contact

Dr. Thomas Hundsberger

titel Dr. med.

first name Thomas

last name Hundsberger

street Rorschacherstr. 95

city 9007 St. Gallen

country Switzerland

phone number 0041 71 494 3095

fax 0041 71 494 2895

e-mail thomas.hundsberger@kssg.ch

2

publications

title

journalpaper/review

Leupold D, Felbecker A, Tettenborn B, Hundsberger T. Nerve Ultrasoundas a Decisive Tool in Nonsystemic Vasculitic Neuropathy: A Case Report.Case Rep Neurol 2016; 8:108-14.

Hundsberger T, Surbeck W, Hader C, Putora P M, Conen K, Roelcke U.[Meningioma: management of the most common brain tumour]. Praxis(Bern 1994) 2016; 105:445-51.

Hottinger A F, Perez L, Haegele-Link S, Hundsberger T. [Neurologicalcomplications of anticancer treatments]. Rev Med Suisse 2016;12:840-3.

Desax M C, Hundsberger T, Rothermundt C, Omlin A, Gillessen SommerS. Restless Legs Syndrome—An Emerging Potential Side Effect ofEnzalutamide: Report of 2 Cases. Clin Genitourin Cancer 2015; 13:e385-6.

Putora P M, Ess S, Panje C, Hundsberger T, van Leyen K, Plasswilm L,Früh M. Prognostic significance of histology after resection of brainmetastases and whole brain radiotherapy in non-small cell lung cancer(NSCLC). Clin Exp Metastasis 2015; 32:143-9.

Müller K, Henke G, Pietschmann S, van Gool S, De Vleeschouwer S, vonBueren A O, Compter I, Friedrich C, Matuschek C, Klautke G, Kortmann RD, Hundsberger T, Baumert B G. Re-irradiation or re-operation followedby dendritic cell vaccination? Comparison of two different salvagestrategies for relapsed high-grade gliomas by means of a new prognosticmodel. J Neurooncol 2015; 124:325-32.

3

publications

title

journalpaper/review

Korfel A, Thiel E, Martus P, Möhle R, Griesinger F, Rauch M, Röth A,Hertenstein B, Fischer T, Hundsberger T, Mergenthaler H G, Junghanß C,Birnbaum T, Fischer L, Jahnke K, Herrlinger U, Roth P, Bamberg M,Pietsch T, Weller M. Randomized phase III study of whole-brainradiotherapy for primary CNS lymphoma. Neurology 2015; 84:1242-8.

Hundsberger T, Hottinger A F, Roelcke U, Roth P, Migliorini D, Dietrich P Y,Conen K, Pesce G, Hermann E, Pica A, Gross M W, Brügge D, Plasswilm L,Weller M, Putora P M. Patterns of care in recurrent glioblastoma inSwitzerland: a multicentre national approach based on diagnostic nodes.J Neurooncol 2015; 126:175-83.

Leupold D, Krammer W, Dollmaier G, Hundsberger T. NeurologischeAspekte bei HIV und Syphilis: Wie manifestieren sich dieInfektionserkrankungen am Nervensystem. InFo Neurologie & Psychiatrie2015; 13:2-7.

Hundsberger T, Hottinger A F. Behandlungsoptionen von Hirnmetastasen:Neue Optionen durch orale und molekulare Therapeutika. info@onkologie2015; 5:5-7.

Hundsberger T, Roth P, Roelke U. Neurologische Komplikationen beionkologischen Patienten. Praxis 2014 2014; 103:1009-1016.

Hundsberger T, Brügge D, Hitz F. Leptomeningeal lymphomatosis fromlarge granular lymphocyte leukaemia. J Neurol 2014; 261:1221-1222.

Hundsberger T, Rösler K M, Findling O. Cessation and resuming ofalglucosidase alfa in Pompe disease: a retrospective analysis. J Neurol2014; 261:1684-1690.

