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Pregabalin is an anticonvulsant drug used for neuropathic pain and as an adjunct therapy for partial
seizures with or without secondary generalization in adults. Recent studies have shown that pregabalin
is effective at treating chronic pain in disorders such as fibromyalgia and spinal cord injury.
Methylcobalamin is the neurologically active form of vitamin B12. itamin B12 comes in several !inds
including hydro"y# cyano# and adenosyl# but only the methyl and adenosyl forms are active within the
body. Methylcobalamin donates methyl groups to the myelin sheath that insulates nerve fibres andregenerates damaged neurons. $n a B12 deficiency# to"ic fatty acids destroy the myelin sheath but
high enough doses of B12 can repair it. %nimal studies have shown that high doses of
Methylcobalamin are effective in neuron regeneration and that there is no !nown to"icity at these
doses.
It has been demonstrated by recent studies that combination of Pregabalin and
Methylcobalamin shows significantly better symptoms relief with the modest improvement
of nervous system, chronic pain, perioperative pain, migraine and enhances immune system
function.
$ndications and &sage'
( $t is used for neuropathic pain associated with spinal cord injury.
()iabetic peripheral neuropathy.
(*reatment of fibromyalgia.
($t is also used for treatment of chronic pain# perioperative pain# and migraine.
(+upports the nervous system
(,elps memory and learning
(Boosts energy
(,elps control homocysteine levels
(Promotes a healthy cardiovascular system
(-nhances immune system function
(-ffectively supports brain and nerve function.
)rug $nteractions'BEFOE !"#I$% !&I' ME(I)I$E !E** !&E (O)!O "BO+! "$ ME(I)"* POB*EM' "$
"**E%IE' !&"! P"!IE$! &"' $O- O &"' &"(.
&sually drug interactions occur when it is ta!en with another drug or with food. Before you ta!e a
medication for a particular ailment# you should inform the health e"pert about inta!e of any other
medications including nonprescription medications.
Mechanism of action'/ombination of Pregabalin and Methylcobalamin not only decreases the release of neurotransmitters
but also helps in regeneration of the myelin sheath. Pregabalin also has got analgesic activity which
reduces the pain associated with neuropathy. *hus the combination of Pregabalin and Methylcobalamin
is useful for arresting the progress of diabetic neuropathy and also helps in relieving the pain
associated with neuropathy. Methylcobalamin is a cofactor of methionine synthase# an enzyme that
transfers methyl groups to homocysteine to regenerate methionine. -levated homocysteine levels are
a ris! factor for coronary artery disease. Methionine can be transformed to +adeno"ylmethionine
0+%M that is involved in a variety of methylation reactions in the body# one of which is alleviating
depression.
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( )izziness
()rowsiness
()ry mouth
(/onstipation
/onclusion'From the above discussion, it can be concluded that Pregabalin and Methylcobalamin tabletcould improve the uality of life with improvement of nervous system, chronic pain,
perioperative pain, migraine and enhances immune system function and responsible for
healthy cardiovascular system.
e are ma!ing superior 7uality of Pregabalin and Methylcobalamin tablet that is used to treat brain
and nerve function and help to increase memory and learning. Cur offered tablet is processed using
high grade chemical compounds by our e"perienced 7uality controllers that ensure its 7uality# purity
and chemical properties. ,ighly treasured among the clients for its reliability# accurate composition#
e"cellent physical and purity# this tablet is offered to our esteemed clients at the mar!et leading
prices.
/ontraindications'Pregabalin is contraindicated in patients with !nown hypersensitivity to pregabalin or any of its
components. itamin B12 supplementation is generally regarded as safe during pregnancy and
lactation.
)osage'%dult' Cne /apsule daily before food or as directed by the physician.
+torage'+tore at room temperature# 1;69D / 0;8>5DE. Feep away from moisture.