prpject re 1

8/8/2019 Prpject Re 1

http://slidepdf.com/reader/full/prpject-re-1 1/32

1

“U need it, we have it”



RESEARCH REPORT OF

“HAIR CARE”

By Pharmacists:

FARAH DAUD

MAHUM SAJID (03345062677)

HIRA SALEEM

SEHAR RASUL

SAADIA MANSUR

Dr. AHSAN SHAH

Dr. MADIHA MALIK

2



Intense heat and humidity can also accelerate oil production. First, it is important to remember

that the hair produces no sebum,. People who complain of oily hair are actually

complaining of an oily scalp. The hair simply wicks the oil away from the scalp. Straighthair moves the oil quickly away from the scalp while tightly kinked hair moves the sebum

very slowly away from the scalp. This explains why Asian persons with very straight hair

note their hair is “oily” while African American persons more commonly note their hair isdry. (3)

.FACTORS

Several factors can be responsible, including,

• Hormonal fluctuations: In adult women, it may come with the menstrual cycle or using

birth control pills. In teens, it's just part of the ever-embarrassing teenaged experience -- oily

hair, zits, the works. When the hormones simmer down, the problem usually evens out.

• Bulking up: Excessive oil is a side effect of using androgenic hormones to increase body

mass. Androgen, a male hormone, can activate the sebaceous glands. Stress boosts

bloodstream levels of androgen in women as well as in men.

• Hair texture: Fine hair is often oilier than coarse hair because it takes up less room on

the scalp. This means people with fine hair are usually crowned with lots more of it than

people with coarse hair. And the more hair there is, the more oil because each follicle issupplied with two to three oil glands.

• Oily hair often linked to genetics: Many hair experts believe that the cause of greasy hair is

hereditary. Yes, it is believed to be genetic. The same hair experts do not believe that it's possible to retard the production of oil and grease delivered to the strands through changes in

diet. During puberty there is a significant marked change in sebum production due to higher

levels of hormones. This why teenagers may go through periods when their hair may becomemore greasy and need to be washed more often. Inadequate removal of the grease makes the

problem worse. (4, 5)

PANEL OF ADVICE

• David Daines is owner of the David Daines Salon in New York City.

• Lowell Goldsmith, M.D., is professor of dermatology and chairman of the Department of

Dermatology at the University of Rochester School of Medicine and Dentistry in New York.He specializes in hair disorders.

• Thomas Goodman, Jr., M.D., is a dermatologist in private practice and assistant professor

of dermatology at the University of Tennessee Center for Health Sciences in Memphis. He is

author of Smart Face and The Skin Doctor's Skin Doctoring Book.

5



• Philip Kingsley is a trained trichologist (hair care specialist) who maintains salons in New

York City and London. He is author of The Complete Hair Book (6).

TREATMENT OF OILY HAIR

First of all, use a special shampoo designed for greasy hair, or a very gentle one with a neutral pH. That way you can wash your hair as much as you want and as soon as you feel the need to,

without worrying about aggravating it.

Properties of an ideal shampoo: The ideal shampoo is always gentle in action, thorough in

dissolving the grime and at the same time, not harsh like a detergent shampoo.

MASSAGE OF HAIR: Massaging hair and scalp is important for the wellbeing as well as good

growth of the hair. For dry hair, scalp massaging with oil is recommended. For oily hair,

massage with toning lotion is suitable. A two minute brushing, stroking and combing routine is

sufficient massage exercise for the scalp.

Oily Hair Home Cure: shampoo cleanser recipe

1. Buy some shikakai powder from the market, some green grams and fenugreek (methi) seeds.

Mix two portions of shikakai powder, one portion of green gram flour and half portion of

Fenugreek powder and keep it in a jar. When required, mix a tablespoon of this mixture in thewhite of an egg and use it as a shampoo. It does not lather like a soap, or shampoo, but cleanses

the hair.

2. Take some dry soap nuts (reetha) and soak them in water overnight. Mash them in themorning and strain the soapy solution. Add a teaspoon of shikakai powder and wash your hair.

(7)

Oily Hair Home Remedy: a mint infusion recipe

If you are unable to make the shampoo cleanser at home, use this infusion recipe. Prepare it andmix it in the shampoo you use. To make the infusion, boil two handfuls of mint (pudina) in one-

and-a-half glass of water for 20 minutes. Strain the solution and mix in a 300 mL bottle of

shampoo.

