Perforin and Granzyme re

leas

ed

Fc receptor

Antibody

Cancer antigen

Make High Quality Affordable

•Protein •Antibody •Gene •ELISA Kit •Cell Lysate

Cancer-Cell

NK-Cell

www.sinobiological.com

Fc receptor Function and Molecules

Function:1, Involved in innate immune system & adaptive immune system2, Activation of phagocytes3, Involved in antibody-dependent cell-mediated cytotoxicity (ADCC)4, Stimulate NK cells to release cytotoxic molecules5, Involved in allergic reactions 6, Defense against parasitic infections.

Application:1, ADCC activity evaluation of therapeutic monoclonal antibody 2, Indicator of allergic reaction test 3, PK/PD analysis of therapeutic monoclonal antibody 4, Drug targets of potential autoimmune disease

All molecules of Fc receptor:Our products cover most of them with multiple species.

In progress

High

High

Putative high

Low

Low

Low

Low

Low

Low

a novel mouse receptor

Low

High

High

High

High

CD89

CD64 / FCGR1A

IGFRB

IGFRC

CD32a

CD32b

CD32c

CD16

CD16a

CD16b

CD16-2

CD23

FCE1A

FCER1B

FCRH1 / CD307a

FCRH2 / CD306b

FCRH3 / CD307c

FCRH4 / CD307d

FCRH5 / CD307e

FCRH6

FCRN

CD351

FCAR

FCGR1

FCGR1B

FCGR1C

FCGR2A

FCGR2B

FCGR2C

FCGR3

FCGR3A

FCGR3B

FCGR4

FCER2

FCER1A

MS4A2

FCER1G

FCRL1

FCRL2

FCRL3

FCRL4

FCRL5

FCRL6

FCRLA

FCRLB

FCGRT

FCAMR

IgG Fc receptor IV

IgE Fc Receptor

FCRL

IgG receptor

IgG & IgM receptor

IgA Fc Receptor

IgG FcReceptor

IgG Fc receptor I

IgG Fc receptor II

IgG Fc receptor III

Molecule Alias Binding affinity to Ig Products In SinoType

Make High Quality Affordable

Fc receptor Recombinant Protein

Molecule Product Name Species Expressed Host Bio-activity10414-H08H

80014-R08H

50086-M08H

50086-M27H

50086-M27H-B

80016-R08H

10374-H08H

10374-H08B

10374-H02H

10374-H08H1

10374-H27H1

10374-H27H

90015-C08H

90015-C27H

10374-H27H1-B

10374-H27H-B

90015-C27H-B

90016-C08H

10374-H08C

10374-H08C1

10259-H08H

Catalog No.FCAR

FCAR

FCGR1

FCGR1

FCGR1

FCGR1

FCGR2A

FCGR2A

FCGR2A

FCGR2A

FCGR2A

FCGR2A

FCGR2A

FCGR2A

FCGR2A

FCGR2A

FCGR2A

FCGR2A

FCGR2A

FCGR2A

FCGR2B

Human CD89 / FCAR Protein (His Tag)

Rat CD89 / FCAR Protein (His Tag)

Mouse CD64 / FCGR1 Protein (His Tag)

Mouse CD64 / FCGR1 Protein (His & AVI Tag)

Mouse CD64 / FCGR1 Protein (His & AVI Tag), Biotinylated

Rat CD64 / FCGR1A Protein (His Tag)

Human CD32a / FCGR2A Protein (167 Arg, His Tag)

Human CD32a / FCGR2A Protein (166 Arg, His Tag)

Human CD32a / FCGR2A Protein (167 Arg, Fc Tag)

Human CD32a / FCGR2A Protein (167 His, His Tag)

Human CD32a / FCGR2A Protein (167 His) (His & AVI Tag)

Human CD32a / FCGR2A Protein (167 Arg) (His & AVI Tag)

Cynomolgus CD32a / FCGR2A Protein (His Tag)

Cynomolgus CD32a / FCGR2A Protein (His & AVI Tag)

