new postgraduate research in biomedical engineering · 2018. 8. 28. · the computational and...

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The Computational and Medical Chemistry Laboratory (CMCL) is located within the Department of Biomedical Engineering, Faculty of Engineering, King Mongkut's Institute of Technology Ladkrabang. Our research interests lie in the Pharmaceutical Engineering field, a multi-disciplinary area that encompasses Chemistry, Physics, Biochemistry, Biology, Engineering & Medicine. M.Eng. and Ph.D. positions are available in Biomedical Engineering at KMITL. Applications from B.Eng., B.Sc., M.Eng. and M.Sc. students with a background in Chemical Engineering, Chemistry or Physical Sciences are sought. Funding is available to cover living expenses and associated research costs. If you are interested in a career in Biomedical Engineering then please get in touch to see how research with us can help you achieve your aim. Postgraduate Research in Biomedical Engineering N=141 [Conc, nM per 1 Mg/Kg dose] Low potency Poor exposure High potency Good exposure High potency Poor exposure > 300 mg 100 mg 30 mg 10 mg < 1 mg Dose Low potency Good exposure Statistically analyze the vast amount of data on drugs and development compounds to help understand the origin of success and failures in drug discovery. 4. Cheminformatics 3. Molecular Modelling Simulate the reaction mechanisms of proteins, computationally - design new compounds for synthesis using on ligand based and structure based design methods. 2. Physical Chemistry & Biochemical Sensors Develop biosensors for medical and environment use. Assess the drug physical properties to gain understanding of the origin of activity in disease/target based bioassay results. b N O Br S N O Br NH N O NH R 2 N O S a a b 11 12 R 1 R 1 R 2 13 14 (a) m-CPBA, DCM, 12-62%; (b) Pd(PPh 3 ) 4 , Na 2 CO 3 , N 2 , 5-56%. 1. Drug Design / Synthesis Design and synthesize new compounds to help treat diseases of the developing world including malaria, cancer and TB. www.bme-cmcl.weebly.com/ Research Scholarships We have fully funded M.Eng. and Ph.D. positions available. If you are interested in one of our research themes then we would love to hear from you. If you have or are expecting to graduate with a B.Eng., B.Sc., M.Eng. or M.Sc. then please get in touch with us to discuss our research opportunities. MSc Scholarships: 8-10,000 baht per month PhD Scholarships: 10-12,000 baht per month Postdoctoral Positions: 30-35,000 baht per month Graduates of the program will gain critical skills leading to employment opportunities in the pharmaceutical and biotechnology industry in Thailand and abroad. Website Please see our website for further details or contact us directly via email or telephone. Contact Us Dr. M. Paul Gleeson (English language contact) Biomedical Engineering, Faculty of Engineering Email: [email protected] Tel: 0869779678 Assoc. Prof. Duangkamol Gleeson (English language contact) Department of Chemistry, Faculty of Science Email: [email protected], Tel: 0816077000

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Page 1: New Postgraduate Research in Biomedical Engineering · 2018. 8. 28. · The Computational and Medical Chemistry Laboratory (CMCL) is located within the Department of Biomedical Engineering,

The Computational and Medical Chemistry Laboratory (CMCL) is located within the Department of BiomedicalEngineering, Faculty of Engineering, King Mongkut's Institute of Technology Ladkrabang. Our research interests lie inthe Pharmaceutical Engineering field, a multi-disciplinary area that encompasses Chemistry, Physics, Biochemistry,Biology, Engineering & Medicine.

M.Eng. and Ph.D. positions are available in Biomedical Engineering at KMITL. Applications from B.Eng., B.Sc., M.Eng.and M.Sc. students with a background in Chemical Engineering, Chemistry or Physical Sciences are sought. Funding isavailable to cover living expenses and associated research costs. If you are interested in a career in BiomedicalEngineering then please get in touch to see how research with us can help you achieve your aim.

Postgraduate Research in Biomedical

Engineering

N=141

[Conc, nM per 1 Mg/Kg dose]

Low potencyPoor exposure

High potencyGood exposure

High potencyPoor exposure

> 300 mg

100 mg

30 mg

10 mg

< 1 mg

Dose

Low potencyGood exposure

Statistically analyze the vast amount of data on drugs and development compounds to help understand the origin of

success and failures in drug discovery.

4. Cheminformatics3. Molecular Modelling

Simulate the reaction mechanisms of proteins, computationally -design new compounds for synthesis using on ligand based and

structure based design methods.

2. Physical Chemistry & Biochemical Sensors

Develop biosensors for medical and environment use. Assess the drug physical properties to gain understanding of the origin of

activity in disease/target based bioassay results.

b

N

O

Br

S

N

O

Br

NH

N

O

NH

R2

N

O

S

a

a

b

11 12

R1

R1

R2

13 14

(a) m-CPBA, DCM, 12-62%; (b) Pd(PPh3)4, Na2CO3, N2, 5-56%.

1. Drug Design / Synthesis

Design and synthesize new compounds to help treat diseases of the developing world including malaria, cancer and TB.

www.bme-cmcl.weebly.com/

Research ScholarshipsWe have fully funded M.Eng. and Ph.D. positions available. If you areinterested in one of our research themes then we would love to hearfrom you. If you have or are expecting to graduate with a B.Eng., B.Sc.,M.Eng. or M.Sc. then please get in touch with us to discuss ourresearch opportunities.

• MSc Scholarships: 8-10,000 baht per month

• PhD Scholarships: 10-12,000 baht per month

• Postdoctoral Positions: 30-35,000 baht per month

Graduates of the program will gain critical skills leading toemployment opportunities in the pharmaceutical and biotechnologyindustry in Thailand and abroad.

Website

Please see our website for further details or contact us directly via email or telephone.

Contact Us

• Dr. M. Paul Gleeson (English language contact)

• Biomedical Engineering, Faculty of Engineering

• Email: [email protected] Tel: 0869779678

• Assoc. Prof. Duangkamol Gleeson (English language contact)

• Department of Chemistry, Faculty of Science

• Email: [email protected], Tel: 0816077000