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SCIENTIFIC POSTER MEDALFirst Prize: Karen To, PGY5 Nephrology

Oral Cholecalciferol (Vitamin D3) Therapy in Prevalent Hemodialysis Patients: A Randomized Placebo Controlled Pilot Study

Supervisor: Drs. Catherine Clase, Azim Gangji

Second Prize: Andrea Lee, PGY5 Hematology

Incidence and Prevalence of Sickle Cell Disease in Ontario

Supervisor: Drs. John Waye, Andrew McFarlane

Dr. Shariq Haider, Research Director and Dr. Karen To, Scientific Poster First Prize

CLINICAL POSTER MEDALFirst Prize: Ian Mazzetti, PGY2 Medicine, Craig Ainsworth, PGY6 Cardiology

The Ace of Spades: Reverse Takotsubo Cardiomyopathy in the Context of Angiographic Embolization of Recurrent Metastatic Neuroendocrine Tumour of the Pancreas

Supervisor: Dr. Catherine Demers

Second Prize: Ronen Behar, PGY4 Gastroenterology

Mantle Cell Lymphoma in an Asymptomatic Patient with Multiple Lymphomatosis Polyposis: A Case Report and Literature Review

Supervisor: Dr. Frances Tse

Special thanks to Ms. Gail Trevisani who has been a strong advocate for Research Day over the years and has provided outstanding leadership in development of the event. In her retirement, Gail has left a remarkable legacy that will be a strength of the program for years to come.

RESIDENCY PROGRAM AWARDSJeff Ginsberg Subspecialty Resident Award, demonstrating excellence in professionalism, leadership and education. This award has been made possible by a donation from a patient of Dr. Jeff Ginsberg. Candidates are recognized for consistently displaying outstanding performance in clinical rotations, excellence in teaching, research and professionalism and commitment to academic achievement.

Recipients: Kylie Lepic and Christine Ribic

CMR Award for Excellence in Clinical Competence and Teaching. Nominees display a strong presence on the CTU and demonstrate excellence in education, administration and pro-fessional responsibility, serving as a role model for junior trainees.

Recipients: Douglas Wright, Zain Kassam, Thomas Haffner

Dr. Hui Lee Award for Excellence in Clinical Care and Teaching (PGY2). Nominees consistently exhibit excellence in clinical performance, strong education involvement with the undergraduate program and exemplary professionalism.

Recipients: Michelle Haroun, Andrew Burke, Simon Oczkowski

External Recognition Awards:Hamilton Health Sciences MSA Senior Resident Award: Thomas Haffner

Hamilton Health Sciences MSA Junior Resident Award: Ian Mazzetti, Andrew Burke

David Feldman Internal Medicine Award: Douglas Wright

Outstanding Resident Teaching Award, Medical Student Class of 2011: Zain Kassam

22nd Annual Resident Research Day in Medicine

Resident research was highlighted and celebrated at the Internal Medicine Research Day on May 25, 2011. This annual event allows residents, both core and subspecialty, to showcase their research and be recognized for excellence in clinical and scientific projects.

Ninety-one abstracts were submitted, and under the review of Dr. Shariq Haider, research direc-tor, and Drs. Catherine Demers, Frances Tse and John You, 27 projects were selected for clinical poster presentations, 17 for scientific poster pre-sentations and ten projects were selected for oral presentations. Judging was conducted by Drs. Will Harper, Marianne Talman and Irwin Walker (Clinical) and Drs. Hertzel Gerstein, Mark Loeb and Shannon Bates (Scientific).

2011 RESIDENT RESEARCH GRANT RECIPIENTSDr. Bram Rochwerg, PGY2 Medicine and Dr. Jason Cheung, PGY1 Medicine $5000BIOVISON : Does BIO-Impedance Analysis Predict Volume Overload States and Clinically Relevant Outcomes in Septic ICU Patients?Supervisor: Dr. Azim Gangji

ORAL PRESENTATIONSGold Medal: Saeed Darvish-Kazem, PGY1 Medicine

The Impact of Perioperative Clonidine on Cardiovascular Events in Patients Undergoing Noncardiac Surgery: A Systematic Review and Meta-analysis

Supervisor: Dr. PJ Devereaux

Silver Medal: Bram Rochwerg, PGY2 Medicine and Jason Cheung, PGY1 Medicine

BIOVISON : Does BIO-Impedance Analysis Predict Volume Overload States and Clinically Relevant Outcomes in Septic ICU Patients?

Supervisor: Dr. Azim Gangji

Bronze Medal: Lacey Pitre, PGY1 Medicine

ITERs, OSCEs, MCQs and SAQs: How Well Do Commonly Used Resident Evaluation Formats Correlate With Each Other?

Supervisor: Drs. Parveen Wasi, Kelly Dore

Dr. Christine Ribic and Dr. Kylie Lepic, 2011 Jeff Ginsberg Subspecialty Award recipients, with Dr. Parveen Wasi (centre), Program Director

110

Professor and Chair O’Byrne, Paul M. Respirology

Professor Emeritus Banerjee, Sikhar Physical Medicine and Rehabilitation Bayne, Ronald J. Geriatric MedicineBrain, Michael Hematology and Thromboembolism Churchill, David N. Nephrology Clark, David A. Clinical Immunology and Allergy Daniel, Edwin E. Neurology Dwyer, Daniel E. General Internal Medicine Fallen, Ernest L. Cardiology Heigenhauser, George J.F. Respirology Hirsh, Jack Hematology and ThromboembolismJones, Norman L. Respirology Kwan, David C.Y. Cardiology Laidlaw, John C. General Internal MedicineLudwin, David Nephrology Mandell, Lionel A. Infectious Diseases McComas, Alan J. Neurology Mishkel, Maurice General Internal MedicineMolloy, William (Willie) D. Geriatric Medicine Morse, John L.C. Respirology Muir, David C.F. Respirology Neufeld, Victor R. General Internal MedicinePowles, Peter A.C. Critical Care/Respirology Rangachari, P.K. Gastroenterology Robinson, John G. Cardiology Rodger, Ian Respirology Rosenthal, Donald Dermatology Smith, E.K.M. (Kinsey) Nephrology Sweeney, George D. Gastroenterology/ Clinical Pharmacology and TherapeuticsTanser, Paul H. Cardiology Tsega, Edemariam General Internal Medicine Turpie, Alexander (Graham) G. General Internal Medicine /Hematology and ThromboembolismTurpie, Irene D. Geriatric Medicine Upton, Adrian R.M. Neurology Walsh, William J. General Internal Medicine Werstiuk, Eva Hematology and Thromboembolism

Endowed Chairs and ProfessorshipsAdachi, Rick Alliance For Better Bone Health Chair In RheumatologyAnand, Sonia Eli Lilly Canada/May Cohen Chair In Women’s HealthAnand, Sonia Heart And Stroke Foundation of Ontario/Michael G. DeGroote Chair In Population Health ResearchAustin, Richard Amgen Canada Chair In NephrologyBaker, Steven Hamilton Hospitals Assessment Centre Endowed Professorship In Neuromuscular DiseaseCividino, Alfred Abbott Chair in Education in RheumatologyCollins, Stephen GlaxoSmithKline Chair In GastroenterologyConnolly, Stuart Salim Yusuf Chair In CardiologyCook, Deborah McMaster University/St. Joseph’s Healthcare Regional Academic Chair in Critical Care MedicineCrowther, Mark Leo Pharma Chair in Thromboembolism ResearchDenburg, Judah William J. Walsh Professorship In MedicineGerstein,Hertzel Population Health Institute Chair In Diabetes Research And CareGinsberg, Jeffrey David Braley and Nancy Gordon Chair In Thromboembolic DiseaseLarche, Mark McMaster University/GlaxoSmithKline Chair in Lung Immunology at St.Joseph’s HealthcareLoeb, Mark Michael G. DeGroote Chair in Infectious DiseasesMoayyedi, Paul Richard Hunt/AstraZeneca Chair In GastroenterologyO’Byrne, Paul Moran Campbell Chair In Respiratory MedicinePanju, Akbar Medard DeGroote Chair In MedicinePapaioannou, Alexandra Eli Lilly Canada Chair In OsteoporosisSahlas, Demetrios Michael G. DeGroote Professorship In Stroke ManagementSears, Malcolm AstraZeneca Chair In Respiratory EpidemiologyTurnbull, John Andrew Bruce Douglas Chair In NeurologyWallace, John Farncombe Family Chair In Digestive Health ResearchWeitz, Jeffrey Heart And Stroke Foundation Of Ontario/J. Fraser Mustard Chair In Cardiovascular ResearchYusuf, Salim Heart And Stroke Foundation Of Ontario/Marion W. Burke Chair In Cardiovascular Disease

Faculty

Dr. Chris Hillis, left, and Dr. Han-Oh Chung, right, present the Outstanding Specialty Rotation award to Geriatrics

Dr. Saeed Darvish-Kazem, Gold Medal, Oral Presentation with Dr. Shariq Haider, Research Director

Resident Awards to Faculty:Faculty Internist and Faculty Subspecialty Award for excellence in clinical teaching, selected by residents.

General Internal Medicine recipient: Zara Khalid

Subspecialty recipient: Tim Karachi

Subspecialty Rotation Award is presented annual-ly to the rotation that consistently delivers exem-plary educational experience to the residents.

Recipient: Geriatrics

Resident Program ContributionA remarkable strength of the McMaster Internal Medicine Residency Program continues to be the involvement and leadership of the residents. Their innovative contributions deserve recogni-tion and commendation.

Education Committee: Zain Kassam, Han-Oh Chung, Andrew Burke, Chris Hillis, Lacey Pitre, Josh Manolakos

Academic Half Day committee co-chairs: Melissa Chan, Natasha Bollegala

TREaT Curriculum: Zain Kassam, Andrew Burke, Ian Mazzetti, Raj Hundal, Simon Oczkowski, Faizan Amin, Lacey Pitre

Managerial Curriculum: Andrew Burke, Chris Hillis

Journal Club: Abbas Merali, Bram Rochwerg, Deborah Siegal

Simulation Committee: Andrew Gibson, Tom Haffner, Bram Rochwerg, Doug Wright, Nooreen Popat, Raj Hundal, Callum Dargavel, Faizan Amin, Mohan Cooray, Joshua Manolakos, Nauzer Forbes

Procedure Handbook: Nooreen Popat

Jan Taylor Administrator Internal Medicine Residency Program

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112

FACULTY

Haider, Shariq General Internal Medicine/ Infectious DiseasesHanmiah, Rajendar General Internal MedicineHarper, William General Internal Medicine/ Endocrinology and MetabolismHarvey, David T. Physical Medicine and RehabilitationHealey, Jeff Cardiology Hunt, Dereck General Internal Medicine/ Endocrinology and MetabolismJones, Graham L. Critical Care Kamath, Mark Cardiology/NeurologyKarachi, Tim Critical Care/General Internal Medicine/ RespirologyKeith, Paul K. Clinical Immunology and AllergyKhalidi, Nader Rheumatology Kolb, Martin Respirology Kraus, Peter Critical Care Krepinsky, Joan Nephrology Liaw, Patricia Hematology and ThromboembolismLima, Hermenio Dermatology Linkins, Lori-Ann Hematology and ThromboembolismMargetts, Peter Nephrology Marr, Sharon Geriatric Medicine/ General Internal MedicineMarshall, John GastroenterologyMcMullin, Joseph General Internal Medicine Mehta, Shamir Cardiology Misiaszek, Brian Geriatric MedicineMontgomery, Alison Cardiology Morgan, David G. GastroenterologyMukherji, Atreyi Infectious Diseases/ General Internal MedicineMuniz, Flor Physical Medicine and RehabilitationNair, Girish Cardiology Nair, Parameswaran Respirology Natarajan, Madhu K. Cardiology Prebtani, Ally Endocrinology and Metabolism/General Internal MedicineRabbat, Chris Nephrology Ribas, C. Sebastian Cardiology Rokoss, Mike Cardiology Russell, David J. Nephrology Sahlas, Demetrios (Jim) Neurology Salehian, Omid Cardiology Salena, Bruno J. GastroenterologySehmi, Roma Respirology Spyropoulos, Alex Hematology and Thromboembolism

Stanton, Eric B. Cardiology Steinberg, Gregory Endocrinology and Metabolism Talman, Marianne General Internal Medicine Tang, Damu Nephrology Tomlinson, Charles W. Cardiology Treleaven, Darin Nephrology Tse, Frances GastroenterologyValettas, Nicholas Cardiology Velianou, James L. Cardiology Welsford, Michelle Emergency MedicineWerstuck, Geoff Hematology and ThromboembolismWoo, Tricia Geriatric MedicineWorster, Andrew Emergency MedicineYegappan, Chidambaram Neurology

Assistant Professor Amer, Rebecca General Internal Medicine/RespirologyArnold, Donald M. (Donnie) Hematology and ThromboembolismAsk, Kjetil Respirology Azzam, Khalid General Internal Medicine Bader, Mazen Infectious DiseasesBaker, Steven Physical Medicine and RehabilitationBeattie, Karen Rheumatology Bercik, Premysl GastroenterologyBobba, Raja Rheumatology Braga, Manoela Endocrinology and Metabolism Carmona, Rajendra Rheumatology Chakroborty, Amitabha General Internal Medicine/ Infectious DiseasesChan, Howard Hematology and ThromboembolismDivakaramenon (Menon), Syamkumar (Syam) Cardiology Dore, Kelly Drost, Nicole Respirology Duong, MyLinh General Internal Medicine/ RespirologyForsythe, Paul Respirology Ganame, Javier Cardiology Gangji, Azim Nephrology Greenwald, Eric GastroenterologyHalder, Smita GastroenterologyJohnstone, Jennie Infectious DiseasesJolly, Sanjit Cardiology Joseph, Geena General Internal Medicine / NephrologyKhan, Khurram GastroenterologyLabiris, N. Renée Respirology Larché, Margaret Rheumatology/ Clinical Immunology and AllergyLegassie, Jenny General Internal Medicine Leontiadis, Grigorios Gastroenterology

Geographic Full-Time

Professor Adachi, Jonathan (Rick) Rheumatology Anand, Sonia Cardiology / Thromboembolism/ General Internal MedicineAustin, Richard (Rick) Nephrology Buller, Christopher Cardiology Collins, Stephen M. GastroenterologyConnolly, Stuart J. Cardiology Cook, Deborah J. Critical Care/General Internal MedicineCox, Gerry Respirology Crowther, Mark A. Hematology and ThromboembolismDenburg, Judah A. Clinical Immunology and AllergyDouketis, James D. General Internal Medicine/ Hematology and ThromboembolismFuller, Hugh D. General Internal MedicineGagnon, Micheline D.M. Geriatric MedicineGerstein, Hertzel C. Endocrinology and MetabolismGinsberg, Jeffrey Hematology and ThromboembolismGrover, Ashok K. GastroenterologyHart, Lawrence E. Rheumatology Heddle, Ms. Nancy Hematology and ThromboembolismHolbrook, Anne General Internal Medicine/Clinical Pharmacology and TherapeuticsHolder, Douglas A. CardiologyHuizinga, Jan GastroenterologyHunt, Richard H. GastroenterologyIngram, Alistair J. Nephrology Inman, Mark Respirology Jaeschke, Roman Z. Critical Care/NeurologyJanssen, Luke J. RespirologyKearon, Clive M. Respirology/Hematology and ThromboembolismKelton, John G. Hematology and ThromboembolismKillian, Kieran J. RespirologyLarché, Mark Clinical Immunology and Allergy/RespirologyLeber, Brian F. Hematology and ThromboembolismLonn, Eva M. Cardiology Lumb, Barry J. GastroenterologyMazurek, Michael F. Neurology McIvor, R. Andrew Respirology McKelvie, Robert S. Cardiology Meade, Maureen Critical Care Moayyedi, Paul GastroenterologyMorillo, Carlos Cardiology

Morillo, Luis Neurology Nesathurai, Shanker Physical Medicine and RehabilitationPanju, Akbar A. General Internal MedicinePapaioannou, Alexandra Geriatric Medicine/ RheumatologyPatel, Ameen General Internal MedicinePatterson, Christopher J. Geriatric MedicineRathbone, Michel P. NeurologySchulman, Sam Hematology and ThromboembolismSears, Malcolm R. RespirologySpencer, Frederick Cardiology/Hematology and ThromboembolismSurette, Michael GastroenterologyTeo, Koon Cardiology Turnbull, John D. Neurology Walker, Irwin R. Hematology and ThromboembolismWallace, John GastroenterologyWaserman, Susan Clinical Immunology and AllergyWasi, Parveen Hematology and ThromboembolismWeitz, Jeffrey I. Hematology and Thromboembolism Yusuf, Salim Cardiology

Associate Professor Ackerman, Margaret J. Emergency MedicineAllen, Christopher J. Respirology Arlen, Dianne J. Nephrology Armstrong, David GastroenterologyBates, Shannon Hematology and ThromboembolismBrimble, Scott Nephrology Carlisle, Euan J.F. Nephrology Chan, Wee Shian General Internal MedicineClase, Catherine Nephrology Cowan, David Geriatrics Cunnington, John P.W. General Internal Medicine Demers, Catherine Cardiology Dokainish, Hisham Cardiology Dorasamy, Punginathn General Internal Medicine/ RespirologyEikelboom, John Hematology and ThromboembolismEl-Helou, Philippe Infectious DiseasesFox-Robichaud, Alison Critical CareFreitag, Andreas P. (Andy) Respirology/Critical CareFulford, Martha Infectious DiseasesGanguli, Subhas GastroenterologyGauvreau, Gail Respirology Gilani, Ammar Neurology Gordon, Elaine P. Cardiology Gross, Peter Hematology and Thromboembolism

114

FACULTY

Newhouse, Michael Respirology Rosenbloom, David Neurology Rotstein, Coleman M.F. Infectious Diseases

Associate Clinical Professor Achong, Michael R. General Internal Medicine/ Infectious DiseasesAnderson, Julia Hematology and ThromboembolismArck, Petra Clinical Immunology(returned to Germany) and Allergy Bianchi, Fernando A. Rheumatology Bradley, Christine A. Respirology/Critical CareBraun, Anne E. Geriatric MedicineChiba, Naoki GastroenterologyCurnew, Gregory P. Cardiology/ General Internal MedicineDarracott, John Physical Medicine and Rehabilitation Davis, Clive Respirology Ddungu, Henry Hematology Derby, Ian R.G. Neurology Dolovich, Myrna Respirology Faraawi, Rafat Rheumatology Giammarco, Rosella Neurology Gibson, James C. General Internal Medicine/ Critical CareGoodwin, Susan E.B. Neurology Greenway, Keith Emergency MedicineHamielec, Cindy M. Respirology/Critical CareIacobellis, Gianluca Endocrinology and Metabolism Jichici, Draga Critical Care Kagoma, Peter K. Hematology and ThromboembolismKerigan, Anthony T. Respirology/Geriatric Medicine Kumbhare, Dinesh A. Physical Medicine and Rehabilitation/ Rheumatology Lester, Frances T. General Internal Medicine McLellan, Allan P. Respirology/Critical CareMizera, Ryszard General Internal Medicine Mulji, Amin S. Cardiology O’Donnell, Martin General Internal Medicine/ Hematology and Thromboembolism/ Geriatric MedicineOczkowski, Wieslaw J. Neurology Paulseth, John E. Neurology Pengelly, Lionel (David) Respirology Perez, Gavino R.D. General Internal Medicine Prasad, Sadhana Geriatric MedicinePryszlak, Michael Cardiology/Nuclear Medicine Pugsley, Stewart O. Respirology Puksa, Serge Respirology/Critical CareRamsdale, Helen E. Respirology

Rossman, Richard L. GastroenterologySalama, Suzette General Internal Medicine Sealey, Brian Cardiology Seaton, Trevor L. GastroenterologySebaldt, Rolf J. Rheumatology/Clinical Pharmacology and Therapeutics Sternbach, Marion Hematology and ThromboembolismTrotter, Judy E. Physical Medicine and Rehabilitation Vender, Ronald D. Dermatology Whitehead, Lori N. Respirology Wismer, Judy Dermatology

Assistant Clinical Professor Abid, Simona Geriatric MedicineAboo, Ismail Y. Alexander, Michael General Internal Medicine/ Clinical Immunology and AllergyBabapulle, Mohan Cardiology Bellissimo, Agostino Emergency MedicineBenaroia, Mark Nephrology Bentley, Todd Physical Medicine and Rehabilitation Berlingieri, Joseph General Internal Medicine Bertley, John Respirology Biman, Birubi Respirology Booth, John D. Endocrinology and Metabolism/ General Internal MedicineBoulos, Pauline Rheumatology Cavalcanti, Rodrigo General Internal Medicine Chan, Terence General Internal Medicine Channan, Peter Emergency MedicineChari, Vinjamuri Physical Medicine and Rehabilitation Cherian, Joe Emergency MedicineChernish, Robert General Internal Medicine Chew, Donald Neurology Chmiel, Agnes Physical Medicine and Rehabilitation Chow, Andrew Rheumatology Chow, Clara Cardiology Connolly, Michael Dermatology Crossley, John Emergency MedicineCrowe, Adrian Emergency MedicineCyr, Michael Clinical Immunology and Allergy De Rubeis, Debra Neurology Delrue, Andrea General Internal Medicine Didyk, Nicole Geriatric MedicineEby, Robbie-Jane Emergency MedicineEdstrom, Karen Dermatology Fan, Jerome Emergency Medicine

Lim, Wendy Hematology and ThromboembolismLuthra, Meera Endocrinology and Metabolism/General Internal MedicineMagloire, Patrick M. Cardiology Mallin, A. Rebecca Emergency MedicineMatsos, Mark Rheumatology Mazzadi, Sergio General Internal Medicine/ GastroenterologyMcLeod, Heather Geriatric MedicineMertz, Dominik Infectious DiseasesMohammed, Naufal Neurology/General Internal MedicineNeary, John General Internal Medicine Neighbour, Helen Clinical Immunology and Allergy/RespirologyO’Leary, Ms. Deniece General Internal Medicine O’Shea, Timothy Infectious Diseases/ General Internal MedicinePerri, Dan Clinical Pharmacology and TherapeuticsPuglia, Marco (Mark) GastroenterologyPunthakee, Zubin Endocrinology and Metabolism Rashid, Shirya Hematology and ThromboembolismRudkowski, Jill General Internal Medicine Schwalm, Jon-David (JD) Cardiology Shapiro, Michelle Neurology Sherbino, Jonathan Emergency MedicineSheth, Tej Cardiology Singhal, Nishma Infectious DiseasesSoth, Mark Respirology/Critical CareSpaziani, Robert GastroenterologySt. Onge, Joye Geriatric MedicineTiboni, Maria General Internal Medicine Todd, David Respirology Tsoi, Keith GastroenterologyTunks, Marcel Respirology Valani, Rahim Emergency MedicineVerdú, Elena GastroenterologyVerhovsek, Madeleine Hematology and ThromboembolismWebert, Kathryn Hematology and ThromboembolismWhittingham, Heather Critical Care Witt-Sullivan, Helga B. GastroenterologyWoodward, Kevin Infectious DiseasesYang, Robert Nephrology You, John General Internal Medicine

Joint/Associate Members Allaby, Cheryl Geriatric MedicineBeyene, Joseph General Internal Medicine

Bienenstock, John Clinical Immunology and AllergyBrozek, Jan Clinical Immunology and AllergyConnolly, John Physical Medicine and Rehabilitation Devereaux, Philip J. General Internal Medicine/CardiologyDon-Wauchope, Andrew Endocrinology and Metabolism Guyatt, Gordon H. General Internal Medicine/ RespirologyHaynes, R. Brian General Internal MedicineHayward, Catherine P.M. Hematology and ThromboembolismIorio, Alfonso Hematology and ThromboembolismJager, Pieter L. General Internal Medicine Lee, Christine Infectious DiseasesLevine, Mitch A.H. Clinical Pharmacology and Therapeutics/ General Internal MedicineLoeb, Mark Infectious DiseasesMain, Cheryl L. Infectious DiseasesNeville, Alan J. General Internal MedicinePowers, Peter J. Hematology and ThromboembolismSagar, Stephen M. General Internal Medicine Schunemann, Holger General Internal Medicine Singnurkar, Amit Cardiology Smieja, Marek Infectious DiseasesSur, Ranjan General Internal Medicine Tarnopolsky, Mark A. Physical Medicine and Rehabilitation Waye, John Hematology and ThromboembolismWong, Raimond General Internal Medicine Wong-Pack, William Cardiology

Part-time

Clinical Professor Bensen, William G. Rheumatology Bolli, Peter Nephrology/CardiologyBrown, William (Bill) Neurology Ducharme, James Emergency MedicineFernandez, Peter Cardiology Higgins, David A. Respirology Kean, Walter F. Rheumatology Khan, Aliya A. Geriatric Medicine/ Endocrinology and Metabolism Langella, Philippe GastroenterologyMacpherson, Andrew Gastroenterology

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FACULTY

Safranyos, Richard Geriatric MedicineSarkaria, Gagandeep Geriatric MedicineSavelli, Gordina E. Neurology Saveriano, Nellina Dermatology Saxena, Shiv General Internal Medicine Schwarz, Dan Cardiology Scocchia, Tulio Rheumatology Sellens, Catherine Emergency MedicineShaikh, Saeed Rheumatology Sharad, Sunil General Internal Medicine Sharieff, Saleem General Internal Medicine Sharma, Sangita Emergency MedicineShetty, Panduranga (Pandu) General Internal Medicine Silva, Jaime Neurology Sirek, Ann Endocrinology and Metabolism Sivji, Yasmin General Internal Medicine Sloka, J Scott Neurology Smith, Kevin (Dr.) President and CEO, SJHSmith, Mr. Jim Hematology and ThromboembolismSmith, Ruth Physical Medicine and Rehabilitation Stallwood, George R. Cardiology/Critical CareStewart, Alan Russell General Internal Medicine Sullivan, Brian J. Cardiology Sullivan, Hugh P. Cardiology Tihal, Hirawan Cardiology Tougas, Manon General Internal Medicine Turineck, David Emergency MedicineUpadhye, Suneel Emergency Medicine/ Physical Medicine and Rehabilitation Varey, Peter Physical Medicine and Rehabilitation Velasquez, Juan M. General Internal Medicine Vignjevic, Peter Dermatology Visram, Farzin Critical Care/General Internal Medicine/ Respirology Vitou, Louise Nephrology White, Fred Clinical Immunology and Allergy Whittaker, Susan Hematology and ThromboembolismYakemchuk, Valerie N. Nuclear MedicineYang, John Geriatric MedicineZawadowski, Andrew Cardiology Zimakas, George General Internal Medicine Lecturer McFarlane, Mr. Andrew Hematology and Thromboembolism

Moffat, Karen Hematology and Thromboembolism

Scholars and Fellows

Clinical Scholars Khalid, Zahira (Zara) General Internal Medicine Kraeker, Christian General Internal Medicine Pai, Menaka Hematology and ThromboembolismPicard, Pierre Neurology Van Spall, Harriette Cardiology Walsh, Mike Nephrology Xenodemetropoulos, Ted GastroenterologyYakubovich, Natalia Endocrinology and Metabolism

Clinical Fellows Al Ghunaim, Shothour Physical Medicine and Rehabilitation Al Qarni, Fatimah Abdullah Neurology Al Rahimi, Jamilah Saad M. Cardiology/Internal Medicine Al Shahrani, Mohammed Saeed S. Critical Care MedicineAlanazi, Safug H.A. Critical Care MedicineAl-Ebrahim, Fahad A.M.A. Gastroenterology/ Internal MedicineAl-Enezi, Farhan Zayed Respiratory Medicine/Munzil Ahus Internal MedicineAl-Hanoot, Ibraheem Khalifa Gastroenterology/Salman Internal MedicineAl-Harbi, Abdulrahman Cardiology/Internal MedicineAlQubbany, Atif Wageh Cardiology/Internal Medicine Alsayb, Majd Abdulaziz Gastroenterology/ Internal MedicineAl-Sayegh, Mohammad A. Allergy/ Clinical Immunology/Internal Medicine Alshehri, Abdulrahman Ali Hematology/Internal Medicine Bokhamsen, Ali Ibrahim Hematology/Internal Medicine Braga, Manoela Figueiredo Endocrinology/Internal MedicineCarter, Flloyd Patrick Gastroenterology/Internal Medicine Castilloux, Jean-Francois Hematology/Internal Medicine Chemello, Diego Cardiology/Internal MedicineChin, Ashley Cardiology/Internal MedicineDarwish Hassan, Ahmed Allergy/ ClinicalAbd El Magid Immunology/Internal MedicineDutta, Usha Gastroenterology/ Internal MedicineEl Bayomy, Mohamed Cardiology/Internal

Farrauto, Leo Physical Medicine and Rehabilitation Fergani, Houssein GastroenterologyFerreira, Ivone Respirology Fowlis, Ronald Cardiology Frank, Peter Emergency MedicineGarnis-Jones, Sylvia Dermatology Ghouse, Ali T. Physical Medicine and Rehabilitation Gill, Gurpreet Goode, J. Eric General Internal Medicine/ CardiologyGottschalk, Raymond Respirology Grad, Sharon Physical Medicine and Rehabilitation Greenbaum, Joseph Clinical Immunology and Allergy Grenier, Catherine Emergency MedicineGupta, Milan Cardiology Gwardjan, Andrew Physical Medicine and Rehabilitation Ha, Michael Emergency Medicine Haaland, Derek Rheumatology/Clinical Immunology and AllergyHall, Susan E.H. Dermatology Hanna, Brian D. Rheumatology Hastings, Deborah M. Cardiology Hawley, Kristopher Emergency MedicineHealey, Andrew Emergency MedicineHeckman, George Geriatric MedicineHentschel, Eric Respirology Hersi, Ali Emergency MedicineHess, Allan Cardiology Ho, Victoria Respirology Hosek, Paul Husein, Nadira Endocrinology and Metabolism Ibrahim, Khaled GastroenterologyIoannidis, George Rheumatology Jackson, Mary Respirology/General Internal MedicineJohnston, Mr. Neil Respirology Jolly, Shivinder Nephrology Joshi, Atul General Internal Medicine Kaminska, Elzbieta A. Rheumatology Karimi, Khalil Clinical Immunology and Allergy Keen, Sabina Geriatric MedicineKhan, Omar Physical Medicine and Rehabilitation Khandelwal, Mukesh Nephrology Kim, Harold Clinical Immunology and Allergy Kim, Simon General Internal Medicine Kitching, Allan D. Cardiology Kohli, Sandeep (Sonny) Singh General Internal Medicine Koubaesh, Yousery General Internal Medicine Kronby, Michael H. Neurology

