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Progress Against Ovarian Cancer

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Page 1: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian

Cancer

Page 2: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

1970–1979

Page 3: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

1970–19791978: First effective combination chemotherapy regimen for ovarian cancer

1978: Cisplatin approved for advanced ovarian cancer

Page 4: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

1980–1989

Page 5: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

1980–19891981: Oral contraceptives found to cut ovarian cancer risk

Page 6: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

1980–1989Mid-1980s: Scientists discover ''biomarker'' tied to ovarian cancer – CA-125

Page 7: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

1980–19891989: FDA approves carboplatin for ovarian cancer

Page 8: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

1990–1999

Page 9: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

1990–19991992–1994: Taxanes emerge as vital chemotherapy option for ovarian, breast cancer

Page 10: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

1990–19991996: New chemotherapy drug for advanced ovarian cancer

Page 11: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

1990–1999Late 1990s: BRCA1 and BRCA2 gene mutations linked to increased ovarian cancer risk

Page 12: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

1990–19991999: FDA approves liposomal doxorubicin for advanced ovarian cancer

Page 13: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

2000–Present

Page 14: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

2000–Present2003: New chemotherapy regimen – docetaxel and paclitaxel – provides important treatment option

Page 15: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

2000–Present2005: Researchers work to decode the ovarian cancer genome

Page 16: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

2000–Present2006: Researchers find some ovarian cancers begin in the fallopian tubes

2006: Direct chemotherapy approach increases survival

Page 17: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

2000–PresentLate 2000s: Researchers identify at least two ovarian cancer subtypes

Page 18: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

2000–Present2009: Preventive surgery confirmed to reduce breast and ovarian cancer risk in women with BRCA gene mutations

Page 19: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

2000–Present2010: Regular CA125 testing to monitor for ovarian cancer recurrence is questioned

2010: Bevacizumab significantly delays progression of advanced ovarian cancer

2010: Pre-surgery chemotherapy proven an effective option for women with advanced ovarian cancer

Page 20: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

Five-Year Survival

34

36

38

40

42

44

46

1975

1977

1979

1981

1983

1985

1987

1989

1991

1993

1995

1997

1999

2001

2003

2005

2007

2009

Year of Diagnosis

% o

f Pa

tien

ts S

urv

ivin

g F

ive

Ye

ars

Source: National Cancer Institute

Page 21: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

Mortality

5

6

7

8

9

10

11

12

13

1970

1972

1974

1976

1978

1980

1982

1984

1986

1988

1990

1992

1994

1996

1998

2000

2002

2004

2006

2008

2010

Year of Death

Ca

nce

r D

ea

ths

pe

r 1

00

,00

0 P

eo

ple

Source: National Cancer Institute

Page 22: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Progress Against Ovarian Cancer

New Cases

11

12

13

14

15

16

17

18

19

1973

1975

1977

1979

1981

1983

1985

1987

1989

1991

1993

1995

1997

1999

2001

2003

2005

2007

2009

Year of Diagnosis

Ne

w C

an

cer

Ca

ses

pe

r 1

00

,00

0 P

eo

ple

Source: National Cancer Institute

Page 23: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian

Visit CancerProgress.Net for an interactive timeline of progress against a range of common cancers

CancerProgress.Net is a project of the American Society of Clinical Oncology, which represents nearly 30,000 physicians who treat people with cancer and

research new cures


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A Complete Bibliography of Publications in Isis 1970{1979ftp.math.utah.edu/pub/tex/bib/isis1970.pdf · 2019. 6. 20. · A Complete Bibliography of Publications in Isis, 1970{1979

Progress Against Melanoma. 1970–1979 Progress Against Melanoma 1970–1979 1978: Hereditary syndrome linked to increased melanoma risk

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Ovarian Cyst Causes | Ovarian Cyst Treatment |Ovarian Cyst Pain

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Progress Against Pancreatic Cancer. 1970–1979 Progress Against Pancreatic Cancer 1970–1979 1970s: Tobacco use found to cause pancreatic cancer

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