one lung ventilation · 2020. 3. 22. · one lung ventilation zogheib elie md anesthesia and...
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ONE LUNG VENTILATION
ZOGHEIB Elie MDAnesthesia and Intensive Care Department
Cardio Thoracic and Vascular Intensive Care Unit
INSERM U1088
CHU Amiens – Picardie, France
Agenda
• Indications
• Hypoxic pulmonary vasoconstriction
• VILI and Protective ventilation
• Hypoxemia and OLV
• Devices for OLV
• OLV and anesthesia
• OLV and simulation
Indications
• Surgical procedures
Thoracic surgeries
• Lung resection procedures:
• Bullectomy
• Pneumonectomy
• Lobectomy
• Wedge resection
• Video-assisted thoracoscopic surgery (VATS)
• Decortication
• Diaphragmatic hernia repair (thoracic approach)
• Single-lung transplant post-operative complications
M.K. Ferguson, W.T. Vigneswaran / European Journal of Cardio-thoracic Surgery 33 (2008) 496—500
M.K. Ferguson, W.T. Vigneswaran / European Journal of Cardio-thoracic Surgery 33 (2008) 496—500
Cardiovascular surgery
• Minimally invasive cardiac surgeries:
• Valve repairs/replacements
• Aortic arch surgeries:
• Dissecting aneurysm of aortic arch
• Repair of pericardial window
• Pericardiectomy
Esophageal surgery
• Minimally invasive thoraco-laparoscopic
oesophagectomy.
Indications
• Surgical procedures
• Non-thoracic surgeries
Non-thoracic surgeries
• Anterior fixation of the thoracic spine
Indications
• Surgical procedures
• Non-thoracic surgeries
• Non-surgical indications
Non-surgical indications
• Pulmonary lavage
• Split/differential lung ventilation
• Unilateral lung haemorrhages
• Ventilation in bronchopleural fistulae
• Prevention of spillage from infective to the non-
infective lung
Effect of gravity: V/P
55 45
65
35
The lower lung is the most perfused
Relationship between ventilation and perfusion
Effect of lateral decubitus position
during the spontaneous ventilation
Pleural pressure is less negative on the dependent lung.
The lower lung is on a better part of the lung compliance curve.
of the compliance for both lungs.
The higher lung is on a better part of the lung compliance curve.
Effect of lateral decubitus position
during the mechanical ventilation
OLV
OLV
=
1 lung perfused and not ventilated
=
Shunt flow A-V +++
PaO2 (mmHg)
SaO2 (%)
100
SaO2 = 85 % PaO2 = 65 mmHg
20
40
60
80
100 200 300 400
QS .CvO2 (QS - QS ) .CcO2
QT .CaO2
QS/QT = 50 %
OLV and shunt
PaO2 and OLV
• Preoperative perfusion of the lung (scintigraphy)
PaO2 and OLV
• Preoperative perfusion of the lung
• Gravity
• Hypoxemic vasoconstriction of the non ventilated
lung
• Vascular resistance of the ventilated lung
Hypoxic pulmonary
vasoconstriction (HPV)
HPV reduces blood flow to poorly ventilated lung areas in an attempt to
improve ventilation/perfusion (V/Q) matching
Anesthesiology 2015; 122: 932-46
Figure 1. Homeostatic Oxygen-Sensing System
Specialized tissues that sense the local oxygen level are shown. The carotid body at the carotid-
artery bifurcation increases action-potential frequency in the carotid-sinus nerve in response
to hypoxia, thus stimulating respiration. The small resistance pulmonary and fetoplacental
arteries demonstrate hypoxic vasoconstriction, optimizing oxygen transfer in the lung and
placenta. The ductus arteriosus, by contrast, contracts when oxygen levels rise, redirecting
blood through the newly expanded lungs of the newborn. The neuroepithelial bodies in the
lungs and adrenomedullary cells in the fetus also sense oxygen.
Weir et al. Page 16
N Engl J Med. Author manuscript; available in PMC 2010 January 7.