Lagrotteria, Danny Nephrology Lai, Christopher Cardiology Lam, Leo Nephrology Langridge, Jonathon Respirology Lebert, Phyllis A. General Internal Medicine/Clinical Immunology and AllergyLetcher, Kevin Physical Medicine and Rehabilitation Lewis, David Geriatric MedicineLiu, Tom Nephrology Lo, Raymond Neurology Lozinski, Ala Z. Dermatology MacFadyen, John General Internal Medicine Malcolm, W. Neil Critical Care Mandalfino, Patricia Neurology Marriott, Christopher General Internal Medicine Massarella, Carys Emergency MedicineMathoo, Julian Physical Medicine and Rehabilitation/ Rheumatology McClennan, Sarah Emergency MedicineMcCoy, Kathy GastroenterologyMcMillan, Richard Physical Medicine and Rehabilitation Messieh, Mary Clinical Immunology and Allergy Meyerson, Jeffrey Endocrinology and Metabolism Miller, Paul Emergency MedicineMody, Anita Cardiology Moore, Ms. Jane Hematology and ThromboembolismMorris, Catherine A.W. General Internal Medicine Muhn, Channy Dermatology Nagai, Ryuta Nephrology O’Malley, Maureen Dermatology Pallie, Sven Cardiology Pandey, Amritanshu Shekhar Cardiology Pardhan, Alim Emergency MedicineParlea, Luciana Endocrinology and Metabolism Pasricha, Ajai General Internal Medicine Pavlova, Viktoria Rheumatology Peat, Mary I. Geriatric MedicinePetrik, Shawn Hematology and ThromboembolismPlaxton, William R. Preyra, Ian Emergency MedicinePuvendran, Samuel Quinn, Mr. Michael Raco, Dominic Cardiology Rempel, Brenda Endocrinology and Metabolism Richards, Douglas Emergency MedicineRosen, Nathan Dermatology Ryan, Thomas J. General Internal Medicine/ Endocrinology and Metabolism

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FACULTY

New Faculty AppointmentsFull-time Dr. Margaret Ackerman Emergency Medicine Dr. Rebecca Amer General Internal Medicine/RespirologyDr. Kjetil Ask RespirologyDr. Manoela Braga EndocrinologyDr. Wee-Shian Chan General Internal MedicineDr. Kelly Dore General Internal MedicineDr. Martha Fulford Infectious DiseasesDr. Smita Halder GastroenterologyDr. Rebecca Mallin Emergency MedicineDr. Heather McLeod GeriatricsDr. Dominik Mertz Infectious DiseasesDr. John Neary General Internal MedicineDr. Tim O’Shea General Internal Medicine/Infectious DiseasesDr. Menaka Pai HematologyDr. Marco Puglia GastroenterologyDr. Jon-David Schwalm CardiologyDr. Michelle Shapiro NeurologyDr. Marcel Tunks RespirologyDr. Rahim Valani Emergency Medicine

Part-time Dr. Ismail Aboo Dr. Joseph Berlingieri General Internal MedicineDr. Peter Channan Emergency MedicineDr. Gurpreet Gill Dr. Catherine Grenier Emergency MedicineDr. Derek Haaland Clinical Immunology and AllergyDr. Andrew Healey Emergency MedicineDr. Paul Hosek Dr. George Ioannidis RheumatologyDr. Sonny Kohli General Internal MedicineDr. Jonathan Langridge RespirologyDr. Frances Lester General Internal MedicineDr. Anita Mody CardiologyDr. Amritanshu Pandey CardiologyDr. Luciana Parlea EndocrinologyDr. Viktoria Pavlova RheumatologyDr. Shawn Petrik Hematology and ThrombosisDr. William Plaxton Dr. Samuel Puvendran Dr. Sangita Sharma Emergency MedicineDr. J. Scott Sloka NeurologyDr. Juan Velasquez General Internal Medicine

Management Staff Annette Rosati Director of AdministrationTerry De Cola Office ManagerCathy Stampfli Tenure and Promotion Coordinator/Faculty Recruitment CoordinatorSara Sellers Special Projects CoordinatorLisa Greer Finance ManagerTammy Lintack Finance CoordinatorJakki Taylor Site Finance Coordinator, MUMC/TaARIHelen Murray Site Finance Coordinator, HGH/JHCC/SJH/SPHGraeme Matheson AFP AnalystLynda Peters Payroll CoordinatorLorrie Reurink Human Resources ManagerZrinka DiVincenzo Human Resources CoordinatorCourtney Humes Operations Site Coordinator, MUMCSarah-Kai Antanaitis Operations Site Coordinator, SJHRoberta Petitti Operations Site Coordinator, HGHGail LaForme Operations Site Coordinator, HDGH/CHJan Taylor Administrator, Internal Medicine Residency Training Program

El Said Mohamed MedicineHwang, Hun-Gyu Hematology/Internal MedicineKim, Tae Hyong Infectious Diseases/ Internal MedicineLai, Tony Fang-Mo Cardiology/Internal MedicineLira Lea-Plaza, Gonzalo Rafael Cardiology/Internal MedicineMehta, Maria Zildany Pinheiro Cardiology/Internal MedicineMehta, Niraj Cardiology/Internal MedicineMuhindo, Rose Kabagambe Nephrology/Internal MedicinePai, Menaka CIP/HematologyPerera, Suresh Cardiology/Internal MedicineShatnawei, Abdullah Gastroenterology/InternalSuleiman Abdull MedicineSpringer-Cyrus, Erika Angela Gastroenterology/Internal MedicineTayeb, Sarah Abdulsalam Infectious Diseases/ Internal Medicine

Research Fellows Imaoka, Haruki Respiratory Medicine/ Internal MedicineKinoshita, Takashi Internal MedicineNerenberg, Kara Aleksandra Internal Medicine

Faculty Promotion

Full-time Professor Dr. Micheline Gagnon Ms. Nancy Heddle Dr. Mark Inman Dr. Maureen Meade

Associate Professor Dr. Carlos Ribas Dr. Omid Salehian Dr. Frances Tse Dr. Peter Gross

Part-timeAssociate Clinical ProfessorDr. Rafat FaraawiDr. Suneel Upadhye

Faculty ReappointmentsFull-timeDr. Donald ArnoldDr. Premysl BercikDr. MyLinh DuongDr. Azim Gangji

Dr. Sanjit JollyDr. Merra LuthraDr. Sharon MarrDr. Jill RudkowskiDr. Jonathan SherbinoDr. Robert SpazianiDr. Joye St. OngeDr. David ToddDr. John You

Part-timeDr. Michael AlexanderDr. John BertleyDr. John BoothDr. Christine BradleyDr. Vinjamuri ChariDr. Naoki ChibaDr. Michael CyrDr. James DucharmeDr. Karen EdstromDr. Ivone FerreiraDr. Peter FrankDr. Martha FulfordDr. Rose GiammarcoDr. Michael HaDr. Cindy HamielecDr. Harold KimDr. Dinesh KumbhareDr. Christopher LaiDr. Leo LamDr. Phyllis LebertDr. Raymond LoDr. Douglas MartinMr. Andrew MacFarlaneDr. Richard McMillanDr. Mary MessiehDr. Paul MillerDr. Karen MoffatMs. Jane MooreDr. Maureen O’MalleyDr. Sven PallieDr. John PaulsethDr. Sadhana PrasadDr. Ian PreyraDr. Michael PryszlakDr. Suzette SalamaDr. Tulio ScocchiaDr. Brian SealeyDr. Rolf SebaldtDr. Jagmeet SethiDr. Kevin SmithDr. Hugh SullivanDr. Brian Sullivan Dr. Judy TrotterDr. Ronald Vender Dr. Farzin Visram Dr. Fred White Dr. Susan Whittaker

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ADACHI, J.D.Sambrook P, Cranney A, Adachi JD. Intravenous ibandronate reduces the risk of non-vertebral fractures: post-hoc analysis from DIVA. Curr Med Res Opin. 2010;26:599-604.

Jamal SA, Swan VJ, Brown JP, Hanley DA, Prior JC, Papaioannou A, Langsetmo L, Josse RG, Canadian Multicentre Osteoporosis Study Research Group. Kidney function and rate of bone loss at the hip and spine: the Canadian Multicentre Osteoporosis Study. Am J Kidney Dis. 2010;55:291-9.

MacIntyre NJ, Stavness CL, Adachi JD. The Safe Functional Motion test is reliable for assessment of functional movements in individuals at risk for osteoporotic fracture. Clin Rheumatol. 2010;29:143-50.

Sawka AM, Ismaila N, Cranney A, Thabane L, Kastner M, Gafni A, Woodhouse LJ, Crilly R, Cheung AM, Adachi JD, Josse RG, Papaioannou A. A scoping review of strategies for the preven-tion of hip fracture in elderly nursing home residents. PLoS ONE. 2010;5(3):e9515.

Langsetmo L, Poliquin S, Hanley DA, Prior JC, Barr S, Anastassiades T, Towheed T, Goltzman D, Kreiger N, the CaMos Research Group. Dietary patterns in Canadian men and women ages 25 and older: relationship to demographics, body mass index, and bone mineral density. BMC Musculoskeletal Disorders. 2010;11:20.

Grima D, Papaioannou A, Airia P, Ioannidis G, Adachi JD. Adverse events, bone mineral density and discontinuation associated with generic alendronate among postmenopausal women previously tolerant of brand alendronate: a retrospective cohort study. BMC Musculoskeletal Disorders. 2010;11:68.

Jager PL, Slart RHJA, Webber CL, Adachi JD, Papaioannou AL, Gulenchyn KY. Combined vertebral fracture assessment and bone mineral density measurement: a patient-friendly new tool with an important impact on the Canadian risk fracture classification. CARJ. 2010;1:1-7.

Giangregorio L, Thabane L, Cranney A, Adili A, deBeer J, Dolovich L, Adachi JD, Papaioannou A. Osteoporosis knowledge among individuals with a recent fragility fracture. Orthop Nurs. 2010;29:99-107.

Christiansen C, Chesnut III CH, Adachi JD, Brown JP, Fernandes CE, Kung AWC, Palacios S, Levine AB, Chines AA, Constantine GD. Safety of bazedoxifene in a randomized, double-blind, placebo- and active-controlled phase 3 study of postmeno-pausal women with osteoporosis. BMC Musculoskelet Disord. 2010;11:130.

Zhou W, Langsetmo L, Berger C, Adachi JD, Papaioannou A, Ioannidis G, Webber C, Atkinson SA, Olszynski WP, Brown JP, Hanley DA, Josse R, Kreiger N, Prior J, Kaiser S, Kirkland S, Goltzman D, Davison KS, and the CaMos Research Group. Normative Bone Mineral Density Z-scores for Canadians aged 16-24 years: The Canadian Multicentre Osteoporosis Study. J Clin Densitometry. 2010;13:267-76.

Lau AN, Ioannidis G, Potts Y, Giangregorio LM, Van der Horst MLM, Adachi JD, Papaioannou A. What are the beliefs, attitudes and practices of front-line staff in long-term care (LTC) facilities related to osteoporosis awareness, management and fracture prevention? BMC Geriatrics. 2010;10:73.

Orwoll ES, Miller PD, Adachi JD, Jacques Brown J, Adler R, Kendler D, Bucci-Rechtweg C, Readie A, Mesenbrink P, Weinstein R. Efficacy and safety of a once-yearly i.v. infusion of zoledronic acid 5 mg versus a once-weekly 70 mg oral alendronate in the

treatment of male osteoporosis: a randomized, multicenter, dou-ble-blind, active-controlled study. J Bone Miner Res. 2010;25:2239-50.

Adachi JD, Adami S, Gehlbach S, Anderson Jr FA, Boonen S, Chapurlat RD, Compston JE, Cooper C, Delmas P, Díez-Pérez A, Greenspan SL, Hooven FH, LaCroix AZ, Lindsay R, Netelenbos JC, Wu O, Pfeilschifter J, Roux C, Saag KG, Sambrook PN, Silverman S, Siris ES, Nika G, Watts NB, for the GLOW Investigators. Impact of Prevalent Fractures on Quality of Life: Baseline results from the Global Longitudinal Study of Osteoporosis in Women. Mayo Clin Proceedings. 2010;85:806-13.

Langsetmo L, Morin S, Kovacs CS, Kreiger N, Josse R, Adachi JD, Papaioannou A, Goltzman D, Hanley DA, Olszynski WP, Prior J, Jamal SA. Determining whether women with osteopenic bone mineral density have low, moderate, or high clinical fracture risk. Menopause. 2010;17:1010-6.

Lau AN, Adachi JD. Role of teriparatide in treatment of gluco-corticoid-induced osteoporosis. Therapeutics and Clinical Risk Management. 2010;6:497-503.

Berger C, Goltzman D, Langsetmo L, Joseph L, Jackson S, Kreiger N, Tenenhouse A, Davison KS, Josse RG, Prior JC, Hanley DA, and the CaMos Research Group. Peak bone mass from longitudinal data: implications for the prevalence, pathophysiology and diag-nosis of osteoporosis. J Bone Miner Res. 2010;25:1948-57.

Langsetmo L, Leslie WD, Zhou W, Goltzman D, Kovacs CS, Prior JC, Josse RG, Olsyzynski WP, Davison KS, Anastassiades T, Towhead T, Hanley DA, Kaiser S, Kreiger N for the CaMos Research Group. Using the same bone density reference data-base for men and women provides a simpler estimation of frac-ture risk. J Bone Miner Res. 2010;25:2108-14.

Sawka AM, Ismaila N, Raina P, Thabane L, Straus S, Adachi JD, Gafni A, Papaioannou A. A survey of Canadian physicians’ opin-ions on hip fracture prevention strategies in long-term care. Can Fam Phys. 2010;56:e392-e397.

Quinton- Gladstone CL, Adachi JD, Greenwald E, Parasu N, Hotte SJ. Case Report : Celiac disease masquerading as bone metasta-ses in a 29 year old woman. J Clin Oncol. 2010;28:e623-e625.

Langsetmo L, Nguyen TV, Nguyen ND, Kovacs CS, Prior JC, Center JR, Morin S, Josse RG, Adachi JD, Hanley DA, Eisman JA and the Canadian Multicentre Osteoporosis Study Research Group. Independent external validation of nomograms for low trauma fracture and hip fracture risk in a population of Canadian men and women ages 55-95. CMAJ. 2010;183:200.

Szabo KA, Webber CE, Gordon C, Adachi JD, Tozer R, Papaioannou A. Reproducibility of peripheral quantitative comput-ed tomography measurements at the radius and tibia in healthy pre- and postmenopausal women. Can Assoc Radiol J. 2011 Aug;62(3):183-9. Epub 2010 Jun 23.

ANAND, S.Rafiq S, Anand SS, Roberts R. Genetics of Hypertension: Genome wide association studies of hypertension: Have they been fruitful? J Cardiovasc Transl Res. 2010 Jan;3(3):189-96.

Chow CK, Jolly S, Rao-Melacini P, Fox KA, Anand SS, Yusuf S. Association of diet, exercise, and smoking modification with risk of early cardiovascular events after acute coronary syndromes. Circulation. 2010 Feb 16;121(6):750-8.

Lanktree M, Anand SS, Yusuf S, Hegele R, on behalf of the SHARE Investigators. Comprehensive analysis of genomic variation in the LPA locus and its relationship to plasma lipoprotein(a) in South

PublicationsHamilton Health SciencesMurray Martin President and CEOTeresa Smith VP of Patient ServicesRichard McLean VP, Medical Affairs & QualityBrenda Flaherty Executive VP, Clinical OperationsNancy Fram VP, Professional AffairsMurray Glendining Executive VP, Corporate AffairsLouise Taylor Green VP, Human Resources and Organizational DevelopmentKathy Watts VP, Finance and CFOBarry Lumb Chief of MedicineSalim Yusuf VP, Research

Thrombosis & Atherosclerosis Research Institute (TaARI)Jeff Weitz Director

Juravinski Cancer CentreWilliam Evans President

McMaster Children’s HospitalPeter Fitzgerald President

St. Peter’s HospitalDonna Cripps President

St. Joseph’s HealthcareKevin Smith President and CEODavid Higgins PresidentWinnie Doyle VP, Clinical ServicesRomeo Cercone VP, Quality and Strategic PlanningSusan Hollis VP, Business and Therapeutic ServicesDiana Elder Chief Human Resources OfficerHugh Fuller VP, Medical and Academic AffairsDavid Russell Chief, Medicine

Father Sean O’Sullivan Research CentreIan Rodger Director

Affiliated Centres

122

PUBLICATIONS

Kanwal F, Barkun A, Gralnek IM, Asch SM, Kuipers EJ, Bardou M, Sung J, Enns R, Agreus L, Armstrong D, Spiegel BMR. Measuring quality of care in patients with non-variceal upper gastrointestinal hemorrhage: development of an explicit quality indicator set. Am J Gastroenterol. 2010;105:1710-8.

Moayyedi P, Armstrong D, Hunt RH, Lei Y, Bukoski M, White RJ. The gain in quality adjusted life years by switching to esomepra-zole in those with continued reflux symptoms in primary care: EncomPASS – a cluster-randomized trial. Am J Gastroenterol. 2010;105:2341-6.

Tarnopolsky MA, Pearce E, Matalliano A, James C, Armstrong D. Small bowel bacterial overgrowth syndrome in myotonic mus-cular dystrophy is a potentially treatable entity. Muscle Nerve. 2010;42:853-5.

ARNOLD, D.Choong K, Cupido C, Nelson E, Arnold DM, Burns K, Cook DJ, Meade MO on behalf of ACCADEMY (Academy of Critical Care: Development, Evaluation, and Methodology, McMaster University). A Framework for resolving disagreement during end of life care in the critical care unit. Clinical Investigative Medicine. 2010 Aug 1;33(4):E240-53.

Rodeghiero F, Tosetto A, Abshire T, Arnold DM, Coller B, James P, Neunert C, Lillicrap D; on behalf of the ISTH/SSC Joint VWF and Perinatal/Pediatric Hemostasis Subcommittees Working Group. ISTH/SSC bleeding assessment tool: a standardized questionnaire and a proposal for a new bleeding score for inherited bleeding disorders. J Thromb Haemost. 2010 Sep;8(9):2063-5.

Arnold DM, Crowther MA, Meyer RM, Carruthers J, DiTomasso J, Heddle NM, McLeod A, Kelton JG. Misleading Hepatitis B Test Results Due to Intravenous Immunoglobulin Administration: Implications for a Clinical Trial of Rituximab in Immune Thrombocytopenia. Transfusion. 2010 Dec;50(12):2577-81.

Fry JL, Arnold DM, Clase CM, Crowther MA, Holbrook AM, Traore AN, Warkentin TE, Heddle NM. Transfusion premedication to prevent acute transfusion reactions: a retrospective obser-vational study to assess current practices. Transfusion. 2010 Aug;50(8):1722-30.

Arnold DM, Anderson J, Kearon C. Preoperative evaluation of bleeding and thromboembolism risk. Praxis (Bern 1994). 2010 May 12;99(10):609-12.

Cooper N, Arnold DM. The effect of rituximab on humoral and cell mediated immunity and infection in the treatment of autoimmune diseases. Br J Haematol. 2010 Apr;149(1):3-13.

Arnold DM, Nazi I, Santos A, Chan, H, Heddle NM, Warkentin TE, Kelton JG. Combination immunosuppressant therapy for patients with chronic refractory immune thrombocytopenic purpura. Blood. 2010 Jan 7;115(1)29-31.

ASK, K.Ask K, Eickelberg O, Gauldie J, Kaminski N, Kolb M. Have advanced research technologies made real impact on respiratory medicine? Respirology. 2010;15(6):876-80.

Rodt T, von Falck C, Dettmer S, Halter R, Maus R, Ask K, Kolb M, Gauldie J, Langer F, Hoy L, Welte T, Galanski M, Maus UA, Borlak J. Micro-computed tomography of pulmonary fibrosis in mice induced by adenoviral active transforming growth factor-b1. Resp Res. 2010;Dec 22;11(1):181.

BADER, M.Bader MS, Hawboldt J. Antibiotic prescribing and antimicrobial resistance. Postgrad Med. 2010 Jul;122(4):227-9.

Bader MS, Hawboldt J, Brooks A. Management of complicated urinary tract infections in the era of antimicrobial resistance. Postgrad Med. 2010 Nov;122(6):7-15.

BAKER, S.Staples AW, Burd NA, West DWD, Currie K, Atherton PJ, Moore DR, Rennie MJ, MacDonald MJ, Baker SK, Phillips SM. Carbohydrate does not augment exercise-induced protein accre-tion versus protein alone. Med Sci Sports Exerc. 2010 Dec 1. [Epub ahead of print]

Burd NA, West D, Staples AW, Atherton P, Baker SK, Baker JM, Parise G, Rennie M, Moore D, Holwerda A. Low-load high volume resistance exercise stimulates muscle protein synthesis more than high-load low volume resistance exercise in young men. PLoS One. 2010 Aug 9;5(8):e12033.

Burd NA, Holwerda AM, Selby KC, West DWD, Staples AW, Cain NE, Cashaback JG, Potvin JR, Baker SK, Phillips, SM. Resistance exercise volume affects myofibrillar protein synthesis and anabolic signaling molecule phosphorylation in young men. J Physiol. 2010 Aug 15;588(Pt 16):3119-30. Epub 2010 Jun 25.

MacNeil LG, Melov S, Hubbard AE, Baker SK, Tarnopolsky MA. Eccentric Exercise Activates Novel Transcriptional Regulation of Hypertrophic Signaling Pathways Not Affected by Hormone Changes. PLoS One. 2010 May 18;5(5):e10695.

Baker, SK, Lipson, D. Vincristine-Induced Peripheral Neuropathy in a Neonate with Congenital Acute Lymphoblastic Leukemia. J Pediatr Hematol Oncol. 2010 Apr;32(3):e114-7.

BATES, S.Spencer FA, Bates SM, Goldberg RJ, Lessard D, Emery C, Glushchenko A, Gore JM, Pacifico L, White RH. A population-based study of inferior vena caval filters in patients diagnosed with acute venous thromboembolism. Arch Intern Med. 2010;170:1456-62.

Sardo LA, Stevens PB, Bates SM. Nursing Perspective: Informed consent and patient empowerment. e-thrombosis. December 2010.

Bates SM. Consultative hematology: the pregnant patient – preg-nancy loss. Hematol. 2010;166-72.

Douketis JD, Julian JA, Crowther MA, Kearon C, Bates SM, Barone M, Piovella F, Middeldorp S, Prandoni P, Johnston M, Costantini L, Ginsberg JS. The effect of prothrombotic blood abnormalities on risk of deep vein thrombosis in users of hormone replacement therapy: a prospective case-control study. Clin Appl Thromb Hemost. Epub 2010 Dec 15.

BEATTIE, K.Inglis D, Wong AKO, Eckstein F, Adachi JD, Beattie KA. Multi-Planar Reconstruction Recovers Morphological Cartilage Assessment Reproducibility from Mal-oriented Coronal MRI Scans. Magnetic Resonance in Medicine. 2010;65(3):790-5.

BERCIK, P.Xenodemetropoulos T, Khan KJ, Bercik P. Spontaneous Intramural Esophageal Hematoma in Association With Idiopathic Thrombocytopenic Purpura: A Cause of Non-Cardiac Chest Pain. Clin Gastroenterol Hepatol. 2010 Jul;8(7):e73-4.

Bercik P, Verdu EF, Foster JA, Macri J, Potter M, Huang X, Malinowski P, Jackson W, Blennerhassett P, Neufeld KA, Lu J, Khan WI, Corthesy-Theulaz I, Cherbut C, Bergonzelli GE, Collins SM. Chronic gastrointestinal inflammation induces anxiety-like behavior and alters central nervous system biochemistry in mice. Gastroenterology. 2010;139(6):2102-12.

BRAGA, M.Teoh H, Braga MF, Casanova A, Drouin D, Goodman SG, Harris SB, Langer A, Tan MK, Ur E, Yan AT, Zinman B, Leiter LA; on behalf of the T2DM QUERI Investigators. Time 2 Do More Quality

Asians, Chinese and European Caucasians. Circ Cardiovasc Genet. 2010 Feb 1;3(1):39-46.

Pare G, Anand SS. Mendelian randomisation, triglycerides, and CHD. Lancet. 2010 May 8;375(9726):1584-6.

Grewal K, Leung YW, Safai P, Stewart DE, Anand S, Gupta M, Parsons C, Grace SL. Access to cardiac rehabilitation among South-Asian patients by referral method: a qualitative study. Rehabil Nurs. 2010 May-June;35(3):106-12.

Mente A, Yusuf S, Islam S, McQueen MJ, Tanomsup S, Onen CL, Rangarajan S, Gerstein HC, Anand SS; INTERHEART Investigators. Metabolic syndrome and risk of acute myocardial infarction a case-control study in 26,903 subjects from 52 countries. J Am Coll Cardiol. 2010 May 25;55(21):2390-8.

Kreatsoulas C, Natarajan MK, Khatun R, Velianou JL, Anand SS. Identifying women with severe angiographic coronary disease. J Intern Med. 2010 Jul;268(1):66-74.

de Koning L, Gerstein H, Bosch J, Diaz R, Mohan V, Dagenais G, Yusuf S, Anand S, for the EpiDREAM investigators. Anthropometric measures and glucose levels in a large multi-ethnic cohort of individuals at risk of developing type 2 diabetes. Diabetologia. 2010 Jul;53(7):1322-30.

Mente A, Razak F, Blankenberg S, Vuksan V, Davis AD, Miller R, Teo K, Gerstein H, Sharma AM, Yusuf S, Anand SS; Study of the Health Assessment and Risk Evaluation; Study of the Health Assessment and Risk Evaluation in Aboriginal Peoples Investigators. Ethnic variation in adiponectin and leptin levels and their association with adiposity and insulin resistance. Diabetes Care. 2010 Jul;33(7):1629-34.

Lanktree MB, Johansen CT, Anand SS, Davis AD, Miller R, Yusuf S, Hegele RA. Genetic variation in hyaluronan metabolism loci is associated with plasma plasminogen activator inhibitor-1 concen-tration. Blood. 2010 Sep 23;116(12):2160-3.

Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S; on behalf of the DREAM investigators. Variation at the NFATC2 Locus Increases the Risk of Thizolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. Diabetes Care. 2010 Oct;33(10):2250-3.

Yusuf S, Anand SS. Deciphering the causes of cardiovascular and other complex diseases in populations: Achievements, challenges, opportunities and approaches. Prog Cardiovasc Dis. 2010;53(1):62-7.

Johansen CT, Wang J, Lanktree MB, Cao H, McIntyre AD, Ban MR, Martins RA, Kennedy BA, Hassell RG, Visser ME, Schwartz SM, Voight BF, Elosua R, Salomaa V, O’Donnell CJ, Dallinga-Thie GM, Anand SS, Yusuf S, Huff MW, Kathiresan S, Hegele RA. Excess of rare variants in genes indentified by genome-wide association study of hypertriglyceridemia. Nat Genet. 2010 Aug;42(8):648-7.

Anand SS, Yusuf S. C-reactive protein is a bystander for cardiovas-cular disease. Eur Heart J. 2010 Sep;31(17):2092-6.

Pare G, Mehta SR, Yusuf S, Anand SS, Connolly SJ, Hirsh J, Simonsen K, Bhatt DL, Fox KA, Eikelboom JW. Effects of CYP2C19 genotype on outcomes of clopidogrel treatment. N Engl J Med. 2010 Oct 28;363(18):1704-14.

Gerstein HC, Islam S, Anand S, Almahmeed W, Damasceno A, Dans A, Lang CC, Luna MA, McQueen M, Rangarajan S, Rosengren A, Wang X, Yusuf S. Dysglycaemia and the risk of acute myocardial infarction in multiple ethnic groups: an analysis of 15,780 patients from the INTERHEART study. Diabetologia. 2010 Dec;53(12):2509-17.

Do R, Bailey SD, Paré G, Montpetit A, Desbiens K, Hudson TJ, Yusuf S, Bouchard C, Gaudet D, Pérusse L, Anand S, Vohl MC, Pastinen T, Engert JC. Fine mapping of the insulin-induced gene 2 identifies a variant associated with LDL cholesterol and total apoli-poprotein B levels. Circ: Cardiovasc Genet. 2010 Oct 1;3(5):454-61.

Kreatsoulas C, Sloane D, Pogue J, Velianou JL, Anand SS. Referrals in Acute Coronary Events for CARdiac Catheterization: The RACE CAR Trial. Can J Cardiol. 2010 Oct 26;(8):290-6.

Kreatsoulas C, Anand SS. The Impact of Social Determinants on Cardiovascular Disease. Can J Cardiol. 2010 Aug-Sept;26 Suppl C:8C-13C.

Boyko J, Gerstein H, Mohan V, Yusuf S, Sheridan P, Anand S, Shaw J, for DREAM Trial Investigators. Effects of ethnicity on diabetes incidence and prevention: results of the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) trial. Diabet Med. 2010 Nov;27(11):1226-32.

Assimes T, Holm H, Kathiresan S, Reilly M, Thorleifsson G, Voight B, et al. Lack of Association Between the Trp719Arg Polymorphism in Kinesin-Like Protein-6 and Coronary Artery Disease in 19 Case-Control Studies. J Am Coll Cardiol. 2010 Nov 2;56(19):1552-63.