4

publications

title

journalpaper/review

Hundsberger T, Tonder M, Hottinger A, Brügge D, Roelcke U, Putora P M,Stupp R, Weller M. Clinical management and outcome of histologicallyverified adult brainstem gliomas in Switzerland: a retrospective analysisof 21 patients. J Neurooncol 2014; 118:321-328.

Omlin A, Stienen M N, Brügge D, Fretz C, Gillessen Sommer S,Hundsberger T. Maligne spinale Kompression: Prävention, Erkennungund «State of the Art»-Behandlung. SMF 2014; 14:820-825.

Hundsberger T. Neuroborreliosis mimicking leptomeningealcarcinomatosis in a patient with breast cancer: A case report. Journal ofinvestigative medicine 2014; 2014:1-4.

Hundsberger T, Omlin A, Haegele-Link S, Vehoff J, Strasser F. AutonomicDysfunction in Cancer Cachexia Coincides With Large FiberPolyneuropathy. J Pain Symptom Manage 2014; 48:611-618.

Müller K, Henke G, Compter I, von Bueren A O, Friedrich C, Janssens G,Kramm C M, Hundsberger T, Paulsen F, Kortmann R D, Zwiener I,Baumert B G. External validation of a prognostic model estimating thesurvival of patients with recurrent high-grade gliomas after reirradiation.Pract Radiat Oncol 2014; 5:e143-50.

Schilg L, Haegele-Link S, Felbecker A, Weber J, Tettenborn B, Gers B,Hundsberger T. Intraneurale Ganglien: Ursache schmerzhafter N.-peronaeus-Paresen. PRAXIS 2014; 24:1433-1438.

Fischer S, Weber J, Senn-Schönenberger I, Cerny T, Hundsberger T.Neuroborreliosis Mimicking Leptomeningeal Carcinomatosis in a PatientWith Breast Cancer: A Case Report. J Investig Med High Impact Case Rep2014; 2:2324709614529417.

Hundsberger T, Roth P, Roelcke U. [Neurological complications in cancerpatients]. Praxis (Bern 1994) 2014; 103:1009-16.

5

publications

title

journalpaper/review

Schilg L, Haegele-Link S, Gers B, Felbecker A, Tettenborn B, HundsbergerT. Nerve sonography of intraneural ganglia as a cause of painful peronealpalsies: a case series. Praxis (Bern 1994) 2014; 103:1433-1438.

Schmid S, Gillessen Sommer S, Binet I, Brändle M, Engeler D, Greiner J,Hader C, Heinimann K, Kloos P, Krek W, Krull I, Stöckli S, Sulz M, vanLeyen K, Weber J, Rothermundt C, Hundsberger T. Management of vonHippel-Lindau Disease: An Interdisciplinary Review. Oncol Res Treat2014; 37:761-771.

Hottinger A F, Aissa A B, Espeli V, Squiban D, Dunkel N, Vargas M I,Hundsberger T, Mach N, Schaller K, Weber D C, Bodmer A, Dietrich P Y.Phase I study of sorafenib combined with radiation therapy andtemozolomide as first-line treatment of high-grade glioma. Br J Cancer2014; 110:2655-2661.

Putora P M, Panje C, Papachristofilou A, Pra A, Hundsberger T, PlasswilmL. Objective consensus from decision trees. Radiat Oncol 2014; 9:270.

Hundsberger T, Brügge D, Putora P M, Weder P, Weber J, Plasswilm L. Re-irradiation with and without bevacizumab as salvage therapy forrecurrent or progressive high-grade gliomas. J Neurooncol 2013;112:133-139.

Hochstrasser A, Hundsberger T, Siano M. Secondary spinal anaplasticependymoma ten years after treatment of Hodgkin’s disease. Schweiz.Krebs Bulletin 2013; 2:175-178.

