pathophysiology of dm (type 2)
DESCRIPTION
DM (Type 2) pathophysiology and complications.TRANSCRIPT
PATHOPHYSIOLOGY
PREDISPOSING FACTORS Age Hereditary
PRECIPITATING FACTORS Obesity Dietary intake Stress Lifestyle
INSULIN RESISTANCE
DERANGED INSULIN RELEASE
↑ed hepatic glucose uptake
↓ed glucose uptake
Hyperglycemia
DM (TYPE II)
S/S: Glycosuria Polyuria Nocturia Polydipsia
Diabetic ketoacidosisS/S: Polyuria Polydipsia N and V Hypotension Tachycardia Fruity smell Kussmaul breathing
NephropathyRetinopathy
Blindness
Atherosclerosis
Sugar deposits like fat in the wall of the blood vessel
Myocardial infarction
Neuropathy
Skin break
Impaired pain sensation
Impaired host defenses
Infection
↑ed serum glucose level
Prone to injuryBlockage of tiny blood
vessels
↓ed blood supply in the eye
Blurry vision
Destruction of retinal blood vessels
Death
Severe infection
↓ed size of the lumen
↓ed renal perfusion
Impaired renal function
Renal failure
Coma