Sun JC, Teoh KH, Lamy A, Sheth T, Ellins ML, Jung H, Yusuf S, Anand S, Connolly S, Whitlock RP, Eikelboom JW. Randomized trial of aspirin and clopidogrel versus aspirin alone for the prevention of coronary artery bypass graft occlusion: the Preoperative Aspirin and Postoperative Antiplatelets in Coronary Artery Bypass Grafting study. Am Heart J. 2010 Dec;160(6):1178-84.

Khan SN, Grace SL, Oh P, Anand S, Stewart DE, Wu G, Gupta M. A comparison of physical activity environments between South Asians and white Caucasians with coronary heart disease. Ethnicity and Disease. 2010;20(4);390-5.

ANDERSON, J.Teh CH, Robertson MN, Warkentin TE, Henriksen PA, Brackenbury ET, Anderson JAM. Transient Global Amnesia as the First Presenting Feature of Heparin-induced Thrombocytopenia. Journal of Cardiothoracic Surgery. 2010 May;25(3)300-2.

Shaikhrezai K, Bashir U, Millar S, Anderson J, Brackenbury ET. Redo-redo aortic root replacement with a mechanical valved conduit in a patient with von Willebrand’s disease: Case report. J Cardiothorac Surg. 2010 Aug13;5:59.

Anderson JA, Weitz JI. Hypercoagulable States. Clin Chest Med. 2010 Dec 31(4):659-73. Epub 2010 Aug 11.

Anderson JAM, Thomas AE. Investigation of easy bruising in a child. BMJ. 2010 Oct 11;341:c4565.

ARMSTRONG, D.Cohen H, Tomasso G, Cafferata ML, Zapata C, Sharma P, Armstrong D, Moraes-Filho JP, Blasco C, Corti R, Estape G, Luna LL, Ortuño R, Sakai P, Salis G, Taullard D, Trakal E, Valdovinos M, Vergara M, Gónzalez O. Latin American Consensus on Gastroesophageal Reflux Disease: An Update on Therapy. Gastroenterol Hepatol. 2010;33(2):135-47.

Barkun AN, Crott R, Fallone CA, Kennedy WA, Lachaine J, Levinton C, Armstrong D, Chiba N, Thomson AB, Veldhuyzen van Zanten SJO, Escobedo S, Chakraborty B, Smyth S, White R, Kalra H, Nevin K. The economic evaluation over one year of six alternative strategies in the management of uninvestigated upper gastroin-testinal symptoms in Canadian primary care. Can J Gastroenterol. 2010;24(8):489-98.

Hunt RH, Armstrong D, Yaghoobi M, James C. Pharmacodynamics and pharmacokinetics of S-tenatoprazole-Na 30 mg, 60 mg and 90 mg versus esomeprazole 40 mg in healthy male subjects. Aliment Pharmacol Ther. 2010;31:648-57.

Gramlich LM, Olstad DL, Nasser R, Goonewardene L, Raman M, Innis S, Wicklum S, Duerksen D, Rashid M, Heyland D, Armstrong D, Roy C. Medical students’ perceptions of nutrition in Canadian universities. Appl Physiol Nutr Metab. 2010;35:336-43.

124

PUBLICATIONS

Motomura Y, Khan WI, El-Sharkawy RT, Verma-Gandhu M, Grencis RK, Collins SM. Mechanisms Underlying Gut Dysfunction in a Murine Model of Chronic Parasitic Infection. Am J Physiol Gastrointest Liver Physiol. 2010 Dec;299(6):G1354-60.

Shanahan F, Collins SM. Pharmabiotic manipulation of the microbiota in gastrointestinal disorders, from rationale to reality. Gastroenterol Clin North Am. 2010 Sep;39(3):721-6.

Bienenstock J, Collins SM. 99th Dahlem conference on infection, inflammationand chronic inflammatory disorders: psycho-neuroim-munology and the intestinal microbiota: clinical observations and basic mechanisms. Clin Exp Immunol. 2010Apr;160(1):85-91.

CONNOLLY, S.Nieuwlaat R, Barker L, Kim YK, Haynes RB, Eikelboom JW, Yusuf S, Connolly SJ. Underuse of Evidence-based warfarin dosing meth-ods for atrial fibrillation patients. Thorm Res. 2010;125(4):e128-31.

Nery P, Fernandes R, Nair G, Ribas C, Divakaramenon S, Wang X, Krahn A, Morillo C, Connolly S, Healey J. J Cardiovasc Electrophysiology. 2010;21(7):786-90.

Eikelboom JW, Wallentin L, Yusuf S, Ezekowitz MD, Reilly PA, Brueckmann M, Clemens A, Connolly SJ. Does dabigatran improve stroke-prevention in atrial fibrillation? J Thromb Haemost. 2010; Feb 9.

Eikelboom JW, O’Donnell M, Yusuf S, Diaz R, Flaker G, Hart R, Hohnloser S, Joyner C, Lawrence J, Pais P, Pogue J, Synhorst D, Connolly SJ. Rationale and design of AVERROES: apixaban versus acetylsalicylic acid to prevent stroke in atrial fibrillation patients who have failed or are unsuitable for vitamin K. Am Heart J. 2010;159(3):348-53.

Flaker GC, Pogue J, Yusuf S, Pfeffer MA, Goldhaber SZ, Granger CB, Anand IS, Hart R, Connolly SJ; for the Atrial Fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events (ACTIVE) Investigators. Cognitive Function and Anticoagulation Control in Patients with Atrial Fibrillation. Circ Cardiovasc Qual Outcomes. 2010;3(3):277-83.

Talajic M, Khairy P, Levesque S, Connolly SJ, Dorian P, Dubuc M, Guerra PG, Hohnloser SH, Lee KL, Macle L, Nattel S, Pedersen OD, Stevenson LW, Thibault B, Waldo AL, Wyse DG, Roy D. Maintenance of sinus rhythm and survival in patients with heart failure and atrial fibrillation. J Am Coll Cardiol. 2010;55(17):1796-802.

Healey JS, Dorian P, Mitchell LB, Talajic M, Philippon F, Simpson C, Yee R, Morillo CA, Lamy A, Basta M, Birnie DH, Wang X, Nair GM, Crystal E, Kerr CR, Connolly SJ; on Behalf of the CREDIT Investigators. Canadian Registry of ICD Implant Testing Procedures (CREDIT): Current Practice, Risks, and Costs of Intraoperative Defibrillation Testing. J Cardiovasc Electrophysiol. 2010;21(2):177-82.

Kim YK, Nieuwlaat R, Connolly SJ, Schulman S, Meijer K, Raju N, Kaatz S, Eikelboom JW. Effect of a simple two-step warfarin dosing algorithm on anticoagulant control as measured by time-in thera-peutic range: a pilot study. J Thromb Haemost. 2010;8(1):101-6.

Andrade JG, Connolly SJ, Dorian P, Green M, Humphries KH, Klein GJ, Sheldon R, Talajic M, Kerr CR. Antiarrhythmic use from 1991 to 2007: Insights from the Canadian Registry of Atrial Fibrillation (CARAF I and II). Heart Rhythm. 2010;7(9):1171-7.

Hohnloser SH, Crijns HJ, van Eickels M, Gaudin C, Page RL, Torp-Pedersen C, Connolly SJ; for the ATHENA Investigators. Dronedarone in patients with congestive heart failure: insights from ATHENA. Eur Heart J. 2010;31(14):1717-21.

De Caterina R, Connolly SJ, Pogue J, Chrolavicius S, Budag A, Morais J, Renda G, Yusuf S; on behalf of the ACTIVE Investigators. Mortality predictors and effects of antithrombotic therapies in atrial fibrillation: insights from ACTIVE-W. Eur Heart J. 2010;31(17):2133-40.

Nieuwlaat R, Connolly SJ. ACP Journal Club. Lenient rate control is as effective as strict rate control for preventing cardiovascular events in AF. Ann Intern Med. 2010;153(4):JC2-4.

Weitz JI, Connolly SJ, Patel I, Salazar D, Rohatagi S, Mendell J, Kastrissios H, Jin J, Kunitada S. Randomised, parallel-group, multi-centre, multinational phase 2 study comparing edoxaban, an oral factor Xa inhibitor, with warfarin for stroke prevention in patients with atrial fibrillation. Thromb Haemost. 2010;104(3):633-41.

Healey JS, Birnie DH, Lee DS, Krahn AD, Crystal E, Simpson CS, Dorian P, Chen Z, Cameron D, Verma A, Connolly SJ, Gula LJ, Lockwood E, Nair G, Tu JV; on behalf of the Ontario ICD Database Investigators. Defibrillation Testing at the Time of ICD Insertion: An Analysis from the Ontario ICD Registry. J Cardiovasc Electrophysiol. Epub 2010 Jul 19.

Healey JS, Nair GM, Connolly SJ, Morillo CA. A rare cause of implantable cardioverter-defibrillator failure: Short-circuiting via an unused pace/sense lead. Heart rhythm. 2010;7(11):1630-1.

Wallentin L, Yusuf S, Ezekowitz MD, Alings M, Flather M, Franzosi MG, Pais P, Dans A, Eikelboom J, Oldgren J, Pogue J, Reilly PA, Yang S, Connolly SJ; on behalf of the RE-LY investigators. Efficacy and safety of dabigatran compared with warfarin at different levels of international normalized ratio control for stroke preven-tion in atrial fibrillation: an analysis of the RE-LY trial. Lancet. 2010;376:975-83.

Connolly SJ, Hohnloser SH. Dronedarone for atrial fibrillation have we expanded antiarrhythmic armanmentarium? J Am Coll Cardiol. 2010;56(16):1353-4.

Pare G, Mehta SR, Yusuf S, Anand SS, Connolly SJ, Hirsh J, Simonsen K, Bhatt DL, Fox KA,

Eikelboom JW. Effects of CYP2C19 genotype on outcomes of clopi-dogrel treatment. N Engl J Med. 2010;363(18):1704-14.

Connolly SJ, Ezekowitz MD, Yusuf S, Reilly PA, Wallentin L; Randomized Evaluation of Long-Term Anticoagulation Therapy Investigators. Newly identified events in the RE-LY trial. N Engl J Med. 2010;363(19):1875-6.

Diener HC, Connolly SJ, Ezekowitz MD, Wallentin L, Reilly PA, Yang S, Xavier D, Di Pasquale G, Yusuf S; RE-LY study group. Dabigatran compared with warfarin in patients with atrial fibrillation and previ-ous transient ischaemic attack or stroke: a subgroup analysis of the RE-LY trial. Lancet Neurol. 2010;9(12):1157-63.

Dorian P, Hohnloser SH, Thorpe KE, Roberts RS, Kuck KH, Gent M, Connolly SJ. Mechanisms underlying the lack of effect of implantable cardioverter-defibrillator therapy on mortality in high-risk patients with recent myocardial infarction: insights from the Defibrillation in Acute Myocardial Infarction Trial (DINAMIT). Circulation. 2010;122(25):2645-52.

Ezekowitz MD, Wallentin L, Connolly SJ, Parekh A, Chernick MR, Pogue J, Aikens TH, Yang S, Reilly PA, Lip GY, Yusuf S; RE-LY Steering Committee and Investigators. Dabigatran and warfarin in vitamin K antagonists-naïve and -experienced cohorts with atrial fibrillation. Circulation. 2010;122(22):2246-53.

Sun JC, Teoh KH, Lamy A, Sheth T, Ellins ML, Jung H, Yusuf S, Anand S, Connolly S, Whitlock RP, Eikelboom JW. Randomized trial of aspirin and clopidogrel versus aspirin alone for the prevention of coronary artery bypass graft occlusion: the Preoperative Aspirin and Posteroperative Antiplatelets in Coronary Artery Bypass Grafting study. Am Heart J. 2010;160(6):1178-84.

Tang AS, Wells GA, Talajic M, Arnold MO, Sheldon R, Connolly S, Hohnloser SH, Nichol G, Birnie DH, Sapp JL, Yee R, Healey JS, Rouleau JL; Resynchronization-Defibrillation for Ambulatory Heart Failure Trial Investigators. Cardiac-resynchronization therapy for mild-to-moderate heart failure. N Engl J Med. 2010;363(25):2385-95.

Cairns JA, Yusuf S, Cook RJ, Cox J, Dagenais GR, Devereaux PJ, McAlister FA, McCready T; CANNeCTIN. Canadian Network and Centre for Trials Internationally (CANNeCTIN): a national network

Enhancement Research Initiative (T2DM QUERI): Patient age, ethnicity, medical history and risk factor profile, but not drug insur-ance coverage, predict successful attainment of glycemic targets. Diabetes Care. 2010 Dec;33(12):2558-60. Epub 2010 Sep 7.

Braga M, Casanova A, Teoh H, Dawson KC, Gerstein HC, Fitchett DH, Harris SB, Honos G, McFarlane PA, Steele A, Ur E, Yale JF, Langer A, Goodman SG, Leiter LA; Diabetes Registry to Improve Vascular Events (DRIVE) Investigators. Treatment gaps in the management of cardiovascular risk factors in patients with type 2 diabetes in Canada. Can J Cardiol. 2010 Jun;26(6):297-302.

Gupta M, Szmitko PE, Tsigoulis M, Braga MF, Kajil M, Herjikaka S, Quan A, Teoh H, Verma S. Effects of ezetimibe add-on to statin therapy on adipokine production in patients with metabolic syn-drome and stable vascular disease. J Cardiovasc Pharmacol. 2010 Sep;56(3):241-5.

BULLER, C.Kruk M, Buller CE, Tcheng JE, Dzavík V, Menon V, Mancini GB, Forman SA, Kurray P, Busz-Papiez B, Lamas GA, Hochman JS. Impact of left ventricular ejection fraction on clinical outcomes over five years after infarct-related coronary artery recanaliza-tion (from the Occluded Artery Trial [OAT]). Am J Cardiol. 2010 Jan 1;105(1):10-6.

Jorapur V, Lamas GA, Sadowski ZP, Reynolds HR, Carvalho AC, Buller CE, Rankin JM, Renkin J, Steg PG, White HD, Vozzi C, Balcells E, Ragosta M, Martin CE, Srinivas VS, Wharton Iii WW, Abramsky S, Mon AC, Kronsberg SS, Hochman JS. Renal impair-ment and heart failure with preserved ejection fraction early post-myocardial infarction. World J Cardiol. 2010 Jan 26;2(1):13-8.

Toma M, Buller CE, Westerhout CM, Fu Y, O’Neill WW, Holmes DR Jr, Hamm CW, Granger CB, Armstrong PW; APEX-AMI Investigators. Non-culprit coronary artery percutaneous coro-nary intervention during acute ST-segment elevation myocardial infarction: insights from the APEX-AMI trial. Eur Heart J. 2010 Jul;31(14):1701-7.

Steg PG, Kerner A, Mancini GB, Reynolds HR, Carvalho AC, Fridrich V, White HD, Forman SA, Lamas GA, Hochman JS, Buller CE; OAT Investigators. Impact of collateral flow to the occluded infarct-related artery on clinical outcomes in patients with recent myocardial infarction: a report from the randomized occluded artery trial. Circulation. 2010 Jun 29;121(25):2724-30.

Hiratzka LF, Bakris GL, Beckman JA, Bersin RM, Carr VF, Casey DE Jr, et al. 2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM Guidelines for the diagnosis and management of patients with tho-racic aortic disease: Executive summary: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, American Association for Thoracic Surgery, American College of Radiology, American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons, and Society for Vascular Medicine.American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines; American Association for Thoracic surgery; American College of Radiology; American Stroke Association; Society of Cardiovascular Anesthesiologists; Society for Cardiovascular Angiography and Interventions; Society of Interventional Radiology; Society of Thoracic Surgeons; Society for Vascular Medicine. Anesth Analg. 2010 Aug;111(2):279-315.

Steigen TK, Buller CE, Mancini GB, Jorapur V, Cantor WJ, Rankin JM, Thomas B, Webb JG, Kronsberg SS, Atchison DJ, Lamas GA, Hochman JS, Dzavík V. Myocardial Perfusion Grade After Late Infarct Artery Recanalization Is Associated With Global and Regional Left Ventricular Function at One Year: Analysis From the Total Occlusion Study of Canada-2. Circ Cardiovasc Interv. 2010 Dec;3(6):549-55.

Greenland P, Alpert JS, Beller GA, Benjamin EJ, Budoff MJ, Fayad ZA, Foster E, Hlatky MA, Hodgson JM, Kushner FG, Lauer MS,

Shaw LJ, Smith SC Jr, Taylor AJ, Weintraub WS, Wenger NK, Jacobs AK, Smith SC Jr, Anderson JL, Albert N, Buller CE, Creager MA, Ettinger SM, Guyton RA, Halperin JL, Hochman JS, Kushner FG, Nishimura R, Ohman EM, Page RL, Stevenson WG, Tarkington LG, Yancy CW; American College of Cardiology Foundation; American Heart Association. 2010 ACCF/AHA guideline for assess-ment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2010 Dec 14;56(25):e50-103.

CHIBA, N.Barkun AN, Bardou M, Kuipers EJ, Sung J, Hunt RH, Martel M, Sinclair P, International Consensus Upper Gastrointestinal Bleeding Conference Group. International consensus recommen-dations on the management of patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med. 2010;152:101-13.

Barkun AN, Crott R, Fallone CA, Kennedy WA, Lachaine J, Levinton C, Armstrong D, Chiba N, Thomson ABR, Veldhuyzen van Zanten SJO, Sinclair P, Escobedo S, Chakraborty B, Smyth S, White R, Kalra H, Nevin K. The economic evaluation over one year of six alternative strategies in the management of uninvestigated upper gastrointestinal symptoms in Canadian primary care. Can J Gastroenterol. 2010 Aug;24(8):489-98.

CLARK, D.Clark DA. Anti-TNF-a therapy in immune-mediated subfertility: state of the art. J Reprod Immunol. 2010 May;85:15-24.

Clark DA, Chaouat G, Wong K, Gorczynski RM, Kinsky R. Tolerance mechanisms in pregnancy: a reappraisal of the role of Class I paternal MHC antigens. Amer J Reprod Immunol. 2010;63:93-103.

Foerster K, Zhu Y, Helmy A, Khattar R, Adeyi OA, Wong KM, Shalev I, Clark DA, Wong P-Y, Heathcoate EJ, Phillips MJ, Grant DR, Renner EL, Levy GA, Slezner N. The novel immunoregulatory mol-ecule FGL2: a potential biomarker for severity of chronic hepatitis C virus. J Hepatology. 2010;53:608-15.

COLLINS, S.Villani AC, Lemire M, Thabane M, Belisle A, Geneau G, Garg AX, Clark WF, Moayyedi P, Collins SM, Franchimont D, Marshall JK. Genetic Risk Factors for Post-Infectious Irritable Bowel Syndrome Following a Waterborne Outbreak of Gastroenteritis. Gastroenterology. 2010 Apr;138(4):1502-13.

Ford AC, Thabane M, Collins SM, Moayyedi P, Garg AX, Clark WF, Marshall JK. Prevalence of Uninvestigated Dyspepsia 8 Years After a Large Waterborne Outbreak of Bacterial Dysentery: Cohort Study. Gastroenterology. 2010 May;138(5):1727-36; quiz e12.

Thabane M, Simunovic M, Akhtar-Danesh N, Garg AX, Clark WF, Collins SM, Salvadori M, Marshall JK. Am J Gastroenterol. 2010 Apr;105(4):933-9.

Marshall JK, Thabane M, Garg AX, Clark WF, Moayyedi P, Collins SM; Walkerton Health Study Investigators. Eight year prognosis of postinfectious irritable bowel syndrome following waterborne bacterial dysentery. Gut. 2010 May;59(5):605-11.

Bercik P, Verdu EF, Foster JA, Macri J, Potter M, Huang X, Malinowski P, Jackson W, Blennerhassett P, Neufeld KA, Lu J, Khan WI, Corthesy-Theulaz I, Cherbut C, Bergonzelli GE, Collins SM. Chronic Gastrointestinal Inflammation Induces Anxiety-Like Behavior and Alters Central Nervous System Biochemistry in Mice. Gastroenterology. 2010 Dec;139(6):2102-12.e1.

Hall GB, Kamath MV, Collins SM, Ganguli S, Spaziani R, Miranda KL, Bayati A, Bienenstock J. Heightened central affective response to visceral sensations of pain and discomfort in IBS. Neurogastroenterol Motil. 2010 Mar;22(3):276-e80.

126

PUBLICATIONS

Management Program of Ontario coagulation surveys. J Thromb Haemost. 2010 Oct;104(4):837-44.

Donadini MP, Crowther M. Antiphospholipid syndrome: a challeng-ing hypercoagulable state with systemic manifestations. Hematol Oncol Clin North Am. 2010 Aug;24(4):669-76, vii.

Crowther M, Lim W, Crowther MA. Systematic review and meta-analysis methodology. Blood. Epub 2010 Jul 23.

Goldenberg NA, Donadini MP, Kahn SR, Crowther M, Kenet G, Nowak-Gottl U, Manco-Johnson MJ. Post thrombotic syndrome in children: a systematic review of frequency of occurrence, valid-ity of outcome measures, and prognostic factors. Haematologica. Epub 2010 Jun 30.

Rodger MA, Le Gal G, Carrier M, Betancourt MT, Kahn SR, Wells PS, Anderson DA, Lacut K, Chagnon I, Solymoss S, Crowther M, Perrier A, White R, Vickars L, Ramsay T, Kovacs MJ. Serum lipo-protein (a) levels in patients with first unprovoked venous thrombo-embolism is not associated with subsequent risk of recurrent VTE. Thromb Res. 2010 Sep;126(3):222-6.

Arnold DM, Crowther MA, Meyer RM, Carruthers J, Ditomasso J, Heddle NM, McLeod A, Kelton JG. Misleading hepatitis B test results due to intravenous immunoglobulin administration: implica-tions for a clinical trial of rituximab in immune thrombocytopenia. Transfusion. 2010 Dec;50(12):2577-81.

Kovacs MJ, Kahn SR, Wells PS, Anderson DA, Chagnon I, Le Gal G, Solymoss S, Crowther M, Perrier A, Ramsay T, Betancourt MT, Rodger MA. Patients with a first symptomatic unprovoked DVT are at higher risk of recurrent VTE than patients with a first unpro-voked PE. J Thromb Haemost. Epub 2010 Jun 19.

Le Gal G, Kovacs MJ, Carrier M, Do K, Kahn SR, Wells PS, Anderson DA, Chagnon I, Solymoss S, Crowther M, Righini M, Lacut K, White RH, Vickars L, Rodger M. Risk of recurrent venous thromboembolism after a first oestrogen-associated episode. Data from the REVERSE cohort study. Thromb Haemost. 2010 Sep;104(3):498-503.

Papaioannou A, Kennedy CC, Campbell G, Stroud JB, Wang L, Dolovich L, Crowther MA; Improving Prescribing in Long Term Care Investigators. A team-based approach to warfarin management in long term care: a feasibility study of the MEDeINR electronic deci-sion support system. BMC Geriatr. 2010 Jun 10;10:38.

Tincani E, Crowther MA, Bernardini A, Foroni M. Surveillance duplex scanning to prevent venous thromboembolism: does it make a difference in rehabilitation unit patients? J Thromb Haemost. 2010 Aug;8(8):1872-4.

Douketis JD, Julian JA, Crowther MA, Kearon C, Bates SM, Barone M, Piovella F, Middeldorp S, Prandoni P, Johnston M, Costantini L, Ginsberg JS. The Effect of Prothrombotic Blood Abnormalities on Risk of Deep Vein Thrombosis in Users of Hormone Replacement Therapy: A Prospective Case-Control Study. Clin Appl Thromb Hemost. Epub 2010 Dec 15.

Dentali F, Squizzato A, Gianni M, De Lodovici ML, Venco A, Paciaroni M, Crowther M, Ageno W. Safety of thrombolysis in cerebral venous thrombosis. A systematic review of the literature. Thromb Haemost. 2010 Nov 3;104(5):1055-62. Epub 2010 Sep 30.

Garcia D, Crowther MA, Ageno W. [Practical treatment of warfarin associated coagulation disorder]. Praxis (Bern 1994). 2010 Dec 15;99(25):1569-73.

DENBURG, J.Ellis AK, Ackerman SJ, Crawford L, Du J, Bedi R, Denburg JA. Cord blood molecular biomarkers of eosinophilopoiesis: kinetic analy-sis of GATA-1, MBP1 and IL-5Ra mRNA expression. Ped Allergy Immunol 21:640-8, 2010.

Bousquet J, Schünemann HJ, Zuberbier T, Bachert C, Baena-Cagnani CE, Bousquet PJ, et al. In collaboration with the WHO

Collaborating Center of Asthma and Rhinitis (Montpellier). Development and implementation of guidelines in allergic rhinitis – An ARIA-GA2LEN paper. Allergy. 2010;65:1212-21.

DEVEREAUX, P.J.Mathew A, Eliasziw M, Devereaux PJ, Merino JG, Barnett HJM, Garg AX, for the North American Symptomatic Carotid Endarterectomy Trial (NASCET) Collaborators. Carotid endarter-ectomy benefits patients with CKD and symptomatic high-grade stenosis. J Am Soc Nephrol. 2010;21:145-52.

McDonald SD, Han Z, Walsh M, Gerstein H, Devereaux PJ. Kidney disease after preeclampsia: A systematic review and meta-analy-ses. Am J Kidney Dis. 2010;55:1026-39.

Kavsak PA, Worster A, You JJ, Oremus M, Hill SA, Devereaux PJ, MacRae AR, Jaffe AS. Identification of myocardial injury in the emergency setting. Clin Biochem. 2010;43:538-44.

Farrokhyar F, Karanicolas PJ, Thoma A, Simunovic M, Bhandari M, Devereaux PJ, Anvari M, Adili A, Guyatt G. Randomized controlled trials of surgical interventions. Ann Surg. 2010;251:409-16.

Schulz KF, Altman DG, Moher D; CONSORT Group (Member Devereaux PJ). CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials. BMJ. 2010 Mar 23;340:c869; PLoS Med. 2010 Mar 24;7(3):e1000251.

Moher D, Hopewell S, Schulz KF, Montori V, Gøtzsche PC, Devereaux PJ, Elbourne D, Egger M, Altman DG. CONSORT 2010 Explanation and Elaboration: updated guidelines for reporting parallel group randomised trials. BMJ. 2010 Mar 23;340:c869; J Clin Epidemiol. 2010 Aug;63(8):e1-37. Epub 2010 Mar 25.

Pogue J, Thabane L, Devereaux PJ, Yusuf S. Testing for heteroge-neity among the components of a binary composite outcome in a clinical trial. BMC Med Res Methodol. 2010;10:49.

Cairns JA, Yusuf S, Cook RJ, Cox J, Dagenais GR, Devereaux PJ, McAlister FA, McCready T. CANadian Network and Centre for Trials INternationally (CANNeCTIN): A national network for Canadian-led trials in cardiovascular diseases and diabetes mel-litus. Can J Cardiol. 2010;26:353-8.

Simunovic N, Devereaux PJ, Sprague S, Guyatt GH, Schemitsch EH, deBeer J, Bhandari M. Effect of early surgery after hip fracture on mortality and complications: systematic review and meta-analy-sis. CMAJ. 2010;182:1609-16.

Hiralal R, Guyatt G, Bhandari M, Cook D, Berwanger O, deBeer J, Cina C, Buckley N, Villar JC, Montori V, Marcaccio M, Paul J, Whiteacre L, Devereaux PJ. A survey evaluating surgeons’ peri-operative usage of acetyl-salicylic acid (ASA) and their willingness to enroll their patients in a perioperative ASA randomized con-trolled trial. Clin Invest Med. 2010;33:E375-E383.

DIVAKARAMENON, S.Menon SM, Healey JS, Morillo CA. Epsilon waves during ven-tricular tachycardia in a case of arrhythmogenic right ventricular dysplasia. Circulation. 2010 Oct 26;122(17):1752-5.

Menon SM, Ribas CS, Hussein MH, Morillo CA.Case of long RP tachycardia responsive to adenosine: What is the mechanism? Heart Rhythm. Epub 2010 Sep 22.

Nery PB, Fernandes R, Nair GM, Sumner GL, Ribas CS, Menon SM, Wang X, Krahn AD, Morillo CA, Connolly SJ, Healey JS. Device-related infection among patients with pacemakers and implant-able defibrillators: incidence, risk factors, and consequences. J Cardiovasc Electrophysiol. 2010 Jul;21(7):786-90. Epub 2010 Jan 22.

Divakara Menon SM, Chemello D, Morillo CA. Sarcoidosis: yet another masquerader the cardiologist / electrophysiologist has to fight with. Indian Pacing Electrophysiol J. 2010 Dec 26;10(11):479-85.

for Canadian-led trials in cardiovascular diseases and diabetes mellitus. Can J Cardiol. 2010;26(7):353-8.

COOK, D.Heyland DK, Cook DJ, Rocker GM, Dodek PM, Kutsogiannis DJ, Skrobik Y, Jiang X, Day A, Cohen SR. Patient and Family Caregiver Satisfaction with End of Life Care in Canada: Defining High Priority Opportunities for Improvement. Can Med Assoc J. 2010;182(16);E747.

Heyland DK, Cook DJ, Rocker GM, Dodek PM, Kutsogiannis DJ, Skrobik Y, Jiang X, Day A, Cohen SR. The Development and Testing of a Questionnaire to Measure Patient and Family Satisfaction with End of Life Care: The Canadian Health Care Evaluation Project (CANHELP) Questionnaire. Palliative Medicine. 2010;24:682-95. Epub 2010 Jul 6.

Heyland DK, Heyland J, Dhaliwal R, Madden S, Cook DJ. Randomized Trials in Critical Care Nutrition: Look how far we’ve come! (and where do we go from here?) J Parent Ent Nutrition. 2010;34:697-706.

