poster_iac 2014_final

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An Integrated Tool to Test Mechanical Stability of Airborne Nanoparticles Yaobo Ding 1 , Michael Riediker 1,2 1 Institut de Santé au Travail (IST), Université de Lausanne, Switzerland 2 SAFENANO, IOM Singapore, Singapore, 048622, Singapore Contact: [email protected] ; [email protected] EXPOSURE INHALATION TRANSLOCATION Motivation Are nanoparticle agglomerates in the air stable ? How big are they ? Nanopowder handling Deposition in the lung Circulation in the body Method Results Aerosolization under different air flows Treatment under different energy input Changes in size and particle generation ACKNOWLEDGEMENT: This work is supported by the EU FP7 MARINA project (grant agreement no: 263215). The participation of this conference is funded by Fondation pour l’université de Lausanne” . The authors appreciate the support of the project and the foundation. Conclusions Stable aerosolization process Pressure drop seems to break up large agglomerates: reduction of particle size; increase of particle number Ranking of deagglomeration potential of engineered nanomaterials seems possible Test results can be useful for human exposure and risk assessment Figure 2 Particle number and size evolutions under different air flows Figure 3 Particle size distributions under different pressure conditions Figure 4 Particle sizes and generation rates under varied pressures SMPS OPC 10-42 nm primary particle sizes Figure 1 Schematic diagram of aerosolization and deagglomeration system

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Page 1: Poster_IAC 2014_Final

An Integrated Tool to Test Mechanical Stability of Airborne Nanoparticles

Yaobo Ding1, Michael Riediker1,2

1Institut de Santé au Travail (IST), Université de Lausanne, Switzerland 2 SAFENANO, IOM Singapore, Singapore, 048622, Singapore

Contact: [email protected]; [email protected]

EXPOSURE INHALATION TRANSLOCATION

Motivation

Are nanoparticle agglomerates in the air stable ? How big are they ?

Nanopowder handling Deposition in the lung Circulation in the body

Method

Results

Aerosolization under different air flows

Treatment under different energy input

Changes in size and particle generation

ACKNOWLEDGEMENT: This work is supported by the EU FP7 MARINA project (grant agreement no: 263215). The participation of this conference is funded by “Fondation pour l’université de Lausanne”. The authors appreciate the support of the project and the foundation.

Conclusions

Stable aerosolization process Pressure drop seems to break up large agglomerates: reduction of particle size; increase of particle number Ranking of deagglomeration potential of engineered nanomaterials seems possible Test results can be useful for human exposure and risk assessment

Figure 2 Particle number and size evolutions under different air flows

Figure 3 Particle size distributions under different pressure conditions

Figure 4 Particle sizes and generation rates under varied pressures

SMPS OPC

10-42 nm primary particle sizes

Figure 1 Schematic diagram of aerosolization and deagglomeration system