pit surabaya
DESCRIPTION
pneumonia anakTRANSCRIPT
Effectiveness of first 72 hours empirical antibiotic for pediatric pneumonia therapy in Dr. M. Djamil Hospital Padang period 2013-2014
BAGIAN / KSM ILMU KESEHATAN ANAK FK UNAND / RSUP DR.M.DJAMIL PADANG
Effectiveness of first 72 hours empirical antibiotic for pediatric pneumonia therapy in Dr. M. Djamil Hospital Padang period 2013-2014
Ranti Adriani, Finny Fitry Yani, Darfioes BasirDepartment of Pediatrics, Medical Faculty, Andalas University, Padang, Indonesia
2BackgroundRational treatment for pneumonia most likely pathogens in each community empiric antibiotic penicillin derivates first line therapyPneumonia , especially under 5 yo is the main cause of death in child, mostly cause by bacterial agent
However, the rapid global spread of antibiotic resistance may cause doubts on the effectiveness of empiric antibiotic therapy in these patients
WHO: 2014
ObjectiveTo assess the Effectiveness of first 72 hours empirical antibiotic for pediatric pneumonia therapy in Dr. M. Djamil Hospital Padang period januari 2013- desember 2014
METHODS
ResultTotal : 270 cases133 cases (subject)21 cases discharge before 72 hours 116 cases Medical record not complete
Characteristic subjectVariabelN %Gender Male7858.6 Female5541.4Age 1-2 months118.3 2-12 months8362.4 13-60 months3425.6 > 60 months53.8Nutritional status Malnourished32,3 Undernourished8563.9 Good 4533.8
Comorbid disease and complicated pneumonia
Empirically Antibiotic on first 72 hours pneumonia chidren
Respon of empirically antibiotic on 72 hours
The highest level was a combination of Amoxicillin-Chloramphenicol (97.4%). Severity of pneumoniaRespon of empirically antibiotic ImprovedfailedUncomplicated Pneumonia 73 (97,3%)2 (2,7%)Complicated Pneumonia23 ( 39,7%)35 (60,3%)
Respon empirical antibiotic on first 72 hours more effective on uncomplicated peneumonia than complicated pneumonia Length of StayRespon of empirically antibiotic on first 72 hoursimprovedfailed< 5 days48 (50 %)16 (43,2%)5-10 days40 (41,7 %)12 (32,4 %)P = 0,046>10 days8 (8,3 %)9 (24,3 %)
There was significant association with respon empirical antibiotic on first 72 hours with leght of stayOutcome
13Discussion
Children aged 259 months with severe pneumonia should be treated with parenteral penicillin group antibiotic and gentamicin or khloramfenicol as a first-line treatment Revised WHO classification and treatment of pneumonia in children at health facilities: evidence summariesGeneva: World Health Organization; 2014Penicillin group antibiotic was effective as empiric therapy for pneumonia children Discussion
Conclusion
There was significant association respon empirical antibiotic with leght of stayRespon empirical antibiotic on first 72 hours more effective on uncomplicated peneumonia than complicated of pneumonia Antibiotics empirically assessed was effective in treatment pneumoniaThank you