Lamontagne F, Briel M, Duffett M, Fox-Robichaud A, Cook DJ, Guyatt GH, Lesur O, Meade MO for the ACCADEMY. Systematic review of reviews of preclinical studies on therapeutic interven-tions for sepsis. Crit Care Med. 2010:38:2401-8.

Hiralal R, Guyatt G, Bhandari M, Cook D, Berwanger O, deBeer J, Cina C, Buckley N, Villar JC, Montori V, Marcaccio M, Paul J, Whiteacre L, Devereaux PJ. A survey evaluating surgeons’ periop-erative usage of acetyl-salicylic acid (ASA) and their willingness to enroll their patients in a perioperative ASA randomized controlled trial. Clinical Investigative Medicine. 2010;33:E375-E383.

Finfer S, Liu B, Taylor C, Bellomo R, Billot L, Cook D, Du B, McArthur C, Myburgh J (Writing Committee) for the SAFE TRIPS Investigators. Resusciation fluid us in critically ill adults: An inter-national cross-sectional study in 391 ICUs. Crit Care. 2010;14:R185.

Cook DJ, Donadini M. Pulmonary embolism in medical-surgical critically ill patients. Hematol Oncol Clinic N America. 2010;24:677-82.

Cook DJ, Crowther MA. Thromboprophylaxis in the intensive care unit: Focus on medical-surgical patients. Crit Care Med. 2010;38(2):S76-S82.

Cook DJ, Burns K, Finfer S, Kissoon N, Bhagwanjee S, Annane D, Sprung C, Fowler R, Latronico N, Marshall J for the International Forum for Acute Care Trialists (InFACT) Ethics Committee. Clinical Research Ethics For Critically Ill Patients: A Pandemic Proposal. Crit Care Med. 2010:38(4 Suppl):e138-42.

Briel M, Zhou Q, Meade M, Cook DJ, Mercat A, Brochard L, Brower RG, Lamontagne F, Talmor D, Bhatnagar N, Walter S, Stewart TE, Slutsky AS, Pullenayegum E, Guyatt GH. Higher versus lower positive end-expiratory pressure in patients with acute lung injury and cute respiratory distress syndrome: systematic review and individual patient data meta-analysis. JAMA. 2010;303(9):865-73.

Bassler D, Briel M, Montori VM, Melanie L, Glasziou P, Zhou Q, Heels-Andsdell D, Walter SD, Guyatt GH for the STOPIT-2 Study Group. Randomized trials stopped early for benefit exaggerate treatment effects: systematic review and meta-regression analy-sis. JAMA. 2010;303(12):1180-7.

CROWTHER, M.Garcia D, Libby E, Crowther MA. The new oral anticoagulants. Blood. 2010 Jan 7;115(1):15-20.

Dentali F, Crowther M. Antiphospholipid antibodies in critical ill-ness. Crit Care Med. 2010 Feb;38(2 Suppl): S51-6. Review.

Cook DJ, Crowther MA. Thromboprophylaxis in the intensive care unit: focus on medical-surgical patients. Crit Care Med. 2010 Feb;38(2Suppl): S76-82.

Paikin J, Crowther M. Use of the Delphi method to establish guide-lines for treatment of thrombosis. Thromb Res. Epub 2010 Jan 29.

Chan WS, Lee A, Spencer FA, Chunilal S, Crowther M, Wu W, Johnston M, Rodger M, Ginsberg JS. D-dimer testing in pregnant patients: toward determining the next ‘level’ in the diagnosis of deep vein thrombosis. J Throm Haemost. 2010 May;8(5):1004-11.

Crowther MA, Cook DJ, Albert M, Williamson D, Meade M, Granton J, Skrobik Y, Langevin S, Mehta S, Hebert P, Guyatt GH, Geerts W, Rabbat C, Douketis J, Zytaruk N, Sheppard J, Greinacher A, Warkentin TE; Canadian Critical Care Trials Group. The 4Ts scoring system for heparin-induced thrombocytopenia in medical-surgical intensive care unit patients. J Crit Care. 2010 Jun; 25(2): 287-93.

Crowther M. ACP Journal Club. Risk for postoperative venous throm-boembolism in women was increased for > or = 12 weeks and varied by type of surgery. Ann Intern Med. 2010 Mar 16;152(6):JC3-11.

Fry JL, Arnold DM, Clase CM, Crowther MA, Holbrook AM, Traore AN, Warkentin TE, Heddle NM. Transfusion premedication to prevent acute transfusion reactions: a retrospective obser-vational study to assess current practices. Transfusion. 2010 Aug;50(8):1722-30. Epub 2010 Mar 25.

Witt DM, Delate T, Clark NP, Martell C, Tran T, Crowther MA, Garcia DA, Ageno W, Hylek EM; WARPED Consortium. Twelve-month outcomes and predictors of very stable INR control in prevalent Warfarin users. J Thromb Haemost. 2010 Apr;8(4):744-9.

Garcia D, Crowther MA, Ageno W. Practical management of coag-ulopathy associated with Warfarin. BMJ. 2010 Apr 19;340:c1813.

Crowther M, Crowther MA. Intensity of Warfarin coagulation in the antiphospholipid syndrome. Curr Rheumatol Rep. 2010 Feb;12(1):64-9.

Paikin JS, Wright DS, Crowther MA, Mehta SR, Eikelboom JW. Triple antithrombotic therapy in patients with atrial fibrillation and coronary artery stents. Circulation. 2010 May 11;121(18):2067-70.

Crowther MA, Garcia D, Ageno W, Wang L, Witt DM, Clark NP, Blostein MD, Kahn SR, Schulman S, Kovacs M, Rodger MA, Wells P, Anderson D, Ginsberg J, Selby R, Siragusa S, Silingardi M, Dowd MD, Kearon C. Oral vitamin K effectively treats international nor-malized ratio (INR) values in excess of 10. Results of a prospective cohort study. Thromb Haemost. 2010 Jul 5;104(1):118-21.

Guyatt G, Akl EA, Hirsh J, Kearon C, Crowther M, Gutterman D, Lewis SZ, Nathanson I, Kaeschke R, Schunemann H. The vexing problem of guidelines and conflict of interest: a potential solution. Ann Intern Med. 2010 Jun 1;152(11):738-41.

Ghanny S, Crowther M. Management of deep vein thrombosis diagnosed during active labour. Thromb Res. Epub 2010 Oct 2.

Clark CA, Spitzer KA, Laskin CA, Crowther MR, Ginsberg JS. Heparin treatment in antiphospholipid syndrome with recurrent pregnancy loss. Obstet Gynecol. 2010 Oct;116(4):997-8; author reply 998.

Lepic K, Crowther M. New Anticoagulants for the Prevention of Thromboembolism. Curr Pharm Des. 2010;16(31):3472-4. Review.

Cuker A, Arepally G, Crowther MA, Rice L, Datko F, Hook K, Propert KJ, Kuter DJ, Ortel TL, Konkle BA, Cines DB. The HIT expert prob-ability (HEP) score: a novel pre-test probability model for hepa-rin-induced thrombocytopenia based on broad expert opinion. J Thromb Haemost. 2010 Dec;8(12):2642-50.

Ruiz-Irastorza G, Crowther M, Branch W, Khamashta MA. Antiphospholipid syndrome. Lancet. Epub 2010 Sep 6.

Dentali F, Crowther M. Venous thromboembolism, age and hospi-talisation: A potentially deadly combination. Thromb Haemost. 2010 Oct;104(4):655-6.

Cuker A, Raby A, Moffat KA, Flynn G, Crowther MA. Interlaboratory variation in heparin monitoring: Lessons from the Quality

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PUBLICATIONS

Pasquale G, Niemela K, Ajani AE, White HD, Chrolavicius S, Gao P, Fox KA, Yusuf S; on behalf of the CURRENT-OASIS 7 trial investiga-tors. Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomized factorial trial. Lancet. 2010;376(9748):1233-43.

FUTURA/OASIS- Trial Group (including Eikelboom JW). Low-dose vs standard-dose unfractionated heparin for percutaneous coronary intervention in acute coronary syndromes treated with fondaparinux: the FUTURA/OASIS-8 randomized trial. JAMA. 2010;304(12):1339-49.

Wallentin L, Yusuf S, Ezekowitz MD, Alings M, Flather M, Franzoso MG, Pais P, Dans A, Eikelboom JW, Oldgren J, Pogue J, Reilly PA, Yang S, Connolly SJ; RE-LY investigators. Efficacy and safety of dabigatran compared with warfarin at different levels of interna-tional normalised ratio control for stroke prevention in atrial fibril-lation: an analysis of the RE-LY trial. Lancet. 2010;376(9745):975-83.

VITATOPS Trial Study Group including Eikelboom JW. B vitamins in patients with recent transient ischemic attack or stroke in the VITAmins TO Prevent Stroke (VITATOPS) trial: a randomised, double-blind, parallel, placebo-controlled trial. Lancet Neurol. 2010;9(9):855-65.

Eikelboom JW, Emery J, Hankey GJ. The use of platelet function assays may help to determine appropriate antiplatelet treatment options in a patient with recurrent stroke on a baby aspirin. Stroke. 2010;41(10):2398-9.

Paikin JS, Eikelboom JW, Cairns JA, Hirsh J. New antithrombotic agents-insights from clinical trials. Nat Rev Cardiol. 2010;7(9):498-509.

Dahl OE, Quinlan DJ, Bergqvist D, Eikelboom JW. A critical appraisal of bleeding events reported in venous thromboembolism prevention trials of patients undergoing hip and knee arthroplasty. J Thromb Haemost. 2010;8(9):1966-75.

Karthikeyan G, Eikelboom JW. Apixaban in Acute Coronary Syndromes. Cardiovasc Ther. Epub 2010 Jun 11.

Schwalm JD, Ahmad M, Eikelboom JW, Natarajan MK. A national survey of Canadian practice patterns of warfarin after anterior wall myocardial infarction in the current era of dual antiplatelet therapy. Am J Cardiol. 2010;105(12):1844.

Sobieraj-Teague M, Eikelboom JW. Point-of-care testing for assessment of adequacy of oral antiplatelet therapy in patients with cardiovascular disease. Future Cardiol. 2010;6(3):289-99.

Karthikeyan G, Eikelboom JW. The CHADS2 score for stroke risk stratification in atrial fibrillation - friend or foe? Thromb Haemost. 2010;104(1):45-8.

Paikin JS, Wright DS, Crowther MA, Mehta SR, Eikelboom JW. Triple antithrombotic therapy in patients with atrial fibrillation and coronary artery stents. Circulation. 2010;121(18):2067-70.

Paikin J, Mehta S, Eikelboom JW. Role of triple antithrombotic therapy in patients with atrial fibrillation and coronary artery stents. Med J Aust. 2010;192(9):487-8.

Eikelboom JW, Cook R, Liu Y, Heddle N. Duration of Red Cell Storage Prior to Transfusion and In-hospital Mortality. Am Heart J. 2010;159(5):737-743.e1.

Karthikeyan G, Eikelboom JW, Hirsh J. Dabigatran: ready for prime time? Pol Arch Med Wewn. 2010;120(4):137-42.

Eikelboom JW, Weitz JI. New Anticoagulants. Circulation. 2010;121(13):1523-32.

Amlani S, Nadaraj T, Afzal R, Pal R, Eikelboom JW, Natarajan M. Mortality and Morbidity following a Major Bleed in a Registry Population with Acute ST Elevation Myocardial Infarction. J Thromb Thrombolysis. 2010;30(4):434-40.

Eikelboom JW, O’Donnell M, Yusuf S, Diaz R, Flaker G, Hart R, Hohnloser S, Joyner C, Lawrence J, Pais P, Pogue J, Synhorst D, Connolly SJ. Rationale and Design of AVERROES: Apixaban Versus Acetylsalicylic Acid to Prevent Stroke in Atrial Fibrillation Patients Who Have Failed or Are Unsuitable for Vitamin K Antagonist Treatment. Am Heart Journal. 2010;159(3):348-353.e1.

ROCKET AF Study Investigators (including Eikelboom JW). Rivaroxaban-once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and Embolism Trial in Atrial Fibrillation: rational and design of the ROCKET AF study. Am Heart J. 2010; 159(3):340-7.e1.

Gurbel PA, Bliden KP, Butler K, Antonino MJ, Wei C, Teng R, Rasmussen L, Storey RF, Nielsen T, Eikelboom JW, Sabe-Affaki G, Husted S, Kereiakes DJ, Henderson D, Patel DV, Tantry US. Response to ticagrelor in clopidogrel nonresponders and respond-ers and effect of switching therapies: the RESPOND study. Circulation. 2010;121(10):1188-99.

Hankey GJ, Eikelboom JW. Antithrombotic drugs for patients with ischaemic stroke and transient ischaemic attack to prevent recur-rent major vascular events. Lancet Neurol. 2010;9(3):273-84. Review.

Eikelboom JW, Weitz JI. Another oral thrombin inhibitor for stroke prevention in atrial fibrillation? Thromb Haemost. 2010 Jan;103(3):481-3.

Anderson J, Hirsh J, Yusuf S, Johnston M, Afzal R, Mehta S, Fox KA, Budaj, Eikelboom JW. Comparison of the Anticoagulant Intensities of Fondaparinux and Enoxaparin in the OASIS-5 Trial. J Thromb Haemost. 2010;8(2):243-9.

Schwalm JD, Ahmad M, Salehian O, Eikelboom JW, Natarajan MK. Warfarin after anterior myocardial infarction in current era of dual antiplatelet therapy: a randomized feasibility trial. J Thromb Thrombolysis. 2010 Aug;30(2):127-32.

Eikelboom JW, Zelenkofske SL, Rusconi CP. Coagulation factor IX as a target for treatment and prophylaxis of venous thromboembo-lism. Arterioscler Thromb Vasc Biol. 2010;30(3):382-7.

Chu SG, Becker RC, Berger PB, Bhatt DL, Eikelboom JW, Konkle B, Mohler ER, Reilly MP, Berger JS. Mean platelet volume as a predictor of cardiovascular risk: a systematic review and meta-analysis. J Thromb Haemost. 2010;8:148-56.

Sobieraj-Teague M, Eikelboom JW, Hirsh J. How can we reduce disagreement among guidelines for venous thromboembolism pre-vention? J Thromb Haemost. 2010 Apr;8(4):675-7.

Eikelboom JW, Wallentin L, Yusuf S, Ezekowitz MD, Reilly PA, Brueckmann M, Clemens A, Connolly SJ. Does dabigatran improve stroke-prevention in atrial fibrillation? J Thromb Haemost. Epub 2010 Feb 9.

FAN, J.Healey A, Sherbino J, Fan J, Mensour M, Upadhye S, Wasi P. A low-fidelity simulation curriculum addresses needs identified by faculty and improves the comfort level of senior internal medicine resident physicians with inhospital resuscitation. Crit Care Med. 2010 Sep;38(9):1899-903.

FORSYTHE, P.Forsythe P, Bienenstock J. Immunomodulation by commensal and probiotic bacteria. Immunol Invest. 2010;39(4-5):429-48.

Lyons A, O’Mahony D, O’Brien F, MacSharry J, Sheil B, Ceddia M, Russell WM, Forsythe P, Bienenstock J, Kiely B, Shanahan F, O’Mahony L. Bacterial strain-specific induction of Foxp3+ T regula-tory cells is protective in murine allergy models. Clin Exp Allergy. 2010;40(5):811-9.

Karimi K, Bienenstock J, Wang L, Forsythe P. The vagus nerve modu-lates CD4+ T cell activity. Brain Behav Immun. 2010;24(2):316-23.

Divakara Menon SM, Ribas CS, Ribas Meneclier CA, Morillo CA. Intermittent atrioventricular block: What is the mechanism? Heart Rhythm. Epub 2010 Nov 9.

Divakara Menon SM, Healey JS, El Bayomy M, Morillo CA. Entrainment of supraventricular tachycardia: What is the mecha-nism? Heart Rhythm. Epub 2010 Nov 9.

DOLOVICH, M.Yaghi A, Zaman A, Dolovich M. Primary human bronchial epithelial cells grown from explants. J Vis Exp. 2010 Mar 26;(37). pii:1789.

Scheuch G, Bennett W, Borgström L, Clark A, Dalby R, Dolovich M, Fleming J, Gehr P, Gonda I, O’Callaghan C, Taylor G, Newman S. Deposition, imaging, and clearance: what remains to be done? J Aerosol Med Pulm Drug Deliv. 2010 Dec;23 Suppl 2:S39-57.

Dolovich MB, Dhand R. Aerosol drug delivery: developments in device design and clinical use. Lancet. 2011 Mar 19;377(9770):1032-45. Epub 2010 Oct 29.

DORE, K.Dore KL, Kreuger S, Ladhani M, Rolfson D, Kurtz D, Kulasegaram K, Cullimore AJ, Norman GR, Eval KW, Bates S, Reiter HI. Reliability and acceptability of the MMI: A non-cognitive skills assessment for post-graduate admissions. Academic Medicine. 2010 Oct;85(10):S60-63.

DOUKETIS, J.Kaatz S, Douketis J, Zhou H, Gage BF, White RH. Risk of stroke after surgery in patients with and without chronic atrial fibrillation. J Thromb Haemost. 2010 May;8(5):884-90.

Pai M, Douketis J. Preventing venous thromboembolism in long-term care residents: Cautious advice based on limited data. Cleve Clin J Med. 2010 Feb;77(2):123-30.

Johnson SA, Stevens SM, Woller SC, Lake E, Donadini M, Cheng J, Labarere J, Douketis J. Risk of deep vein thrombosis following a single negative whole-leg compression ultrasound: a systematic review and meta-analysis. JAMA. 2010;303(5):438-45.

Prandoni P, Casiglia E, Piccioli A, Ghirarduzzi A, Pengo V, Gu C, Douketis J. The risk of cancer in patients with venous thromboem-bolism does not exceed that expected in the general population after the first 6 months. J Thromb Haemost. 2010;8(5):1126-7.

Crowther MA, Cook DJ, Albert M, Williamson D, Meade M, Granton J, Skrobik Y, Langevin S, Mehta S, Hebert P, Guyatt GH, Geerts W, Rabbat C, Douketis J, Zytaruk N, Sheppard J, Greinacher A, Warkentin TE; Canadian Critical Care Trials Group. The 4Ts scor-ing system for heparin-induced trombocitopenia in medical-surgi-cal intensive care unit patients. J Crit Care. 2010;25(2):287-93.

Lassen MR, Raskob GE, Gallus A, Pineo G, Chen D, Hornick P, ADVANCE-2 investigators. Apixaban versus enoxaparin for throm-boprophylaxis after knee replacement (ADVANCE-2): a randomized double-blind trial. Lancet. 2010;375:807-15.

Bohm M, Baumhakel M, Teo K, Sleight P, ONTARGET/TRANSCEND Erectile dysfunction substudy investigators, et al. Erectile dysfunc-tion predicts cardiovascular events in high-risk patients receiving telmisartan, ramipril, or both: The Ongoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial/Telmisartan Randomized Assessment Study in ACE iNtolerant subjects with cardiovascular disease (ONTARGET/TRANSCEND) Trials. Circulation. 2010;121(12):1439-46.

Ageno W, Dentali F, Squizzato A, Baglin T, Douketis J, Lansberg M, et al. Evidence and clinical judgement: Treatment of cerebral vein thrombosis. Thromb Haemost. 2010;103(6):1109-15.

Jamula E, Lloyd NS, Schwaim JD, Airaksinen KE, Douketis J. Safety of uninterrupted anticoagulation in patients requiring elec-

tive coronary angiography with or without percutaneous coronary intervention: A systematic review and meta-analysis. Chest. 2010;138(4):840-7.

Ueng J, Douketis JD. Prevention and treatment of hormone-associ-ated venous thromboembolism: a patient management approach. Hematol Oncol Clin North Am. 2010;24(4):683-94, vii-viii.

Baglin T, Douketis J, Tosetto A, Marcucci M, et al. Does the clinical presentation and extent of venous thrombosis predict likelihood and type of recurrence? A patient level meta-analysis. J Thromb Haemost. 2010;8(11):2436-42.

Douketis J. Pharmacologic properties of the new oral anticoagu-lants: A clinician-oriented review with a focus on perioperative management. Curr Pharm Des. 2010;16(31):3436-41.

Guerrouij M, Uppal CS, Alklabi A, Douketis J. The clinical impact of bleeding during oral anticoagulant therapy: Assessment of morbid-ity, mortality and post-bleed anticoagulant management. J Thromb Thrombolysis. Epub 2010 Dec 23.

Lassen MR, Gallus A, Raskob GE, Pineo G, Chen D, Ramirez LM; ADVANCE-3 Investigators. Apixaban versus enoxaparin for thrombophylaxis after hip replacement. N Engl J Med. 2010;Dec 23;363(26):2487-98.

Douketis J, Julian JA, Crowther MA, Kearon C, et al. The effect of prothrombotic blood abnormalities on risk of deep vein thrombosis in users of hormone replacement therapy: A prospective case-control study. Clin Appl Thromb Hemost. Epub 2010 Dec 15.

Stevens SM, Douketis J. Deep vein thrombosis prophylaxis in hos-pitalized medical patients: current recommendations, general rates of implementation, and initiatives for improvement. Clin Chest Med. 2010;31(4):675-89.

Douketis J, Tosetto A, Marcucci M, Baglin T, et al. Patient-level meta-analysis: effect of measurement timing, threshold, and patient age on ability of D-dimer testing to assess recurrence risk after unprovoked venous thromboembolism. Ann Intern Med. 2010;153(8):523-31.

EIKELBOOM, J.Sun JC, Teoh KH, Lamy A, Sheth T, Ellins ML, Jung H, Yusuf S, Anand S, Connolly S, Whitlock RP, Eikelboom JW. Randomized trial of aspirin and clopidogrel versus aspirin alone for the prevention of coronary artery bypass graft occlusion: the Preoperative Aspirin and Postoperative Antiplatelets in Coronary Artery Bypass Grafting study. Am Heart J. 2010;160(6):1178-84.

van Rees Vellinga TE, Peters RJ, Yusuf S, Afzal R, Chrolavicius S, O’Donnell M, Mehta SR, Pluta W, Sacha J, Eikelboom JW. Efficacy and safety of fondaparinux in patients with ST-segment eleva-tion myocardial infarction across the age spectrum. Results from the Organization for the Assessment of Strategies for Ischemic Syndromes 6 (OASIS-6) trial. Am Heart J. 2010;160(6):1049-55.

Nieuwlaat R, Barker L, Kim YK, Haynes RB, Eikelboom JW, Yusuf S, Connolly SJ. Underuse of evidence-based warfarin dosing methods for atrial fibrillation patients. Thromb Res. 2010 Apr;125(4):e128-31.

Pare G, Mehta SR, Yusuf S, Anand SS, Connolly SJ, Hirsh J, Simonsen K, Bhatt DL, Fox KA, Eikelboom JW. Effects of CYP2C19 genotype on outcomes of clopidogrel treatment. N Engl J Med. 2010;383(18):1704-14.

Mehta S, Bassand JP, Chrolavicius S, Diaz R, Eikelboom JW, Fox KA, Granger CB, Jolly S, Rupprecht HJ, Widimsky P, Afzal R, Pogue J, Yusuf S on behalf of CURRENT-OASIS 7 Investigators. Dose Comparisons of Clopidogrel and Aspirin in Acute Coronary Syndromes. NEJM. 2010;363(10):930-42.

Mehta SR, Tanguay JF, Eikelboom JW, Jolly SS, Joyner CD, Granger CB, Faxon DP, Ruppresht HJ, Budaj A, Avezum A, Widimsky P, Steg PG, Bassand JP, Montalescot G, Macaya C, Di

130

PUBLICATIONS

Meta-analysis. Am J Kidney Dis. 2010;55(6):1026-39.

Pullenayegum EM, Tarride JE, Xie F, Goeree R, Gerstein HC, O’Reilly D. Analysis of Health Utility Data When Some Subjects Attain the Upper Bound of 1: Are Tobit and CLAD Models Appropriate? Value Health. 2010;13(4):487-94.

ACCORD Study Group, Cushman WC, Evans GW, Byington RP, Goff DC Jr, Grimm RH Jr, Cutler JA, Simons-Morton DG, Basile JN, Corson MA, Probstfield JL, Katz L, Peterson KA, Friedewald WT, Buse JB, Bigger JT, Gerstein HC, Ismail-Beigi F. Effects of intensive blood-pressure control in type 2 diabetes mellitus. N Engl J Med. 2010;362(17):1575-85.

ACCORD Study Group, Ginsberg HN, Elam MB, Lovato LC, Crouse JR 3rd, Leiter LA, Linz P, Friedewald WT, Buse JB, Gerstein HC, Probstfield J, Grimm RH, Ismail-Beigi F, Bigger JT, Goff DC Jr, Cushman WC, Simons-Morton DG, Byington RP. Effects of com-bination lipid therapy in type 2 diabetes mellitus. N Engl J Med. 2010;362(17):1563-74.

Gerstein HC, Ratner RE, Cannon CP, Serruys PW, García-García HM, van Es GA, Kolatkar NS, Kravitz BG, Miller DM, Huang C, Fitzgerald PJ, Nesto RW; APPROACH Study Group. Effect of rosi-glitazone on progression of coronary atherosclerosis in patients with type 2 diabetes mellitus and coronary artery disease: the assessment on the prevention of progression by rosiglitazone on atherosclerosis in diabetes patients with cardiovascular history trial. Circulation. 2010;121:1176-87.

Mente A, Razak F, Blankenberg S, Vuksan V, Davis B, Miller R, Teo K, Gerstein H, Sharma AM, Yusuf S, Anand SS, for the SHARE and SHARE-AP investigators. Ethnic variation in adiponectin and leptin levels and their association with adiposity and insulin resistance. Diabetes Care. 2010;33:1629-34.

Gerstein HC. Does Insulin Therapy Promote, Reduce, or Have a Neutral Effect on Cancers? JAMA. 2010;303(5):446-7.

Miller ME, Bonds DE, Gerstein HC, Seaquist ER, Bergenstal RM, Calles-Escandon J, Childress RD, Craven TE, Cuddihy RM, Dailey G, Feinglos MN, Ismail-Beigi F, Largay JF, O’Connor PJ, Paul T, Savage PJ, Schubart UK, Sood A, Genuth S; ACCORD Investigators. The effects of baseline characteristics, glycaemia treatment approach, and glycated haemoglobin concentration on the risk of severe hypoglycaemia: post hoc epidemiological analy-sis of the ACCORD study. BMJ. 2010;8;340:b5444.

Bruin JE, Petrik JJ, Hyslop JR, Raha S, Tarnopolsky MA, Gerstein HC, Holloway AC. Rosiglitazone improves pancreatic mitochondrial function in an animal model of dysglycemia: role of the insulin-like growth factor axis. Endocrine. 2010;37(2):303-11.

Hanley AJ, Zinman B, Sheridan P, Yusuf S, Gerstein HC; for the DREAM Investigators. Effect of rosiglitazone and ramipril on {beta}-cell function in people with impaired glucose tolerance (IGT) or impaired fasting glucose (IFG): the DREAM Trial. Diabetes Care. 2010;33:608-18.

GINSBERG, J.Louis KM, Martineau J, Rodrigues I, Fournier M, Berbiche D, Blais N, Ginsberg J, Blais L, Montigny M, Perreault S, Vanier MC, Lalond L. Primary care practices and determinants of optimal anticoagu-lation management in a collaborative care model. Am Heart J. 2010;159:183-9.

Chan WS, Ramsay T, Ginsberg JS. Prediction rules must be devel-oped according to methodological guidelines. Ann Intern Med. 2010;152:263-4.

Chan WS, Spencer FA, Ginsberg JS. Anatomic distribution of deep vein thrombosis in pregnancy. CMAJ. 2010;182(7):657-60.

Crowther MA, Garcia D, Ageno W, Wang L, Witt DM, Clark NP, Blostein MD, Kahn SR, Schulman S, Kovacs M, Rodger MA, Wells P, Anderson D, Ginsberg J, Selby R, Siragusa S, Silingardi M,

Dowd MB, Kearon C. Oral vitamin K effectively treats INR values in excess of 10.0: Results of a prospective cohort study. Thromb Haemost. 2010;104(1):118-21.

Clark CA, Spitzer KA, Laskin CA, Crowther MR, Ginsberg JS. Heparin treatment in antiphospholipid syndrome with recurrent pregnancy loss. Obstet Gynecol. 2010;116:997-8.

Latella J, Desmarais S, Miron MJ, Roussin A, Joyal F, Kassis J, Solymoss S, Desjardins L, Ginsberg JS, Kahn SR. Relationship between D-dimer level, venous valvular reflux and development of the post-thrombotic syndrome after deep vein thrombosis. J Thromb Haemost. 2010;8:2169-75.

Chan WS, Lee A, Spencer FA, Chunilal S, Crowther M, Wu W, Johnston M, Rodger M, Ginsberg JS. D-Dimer Testing in Pregnant Patients: Towards Determining the Next “Level” in the Diagnosis of DVT. J Thromb Haemost. 2010;8:1004-11.

Douketis JD, Julian JA, Crowther MA, Kearon C, Bates SM, Barone M, Piovella F, Turpie AGG, Middeldorp S, van Nguyen P, Prandoni P, Anderson DR, Wells PS, Kovacs MJ, MacGillavry MR, Constantini L, Ginsberg JS. The effect of prothrombotic blood abnormalities on risk of deep vein thrombosis in users of hormone replacement therapy: A prospective case-control study. Clin Appl Thromb Hemost. Epub 2010 Dec 15.

GORDON, E.Beauchesne LM, Therrien J, Alvarez N, Bergin L, Burggraf G, Chetaille P, Gordon E, Kells CM, Kiess M, Mercier LA, Oechslin EN, Stein J, Tam JW, Taylor D, Williams A, Khairy P, Mackie AS, Silversides CK, Marelli AJ. Structure and process measures of quality of care in adult congenital heart disease patients: A pan-Canadian study. Int J Cardiol. Epub 2010 Dec 27.