Oily Hair Treatment: the toning lotion

Mix a tablespoon of Malt Vinegar in a glass of water. Add a pinch of salt in it. Dab two

tablespoons of it on your scalp and massage it with your finger tips twice a week. Leave thelotion on for one hour. Rinse with cool water, brush and set your hair.

The key to controlling greasy hair is to remove the sebum adequately from the scalp. Many

persons mistakenly think that hair shampoo is to wash the hair and not the scalp. Actually,

shampoo is designed to clean the scalp and beautify the hair. Thus, the first recommendation is to

6

http://www.sofeminine.co.uk/guide/beauty/f7455-shampooing-your-hair.html

http://www.sofeminine.co.uk/guide/beauty/f7455-shampooing-your-hair.html



shampoo the scalp. Women with long hair should apply the shampoo to the scalp without piling

the hair on top, and use their fingers to vigorously massage the scalp. (8)

HERBAL / HOMEOPATHIC AND NATURAL REMEDIES FOR OILY HAIR AND

SEBUM

• SAW PALMETTO EXTRACT

• SAW palmetto berry extract helps to balance hormones in boys and chaste tree berry(vitex) helps restore female balance. Seaweed (hizike, kelp, arame) is exceptionally high

in minerals and is considered one of the best foods for nourishing the endocrine glands.

• HERBS: Herbs that can strengthen and cleanse the liver include burdock root dandelion

root, nettle leaf, oregon grape root, and yellow dock root. Herbs work gently and build

up in your system over time if allowed at least 3-4 weeks of consistent use.

• ROLE OF DIET: Studies suggest that people eating a Mediterranean diet, low in

animal fat (saturated fats) and high in olive oil have a lower risk of oily skin. Foods thatare important to add to the diet are fresh fruits and vegetables, particularly those rich in

vitamin A carotene - dark green leafy vegetables, and yellow-orange vegetables and fruits

(apricots, mangoes, carrots, sweet potatoes, yams and squash). Cod liver oil is important

and also contains a lot of vitamin A.

• WATER: It’s also beneficial to drink plenty of purified water (up to 4 quarts of water a

day) to flush out toxins and transport nutrients.

Cedarwood, Virginian ( Juniperus virginiana)

Properties: The two types of cedarwood (Atlas and Virginian) are antiseptic, astringent,

diuretic, sedative (to nervous system) and tonic (to circulatory system).

Usage: It's good for massage, if added to bathwater or a vaporiser/ burner, steam

inhalation; it will affect eczema, oily skin and acne, coughs, bronchitis, catarrh, cystitis,

stress and tension, hair loss and dandruff.

Clary sage ( Salvia sclarea)

Properties: Anti-depressant and soothing, which makes it ideal in treating stress-relateddisorders and depression. Also antiseptic, antibacterial, astringent, deodorant, digestive

and an aphrodisiac. Good for Hair loss, dandruff and oily scalp. (9)

The PHYTO Solution

To help combat oily scalp problems, PHYTO offers products targeting several differentfactors. Minimizing the size of pores in order to reduce sebum production with astringent

plant decoctions (Nettle, Tormentil, Comfrey, Burdock, etc.). Slowing down sebum

migration along the hair shaft by coating it with an amino acid (Lysine) andhelping regulate sebaceous glands with essential oils and sulfur-rich compounds.

7



All PHYTO shampoos contain a mild washing base (Saponaria and Panama Bark

decoction) intended to prevent excess stimulation of the sebaceous glands. To optimize

the action of PHYTO products, avoid excessively energetic massaging, scorching hotwater or violent blow-drying. Remember to use only mild products that will not cause

further reactive secretions. (10)

AIMS AND OBJECTIVES

RATIONALE OF STUDY

Our herbal De-Oleo Shampoo is no ordinary shampoo, and no other shampoo has the same

amount of fresh active extracts in its formula to compete with this. It not only cleanses the

hair properly, but also provides the ingredients to maximize the health and appearance of your hair, while also caring for the condition of your scalp and hair follicles.

Our Herbal De-Oleo Shampoo is one of the finest and best shampoo's ever formulatedwhich makes it a high quality product. The target market for our shampoo is ordinary person

who will be able to afford such a high quality product in a reasonable price. That’s why wekept the price of this shampoo a bit low.

