new hod’s message - bch.nus.edu.sg · ms nurfadillah bte mahmood management assistant officer –...

18
Inside this issue Congratulations! ............ 2 PG Students ................... 4 New Staff ....................... 6 Grants Awarded ............. 8 Publications ................... 9 Recent Events ................ 11 Do you know? ................ 17 Baby News ..................... 18 Bon Voyage ................... 18 Important Dates 29/06 PhD Oral Defense Valentina Migliori 08/07 Commencement (Medicine PG Students) 06/08 PhD Oral Defense Goh Shijie New HOD’s message Professor Jean Paul THEIRY I am extremely pleased to preface this quarterly edition of Biochem Buzz. As the new HOD, I would like to thank everyone for their very warm welcome; my task will be much easier in a friendly and collegial atmosphere. This internal newsletter is one of the ways in which we can disseminate information on the life of the Depart- ment. Clearly, once again, the Department shows its strength within the YLL SOM and beyond. I mentioned during my recruitment presentation that I will discuss in depth, the research and teaching with all faculty members. I will soon start this process, together with A/P Marie Veronique Clement, our new Deputy Head. I have also suggested that the Department may benefit from the sup- port of a scientific editor; I hope this will soon become a reality. My main mission will be to provide impetus leveraging on existing programs that will create exciting new research with the potential to be published in high-impact factor journals and to attain grant sup- port. I am open to suggestions from everyone. I would also like to state on record my appreciation and thanks to A/P Tan Tin Wee and A/P Maxey Chung for their leadership in the past year. They are certainly valued members of the Department. Biochemistry Buzz Volume 14, May 2012

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Page 1: New HOD’s message - bch.nus.edu.sg · Ms Nurfadillah Bte Mahmood Management Assistant Officer – Education Supervisor: Ms Aniza A. Wahid Assumed Duty: 26 March 2012 Mr Muhammad

Inside this issue

Congratulations! ............ 2

PG Students ................... 4

New Staff ....................... 6

Grants Awarded ............. 8

Publications ................... 9

Recent Events ................ 11

Do you know? ................ 17

Baby News ..................... 18

Bon Voyage ................... 18

Important Dates

29/06 PhD Oral Defense Valentina Migliori

08/07 Commencement (Medicine PG Students)

06/08 PhD Oral Defense Goh Shijie

New HOD’s message Professor Jean Paul THEIRY

I am extremely pleased to preface this

quarterly edition of Biochem Buzz. As

the new HOD, I would like to thank

everyone for their very warm welcome; my

task will be much easier in a friendly and

collegial atmosphere.

This internal newsletter is one of the ways

in which we can disseminate information on the life of the Depart-

ment. Clearly, once again, the Department shows its strength within

the YLL SOM and beyond.

I mentioned during my recruitment presentation that I will discuss in

depth, the research and teaching with all faculty members. I will

soon start this process, together with A/P Marie Veronique Clement,

our new Deputy Head.

I have also suggested that the Department may benefit from the sup-

port of a scientific editor; I hope this will soon become a reality.

My main mission will be to provide impetus leveraging on existing

programs that will create exciting new research with the potential to

be published in high-impact factor journals and to attain grant sup-

port. I am open to suggestions from everyone.

I would also like to state on record my appreciation and thanks to A/P Tan Tin Wee and A/P Maxey Chung for their leadership in the past year. They are certainly valued members of the Department.

Biochemistry Buzz Volume 14, May 2012

Page 2: New HOD’s message - bch.nus.edu.sg · Ms Nurfadillah Bte Mahmood Management Assistant Officer – Education Supervisor: Ms Aniza A. Wahid Assumed Duty: 26 March 2012 Mr Muhammad

A/P Tan Tin Wee

He won the Global Connectors Award (Recognizing individuals from around the world who have made significant

contributions to the global growth and use of the internet) and inducted into the Hall of Fame 2012 Inductees. The

ceremony was held on 23 April 2012 at the

Internet Society's Global INET 2012 confer-

ence in Geneva, Switzerland.

He was featured in the Straits Times, Sunday

29 April 2012 for his recognition and contri-

bution in the internet field.