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Acute Oxygen-Sensing Mechanisms
N Engl J Med. 2005 November 10; 353(19): 2042–2055
Figure 1. Homeostatic Oxygen-Sensing System
Specialized tissues that sense the local oxygen level are shown. The carotid body at the carotid-
artery bifurcation increases action-potential frequency in the carotid-sinus nerve in response
to hypoxia, thus stimulating respiration. The small resistance pulmonary and fetoplacental
arteries demonstrate hypoxic vasoconstriction, optimizing oxygen transfer in the lung and
placenta. The ductus arteriosus, by contrast, contracts when oxygen levels rise, redirecting
blood through the newly expanded lungs of the newborn. The neuroepithelial bodies in the
lungs and adrenomedullary cells in the fetus also sense oxygen.
Weir et al. Page 16
N Engl J Med. Author manuscript; available in PMC 2010 January 7.
NIH
-PA
Auth
or M
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tN
IH-P
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Acute Oxygen-Sensing Mechanisms:HYPOXIC PULMONARY VASOCONSTRICTION
N Engl J Med. 2005 November 10; 353(19): 2042–2055
Figure 1. Homeostatic Oxygen-Sensing System
Specialized tissues that sense the local oxygen level are shown. The carotid body at the carotid-
artery bifurcation increases action-potential frequency in the carotid-sinus nerve in response
to hypoxia, thus stimulating respiration. The small resistance pulmonary and fetoplacental
arteries demonstrate hypoxic vasoconstriction, optimizing oxygen transfer in the lung and
placenta. The ductus arteriosus, by contrast, contracts when oxygen levels rise, redirecting
blood through the newly expanded lungs of the newborn. The neuroepithelial bodies in the
lungs and adrenomedullary cells in the fetus also sense oxygen.
Weir et al. Page 16
N Engl J Med. Author manuscript; available in PMC 2010 January 7.
NIH
-PA
Auth
or M
anu
scrip
tN
IH-P
A A
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or M
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IH-P
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Figure 4. Redox Mechanism for Oxygen Sensing in Specialized Tissues
Reactive oxygen species (ROS) from the mitochondria, NADPH oxidase, NADH oxidase, or
redox couples may control potassium-channel gating and membrane potential (E m) and thus
calcium entry. The same redox signaling may control calcium release from the sarcoplasmic
reticulum. The calcium stores in the sarcoplasmic reticulum, in turn, are repleted by calcium
entry through the store-operated channels. Rho kinase augments the response of actin–myosin
at any level of cytosolic calcium (Ca2+i). SOD denotes superoxide dismutase, H2O2 hydrogen
peroxide, GSH glutathione, and GSSG oxidized glutathione.
Weir et al. Page 19
N Engl J Med. Author manuscript; available in PMC 2010 January 7.
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N Engl J Med. 2005 November 10; 353(19): 2042–2055
Acute Oxygen-Sensing Mechanisms:HYPOXIC PULMONARY VASOCONSTRICTION
Time course of HPV during OLV
-Ventilation has returned completely to its initial two-lung value
-Perfusion remains significantly less (*P < 0.01) than its initial two-lung value due to residual HPV.
Br J Anesth 2008; 100: 549-59
Shunt fraction and cardiac output
Copyright © Lippincott Williams & Wilkins. Unauthorized reproduction of this article is prohibited.
values, CaO2 is reduced because high VO2/Qt ratios
increase the value of the second term in Equation 5. With
increasing cardiac output, this ratio decreases, causing
CaO2 to increase steeply until the VO2/Qt ratio assumes
such small values that the second term in Equation 5
becomes negligible. T heoretically, CaO2 approaches
CcO2 asymptotically at high cardiac outputs. Plot B illus-
trates how the relationship shifts downwards if the shunt
fraction doubles to 0.4. Plot C shows how plot B moves
upwards and to the left if oxygen consumption is halved
but the other criteria used to construct plot B are
unchanged. Plot D demonstrates that, if Hb is reduced
from 15 to 10g/dl, curve A is shifted downwards.
T hese complex relationships are depicted by the three-
dimensional graphs (Fig. 4) that show how, at two differ-
ent hemoglobin concentrations, cardiac output and shunt
fraction both determine CaO2. T he curvilinear surfaces
result from the shape of the oxygen dissociation curve.
In view of the steep arterial –mitochondrial oxygen gra-
dient, an adequate arterial oxygen tension (PaO2) is
needed to maintain intra-mitochondrial oxygen tensions
above the minimum required for aerobic metabolism.
Figure 5 depicts the relationship between cardiac output
and PaO2. ComparingFigs4and 5, it isinteresting tonote
that decreasing Hb (plots A and D) does not (theoreti-
cally) have as great an influence on PaO2 as on CaO2.
