processes of evolution & genetics part 2. learning objectives 1.describe the importance of dna...
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Learning Objectives
1. Describe the importance of DNA replication2. Describe the mechanisms of inheritance at a cellular level
1. Explain the link between meiosis and Mendelian genetics2. Explain the evolutionary significance of meiosis
3. Illustrate an understanding of terms associated with evolutionary biology and genetics through defining and/or describing the terms
4. Distinguish between different forms of gene expression1. Illustrate an understanding of different forms of gene
expression through trait examples and visual diagrams
DNA Structure DNA = Deoxyribonucleic Acid
____________________________________
Discovered by:James Watson & Francis
Crick unlocked structure and Function of DNA
Revolutionized science
DNA Structure• DNA composed of chains of nucleotides. Each nucleotide,
in turn, is made of :• 1. • 2. • 3.
• Double helix is a _____________________
• DNA Bases: ___________________________
Chromosomes
• Two Basic Forms:• 1. • ___________
• 2. • ___________• ___________
X Chromosome
Y Chromosome
Chromosomes Somatic cells: __________________
Each pair - same genes _______________________________
Locus (pl., loci):
Allele:
Mutation
• Changes to the _______________• _____________________________________
• Is one of the _________________________
• Is the only source of __________________
• When does a mutation occur?• _________________________
Cell Division
• Source of Genetic Diversity Cell division and differences in division have evolutionary significance
• Only two types of cell in our bodies:• Somatic cells: such as hair, skin, liver, heart, muscle
tissue, etc
• Sex cells (gametes): egg, sperm
Mitosis: Somatic Cell Division
DNA replicates; Parent cell now has full set of chromosomes (23 pairs = 46 chromosomesReplicated
DNA lines up in middle of cell
During division DNA separates. One complete complement goes into one new cell, and the other into the second new cell
Each new cell has full set of DNA
Meiosis• Meiosis: development of ________________
• Only occurs in the testes and ovaries produce __________
• Sex cell division – daughter cells contain _______ ___________________________
• Meiosis involves __________________
Meiosis
Parent cell is diploid Begins
like mitosis; DNA replicated
DNA lines up at middle of cell
Cell divides & DNA separates, creating two diploid daughter cells
2nd cell division: each daughter cell splits into two more cells, and paired chromosomes are split
Each new cell has 23 chromosomes BUT NO PAIRS
Differences
• 1. • 2. • 3.
• Make sure that you can not only names these differences but can also describe them
Evolutionary Significance of Meiosis
• Meiosis – greatly increases genetic variation in a _____________
• ____________________________• (can) produce upwards of 10 billion unique
combinations multiplied by the # of possible combinations for any random mating
Evolutionary Significance of Meiosis• Linkage• Inheritance pattern in which _________________
______________________• Why? • ___________________________________
• Geneticists calculate linkage percentages
• This is an ____________ to Mendel’s principle of independent assortment
Genes & the Genome• Polygenic Inheritance • Cumulative effects of ________________
• __________________ contribute• Not ______________________• Expression on a _____________________ (continuous variation) – bell
shaped curve – _________________________
• Examples: Gene
Gene
Gene
Gene
Trait
Genes & the Genome• Pleiotropy• ___________________________________• Primary and secondary results
Gene
Trait
Trait
Trait
Trait
• Norm of Reaction• Table or graph illustrating the possible range of
phenotypic expression for a given genotype• Fruit Fly Example
Gene & the Genome