A/P Tan is Program Committee Member of

the International Symposium on Network

Enabled Health Informatics, Bio-Medicine

and Bioinformatics (HI-BI-BI 2012) to be

held on 27-28 August 2012 in Istanbul.

He is also member of iJAM Expert Panel

(Media Development Authority, the Interac-

tive Digital Media Programme Office – IDMPO) to provide guidance and reviews for projects.

A/P Tan is appointed as member of Scientific Advisory Committee of the Program on Bioinformatics – the Philip-

pine Genome Center.

He is also a member of the 2012 InCoB International Advisory Committee for the official conference of Asia-

Pacific Bioinformatics Network to be held 3-5 October 2012, Bangkok, Thailand.

A/P Tan was involved in the Singapore-Japan High Performance Computing Workshop which was held on 27-28

February 2012 at Grand Copthorne Waterfront.

Biochemistry Buzz ~2~ Volume 14, May 2012

A/P Chang Chan Fong

A/P Chang will be coordinating a new Life Sciences Module LSM3264 “Environmental Biochemistry” which will

start in Semester 2 AY2012/2013.

A/P Markus Wenk

A/P Wenk and his team’s development of new methodology for detecting TB using novel TB biomarkers and

their collaboration with the Foundation for Innovative New Diagnostics (FIND) aiming to translate these targets

into a diagnostic test that is affordable, easy to use and produces rapid results and can be used by community

health workers in poor countries was reported in The Straits Times 15 December 2011 issue.

A/P Wenk is the organizer of the 4th International Singapore Lipid Symposium which was held on March 13–16

2012.

A/P Chung Ching Ming, Maxey

A/P has been re-appointed as Country/Region Advisor for Australia/New Zealand at the International Relations

Office from 1 April 2012 to 31 March 2013.

He has been elected to the membership of the NUS Senate Delegacy from 1 July 2012 to 30 June 2014.

CONGRATULATIONS! - STAFF

Page 3: New HOD’s message - bch.nus.edu.sg · Ms Nurfadillah Bte Mahmood Management Assistant Officer – Education Supervisor: Ms Aniza A. Wahid Assumed Duty: 26 March 2012 Mr Muhammad

A/P Too Heng-Phon

A/P Too’s patents on “An Integrated Solid Phase Extraction Coupled Ultra-Performance Liquid Chromatography-

Mass Spectrometry (SPE-UPLC-MS) Method for the Profiling of DXP Metabolites and System Diagnostics of

DXP Pathway” and “Analyte-specific spatially addressable nanostructure array (ASANA) – integrated Si nanowires

with microfluidics for enhancement of analytes capture” were filed as the US provisional application on 12 March

2012.

A/P Lee Guat Lay, Caroline

A/P Lee’s recent outstanding publication titled “An update on ABCB1 pharmacogenetics: insights from a 3D

model into the location and evolutionary conservation of residues corresponding to SNPs associated with drug

pharmacokinetics” in The Pharmacogenomics Journal was well accessed with over 1000 hits within first month of

release.

Dr Lim Yoon Pin

PCT (Patent Cooperation Treaty) filed for his invention on “novel cancer target and biomarker.”

Dr Lim’s provisional patent filed for “discovery of novel breast cancer metastasis effectors using phosphoprote-

omics” is in progress.

He is appointed as SERI Adjunct Senior Research Scientist from 1 February 2012 for a period of 3-years.

Dr Lim’s proposal for a symposium on Translational and Clinical Research in the Industry has been approved by

YLL SOM Dean’s office and will be rolled out in Semester 1 AY2012/2013.

He was an invited speaker for the A*STAR – China Ministry of Science & Technology (MOST) Joint Symposium

on Biological Sciences, 13-14th March 2012.

Dr Wu Qiang

Dr Wu will be coordinating a new Life Sciences Module LSM4245 “Epigenetics and Chromatin Biology” which

will start in Semester 1 AY2012/2013.

Adjunct Assistant Professor Dr Tong Joo Chuan, Victor

Dr Tong is honoured as one of the World Economic Forum (WEF) Young Leaders amongst four young profes-

sionals from Singapore. The news was released in the Straits Times on 7 March 2012.

