Prof. Tejal A. MehtaReleased Tablets containing Hypertensive Agents (16MPH102) Industrial Guide: Ms. Priti Daliin Combination Ipca Laboratories Ltd.
3 To Study the Effect of Different Curing Conditions & Dhruvikumar Solanki Prof. Tejal A. MehtaIts Optimization on Sustained Release Pellets Filled in (16MPH103)Capsule for Gastro-Prokinetic Agent
4 Formulation and Development of Disposable Tablets of Dhwani Desai Dr. Mohit ShahAnti-Malarial Drug Belonging to BCS Class III (16MPH104) Industrial Guide: Subhrangshu Sengupta,
Ipca Laboratories Ltd.
5 Design, Development and Characterization of Immunosuppressant Harshil Shah Dr. Renuka D. MishraDrug Formulation using Microfluidizer as a Technology (16MPH105) Industrial Guide: Dr. Subhash Ghore,
Lupin Research Park
6 Development of Nanoparticle Based Vaginal Film Formulation Jagat Maniyar Dr. Renuka D. Mishra(16MPH106)
7 Improvement of Palatability for Oral Oil Based Formulation Kartik Hariharan Prof. Tejal A. Mehta(16MPH107) Industrial Guide: Mr. Sumit Madan
Sun Pharmaceuticals
8 Formulation Development & Evaluation of Immediate Nidhi Patel Dr. Mohit ShahRelease Tablet Containing Anti-hypertensive Agent (16MPH108) Industrial Guide: Mrs. Priti Dali,
Ipca Laboratories Ltd.
9 Studies on the Effect of Process Variables in Scale-up Nidhish Patel Dr. Dhaivat C. Parikhfor Fluid Bed Processor (Wruster Coating) (16MPH109) Industrial Guide: Shri Ritesh Kapoor
Cadila Healthcare (Zydus) Pvt. Ltd.
10 Design, Development and in vitro Evaluation of Niharika Devli Dr. Jigar N. ShahCompression Coated Technique in Comparison with (16MPH110)Conventional Coating Technique
11 Evaluation of Powder Drug Layering Technique as Possible Nimesh Saripadiya Dr. Mayur M. PatelMeans of Abuse Deterrent Formulations (16MPH111) Industrial Guide : Anuj Fanda, Kartik Parsa
12 Formulation and Evaluation of Stable Lyophilized Rasesh Patel Dr. Jigar N. ShahInjectable Dosage Form containing Antibiotic Drug (16MPH112) Industrial Guide :
Dr. Nitin Dobaria, Zydus Cadila
13 Formulation Development and Optimization of Riddhi Patel Dr. Shital B. ButaniDelayed Release Capsule of Proton Pump Inhibitor (16MPH113) Industrial Guide : Hiren Bhagat,
Cadila Healthcare Pvt Ltd
14 Design Formulation and Evaluation of Soluble, Shivangi Kaul Dr. Shital B. ButaniSunconjuctival Implants of Fluroquinolone Antibiotic ((16MPH114) Industrial Guide : Ms. Mona
Dhaliwal, Sun Pharmaceuticals
15 Formulation, Development and Optimization of Immediate Smit Gandhi Dr. Mayur M. PatelRelease Tablet for Schizophrenia and Bipolar Disorders (16MPH115) Industrial Guide : Dr. Suprit Sauoji
Alkem Laboratories P. Ltd, Mumbai
16 Formulation and Development of Orodispersible Virajkumar Makwana Dr. Dhaivat C. ParikhTablet for Treatment of Migraine (16MPH116) Industrial Guide : Mr. Sanjaykumar
Sahu Alkem Laboratories Pvt. Ltd, Mumbai
Pharmacology
1 Investigation of the Role of Trans-anethole in Aakanksha Jadaun Dr. Shraddha BhadadaCardiac Hypertrophy (16MPH201)
