GROUP 141. Adatya Stephanie P.H. (L)2. Beatrix Flora E. Siregar3. Rananta S. Sembiring4. Alitha Rachma Oktavia5. Sufrianus Brian R.6. Karolus Refan

ABOUT THE DISEASE

This disease is a large swelling or lump on the front of the neck (the throat) and is due to the growth of thyroid abnormalities.Most disease is caused by a deficiency of iodine in food.

EPIDIMIOLOGY• Paramixovirus reservoir of the disease only in humans.

• Transmitted by salyvary infected secretions or urine during the six days before parotitis up to two weeks.

• Incubation of the disease between 12-25 days at the peak age of 10-19 years.

CLINICAL MANIFESTATIONS• Salivary adenitis: parotitis usually characterized by sudden pain, skin glan no worms or red (vs. bacterial parotitis) 38-39 C then fever, malaise, headache, anorexia.

• Epididymoorchitis: 20-35% of postpubertal males, usually 7-10 days after parotitis with the recrudescence of malaise, chills, fever; half followed by testicular atrophy, sterility if bilateral atrophy.

• CNS: Points and a half with goiter showed an increase of cells in the CSF, usually 3-10 days after onset of parotitis; rare - cerebellar ataxia was encephalitis, poliio syndromes such as paralysis, transverse myelitis,.

• pancreatitis: abdominal pain and tenderness rarely complicated by shock or pseudokista; to see an increase in amylase with parotitis only (but increases the lipase only with pancreatitis).

• Other: subacute thyroiditis, dacryoadenitis, neuritis, optic iritis, conjunctivitis, myocarditis, hepatitis, thrombocytopenic purpura, interstitial pneuomonia, migratory polyarthritis (esp.males age 20-30)

DIAGNOSIS• Laboratory findings: parotitis complicated relative lymphocytosis, leukocytosis characterized by orchitis, amylase increased, CSF: leukocyte 1000-2000 with initial PMNs (higher than aseptic meningitis with polio-coxsackie echoviruses, -, and).

• Cultures of blood, throat swabs, CSF, urine, in tissue culture, immunofluorescence postive in 2-3 d.

• Serology: increased four-fold titer by ELISA, CF (S initial antigen, V later)

TREATMENT• Treatment for chronic diseases that already this is usually with surgery. However, in the homeopathic treatment of goiter could be cured without surgery. With homeopathic medicine to decrease swelling of the thyroid gland and over time will be lost. Thyroid hormone production will be organized.

• Prednisone 60 mg qd tapered over 7-10 d may give symptomatic relief in orchitis.

• Prevention : Live attenuated vaccine (0.5 Ml 1M) after 1 year of age ; contraindicated if hypersensitivity reaction. febrile illness, malignancy, pregnancy.

THANK YOU FOR YOUR ATTENTION