Ms Sha Lanjie and Ms Qian Feng

Congratulations to Ms Sha Lanjie and Ms Qian Feng for winning the NUHS Values-In-Action (VIA) 2012

individual award.

A/P Gan Yunn Hwen

A/P Gan was featured in the Straits Times and LianHe Zaobao on Thursday 3 May 2012, for her team’s research

findings on patients with Type 2 diabetes lacking a molecule impairing efforts to kill unwanted bacteria. Her re-

search paper was published in The Journal of Clinical Investigation.

A/P Caroline Lee and Dr Kenneth Ban

A/P Caroline Lee and Dr Kenneth Ban served as judges during the Singapore Science & Engineering Fair held

from 7 to 8 March 2012. Their commitment and expertise were deeply appreciated by the Ministry of Education.

Biochemistry Buzz ~3~ Volume 14, May 2012

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Mr Lum Fok-Moon (Supervisor: A/P Tan Tin Wee and AP Ng Fong Poh Lisa)

Awarded the NUS Merlion Fellowship 2011 which is a France-Singapore research project and

funded for 3 years.

CONGRATULATIONS! - STUDENTS

Ms Hou Qian (Supervisor: A/P Chung Ching Ming, Maxey)

She is one of the recipients of the Best 10 Poster Presentation Award ($100 Cash + Certificate of

Award) at YLLSOM 2nd Annual Graduate Scientific Congress 2012 held on 15 February 2012 at

NUHS Tower Block.

Ms Wu Wei (Supervisor: A/P Chung Ching Ming, Maxey)

Wu Wei is one of the recipients of the Best 10 Poster Presentation Award ($100 Cash + Certificate

of Award) at YLLSOM 2nd Annual Graduate Scientific Congress 2012 held on 15 February 2012

at NUHS Tower Block.

She is also one of the recipients for the Young Travel Scientist Award in the 6th AOHUPO

Congress in Beijing.

Mr Lin Qifeng (Supervisor: A/P Chung Ching Ming, Maxey )

Lin Qifeng is one of the recipients for the Young Travel Scientist Award in the 6th AOHUPO

Congress in Beijing.

Mr Lee Seow Chong (Supervisor: A/P Chung Ching Ming, Maxey )

Lee Seow Chong is one of the recipients for the Young Travel Scientist Award in the 6th AOHUPO

Congress in Beijing.

Ms Valentina Migliori (Supervisor: Adjunct Assistant Professor Dr Ernesto Guccione)

She is one of the recipients of the Top 3 Best Research Publication Award ($200 Cash Prize each)

at YLLSOM 2nd Annual Graduate Scientific Congress 2012 held on 15 February 2012 at NUHS

Tower Block.

Biochemistry Buzz Volume 14, May 2012 Biochemistry Buzz ~4~ Volume 14, May 2012

Page 5: New HOD’s message - bch.nus.edu.sg · Ms Nurfadillah Bte Mahmood Management Assistant Officer – Education Supervisor: Ms Aniza A. Wahid Assumed Duty: 26 March 2012 Mr Muhammad

Ms Sugunavathi Sepramaniam (Supervisor: Professor Jeyaseelan, Kandiah)

Presented her research findings at the 1st NKF Scientific meeting held on Saturday, 4 February 2012 and received

the 1st prize for her oral presentation from a panel of judges including our NUS President as the Chairman.

She is the recipient of the Chua Toh Hua Memorial Gold Medal for AY2011/2012 for being the Best Doctor of

Doctor of Philosophy graduate with the most outstanding research work done in Life Sciences.

Student’s Conferment Congratulations to the following students on the conferment of their postgraduate degrees. Well done!