Human CD32a / FCGR2A Protein (167 His, His & AVI Tag), Biotinylated

Human CD32a / FCGR2A Protein (167 Arg, His & AVI Tag), Biotinylated

Cynomolgus CD32a / FCGR2A Protein (His & AVI Tag), Biotinylated

Cynomolgus CD32a / FCGR2A Protein (His Tag)

Human CD32a / FCGR2A Protein (167 Arg, His Tag)

Human CD32a / FCGR2A Protein (167 His, His Tag)

Human CD32b / FCGR2B Protein (His Tag)

Human

Rat

Mouse

Mouse

Mouse

Rat

Human

Human

Human

Human

Human

Human

Cynomolgus

Cynomolgus

Human

Human

Cynomolgus

Cynomolgus

Human

Human

Human

Human Cells

Human Cells

Human Cells

Human Cells

Human Cells

Human Cells

Human Cells

Baculovirus-Insect Cells

Human Cells

Human Cells

Human Cells

Human Cells

Human Cells

Human Cells

Human Cells

Human Cells

Human Cells

Human Cells

Human Cells

CHO Cells

CHO Cells

OD4

50nm

-B

human IgG1/BiotinCon.(ug/ml) FCGR2A / CD32a (Cat: 10374-H08B) binds to recombinant human IgG1

0

1

2

3

4

5

1E-4 1E-3 0.01 0.1 1 10

R: Activity of binding to immunoglobulinHigh purity1 Mutiple species2 High Bingding activity3

Recombinant Protein list:

0.0

0.5

1.0

1.5

2.0

2.5

3.0

OD4

50nm

-B

SCT630 Con(ug/ml)1010.1

FCGRT & B2M (Cat:CT009-H08H) binds to recombinant human IgG1

0

1

2

3

4

5

human IgG1/Biotin Con.(ug/ml)

1E-4 1E-3 0.01 0.1 1 10

OD

450n

m-B

FCGR2B / CD32b (Cat: 10259-H08H) binds to recombinant human IgG1

Human Mouse Cynomolgus Rat

Protein（W: wild M: mutant）MoleculeFCARFCGR1FCGR2A

FCGR2BFCGR3FCGR3A

FCGR3BFCGR4FCER2FCER1AFCRL1FCGRT & B2M

(W)

(W)(M: 167Arg, 167His)

(W)

(W)(M: 176Phe, 176Val)

(W)

(W) (W) (W) (W) (W)

(W) (W) (W)

(W)

(W)

(W)

(W)

(W) (W)

(W)

(W)

(W)

(W)

(W)

(W)

(W)

Fc receptor Recombinant Protein

Recombinant Protein list:

Catalog No. Bio-activity

FCGR3A / CD16a (Cat:10389-H27H1) binds to recombinant human IgG1

1E-3 0.01 0.1 1 10

0

1

2

3

4

5

human IgG1/Biotin Con.(ug/ml)

OD4

50nm

-BBiotinylatedBiotinylated

10259-H08H90014-C08H90014-C27H10259-H27H10259-H27H-B90014-C27H-B80018-R08H10259-H08C11046-H08H50326-M08H90013-C27H90013-C08H90013-C27H-B10389-H08H10389-H08H110389-H27H10389-H27H110389-H27H1-B10389-H27H-B80017-R08H10389-H08C110389-H08C11046-HNAE11046-H08C50036-M08H50036-M27H50036-M27H-B50695-M07H10261-H07H80208-R01H13193-H08H50935-M02H11536-H08H50947-M08HCT009-H08HCT029-M08HCT030-R08HCT031-C08H