The shampoo will leave your scalp feeling clean and cared for, while at the same time

cleaning and ridding your hair of all grime, pollution, excess oil and dirt, without causing

your hair to look fly-about or splitting the ends of the hair.

Hair will have body, bounce and shine after using it, and the ingredients in the shampoo

will help to sort out any scalp problems like dandruff, and prevent any from appearing andat the same time keep your hair feeling and smelling fresh.

After use you will feel the increase in strength of your hair, and it will be far more manageable and easy to

style. But most importantly, everybody around you will notice the health, sheen, shine, bounce and natural beauty of your hair and you will always be confident that your hair looks the best it has ever done.

HYPOTHESIS

1. A newly formulated herbal shampoo named “De – oleo “will be effective in treating oily hair

in 50% of the subjects after a single use.

2. Herbal method treatment is more preferred in general community.

AIMS AND OBJECTIVES

The shampoo has been designed to,

• Reduce oil content and dandruff deposition

• Provide nourishment to hair

• Strengthen the oily hair

• Increase the hair volume

• Get silky black hair

8



STUDY DESIGN

GANT CHART

DATA-BASED GANT CHART

ACTIVITIES FEB MARCH APRIL MAY JUNE

Proposal Development

Questioner DesigningData Collection

Data Analysis

Manufacturing

FORMULATIOM-BASED GANT CHARTACTVITIES MARCH APRIL MAY JUNE

Formulation Design

QC testing & Piloting

Labeling & Packaging

Cost Evaluation

LEAFLET

DEFINITION

Hair that develops a lank, flat, stringy or oily appearance, due to overproduction of sebum by

sebaceous glands, is often referred as "greasy" hair. This type of hair is hard to control, clumpstogether easily and does not hold a style well.

9



CHARACTRISTICS OF OILY HAIR

Greasy hair is directly related to the overproduction of sebum, a waxy type of substance naturally

occurring in the body which is designed to keep hair soft and waterproof. Sebum is produced by

the sebaceous glands. The amount of greasiness that is experienced is directly tied to the amountof oil present on the scalp.

FORMULATION

Reetha ---- ------------------------------ 25.0g

Amla ------------------------------------- 02.5g

Sikakai ----------------------------------- 02.5gAloe Vera ------------------------------ 20.0g

Olive oil -------------------------------- 01.0g

Vinegar (acetic acid) ----------------- 06.0g

Lanolin ---------------------------------- 02.0gCaustic soda --------------------------- 01.0g

Water ---------------------------------- 36.0gMethyl hydroxy benzoate------------ 02.0g

Ceto lauryl sulphate ------------------ 02.0g

MODE OF ACTION

1. Reetha: It cleans the pores and helps in scalp betterment. It also possessessurfactant and foaming properties.

2. Amla: It strengthens the hair and increases hair length by increasing blood

circulation.

3. Sikakai: it increases the production of melanin pigment which is responsible for hair color. It is also known for cleansing properties that combats the build up of

sebum on scalp.

4. Aloe Vera: It blocks the sebaceous gland pores and reduce sebum productionthus helping to reduce oil content in hair. It also balances the pH value and

eczema of scalp and has a moisturizing effect.

5. Olive oil: It with other active ingredients hydrates the hair root and giveselasticity and shine to hair and rejuvenates the hair.

6. Vinegar (acetic acid): Since acetic acid is naturally acidic so it will cut through

the oil and reduces the oil content in scalp.

DOSAGE FORM

Semisolid dosage form

SIDE EFFECTS

Excessive use may cause hair dryness and loss of luster and shine.

10



STORAGE

Store in a cool and dry place.

Keep away from the reach of children.

DIRECTION FOR USE

Massage onto wet hair. Rinse thoroughly and avoid reuse if required.Avoid eye contact.

METHODOLOGY

Procedure

1. First of all, cleaned, washed and dried the apparatus as per SOP (standard operating

procedure).2. Crushed all the solid ingredients in mortar and pastel, including amla, reetha and seekakai,

and pass it through a sieve to get uniform particle size.3. Weighed all the ingredients, carefully.

4. Took 25 g of reetha and 2 g of lanolin in a beaker.

5. Then added 6 g of acetic acid and 18 g of distilled water in it.6. Heated all the ingredients in water bath at 80°C with continuous stirring.