Biochemistry Buzz Volume 14, May 2012 Biochemistry Buzz ~5~ Volume 14, May 2012

Name Supervisor Prog Month of

Conferment

Mr Lau Siang Lin A/P Chung Ching Ming,

Maxey MSc December 2011

Ms Sugunavathi D/O Sepramaniam Prof Jeyaseelan, Kandiah PhD January 2012

Ms Benny Paula-Beth Angelica

Tiqui A/P Michael Raghunath MSc January 2012

Ms Lim Shen Jean A/P Tan Tin Wee MSc January 2012

Mr Cheng Fei Dr Deng Lih Wen PhD February 2012

Mr Loei Hendrick A/P Chung Ching Ming,

Maxey MSc February 2012

Mr Goh Teck Wah William Prof Hong Wanjin PhD March 2012

Page 6: New HOD’s message - bch.nus.edu.sg · Ms Nurfadillah Bte Mahmood Management Assistant Officer – Education Supervisor: Ms Aniza A. Wahid Assumed Duty: 26 March 2012 Mr Muhammad

Adjunct Faculty

New Staff Welcome to the family

Professor Hui Kam Man

Appointment: Adjunct Professor

Principal Investigator & Head, Division of Cellular & Molecular Research, NCC

Assumed Duty: 5 March 2012

Lab Executives

Mr Chow Kean Pang

Supervisor: Prof Fu Xin-Yuan

Assumed Duty: 5 December 2011

Ms Soh Yan Ling Melissa

Supervisor: A/P Chua Kim Lee

Assumed Duty: 26 January 2012

Ms Ooi Pei Kun

Supervisor: Dr Kenneth Ban

Assumed Duty: 3 February 2012

Ms Hou Peiling

Supervisor: Dr Lim Yoon Pin

Assumed Duty: 22 December 2011

Research Fellow

Biochemistry Buzz ~6~ Volume 14, May 2012

A/P Robinson Robert Charles

Appointment: Adjunct Associate Professor

Associate Professor and Principal Investigator, Institute of Molecular and Cell Biology

Assumed Duty: 1 January 2012

Page 7: New HOD’s message - bch.nus.edu.sg · Ms Nurfadillah Bte Mahmood Management Assistant Officer – Education Supervisor: Ms Aniza A. Wahid Assumed Duty: 26 March 2012 Mr Muhammad

Research Assistants

Ms Fanny Ng

Supervisor: A/P Tang Bor Luen

Assumed Duty: 31 October 2011

Mr Khanh Phuong Dang

Supervisor: A/P Markus R Wenk

Assumed Duty: 5 January 2012

Ms Khing Suu Suu Aung

Supervisor: Dr Deng Lih Wen

Assumed Duty: 24 February 2012

Mr Koh Yong Qin

Supervisor: Dr Yeong Foong May

Assumed Duty: 15 February 2012

Ms Tay Zoey

Supervisor: Dr Chen Ee Sin

Assumed Duty: 1 March 2012

Ms Liu Jie

Supervisor: Dr Deng Lih Wen

Assumed Duty: 13 January 2012

Mr Lee Wei Ren

Supervisor: Dr Yeong Foong May

Assumed Duty: 21 February 2012

Ms Geng Wei

Supervisor: A/P Tan May Chin, Theresa

Assumed Duty: 6 March 2012

Ms Kim Ji Hyun

Supervisor: Prof Fu Xin-Yuan

Assumed Duty: 6 April 2012

Non-Academic

Ms Nurfadillah Bte Mahmood

Management Assistant Officer – Education

Supervisor: Ms Aniza A. Wahid

Assumed Duty: 26 March 2012

Mr Muhammad Irwan Bin Karno

Management Assistant Officer – Human Resource

Supervisor: Ms Aniza A. Wahid

Assumed Duty : 26 March 2012

Biochemistry Buzz ~7~ Volume 14, May 2012

Page 8: New HOD’s message - bch.nus.edu.sg · Ms Nurfadillah Bte Mahmood Management Assistant Officer – Education Supervisor: Ms Aniza A. Wahid Assumed Duty: 26 March 2012 Mr Muhammad