FCGR4FCGR4FCER2FCER2FCER2FCER1AFCER1AFCRL1FCRL1FCGRT & B2MFCGRT & B2MFCGRT & B2MFCGRT & B2M

FCGR3FCGR3FCGR3FCGR3FCGR3AFCGR3AFCGR3AFCGR3A

FCGR3AFCGR3AFCGR3AFCGR3AFCGR3BFCGR3BFCGR4

FCGR3A

FCGR2BFCGR2BFCGR2BFCGR2BFCGR2BFCGR2BFCGR2BFCGR2BFCGR3B

Molecule

Human CD32b / FCGR2B Protein (His Tag)Cynomolgus CD32b / FCGR2B Protein (His Tag)Cynomolgus CD32b / FCGR2B Protein (His & AVI Tag)Human CD32b / FCGR2B Protein (His & AVI Tag)Human CD32b / FCGR2B Protein (His & AVI Tag), BiotinylatedCynomolgus CD32b / FCGR2B Protein (His & AVI Tag), BiotinylatedRat CD32b / FCGR2B Protein (His Tag)Human CD32b / FCGR2B Protein (His Tag)Human CD16b / FCGR3B Protein (His Tag)Mouse CD16 / FCGR3 Protein (His Tag)Cynomolgus CD16 / FCGR3 Protein (His & AVI Tag)Cynomolgus CD16 / FCGR3 Protein (His Tag)Cynomolgus CD16 / FCGR3 Protein (His & AVI Tag), BiotinylatedHuman CD16a / FCGR3A Protein (176 Phe, His Tag)Human CD16a / FCGR3A Protein (176 Val, His Tag)Human CD16a / FCGR3A Protein (176 Phe) (His & AVI Tag)Human CD16a / FCGR3A Protein (176 Val) (His & AVI Tag)Human CD16a / FCGR3A Protein (176 Val, His & AVI Tag), Human CD16a / FCGR3A Protein (176 Phe, His & AVI Tag), Rat CD16a / FCGR3A Protein (His Tag)Human CD16a / FCGR3A Protein (176 Val, His Tag)Human CD16a / FCGR3A Protein (His Tag)Human CD16b / FCGR3B ProteinHuman CD16b / FCGR3B Protein (His Tag)Mouse CD16-2 / FCGR4 Protein (His Tag)Mouse CD16-2 / FCGR4 Protein (His & AVI Tag)Mouse CD16-2 / FCGR4 Protein (His & AVI Tag), BiotinylatedMouse CD23 / FCER2 Protein (His Tag)Human CD23 / FCER2 Protein (His Tag)Rat CD23 / FCER2 / FCER2A Protein (Fc Tag)Human FcERI / FCER1A Protein (His Tag)Mouse FcERI / FCER1A Protein (Fc Tag)Human FCRL1 / FCRH1 Protein (His Tag)Mouse FCRL1 / FCRH1 Protein (His Tag)Human FCGRT & B2M Heterodimer ProteinMouse FCGRT & B2M Heterodimer ProteinRat FCGRT & B2M Heterodimer ProteinCynomolgus FCGRT & B2M Heterodimer Protein

Product Name

HumanCynomolgusCynomolgusHumanHumanCynomolgusRatHumanHumanMouseCynomolgusCynomolgusCynomolgusHumanHumanHumanHumanHuman

RatHumanHumanHumanHumanMouseMouseMouseMouseHumanRatHumanMouseHumanMouse

Human

HumanMouseRatCynomolgus

Species

Human CellsHuman CellsHuman CellsHuman CellsHuman CellsHuman CellsHuman CellsCHO CellsHuman CellsHuman CellsHuman CellsHuman CellsHuman CellsHuman CellsHuman CellsHuman CellsHuman CellsHuman CellsHuman CellsHuman CellsCHO CellsCHO CellsE. coliCHO CellsHuman CellsHuman CellsHuman CellsHuman CellsHuman CellsHuman CellsHuman CellsHuman CellsHuman CellsHuman CellsHuman CellsHuman CellsHuman CellsHuman Cells

Expressed Host

1E-3 0.01 0.1 1 10

0

1

2

3

4

FCGR3A / CD16a (Cat: 10389-H08H1) binds to recombinant human IgG1

human IgG1 Con.(ug/ml)

OD4

50nm

-B

www.sinobiological.com

Make High Quality Affordable

Fc receptor Antibody

•Multiple applications•Multiple antibody types•High affinity & sensitivity

Flow cytometric analysis of anti-human FCAR / CD89 antibody on human whole blood monocytes (10414-MM02-P)