2 Effect of Clodronate on infiltrating monocyte mediated Ashwati Nair Dr. Jigna Shahchronic unpredictable stress induced depression (16MPH202) Dr. Anilkumar Pillai, USA
Prof. Tejal A. Mehta
STUDENT RESEARCH STUDENT RESEARCH
10 11
9 Comparison of Safety and Efficacy of Capecitabine in Conventional (2/1) V/S Continuous Dosing in Metastatic Breast (16MPH710) Hospital Guide: Dr. Chirag Desai, and Colorectal Cancer Patients Vedanta Institute of Medical
Science and Research, Ahmedabad
Regulatory Affairs & Quality Assurance
1 Question Based Review (QbR) and the Role of QbR in Alisha Desai Dr. Priti Mehtaimplementing Quality by Design (QbD). (16MPH801) Industrial Guide: Dr. Kanhoba Walavalkar,
Sun Pharmaceuticals, Mumbai
2 Overview to Environmental Impact Assessment (EIA) Angana Shastri Dr. Priti Mehtaof Veterinary Medicinal Products (VMP's). (16MPH802) Industrial Guide: Mr. Nirav Chokshi,
Cadila Healthcare Limited, Ahmedabad
3 Filing of Type-II Drug Master File of ‘X’ Drug for US Market Deepak Pareek Dr. Nrupesh Patel(16MPH803) Industrial Guide: Mr. Darshan Aigal
Cipla Limited, Mumbai
4 Regulatory Submission Pathways in Europe and its Jaya Devnani Dr. Priti Mehta,Utilization outside Europe. (16MPH805) Industrial Guide: Mr. Nirav Chokshi,
Cadila Healthcare Limited, Ahmedabad
5 A Comprehensive Comparative Review of Food Khushbu Jani Dr. Charmy KothariRegulation in India and USA (16MPH806) Industrial Guide: Mr. Nirav Choksi,
Cadila Healthcare Limited, Ahmedabad
6 WHO Prequalification Programme Krishna Shah Dr. Priti Mehtafor Vaccines. (16MPH807) Industrial Guide: Mr. Nirav Chokshi
Mr. Himanshu Suthar. CadilaHealthcare Limited, Ahmedabad
7 Regulatory Strategy for Complex Medicines for Labdhi Shah Dr. Nrupesh PatelEurope and its Evaluation Post Brexit (16MPH808) Industrial Guide: Mr. A. V. Hargopal
Intas Pharmaceuticals Limited, Ahmedabad
8 Evolution of ANDA Submission and Impact of Nishita Majmudar Dr. Nrupesh PatelCurrent Guidance on Approval Process (16MPH809) Industrial Guide: Mr. Deepak Jain
Cadila Healthcare Limited, Ahmedabad
9 Generic Drug Labeling: Components and Niyati Mehta Dr. Priti MehtaExpectations of USFDA. (16MPH810) Industrial Guide: Mr. Deepak Jain
Cadila Healthcare Limited, Ahmedabad
10 Regulatory Regime on Indian Medical Device Industry Purva Dahapute Dr. Nrupesh Patel- A Way Forward and Comparison (16MPH811) Industrial Guide: Mr. Hiren Patel
Meshayu Consultants P. Ltd., Ahmedabad
11 Regulatory Filing Requirements & Dossier Compilation Riya Sanjaykumar R Dr. Charmy Kotharifor Parenteral Dosage Form for USA market (ANDA) (16MPH812) Industrial Guide: Mr. Pratik Vora
Intas Pharmaceuticals Ltd., Ahmedabad
12 Comparative Study of Lifecycle Management in Samarth Dalal Dr. Charmy KothariRegulated Market Europe, Australia, USA and to (16MPH813) Industrial Guide: Mr. Ragib EhsanStudy the Filing and Submission Procedure Alkem Laboratories Ltd.