T he graphs in Figs 2–5 serve the purpose of illustrating
physiologic theory. In reality, there are combinations of
shunt fraction and cardiac output that would result in
such low values for oxygen content, tension and delivery
that are incompatible with life. Furthermore, the model
assumes that changes in cardiac output do not lead to
changes in shunt fraction. T his assumption is not always
correct and the practical implications thereof will be
addressed.
Unfortunately, there have been few attempts to use a
systematic approach to oxygenation during OL A, and this
30 Thoracic anaesthesia
Figure 5 The influence of cardiac output on PaO2 as predictedby Equation 5
The values used to plot these relationships are at FiO2 of 0.5 and PaCO2
40 mmHg. The curves have similar conditions to those specified in Fig. 4.Construction of this relationship used a lookup table in Excel relatingCaO2 to saturation for a particular Hb and then using an oxygendissociation curve to relate saturation to PaO2.
Figure 4 Two views of a three-dimensional plot of the influence of changing both cardiac output and shunt fraction on arterial oxygencontent (CaO2) at hemoglobin concentrations of 8 and 12 g/ 100 ml blood as predicted by Equation 5
The values used to plot these relationships are at FiO2 of 0.5 and PaCO2 40 mmHg.
HPV affected by variations in cardiac output.
Curr Opin Anaesthesiol 2008 : 21:28–36
ALI and OLV
Anesth Analg 2003;97:1558 -65
Lung protective ventilation
N Engl J Med 2000;342:1301-8.
Lung protective ventilation
• In ARDS patients:
• Understanding of the pathophysiology of the ARDS
• Recognition of VILI
• Ventilatory management modification
• Since 2000: ARDSnet:
• 6ml/kg of PBW
• Plateau pressure: < 30cmH2O
• High respiratory rate
N Engl J Med 2000;342:1301-8.
Lung protective ventilation
• In ARDS patients:
• 6ml/kg of PBW
• Plateau pressure: < 30cmH2O decrease mortality from 39.8 to 31%
Lung protective ventilation - VILI
• In ARDS patients:
• Understanding of the pathophysiology of the ARDS
• Recognition of VILI
• Ventilatory management modification
• Since 2000: ARDSnet:
• 6ml/kg of PBW
• Plateau pressure: < 30cmH2O decrease mortality from 39.8 to
31%
Low-Tidal-Volume
VILI
• Low Vt
• High PEEP
• Less VILI
• Better outcome
• During surgery
• In OLV: unknown ??
The impact of tidal volume on pulmonary complications
following minimally invasive esophagectomy: a
randomized and controlled study
• 101 patients: left-lung ventilation during thoracoscopic
esophagectomy.
• Randomisation:
• low VT (5 mL/kg + 5 cm H2O PEEP): preserved
ventilation (PV) group (n = 53)
• conventional VT (8 mL/kg) controlled ventilation (CV)
group (n = 48)
J Thorac Cardiovasc Surg 2013 Nov;146(5):1267-73
The impact of tidal volume on pulmonary complications
following minimally invasive esophagectomy: a
randomized and controlled study
After 18h PV CV p
IL-1b (pg/mL) 25.42 ± 31.01 94.96 ± 118.24 <0,05
IL-6 30.86 ± 75.78 92.99 ± 72.90 <0,05
IL-8 258.75 ± 188.24 403.95 ± 151.44 <0,05
J Thorac Cardiovasc Surg 2013 Nov;146(5):1267-73
The impact of tidal volume on pulmonary complications
following minimally invasive esophagectomy: a
randomized and controlled study
J Thorac Cardiovasc Surg 2013 Nov;146(5):1267-73
The impact of tidal volume on pulmonary complications
following minimally invasive esophagectomy: a
randomized and controlled study
After 18h PV CV p
IL-1b (pg/mL) 25.42 ± 31.01 94.96 ± 118.24 <0,05
IL-6 30.86 ± 75.78 92.99 ± 72.90 <0,05
IL-8 258.75 ± 188.24 403.95 ± 151.44 <0,05
J Thorac Cardiovasc Surg 2013 Nov;146(5):1267-73
-Pulmonary complications were observed in 18 cases:
on the ventilation side (right, 6 cases; and left, 12 cases).