6

publications

title

journalpaper/review

Korfel A, Weller M, Martus P, Roth P, Klasen H A, Roeth A, Rauch M,Hertenstein B, Fischer T, Hundsberger T, Leithäuser M, Birnbaum T,Kirchen H, Mergenthaler H G, Schubert J, Berdel W, Birkmann J, HummelM, Thiel E, Fischer L. Prognostic impact of meningeal dissemination inprimary CNS lymphoma (PCNSL): experience from the G-PCNSL-SG1trial. Ann Oncol 2012; 23:2374-2380.

Roelcke U, Bruehlmeier M, Hefti M, Hundsberger T, Nitzsche E U. F-18choline PET does not detect increased metabolism in F-18fluoroethyltyrosine-negative low-grade gliomas. Clin Nucl Med 2012; 37:e1-3.

Hundsberger T. Die Problematik der Enzymersatztherapie beim MorbusPompe (Glykogenose Typ II): Eine medizinische Einschätzung. SchweizMed Forum 2011; 11:427-429.

Hundsberger T, Cogliatti S B, Kleger G R, Fretz C, Gähler A, Anliker M D,Fournier J Y, von Moos R, Tettenborn B, Driessen C. Intravascularlymphoma mimicking cerebral stroke: report of two cases. Case RepNeurol 2011; 3:278-283.

Hundsberger T, Hohl U, Rösler K M. Die Glykogenose Typ II: MorbusPompe. Schweizer Archiv für Neurologie und Psychiatrie 2010;161:55-59.

Cadosch D, Collen T D, Land M, Hoederath P, Hildebrandt G, Fournier J Y,Hundsberger T. [Glioblastoma Multiforme - New Hope due to ModernTherapeutical Approaches.]. Praxis (Bern 1994) 2010; 99:295-308.

7

publications

title

journalpaper/review

Thiel E, Korfel A, Martus P, Kanz L, Griesinger F, Rauch M, Röth A,Hertenstein B, von Toll T, Hundsberger T, Mergenthaler H G, LeithäuserM, Birnbaum T, Fischer L, Jahnke K, Herrlinger U, Plasswilm L, Nägele T,Pietsch T, Bamberg M, Weller M. High-dose methotrexate with or withoutwhole brain radiotherapy for primary CNS lymphoma (G-PCNSL-SG-1): aphase 3, randomised, non-inferiority trial. Lancet Oncol 2010;11:1036-47.

Hundsberger T, Müller S, Sommacal A, Fretz C, Tettenborn B. Koinzidenzvon ischämischer Enzephalopathie und essentieller Thrombozythämie:zerebrale kortikale Venenthrombose ?. Schweizer Archiv für Neurologieund Psychiatrie 2010; 161:262-265.

Yaldizli O, Coco O, Hundsberger T, Tettenborn B. Pain in the sole of thefoot. Have you suspected its cause in the knee?. MMW Fortschritte derMedizin 2009; 151:5.

Roelcke U, Bruehlmeier M, Hefti M, Hundsberger T. Imaging blood-brainbarrier transporters in low-grade glioma patients with positron emissiontomography, tyrosine and choline. Schweiz Arch Neurol Psychiatr 2009;7:312-313.

Glas M, Hundsberger T, Stuplich M, Wiewrodt D, Kurzwelly D, Nguyen-Huu B, Rasch K, Herrlinger U. Nimustine (ACNU) plus teniposide (VM26)in recurrent glioblastoma. Oncology 2009; 76:184-9.

Tettenborn B, Yaldizli O, Hundsberger T. Pain in the sole of the foot. Haveyou suspected its cause in the knee?. MMW Fortschr Med. 2009; 151(19):5.

Kamm C P, Mattle H P, SWABIMS Study Group . SWiss Atorvastatin andinterferon Beta-1b trial In Multiple Sclerosis (SWABIMS)--rationale,design and methodology. Trials 2009; 10:115.

8

publications

title

journalpaper/review

Wiewrodt D, Nagel G, Dreimüller N, Hundsberger T, Perneczky A, Kaina B.MGMT in primary and recurrent human glioblastomas after radiation andchemotherapy and comparison with p53 status and clinical outcome.International journal of cancer. Journal international du cancer 2008;122:1391-9.