Grants Awarded

Month Principal

Investigator Amount Project title Source of Fund

January 2012

Dr Yew Wen Shan $179,500

Biosynthesis of Anti-Ageing Therapeutics via

Synthetic Polyketide Enzymology Tier 1 FRT

Dr Long Yun Chau $162,200

Role of insulin-induced glycolysis in the reg-

ulation of PGC1α-mediated myotube lipid

metabolism MOE Tier 1

February 2012

Prof Sit Kim Ping $180,000

Loss of UCP2 in clear cell Renal Cell carcino-

ma (ccRCC) Tier 1 FRT

A/P Caroline Lee $440,100

SERC Joint Diagnostic Grant (Collaboration

with NCC) Development of a tool to predict

response of a patients to Fluorouracil/

Platinum drugs

BMRC-SERC Diagnostics

Joint Grant

A/P Too Heng-Phon $46,000

Development of paclitaxel precursor high

project title : producing strains of GRAS Bac-

terium Bacillus subtilis

SMART Singapore-MIT

Alliance for Research and

Technology

March 2012

A/P Theresa Tan $84,300

Role of microRNAs in metastasis of hepato-

cellular carcinoma MOE AcRF Tier 1

A/P Tang Bor Luen $84,300

Delinating molecular mechanisms underly-

ing the cellular dynamics and neuritogenic

role of a neuron-enriched Ig superfamily cell

adhesion molecule MOE AcRF Tier 1

A/P Theresa Tan $100,000 MicroRNA as biomarkers for bladder cancer NUHS Bench-to-Bedside

Dr Deng Lih Wen $100,000

Development and Application of Epithelial

Mesenchymal Transition Component Genes

as a Discovery Tool for Novel Therapeutics:

A Quest for personalized Medicine in Epithe-

lial Ovarian Cancer

NUHS Bench-to-Bedside

A/P Tang Bor Luen $100,000

Levels and activities of sirtuins in peripheral

blood cells as biomarkers for healthy ageing

and ageing disorders.

NUHS Bench-to-Bedside

A/P Markus Wenk $531,588

Biomarkers in Tuberculosis : Lipid-Specific

Immune Response

BMRC-SERC Diagnostics

Joint Grant

Biochemistry Buzz ~8~ Volume 14, May 2012

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Publications 1. Suresh*, K P, J. Gruber, L F NG, B Halliwell and R. Gunawan, "Maximizing signal-to-noise ratio in the random mutation cap-

ture assay." Nucleic Acids Research, (2011). (United Kingdom). (Epub; PMID: 22180539; Updated: 13 Jan 2012).

2. Anbalagan M, Sabapathy K., “JNK1 and JNK2 play redundant functions in Myc-induced B cell lymphoma formation.” Int J

Cancer. 2012 Apr 15;130(8):1967-9

3. Sugunavathi, D S, A Armugam, EM Wintour and K Jeyaseelan*, "MicroRNA 130a represses transcriptional activity of Aqua-

porin 4 promoter". Journal of biological Chemistry, 287 (2012): 12006-12015. (United States).

4. Karthikeyan, C, K Setyowati, D S Sugunavathi, A Armugam, Wintour EM, Bertram JF and K Jeyaseelan*, "Role of mi-

croRNAs in kidney homeostasis and disease". Kidney International, (2012). (United States). (PMID:22237749, epub ahead of

print. Updated on 23.02.12).

5. Messerschmidt DM, de Vries W, Ito M, Solter D, Ferguson-Smith A, Knowles BB. “Trim28 is required for epigenetic stability

during mouse oocyte to embryo transition. Science 2012 Mar 23; 335(6075):1499-502.

6. Goh*, W B W, YH Lee, Z Ramdzan, MJ Sergot, M C M Chung and L Wong, "Proteomics Signature Profiling (PSP): A novel

contextualization approach for cancer proteomics". Journal of Proteome Research, 11, no. 3 (2012): 1571-1581. (United

States).

7. WW*, Goh, Lee YH, M C M Chung and L Wong, "How advancement in biological network analysis methods empowers pro-

teomics". Proteomics, 12, no. 4-5 (2012): 550-563. (Germany). (PMID: 22247042, updated 6.05.12).

8. Tan, H T, W Wu, Ng YZ, Zhang X, Yan B, Ong CW, Tan S, Salto-Tellez M, S C Hooi and M C M Chung*, "Proteomic Analysis

of Colorectal Cancer Metastasis: Stathmin-1 Revealed as a Player in Cancer Cell Migration and Prognostic Marker". Journal of

Proteome Research, 11, no. 2 (2012): 1433-45. (United States). (PMID: 22181002;Epub ahead of print; updated on 02.03.2012).