The impact of tidal volume on pulmonary complications
following minimally invasive esophagectomy: a
randomized and controlled study
After 18h PV CV p
IL-1b (pg/mL) 25.42 ± 31.01 94.96 ± 118.24 <0,05
IL-6 30.86 ± 75.78 92.99 ± 72.90 <0,05
IL-8 258.75 ± 188.24 403.95 ± 151.44 <0,05
J Thorac Cardiovasc Surg 2013 Nov;146(5):1267-73
-Pulmonary complications were observed in 18 cases:
on the ventilation side (right, 6 cases; and left, 12 cases).
-The occurrence of pulmonary complications in the PV group was lower than
that in the CV group (9.43% vs 27.08%; P = .021).
Intraoperative Tidal Volume as a Risk Factor for
Respiratory Failure after Pneumonectomy
• 170 eligible study patients.
• Underwent pneumonectomy.
• 30 (18%) postoperative respiratory failure.
Anesthesiology, V 105, No 1, Jul 2006: 14-18
Intraoperative Tidal Volume as a Risk Factor for
Respiratory Failure after Pneumonectomy
Anesthesiology, V 105, No 1, Jul 2006: 14-18
8,3 Vs 6,7 ml/kg OR 1,56 per ml/kg
N Engl J Med 2015;372:747-55.
N Engl J Med 2015;372:747-55.
N Engl J Med 2015;372:747-55.
Impact of Tidal Volume on Complications
after Thoracic Surgery
• Retrospective data collection.
• VT was calculated on the basis of actual body weight(ABW) and predicted body weight (PBW).
• The nonventilated lung can be considered to be at least partially collapsed
• Driving pressure (∆P) and static compliance (Cs) weredefined and calculated as follows:
• ∆P = Pplat − PEEP;
• Cs = VT /(Pplat − PEEP).
ANESTHESIOLOGY 2016; 124:00-00
Impact of Tidal Volume on Complications
after Thoracic Surgery
ANESTHESIOLOGY 2016; 124:00-00
Impact of Tidal Volume on Complications
after Thoracic Surgery
ANESTHESIOLOGY 2016; 124:00-00
Impact of Tidal Volume on Complications
after Thoracic Surgery
ANESTHESIOLOGY 2016; 124:00-00
Impact of Tidal Volume on Complications
after Thoracic Surgery
ANESTHESIOLOGY 2016; 124:00-00
Impact of Tidal Volume on Complications
after Thoracic SurgeryPrimary outcome
ANESTHESIOLOGY 2016; 124:00-00
Impact of Tidal Volume on Complications after
Thoracic SurgeryPrimary outcome
ANESTHESIOLOGY 2016; 124:00-00
ΔP = VT
/CRS
(CRS
): respiratory-system compliance(VT
): tidal volumes
Impact of Tidal Volume on Complications
after Thoracic SurgerySecondary outcome
ANESTHESIOLOGY 2016; 124:00-00
Impact of Tidal Volume on Complications after
Thoracic SurgerySecondary outcome
ANESTHESIOLOGY 2016; 124:00-00
Independant risk factor of ALI
• Peak inspiratory pressure > 40 cm H2O
• Plateau pressure > 29 cm H2O
• Excessive perioperative fluid infusion
• Pneumonectomy
• Preoperative alcohol abuse
OLV and hypoxemia
OLV and hypoxemia
Hypoxémia = Sa02 < 95%
OLV and hypoxemia
Hypoxémia = Sa02 < 95%
Failure of lung isolation: mechanism for intraoperative hypoxemia.
OLV and hypoxemia
Hypoxémia = Sa02 < 95%
Failure of lung isolation: mechanism for intraoperative hypoxemia.
-DLT position
-Routine fibreoptic bronchoscopy
-Confirm initial placement of the lung isolation device.
Kinking of a Left-Sided Double-Lumen Tube Within the
TracheaDae-Kee Choi, MD, Jai-Hyun Hwang, MD, Myung-Hee Song, MD, and Kyung-Don Hahm,
MD
Journal of Cardiothoracic and Vascular Anesthesia, Vol 25, No 6 (December), 2011: pp 1119-1120
Kinking of a Left-Sided Double-Lumen Tube Within the
TracheaDae-Kee Choi, MD, Jai-Hyun Hwang, MD, Myung-Hee Song, MD, and Kyung-Don Hahm,
MD
Journal of Cardiothoracic and Vascular Anesthesia, Vol 25, No 6 (December), 2011: pp 1119-1120
Hypoxemia and OLV
FiO20.3 0.4 0.5 0.6 0.7 0.8 0.9 1
1 510
1520
25
30
40
50
0.20
50
100
150
200
250
300
350
400
450PaO2
(mm Hg)
Nunn’s Iso-Shunt Curves
FiO2 is efficient if the shunt < 25 / 30%
OLV and per operative hypoxemia
• Inflate the superior
lung intermittently.
