“nhsbt strategic vision meeting” dr. les russell - october 2013 e-mail [email protected]...

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“NHSBT strategic vision meeting” Dr. Les Russell - October 2013 E-Mail [email protected] Tel +44 (0)1865 784156 www.organox.com Confidential to OrganOx Limited

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Page 1: “NHSBT strategic vision meeting” Dr. Les Russell - October 2013 E-Mail les.russell@organox.com Tel +44 (0)1865 784156  Confidential to OrganOx

“NHSBT strategic vision meeting”

Dr. Les Russell - October 2013

E-Mail [email protected] +44 (0)1865 784156www.organox.com

Confidential to OrganOx Limited

Page 2: “NHSBT strategic vision meeting” Dr. Les Russell - October 2013 E-Mail les.russell@organox.com Tel +44 (0)1865 784156  Confidential to OrganOx

Current status

Confidential to OrganOx Limited

1. Increasing donor numbers envisaged next 5 years2. Increasing ratio of DCD and ECD donors3. Increasing use of Type II donors4. Current static cold preservation techniques

Worse outcomes with prolonged cold storage Increased damage with steatotic organs No means of viability assessment

5. Decreasing use of “marginal” organs where transportation is an issue

6. Established retrieval and transplant practices in many countries

Page 3: “NHSBT strategic vision meeting” Dr. Les Russell - October 2013 E-Mail les.russell@organox.com Tel +44 (0)1865 784156  Confidential to OrganOx

“Improving the supply and quality

of organs for transplantation”

“Making untransplantable livers transplantable”

Confidential to OrganOx Limited : Copyright © OrganOx Limited

Page 4: “NHSBT strategic vision meeting” Dr. Les Russell - October 2013 E-Mail les.russell@organox.com Tel +44 (0)1865 784156  Confidential to OrganOx

Designed by transplant surgeons for transplant surgeons

Confidential to OrganOx Limited : Copyright © OrganOx Limited

Page 5: “NHSBT strategic vision meeting” Dr. Les Russell - October 2013 E-Mail les.russell@organox.com Tel +44 (0)1865 784156  Confidential to OrganOx

Issues and trends through the next 5 years

Confidential to OrganOx Limited

1. Increased use of organs from elderly donors

2. Increased use of organs from further obese and ECD patients

3. Increasing pressure on transplant surgeons and teams to operate at unsocial hours

4. Greater logistical challenges

5. New technology needs justification

6. Potential for interventions to improve outcomes

Page 6: “NHSBT strategic vision meeting” Dr. Les Russell - October 2013 E-Mail les.russell@organox.com Tel +44 (0)1865 784156  Confidential to OrganOx

Confidential to OrganOx Limited

1. Increased use of organs from elderly donors

2. Increased use of organs from further obese and ECD patients

3. Increasing pressure on transplant surgeons and teams to operate at unsocial hours

4. Greater logistical challenges

5. New technology needs justification

6. Potential for interventions to improve outcomes

Issues and trends through the next 5 years

Page 7: “NHSBT strategic vision meeting” Dr. Les Russell - October 2013 E-Mail les.russell@organox.com Tel +44 (0)1865 784156  Confidential to OrganOx

Issues and trends through the next 5 years

Confidential to OrganOx Limited

1. Increased use of organs from elderly donors

2. Increased use of organs from further obese and ECD patients

3. Increasing pressure on transplant surgeons and teams to operate at unsocial hours

4. Greater logistical challenges

5. New technology needs justification

6. Potential for interventions to improve outcomes

Page 8: “NHSBT strategic vision meeting” Dr. Les Russell - October 2013 E-Mail les.russell@organox.com Tel +44 (0)1865 784156  Confidential to OrganOx

Issues and trends through the next 5 years

Confidential to OrganOx Limited

1. Increased use of organs from elderly donors

2. Increased use of organs from further obese and ECD patients

3. Increasing pressure on transplant surgeons and teams to operate at unsocial hours

4. Greater logistical challenges

5. New technology needs justification

6. Potential for interventions to improve outcomes

Page 9: “NHSBT strategic vision meeting” Dr. Les Russell - October 2013 E-Mail les.russell@organox.com Tel +44 (0)1865 784156  Confidential to OrganOx

Issues and trends through the next 5 years

Confidential to OrganOx Limited

1. Increased use of organs from elderly donors

2. Increased use of organs from further obese and ECD patients

3. Increasing pressure on transplant surgeons and teams to operate at unsocial hours

4. Greater logistical challenges

5. New technology needs justification

6. Potential for interventions to improve outcomes

Page 10: “NHSBT strategic vision meeting” Dr. Les Russell - October 2013 E-Mail les.russell@organox.com Tel +44 (0)1865 784156  Confidential to OrganOx

Issues and trends through the next 5 years

Confidential to OrganOx Limited

1. Increased use of organs from elderly donors

2. Increased use of organs from further obese and ECD patients

3. Increasing pressure on transplant surgeons and teams to operate at unsocial hours

4. Greater logistical challenges

5. New technology needs justification

6. Potential for interventions to improve outcomes

Page 11: “NHSBT strategic vision meeting” Dr. Les Russell - October 2013 E-Mail les.russell@organox.com Tel +44 (0)1865 784156  Confidential to OrganOx

Issues and trends through the next 5 years

Confidential to OrganOx Limited

1. Increased use of organs from elderly donors

2. Increased use of organs from further obese and ECD patients

3. Increasing pressure on transplant surgeons and teams to operate at unsocial hours

4. Greater logistical challenges

5. New technology needs justification

6. Potential for interventions to improve outcomes

Page 12: “NHSBT strategic vision meeting” Dr. Les Russell - October 2013 E-Mail les.russell@organox.com Tel +44 (0)1865 784156  Confidential to OrganOx
Page 13: “NHSBT strategic vision meeting” Dr. Les Russell - October 2013 E-Mail les.russell@organox.com Tel +44 (0)1865 784156  Confidential to OrganOx
Page 14: “NHSBT strategic vision meeting” Dr. Les Russell - October 2013 E-Mail les.russell@organox.com Tel +44 (0)1865 784156  Confidential to OrganOx
Page 15: “NHSBT strategic vision meeting” Dr. Les Russell - October 2013 E-Mail les.russell@organox.com Tel +44 (0)1865 784156  Confidential to OrganOx

Summary

Confidential to OrganOx Limited

1. Desperate need to increase organ availability

2. Increasing use of marginal organs

3. Need for assessment of organ viability

4. Believe that NMP can make untransplantable organs transplantable Increases organ availability Improves patient outcomes and saves lives