13 A Comprehensive Study on Regulatory Requirements Shriya Mohidekar Dr. Nrupesh Patelfor Medical Devices in IMDRF countries and (16MPH814) Industrial Guide: Dr. PraveenKumar L.a Comparative Analysis Cipla Limited, Mumbai
14 Maintainence of Marketing Authorization in ROW Suruchi Lele Dr. Charmy KothariCountries with Emphasis on Re-registration Requirements (16MPH815) Industrial Guide: Mrs. Charuta Acharekar,
Cipla Limited, Mumbai
15 Filing of Irbesartan Tablet in Module 3 Vinamrata Dr. Charmy Kotharifor ANDA Submission Raghuvanshi Industrial Guide: Mr. Anurag Malviya,
(16MPH816) Ipca Labs Ltd Pithampur, Indore
Suraj Shival Dr. JIgna Shah, 3 Evaluation of HDAC Inhibitors in Cancer Cachexia and Associated Cardiovascular Complications (16MPH203)
4 Pharmacological Evaluation of Hesperidin and Febuxostat Kinal Soni Dr. Jigna Shahin Breast Cancer (16MPH204)
5 Effect of Sodium Orthovanadate as PTP1B Inhibitor in Kruti Patel Dr. Bhoomika M. PatelColon Cancer Associated with Diabetes Mellitus (16MPH205)
6 Evaluation of Beneficial Effect of Trans-anethole in Monika Thesiya Dr. Shraddha BhadadaDiabetes Induced Cardiac Fibrosis (16MPH206)
7 Pharmacological Evaluation of Anti-Diabetic Agents Nisarg Korat Dr. Jigna ShahAgainst Experimentally Induced Alzheimer’s Disease ((16MPH207)
8 Functional role of indomethacin derivatives in treatment Priyanka Nanavati Dr. Snehal Patelof hepatocellular carcinoma (16MPH208)
9 Investigation of Pharmacological Actions of Withaferin A Raj Joshi Dr. Shital Panchalin AlCl3 induced Alzheimer’s Disease. (16MPH209)
10 Protective role of calcium channel blockers in diabetes Rashmi Rajput Dr. Snehal Patelassociated cerebrovascular complications (16MPH210)
11 Evaluation of Pharmacological Effects of Curcumin and Shreya Zinzuwadiya Dr. Shital PanchalCow’s Ghee in AlCl3 induced Neurodegeneration (16MPH211)
Medicinal Chemistry
1 Design and Synthesis of Hybrid Molecules for the Treatment Anas Maniar Prof. Manjunath Ghateof Tuberculosis. (16MPH401) Ms. Palak K. Parikh
2 Design and Synthesis of Novel Tankyrase Ankitkumar Patel Dr. Hardik BhattInhibitors for the Treatment of Cancer (16MPH402) Dr. Bhumika Patel
3 Design and Synthesis of DNA gyrase Inhibitors Harsh Rathnam Dr. Jignasa Savjanias Anti-microbial Agents (16MPH403) Ms. Palak Parikh
4 Design, Synthesis of Novel Heterocyclics as Inducer of Hirenkumar Dayani Dr. Vivek K. VyasApoptosis And Anticancer Agents (16MPH404)
Clinical Pharmacy
1 Relative evaluation of drug utilization pattern and design Apal Dave Dr. Snehal Patel of the primary prevention strategies for promising (16MPH701) Hospital Guide: Mr. Nipul Kapadiajudicious use of various drugs
2 Evaluation of Pregabalin for the Treatment of Radicular Hemangi Raval Dr. Bhoomika M. PatelPain Comparative Evaluation of Tizanidine and (16MPH702) Hospital Guide: Dr. Nehal ShahBaclofen in Spasticity
3 Prevalence of Anemia in Pre-school Tribal Children and its Juhi Sharma Dr. Shital PanchalAssociation with Malnutrition and Genetic (16MPH703)Hemoglobin Disorders
4 Prevalence of Depression in Patients with Diabetes Mellitus Kavisha Raval Dr. Snehal Patel and its Impact on Quality of Life (16MPH704) Hospital Guide: Dr. Banshi Saboo
5 Prevalence of Alzheimer Diseases, Dementia and MCI Madhvi Jamariya Dr. Jigna Shahdisorders in Patient suffering from Diabetes Mellitus (16MPH705) Hospital Guide: Dr. Kamal Sharma, having CAD in Ahmedabad Region. Sanjivani Hospital, Ahmedabad
6 Evaluation of Risperidone in Children with Autism Rudri Joshi Dr. Bhoomika M. Pateland/or Attention Deficit Hyperactive Disorder. (16MPH706)
7 Determination of Prevalence and Risk factors Contributing Shivani Patel Dr. Shraddha Bhadadato Hypertensive Disorders in Pregnancy in Female (16MPH707) Hospital Guide: Dr. Uma Khatri,Patients in Ahmedabad region. Jeevan deep Hospital, Ahmedabad
8 Prevalence of Anemia in Pre-school Tribal Children and Shrishma Chaudhary Dr. Shital Panchalits Association with Gastrointestinal Infections. (16MPH708)
Dhwani Patel Dr. Bhoomika M. Patel
STUDENTS' CORNER STUDENTS' CORNER
12 13
Ph.D. awarded:
Students’ Achievements:
Following students received Ph.D. degree during the Twenty
Fourth Convocation of Nirma University-
Mr. Sandeep Kumar Thakur on
“Identification of Biomarkers for Early
Detection of Drug Induced Hepatotoxicity”
under the guidance of Dr. Manish Nivsarkar
Ms. Vrundaben Chetankumar Suthar on
“Development and Evaluation of Self
Emulsifying Drug Delivery Systems of
Lercanidipine HCI to Improve Dissolution in
Bio-Relevent Media” under the guidance of Dr.