• Apply a continuous positive
airway pressure on
the tracheal tube with
PEEP between 3 and 5.
OLV and per operative hypoxemia
• Inflate the superior
lung intermittently.
• Apply a continuous positive
airway pressure on
the tracheal tube with
PEEP between 3 and 5.
Selective lobar blockade
• Selective one-lobe ventilation
• Maintenance or improvement of arterial
oxygenation in patients who might not tolerate
complete lung collapse.
CPAP and blocker
-To decrease atelectasis
-Recruitment maneuver: carefull
-Risk if emphysema in the lower lung
OLV and per operative hypoxemia
Hypoxemia during one-lung
ventilation
Journal of Cardiothoracic and Vascular Anesthesia, Vol 23, No 6 (December), 2009: pp 850-852
Conf actualisation SFAR 2009
OLV and hypoxemia
• Pulmonary artery clamp
• Two lung ventilation
• Nitric oxide ?
• Almitrine
OLV – hypoxemia - NO
100
200
300
400
500
600
0 10' 20'
TEMPS (min)
VUP (et NO)
DDVBP
DLVBP
PaO2 (mmHg)
30'
NOTémoin
Anesth Analg 1997;85:1130-5
Anesth Analg 2002;94:830 -4
-Almitrine 8µ/kg/min.
Anesth Analg 2004;98:590 -4
18 patients
Almitrine
12 µ/kg/min (10 min)
then 4 µ/kg/min
Hyperinflation
6,14 cm² 9,74 cm²Under mechanical ventilation After ventilator deconnection
How to set up ventilator
• Vt 5-6 ml/kg IBW
• Low plateau pressure
• RR (12-13/min)
• PEP = 5 cm H20 (3-10 cm H2O)
• I/E à 1/3
• I:E ratio to 1:1-2:1 for restrictive lung disease.
• I:E ratio to 1:4-1:6 for obstructive lung disease to avoid intrinsic PEEP.
Positive end expiratory pressure during one-lung
ventilation: Selecting ideal patients and ventilator
settings with the aim of improving arterial oxygenation
Figure 1: PaO2 on OLV during PEEP0, PEEP5, and PEEP10. Average PaO2 values were as follows: PEEP 0 = 149 ± 80 mmHg, PEEP 5 = 144 ± 76 mmHg, PEEP 10 =
146 ± 78 mmHg. (a) PEEP responders (n = 12): increase in PaO2 of at least 20% from baseline. (b) Non-responders (n = 29): no increase in PaO2 of 20%, or a decrease
in PaO2.
Ann Card Anaesth. 2011 Sep-Dec;14(3):183-7. doi: 10.4103/0971-9784.83991.
How to set up ventilator
• Vt 5-6 ml/kg IBW
• Low plateau pressure
• RR (12-13/min)
• PEP = 5 cm H20 (3-10 cm H2O)
• I/E à 1/3
• I:E ratio to 1:1-2:1 for restrictive lung disease.
• I:E ratio to 1:4-1:6 for obstructive lung disease to avoid intrinsic PEEP.