9. Loei, H, H T Tan, T K Lim, KH Lim, B Y J SO, K G Yeoh and M C M Chung, "Mining the Gastric Cancer Secretome: Identifica-

tion of GRN as a Potential Diagnostic Marker for Early Gastric Cancer." Journal of Proteome Research, 11, no. 3 (2011): 1759-

72. (United States). (Epub; PMID: 22204653; Updated: 13 Jan 2012).

10. Kam YK, Lum FM, Teo TH, Lee WWL, Simarmata D, Harjanto D, Chua CL, Chan YF, Wee JK, Chow A, Lin RTP, Leo YS, Le

Grand R, Sam IC, Tong JC, Roques P, Wiesmüller KH, Rénia L, Rötzschke R, Ng LFP , “Early neutralizing IgG3 response to

Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein” EMBO Mol Med 2012 Apr;4

(4):330-43.

11. Kam YW, Simarmata D, Chow A, Her Z, Teng TS, Ong EKS, Rénia L, Leo YS, Ng LFP “Early Appearance of Neutralizing IgG3-

antibodies is associated with Chikungunya Virus Clearance and Long-term Clinical Protection” J Infect Dis 2012 Apr; 205

(7):1147-54.

12. Wee LJK, Lim SJ, Ng LFP, JC Tong (2012) “Immunoinformatics: how in silico methods are re-shaping the investigation of

immune specificity” Front Biosci (Elite Ed). 2012 Jan 1;4:311-9.

13. Chen, Y, HH Hor And B L Tang*, "AMIGO is expressed in multiple brain cell types and may regulate dendritic growth and

neuronal survival." Journal Of Cellular Physiology, 227, no. 5 (2012): 2217-2229. (United States). (PMID: 21938721, [Epub

ahead of print], updated as at 6.10.2011).

Biochemistry Buzz ~9~ Volume 14, May 2012

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14. Tan, SH, G Shui, J Zhou, JJ Li, BH Bay, M R Wenk and H M Shen, "Induction of autophagy by palmitic acid via a PKC-mediated

signalling pathway independent of mTOR." Journal Of Biological Chemistry, (2012). (United States). (Epub; PMID 22408252; Up-

dated: 10 Apr 2012).

15. Mathuru, AS, C Kibat, W F Cheong, G Shui, M R Wenk, RW Friedrich and S Jesuthasan,"Chondroitin Fragments Are Odorants that

Trigger Fear Behavior in Fish." Current Biology, 22, no. 6 (2012): 538-44. (United States). (PMID: 22365850; Updated: 10 Apr 2012).

16. Rodriguez-Navarro, JA, S Kaushik, H Koga, C Dall'armi, G Shui, M R Wenk, G Di Paolo and AM Cuervo, "Inhibitory effect of dietary

lipids on chaperone-mediated autophagy." Proceedings of the National Academy of Sciences of the United States of America, 109,

no. 12 (2012): E705-14. (United States). (PMID: 22331875; Updated: 10 Apr 2012).

17. Sundaram, JR, ES Chan, P P CHARLENE, TK Pareek, W F CHEONG, G Shui, N Tang,CM Low, M R Wenk and S Kesavapany,

"Cdk5/p25-induced cytosolic PLA2-mediated lysophosphatidylcholine production regulates neuroinflammation and triggers neu-

rodegeneration." Journal of Neuroscience, 32, no. 3 (2012): 1020-34. (United States). (PMID: 22262900; Updated: 10 April 2012).

18. Wang, W, N Lv, S Zhang, G Shui, H Qian, J Zhang, Y Chen, J Ye, Y Xie, Y Shen, M R Wenk and P Li, "Cidea is an essential transcrip-

tional coactivator regulating mammary gland secretion of milk lipids." Nature Medicine, 18, no. 2 (2012): 235-43. (United States).

(PMID: 22245780; Updated: 10 Apr 2012).