7. Marked this solution as “A”.

8. Then took another beaker and add finely crushed 2.5 g amla and 2.5 g seekakai in it.

9. Added 20 g of aloe Vera and 18 g of distilled water in it.10. Heated all the ingredients in water bath at 80°C with continuous mixing.

11. Marked it as solution “B”.12. Mixed both the solutions with constant stirring.13. Then added 1 g of caustic soda and 1 g of olive oil in it.

14. Marked it as solution “C”.

15. Then added 2 g of methyl hydroxy benzoate in 2 g of Ceto-lauryl sulphate, withsmall quantity of water, in a beaker and heat it with continuous mixing.

16. When a foamy solution is obtained, removed the beaker from flame and marked this

solution as “D”.17. Solution D was added to solution C and was not stir much and rested the solution

for few minutes.

18, Few drops of orange oil were added to give fragrance.

19. Finally, poured the shampoo in a well-closed container and properly labeled.

STUDY DESIGN

Sample size

A sample size of 55 subjects was selected for data collection through questionnaire. And a group

of six people was usually selected for piloting of the prepared formulation.11



Time Span

Time duration of 10 to 15 days was selected for piloting.

Type of Data

Data was collected by filling questionnaires and through in depth interviews along with directobservation.

Q.C TESTING

Q.C TEST OBSERVATION INFERENCE

pH test:

10-dilution solution pH is

measured by pH meter.

5.6 pH is toward acidic side so it caeasily cut off oil, as oil belong t

lipid class. So pH is ideal.

Sensitivity test:

It is tested by ‘patch test’. Apply

product on 1cm patch of skin, if there is no inflammation or rashes

then it is considered free from

sensitivity.

No Do not cause harm to sensitive

scalp.

Irritation test:

It is carried out by applying

product on the skin for 10minutes. If no irritation occurs

then it is considered as a non-

irritating product.

No Do not cause any redness.

Grittiness:

A pihch of product is rubbed onthe skin and then observed with

magnifying glass;if it is free from

rashes or eruption then it isconsidered as free from grittiness.

Yes As it contains natural herbs whi

are not in fine form.

Microbial growth:

It is tested by microbial assay

method as per the specification

given pharmacopoeia.

No No preservative is added, still nomicrobial growth.

STABILITY TESTING

As the product has been formulated in April. Stability testing will be carried out till

October at different temperature and humidity condition. pH will also be monitor.

12



PILOTING AND RESULTS

METHOD OF PILOTING

A sample size of six people is selected we have to apply ‘t-test. Precondition of the persons inthe group is monitored and recorded. The formulation whose QC test are confirmed is then

applied for certain time period(usually for one week) to check it monitored effect. After the

designated period, the post condition results are monitored and recorded.

Both the results of pre and post condition are compared and analyzed statistical by applying ‘t-

test

Before application: Indicator Scale

1 – 5 : Very oily hair 6 –10 : Moderately oily11 - 15 : Less oily

After application:Indicator Scale

1 – 5 : Completely satisfied6 –10 : Partially satisfied

11 - 15 : Not satisfied

13



Subject Before

application

Indicator scale After

application

Indicator scale

1 My hair were

oily and sticky

2 Now after 2-3

times of usage,I felt a greatchange.

10

2 I never feel

good withoutlook of my

hair, I cannot

make anyhairstyle.

5 Now after

usage I can tryany hair style.

8

3 My oily after every 1-2 days

which reallyhair use to getupsets me.

8 Now after usage, my hair

have becomereally shiny

3

4 My family and

my friends usedto make fun of

my oily hair. I

always getembarrassed

12 It feels great

now after itsusage and they

are the one who

praise them.

3

5 My hair wereoily

3 Improvement isseen but not

much.

10

6 My hair get oilyafter every 1-2

days

2 Now after usage my hair

have become

really shiny.