AntibodyMoleculeFCARFCGR1FCGR2AFCGR2BFCGR3FCGR3AFCGR3BFCGR4FCER2FCER1AFCRL1FCGRT & B2M

ELISA, FCMWB, ELISA, ELISA, IHC-PELISAELISAWB, ELISAWB, ELISA,

ELISA, IHC-P

ELISA

Mouse MAbELISAELISA, FCM, WB, ELISA, ELISA, IHC-P, ELISA

ELISA, ICC/IF, ELISA

Rabbit MAbELISAELISAELISAELISA, IHC-PELISAELISAELISAELISAELISA

ELISAELISA, IHC-P

Rabbit PAb

Purified

Purified

Purified

Purified

Human

HumanHumanHumanHumanRat

RatHumanHuman

HumanHumanMouse

MouseMouseMouseMouse

Human

Rat

Human

Mouse

Rat

Antigen Species

FCAR

FCARFCARFCARFCARFCAR

FCARFCGR1FCGR1

FCGR1FCGR1FCGR1

FCGR1FCGR1FCGR1FCGR1FCGR1

FCAR

FCAR

FCGR1

FCGR1

Molecule

CD89 / FCAR Antibody, Rabbit PAb

CD89 / FCAR Antibody, Mouse MAbCD89 / FCAR Antibody, Rabbit MAbCD89 / FCAR Antibody (FITC), Mouse MAbCD89 / FCAR Antibody (PE), Mouse MAbCD89 / FCAR Antibody, Rabbit PAb

CD89 / FCAR Antibody, Rabbit MAbCD64 / FCGR1A Antibody, Mouse MAbCD64 / FCGR1 Antibody, Rabbit PAb

CD64 / FCGR1 Antibody (FITC), Mouse MAbCD64 / FCGR1 Antibody (PE), Mouse MAbCD64 / FCGR1 Antibody, Rabbit PAb

CD64 / FCGR1 Antibody, Rabbit MAbCD64 / FCGR1 Antibody (FITC), Rabbit MAbCD64 / FCGR1 Antibody (PE), Rabbit MAbCD64 / FCGR1 Antibody, Rabbit MAbCD64 / FCGR1A Antibody, Rabbit PAb, Antigen Affinity

CD89 / FCAR Antibody, Rabbit PAb, Antigen Affinity

CD89 / FCAR Antibody, Rabbit PAb, Antigen Affinity

CD64 / FCGR1 Antibody, Rabbit PAb, Antigen Affinity

CD64 / FCGR1 Antibody, Rabbit PAb, Antigen Affinity

Product Name

Rabbit PAbRabbit PAbMouse MAbRabbit MAbMouse MAbMouse MAbRabbit PAbRabbit PAbRabbit MAbMouse MAbRabbit PAbRabbit PAbMouse MabMouse MabRabbit PAbRabbit PAbRabbit MAbRabbit MAbRabbit MAbRabbit MAbRabbit PAb

Ab type

50086-R027-F50086-R027-P50086-R00880016-RP02

10256-MM0610256-RP01

10256-MM09-F10256-MM09-P50086-RP01

50086-R001

10256-RP02

50086-RP02

10414-R00610414-MM02-F10414-MM02-P80014-RP01

80014-R01380014-RP02

10414-RP01

10414-MM0210414-RP02

Catalog No.

ELISAELISAELISAELISAFCMFCMELISAELISAELISAELISAELISAELISAFCMFCMELISAELISAELISA, IHC-PFCMFCMELISA, IHC-PELISA

Application

Anti-Fc receptor Antibody list:

Detection of FCGR1 / CD64 in mouse liver by immunohistochemistry

(50086-R008)

Detection of FCGR2B / CD32b in human lymphonode by immunohistochemistry

(10259-R110)

Fc receptor Antibody

Purified

Purified

FCM, IF

Purified

Detection of Human FCER2 / CD23 in human tonsil by immunohistochemistry

(10261-MM05)

Detection of Mouse FCGR4 / CD16-2 in RAW264.7 cells by immunofluorescence

(50036-R012)