19. Jeyapriya, R S, H H E S Chan, C P Poore, Tej K Pareek, W F Cheong, G Shui, N Tang, C M Low, M R Wenk and S Kesavapany*,

"p25/Cdk5 induced cytosolic PLA2-mediated lysophosphatidylcholine production regulates neuroinflammation and triggers neu-

rodegeneration". Journal of Neuroscience, 32, no. 3 (2012). (United States).

20. 13. Chiow, KH, Y Tan, RY Chua, D Huang, ML Ng, T T Federico, M R Wenk and SH Wong, "SNX3-dependent regulation of epider-

mal growth factor receptor (EGFR) trafficking and degradation by aspirin in epidermoid carcinoma (A-431) cells." CMLS-Cellular

and Molecular Life Sciences, (2011). (Switzerland). (Epub; PMID: 22159558; Updated: 17 Jan 2012).

21. 14. Chan, RB, TG Oliveira, EP Cortes, LS Honig, KE Duff, SA Small, M R Wenk, G Shui and G Di Paolo, "Comparative lipidomic

analysis of mouse and human brain with Alzheimer's disease ." Journal Of Biological Chemistry, (2011). (United States). (PMID:

22134919; updated: 17 Jan 2012).

22. Wanpen, P and T Hagen, "Characterization of the Cullin7 E3 ubiquitin ligase-heterodimerization of cullin substrate receptors as a

novel mechanism to regulate cullin E3 ligase activity". Cellular Signalling, 24, no. 1 (2012): 290-5. (United States). (PMID:

21946088; updated on 13.01.2012).

23. Choo, YY, B K Boh, Lou JJ, Eng J, Leck YC, Anders B, Smith PG and T Hagen, "Characterization of the role of COP9 signalosome in

regulating cullin E3 ubiquitin ligase activity". Molecular Biology of the Cell, 22, no. 24 (2011): 4706-15. (United States).

(PMID:22013077; updated on 13.01.2012).

24. Mukherjee, M, CSY Chow SY, YP Yusoff P, SJ Seetharaman J, CN Cherlyn Ng, SS Sinniah Saravanan, XWK Xiao Woon Koh, NFMA

Nur Farehan M. Asgar, LD Dan Li, DY Daniel Yim, RAJ Rebecca A. Jackson, JY Jingxi Yew, JQ Jingru Qian, AI Audrey Iyu, Y P Lim,

X Zhou, NS Newman Sze, GG Graeme Guy and J Sivaraman, "Structure of a novel phosphotyrosine-binding domain in Hakai that

targets E-cadherin". EMBO Journal, 31, no. 5 (2012): 1308-19. (United States).

25. 13. Sanbhnani, S and F M Yeong*, "CHFR: a checkpoint protein implicated in cancers". CMLS-Cellular and Molecular Life Sciences,

(2011). (Switzerland).

Biochemistry Buzz ~10~ Volume 14, May 2012

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Biochemistry Buzz ~11~ Volume 14, May 2012

Recent Events

Special Guest Speaker at Research in Progress Seminar on

2 February 2012 at MD7, Seminar Room M9

Upon invitation by Dr Thilo Hagen, CEO of 1st Base Company, Mr Lee Kok Choy (Alumni of Department of Biochemistry) gave an inspirational talk on his path to success as well as his company. Mr Lee’s sharing was very well received by many students and some quotable quotes from his talk are: 1) Never over-promise, always over-deliver 2) Quality, first and foremost 3) Always have fun in what we are doing while continuing to be able to exceed our customers' requirements 4) There will always be problems in life, just work around it/them

Page 12: New HOD’s message - bch.nus.edu.sg · Ms Nurfadillah Bte Mahmood Management Assistant Officer – Education Supervisor: Ms Aniza A. Wahid Assumed Duty: 26 March 2012 Mr Muhammad

Biochemistry Buzz ~12 Volume 14, May 2012

Staff Welfare Lunch at Aqua Marine @ Marina Mandarin

on 20 February 2012

Once again, Biochemistry staff bonded over good food and company at Aqua Marine@ Marina Mandarin on 20 February 2012. Congratulations to the lucky draw winners!

