nk cell melanoma
TRANSCRIPT
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8/3/2019 NK Cell Melanoma
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Gexuzen K`nnoz Lonn| `g xfo J`mnmcp maIonegmie
z`llezhm]jonn`pefmm'`x
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8/3/2019 NK Cell Melanoma
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J`mnmcp ma Gexuzen K`nnoz &GK) Lonn| &@)
Lmirz`|o ejmux 525?/ ma xmxen jnmmh npirfm`h
lonn|
Lfezelxoz`toh rfogmxpr`lennp jp xfo rzo|oglo ma
LH?1 egh xfo nelk ma LH
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8/3/2019 NK Cell Melanoma
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J`mnmcp ma Gexuzen K`nnoz Lonn| &@@)
Leg jo h`q`hoh `g xsm ie`g |ujlne||o| s`xf
h`aaozogx ovrzo||`mg rexxozg
LH?1 H`i
LH51 F`cf
LH?1 Jz`cfx
LH51 Nms-Goc
52/ ma jnmmh GKLonn| 02/ ma jnmmh GKLonn|
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8/3/2019 NK Cell Melanoma
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J`mnmcp ma Gexuzen K`nnoz Lonn| &@@@)
GK Lonn| ezo `gqmnqoh `g |oqozen rzmlo||4 Zolmcg`to egh k`nn xuimz lonn| egh q`zennp `gaolxoh lonn|
@gqmnqoh `g `iiugo |p|xoi zocunex`mg
@gqmnqoh `g egc`mcogo|`|
X`||uo fmiom|xe|`|
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8/3/2019 NK Cell Melanoma
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J`mnmcp ma Gexuzen K`nnoz Lonn| &@Q)
GK |ujlne||o| rm||o| h`aaozogx j`mnmc`l rzma`no4
Rzmn`aozex`qo zo|rmg|o xm @N:
@gxz`g|`l lpxmxmv`l lerel`xp
Elx`qex`gc`gf`j`xmzp GK zolorxmz zorozxm`zo
Ehfo|`mg imnoluno ovrzo||`mg
X`||uo fmi`gc Lpxmk`go rzmhulx`mg
Imgmk`go-Lfoimk`go zolorxmz ovrzo||`mg
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8/3/2019 NK Cell Melanoma
6/16
Gexuzen K`nnoz Lonn| egh Ionegmie
Nms k`nn`gc elx`q`xp `g q`xzm
@ire`zoh zo|rmg|o xm `gxozaozmg|
Gmx oaa`l`ogx `g fmi`gc xm ien`cgegx x`||uo|
GK)Lonn hp|auglx`mg `g ehqegloh ionegmie rex`ogx|
Mgnp aos GK)lonn| ezo amugh `g II)ioxe|xe|o|sf`lf `| rmxogx`ennp zoqoz|`jno jp xzoexiogx s`xf @N):
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8/3/2019 NK Cell Melanoma
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Iexoz`en egh Ioxfmh|
5: rex`ogx| `g ionegmie |xeco @Q s`xfmuxrzoq`mu| lfoimxfozerp
1 foenxfp hmgmz| &iexlfoh amz eco egh |ov)
Anms Lpxmioxzp egenp|`| amz h`aaozogx imnoluno|
`gqmnqoh `g xfo zocunex`mg ma GKlonn k`nn`gc egh
x`||uo fmi`gc
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8/3/2019 NK Cell Melanoma
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Elx`qex`gc Zolorxmz|GKr81
Ovrzo||oh `g zo|x`gc GK lonn|
@gqmnqoh `g ionegmie lonn k`nn`gc
N`cegh ugkgmsg
GKr88
Ovrzo||oh `g elx`qexoh GK lonn| @gqmnqoh `g ionegmie lonn k`nn`gc
N`cegh ugkgmsg
LH88 Zolorxmz amz fpenuzmg`l el`h s`xf xz`ccoz rzmrozx`o|
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8/3/2019 NK Cell Melanoma
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@gf`j`xmzp Zolorxmz|
LH6?d
@c |urozaei`np cnplmrzmxo`g| &@NX-N@Z)
\rol`a`l amz e jzmeh zegco ma FNE lne|| @ egx`cog|
GKC:E
Lxpro nolx`g cnplmrzmxo`g|
Zolmcg`to| FNEO lne|| @ cnplmrzmxo`g Amzi| foxozmh`ioz| s`xf LH08
K@Z:HN
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8/3/2019 NK Cell Melanoma
10/16
Lfoimk`go Zolorxmz|LVLZ5 Ovrzo||oh jp |oqozen ionegmie lonn n`go|
Xfo`z n`cegh| @N6 egh CZMe ezo rzmhuloh jp h`aaozogx ionegmie lonn n`go|
LV
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8/3/2019 NK Cell Melanoma
11/16
K`nn`gc Oaaolxmz Imnoluno|
Czeguno ovmlpxm|`| rexfsep
Rozamz`g Ioijzego h`|zurx`gc rzmxo`g
Czegtpio E
\oz`go rzmxoe|o
Hoexf zolorxmz rexfsep
LH0?N. LH82N. Xze`n
XGA aei`np n`cegh @gqmnqoh `g lonn xezcox ermrxm|`| |`cgen`gc
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8/3/2019 NK Cell Melanoma
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Ermrxm|`| Zonexoh Zolorxmz|
Xze`nZ:
Xzeg|ioijzego rzmxo`g s`xf lpxmrne|iex`l hmie`g lmgxe`g| ehoexf hmie`g &HH)
On`l`x eg ermrxmx`l hoexf zo|rmg|o urmg j`gh`gc ma Erm:N-XZE@N
Xze`nZ