8/8/2019 Pen g Drug Study

1/1

Jean Therese P. Nicolas DRUG STUDY Mr. Rommel QuijanoGrp. 1 Student Headnurse

Drug Data ClassificationMechanism of

ActionIndication Contraindications Adverse Reaction

NursingResponsibilities

Generic NamePenicillin GBenzathine

Trade NamePenadur

Minimum Dose300,000 units IM

Maximum Dose2.4 million unitsIM weekly for 3weeks

Contents

Availability andcolor

- Injection:600,000, 1.2million, 2.4millionunits/dose

Route ofadministrationIntramuscular

PharmacologicClassificationPenicillin

TherapeuticClassAnti-infective,Antibiotic

PregnancyRisk FactorB

Interferes with bacterialcell wall synthesisduring activemultiplication, causingcell wall death andresultant bactericidalactivity againstsusceptible bacteria.

GeneralIndications- Severe infectionscaused by sensitiveorganisms(streptococci)- URTI caused bysensitivestreptococci- Treatment ofsyphilis, bejel,congenital syphilis,pinta, yaws- Prophylaxis ofrheumatic feverand chorea

Concentrations- Allergies topenicillins,cephalosporins, orother allergens

Precaution- Renal disorders- Pregnancy- Lactation

Drug interactionDrug to drug- Decreasedeffectiveness withtetracyclines- Inactivation ofparenteralaminoglycosides(amikacin, gentamicin,kanamycin, neomycin,tobramycin)

CNS: Lethargy,hallucinations,seizures

GI: Glossitis,stomatitis, gastritis,sore mouth, furrytongue, black hairytongue, nausea,vomiting, diarrhea,abdominal pain,bloody diarrhea,enterocolitis,pseudomembranouscolitis, nonspecifichepatitis

GU: Nephritis

Hematologic:Anemia,thrombocytopenia,leukopenia,neutropenia,prolonged bleedingitme

Hypersensitivity:Rash, fever, wheezing,anaphylaxis

Local: Pain, phlebitis,thrombosis at injectionsite, Jarisch-Herxheimer reactionwhen used to treatsyphilis

Other:Superinfections,sodium overloadleading to heart failure

Before- Observe 15 rights of drugadministration.- Reduce dosage withhepatic or renal failure.- Assess for hypersensitivityto drug.- Assess for anycontraindications to thedrug.- Educate about sideeffects of drug.

During- Drug is not for IV use. Donot inject or mix with otherIV solutions.

- Give IM injection in upperouter quadrant of thebuttock.- Avoid contact with theneedle.- Withdraw needle asquickly as possible to avoiddiscomfort.- Stay with patientthroughout whole durationof administration.

After- Monitor client for at least30 minutes.- Arrange for regular follow-up, including blood tests, toevaluate effects.- Instruct to report difficultybreathing, rashes, severepain at injection site, mouthsores, unusual bleeding orbruising.- Instruct to take medicationas directed for the fullcourse of therapy, even iffeeling better.

- Do proper documentation.