Shital Butani
Mr. Saurabh Agarwal on “Comparative Study
of Centrally Acting Muscle Relaxants in
Spasticity Associated with Post-Stroke,
Cerebral Palsy & Spinal Cord Injury” under the
guidance of Dr. Bhoomika M. Patel
Mr. Jitendra Onkar Bhangale on “Study of
Novel Scaffolds from Natural Product for the
Treatment of Neurodegenerative Diseases”
under the guidance of Dr. Sanjeev Acharya
Mr. Brijesh Maheshkumar Shah on
“Instranasal Colloidal Drug Delivery System
For Brain Targeting Of Drugs” under the
guidance of Dr. Harish Padh
Ms. Manika Kala on “Role of Stress and Stress
Hormones on Ovulation and Implantation in
Mice: Involvement of Adrenals” under the
guidance of Dr. Manish Nivsarkar
Mr. Shaikh Muhammad Vaseem on
“Targeting Drug Resistant Cancer Stem-Like
Cells using Nanoparticles: A Novel Strategy
For Anticancer Treatment” under the guidance
of Dr. Manish Nivsarkar
Mr. Vishnu Namdeorao Thakare on
“Pharmacological Evaluation of Silymarin and
Protocatechuic Acid in Experimentally Induced
Depression in Rodents” under the guidance of
Dr. Bhoomika M. Patel
Ms. Anita Bakrania on “Investigation and
Evaluation of Interferon Inducer Alone and in
Combination with Chemotherapeutic Agents
as a Targeted Anti-Cancer Therapy” under the
guidance of Dr. Snehal Patel
Mr. Vandit Shah, B.Pharm semester-VI student received
Harvard Internship Programme (HIP) summer internship
from Harvard Stem Cell Institute, Harvard University,
Cambridge, USA. He will be receiving 4500 dollars as
fellowship.
student received Consolation prize (First) in Photograhy &
Short Film Competition held on January 16, 2018 by Student
Welfare Activities at Nirma University.
Ms. Swati Patil and Ms. Kosha Prajapati, B.Pharm
semester-IV students participated as NCC cadet and
performed piloting duty for the chief guest Shri Mukesh
Patel, Well known Tax consultant during Republic day
celebration on January 26, 2018.
Ms. Rutu Panchal, B.Pharm semester - VI student and Ms.
Bhumi Akhani, B.Pharm semester-VIII student received
First and Second prize respectively in Quiz Competition on
the occasion of World Cancer Day celebrated from
February 5 to February 9, 2018 by Library Resource Centre,
Institute of Pharmacy, Nirma University.
Drama club students of Institute of Pharmacy, Nirma
University performed and participated in the inter institute
one act play competition as a part of celebration of Republic
Day on the theme "Equal Opportunity" coordinated by Dr.