Catalog No. Antigen Species Molecule Product Name Ab type Application80016-MM0180016-R01510374-MM0110374-MM0210374-MM0310374-RP0110374-RP0210374-R02090015-RP0290016-RP0290015-MM0690016-MM0190016-R14810259-RP0110259-MM0210259-RP0310259-R11210259-R11090014-RP0290014-MM0390014-R04680018-RP0180018-RP0290013-RP0290013-MM0150326-RP0150326-RP0250326-R01510389-MM0210389-MM0310389-RP0110389-RP0280017-RP0280017-MM0611046-RP0111046-RP0211046-MM0111046-MM0750036-RP0150036-RP0250036-R01250036-R012-F50036-R01150695-RP0150695-RP0210261-MM0510261-R17650695-R01111536-RP02CT009-RP02CT009-RP01

RatRatHumanHumanHumanHumanHumanHumanCynomolgusCynomolgusCynomolgusCynomolgusCynomolgusHumanHumanHumanHumanHumanCynomolgusCynomolgusCynomolgusRatRatCynomolgusCynomolgusMouseMouseMouseHumanHumanHumanHumanRatRatHumanHumanHumanHumanMouseMouseMouseMouseMouseMouseMouseHumanHumanMouseHumanHumanHuman

FCGR1FCGR1FCGR2AFCGR2AFCGR2AFCGR2AFCGR2AFCGR2AFCGR2AFCGR2AFCGR2AFCGR2AFCGR2AFCGR2BFCGR2BFCGR2BFCGR2BFCGR2BFCGR2BFCGR2BFCGR2BFCGR2BFCGR2BFCGR3FCGR3FCGR3FCGR3FCGR3FCGR3AFCGR3AFCGR3AFCGR3AFCGR3AFCGR3AFCGR3BFCGR3BFCGR3BFCGR3BFCGR4FCGR4FCGR4FCGR4FCGR4FCER2FCER2FCER2FCER2FCER2FCRL1FCGRT & B2MFCGRT & B2M

CD64 / FCGR1A Antibody, Mouse MAbCD64 / FCGR1A Antibody, Rabbit MAbCD32a / FCGR2A Antibody, Mouse MAbCD32a / FCGR2A Antibody, Mouse MAbCD32a / Fc gamma RIIA Antibody, Mouse MAbCD32a / Fc gamma RIIA Antibody, Rabbit PAbCD32a / Fc gamma RIIA Antibody, Rabbit PAb, Antigen Affinity PurifiedCD32a / FCGR2A Antibody, Rabbit MAbCD32a / Fc gamma RIIA Antibody, Rabbit PAb, Antigen Affinity PurifiedCD32a / Fc gamma RIIA / FCGR2A Antibody, Rabbit PAb, Antigen Affinity CD32a / Fc gamma RIIA Antibody, Mouse MAbCD32a / Fc gamma RIIA / FCGR2A Antibody, Mouse MAbCD32a / Fc gamma RIIA / FCGR2A Antibody, Rabbit MAbCD32b / FCGR2B Antibody, Rabbit PAbCD32b / FCGR2B Antibody, Mouse MAbCD32b / FCGR2B Antibody, Rabbit PAb, Antigen Affinity PurifiedCD32b / FCGR2B Antibody, Rabbit MAbCD32b / FCGR2B Antibody, Rabbit MAbCD32b / Fc gamma RIIB Antibody, Rabbit PAb, Antigen Affinity PurifiedCD32b / Fc gamma RIIB Antibody, Mouse MAbCD32b / Fc gamma RIIB Antibody, Rabbit MAbCD32b / Fc gamma RIIB / FCGR2B Antibody, Rabbit PAbCD32b / Fc gamma RIIB / FCGR2B Antibody, Rabbit PAb, Antigen Affinity CD16 / FCGR3 Antibody, Rabbit PAb, Antigen Affinity PurifiedCD16 / FCGR3 Antibody, Mouse MAbCD16 / FCGR3 Antibody, Rabbit PAbCD16 / FCGR3 Antibody, Rabbit PAb, Antigen Affinity PurifiedCD16 / FCGR3 Antibody, Rabbit MAbCD16a / FCGR3A Antibody, Mouse MAbCD16a / FCGR3A Antibody, Mouse MAbCD16a / FCGR3A Antibody, Rabbit PAbCD16a / FCGR3A Antibody, Rabbit PAb, Antigen Affinity PurifiedCD16a / FCGR3A Antibody, Rabbit PAb, Antigen Affinity PurifiedCD16a / FCGR3A Antibody, Mouse MAbCD16b / FCGR3B Antibody, Rabbit PAbCD16b / FCGR3B Antibody, Rabbit PAb, Antigen Affinity PurifiedCD16b / FCGR3B Antibody, Mouse MAbCD16b / FCGR3B Antibody, Mouse MAbCD16-2 / FCGR4 Antibody, Rabbit PAbCD16-2 / FCGR4 Antibody, Rabbit PAb, Antigen Affinity PurifiedCD16-2 / FCGR4 Antibody, Rabbit MAbCD16-2 / FCGR4 Antibody (FITC), Rabbit MAbCD16-2 / FCGR4 Antibody, Rabbit MAbCD23 / FCER2 Antibody, Rabbit PAbCD23 / FCER2 Antibody, Rabbit PAb, Antigen Affinity PurifiedCD23 / FCER2 Antibody, Mouse MAbCD23 / FCER2 Antibody, Rabbit MAbCD23 / FCER2 Antibody, Rabbit MAbFCRL1 / FCRH1 Antibody, Rabbit PAb, Antigen Affinity PurifiedFCGRT & B2M Heterodimer (FcRn) Antibody, Rabbit PAb, Antigen Affinity FCGRT & B2M Heterodimer Antibody, Rabbit PAb