Koch D, Hundsberger T, Boor S, Kaina B. Local intracerebraladministration of O(6)-benzylguanine combined with systemicchemotherapy with temozolomide of a patient suffering from a recurrentglioblastoma. Journal of neuro-oncology 2007; 82:85-9.

Hau P, Koch D, Hundsberger T, Marg E, Bauer B, Rudolph R, Rauch M,Brenner A, Rieckmann P, Schuth J, Jauch T, Koch H, Bogdahn U. Safetyand feasibility of long-term temozolomide treatment in patients withhigh-grade glioma. Neurology 2007; 68:688-90.

Nitschke S, Hundsberger T, Haegele-Link S, Tettenborn B. Therapyrefractory Voltage-gated potassium channel antibody (VGKC-Ab) negativeneuromyotonia with generalized lymphadenopathy. Schweizer Archiv fürNeurologie und Psychiatrie 2007; 158:.

Herrlinger U, Rieger J, Koch D, Loeser S, Blaschke B, Kortmann R D,Steinbach J P, Hundsberger T, Wick W, Meyermann R, Tan T C, SommerC, Bamberg M, Reifenberger G, Weller M. Phase II trial of lomustine plustemozolomide chemotherapy in addition to radiotherapy in newlydiagnosed glioblastoma: UKT-03. Journal of clinical oncology : officialjournal of the American Society of Clinical Oncology 2006; 24:4412-7.

Hundsberger T, Wiewrodt D, Weber M. Tumorspezifische undsymptomorientierte Therapie maligner Gliome. Zeitschrift fürPalliativmedizin 2006; 7:11-18.

9

publications

title

journalpaper/review

Thömke F, Marx J J, Sauer O, Hundsberger T, Hägele S, Wiechelt J,Weilemann S L. Observations on comatose survivors of cardiopulmonaryresuscitation with generalized myoclonus. BMC neurology 2005; 5:14.

Thömke F, Marx J, Hundsberger T, Sauer O, Hägele-Link S, Weileman S.Der „myoklonische Status epilepticus“ nach kardiopulmonalerReanimation. Intensivmedizin 2004; 41:592-597.

Hundsberger T, Koch D, Klimpe S, Schlegel U. Temozolomid in derBehandlung maligner Gliome. Aktuelle Neurologie 2003; 30:184-187.

Thömke F, Weilemann S L, Hundsberger T, Marx J, Sauer O, Hägele-LinkS, Dieterich M. Verlaufsveränderungen des Burst-Suppression-EEG beihypoxischer Hirnschädigung nach kardiopulmonaler Reanimation.Klinische Neurophysiologie 2003; 34:86-93.

Vogt T, Nill M, Hundsberger T. Thalidomidinduzierte Polyneuropathie.Aktuelle Neurologie 2002; 29:149-152.

Hundsberger T, Thömke F, Hopf H C, Fitzek C. Symmetrical infarction ofthe cervical spinal cord due to spontaneous bilateral vertebral arterydissection. Stroke; a journal of cerebral circulation 1998; 29:1742.

Hundsberger T, Braun V, Weidmann M, Leukel P, Sauerborn M, von Eichel-Streiber C. Transcription analysis of the genes tcdA-E of the pathogenicitylocus of Clostridium difficile. European journal of biochemistry / FEBS1997; 244:735-42.

Braun V, Hundsberger T, Leukel P, Sauerborn M, von Eichel-Streiber C.Definition of the single integration site of the pathogenicity locus inClostridium difficile. Gene 1996; 181:29-38.

10

publications

title

bookchapter

Hundsberger T (2011). Brainstem tumors. In Brainstem disorders (pp.255-271). Berlin Heidelberg: Springer- Verlag.

