Ancylostoma duodenaleAncylostoma duodenale

TaxonomyTaxonomy

Kingdom : AnimaliaKingdom : Animalia Phylum : NematodaPhylum : Nematoda Class : RhabditeaClass : Rhabditea Order : StrongylidaOrder : Strongylida Family : AncylostomatidaeFamily : Ancylostomatidae Genus : AncylostomaGenus : Ancylostoma Species : duodenale .Species : duodenale .

Old world hook wormOld world hook worm Causative agent ofCausative agent of ancylostomiasis ancylostomiasis Parasitic description by Parasitic description by DubiniDubini Mode of infection by LooseMode of infection by Loose Habitat : lumen of small intestineHabitat : lumen of small intestine

MorphologyMorphology : :

Adult wormAdult worm : cylindrical , greyish white , : cylindrical , greyish white , slightly curved .slightly curved .

ant. end : bent slightly in same direction ant. end : bent slightly in same direction of body curve .of body curve .

Buccal capsule : 6 teeth .Buccal capsule : 6 teeth . Post. end : bell shaped – copulatory bursa Post. end : bell shaped – copulatory bursa

– holding the female worm .– holding the female worm . Copulatory bursa : 13 rays in 3 lobes .Copulatory bursa : 13 rays in 3 lobes .

Adult worms

Buccal capsule

Copulatory bursa

Difference b/w male and femaleDifference b/w male and female

Caudal endCaudal endExpandedExpanded

Umbrella like Umbrella like shapeshape

TaperingTaperingNot expandedNot expanded

Genital Genital openingopening

Posterior partPosterior partIn b/w middle In b/w middle 1/3 and post. 1/3 and post.

partpart

Male Female

EggEgg : :

Size : 60 mc in L ,40 mc in B .Size : 60 mc in L ,40 mc in B . Shape : ovalShape : oval Non bile stained Non bile stained Thin shelled Thin shelled 8 blastomeres , clear space .8 blastomeres , clear space .

Filariform larvaFilariform larva

Non feeding formNon feeding form SlenderSlender 500 – 600 mc in L500 – 600 mc in L Pointed tailPointed tail Shorter oesophagusShorter oesophagus Infective form . Infective form .

PathogenesisPathogenesis

Source : human faecesSource : human faeces Host : manHost : man No intermediate hostNo intermediate host Route : PenetrationRoute : Penetration IngestionIngestion TransmammaryTransmammary Transplacental .Transplacental .

Life cycleLife cycle

Clinical manifestationsClinical manifestations

20 – 4020 – 40% % Asymptomatic

Skin manifestations : ground itch small itchy papules Site : around feet , b/w toes . Symptoms : intense itching edema erythema rash .

Respiratory manifestations :Respiratory manifestations :

Low grade feverLow grade fever Mild cough , pharyngitisMild cough , pharyngitis dyspnea , pneumonia .dyspnea , pneumonia . Intestinal manifestations :Intestinal manifestations : low grade fever , anaemia , git low grade fever , anaemia , git

disturbancesdisturbances Anaemia : hypochromic microcyticAnaemia : hypochromic microcytic types – mild , moderate , severe .types – mild , moderate , severe .

Lab diagnosisLab diagnosis

specimen : stoolspecimen : stool Methods : microscopy – direct wet mountMethods : microscopy – direct wet mount concentration – formalin concentration – formalin

etherether salt flotationsalt flotation kato katz methodkato katz method culture – harada mori method .culture – harada mori method . imaging methods : x – rays .imaging methods : x – rays .

TreatmantTreatmant

MebendazoleMebendazole

Pyrantel pamoatePyrantel pamoate

Thiabendazole .Thiabendazole .