Page 13: New HOD’s message - bch.nus.edu.sg · Ms Nurfadillah Bte Mahmood Management Assistant Officer – Education Supervisor: Ms Aniza A. Wahid Assumed Duty: 26 March 2012 Mr Muhammad

Honours Open House on 27 February 2012 The open house was organized by our Honours Coordinator – Dr Deng Lih Wen to publicize the Honours projects availa-ble from the Department. This is also our opportunity to introduce students to our research work for future postgradu-ate education.

Biochemistry Buzz ~13~ Volume 14, May 2012

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The event was organised by Dr Thilo Hagen. It was a day of fun where various labs compete against each other in various interesting games at NUS stadium.

Sports & Fun Day on 11 May 2012

Biochemistry Buzz ~14~ Volume 14, May 2012

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Safety & Health Improvement Programme 2011/2012

on 29 February 2012 Department of Biochemistry Safety Committee won the Silver award for their project of The ChemSafe Transporter. The team consisted of A/P Caroline Lee, Dr Takao Inoue, Dr Lim Cheh Peng and Mr Wong Veen Senn.

Biochemistry Buzz ~15~ Volume 14, May 2012

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NUS Building Fire Safety Compliance Award 2011

on 20 March 2012

Biochemistry Buzz ~16~ Volume 14, May 2012

Page 17: New HOD’s message - bch.nus.edu.sg · Ms Nurfadillah Bte Mahmood Management Assistant Officer – Education Supervisor: Ms Aniza A. Wahid Assumed Duty: 26 March 2012 Mr Muhammad

Department of Biochemistry is 85 years old this year.

The oldest faculty in NUS is the Yong Loo Lin School of Medicine (107 years old), while the youngest is Saw Swee

Hock School of Public Health (SSHSPH) established in October 2011.

Before the modular system was introduced, examinations were not conducted at the end of each semester, but at the

end of the academic year for a year’s work!

Examinations were once held in exhibition halls such as those in the former World Trade Centre (now Harbour Front)

and IMM located at Jurong.

The minimum distance required between two tables in an examination hall is 0.7m.

On 19 July 1963, a fire broke out in the lecture theatres that were located directly above the Medical Library. Within

minutes, staff and students formed a human chain and books were passed from one person to another and rescued to

safety outside the building. Their quick response saved countless of library books!

If there is an emergency, you can contact the Campus Security 24/7 Hotline at 68741616 for Kent Ridge Campus.

Biochemistry Buzz ~17~ Volume 14, May 2012

Do You Know?

Page 18: New HOD’s message - bch.nus.edu.sg · Ms Nurfadillah Bte Mahmood Management Assistant Officer – Education Supervisor: Ms Aniza A. Wahid Assumed Duty: 26 March 2012 Mr Muhammad

Ms Shen Yanqing (Lab Executive, Supervisor: Dr Takao Inoue)

Congratulations to Yanging for her second child, a baby boy.

Baby News

Editorial Team

Biochemistry

Advisor: Prof Thiery Editor: Ms Aniza A Wahid Writers: Ms Dee Pham & Miss Fatin Umairah If we missed any news, please email to the editors at: [email protected]

Dr Wang Xueying

Congratulations to Dr Wang on her third child, a baby boy, Jonathan Teo.

Ms Chai Siaw Ching (Research Associate, Supervisor: Professor Jeyaseelan, Kandiah)

Congratulations to Siaw Ching for her second child, a baby girl, Putri Adrianna Chai Abdul Rasied.

Bon Voyage We bid adieu and wish them all the best for their future endeavors to:

Biochemistry Buzz ~18~ Volume 14, May 2012

Mr Zhang Kai Ms Lim Cheh Peng

Ms Dashayini Mahalingam Ms Lissya Lettisya Santaso

Mr Ye Mon Than Ms Ng Ah Sock Angie

Ms Kwok Wing Sze Alice Ms Lo Shu Mei Michelle

Mr Loo Eng Kiat Alvin Ms Chong Poh Kuan Shirly

Mr Wang Fan Ms Goh Kah Yee

Ms Lynette Lim Ms Lam Buu Duyen, Jenny