Hundsberger T, & Wiewrodt D (2008). Hirnstammtumoren. InErkrankungen des Hirnstamms (pp. 243-258): Schattauer Verlag(Stuttgart, New York).

conferencepaper/poster

Hundsberger T (2015). Nerve sonography guided diagnosis of painfulperoneal palsies caused by in-traneural ganglia- a case series. InKlinische Neurophysiologie (pp. 194): Thieme.

Leupold D, Felbecker A, Tettenborn B, & Hundsberger T (2015).Neurosonographic findings in non-systemic vasculitic neuropathy. In (pp.1): Swiss Archives of Neurology and Psychiatry.

Leupold D, Schilg L, Felbecker A, Zieglgänsberger D, Tettenborn B, &Hundsberger T (2015). Chronic inflammatory demyelinatingpolyneuropathy- still a challenging diagnosis. In : Swiss Archives ofNeurology and Psychiatry.

Prochnicki A A, Zieglgänsberger D, Vehoff J, Müller S, Tettenborn B, &Hundsberger T (2015). Glioblastoma multiforme: Chameleon ofneurology A case report. In (pp. 1).

Hundsberger T (2014). Long-Term Interruption of Enzyme ReplacementTherapy with rhGAA in Pompe Disease Leads to Irreversible ClinicalDecline. In Volume 2, Sppl. 1/2015 (pp. 20): Journal of NeuromuscularDiseases,.

Felbecker A, Schilg L, Haegele-Link S, Gers B, Weber J, Tettenborn B, &Hundsberger T (2014). Detection of Intraneural Ganglia With NerveSonography as a Cause for Painful Peroneal Palsy: a Case Series andReview of the Literature. In Swiss Medical Forum (pp. 66):Schweizerischer Ärzteverlag.

11

publications

title

conferencepaper/poster

Leupold D, Schilg L, Hundsberger T, Tettenborn B, & Felbecker A (2013).Zungenmyokymien- Drei Fälle, verschiedene Ätiologien. In .

Kapauer M, Müller-Westermann J, Hollenstein M, Hundsberger T, &Tettenborn B (2013). EBV-assoziiertes, primäres B-Zell-Non-Hodgkin-Lymphom des ZNS (PCNSL) nach Lebertrans-plantation. In .

Schallegger K, Brügge D, Hitz F, Hundsberger T, Cathomas R, & PlasswilmL (2012). Case Report of a patient with LGL-Leukemia who Developed aLeptomeningeal Lymphomatosis. In (pp. 128): SASRO.

Leupold D, Felbecker A, Tettenborn B, & Hundsberger T (2012). Unilateralmyokymia of the tongue – two cases, different aetiologies. In SchweizerArchiv für Neurologie und Psychiatrie (pp. 23S).

Hundsberger T, Vehoff J, Haegele-Link S, Tettenborn B, & Strasser F(2011). Evaluation of the autonomic nervous system in patients withstage IV incurable, advanced solid tumours. In Clin Auton Res 2011 (pp.21: 428 (F8)).

Müller-Westermann J, Traichel B, Hundsberger T, Eychmüller S, &Tettenborn B (2011). Akute Wernicke-Enzephalopathie im Rahmen biliärbedingter rezidivierender Pankreatitiden-ein Fallbericht. In .

Brügge D, Putora P M, Hundsberger T, Weder P, van Leyen K, & PlasswilmL (2011). Re-Irradiation with Bevacizumab in Recurrent MalignantGliomas. In SASRO 2011 final program (pp. 101).

Walch J, Weber J, Tettenborn B, & Hundsberger T (2011). Radiation-Induced De Novo-Cavernoma after Treatment of Acute MyeloidLeukaemia. In .

12

publications

title

conferencepaper/poster

Frizsche D, Burkhardt C, Hundsberger T, & Tettenborn B (2007).Spontaneous, multifocal cervical liquor leakage causing an intracranialhypotension syndrome. In Schweiz Arch Neurol Psychiatr, 2007 (158(4))(pp. 10).