Dipal Gandhi, Coordinator Drama club and over all event
coordinator, One Act Play-2018. Total 7 teams from different
Institutes participated and Institute of Pharmacy students
Drama Club Activity
won 3 Trophies including Best One Act Play (2nd Prize) (Title
of Play- Naam Bada ya Kaam?) (Participants- Siddharth
Talati, Akruti Sharma, Haard Patel, Umang Patel, Prashil
Panchal, Rohit Manshani, Shrey Shah, Pooja Mehta, Jay Patel,
Akash Patel, Jay Shah, Shrey Modi), Best Supporting Actor
(Female) (Aakruti Sharma), Best Production (2nd Prize) (Rushi
Joshi, Smit Patel, Kathan Patel).
Mr. Harshil Shah, M.Pharm semester-II student received
Khorana Scholarship from the Department of Biotechnology
(DBT), IUSSTF for summer internship in 2018 at University of
North Carolina, USA for 10-12 weeks. This scholarship will
include round trip airfare, stipend of $2500, health insurance
of $500 and accommodation allowances.
Ms. Khushali Parekh, PhD student received prestigious
‘Prime Minister’s Fellowship for Doctoral Research’
scholarship, a unique scholarship of Science & Engineering
Research Board, Department of Science and Technology,
Government of India and Confederation of Indian Industry
on “Development of Topical Nanoformulation and its
efficacy studies for the treatment of Atopic Dermatitis” for
four years duration.
Ms. Viral Shah, PhD student received second thprize in the best poster category at 16
International Symposium on Advances in
Technology and Business Potential of New
Drug Delivery Systems organized by
Controlled Release Society-Indian Chapter,
Mumbai during February 23-24, 2018.
Mr. Nisith Raval, PhD student received
Junior Research Fellowship on Glutathione
appended polymeric nanoconstructs of
asiatic acid for efficacious neuroprotection against
Alzheimer's disease” from Department of Biotechnology
from October 21, 2017 for two years. Mr. Nishith Raval also threceived second runner-up in best poster award at 16
International Symposium on Advances in Technology and
Business Potential of New Drug Delivery Systems organized
by Controlled Release Society-Indian Chapter, Mumbai
during February 23-24, 2018.
Ms. Sushama Rawat, PhD student received
Junior Research Fellowship on “Design and
synthesis of Benzimidazole derivatives as
Anti-Cancer Agents” from Nirma University
from November, 2017.
Ms. Dhara Bhayani, PhD student received
First prize in poster competition in the track
Pharmaceutical Analysis and Quality
Assurance in NIPiCON 2018 held from
January 23-25, 2018.
Mr. Pruthakkumar Joshi, B. Pharm semester-IV student
participated in Gujarat quiz contest 2017 held on September
29, 2017 and received First rank at district level.
Ms. Ananya Shah, B.Pharm semester-IV student received
Third prize and Mr. Maharshi Patel, B.Pharm semester-IV
Students were awarded for the best scholastic performance during their study at the Institute of Pharmacy during the
convocation ceremony of Nirma University. The following were the shining stars :
Other felicitations on Foundation Day include:
• Khyati Ashtekar and Bhumi Akhani were felicitated as best student of the year for their outstanding academic performance
and maximum participation in extracurricular and co-curricular activities.
• Dr. Priyanka Trivedi, Dr. Mukta Asnani, Dr. Alok Shah, Dr. Urvish H. Desai, Mr. Tushar Patel and Mr. Manish Bhadani were
felicitated as alumni with outstanding achievements.
Institute of Pharmacy, Nirma University felicitated the students with gold medals for their scholastic performance during the
respective years on the occasion of Foundation Day October 4, 2017:
M.Pharm Best scholastic performance
Pharmaceutical Technology and Bio-Pharmaceutics Ms. Dolly Jetha
Clinical Pharmacy Ms. Vruti Patel
Pharmaceutical analysis Mr. Prabhatsingh Rajput
Regulatory affairs and Quality Assurance Ms. Krishna Trivedi
B. Pharm Ms. Kanchan Maurya
B.Pharm year Name of the student Semester
First year Ms. Jahnvi Patel III
Second year Ms. Anjali Yadav V
Third year Ms. Tamhida Masi VII
FACULTY CORNER FACULTY CORNER
14 15
Faculty Achievements:
Ph.D. Awarded
Faculty Recognitions
Expert Lecture delivered by Faculty:
Book Published:
Staff Achievements
Dr. Bhoomika M. Patel has been appointed as CPCSEA
Nominee by Ministry of environment, forest, climate change
(Animal welfare division A) in February 2018.