10

14



STATISTICAL ANALYSIS

OBSERVATIONS BEFORE APPLICATION:

Indicator Scale

1 – 5 : Very oily hair

6 –10 : Moderately oily11 - 15 : Less oily

SUBJECT

n=6

INDICATOR

SCALE

MEAN

(M1)

DEVIATION

(d)

d2 STANDARD

DEVIATION

(S.D1)

STANDARD

ERROR

(S.E1)

1 2 5.33 -3.33 11 d2= 78.6

n-1 6-1

= 78.65

= 15.72

= 3.96

S.D= 3.96

n 6

= 3.962.45

= 1.6

2 5 -0.33 0.1

3 8 2.67 7.14 12 7.33 44

5 3 -2.33 5.4

6 2 -3.33 11

OBSERVATIONS AFTER APPLICATION:

Indicator Scale

1 – 5 : Completely satisfied6 –10 : Partially satisfied

11 - 15 : Not satisfied

SUBJECT INDICATOR

SCALE

MEAN

(M2)

DEVIATION

(d)

D2 STANDARD

DEVIATION

(S.D2)

STANDARD

ERROR

(S.E2)

1 10 7.33 2.67 7.13 d2= 59.34

n-1 6-1

= 59.34

5

=11.868

= 3.4

S.D= 3.4

n 6

= 3.4

2.45

= 1.38

2 8 0.67 0.45

3 3 -4.33 18.75

4 3 -4.33 18.75

5 10 2.67 7.13

6 10 2.67 7.13

CALCULATIONS:15



*Applying t-test: M2-M1

(S.E1)2+(S.E2)

2

= 7.33-5.33

(1.6)2+(1.38)2

= 2/4.46

= 2/2.1= 0.95

*Degree of freedom: n-1

= 6-1

= 5

*Value of alpha from table for 5% probability value: 2.57

RESULTS:Since the result for t-test, 0.95, is less than probability value, 2.57, it indicates that the new

herbal formulation is efficacious up to 95%.

SPSS RESULTS

Frequency Table

Gender

Frequency Percent

Valid

Percent

Cumulative

Percent

Valid Male 17 30.9 30.9 30.9Female 38 69.1 69.1 100.0

Total 55 100.0 100.0

Age

Frequency Percent

Valid

Percent

Cumulative

Percent

Valid 15-20 11 20.0 20.0 20.0

20-25 21 38.2 38.2 58.2

25-30 7 12.7 12.7 70.9

30-35 11 20.0 20.0 90.9

Above 5 9.1 9.1 100.0

Total 55 100.0 100.0

16



Occupation

Frequency Percent

Valid

Percent

Cumulative

PercentValid Student 30 54.5 54.5 54.5

Professional 14 25.5 25.5 80.0

House wife 11 20.0 20.0 100.0

Total 55 100.0 100.0

Socio-economic status

Frequency Percent

Valid

Percent

Cumulative

Percent

Valid Middle 45 81.8 81.8 81.8

High 10 18.2 18.2 100.0

Total 55 100.0 100.0

Hair texture

Frequency Percent

Valid

Percent

Cumulative

Percent

Valid Oily 55 100.0 100.0 100.0

Normal practice

Frequency Percent

Valid

Percent

Cumulative

Percent

Valid Soap 4 7.3 7.3 7.3Shampoo 51 92.7 92.7 100.0

Total 55 100.0 100.0

17



Nature of product in use

Frequency Percent

Valid

Percent

Cumulative

Percent

Valid Medicated 10 18.2 18.2 18.2

Non-medicated 45 81.8 81.8 100.0

Total 55 100.0 100.0

Need for hair wash

Frequency Percent

Valid

Percent

Cumulative

Percent

Valid After 2

days

45 81.8 81.8 81.8

After 4

days

10 18.2 18.2 100.0

Total 55 100.0 100.0

Esthetic appeal

Frequency Percent

Valid

Percent

Cumulative

Percent

Valid Yes 46 83.6 83.6 83.6

No 9 16.4 16.4 100.0

Total 55 100.0 100.0

Personal experience for hair treatment

Frequency Percent

Valid

Percent

Cumulative

Percent

Valid Homeopathic 4 7.3 7.3 7.3

Allopathic 3 5.5 5.5 12.7

Indigenous 7 12.7 12.7 25.5

Never have any

treatment

41 74.5 74.5 100.0

Total 55 100.0 100.0

18



New experience

Frequency Percent

Valid

Percent

Cumulative

Percent

Valid Yes 49 89.1 89.1 89.1 No 1 1.8 1.8 90.9

Why

not

5 9.1 9.1 100.0

Total 55 100.0 100.0

BAR CHART

19



20



21



22



23



24



25



26



27



28



29



PACKAGING AND LAUNCHING

PACKAGING:

• PRIMARY PACKAGING:

A plastic bottle is used to pack the contents. .

• SECONDARY PACKAGING:

A cardboard box is used to pack the formulation so as to protect the bottle from cracking.