Vehoff J, Hundsberger T, Hitz F, & Tettenborn B (2007).Neurolymphomatosis as a single sign of tumor recurrence in a patientwith diffuse large B-cell lymphoma of the testis. In (pp. 34): SchweizArch Neurol Psychiatr;158(4):, P34.

Wunnicke K, Nitschke S, Hundsberger T, Tolnay M, & Tettenborn B(2007). Fatal outcome in a patient suffering from statin-inducedrhabdomyolysis, hypothyroidism and inclusion body myopathy. In (pp.36): Schweiz Arch Neurol Psychiatr 2007;158(4):.

Haegele-Link S, Burow A, Hundsberger T, & Tettenborn B (2007). L-Doparesponsive movement disorder in a young patient with mixed connectivetissue disease (sharp syndrome). In Movement Disorders 2007, Volume22/Supplement 16, Abstract number 705 (pp. 1).

workingreport

Hundsberger T, & Tabatabai G (2010). Niedergradige Gliome: BösartigeErkrankung mit vielen Facetten. Leading opinions: Neurologie &Psychiatrie: www.universimed.com.

presentation Leupold D, Kim O, Brugnolaro C, & Hundsberger T (2015). Tonguemyokymia as an unusual symptom of a meningioma of the craniospinaljunction. Presented at 7th Swiss neuro-oncology meeting, Rorschach.

Vehoff J, Haegele-Link S, Hundsberger T, & Tettenborn B (2011). Theevaluation of the autonomic nervous system using the Finometer Prodevice and sympathetic skin response (SSR): Results in 141 consecutivepatients. Presented at Jahrestagung der Schweizerischen Gesellschaft fürklinische Neurophysiologie (SGKN), Luzern.

13

publications

title

presentation Haegele-Link S, Hundsberger T, Vehoff J, & Tettenborn B (2009).Evaluation of the autonomic nervous system using the Finometer deviceand sympathetic skin responses (SSR).

Hundsberger T (2009). No treatment is best: Round table Low gradegliomas: Pros and cons. Presented at 183. Annual meeting of the SwissNeurology Society (SNG).

14

projects

title status

Funktionelle Evaluation des autonomen Nervensystems imZusammenhang mit der erstmaligen Einnahme von 0,5mgFingolimod (Gilenya®) bei Patienten mit schubförmigverlaufender Multipler Sklerose

completed

A Phase Ib/II, open-label, multicenter study of INC280 incombination with buparlisib in adult patients with recurrentglioblastoma

automat-icallyclosed

15

projects

title status

Avastin plus Radiotherapy in Elderly Patients with Glioblastoma(ARTE) A phase II, randomized, parallel-group, explorative,open labeled multi-center study of bevacizumab (Avastin®) inelderly subjects with newly diagnosed glioblastoma

completed

Prospektives durch Langzeitbeobachtung erstelltesSicherheitsregister von Patienten mit Multipler Sklerose, die anklinischen Versuchen mit Cladribine teilgenommen haben

completed

16

projects

title status

Randomisierte, doppelblinde, placebokontrollierte klinischePrüfung der Phase III mit Parallelgruppen zur Beurteilung derWirksmkeit und Sicherheit von Desmoteplase bei Patienten mitakuten ischämischem Schlaganfall DIAS III

aborted

17

projects

title status

Cilengitide for subjects with newly diagnosed glioblastomamultiforme and methylated MGMT gene promotor - amulticenter, open-label, controlled phase III study, testingcilengitide in combination with standard treatment(temozolomide with concomitant radiation therapy, followed bytemozolomide maintenance therapy) versus standard treatment(CENTRIC)

completed

18

projects

title status

Doppelblinde, placebokontrollierte, multizentrische fortgesetzteParallelgruppenstudie der Phase IIIb zur Beurteilung derSicherheit und Verträglichkeit von oralem Cladribin beiTeilnehmern mit schubförmig verlaufender Multipler Sklerose,die bereits Studie 25643 (CLARITY) abgeschlossen haben

completed