GREENWALD, E.Quinton-Gladstone CL, Hotte SJ, Adachi JD, Greenwald E, Parasu N. Case report: Celiac disease masquerading as bone metastasis in a 29-year-old woman. J Clin Oncol. 2010 Nov 1;28(31):e623-5.

GUPTA, M.Gupta M, Honos GN, Velazquez EJ, Chung N, Oigman W, Maggioni AP. Evidence for the efficacy of ARBs across the cardiovascular continuum. Curr Med Res Opin. 2010 May;26(5):1203-18.

Grewal K, Leung YW, Safai P, Stewart DE, Anand S, Gupta M, Parsons C, & Grace SL. Improving access to cardiac rehabilitation among South Asian patients through innovative referral methods: A qualitative study. Rehabilitation Nursing. 2010;35(3):106-12.

Gupta M, Szmitko PE, Tsigoulis M, Braga M, Kajil M, Herjikaka S, Quan A, Teoh H, Verma S. Effects of ezetimibe add-on to statin therapy on adipokine production in patients with meta-bolic syndrome and stable vascular disease. J Cardiovascular Pharmacology. 2010 Sep;56(3):241-5.

Lovren F, Pan Y, Quan A, Singh KK, Shukla PC, Gupta M, Al-Omran M, Teoh H, Verma S. Adropin is a novel regulator of endothelial function. Circulation. 2010 Sept 14;122(11 Suppl):S185-92.

Lovren F, Pan Y, Quan A, Szmitko PE, Singh KK, Shukla PC, Gupta M, Chan L, Al-Omran M, Teoh H, Verma S. Adiponectin primes human monocytes into alternative anti-inflammatory M2 macro-phages. Am J Physiol Heart Circ Physiol. 2010 Sep;299(3):H656-63. Epub 2010 Jul 9.

Khan SN, Grace S, Oh P, Anand S, Stewart D, Wu G, Gupta M. A comparison of physical activity environments between south Asians and white Caucasians with coronary heart disease. Ethn Dis. 2010 Autumn 2010;20(4):390-5.

Forsythe P, Sudo N, Dinan T, Taylor VH, Bienenstock J. Mood and gut feelings. Brain Behav Immun. 2010;24(1):9-16.

FOX-ROBICHAUD, A.Lamontagne F, Briel M, Duffet M, Fox-Robichaud AE, Cook DJ, Guyatt G, Lesur O, Meade MO. Systematic review of reviews including animal studies addressing therapeutic interventions for sepsis. Crit Care Med. 2010 Dec;38(12):2401-8.

FREITAG, A.Aaron SD, Vandemheen KL, Ramotar K, Giesbrecht-Lewis T, Tullis E, Freitag A, Paterson N, Jackson M, Lougheed MD, Dowson C, Dumar V, Ferris W, Chan F, Doucette S, Fergusson D. Infection With Transmissible Strains of Pseudomonas aeruginosa and Clinical Outcomes in Adults With Cystic Fibrosis. JAMA. 2010 Nov 17;304(19):2145-53.

GAGNON, M.Lee L, Hillier LM, Stolee P, Heckman G, Gagnon M, McAiney CA, Harvey D. Enhancing Dementia Care: A Primary Care-Based Memory Clinic. J Amer Geri Soc. 2010;58:2197-204.

GANGJI, A.Al Helal B, Churchill DN, Su W, Gangji AS. Predictors of Hip Fracture in Hemodialysis Patients. Clinical Nephrology. 2010;73:88-93.

Lau JH, Gangji AS, Rabbat CG, Brimble KS. Impact of haemoglo-bin and erythropoietin dose changes on mortality: a secondary analysis of results from a randomized anemia management trial. Nephrol Dial Transplant. 2010 Dec;25(12):4002-9.

Su WS, Clase CM, Brimble KS, Margetts PJ, Wilkieson TJ, Gangji AS. Waist-to-Hip Ratio, Cardiovascular Outcomes, and Death in Peritoneal Dialysis Patients. Int J Nephrol. 2010 Jul 5;2010:831243.

Burger C, Clase CM, Gangji AS. Case Report: Drug Interaction between Tacrolimus and Amiodarone and QT prolongation. Transplantation. 2010 May 15;89(9):1166-7.

GANGULI, S.Hall GB, Kamath MV, Collins S, Ganguli S, Spaziani R, Miranda KL, Bayati A, Bienenstock J. Heightened Central Affective Response to Visceral Sensations of Pain and Discomfort in IBS. Neurogastroenterology & Motility. 2010;22(3)276-e80.

GAUVREAU, G.Dua B, Watson RM, Gauvreau GM, O’Byrne PM. Myeloid and plasmacytoid dendritic cells in induced sputum after allergen inhalation in subjects with asthma. J Allergy Clin Immunol. 2010 126(1):133-9.

Kelly MM, O’Connor TM, Leigh R, Otis J, Gwozd C, Gauvreau GM, Gauldie J, O’Byrne PM. Effects of budesonide and formoterol on allergen-induced airway responses, inflammation, and airway remodeling in asthma. J Allergy Clin Immunol. 2010;125(2):349-56.

GERSTEIN, H.Boyko EJ, Gerstein HC, Mohan V, Yusuf S, Sheridan P, Anand S, Shaw JE, DREAM trial investigators. Effects of ethnicity on diabe-tes incidence and prevention: results of the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) trial. Diabetic Medicine. 2010;27(11):1226-32.

ACCORD Study Group; ACCORD Eye Study Group, Chew EY, Ambrosius WT, Davis MD, Danis RP, Gangaputra S, Greven CM, Hubbard L, Esser BA, Lovato JF, Perdue LH, Goff DC Jr, Cushman

WC, Ginsberg HN, Elam MB, Genuth S, Gerstein HC, Schubart U, Fine LJ. Effects of medical therapies on retinopathy progression in type 2 diabetes. N Engl J Med. 2010;363(3):233-44.

Gerstein HC, Islam S, Anand S, Almahmeed W, Damasceno A, Dans A, Lang CC, Luna MA, McQueen M, Rangarajan S, Rosengren A, Wang X, Yusuf S. Dysglycaemia and the risk of acute myocardial infarction in multiple ethnic groups: an analysis of 15,780 patients from the INTERHEART study. Diabetologia. 2010;53(12):2509-17.

Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S; on behalf of the DREAM investigators. Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Diabetes Care. 2010;33(10):2250-3.

Zinman B, Harris SB, Neuman J, Gerstein HC, Retnakaran RR, Raboud J, Qi Y, Hanley AJ. Low-dose combination therapy with rosiglitazone and metformin to prevent type 2 diabetes mellitus (CANOE trial): a double-blind randomised controlled study. Lancet. 2010;376(9735):103-11.

Braga M, Casanova A, Teoh H, Dawson KC, Gerstein HC, Fitchett DH, Harris SB, Honos G, McFarlane PA, Steele A, Ur E, Yale JF, Langer A, Goodman SG, Leiter LA; Diabetes Registry to Improve Vascular Events (DRIVE) Investigators. Treatment gaps in the management of cardiovascular risk factors in patients with type 2 diabetes in Canada. Can J Cardiol. 2010;26(6):297-302.

Mente A, Yusuf S, Islam S, McQueen MJ, Tanomsup S, Onen CL, Rangarajan S, Gerstein HC, Anand SS; INTERHEART Investigators. Metabolic syndrome and risk of acute myocardial infarction a case-control study of 26,903 subjects from 52 countries. J Am Coll Cardiol. 2010 May 25;55(21):2390-8.

Sherifali D, Nerenberg K, Pullenayegum E, Cheng JE, Gerstein HC. The Effect of Oral Antidiabetic Agents on Glycated Hemoglobin Levels: A Systematic Review and Meta-Analysis. Diabetes Care. 2010;33:1859-64.

de Koning L, Gerstein HC, Bosch J, Diaz R, Mohan V, Dagenais G, Yusuf S, Anand SS; EpiDREAM Investigators. Anthropometric measures and glucose levels in a large multi-ethnic cohort of individuals at risk of developing type 2 diabetes. Diabetologia. 2010 Jul;53(7):1322-30.

Pop-Busui R, Evans GW, Gerstein HC, Fonseca V, Fleg JL, Hoogwerf BJ, Genuth S, Grimm RH, Corson MA, Prineas R; the ACCORD Study Group. Effects of Cardiac Autonomic Dysfunction on Mortality Risk in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial. Diabetes Care. 2010;33:1578-84.

Kayaniyil S, Vieth R, Retnakaran R, Knight JA, Qi Y, Gerstein HC, Perkins B, Harris SB, Zinman B, Hanley AJ. Association of Vitamin D with Insulin Resistance and Beta-Cell Dysfunction in Subjects at Risk for Type 2 Diabetes. Diabetes Care. 2010;33:1379-81.

Ambrosius WT, Danis RP, Goff DC Jr, Greven CM, Gerstein HC, Cohen RM, Riddle MC, Miller ME, Buse JB, Bonds DE, Peterson KA, Rosenberg YD, Perdue LH, Esser BA, Seaquist LA, Felicetta JV, Chew EY; ACCORD Study Group. Lack of association between thia-zolidinediones and macular edema in type 2 diabetes: the ACCORD eye substudy. Arch Ophthalmol. 2010;128:312-8.

Swinnen SG, Dain MP, Aronson R, Davies M, Gerstein HC, Pfeiffer AF, Snoek FJ, Devries JH, Hoekstra JB, Holleman F. A 24-week, randomized, treat-to-target trial comparing initiation of insulin glargine once-daily with insulin detemir twice-daily in patients with type 2 diabetes inadequately controlled on oral glucose-lowering drugs. Diabetes Care. 2010;33:1176-8.

Bruin JE, Gerstein HC, Holloway AC. Long-term consequences of fetal and neonatal nicotine exposure: a critical review. Toxicol Sci. 2010;116(2):364-74.

McDonald SD, Han Z, Walsh MW, Gerstein HC, Devereaux PJ. Kidney Disease After Preeclampsia: A Systematic Review and

132

PUBLICATIONS

McKibbon KA, Lokker C, Wilczynski NL, Ciliska D, Dobbins M, Davis DA, Haynes RB, Straus SE. A cross-sectional study of the number and frequency of terms used to refer to knowledge trans-lation in a body of health literature in 2006: a Tower of Babel? Implementation Sci. 2010;5:16.

Schulz KF, Altman D, Moher D for the CONSORT Group* CONSORT 2010 Statement: Updated guidelines for reporting parallel group randomized trials. Ann Intern Med. 2010;152:1-11.

Iansavichus AV, Haynes RB, Shariff SZ, Weir M, Wilczynski NL, McKibbon KA, Rehman F, Garg A. Optimal search filters for renal information in EMBASE. Am J Kidney Dis. 2010 Jul;56(1):14-22. Epub 2010 Mar 15.

Shariff S, Cuerden M, Haynes B, McKibbon A, Wilczynski N, Iansavichus A, Speechley M, Thind A, Garg A. Evaluating the impact of MEDLINE filters on evidence retrieval: study protocol. Implementation Science. 2010;5:58.

Lokker C, McKibbon KA, Wilczynski N, Haynes RB, Ciliska D, Dobbins M, Davis D, Straus S. Finding knowledge translation arti-cles in CINAHL. Stud Health Technol Inform. 2010;160(Pt 2):1179-83.

Wilczynski NL, Haynes RB. Optimal search filters for detecting quality improvement studies in Medline. Qual Safety Hlth Care. 2010 Dec;19(6):e31. Epub 2010 Jul 29.

Lavis JN, Wilson MG, Grimshaw JM, Haynes RB, Ouimet M, Raina P, Gruen R, Graham I. Supporting the use of health technology assessments in policymaking about health systems. Internat J Technol Assess Health Care. 2010; 26(4):405–14.

HEALEY, J.Lee DS, Krahn AD, Healey JS, Birnie D, Crystal E, Dorian P, Simpson CS, Khaykin Y, Cameron D, Janmohammed A, Yee R, Chen Z, Hardy J, Tu JV. Predictors of complications after implantable cardioverter defibrillator implantation for primary or secondary prevention. J Am Coll Cardiol. 2010;55(8):774-82.

Healey JS, Birnie DH, Krahn AD, Crystal E, Simpson CS, Dorian P, Chen Z, Cameron D, Verma A, Connolly SJ, Morillo CA, Gula L, Lockwood E, Nair GM, Tu JV. Defibrillation testing at the time of ICD implantation: An analysis from the Ontario ICD Registry. J Cardiovasc Electrophysiol. Epub 2010 Jul 19.

Nery P, Fernandes R, Nair G, Sumner G, Ribas C, Divakaramenon S, Wang X, Krahn A, Morillo CA, Connolly SJ, Healey JS. Device-related infection among patients with pacemakers and implant-able defibrillators: Incidence, risk factors and consequences. J Cardiovasc Electrophysiol. 2010 Jul;21(7):786-90. Epub 2010 Jan 22.

Parkash R, Crystal E, Bashir J, Simpson C, Birnie D, Sterns L, Exner D, Thibault B, Connors S, Healey JS, Champagne J, Cameron D, Mangat I, Verma A, Wolfe K, Essebag V, Kus T, Ayala-Paredes F, Davies T, Sanatani S, Gow R, Coutu B, Sivakumaran S, Stephenson E, Krahn A. Complications associated with revision of Sprint Fidelis leads: Report from the CHRS Device Advisory Committee. Circulation. 2010;121(22):2384-7.

Healey JS, Nair GM, Connolly SJ, Morillo CA. A Rare Cause of Implantable Cardioverter-Defibrillator Failure: Short-Circuiting via an Un-Used Pace-Sense Lead. Heart Rhythm. Epub 2010 Jul 20.

Divakaramenon S, Healey JS, Morillo CA. Epsilon waves during ventricular tachycardia in a case of arrhythmogenic right ventricu-lar dysplasia (ARVD). Circulation. 2010;122(17):1752-5.

Armaganijan L, Nair GM, Healey JS, Morillo CA. Falha de sensi-bilidade do marcapasso resultando em fenomeno “R sobre T” e fibrilacao ventricular. Revista Iberoamericana de Arritmologia. 2010;1(2):157-8.

Armaganijan L, Nair GM, Healey JS, Morillo CA. Choque inapropri-ado liberado por CDI: qual o mecanismo? Revista Iberoamericana de Arritmologia. 2010;1(2):159-61.

Tang AS, Wells GA, Talajic M, Arnold MO, Sheldon R, Connolly S, Hohnloser SH, Nichol G, Birnie DH, Sapp JL, Ree Y, Healey JS, Rouleau JL and the Resynchronization-Defibrillation for Ambulatory Heart Failure Trial Investigators. Cardiac-Resynchronization Therapy for Mild-to-Moderate Heart Failure. N Engl J Med. 2010;263(25):2385-95.

Divakaramenon S, Healey JS, El-Bayomy M, Morillo CA. Entrainment of supra-ventricular tachycardia. What is the mecha-nism of tachycardia? Heart Rhythm. 2010;8(11):1809-11.

Divakaramenon SM, Sumner GL, Ribas CS, Healey JS, Nair GM, Connolly SJ, Morillo CA. Contralateral pneumothorax in left-sided CRT device implantation. Indian Pacing and Electrophysiology. 2010;11(1):16-9.

Healey A, Sherbino J, Fan J, Upadhye S et al. A low-fidelity simula-tion curriculum addresses needs identified by faculty and improves the comfort level of senior internal medicine resident physicians with inhospital resuscitation. Crit Care Med. 2010;(38)9:1899-903.

HEDDLE, N.Arnold DM, Nazi I, Santos A, Chan H, Heddle NM, Warkentin TE, Kelton JG. Combination immunosuppressant therapy for patients with chronic refractory immune thrombocytopenic purpura. Blood. 2010 Jan 7;115(1):29-31.

Lange J, Selleng K, Heddle NM, Traore A, Greinacher A. Coomb’s crossmatch after negative antibody screening – a retrospective observational study comparing the test tube and the microcolumn technology. Vox Sang. 2010 Apr;98(3p1):e269-75.

Eikelboom JW, Cook RJ, Liu Y, Heddle NM. Duration of red cell storage before transfusion and in-hospital mortality. American Heart Journal. 2010 May;159(5):737-43.e1.

Heddle NM. The randomized controlled trial: In celebration of TRANSFUSION’S 50th. Transfusion. 2010 Jun;50(6):1173-8.

Arnold DM, Crowther MA, Meyer RM, Carruthers J, DiTomasso J, Heddle NM, McLeod A, Kelton JG. Misleading hepatitis B test results due to intravenous immunoglobulin administration: Implications for a clinical trial of rituximab in immune thrombocyto-penia. Transfusion. 2010 Dec;50(12):2577-81.

Reikvam H, Prowse C, Roddie H, Heddle NM, Hervig T for the BEST Collaborative. A pilot study of the possibility and the feasibility of haemoglobin dosing with red blood cells transfusion. Vox Sang. 2010 Jul 1;99(1):71-6.

Pavenski K, Warkentin TE, Shen H, Liu Y, Heddle NM. Posttransfusion platelet count increments after ABO-compat-ible versus ABO-incompatible platelet transfusions in noncancer patients: An observational study. Transfusion. 2010 Jul;50(7):1552-60.

Fry JL, Arnold DM, Clase CM, Crowther MA, Holbrook AM, Traore AN, Warkentin TE, Heddle NM. Transfusion premedication to prevent acute transfusion reactions: A retrospective obser-vational study to assess current practices. Transfusion. 2010 Aug;50(8):1722-30.

HOLBROOK, A.Fry J, Arnold D, Clase C, Crowther M, Holbrook A, Traore A, Warkentin T, Heddle N. Transfusion Premedication to Prevent Acute Transfusion Reactions: A Retrospective Observational Study to Assess Current Practices. Transfusion. 2010;50:1722-30.

Wong K, Yu S, Holbrook A. A systematic Review of Medication Safety Outcomes Related to Drug Interaction Software. J Popul Ther Clin Pharmacol. 2010;17(2):e243-e255.

Arkinson J, Holbrook A, Wiercioch W. Public Perceptions of Physician-Pharmaceutical Industry Interactions: A Systematic Review. Healthcare Policy. 2010;5(4):69-89.

GUYATT, G.Turner D, Schünemann HJ, Griffith LE, Beaton De, Griffiths AM, Critch JN, Guyatt GH. The minimal detectable change cannot reli-ably replace the minimal important difference. J Clin Epidemiol. 2010 Jan;63(1):28-36.

Ford AC, Guyatt GH, Talley NJ, Moayyedi P. Errors in the Conduct of Systematic Reviews of Pharmacological Interventions for Irritable Bowel Syndrome. Am J Gastroenterol. 2010 Feb;105(2):280-8.

Crowther MA, Cook DJ, Albert M, Williamson D, Meade M, Granton J, Skrobik Y, Langevin S, Mehta S, Hebert P, Guyatt GH, Geerts W, Rabbat C, Douketis J, Zytaruk N, Sheppard J, Greinacher A, Warkentin TE; For the Canadian Critical Care Trials Group. The 4Ts scoring system for heparin-induced thrombocyto-penia in medical-surgical intensive care unit patients. J Crit Care. 2010 Jun;25(2):287-93. Epub 2010 Feb 10.

Souza RF, Leles CR, Guyatt GH, Pontes CB, Della Vecchia MP, Neves FD. Exploratory factor analysis of the Brizilian OHIP for edentulous subjects. J Oral Rehabil. 2010 Mar;37(3):202-8.

Farrokhyar F, Karanicolas PJ, Thoma A, Simunovic M, Bhandari M, Devereaux PJ, Anvari M, Adili A, Guyatt G. Randomized controlled trials of surgical interventions. Ann Surg. 2010 Mar;251(3):409-16.

Briel M, Meade M, Mercat A, Brower RG, Talmor D, Walter SD, Slutsky AS, Pullenayegum E, Zhou Q, Cook D, Brochard L, Richard JC, Lamontagne F, Bhatnagar N, Stewart TE, Guyatt G. Higher vs lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory disease syndrome: systematic review and meta-analysis. JAMA. 2010 Mar 3;303(9):865-73.

Schunemann HJ, Sperati F, Barba M, Santesso N, Melegari C, Akl EA, Guyatt G, Muti P. An instrument to assess quality of life in rela-tionto nutrition: item generation, item reduction and initial valida-tion. Health Qual Life Outcomes. 2010 Mar 11;8:26.

Bassler D, Briel M, Montori VM, Lane M, Glasziou P, Zhou Q, Heels-Ansdell D, Walter SD, Guyatt GH; STOPIT-2 Study Group, Flynn DN, Elamin MB, Murad MH, Abu Elnour NO, Lampropulos JF, Sood A, Mullan RJ, Erwin PJ, Bankhead CR, Perera R, Ruiz Culebro C, You JJ, Mulla SM, Kaur J, Nerenberg KA, Schünemann H, Cook DJ, Lutz K, Ribic CM, Vale N, Malaga G, Akl EA, Ferreira-Gonzalez I, Alonso-Coello P, Urrutia G, Kunz R, Bucher HC, Nordmann AJ, Raatz H, da Silva SA, Tuche F, Strahm B, Djulbegovic B, Adhikari NK, Mills EJ, Gwadry-Sridhar F, Kirpalani H, Soares HP, Karanicolas PJ, Burns KE, Vandvik PO, Coto-Yglesias F, Chrispim PP, Ramsay T. Stopping randomized trials early for benefit and esti-mation of treatment effects: systematic review and meta-regres-sion analysis. JAMA. 2010 Mar 24;303(12):1180-7.

Sun X, Briel M, Walter SD, Guyatt GH. Is a subgroup effect believ-able? Updating criteria to evaluate the credibility of subgroup analyses. BMJ. 2010 Mar 30;340;c117.

Dahm P, Gilbert SM, Zlotecki RA, Guyatt GH. How to use an article about prognosis. J Urol. 2010 Apr;183(4):1303-8.

Turner D, Griffiths AM, Mack D, Otley AR, Seow CH, Steinhart AH, Silverberg MS, Hyams J, Guyatt GH. Assessing disease activity in ulcerative colitis: patients or their physicians? Inflamm Bowel Dis. 2010 Apr;16(4):651-6.

Scott IA, Guyatt GH. Cautionary tales in the interpretation of clini-cal studies involving older persons. Arch Intern Med. 2010 Apr 12;170(7):587-95.

Hill G, Goldstein RS, Guyatt GH, Blouin M, Tan WC, Davis LL, Heels-Ansdell DM, Erak M, Bragaglia PJ, Tamari IE, Hodder R, Stanbrook MB. Prevalence and underdiagnosis of chronic obstructive pulmo-nary disease among patients at risk in primary care. CMAJ. 2010 Apr 20;182(7):673-8.

Spragg RG, Bernard GR, Checkley W, Curtis JR, Gajic O, Guyatt G, Hall J, Israel E, Jain M, Needham DM, Randolph AG, Rubenfeld GD, Schoenfeld D, Thompson BT, Ware LB, Young D, Harabin AL.

Beyond mortality: future clinical research in actue lung injury. Am J Respir Crit Care Med. 2010 May 15;181(10):1121-7.

Guyatt G, Akl EA, Hirsh J, Kearon C, Crowther M, Gutterman D, Lewis SZ, Nathanson I, Jaeschke R, Schünemann H. The vexing problem of guidelines and conflict of interest: a potential solution. Ann Intern Med. 2010 Jun 1;152(11):738-41.

Johnston BC, Thorlund K, Schünemann HJ, Xie F, Murad MH, Montori VM, Guyatt GH. Improving he interpretation of quality of life evidence in meta-analysis: the application of minimal important difference units. Health Qual Life Outcomes. 2010 Oct 11;8:116.

Simunovic N, Devereaux PJ, Sprague S, Guyatt GH, Schemitsch E, Debeer J, Bhandari M. Effect of early surgery after hip fracture on mortality and complications: systematic review and meta-analysis. CMAJ. 2010 Oct 19:182(15):1609-16.

Mella JM, Perret MC, Manzotti M, Catalano HN, Guyatt G. Efficacy and safety of finasteride therapy for androgenetic alopecia: a sys-tematic review. Arch Dermatol. 2010 Oct;146(10):1141-50.

Fan E, Laupacis A, Pornovost PJ, Guyatt GH, Needham, DM. How to use an article about quality improvement. JAMA. 2010 Nov 24;304(20):2279-87.

Lamontagne F, Briel M, Duffett M, Fox-Robichaud A, Cook DJ, Guyatt G, Lesur O, Meade MO. Systematic review of reviews including animal studies addressing therapeutic interventions for sespsis. Crit Care Med. 2010 Dec;38(12):2401-8.

Hiralal R, Guyatt G, Bhandari M, Cook D, Berwanger O, De Beer J, Cina C, Buckley N, Villar JC, Montori V, Marcaccio M, Paul J, Whiteacre L, Devereaux PJ. A survey evaluating surgeons’ peri-operative usage of acetyl-salicylic acis (ASA) and their willingness to enroll their patients in a perioperative ASA randomized con-trolled trial. Clin Invest Med. 2010 Dec 1;33(6):E375-83.

HALDER, S.Halder SLS, Macfarlane GJ, Thompson DG, O’Brien SJ, Musleh M, McBeth J. Predictors of persistent gastrointestinal symptoms among new presenters to primary care. Eur J Gastroenterol Hepatol. 2010 Mar;22(3):296-305.

Chang JY, Locke GR, McNally MA, Halder SLS, Schleck CD, Zinsmeister AR, Talley NJ. Impact of functional gastrointestinal disorders on survival in the community: Chronic constipation is associated with poorer survival in a United States population. Am J Gastroenterol. 2010;105(4):822-32.

HARGREAVE, F.Chakir J, Loubaki L, Laviolette M, Milot J, Biardel S, Jayaram L, Pizzichini M, Pizzichini E, Hargreave FE, Nair P, Boulet LP. Monitoring sputum eosinophils in mucosal inflammation and remodelling: a pilot study. Eur Respir J. 2010;351:48-53.

Hassan NM, Hargreave FE, Nair P. Airway responsiveness to indi-rect challenges in COPD. COPD. 2010;7:133-40.

Nair P, Hargreave FE. Measuring bronchitis in airway diseases: clinical implementation and application. Chest. 2010;138:38S–43S.

Nair P, O’ Byrne PM, Hargreave FE, Kjarsgaard M, Armstrong S, Efthimiadis A. Nitric oxide in exhaled breath is poorly correlated to sputum eosinophils in patients with prednisone-dependent asthma. J Allergy Clin Immunol. 2010;126(2):404-6.

HAYNES, B.Haynes RB, Wilczynski NL for the Computerized Clinical Decision Support System (CCDSS) Systematic Review Team. Effects of comput-erized clinical decision support systems on practitioner performance and patient outcomes: Methods of a decision-maker-researcher part-nership systematic review. Implementation Sci. 2010;5:12.

134

PUBLICATIONS

Chow CK, Jolly SS, Rao-Melacini P, Fox KA, Anand SS, Yusuf S. Association of diet, exercise and smoking modification with risk of early cardiovascular events after acute coronary syndromes. Circulation. Feb 2010;121(6):750-8.

KAMATH, M.Hall GB, Kamath MV, Collins S, Ganguli S, Spaziani R, Miranda KL, Bayati A, Bienenstock J. Heightened central affective response to visceral sensations of pain and discomfort in IBS. Neurogastroenterol Motil. 2010 Mar;22(3):276-e80. Epub 2009 Dec 11.

Lodder A, Kamath MV, Upton AR, Armstrong D. Evaluation of the efficacy and performance of medical implants: a review. J Long Term Eff Med Implants. 2010;20(3):173-85.

Kamath MV, Thomson MS, Gaitonde S, Upton A. Longer-term effects of implanted vagal nerve stimulation. J Long Term Eff Med Implants. 2010;20(3):251-67.

Nolan RP, Floras JS, Harvey PJ, Kamath MV, Picton PE, Chessex C, Hiscock N, Powell J, Catt M, Hendrickx H, Talbot D, Chen MH. Behavioral neurocardiac training in hypertension: a randomized, controlled trial. Hypertension. 2010 Apr;55(4):1033-9. Epub 2010 Mar 1.

KEAN, W.Zhang T, Adatia A, Zarin W, Moitri M, Vijenthira A, Chu R, Thabane L, Kean W. The efficacy of botulinum toxin type A in managing chronic musculoskeletal pain: a systematic review and meta analysis. Inflammopharmacology. 2011 Feb;19(1):21-34. Epub 2010 Nov 13.

KEARON, C.Guyatt G, Akl EA, Hirsh J, Kearon C, Crowther M, Gutterman D, Lewis SZ, Nathanson I, Jaeschke R, Schünemann H. The vexing problem of guidelines and conflict of interest: A potential Solution. Ann Intern Med. 2010;152:738-41.

Nieto JA, Solano R, Ruiz-Ribo MD, Ruiz-Gimenez N, Prandoni P, Kearon C, Monreal M for The RIETE Investigators. Fatal bleeding in patients receiving anticoagulant therapy for venous thrombo-embolism: findings from the RIETE registry. J Thrombo Haemost. 2010;8:1216-22.

Linkins L, O’Donnell M, Julian JA, Kearon C. Intracranial and fatal bleeding according to indication for long-term oral anticoagulant therapy. J Thrombo Haemost. 2010;8:2201-7.

Iorio A, Kearon C, Filippucci E, Marcucci M, Macura A, Pengo V, Agnelli G, Palareti G. Risk of recurrence after a first episode of symptomatic venous thromboembolism provoked by a transient risk factor. A systematic review of the literature. Arch Intern Med. 2010;170(19):1710-6.

Kearon C. Long-term anticoagulation for venous thromboembolism: Duration of treatment and management of warfarin therapy. Clin Chest Med. 2010;31:719-30.