LABELLING:

BATCH NUMBER:

REGISTRATION

NUMBER:

LISCENCE NUMBER:

MFG. DATE:

EXP. DATE:

M.R.P:

DE – OLEO

(Shampoo for oily hair)

100g

COMPOSITION:

Reetha

Amla

Sikakai

Aloe Vera

Olive oil

Vinegar(acetic acid)

PRECAUTIONS:For external use only.

Avoid contact with eyes.

Keep in cool & dry place.

Ensure that cap is tightly

closed.

30



DISCUSSION

DISCUSSION:

1. Out of total targeted community, 31% were males and 69% were females.

2. 20% belonged to age group ranging from 15-20 years, 38% from age group 20-25 years,

12% from age group 25-30 years, 20% from age group 30-35 years and 10% from agegroup above 35 years.

3. Around 55% of total targeted people were students, 25% were professionals and 20%

were house wives, by profession.

4. 82% middle class and 18% elite class was targeted.5. As only people with oily hair texture were interviewed thus percentage is 100%.

6. Only 7% people use soaps for hair wash. 93% use shampoos.

7. 82% people use non-medicated product and only 18% people use medicated product for

oily hair.8. 82% people find need for hair wash after 2 days and 18% wash their hair after 4 days.

9. 84% people feel that oily hair affects their appearance while a 16% person doesn’t think like this.

10. As personal experience for hair treatment, only 7% people rely upon homeopathic

products, 6% upon allopathic products, 12% use indigenous products while major portion

i.e. of 75% has never had any treatment.11. Around 89% people were willing to try a new herbal product to treat oily hair while 2%

were not. 9% people were having different issues in using any new product.

IMPLICATIONS

• De-OLEO Shampoo contains no "flash-foamers", foaming chemicals that add lather (which

does nothing for the hair) and damages the hair shafts and the scalp.

• It is a superb shampoo and contains no harsh chemicals, yet is ultra effective.

• Not only will it remove all grime, pollution, excess oil and dirt from the hair, it

conditions it at the same time.

• All the herbal ingredients work in synergy to stimulate hair growth and to maximize the

health of your hair.

• Hair has more body, bounce and shine when using it.

• Prevents and sorts scalp problems such as dandruff etc.

• Hair will be more manageable and easy to style.

31



REFRENCES

1. Karen Marie Shelton - Copyright 1998 Revised Date: 01/01/08 - Original Publication Date:

03/01/1998.2. Mother nature.com.

3. Mother nature.com

4. Karen Marie Shelton - Copyright 1998 Revised Date: 01/01/08 - Original Publication Date:

03/01/1998.5. Karen Marie Shelton - Copyright 1998 Revised Date: 01/01/08 - Original Publication Date:

03/01/1998.

6. www.medicine online.com

7. Mother nature.com

8. http://www.home-remedies-for-you.com

9. www.bbc.co.uk/health/healthy_living/complementary_medicine/remedies_oils.shtml.

10. mp.hair boutique.com/phyto_pg_oily _scalp.asp

11. A study on dehairing Australian greasy cashmere Issue Volume 9, Number 4 / August, 2008

12. International Journal of Cosmetic ScienceVolume 1 Issue 3, Pages 169 - 176 Published Online: 18

May 2007

13. MONIQUE COURTOIS*, PAUL KRIEN**, LUC MEYRONNE* JEAN-FRANÇOIS GROLLIER

Volume 8 Issue 6, Pages 275 - 287 Published Online: 24 May 2007

14. International Journal of Cosmetic ScienceVolume 9 Issue 3, Pages 111 - 124 Published Online: 18

May 2007

15. www.ijp-online.com

32

http://www.medicine/

http://www.home-remedies-for-you.com/

http://www.bbc.co.uk/health/healthy_living/complementary_medicine/remedies_oils.shtml

http://www.springerlink.com/content/p64567v51h83/?p=9ec6657d59fa4b8fb1f84ef3722db2df&pi=0

http://www3.interscience.wiley.com/journal/117986976/home

http://www3.interscience.wiley.com/journal/120057021/issue




http://www.medicine/

http://www.home-remedies-for-you.com/

http://www.bbc.co.uk/health/healthy_living/complementary_medicine/remedies_oils.shtml

http://www.springerlink.com/content/p64567v51h83/?p=9ec6657d59fa4b8fb1f84ef3722db2df&pi=0






prpject re 1

Documents