Anatomy
Man 19 ± 6 mm
Woman 15 ± 5 mmMan 49 ± 8 mm
Woman 44 ± 7 mm
Double lumen tube
Fibre-optic view of tracheal and
bronchial carina
DLT size
• Small DLT: • So far threw the bronchius
• Over-inflation of the cuff with risks of bronchial or tracheal ischemia
• Increase of the hyperinflation
• Big size DLT• Proximal intubation: Herniated bronchial cuff in
the trachea
• Bronchial trauma
• Right bronchial trauma
DLT misplacement
Anesthesiology 2009; 110:1402–11
Right side DLT
Current Opinion in Anaesthesiology 2009, 22:4 - 10
Left side DLT
Current Opinion in Anaesthesiology 2009, 22:4 - 10
Double-lumen tracheal tubes
Carinal hook Without carinal hook
Right White Robertshaw
Left Carlens Bryce-Smith/
Size: 26 to 41F
DLT size
< 1,60 m 35 F
1,60 - 1,70 m 37 F
> 1,70 m 39 F
< 1,60 m 37 F
1,60 - 1,70 m 39 F
> 1,70 m 41 F
Women Man
Double lumen tube for tracheostomized patient
Tracheopart (Rüsch)
Arndt blocker
Arndt blocker with Cook's multi-port adapter
Current Opinion in Anaesthesiology 2009, 22:4 - 10
Arndt blocker
Current Opinion in Anaesthesiology 2009, 22:4 - 10
Arndt blocker
Cohen blocker
Univent blocker
EZ blocker
External Tracheal Manipulation Maneuver (ETMM) to Facilitate
Endobronchial Blocker Placement
Journal of Cardiothoracic and Vascular Anesthesia, Vol ], No ] (Month), 2016
• Easy recognition of anatomy if the tip of a single
tube is above carina.
• Best device for patients with difficult airways
• No cuff damage during intubation
• No need to replace a tube if mechanical ventilation
is needed / already intubated patient.
• Children OLV.
OLV and BlockerAdvantages
• Small channel for suctioning
• Conversion from 1 to 2 then to 1 lung ventilation
• High maintenance device (dislodgement or loss seal
during surgey.
OLV and BlockerDisadvantages
A Comparison of the Efficacy and Adverse Effects of Double-Lumen
Endobronchial Tubes and Bronchial Blockers in Thoracic Surgery:
A Systematic Review and Meta-analysis of Randomized Controlled Trials
• Malposition
JournalofCardiothoracicandVascularAnesthesia, Vol29,No4(August),2015:pp955–966
A Comparison of the Efficacy and Adverse Effects of Double-Lumen
Endobronchial Tubes and Bronchial Blockers in Thoracic Surgery:
A Systematic Review and Meta-analysis of Randomized Controlled Trials
• Time to positionning
JournalofCardiothoracicandVascularAnesthesia, Vol29,No4(August),2015:pp955–966
A Comparison of the Efficacy and Adverse Effects of Double-Lumen
Endobronchial Tubes and Bronchial Blockers in Thoracic Surgery:
A Systematic Review and Meta-analysis of Randomized Controlled Trials
• Lung collapse
JournalofCardiothoracicandVascularAnesthesia, Vol29,No4(August),2015:pp955–966
Video-Capable Double-Lumen Endotracheal
Tubes in Thoracic Surgery
Journal of Cardiothoracic and Vascular Anesthesia, Volume 28, Issue 4, 2014, 870–872
Video-Capable Double-Lumen Endotracheal
Tubes in Thoracic Surgery
Journal of Cardiothoracic and Vascular Anesthesia, Volume 28, Issue 4, 2014, 870–872
Video-Capable Double-Lumen Endotracheal
Tubes in Thoracic Surgery
Journal of Cardiothoracic and Vascular Anesthesia, Volume 28, Issue 4, 2014, 870–872
Video-Capable Double-Lumen Endotracheal
Tubes in Thoracic Surgery
Journal of Cardiothoracic and Vascular Anesthesia, Volume 28, Issue 4, 2014, 870–872
DOUBLE-LUMEN TUBE VIVASIGHT-DL
(DLT-ETVIEW)
Journal of Cardiothoracic and Vascular Anesthesia, Vol 29, No 6 (December), 2015: pp 1544–1549
DOUBLE-LUMEN TUBE VIVASIGHT-DL
(DLT-ETVIEW)
• Continuous visualization of the carina is a major improvement for patient.
• Intraoperative displacement is diagnosed immediatelyand corrected before any clinical effects.
• When FOB is not a routine procedure
• During robotic lobectomies because the anesthesiologist is placed far from the patient’s headand a continuous visualization of correct tube
Journal of Cardiothoracic and Vascular Anesthesia, Vol 29, No 6 (December), 2015: pp 1544–1549
Characteristics of Double-Lumen Tubes
Determine Bronchial Airway Pressure
Characteristics of Double-Lumen Tubes Determine Bronchial Airway Pressure. Journal of Cardiothoracic and Vascular Anesthesia, http://dx.doi.org/10.1053/j.jvca.2016.03.126
Evaluation of pH in removed double-lumen
tracheal tubes after general anesthesia:
A prospective observational study5
Journal of Cardiothoracic and Vascular Anesthesia, http://dx.doi.org/10.1053/j.jvca.2016.03.142
Evaluation of pH in removed double-lumen
tracheal tubes after general anesthesia:
A prospective observational study
5
-Low incidence of regurgitation of gastric fluid for well-prepared elective lung
surgery patient.