Mouse MAbRabbit MAbMouse MAbMouse MAbMouse MAbRabbit PAbRabbit PAbRabbit MAbRabbit PAbRabbit PAbMouse MAbMouse MAbRabbit MAbRabbit PAbMouse MAbRabbit PAbRabbit MAbRabbit MAbRabbit PAbMouse MAbRabbit MAbRabbit PAbRabbit PAbRabbit PAbMouse MAbRabbit PAbRabbit PAbRabbit MAbMouse MAbMouse MAbRabbit PAbRabbit PAbRabbit PAbMouse MAbRabbit PAbRabbit PAbMouse MAbMouse MAbRabbit PAbRabbit PAbRabbit MAbRabbit MAbRabbit MAbRabbit PAbRabbit PAbMouse MAbRabbit MAbRabbit MAbRabbit PAbRabbit PAbRabbit PAb

ELISAELISAELISAELISAELISAELISAELISAWBELISAELISAELISAELISAELISAELISAELISAELISAELISAELISA, IHC-P, ELISA, IHC-PELISAELISAWB, ELISAELISA, IHC-PELISAELISAELISAELISAELISAELISAELISAELISAELISAELISAELISAELISAELISAELISAIHC-PELISAELISAELISA, ICC/IF, FCMELISA, IHC-PELISAELISAELISA, IHC-PELISAELISAELISAIHC-PELISA

www.sinobiological.com

Make High Quality Affordable

Gene & ELISA Kit & Cell Lysate

FCARFCGR1FCGR2AFCGR2BFCGR3FCGR3AFCGR3BFCER2FCER1AMS4A2FCER1GFCRL1FCRL3FCRL4FCGRTFCAMR

Human Mouse Rat Cynomolg RabbitGenemolecule

Biotin-conjugate

Target Protein

Capture Antibody

More information:

Products of IgG & IgM:

www.sinobilogical.com/Fc-Receptor-Proteins-a-72.html

www.sinobiological.com/Secondary-Antibody.html

Human CynomolgELISAmolecule

Cell lysatemolecule

Human Mouse Cynomo Rat

FCAR ELISA(HRP) FCGR2A ELISA(HRP) FCGR2B ELISA(HRP,Biotin) FCGR3 ELISA(HRP)

FCARFCGR1FCGR2AFCGR2BFCGR3FCGR3AFCGR3BFCGR4FCER2FCER1AFCRL1FCGRT &

Fc receptor

~23000 Research Reagents

www.sinobiological.com

Contact UsE-mail: order@sinobiological.comTel: +86-400-890-9989Fax: +86-010-5102-9969Website: www.sinobiological.com