Dr. Hardik Bhatt delivered a talk entitled “Strategy for
Development of Dual Kinase Inhibitors for Cancer Treatment”
at National Conference on Materials in Chemistry and
Biologics organized by Indian Institute of Technology,
Gandhinagar on January 4-5, 2018.
Dr. Bhoomika M. Patel delivered a talk entitled “HDAC and
Cancer Cachexia: Is there a link?” at Golden Jubilee Concluding
Celebrations and Annual Conference of Indian
Pharmacological Society (IPSCON-2017) organized by
Shobhaben Pratapbhai Patel School of Pharmacy and
Technology Management, SVKM's NMIMS University, Mumbai
on February 15-17, 2018.
"Pharmaceutical Quality Management and Drug delivery
System" by SK Kar, Tejal Mehta, Munira Momin. First edition,
Career Publication, Nashik, Maharashtra. Date of Publication :
January, 2018.
Mr. Virendrakumar S. Goswami, Assistant Librarian
presented a paper entitled “Use of Social Media Technology in
Nirma University's Libraries: a Study” in two days International
Conference on The Journey of Indian Languages: Perspectives
on Culture and Society at Dr. Babasaheb Ambedkar Open
University, Ahmedabad during October 14-15, 2017.
Faculty Felicitation during foundation day
Dr. Vivek Vyas was felicitated for publishing research article in
highest impact factor journal (4.55) Arabian Journal of
Chemistry and for highest feedback (4.79) from students
amongst all faculty members of Institute of Pharmacy, Nirma
University.
Dr. Charmy Kothari was felicitated publishing a review article
in highest impact factor journal (8.44) in Trends in Analytical
Chemistry
Dr. Priti Mehta was felicitated for receiving major research
grant from Ministry of Ayush worth Rs. 42,12,000/- and from
SAC-ISRO worth Rs. 16,00,000/-.
Dr. Jigna Shah was felicitated for receiving major research
grant worth Rs. 20,81,000/- from Gujarat State Biotechnology
Mission (GSBTM).
Dr. Shital Panchal was felicitated for receiving major research
grant worth Rs. 18,60,000/-from Indian Council of Medical
Research (ICMR) and for getting highest consultancy project
worth Rs. 2,70,000/- from Pharmanza Pvt. Ltd., Ahmedabad
Dr. Jigar Shah was felicitated for Best Presentation Award at th18 International Conference on Pharmacology and
Pharmaceutical Medicine at Vancouver, Canada and receiving
Travel grant worth Rs. 1,00,000/- from Indian Council of
Medical Research (ICMR).
Mr. Hasmukh Rathod and Mr. Jignesh Patel were felicitated
for their outstanding performance in Special Recognition for
non-teaching staff category.
Travel Grant received
Dr. Jignasa Savjani received prestigious ACS (American Chemical Society) travel grant worth Rs. 2.5 lacs to attend Pittcon 2018
conference held at Orlando, United states of America, during February 26 to March 1, 2018.
Mr. Nrupesh Patel, Assistant Professor, has been awarded
Doctor of Philosophy (Ph.D.) in Pharmacy by Nirma
University, Ahmedabad, Gujarat in October, 2017 for his
thesis entitled “Analytical Method Development, Validation
and Degradation Studies of Dosage Forms of Montelukast
and Desloratadine” under the guidance of Prof. Anuradha
Gajjar.
Ms. Nagja Tripathi, Assistant Professor, has been awarded
Doctor of Philosophy (Ph.D.) in Pharmacy by Nirma
University, Ahmedabad, Gujarat in December, 2017 for her
thesis entitled “Development, Optimization and Evaluation
of a Polyherbal Formulation for Anti-diabetic Activity” under
the guidance of Dr. Sanjeev Acharya.