-No evidence of regurgitation in the stand care of patients using DLT for lung
isolation in the lateral position.
Journal of Cardiothoracic and Vascular Anesthesia, http://dx.doi.org/10.1053/j.jvca.2016.03.142
Relationship between V/P ventilation with surgical pneumothorax
Spontaneous inspiration Exhalation phase
Paradoxical ventilation and mediastinal shift
Ann Transl Med 2015;3(8):106
Spontaneous inspiration
Exhalation phase
Paradoxical ventilation and mediastinal shift
Ann Transl Med 2015;3(8):106
-Excluded and not ventilated lung continues to be perfused.
-Right-left intrapulmonary shunt, condition that involves an
increased risk of intraoperative hypoxemia.
-HPV: pulmonary arteries of hypoxic alveoli constrict and
divert the blood flow to the arteries of well oxygenated alveoli.
-Simple oxygen administration through a Venturi mask can
easily correct a decrease in arterial oxygenation in an awake
patient undergoing surgical pneumothorax.
-Dependent lung has been shown to be able to compensate for
decrease in oxygenation
Relationship between V/P ventilation with surgical pneumothorax
Spontaneous inspiration
Exhalation phase
Paradoxical ventilation and mediastinal shift
Ann Transl Med 2015;3(8):106
-Air enters the pleural space through the surgical access on
the chest wall, and transmitted atmospheric pressure
determines the non-dependent lung collapse allowing an
adequate surgical access.
-Increase in the ratio between airways size and lung
volume, increases the expiratory flow and the speed of
pulmonary emptying.
Relationship between V/P ventilation with surgical pneumothorax
Tracheal injury
Ann Fr Anesth Reanim 13:127-9, 1994
Traumatic rupture of the right bronchus
Effect of inhalation anesthesia vs Propofol
• General anesthesia during mechanical ventilation
can mediate several immune effects which may
affect postoperative outcomes.
Propofol Volatile anesthesia
Attenuate lung inflammations Immunomodulator in the patients
undergoing OLV
Protective effect on pulmonary
functionality
Reduction of inflammatory cytokines
Br J Anaesth 2007 ; 98 : 539-544
Effect of inhalation anesthesia vs Propofol
Effect of inhalation anesthesia vs Propofol
J Anesth (2015) 29:570–579
PropofolVolatile
Effect of inhalation anesthesia vs Propofol
J Anesth (2015) 29:570–579
PropofolVolatile
Effect of inhalation anesthesia vs Propofol
J Anesth (2015) 29:570–579
PropofolVolatile
OLV and Simulation
High-Fidelity Simulation of Lung Isolation With
Double-Lumen Endotracheal Tubes and Bronchial
Blockers in Anesthesiology Resident Training
Journal of Cardiothoracic and Vascular Anesthesia, Vol 28, No 4 (August), 2014: pp 865–869
High-Fidelity Simulation of Lung Isolation With
Double-Lumen Endotracheal Tubes and Bronchial
Blockers in Anesthesiology Resident Training
Journal of Cardiothoracic and Vascular Anesthesia, Vol 28, No 4 (August), 2014: pp 865–869
High-Fidelity Simulation of Lung Isolation With
Double-Lumen Endotracheal Tubes and Bronchial
Blockers in Anesthesiology Resident Training
Journal of Cardiothoracic and Vascular Anesthesia, Vol 28, No 4 (August), 2014: pp 865–869
High-Fidelity Simulation of Lung Isolation With
Double-Lumen Endotracheal Tubes and Bronchial
Blockers in Anesthesiology Resident Training
Journal of Cardiothoracic and Vascular Anesthesia, Vol 28, No 4 (August), 2014: pp 865–869
Confidence Self-Rating by Anesthesiology Residents
High-Fidelity Simulation of Lung Isolation With
Double-Lumen Endotracheal Tubes and Bronchial
Blockers in Anesthesiology Resident Training
Journal of Cardiothoracic and Vascular Anesthesia, Vol 28, No 4 (August), 2014: pp 865–869
Scores for Resident Performance During the Second Session
KFARDEBIAN
LEBANON