Kearon C, O’Donnell M. Should patients with stroke wear compres-sion stockings to prevent venous thromboembolism? Ann Intern Med. 2010;153:610-1.

Kearon C, Iorio A, Palareti G, on behalf of the Subcommittee on Control of Anticoagulation of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Risk of recurrent venous thromboembolism after stopping treatment in cohort studies: recommendation for accept-able rates and standardized reporting. J Thromb Haemost. 2010;8:2313-5.

Couturaud F, Kearon C. Predictors of thrombosis in relatives of patients with venous thromboembolism. Curr Opin Pulm Med. 2010;16:453-8.

Arnold DM, Anderson J, Kearon C. [Preoperative evaluation of bleeding and thromboembolism risk]. Praxis (Bern 1994). 2010;99:609-12.

Crowther MA, Garcia D, Ageno W, Wang L, Witt DM, Clark NP, Blostein MD, Kahn SR, Schulman S, Kovacs M, Rodger MA, Wells P, Anderson D, Ginsberg J, Selby R, Siragusa S, Silingardi M. Dowd MBB, Kearon C. Oral vitamin K effectively treats international nor-malised ratio (INR) values in excess of 10. Results of a prospective cohort study. Thromb Haemost. 2010;104:118-21.

KEITH, P.Bousquet J, Bachert C, Canonica GW, Mullol J, Van Cauwenberge P, Jensen CB, Fokkens WJ, Ring J, Keith P, Gopalan G, Lorber R, Zuberbier T; ACCEPT-2 Study Group. Efficacy of desloratadine in persistent allergic rhinitis - a GA²LEN study. Int Arch Allergy Immunol. 2010;153(4):395-402. Epub 2010 Jun 18.

Fiocchi A, Brozek J, Schünemann H, Bahna SL, von Berg A, Beyer K, Bozzola M, Bradsher J, Compalati E, Ebisawa M, Guzmán MA, Li H, Heine RG, Keith P, Lack G, Landi M, Martelli A, Rancé F, Sampson H, Stein A, Terracciano L, Vieths S; World Allergy Organization (WAO) Special Committee on Food Allergy. World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow’s Milk Allergy (DRACMA) Guidelines. Pediatr Allergy Immunol. 2010 Jul;21 Suppl 21:1-125.

Bowen T, Cicardi M, Farkas H, Bork K, Longhurst HJ, Zuraw B, et al. 2010 International consensus algorithm for the diagnosis, ther-apy and management of hereditary angioedema. Allergy Asthma Clin Immunol. 2010 Jul 28;6(1):24.

Cicardi M, Banerji A, Bracho F, Malbrán A, Rosenkranz B, Riedl M, et al. Icatibant, a new bradykinin-receptor antagonist, in hereditary angioedema. N Engl J Med. 2010 Aug 5;363(6):532-41. Erratum in: N Engl J Med. 2010 Oct 7;363(15):1486.

Bousquet J, Schünemann HJ, Zuberbier T, Bachert C, Baena-Cagnani CE, Bousquet PJ, et al; In collaboration with the WHO Collaborating Center of Asthma and Rhinitis (Montpellier). Development and implementation of guidelines in allergic rhinitis – an ARIA-GA2LEN paper. Allergy. 2010 Oct;65(10):1212-21.

Calverley PM, Rabe KF, Goehring UM, Kristiansen S, Fabbri LM, Martinez FJ; M2-124 and M2-125 study groups. Roflumilast in symptomatic chronic obstructive pulmonary disease: two ran-domised clinical trials. Lancet. 2009 Aug 29;374(9691):685-94. Erratum in: Lancet. 2010 Oct 2;376(9747):1146.

KELTON, J.Arnold DM, Nazi I, Santos A, Chan H, Heddle NM, Warkentin TE, Kelton JG. Combination immunosuppressant therapy for patients with chronic refractory immune thrombocytopenic purpura. Blood. 2010;115(1):29-31.

Warkentin TE, Sheppard JI, Moore JC, Kelton JG. Use of well-characterized sera for assessment of new diagnostic enzyme-immunoassays for diagnosis of heparin-induced thrombocytope-nia. J Thromb Haemost. 2010;8(1):216-8.

Arnold DM, Crowther MA, Meyer RM, Carruthers J, Ditomasso J, Heddle NM, McLeod A, Kelton JG. Misleading hepatitis B test results due to intravenous immunoglobulin administration: implica-tions for a clinical trial of rituximab in immune thrombocytopenia. Transfusion. 2010;50(12):2577-81.

KHALIDI, N.Jewett LR, Hudson M, Haythornthwaite JA, Heinberg L, Wigley FM, Baron M, Thombs BD; Canadian Scleroderma Research Group. Development and validation of the brief-satisfaction with appear-ance scale for systemic sclerosis. Arthritis Care Res (Hoboken). 2010 Dec;62(12):1779-86. Epub 2010 Jul 27.

Haynes B, Wilczynski N, and the Computerized Clinical Decision Support System (CCDSS) Systematic Review Team. Effects of computerized clinical decision support systems on practitioner performance and patient outcomes: Methods of a decision-maker-researcher partnership systematic review. Implement Sci. 2010;5(1):12.

HUIZINGA, J.Zhang Y, Carmichael SA, Wang XY, Huizinga JD & Paterson WG. Neurotransmission in Lower Esophageal Sphincter of W/Wv Mutant Mice. Am J Physiol Gastrointest Liver Physiol. 2010 Jan;298(1):G14-24. Epub 2009 Oct 22.

Zhu Y, Parsons SP & Huizinga JD. Measurement of intracellular chloride ion concentration in ICC in situ and explant culture. Neurogastroenterol Motil. 2010 Jun;22(6):704-9.

Huizinga JD, Lammers WJ, Mikkelsen HB, Zhu Y, Wang XY. Toward a concept of stretch coupling in smooth muscle: a thesis by Lars Thuneberg on contractile activity in neonatal interstitial cells of Cajal. Anat Rec (Hoboken). 2010 Sep;293(9):1543-52.

Parsons SP and Huizinga JD. Transient Outward Potassium Current in ICC. Am J Physiol Gastrointest Liver Physiol. 2010 Mar;298(3):G456-66.

Wang B, Mao YK, Diorio C, Wang L, Huizinga JD, Bienenstock J, Kunze W. Lactobaccillus reuteri ingestion and IK (Ca) channel blockade have similar effects on rat colon motility and myenteric neurones. Neurogastroenterol Motil. 2010 Jan 22:98-107, e33.

HUNT, D.Kanji JN, Anglin RE, Hunt DL, Panju A. Does this patient with dia-betes have large-fiber peripheral neuropathy? JAMA. 2010 Apr 21;303(15):1526-32.

INGRAM, A.Peng F, Zhang B, Ingram AJ, Gao B, ZhangY, Krepinsky JC. Mechanical Stretch-Induced RhoA Activation is Mediated by the RhoGEF Vav2 in Mesangial Cells. Cell Signal. 2010 Jan;22(1):34-40.

He L, Ingram AJ, Rybak AP, Tang D. Shank-interacting protein-like 1 (SIPL1) reduces PTEN function during tumorigenesis. J Clin Invest. 2010;120(6):2094-108.

Zhang Y, Peng F, Gao B, Ingram AJ, Krepinsky JC. Mechanical strain-induced RhoA activation requires NADPH oxidase-medi-ated ROS generation in caveolae. Antioxid Redox Signal. 2010 Oct 1;13(7):959-73.

JAESCHKE, R.Guyatt G, Oxman AD, Akl EA, Kunz R, Vist G, Brozek J, Norris S, Falck-Ytter Y, Glasziou P, Debeer H, Jaeschke R, Rind D, Meerpohl J, Dahm P, Schünemann HJ. GRADE guidelines: 1. Introduction – GRADE evidence profiles and summary of findings tables. J Clin Epidemiol. 2011 Apr;64(4):383-94. Epub 2010 Dec 31.

Nunnally ME, Jaeschke R, Bellingan GJ, Lacroix J, Mourvillier B, Rodriguez-Vega GM, Rubertsson S, Vassilakopoulos T, Weinert C, Zanotti-Cavazzoni S, Buchman TG. Targeted temperature manage-ment in critical care: A report and recommendations from five pro-fessional societies. Crit Care Med. 2011 May;39(5):1113-25. Epub 2010 Dec 23.

Guyatt G, Akl EA, Hirsh J, Kearon C, Crowther M, Gutterman D, Lewis SZ, Nathanson I, Jaeschke R, Schünemann H. The vexing problem of guidelines and conflict of interest: a potential solution. Ann Intern Med. 2010 Jun 1;152(11):738-41.

JANSSEN, L.Ghayur MN, Janssen LJ. A natural way forward to cardiovascular health. Nat Rev Cardiol. 2010 Mar;7(3):1-2.

Khan MA, Ellis R, Inman MD, Bates JH, Sanderson MJ, Janssen LJ. Influence of airway wall stiffness and parenchymal tethering on the dynamics of bronchoconstriction. Am J of Physiol Lung Cell Mol Physiol. 2010 Jul;299(1):L98-L108.

JOHNSTONE, J.Johnstone J, Nerenberg K, Loeb M. Proton pump inhibitor use and risk of community acquired pneumonia: a systematic review and meta-analysis. Aliment Pharmacol Ther. 2010 Jun;31(11):1165-77. Epub 2010 Mar 4.

Johnstone J, Eurich DT, Minahs JK, Marrie TJ, Majumdar SR. Impact of pneumococcal vaccine on long-term morbidity and mor-tality of adults at high-risk for pneumonia. Clin Infect Dis. 2010 Jul 1;51(1):15-22.

JOLLY, S.Steg PG, Mehta S, Jolly SS, Xavier D, Rupprecht HJ, Lopez-Sendon JL, Chrolavicius S, Rao SV, Granger CB, Pogue J, Laing S, Yusuf S. Fondaparinux with UnfracTionated heparin dUring Revascularization in Acute coronary syndromes (FUTURA/OASIS 8): a randomized trial of intravenous unfractionated heparin during percutaneous coronary intervention in patients with non-ST-seg-ment elevation acute coronary syndromes initially treated with fondaparinux. Am Heart J. 2010 Dec;160(6):1029-34, 1034.e1.

Rousseau M, Yan RT, Tan M, Lefkowitz CJ, Casanova A, Fitchett D, Jolly SS, Langer A, Goodman SG, Yan AT; Integrilin and Enoxaparin Randomized Assessment of Acute Coronary Syndrome Treatment (INTERACT) Trial Investigators. Relation between hemoglobin level and recurrent myocardial ischemia in acute coronary syndromes detected by continuous electrocardiographic monitoring. Am J Cardiol. 2010 Nov 15;106(10):1417-22.

Bertrand OF, Rao SV, Pancholy S, Jolly SS, Rodes-Cabau J, Larose E, Costerousse O, Hamon M, Mann T. Transradial approach for coronary angiography and interventions: results of the first inter-national transradial practice survey. JACC Cardiovasc Interv. 2010 Oct;3(10):1022-31.

CURRENT-OASIS 7 Investigators, Mehta SR, Bassand JP, Chrolavicius S, Diaz R, Eikelboom JW, Fox KA, Granger CB, Jolly SS, Joyner CD, Rupprecht HJ, Widimsky P, Afzal R, Pogue J, Yusuf S. Dose comparisons of clopidogrel and aspirin in acute coronary syndromes. N Engl J Med. 2010 Sep 2;363(10):930-42. Erratum in: N Engl J Med. 2010 Oct 14;363(16):1585.

FUTURA/OASIS-8 Trial Group, Steg PG, Jolly SS, Mehta SR, Afzal R, Xavier D, Rupprecht HJ, Lopez-Sendon JL, Budaj A, Diaz R, Avezum A, Widimsky P, Rao SV, Chrolavicius S, Meeks B, Joyner C, Pogue J, Yusuf S. Low-dose vs standard-dose unfractionated heparin for percutaneous coronary interventino in acute coronary syndromes treated with fondaparinux: the FUTURA/OASIS-8 ran-domized trial. JAMA. 2010 Sep 22;304(12):1339-49.

Mehta SR, Tanguay JF, Eikelboom JW, Jolly SS, Joyner CD, Granger CB, Faxon DP, Rupprecht HJ, Budaj A, Avezum A, Widimsky P, Steg PG, Bassand JP, Montalescot G, Macaya C, Di Pasquale G, Niemela K, Ajani AE, White HD, Chrolavicius S, Gao P, Fox KA, Yusuf S. Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial. Lancet. 2010 Oct 9;376(9748):1233-43.

Mehta S, Bassand JP, Chrolavicius S, Diaz R, Eikelboom JW, Fox KA, Granger CB, Jolly S, Joyner CD, Rupprecht HJ, Widimsky P, Afzal R, Pogue J, Yusuf S. Dose comparisons of clopidogrel and aspirin in acute coronary syndromes. N Engl J Med. 2010 Sep 2:363(10):930-42.

Jolly SS, Yusuf S. Which antithrombotic to use during PCI? Eur Heart J. 2010 Mar;31(5):522-4.

136

PUBLICATIONS

Leber B, Andrews DW. Closing in on the link between apoptosis and autophagy. Biol Rep. 2010 Dec 17;2:88.

LEONTIADIS, G.Barkun AN, Bardou M, Kuipers EJ, Sung J, Hunt RH, Martel M, Sinclair P; International Consensus Upper Gastrointestinal Bleeding Conference Group. International consensus recommen-dations on the management of patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med. 2010 Jan 19;152(2):101-13.

Barkun A, Leontiadis GI. Systematic review of the symptom bur-den, quality of life impairment and costs associated with peptic ulcer disease. Am J Med 2010; 123(4):358-66.e2.

Sreedharan A, Martin J, Leontiadis GI, Dorward S, Howden CW, Forman D, Moayyedi P. Proton pump inhibitor treatment initiated prior to endoscopic diagnosis in upper gastrointestinal bleed-ing. Cochrane Database of Systematic Reviews. 2010 Jul 7;(7):CD005415.

Dionisio PM, Gurudu SR, Leighton JA, Leontiadis GI, Fleischer DE, Hara AK, Heigh RI, Shiff AD, Sharma VK. Capsule Endoscopy Has a Significantly Higher Diagnostic Yield in Patients With Suspected and Established Small-Bowel Crohn’s Disease: A Meta-Analysis. American Journal of Gastroenterology. 2010;105(6):1240-8; quiz 1249.

Leontiadis GI, Tse F, Howden CW. Antiplatelet therapy in patients with atherosclerotic coronary artery disease undergoing elective endoscopic gastrointestinal procedures. Key messages for clinical practice. Polish Archives of Medicine Wewn. 2010;120(4):143-7.

LIM, W.Choong K, Cupido C, Nelson E, Arnold DM, Burns K, Cook D, Meade M, ACCADEMY Collaborators (Adhikari N, Duffett M, Koo K, Lamontagne F, Lim W). A framework for resolving disagreement during end of life care in the critical care unit. Clin Invest Med. 2010 Aug 1;33:E240-53.

Lim W. Using low molecular weight heparin in special patient pop-ulations. J Thromb Thrombolysis. 2010;29:233. Epub 2009 Nov 10.

Crowther M, Lim W, Crowther MA. Systematic review and meta-analysis methodology. Blood. 2010;116:3140-6. Epub 2010 July 23.

LIMA, H.de Carvalho VO, Cruz CR, Noronha L, Abagge KT, Lima HC. An inflammatory reaction surrounding molluscum contagiosum as possible manifestation of immune reconstitution inflammatory syn-drome in HIV infection. Pediatr Dermatol. 2010 Nov-Dec;27(6):631-4.

Lima XT, Kimball AB, Lima HC, de Souza RC, de Carvalho VO. Assessing dermatology board examination competence using questions distribution: a 12-year Brazilian experience. Int J Dermatol. 2010 Sep;49(9):1080-2.

Lima HC, Kimball AB. Targeting IL-23: Insights into the patho-genesis and the treatment of psoriasis. Indian J of Dermatol. 2010;55(2):171-5.

Laboratorial atopy markers in children with human immunodefi-ciency virus. Cruz CR, Carvalho VO, Santos RV, Tahan TT, Rossoni AM, Lima HC. Mem Inst Oswaldo Cruz. 2010;105(3):293-8.

LINKINS, L.Linkins LA, Weitz JI. New and emerging anticoagulant therapies for venous thromboembolism. Curr Treat Options Cardiovasc Med. 2010 Apr;12(2):142-55.

Linkins L, O’Donnell M, Julian JA, Kearon C. Intracranial and fatal bleeding according to indication for long-term oral anticoagulant therapy. J Thromb Haemost. 2010 Oct 8(10):2201-7.

Warkentin TE, Linkins LA. Non-necrotizing heparin-induced skin lesions and other refinements to the 4T’s scoring system. J Thromb Haemost. 2010 Jul;8(7):1483-5.

Kerr J, Linkins L. High incidence of in-hospital pulmonary embolism following joint arthroplasty with dalteparin prophylaxis: a chart review. Thromb Haemost. 2010;103:123-8.

LONN, E.Saposnik G, Redelmeier D, Lu H, Fuller-Thomsom E, Ray J, Lonn E. Premature Risk of Stroke in Recent Immigrants (PRESARIO): Population-based matched cohort study. Neurology; 2010 Feb 9;74(6):451-7. Epub 2010 Feb 3.

Saposnik G, Redelmeier D, Lu H, Fuller-Thomsom E, Lonn E, Ray J. Myocardial infarction Associated with Recency of Immigration to Ontario (MARIO). QJM. 2010 Apr;103(4):253-8. Epub 2010 Feb 18.

Lonn E. Lipoprotein-associates phospholipase A2: a new therapeu-tic target. Can J Cardiol. 2010;26 Suppl A:26A-32A.

Böhm M, Baumhäkel M, Teo K, Sleight P, Probstfield J, Gao P, Mann JF, Diaz R, Dagenais GR, Jennings GL, Liu L, Jansky P, Yusuf S; ONTARGET/TRANSCEND Erectile Dysfunction Substudy Investigators. Erectile dysfunction predicts cardiovascular events in high-risk patients receiving telmisartan, ramipril, or both: The ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial/Telmisartan Randomized AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease (ONTARGET/TRANSCEND) Trials. Circulation. 2010 Mar 30;121(12):1439-46. Epub 2010 Mar 15.

Clarke R, Halsey J, Lewington S, Lonn E, Armitage J, Manson AE, Bonaa KH, Spence DJ, Nygard O, Jamison R, Gaziano MJ, Guarino P, Bennett D, Mir F, Peto R, Collins R on behalf of the B-Vitamin Treatment Trialists’ Collaboration. Effects of homocysteine-low-ering with B-vitamins on cardiovascular disease, cancer and cause-specific mortality: meta-analysis of 8 randomized trials involving 37,485 individuals. Archives of Intern Med. 2010 Oct 11;170(18):1622-3.

Bhan V, Goodman SG, Yan RT, Leiter LA, Fitchett D, Langer A, Lonn EM, Tan M. Silagy S, Yan AT. Obesity is Associated With Failure to Attain Optimal Blood Pressure and Lipid Targets in High Vascular Risk Outpatients. Am J Cardiol. 2010 Nov 1;106(9):1270-6.

Lonn E, Bosch J, Teo KK, Pais P, Xavier D, Yusuf S. The Polypill in the Prevention of cardiovascular diseases: key concepts, current status, challenges, and future directions. Circulation. 2010;122:2078-88.

Ismail-Beigi F, Craven T, Banerji MA, Basile J, Calles J, Cohen RM, Cuddihy R, Cushman WC, Genuth S, Grimm RH Jr, Hamilton BP, Hoogwerf B, Karl D, Katz L, Krikorian A, O’Connor P, Pop-Busui R, Schubart U, Simmons D, Taylor H, Thomas A, Weiss D, Hramiak I; ACCORD trial group. Effect of intensive treatment of hyperglycae-mia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial. Lancet 2010;376(9739):419-30.

ACCORD Study Group; ACCORD Eye Study Group, Chew EY, Ambrosius WT, Davis MD, Danis RP, Gangaputra S, Greven CM, Hubbard L, Esser BA, Lovato JF, Perdue LH, Goff DC Jr, Cushman WC, Ginsberg HN, Elam MB, Genuth S, Gerstein HC, Schubart U, Fine LJ. Effects of medical therapies on retinopathy progression in type 2 diabetes. N Engl J Med. 2010;363(3):233-44.

ACCORD Study Group, Cushman WC, Evans GW, Byington RP, Goff DC Jr, Grimm RH Jr, Cutler JA, Simons-Morton DG, Basile JN, Corson MA, Probstfield JL, Katz L, Peterson KA, Friedewald WT, Buse JB, Bigger JT, Gerstein HC, Ismail-Beigi F. Effects of intensive blood-pressure control in type 2 diabetes mellitus. N Engl J Med. 2010;29;362(17):1575-85.

ACCORD Study Group, Ginsberg HN, Elam MB, Lovato LC, Crouse JR 3rd, Leiter LA, Linz P, Friedewald WT, Buse JB, Gerstein

Walker JG, Steele RJ, Schnitzer M, Taillefer S, Baron M; Canadian Scleroderma Research Group (N. Khalidi as part of CSRG), Hudson M. The association between disease activity and duration in system-ic sclerosis. J Rheumatol. 2010 Nov;37(11):2299-306. Epub 2010 Sep 1.

Hudson M, Impens A, Baron M, Seibold JR, Thombs BD, Walker JG; Canadian Scleroderma Research Group (N. Khalidi as part of CSRG), Steele R. Discordance between patient and physi-cian assessments of disease severity in systemic sclerosis. J Rheumatol. 2010 Nov;37(11):2307-12. Epub 2010 Sep 15.

El-Baalbaki G, Razykov I, Hudson M, Bassel M, Baron M, Thombs BD; Canadian Scleroderma Research Group (N. Khalidi as part of CSRG). Association of pruritus with quality of life and dis-ability in systemic sclerosis. Arthritis Care Res (Hoboken). 2010 Oct;62(10):1489-95.

Hudson M, Masetto A, Steele R, Arthurs E, Baron M; Canadian Scleroderma Research Group (N. Khalidi as part of CSRG). Reliability of widefield capillary microscopy to measure nailfold capillary density in systemic sclerosis. Clin Exp Rheumatol. 2010 Sep-Oct;28(5 Suppl 62):S36-41. Epub 2010 Nov 3.

Fan X, Pope J; Canadian Scleroderma Research Group (N. Khalidi as part of CSRG), Baron M. What is the relationship between disease activity, severity and damage in a large Canadian sys-temic sclerosis cohort? Results from the Canadian Scleroderma Research Group (CSRG). Rheumatol Int. 2010 Jul;30(9):1205-10. Epub 2009 Sep 24.

Milette K, Hudson M, Baron M, Thombs BD; Canadian Scleroderma Research Group (N. Khalidi as part of CSRG). Comparison of the PHQ-9 and CES-D depression scales in systemic sclerosis: internal consistency reliability, convergent validity and clinical correlates. Rheumatology (Oxford). 2010 Apr;49(4):789-96. Epub 2010 Jan 25.

Baron M, Hudson M, Steele R; Canadian Scleroderma Research Group (N. Khalidi as part of CSRG). Is serum albumin a marker of malnutrition in chronic disease? The scleroderma paradigm. J Am Coll Nutr. 2010 Apr;29(2):144-51.

Schieir O, Thombs BD, Hudson M, Boivin JF, Steele R, Bernatsky S, Hanley J, Baron M; Canadian Scleroderma Research Group (N. Khalidi as part of CSRG). Prevalence, severity, and clinical corre-lates of pain in patients with systemic sclerosis. Arthritis Care Res (Hoboken). 2010 Mar;62(3):409-17.

Sekhon S, Pope J; Canadian Scleroderma Research Group (N. Khalidi as part of CSRG), Baron M. The minimally important differ-ence in clinical practice for patient-centered outcomes including health assessment questionnaire, fatigue, pain, sleep, global visual analog scale, and SF-36 in scleroderma. J Rheumatol. 2010 Mar;37(3):591-8. Epub 2010 Jan 15.

KILLIAN, K.Agusti A, Calverley PM, Celli B, Coxson HO, Edwards LD, Lomas DA, MacNee W, Miller BE, Rennard S, Silverman EK, Tal-Singer R, Wouters E, Yates JC, Vestbo J; Characterisation of COPD hetero-geneity in the ECLIPSE cohort. Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators. Respir Res. 2010 Sep 10;11:122.

Gauvreau GM, Boulet LP, Cockcroft DW, Fitzgerald JM, Carlsten C, Davis BE, Deschesnes F, Duong M, Durn BL, Howie KJ, Hui L, Kasaian MT, Killian KJ, Strinich TX, Watson RM, Y N, Zhou S, Raible D, O’Byrne PM. The effects of IL-13 blockade on allergen-induced airway responses in mild atopic asthma. Am J Respir Crit Care Med. Epub 2010 Nov 5.

KOLB, M.Rodt T, von Falck C, Dettmer S, Halter R, Maus R, Ask K, Kolb MRJ, Gauldie J, Laenger F, Hoy L, Welte T, Galanski M, Maus UA, Borlak J. Micro-computed tomography of pulmonary fibrosis in mice

induced by adenoviral gene transfer of biologically active TGFβ1. Respir Res. 2010 Dec 22;11(1):181.

Farkas L, Farkas D, Gauldie J, Warburton D, Shi W, Kolb MRJ. Transient Over-expression of Gremlin Results in Epithelial Activation and Reversible Fibrosis in Rat Lungs. Am J Respir Cell Mol Biol. Epub 2010 Aug 12.

Patel P, Sekiguchi Y, Oh KH, Patterson SE, Kolb MRJ, Margetts PJ. SMAD 3 dependent and independent pathways are involved in peritoneal membrane injury. Kidney Int. 2010 Feb;77 (4):319-28.

Tarantal AF, Chen H, Shi TT, Lu C-H, Fang AB, Buckely S, Kolb MRJ, Gauldie J, Warburton D, Shi W. Over-expression of TGF-β1 in fetal monkey lung results in prenatal pulmonary fibrosis. Eur Respir J. 2010 Oct;36(4):907-1.

Farkas L, Gauldie J, Voelkel NF, Kolb MRJ. Pulmonary Hypertension and Idiopathic Pulmonary Fibrosis-A Tale of Angiogenesis, Apoptosis and Growth Factors. Am J Respir Cell Mol Biol. Epub 2010 Nov 5.

Ask K, Eickelberg O, Gauldie J, Kaminski N, Kolb MRJ. Have advanced research technologies made real impact on respiratory medicine? Respirology. 2010 Aug;15(6):876-80.

Antoniu SA, Kolb MRJ. Intedanib, a triple kinase inhibitor of VEGFR, FGFR, and PDGFR for the treatment of cancer and idiopathic fibro-sis. IDrugs. 2010 May;13(5):332-44.

Farkas L, Kolb MRJ. Endothelial Progenitor Cells as a Target for Therapy of Pulmonary Hypertension. CML Pulmonary Hypertension. 2010;1(3):61-8.

Amlani S, Richeldi L, Kolb MRJ. Management of IPF Minerva Pnuemologica. 2010;49(1):73-82.

KREPINSKY, J.Peng F, Zhang B, Ingram AJ, Gao B, Zhang Y, Krepinsky JC. Mechanical Stretch-Induced RhoA Activation is Mediated by the RhoGEF Vav2 in Mesangial Cells. Cell Signal. 2010;22(1):34-40.

Zhang Y, Peng F, Gao B, Ingram AJ, Krepinsky JC. Mechanical Strain-Induced RhoA Activation Requires NADPH-Mediated ROS Generation in Caveolae. Antiox Redox Signal. 2010;13(7):959-73.

LARCHÉ, MARGARETLarche MJ, Roth J. Towards standardised ultrasound measure-ments of cartilage thickness in children. J Rheum. 2010;12:2445-7.

LEBER, B.Crump M, Hedley D, Kamel-Reid S, Leber B, Wells R, Brandwein J. Buckstein R, Kassis J, Minden M, Matthews J, Robinson S, Turner R, McIntosh L. Eisenhauer E, Seymour L. A randomized phase I clinical and biologic study of two schedules of sorafenib in patients with myelodysplastic syndrome or acute myeloid leu-kemia, a NCIC (National Cancer Institute of Canada) Clinical Trials Group Study. Leuk Lymphoma. 2010 Feb:51(2):252-60.

Campbell CJ, Lee JB, Levadoux-Martin M, Wynder T, Xenecostas A, Leber B, Bhatia M. The human stem cell hierarchy is defined by a functional dependence on Mcl-1 for self-renewal capacity. Blood. 2010 Sept 2;116(9):1433-2. Epub 2010 June 4.

Bogner C, Leber B, Andrews DW. Apoptosis: embedded in mem-branes. Curr Opin Cel Biol. Epub 2010 Aug 26.

Leber B, Geng F, Kale J, Andrews DW. Drugs targeting Bcl-2 family members as an emerging strategy in cancer. Expert Reviews in Molecular Medicine. 2010 Sep 8;12:e28.

138

PUBLICATIONS

Volpe M, McKelvie R, Drexler H. Hypertension as an underlying factor in heart failure with preserved ejection fraction. J Clin Hypertension (Greenwich). 2010;12:277-83.

Zile MR, Gaasch Wm H, Anand IS, Haass M, Little Wm C, Miller AB, Lopez-Sendon J, Teerlink RJ, White M, McMurray JJ, Komajda M, McKelvie R, Ptaszynska A, Hetzel SJ, Massie BM, Carson PE, for the I-Preserve Investigators. Mode of death in patients with heart failure and a preserved ejection fraction: results from irbesartan in heart failure with preserved ejection fraction study (I-PRESERVE) Trial. Circulation. 2010;121:1395-405.

Kuenzli A, Bucher HC, Anand I, Arutiunov G, Kum LC, McKelvie R, Afzal R, White M, Nordmann AJ. Meta-analysis of combined ther-apy with angiotensin receptor antagonists versus ACE inhibitors alone in patients with heart failure. PLos ONE. 2010;5(4):e9946.

Howlett JG, McKelvie RS, Costigan J, Ducharme A, Estrella-Holder E, Ezekowitz JA, Giannetti N, Haddad H, Heckman GA, Herd AM, Isaac D, Jong P, Kouz S, Leblanc K, Liu P, Mann E, Moe GW, O’Meara E, Rajda M, Siu S, Stolee P, Swiggum E, Zeiroth S. The 2010 Canadian Cardiovascular Society Guidelines for the diag-nosis and management of heart failure update: Heart Failure in Ethnic Minority Populations, Heart Failure and Pregnancy, Disease Management, and Quality Improvement/Assurance Programs. Can J Cardiol. 2010;26:185-202.

Makdessi A, Harkness K, Luttik ML, McKelvie RS. The Dutch Objective Burden Inventory: Validity and reliability in a Canadian population of caregivers for people with heart failure. Eur J Cardiovasc Nurs. Epub 2010 Oct 2.

Jong P, McKelvie R, Yusuf S. Should treatment for heart failure with preserved ejection fraction differ from that for heart failure with reduced ejection fraction. BMJ. 2010 Aug 25;341:c4202.

McKelvie RS. Exercise training in patients with heart failure: Clinical outcomes. CICRP. 2010;18(2):5-8.

MEADE, M.Sud S, Sud M, Friedrich JO, Meade MO, Ferguson ND, Wunsch H, Adhikari NKJ. High frequency oscillation in acute lung injury and acute respiratory distress syndrome(ARDS): systematic review and meta-analysis. BMJ. 2010 May 18;340:c2327.

Crowther MA, Cook DJ, Albert M, Williamson D, Meade M, Granton J, Skrobik Y, Langevin S, Mehta S, Hebert PC, Guyatt GH, Geerts W, Rabbat C, Douketis J, Zytaruk N, Sheppard J, Greinacher A, Warkentin TE for the Canadian Critical Care Trials Group. The 4Ts Scoring System for Heparin Induced Thrombocytopenia in Medical-Surgical ICU Patients. J Crit Care. 2010 Jun;25(2):287-93. Epub 2010 Feb 10.

Briel M, Meade MO, Mercat A, Brower RG, Talmor D, Walter SD, Slutsky AS, Pullenayegum E, Zhou Q, Cook DJ, Brochard L, Richard JM, Lamontagne F, Bhatnagar N, Stewart TE, Guyatt GH. Higher versus lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: sys-tematic review and individual patient data meta-analysis. JAMA. 2010;303(9):865-73.

Burns KEA, Adhikari NKJ, Keenan SP, Meade MO. Noninvasive positive pressure ventilation as a weaning strategy for intubated adults with respiratory failure. Cochrane Database Syst Rev. 2010 Aug 4;(8):CD004127. Review.

Kirkpatrick AW, Pelosi P, De Waele J, Malbrain MLNG, Ball CB, Meade MO, Laupland KB, Stelfox HT. Intra-abdominal hyperten-sion: Does it influence the physiology of prone ventilation? Crit Care. 2010;14:232.

Choong K, Cupido C, Meade M, Arnold D, Burns K, Nelson E, Cook D. A framework for resolving disagreement during end of life care in the critical care unit. Clin Invest Med. 2010 Aug 1;33(4):E240-53.

Lamontagne F, Briel M, Guyatt GH, Cook DJ, Bhatnagar N, Meade MO. Corticosteroid therapy for acute lung injury, acute respiratory distress syndrome, and severe pneumonia: A meta-analysis of ran-domized controlled trials. J Crit Care. 2010 Sep;25(3):420-35. Epub 2009 Nov 5. Review.

MEHTA, S.Anderson JA, Hirsh J, Yusuf S, Johnston M, Afzal R, Mehta SR, Fox KA, Budaj A, Eikelboom JW. Comparison of the anticoagulant intensities of fondaparinux and enoxaparin in the Organization to Assess Strategies in Acute Ischemic Syndromes (OASIS)-5 trial. J Thromb Haemost. 2010 Feb;8(2):243-9. Epub 2009 Nov 26.

Bainey KR, Mehta SR. Aspirin for Acute Coronary Syndromes: Have we Learned the Correct Dose Yet? Curr Cardiol Rep. 2010;12(4):344-7.

Mehta SR, Bassand JP, Chrolavicius S, Diaz R, Eikelboom JW, Fox KAA, Granger CB, Jolly S, Joyner C, Rupprecht HJ, Widimsky P, Afzal R, Pogue J, Yusuf S. Dose Comparisons of Clopidogrel and Aspirin in Acute Coronary Syndromes. N Engl J Med. 2010;363:930-42.

Mehta SR, Tanguay JF, Eikelboom JW, Jolly SS, Joyner CD, Granger CB, Faxon DP, Rupprecht HJ, Budaj A, Avezum A Widimsky, Steg PG, Bassand JP, Montalescot G, Macaya C, Di Pasquale G, Niemela K, Anjani AE, White HD, Chrolavicius S, Gao P, Fox KAA, Yusuf S. Double-dose versus standard-dose clopido-grel and high-dose versus low-dose aspirin in individuals undergo-ing percutaneous coronary intervention for acute coronary syn-dromes (CURRENT-OASIS7): a randomized factorial trial. Lancet. 2010;376:1233-43.

Pare G, Mehta SR, Yusuf S, Anand S, Connolly SJ, Hirsh J, Simonsen K, Bhatt DL, Fox KAA, Eikelboom JW. Effects of CYP2C19 Genotype on Outcomes of Clopidogrel Treatment. N Engl J Med. Epub 2010 Aug 29.

Steg, PG, Jolly SS, Mehta SR, Afzal R, Xavier D, Rupprecht HJ, Lopex-Sendon JL, Budaj A, Diaz R, Avezum A, Widmisky P,Rao SV, Chrolavicius S, Meeks B, Joyner C, Pogue J, Yusuf S. Low-Dose vs Standard Dose Unfractionated Heparin for Percutaneous Coronary Intervention in Acute Coronary Syndromes Treated with Fondaparinux: The FUTURA/OASIS-8 Randomized Trial. JAMA. Epub 2010 Aug 31.

Paikin JS, Mehta SR, Eikelboom JW. Role of triple antithrombotic therapy in patients with atrial fibrillation and coronary artery stents. Med J Aust. 2010;192(9):487-8.

Paikin JS, Wright DS, Crowther MA, Mehta SR, Eikelboom JW. Triple antithrombotic therapy in patients with atrial fibrillation and coronary artery stents. Circulation. 2010;121(18):2067-70.

Steg PG, Mehta, S, Jolly SS, Xavier D, Rupprecht HJ, Lopez-Sendon JL, Chrolavicius S, Rao SV, Granger SB, Pogue J, Laing S, Yusuf S. Fondaparinux with UnfracTionated heparin dUring Revascularization in Acute coronary syndromes (FUTURA/Oasis 8): A randomized trial of intravenous unfractionated heparin during percutaneous coronary intervention in patients with non-ST-seg-ment elevation acute coronary syndromes initially treated with fondaparinux. Am Heart J. 2010;160(6):1029-34.

van Rees Vellinga TE, Peter RJG, Yusuf, S, Afzal R, Chrolavicius S, O’Donnell M, Mehta SR, Eikelboom, JW. Efficacy and safety of fondaparinux in patients with ST-segment elevation myocardial infarction across the age spectrum. Results from the Organization for the Assessment of Strategies for Ischemic Syndromes 6 (OASIS-6) trial. Am Heart J. 2010;160(6):1049-55.

Bassand JP, Afzal R, Eikelboom J, Wallentin L, Peters R, Budj A, Fox KA, Joyner CD, Chrolavicius S, Granger CB, Mehta S, Yusuf S, on behalf of the OASIS 5 and OASIS 6 Investigators. Relationship between baseline haemoglobin and major bleeding complications in acute coronary syndromes. Eur Heart J. 2010 Jan;31(1):50-8.

HC, Probstfield J, Grimm RH, Ismail-Beigi F, Bigger JT, Goff DC Jr, Cushman WC, Simons-Morton DG, Byington RP. Effects of combination lipid therapy in type 2 diabetes. N Engl J Med. 2010;362(17):1563-74.

MARGETTS, P.Su WS, Clase CM, Brimble KS, Margetts PJ, Wilkieson TT, Gangji AS. Waist-to-hip ratio, Cardiovascular Outcomes, and Death in Peritoneal Dialysis Patients. Int J Nephrol. 2010;Jul 5;2010:831243.

Oh K-W, Youn MO, Song A, Hwang Y-H, Margetts PJ, Lee H, Ahn C, Gu C. Dialysate interleukin-6 as the determinant factor of the baseline peritoneal solute transport in incident peritoneal dialysis patients. Nephrol Dial Transplant. 2010;25:1639-46.

Patel P, West-Mays J, Kolb M, Rodrigues JC, Hoff CM, Margetts PJ. Platelet derived growth factor B and epithelial mesenchymal transition of peritoneal mesothelial cells. Matrix Biol. 2010;29:97-106.

Patel P, Sekiguchi Y, Oh K-W, Kolb M, Margetts PJ. Smad3 depen-dent and independent pathways are involved in peritoneal mem-brane injury. Kidney Int. 2010;77:319-28.

Salama S, Cina DP, Margetts PJ. Cutaneous Presentation of Post-Renal Transplant Lymphoproliferative Disorder: A Case Series.J Cutan Pathol. 2010 Jun;37(6):641-53. Epub 2009 Nov 9.

MARSHALL, J.Barkun A, Bardou M, Kuipers E, Sung J, Martel M, Sinclair, International Consensus Upper GI Bleeding Consensus Group. International consensus recommendations on the management of patients with non-variceal upper gastrointestinal bleeding. Ann Intern Med. 2010;152:101-13.

Marshall JK, Thabane M, Steinhart AH, Newman J, Anand A, Irvine EJ. Rectal 5-aminosalicylic acid for induction of remission of ulcer-ative colitis. Cochrane Database Syst Rev. 2010;Jan 20(1):CD004115.

Narula N, Yamamura DLR, Marshall JK. Should my patient with inflammatory bowel disease on immunosuppressive therapy be vaccinated against influenza virus? Can J Gastroenterol. 2010;24:121-5.

Villani AC, Lemire M, Thabane M, Geneau G, Belisle A, Garg AX, Clark WF, Moayyedi P, Collins SM, Franchimont D, Marshall JK. Genetic risk factors for post-infectious irritable bowel syndrome following a waterborne outbreak of gastroenteritis. Gastroenterology. 2010;138:1502-13.

Ford AC, Thabane M, Collins SM, Moayyedi P, Garg AX, Clark WF, Marshall JK. Prevalence of uninvestigated dyspepsia eight years after a large waterborne outbreak of bacterial dysentery: cohort study. Gastroenterology. 2010;138:1727-36.

Thabane M, Simunovic M, Akhtar-Danesh N, Garg AX, Clark WF, Collins SM, Salvadori M, Marshall JK. An outbreak of acute bac-terial gastroenteritis is associated with an increased incidence of irritable bowel syndrome in children. Am J Gastroenterol. 2010;105:933-9.

Assasi N, Blackhouse G, Xie F, Marshall JK, Irvine EJ, Gaebel K, Robertson D, Campbell K, Hopkins R, Goeree R. Patient outcomes after anti-TNF-alpha therapy for Crohn’s disease: a system-atic review and meta-analysis. Pharmacoecon Outcome Res. 2010;10:163-75.

Marshall JK, Thabane M, Garg AX, Clark WF, Moayyedi P, Collins SM. Eight-year prognosis of post-infectious irritable bowel syn-drome following waterborne bacterial dysentery. Gut. 2010;59:605-11.

Narula N, Vasudev M, Marshall JK. IgG4-related sclerosing dis-ease: a novel mimic of inflammatory bowel disease. Dig Dis Sci. 2010;55:3047-55.

Narula N, Marshall JK. The role of probiotics in management of diverticular disease. J Gastroenterol Hepatol. 2010;25:1827-30.

MAZUREK, M.Skoblenick K, Xu Y, Ki K, Castellano J, Dyck B, Chong V, Mazurek M, Mishra R. Role of AP-2a transcription factor in the regulation of synapin II Gene expression by dopamine D1 and D2 receptors. Journal of Molecular Neuroscience. 2010 Jun;41(2):267-77.

Rosebush PI, Mazurek MF. Catatonia and its treatment. Schizophrenia Bulletin. 2010 Mar;36(2):239-42.

Anglin R, Rosebush PI, Mazurek MF. Treating psychiatric illness in patients with mitochondrial disorders. Psychosomatics. 2010 Mar;51(2):179.

Anglin R, Rosebush PI, Mazurek MF. Neuroleptic Malignant Syndrome: A Neuroimmunologic Hypothesis. Canadian Medical Association Journal. 2010;182(18): E834-8.

MacGillivray L, Lagrou LM, Reynolds KB, Rosebush PI, Mazurek MF. Role of serotonin transporter inhibition in the regulation of tryptophan hydroxylase in brainstem raphe nuclei: time course and regional specificity. Neuroscience. 2010;171(2):407-20.

MCIVOR, A.Chapman K, McIvor RA. Asthma that is unresponsive to usual care. CMAJ. 2010;182:45-52.

Hodder R, Lougheed MD, Rowe BH, Fitzgerald JM, Kaplan AG, McIvor RA. Management of acute asthma in adults in the emergen-cy department: nonventilatory management. CMAJ. 2010 182: E55-67.

Hodder R, Lougheed D, Fitzgerald JM, Rowe BH, Kaplan AG, McIvor RA. Management of acute asthma in adults in the emer-gency department: assisted ventilation. CMAJ. 2010;182:265-72.

Kovesi T, Schuh S, Spier S, Berube D, Carr S, Watson W, McIvor RA. Achieving control of asthma in preschoolers. CMAJ. 2010;182:E172-E183.

Gelberg J, McIvor RA. Overcoming gaps in the management of COPD in the older patients. New Insights Drugs Aging. 2010 May;27(5):367-75.

Pakhale, S, Doucette S, Vandemheen KL, Boulet LP, McIvor RA, FitzGerald JM, Hernandez P, Lemiere C, Sharma S, Field SK, Gonzalo G. Alvarez, Dales RE, Aaron SD. A comparison of Obese and Non-Obese asthmatics: Exploring an asthma obesity interac-tion. Chest. 2010 Jun;137(6):1316-23.

Cui Q, Carruthers S, McIvor RA, Smaill F, Thabane L, Smieja M. Effect of Smoking on Lung Function, Respiratory Symptoms and Respiratory Diseases amongst HIV-Positive Subjects: a cross-sec-tional study. AIDS Res Ther. 2010 Mar 19;7(1):6.

Al-Ghimas F, McIvor RA. Evaluation of a Novel Method to Assess Corticosteroid-Responsiveness in Chronic Obstructive Pulmonary Disease. Ann Thorac Med. 2010 Oct;5(4):232-7.

Johnston NW, McIvor A, Lambert K, Greene J, Hussack P, Gerhardsson de Verdier M, Higenbottam T, Lewis J, Newbold P, Astbury C, Herath A. The Christmas season as a risk factor for chronic obstructive pulmonary disease exacerbations. Can Respir J. 2010:16(6):275-81.

MCKELVIE, R.McKelvie RS, Komajda M, McMurray J, Zile M, Ptaszynska A, Donovan M, Carson P, Massie BM, for the I-PRESERVE Investigators. Baseline plasma NT-proBNP and clinical character-istics: Results from the irbesartan in heart failure with preserved ejection fraction trial. J Cardiac Fail. 2010;16:128-34.

140

PUBLICATIONS

Sinha AM, Diener HC, Morillo CA, Sanna T, Bernstein RA, Di Lazzaro V, Passman R, Beckers F, Brachmann J. Cryptogenic Stroke and underlying Atrial Fibrillation (CRYSTAL AF): design and rationale. Am Heart J. 2010 Jul;160(1):36-41.e1.

Healey JS, Nair GM, Connolly SJ, Morillo CA. A rare cause of implantable cardioverter-defibrillator failure: short-circuiting via an unused pace/sense lead. Heart Rhythm. 2010 Nov;7(11):1630-1. Epub 2010 Jul 21.

Armaganijan L, Morillo CA. Treatment of vasovagal syncope: an update. Curr Treat Options Cardiovasc Med. 2010 Oct;12(5):472-88.

CURRENT-OASIS 7 Investigators, Mehta SR, Bassand JP, Chrolavicius S, Diaz R, Eikelboom JW, Fox KA, Granger CB, Jolly S, Joyner CD, Rupprecht HJ, Widimsky P, Afzal R, Pogue J, Yusuf S. Dose comparisons of clopidogrel and aspirin in acute coronary syndromes. N Engl J Med. 2010 Sep 2;363(10):930-42.

Armaganijan L, Morillo CA. Chagas disease: 101 years of solitude! Time for action. Stroke. 2010 Nov;41(11):2453-4. Epub 2010 Sep 23.

Menon SM, Healey JS, Morillo CA. Epsilon waves during ven-tricular tachycardia in a case of arrhythmogenic right ventricular dysplasia. Circulation. 2010 Oct 26;122(17):1752-5.

Divakara Menon SM, Healey JS, El Bayomy M, Morillo CA.Entrainment of supraventricular tachycardia: What is the mechanism? Heart Rhythm. Epub 2010 Nov 9.

Divakara Menon SM, Ribas CS, Ribas Meneclier CA, Morillo CA. Intermittent atrioventricular block: What is the mechanism? Heart Rhythm. Epub 2010 Nov 9.

Tang AS, Wells GA, Talajic M, Arnold MO, Sheldon R, Connolly S, Hohnloser SH, Nichol G, Birnie DH, Sapp JL, Yee R, Healey JS, Rouleau JL; Resynchronization-Defibrillation for Ambulatory Heart Failure Trial Investigators. Cardiac-resynchronization therapy for mild-to-moderate heart failure. N Engl J Med. 2010 Dec 16;363(25):2385-95. Epub 2010 Nov 14.

Ramírez JD, Guhl F, Rendón LM, Rosas F, Marin-Neto JA, Morillo CA. Chagas cardiomyopathy manifestations and Trypanosoma cruzi genotypes circulating in chronic Chagasic patients. PLoS Negl Trop Dis. 2010 Nov 30;4(11):e899.

Divakara Menon SM, Chemello D, Morillo CA. Sarcoidosis: yet another masquerader the cardiologist / electrophysiologist has to fight with. Indian Pacing Electrophysiol J. 2010 Dec 26;10(11):479-85.

NAIR, G.Tang AS, Wells GA, Talajic M, Arnold MO, Sheldon R, Connolly S, Hohnloser SH, Nichol G, Birnie DH, Sapp JL, Yee R, Healey JS, Rouleau JL; Resynchronization-Defibrillation for Ambulatory Heart Failure Trial Investigators (Collaborator). Cardiac-resynchroniza-tion therapy for mild-to-moderate heart failure. N Engl J Med. 2010 Dec 16;363(25):2385-95. Epub 2010 Nov 14.

Healey JS, Nair GM, Connolly SJ, Morillo CA. A Rare Cause of Implantable Cardioverter-Defibrillator Failure: Short-Circuiting via an Un-Used Pace-Sense Lead. Heart Rhythm. 2010 Nov;7(11):1630-1. Epub 2010 Jul 21.

Healey JS, Birnie DH, Lee DS, Krahn AD, Crystal E, Simpson CS, Dorian P, Chen Z, Cameron D, Verma A, Connolly SJ, Gula LJ, Lockwood E, Nair GM, Tu JV; on behalf of the Ontario ICD Database Investigators. Defibrillation Testing at the Time of ICD Insertion: An Analysis from the Ontario ICD Registry. J Cardiovasc Electrophysiol. 2010 Dec;21(12):1344-8.

Verma A, Mantovan R, Macle L, De Martino G, Chen J, Morillo CA, Novak P, Calzolari V, Guerra PG, Nair GM, Torrecilla EG, Khaykin Y. Substrate and Trigger Ablation for Reduction of Atrial Fibrillation (STAR AF): a randomized, multicentre, international trial. Eur Heart J. 2010 Jun;31(11):1344-56.

Nery PB, Fernandes R, Nair GM, Sumner GL, Ribas CS, Divakara Menon SM, Wang X, Krahn AD, Morillo CA, Connolly SJ, Healey JS. Device-Related Infection Among Patients With Pacemakers and Implantable Defibrillators: Incidence, Risk Factors, and Consequences. J Cardiovasc Electrophysiol. 2010 Jul;21(7):786-90.

Healey JS, Dorian P, Mitchell LB, Talajic M, Philippon F, Simpson C, Yee R, Morillo CA, Lamy A, Basta M, Birnie DH, Wang X, Nair GM, Crystal E, Kerr CR, Connolly SJ; CREDIT Investigators. Canadian Registry of ICD Implant Testing procedures (CREDIT): current practice, risks, and costs of intraoperative defibrillation testing. J Cardiovasc Electrophysiol. 2010 Feb;21(2):177-82. Epub 2009 Oct 5.

Verma A, Sanders P, Macle L, Champagne J, Nair GM, Calkins H, Wilber DJ. Selective CFAE Targeting for Atrial Fibrillation Study (SELECT AF): Clinical Rationale, Design, and Implementation. J Cardiovasc Electrophysiol. 2011 May;22(5):541-7. Epub 2010 Nov 18.

NESATHURAI, S.Mahadevappa K, Vora A, Graham A, Nesathurai S. Facial paralysis: A critical review of accepted Explanation. Med Hypotheses. 2010 Mar;74(3):508-9.

O’BYRNE, P.Kelly MM, O‘Connor TM, Leigh R, Otis J, Gwozd C, Gauvreau GM, Gauldie J, O‘Byrne PM. Effects of Budesonide/Formoterol on Allergen-Induced Airway Responses, Inflammation and Remodeling. J Allergy Clin Immunol. 2010;125:349-56.

Bateman ED, Reddel HK, Ericksson G, Peterson S, Ostlund O, O’Byrne PM. The relationship between current control and future risk. J Allergy Clin Immunol. 2010;125:600-8.

FitzGerald JM, O’Byrne PM, McFetridge JT, Demuth D, Allen-Ramey FC. Pulmonary function testing in the emergency depart-ment and medications prescribed at discharge: results of the Multinational Acute Asthma Management, Burden, and Outcomes (MAMBO) study. Prim Care Resp J. 2010;19:155-62.

Murphy DM, O’Byrne PM. Recent advances in the pathophysiology of asthma. Chest. 2010;37:1417-26.

O’Byrne PM, Reddel HK, Eriksson G, Peterson S, Sears MR, Jenkins C, Humbert M, Buhl R, Harrison TW, Quirce S, Bateman ED. Measuring asthma control: a comparison of three classifica-tion systems. Eur Respir J. 2010:36:269-76.

O’Byrne PM, Reddel HK, Colice GL. Does the current stepwise approach to asthma pharmacotherapy encourage over-treatment? Respirology. 2010;15:596-602.

O’Byrne PM. Airway hyperresponsiveness in asthma: its measure-ment and clinical significance. Chest. 2010;138:S1-S3.

Dua B, Watson RM, Gauvreau GM, O’Byrne PM. Myeloid and plas-macytoid dendritic cells in induced sputum after allergen inhala-tion in asthmatic subjects. J Allergy Clin Immunol. 2010;126:133-9.

Nair P, Kjarsgaard M, Armstrong S, Efthimiadis A, O’Byrne PM, Hargreave FE. Nitric oxide in exhaled breath is poorly correlated to sputum eosinophils in prednisone-dependent asthma. J Allergy Clin Immunol. 2010;126:404-6.

Bousquet J, Schunemann HJ, Zuberbier T, Baahert C, Baena-Cagnani C, Bousquet PJ, Brozek J, et al (including O’Byrne PM). Development and implementation of guidelines in allergic rhinitis – an ARIA-GA2LEN paper. Allergy. 2010;65:1212-21.

Rabinovitch N, Graber NJ, Chinchilli VM, Sorkness CA, Zeiger RS, Strunk RC, Bacharier LB, Martinez FD, Szefler SJ; Childhood Asthma Research and Education Network of the National Heart, Lung, and Blood Institute (including O’Byrne PM). Urinary leukot-riene E4/exhaled nitric oxide ratio and montelukast response in childhood asthma. J Allergy Clin Immunol. 2010;126:545-51.

MERTZ, D.Orasch C, Weisser M, Mertz D, Heim D, Christen S, Gratwohl A, Battegay M, Widmer AF, Flückiger U. Comparison of infectious complications during induction/consolidation chemotherapy versus allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant. 2010;45(3):521-6.

Mertz D, Frei R, Periat N, Scheidegger C, Hellstern P, Battegay M, Seiler W, Widmer AF. Eradication of an epidemic methicillin-resis-tance Staphylococcus aureus (MRSA) from a geriatric university hospital: Evidence from a >10 years follow-up. Eur J Clin Microbiol Infect Dis. 2010;29(8):987-93.

Mertz D, Frei R, Plagge H, Battegay M, Widmer AF. Stronger correlation between antibiotic consumption and incidence of Clostridium difficile determined by cultures instead of faecal toxin only. Eur J Clin Microbiol Infect Dis. 2010;29(12):1175-8.

Mertz D, Dafoe N, Walter SD, Brazil KL, Loeb M. Effect of a multi-faceted intervention on adherence to hand hygiene among healthcare workers: a cluster randomized trial. Infect Control Hosp Epidemiol. 2010;31(11):1170-6.

Mertz D, Plagge H, Bassetti S, Battegay M, Widmer AF. How much money can be saved by applying intravenous antibiotics once instead of several times a day? Infection. 2010;38(6):479-82.

MOAYYEDI, P.Moayyedi P, Ford AC, Talley NJ, Cremonini F, Foxx-Orenstein AE, Brandt L, Quigley EM. The efficacy of probiotics in the therapy of irritable bowel syndrome: a systematic review. Gut. 2010;59:325-32.

Marshall JK, Thabane M, Garg AX, Clark WF, Moayyedi P, Collins SM. Eight year prognosis of postinfectious irritable bowel syn-drome following waterborne bacterial dysentery. Gut. 2010;59:605-11.

Sreedharan A, Martin J, Leontiadis GI, Dorward S, Howden CW, Forman D, Moayyedi P. Proton pump inhibitor treatment initiated prior to endoscopic diagnosis in upper gastrointestinal bleeding. Cochrane Database Syst Rev. 2010;7:CD005415.

Gatta L, Moayyedi P, Tosetti C, Vakil N, Ubaldi E, Barsant P, Fiorini G, Castelli V, Gargiulo C, Lucarini P, Lera M, Kajo E, Di Mario F, Vaira D. A validation study of the Italian Short-Form Leeds Dyspepsia Questionnaire. Internal and Emergency Medicine. 2010;5:501-6.

Ford AC, Marwaha A, Lim A, Moayyedi P. What is the prevalence of clinically significant endoscopic finding in subjects with dys-pepsia? Systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2010;8:830-7.

Ford AC, Moayyedi P. Meta-analysis: factors affecting placebo response rate in irritable bowel syndrome. Aliment Pharmacol Ther. 2010;32:144-58.

Barkun AN, Bardou M, Kuipers EJ, Sung J, Hunt RH, Martel M, Sinclair P; International Consensus Upper Gastrointestinal Bleeding Conference Group. International consensus recommen-dations on the management of patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med. 2010;152:101-13.

Cameron C, VAN Zanten SV, Skedgel C, Flowerdew G, Moayyedi P, Sketris I. Cost-utility analysis of proton pump inhibitors and other gastro-protective agents for prevention of gastrointestinal compli-cations in elderly patients taking non-selective non-steroidal anti-inflammatory agents. Aliment Pharmacol Ther. 2010;31:1354-64.

Ford AC, Thabane M, Collins SM, Moayyedi P, Garg AX, Clark WF, Marshall JK. Prevalence of Uninvestigated Dyspepsia 8 Years After a Large Waterborne Outbreak of Bacterial Dysentery: Cohort Study. Gastroenterology. 2010;138:373-8.

Villani AC, Lemire M, Thabane M, Belisle A, Geneau G, Garg AX, Clark WF, Moayyedi P, Collins SM, Franchimont D, Marshall

JK. Genetic Risk Factors for Post-Infectious Irritable Bowel Syndrome Following a Waterborne Outbreak of Gastroenteritis. Gastroenterology. 2010;138:1502-13.

Luther J, Higgins PD, Schoenfeld PS, Moayyedi P, Vakil N, Chey WD. Empiric quadruple vs. triple therapy for primary treatment of Helicobacter pylori infection: Systematic review and meta-analysis of efficacy and tolerability. Am J Gastroenterol. 2010;105:65-73.

Ford AC, Guyatt GH, Talley NJ, Moayyedi P. Errors in the conduct of systematic reviews of pharmacological interventions for irritable bowel syndrome. Am J Gastroenterol. 2010;105:280-8.

Ford AC, Marwaha A, Lim A, Moayyedi P. Systematic Review and Meta-Analysis of the Prevalence of Irritable Bowel Syndrome in Individuals With Dyspepsia. Clin Gastroenterol Hepatol. 2010;8:401-9.

Laine L, Spiegel B, Rostom A, Moayyedi P, Kuipers EJ, Bardou M, Sung J, Barkun AN. Methodology for randomized trials of patients with nonvariceal upper gastrointestinal bleeding: recommenda-tions from an international consensus conference. American Journal of Gastroenterology. 2010;105:540-50.

Chey WD, Moayyedi P. Passing the Torch: The American Journal of Gastroenterology 2010. American Journal of Gastroenterology. 2010;105:4-7.

MOFFAT, K.Cuker A, Raby A, Moffat KA, Flynn G, Crowther MA. Interlaboratory variation in heparin monitoring: lessons from the Quality Management Program of Ontario coagulation surveys. Thrombosis and Heamostasis. 2010;104:837-44.

Hayward CPM, Moffat KA, Raby A, Israels S, Plumhoff E, Flynn G, Zehnder JL. Development of North American consensus guidelines for medical laboratories that perform and interpret platelet func-tion using light transmission aggregometry. American Journal of Clinical Pathology. 2010;134:955-63.

MORILLO, C.Healey JS, Dorian P, Mitchell LB, Talajic M, Philippon F, Simpson C, Yee R, Morillo CA, Lamy A, Basta M, Birnie DH, Wang X, Nair GM, Crystal E, Kerr CR, Connolly SJ; CREDIT Investigators. Canadian Registry of ICD Implant Testing procedures (CREDIT): current practice, risks, and costs of intraoperative defibrillation testing. J Cardiovasc Electrophysiol. 2010 Feb;21(2):177-82. Epub 2009 Oct 5.

Klemm HU, Krause KT, Ventura R, Schneider C, Aydin MA, Johnsen C, Boczor S, Meinertz T, Morillo CA, Kuck KH. Slow wall motion rather than electrical conduction delay underlies mechanical dys-synchrony in postinfarction patients with narrow QRS complex. J Cardiovasc Electrophysiol. 2010 Jan;21(1):70-7. Epub 2009 Sep 1.

Nery PB, Fernandes R, Nair GM, Sumner GL, Ribas CS, Menon SM, Wang X, Krahn AD, Morillo CA, Connolly SJ, Healey JS. Device-related infection among patients with pacemakers and implant-able defibrillators: incidence, risk factors, and consequences. J Cardiovasc Electrophysiol. 2010 Jul;21(7):786-90. Epub 2010 Jan 22.

Verma A, Mantovan R, Macle L, De Martino G, Chen J, Morillo CA, Novak P, Calzolari V, Guerra PG, Nair G, Torrecilla EG, Khaykin Y. Substrate and Trigger Ablation for Reduction of Atrial Fibrillation (STAR AF): a randomized, multicentre, international trial. Eur Heart J. 2010 Jun;31(11):1344-56. Epub 2010 Mar 9.

Pava LF, Perafán P, Badiel M, Arango JJ, Mont L, Morillo CA, Brugada J. R-wave peak time at DII: a new criterion for differen-tiating between wide complex QRS tachycardias. Heart Rhythm. 2010 Jul;7(7):922-6. Epub 2010 Mar 4.

Torres OA, Calzada JE, Beraún Y, Morillo CA, González A, González CI, Martín J. Role of the IFNG +874T/A polymorphism in Chagas disease in a Colombian population. Infect Genet Evol. 2010 Jul;10(5):682-5. Epub 2010 Mar 30.

142

PUBLICATIONS

WC, Ginsberg HN, Elam MB, Genuth S, Gerstein HC, Schubart U, Fine LJ. Effects of medical therapies on retinopathy progression in type 2 diabetes. N Engl J Med. 2010 Jul 15;363(3):233-44.

Ismail-Beigi F, Craven T, Banerji MA, Basile J, Calles J, Cohen RM, Cuddihy R, Cushman WC, Genuth S, Grimm RH Jr, Hamilton BP, Hoogwerf B, Karl D, Katz L, Krikorian A, O’Connor P, Pop-Busui R, Schubart U, Simmons D, Taylor H, Thomas A, Weiss D, Hramiak I; ACCORD trial group. Effect of intensive treatment of hyperglycae-mia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial. Lancet. 2010 Aug 7;376(9739):419-30.

RABBAT, C.Crowther MA, Cook DJ, Albert M, Williamson D, Meade M, Granton J, Skrobik Y, Langevin S, Mehta S, Hebert P, Guyatt GH, Geerts W, Rabbat C, Douketis J, Zytaruk N, Sheppard J, Greinacher A, Warkentin TE; Canadian Critical Care Trials Group. The 4Ts scoring system for heparin-induced thrombocytopenia in medical-surgical intensive care unit patients. J Crit Care. 2010 Jun;25(2):287-93.

Lau JH, Gangji AS, Rabbat CG, Brimble KS. Impact of haemoglo-bin and erythropoietin dose changes on mortality: a secondary analysis of results from a randomized anaemia management trial. Nephrol Dial Transplant. 2010 Dec;25(12):4002-9.

RASHID, S.Rashid S. Key Questions Resulting from the JUPITER Trial Assessing Cardiovascular Disease Intervention with Rosuvastatin. World Journal of Cardiology. 2010;1(1):41-5.

RATHBONE, M.Su CX, Picard P, Rathbone MP, and Jiang S. Guanosine-induced decrease in side population of lung cancer cells: lack of correla-tion with ABCG2 expression. J Biol Regul Homeost Agents. 2010 Jan-Mar;24(1):19-25.

RIBAS, C.S.Divakara Menon SM, Ribas CS, Ribas Meneclier CA, Morillo CA. Intermittent atrioventricular block: What is the mechanism? Heart Rhythm. Epub 2010 Nov 9.

Menon SM, Ribas CS, Hussein MH, Morillo CA. Case of long RP tachycardia responsive to adenosine: What is the mechanism? Heart Rhythm. Epub 2010 Sep 22.

Nery PB, Fernandes R, Nair GM, Sumner GL, Ribas CS, Menon SM, Wang X, Krahn AD, Morillo CA, Connolly SJ, Healey JS. Device-related infection among patients with pacemakers and implant-able defibrillators: incidence, risk factors, and consequences. J Cardiovasc Electrophysiol. 2010 Jul;21(7):786-90.

ROTSTEIN, C.Williamson DR, Albert M, Perreault MM, Delisle M, Muscedere J, Rotstein C, Jiang X, Heyland DK. The relationship between Candida species cultured from the respiratory tract and systemic inflamma-tion in critically ill patients with ventilator-associated pneumonia. Can J Anaesth. Epub 2010 Dec 14.

Bow EJ, Evans G, Fuller J, Laverdiere M, Rotstein C et al. Canadian clinical practice guidelines for invasive candidiasis in adults. Can J Infect Dis Med Microbiol. 2010;21:e122-e150.

Allen U, Bow E, Doyle J, Richardson S, Robinson J, Rotstein C, Davies D, Hui C, Le Saux N, Laverdiere M and Read S. Pediatric Antifungal Therapy – Part I: Focus on febrile neutropenia, inva-sive aspergillosis, combination antifungal therapy and invasive candidiasis in immunocompromised pediatric patients. Minerva Pediatrica. 2010;62(1):57-69.

Allen U, Bow E, Doyle J, Richardson S, Robinson J, Rotstein C, Davies D, Hui C, Le Saux N, Laverdiere M and Read S. Pediatric Antifungal Therapy – Part II: Neonatal infections. Minerva Pediatrica. 2010;62(1):72-8.

Patel M, Rotstein C. Echinocandins as first choice for invasive Candida infections in non-neutropenic patients. Neth J Crit Care. 2010;14:252-6.

SALEHIAN, O.Wright D, Salehian O. Brugada type electrocardiographic changes induced by chronic lithium use. Circulation. 2010;122:e418-9.

Tobler D, Fernandes SM, Landzberg M, Salehian O, Siu SC, Colman JM, Sermer M, Wald RM, Silversides CK. Pregnancy outcomes in women with transposition of great arteries and arterial switch operation. Am J Cardiol. 2010;106:417-20.

Kotchetkov R, Patel A, Salehian O. Ventricular tachycardia in preg-nant patients. A report of two cases. Clinical Med: Cardiol Insights. 2010;4:39-44.

Schwalm J-D, Ahmad M, Salehian O, Eikelboom JW, Natarajan MK. Warfarin after anterior myocardial infarction in current era of dual antiplatelet therapy: A randomized feasibility trial. J Thromb Thrombolysis. 2010 Aug;30(2):127-32.

Silversides CK, Marelli A, Beauchesne L, Dore A, Kiess M, Salehian O, Bradley T, Colman J, Connelly M, Harris L, Khairy P, Mital S, Niwa K, Oechslin E, Poirier N, Schwerzmann M, Taylor D, Vonder Muhll I, Baumgartner H, Benson L, Celermajer D, Greutmann M, Horlick E, Landzberg M, Meijboom F, Mulder B, Warnes C, Webb G, Therrien J. Canadian Cardiovascular Society 2009 Consensus Conference on the management of adults with congenital heart disease: Executive summary. Can J Cardiol. 2010;26:143-50.

Silversides CK, Salehian O, Oechslin E, Schwerzmann M, Vonder Muhll I, Khairy P, Horlick E, Landzberg M, Meijboom F, Warnes C, Therrien J. Canadian Cardiovascular Society 2009 Consensus Conference on the management of adults with congenital heart disease: Complex congenital cardiac lesions. Can J Cardiol. 2010;26:143-50.

SCHULMAN, S.Meijer K, Kim YK, Schulman S. Decreasing warfarin sensitivity dur-ing the first three months after heart valve surgery: Implications for dosing. Thromb Res. 2010;125:224-9.

Schulman S, Melinyshyn A, Ennis D, Rudd-Scott L. Single-dose adjustment versus no adjustment of warfarin in stably anticoagu-lated patients with an occasional level out of range. Thromb Res. 2010;125:393-7.

Kim YK, Nieuwlaat R, Connolly SJ, Schulman S, Meijer K, Raju N, Kaatz S, Eikelboom JW. Effect of a simple two-step warfarin dosing algorithm on anticoagulant control as measured by time-in-thera-peutic range: a pilot study. J Thromb Haemost. 2010;8:101-6.

Schulman S, Angerås U, Bergqvist D, Eriksson B, Lassen MR and Fisher W on behalf of the Subcommittee on Control of Anticoagulation of the Scientific and Standardization Committee of the International Soceity on Thrombosis and Haemostasis. Definition of major bleeding in clinical investigations of antihemo-static medicinal products in surgical patients. J Thromb Haemost. 2010;8:202-4.

Kristinsson SY, Pfeiffer RM, Björkholm M, Goldin LR, Schulman S, Blimark C, Mellqvist UH, Wahlin A, Turesson I, Landgren O. Arterial and venous thrombosis in monoclonal gammopathy of undeter-mined significance and multiple myeloma: a population-based study. Blood. 2010;115(24):4991-8.

Bousquet J, Mantzouranis E, Cruz AA, Ait-Khaled N, Baena-Cagnani C, Bleeker ER, et al (including O’Byrne PM) . Uniform defi-nition of asthma severity, control, and exacerbation: Documents presented for the World Health Organization Consultation on severe asthma. J Allergy Clin Immunol. 2010;126:926-38.

O’Byrne PM. Global guidelines for asthma management. Pol Arch Med Wewn. 2010;120:511-7.

PAPAIOANNOU, A.Giangregorio L, Thabane L, Cranney A, Adili A, deBeer J, Dolovich L, Adachi JD, Papaioannou A. Osteoporosis Knowledge among Individuals with a Recent Fragility Fracture. Orthop Nurs. 2010;29:99-107.

Sawka AM, Ismaila N, Cranney A, Thabane L, Kastner M, Gafni A, Woodhouse LJ, Crilly R, Cheung AM, Adachi JD, Josse RG, Papaioannou A. A Scoping Review of Strategies for the Prevention of Hip Fracture in Elderly Nursing Home Residents. PLoS ONE. 2010;5(3):e9515.

Jaglal SB, Hawker G, Cameron C, Canavan J, Beaton D, Bogoch E, Jain R, Papaioannou A; members of the Osteoporosis Research, Monitoring and Evaluation Working Group. The Ontario Osteoporosis Strategy: implementation of a population-based osteoporosis action plan in Canada. Osteoporosis Int. 2010 Jun;21(6):903-8.

Grima DT, Papaioannou A, Airia P, Ioannidis G, Adachi JD. Adverse events, bone mineral density and discontinuation associated with generic alendronate among postmenopausal women previously tolerant of brand alendronate: a retrospective cohort study. BMC Musculoskeletal Disorders. 2010;11:68.

Papaioannou A, Kennedy CC, Campbell G, Stroud J, Wang L, Dolovich L, Crowther MA and the Improving Prescribing in Long Term Care Investigators. A team-based approach to warfarin management in long term care: A feasibility study of the MEDeINR electronic decision support system. BMC Geriatrics. 2010;10:38.

Coker E, Papaioannou A, Kaasalainen S, Dolovich L, Turpie I, Taniguchi A. Nurses’ perceived barriers to optimal pain manage-ment in older adults on acute medical units. Appl Nurs Res. 2010 Aug;23(3):139-46.

Papaioannou A, Morin S, Cheung AM, Atkinson S, Brown JP, Feldman S, Hanley DA, Hodsman A, Jamal SA, Kaiser SM, Kvern B, Siminoski K, Leslie WD for the Scientific Advisory Council of Osteoposis Canada. 2010 clinical practic guidelines for the diagno-sis and management of osteoporosis in Canada: summary. CMAJ. 2010 Nov 23;182(17):1864-73. Epub 2010 Oct 12.

Lau AN, Ioannidis G, Potts Y, Giangregorio LM, Van der Horst ML, Adachi JD, Papaioannou A. What are the beliefs, attitudes and practices of front-line staff in long-term care (LTC) facilities related to osteoporosis awareness, management and fracture prevention? BMC Geriatrics. 2010;10:73.

Kaasalainen S, Brazil K, Coker E, Ploeg J, Martin-Misener R, Donald F, Dicenso A, Hadjistavropoulos T, Dolovich L, Papaioannou A, Emili A, Burns T. An action-based approach to improving pain management in long-term care. Can J Aging. 2010 Dec;29(4):503-17.

Fraser LA, Langsetmo L, Berger C, Ioannidis G, Goltzman D, Adachi JD, Papaioannou A, Josse R, Kovacs CS, Olszynski WP, Towheed T, Hanley DA, Kaiser SM, Prior J, Jamal S, Kreiger N, Brown JP, Johansson H, Oden A, McCloskey E, Kanis JA, Leslie WD; CaMos Research Group. Fracture prediction and calibration of a Canadian FRAX® tool: a population-based report from CaMos. Osteoporos Int. Epub 2010 Dec 16.

Jönsson B, & Ström O, Eisman JA, Papaioannou A, Siris ES, Tosteson A, Kanis JA. Cost-effectiveness of Denosumab for the treatment of postmenopausal osteoporosis. Osteoporos Int. Epub 2010 Oct 9.

Szabo KA, Webber CE, Gordon C, Adachi JD, Tozer R, Papaioannou A. Reproducibility of Peripheral Quantitative Computed Tomography Measurements at the Radius and Tibia in Healthy Pre- and Postmenopausal Women. Can Assoc Radiol J. Epub 2010 Jun 22.

Langsetmo L, Morin S, Kovacs CS, Kreiger N, Josse R, Adachi JD, Papaioannou A, Goltzman D, Hanley DA, Olszynski WP, Prior J, Jamal SA; CaMos Research Group. Determining whether women with osteopenic bone mineral density have low, moderate, or high clinical fracture risk. Menopause. 2010;17:1010-6.

Zhou W, Langsetmo L, Berger C, Adachi JD, Papaioannou A, Ioannidis G, Webber C, Atkinson SA, Olszynski WP, Brown JP, Hanley DA, Josse R, Kreiger N, Prior J, Kaiser S, Kirkland S, Goltzman D, Davison KS; CaMos Research Group. Normative bone mineral density z-scores for Canadians aged 16 to 24 years: the Canadian Multicenter Osteoporosis Study. J Clin Densitom. 2010;13:267-76.

Jager PL, Slart RH, Webber CL, Adachi JD, Papaioannou A, Gulenchyn KY. Combined vertebral fracture assessment and bone mineral density measurement: a patient-friendly new tool with an important impact on the Canadian Risk Fracture Classification. Can Assoc Radiol J. 2010;1:1-7.

Jamal SA, Swan VJ, Brown JP, Hanley DA, Prior JC, Papaioannou A, Langsetmo L, Josse RG; Canadian Multicentre Osteoporosis Study Research Group. Kidney function and rate of bone loss at the hip and spine: the Canadian Multicentre Osteoporosis Study. Am J Kidney Dis. 2010;55:291-9.

Kaasalainen S, Agarwal G, Dolovich L, Papaioannou A, Brazil K, Akhtar-Danesh N, Nurses’ Perceptions of and satisfaction with the medication administration system in long-term-care homes. CJNR. 2010;42(4):58-79.

Sawka AM, Ismaila N, Raina P, Straus S, Adachi JD, Gafni A, Papaioannou A. Hip fracture prevention strategies in long-term care A survey of Canadian physicians’ opinions. Can Fam Physician. 2010;56:e392-7.

PATEL, A.Abadir A, Patel A, Haider S. Systematic Therapy of New World Cutaneous Leishmaniasis: A case report and review article. Can J Infect Dis Med Microbiol. 2010;21(2):e79-e83.

Al-Saleh A, Patel A. Adult-Onset Still’s Disease Presenting as Fever of Unknown Origin. Can J Gen Int Med. 2010;5(2):66-7.

Abadir A, Patel A, Haider. Case Report and Review Article: Systemic therapy of New World Cutaneous Leishmaniasis. 2009-2010 Canadian Journal of Infectious Disease & Medical Microbiology (CJIDMM) Trainee Review Article Award. Can J Infect Dis Med Microbiol. 2010 Summer;21(2):e79-83.

PUNTHAKEE, Z.ACCORD Study Group, Cushman WC, Evans GW, Byington RP, Goff DC Jr, Grimm RH Jr, Cutler JA, Simons-Morton DG, Basile JN, Corson MA, Probstfield JL, Katz L, Peterson KA, Friedewald WT, Buse JB, Bigger JT, Gerstein HC, Ismail-Beigi F. Effects of intensive blood-pressure control in type 2 diabetes mellitus. N Engl J Med. 2010 Apr 29;362(17):1575-85. Epub 2010 Mar 14.

ACCORD Study Group, Ginsberg HN, Elam MB, Lovato LC, Crouse JR 3rd, Leiter LA, Linz P, Friedewald WT, Buse JB, Gerstein HC, Probstfield J, Grimm RH, Ismail-Beigi F, Bigger JT, Goff DC Jr, Cushman WC, Simons-Morton DG, Byington RP. Effects of combi-nation lipid therapy in type 2 diabetes mellitus. N Engl J Med. 2010 Apr 29;362(17):1563-74.

ACCORD Study Group; ACCORD Eye Study Group, Chew EY, Ambrosius WT, Davis MD, Danis RP, Gangaputra S, Greven CM, Hubbard L, Esser BA, Lovato JF, Perdue LH, Goff DC Jr, Cushman

144

PUBLICATIONS

SCHWALM, J-D.Schwalm JD, Ahmad M, Eikelboom JW, Natarajan MK. A National Survey of Canadian Practice Patterns of Warfarin after Anterior Wall Myocardial Infarction in the Current Era of Dual Antiplatelet Therapy. Am J Cardiol. 2010;105(12):1844.

Schwalm JD, Ahmad M, Salehian O, Eikelboom JW, Natarajan MK. Warfarin after anterior myocardial infarction in current era of dual antiplatelet therapy: A randomized feasibility trial. Journal of Thrombosis and Thrombolysis. 2010;30(2):127.

Jamula E, Lloyd NS, Schwalm JD, Airaksinen KE, Douketis JD. Safety of uninterrupted anticoagulation in patients requiring elec-tive coronary angiography with or without percutaneous coronary intervention: a systematic review and metaanalysis. Chest. 2010 Oct;138(4):840-7. Epub 2010 Apr 30.

Schwalm JD, Ahmad M, Velianou JL, Pericak D, Natarajan MK. Long-term Clinical Outcomes with Paclitaxel-Eluting Stents versus Bare Metal Stents in Everyday Practice. Canadian Journal of Cardiology. 2010;26(2):e40-e44.

Jamula E, Schwalm JD, Douketis JD. Periprocedural Anticoagulation Practices in Warfarin-treated Patients who require Elective Angiography with or without Percutaneous Coronary Intervention: A Retrospective Chart Review. Thrombosis Research. 2010 Apr;125(4):351-2.

SEARS, M.Hancox RJ, Poulton R, Ely M, Welch D, Taylor DR, McLachlan CR, Greene JM, Moffitt TE, Caspi A, Sears MR. Effects of cannabis on lung function: a population-based cohort study. Eur Respir J. 2010;35:42-7.

Asher MI, Stewart AW, Mallol J, Montefort S, Lai CK, Ait-Khaled N, Odhiambo J, ISAAC Phase One Study Group. Which population level environmental factors are associated with asthma, rhino-conjunctivitis and eczema? Review of the ecological analyses of ISAAC Phase One. Respir Res. 2010;11:8.

Bateman ED, Reddel HK, Eriksson G, Peterson S, Ostlund O, Sears MR, Jenkins C, Humbert M, Buhl R, Harrison TW, Quince S, O’Byrne PM. Overall asthma control: the relationship between cur-rent control and future risk. J Allergy Clin Immunol. 2010;125:600-8, 608.e1-608.e6.

O’Byrne PM, Reddel HK, Eriksson G, Ostlund O, Peterson S, Sears MR, Jenkins C, Humbert M, Buhl R, Harrison TW, Quince S, Bateman ED. Measuring asthma control: a comparison of three classification systems. Eur Respir J. 2010;36:269-76.

Weiss KB, Gern JE, Johnston NW, Sears MR, Jones CA, Jia G, Watkins MW, Smugar SS, Edelman JM, Grant EN. The Back to School asthma study: the effect of montelukast on asthma burden when initiated prophylactically at the start of the school year. Ann Allergy Asthma Immunol. 2010;105:174-81.

Andersen HR, Ruggles R, Pandey KD, Kapetanakis V, Brunekreef B, Lai CKW, Strachan DP, Weiland SK, the ISAAC Phase One Study Group. Ambient particulate pollution and the world-wide prevalence of asthma, rhinoconjunctivitis and eczema in children: Phase One of the International Study of Asthma and Allergies in Childhood (ISAAC). Occup Environ Med. 2010;67:293-300.

Chan-Yeung M, Anthonisen NR, Becklake MR, Bowie D, Sonia Buist A, Dimich-Ward H, Ernst P, Sears MR, Siersted HC, Sweet L, Van Til L, Manfreda J. Geographical variations in the prevalence of atopic sensitization in six study sites across Canada. Allergy. 2010;65:1404-13.

Wang H-Y, Pizzichini MMM, Becker AB, Duncan JM, Ferguson AC, Greene JM, Rennie DC, Senthilselvan A, Taylor BW, Sears MR. Disparate geographic prevalences of asthma, allergic rhinocon-junctivitis and atopic eczema among adolescents in 5 Canadian cities. Pediatr Allergy Immunol. 2010;21:867-77.

Kazani S, Ware JH, Drazen JM, Taylor DR, Sears MR. The safety of long-acting beta-agonists: more evidence is needed. Respirology. 2010;15:881-5.

SEBALDT, R.Haynes RB, Wilczynski N, Computerized Clinical Decision Support System (CCDSS) Systematic Review Team. Effects of computerized clinical decision support systems on practitioner performance and patient outcomes: Methods of a decision-maker-researcher part-nership systematic review. Implementation Science. 2010;5:12-9.

Tan JK, Tang J, Fung K, Gupta AK, Richard Thomas D, Sapra S, Lynde C, Poulin Y, Gulliver W, Sebaldt RJ. Development and valida-tion of a scale for acne scar severity (SCAR-S) of the face and trunk. J Cutan Med Surg. 2010;14:156-60.

SEHMI, R.Doyle TM, Ellis R, Park HJ, Inman MD, Sehmi R. Modulating pro-genitor accumulation attenuates lung angiogenesis in a mouse model of asthma. Eur Respir J. Epub 2010 Nov 11.

SHERBINO, J.Leblanc C, Sherbino J. Coaching in Emergency Medicine. Can J Emerg Med. 2010;12(6):520-4.

Sherbino J. Do Antiviral Medications Improve Recovery in Patients With Bell’s Palsy? Annals of Emergency Medicine. 2010;55(5):475-6.

Sherbino J. Does this patient have irritable bowel syndrome? Ann Emerg Med. 2010;(55):117-9.

Sherbino J, Keim SM, Davis DP. Clinical decision rules for termi-nation of resuscitation in out-of-hospital cardiac arrest. J Emerg Med. 2010 Jan;38(1):80-6.

Holmboe ES, Sherbino J, Long DM, Swing SR, Frank JR. The role of assessment in competency-based medical education. Med Teach. 2010;32(8):676-82.

Campbell C, Silver I, Sherbino J, Cate OT, Holmboe ES. Competency-based continuing professional development. Med Teach. 2010;32(8):657-62.

Iobst WF, Sherbino J, Cate OT, Richardson DL, Dath D, Swing SR, Harris P, Mungroo R, Holmboe ES, Frank JR. Competency-based medical education in postgraduate medical education. Med Teach. 2010;32(8):651-6.

Frank JR, Snell LS, Cate OT, Holmboe ES, Carraccio C, Swing SR, Harris P, Glasgow NJ, Campbell C, Dath D, Harden RM, Iobst W, Long DM, Mungroo R, Richardson DL, Sherbino J, Silver I, Taber S, Talbot M, Harris KA. Competency-based medical education: theory to practice. Med Teach. 2010;32(8):638-45.

Sherbino J. Education scholarship: the next step for our specialty. CJEM. 2010 Jul;12(4):347-8.

Healey A, Sherbino J, Fan J, Mensour M, Upadhye S, Wasi P. A low-fidelity simulation curriculum addresses needs identified by faculty and improves the comfort level of senior internal medicine resident physicians with in-hospital resuscitation. Crit Care Med. 2010 Sep;38(9):1899-903.

Carpenter C, Sherbino J. How does an “opinion leader” influence my practice? CJEM. 2010;12(5):431-4.

Sherbino J, Snell L, Dath D, Dojeji S, Abbott C, Frank JR. A National Clinician-Educator Program: A Model of an Effective Community of Practice. Med Educ Online. 2010 Dec 6;15.

SHETH, T.Sun JCJ, Teoh KHT, Lamy A, Sheth T, Ellins ML, Jung H, Anand S, Yusuf S, Connollly S, Eikelboom JW. Randomized trial of aspirin

Crowther MA, Garcia D, Ageno W, Wang L, Witt DM, Clark NP, Blostein MD, Kahn SR, Schulman S, Kovacs M, Rodger MA, Wells P, Anderson D, Ginsberg J, Selby R, Siragusa S, Silingardi M, Dowd MB, Kearon C. Oral vitamin K effectively treats INR values in excess of 10.0: Results of a prospective cohort study. Thromb Haemost. 2010;104(1):118-21.

Schulman S, Anderson DR, Bungard TJ, Jaeger T, Kahn SR, Wells P, Jo-Anne Wilson S. Direct and indirect costs of management of long-term warfarin therapy in Canada. J Thromb Haemost. Epub 2010 Jul 16.

Huisman MV, Quinlan DJ, Dahl OE, Schulman S. Enoxaparin versus dabigatran or rivaroxaban for thromboprophylaxis after hip or knee arthroplasty: results of separate pooled analyses of phase III mul-ticenter randomized trials. Circ Cardiovasc Qual Outcomes. Epub 2010 Oct 5.

Majeed A, Kim Y, Holmström M, Roberts RS, Schulman S. Optimal timing of resumption of warfarin after intracranial hemorrhage. Stroke. 2010;41:2860-6.

Schulman S and Spencer FA. Antithrombotic drugs in Coronary Artery Disease: Risk benefit ratio and bleeding. J Thromb Haemost. 2010;8:641-50.

Schulman S. New aspects on treatment modalities for thromboem-bolic episodes. J Intern Med. 2010;268:109-19.

SCHÜNEMANN, H.Akl EA, Pretorius RW, Sackett K, Erdley WS, Bhoopathi PS, Alfaarah Z, Schünemann HJ. The effect of educational games on medical students’ learning outcomes: a systematic review. BEME Guide No 14. Med Tech. 2010;32(1):16-27.

Schünemann HJ, Sperati F, Barba M, Santesso N, Melegari C, Akl EA, Guyatt G, Muti P. An instrument to assess quality of life in rela-tion to nutrition: item generation, item reduction and initial valida-tion. Health Qual Life Outcomes. 2010 Mar;11;8:26.

Akl EA, Gunukula S, Mustafa R, Wilson MC, Symons A, Moheet A, Schünemann HJ. Support for and aspects of use of educational games in family medicine and internal medicine residency pro-grams in the US: a survey. BMC Med Educ. 2010;10:26.

Alfarah Z, Schünemann HJ, Akl EA. Educational games in geriatric med-icine education: a systematic review. BMC Geriatr. 2010 Apr 23;10:19.

Carling CL, Kristoffersen DT, Oxman AD, Flottorp S, Fretheim A, Schünemann HJ, Akl EA, Herrin J, MacKenzie TD, Montori VM. The effect of how outcomes are framed on decisions about wheth-er to take antihypertensive medication: a randomized trial. PLoS One. 2010;1;5(3):e9469.

Schernhammer ES, Berrino F, Krogh V, Secreto G, Micheli A, Venturelli E, Grioni S, Sempos CT, Cavalleri A, Schünemann HJ, Strano S, Muti P. Urinary 6-Sulphatoxymelatonin levels and risk of breast cancer in premenopausal women: the ORDET cohort. Cancer Epidemiol Biomarkers Prev. 2010;19(3):729-37.

Bassler D, Briel M, Montori VM, Lane M, Glasziou P, Zhou Q, Heels-Ansdell D, Walter SD, Guyatt GH; STOPIT-2 Study Group. Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analy-sis. JAMA. 2010;303(12):1180-7.

Schünemann HJ, Hill S, Guyatt G, Akl E, Ahmed F. The GRADE approach and Bradford Hill’s criteria for causation. Journal of Epidemiology and Community Health. Epub 2010 October 14.

Raad D, Gaddam S, Schünemann HJ, Irani J, Abou Jaoude P, Honeine R, Akl EA. Effects of waterpipe tobacco smoking on lung function: a systematic review and meta-analysis. Chest. Epub 2010 Jul 29.

Ibargoyen-Roteta N, Gutiérrez-Ibarluzea I, Rico-Iturrioz R, López-Argumedo M, Reviriego-Rodrigo E, Cabriada-Nuño JL,

Schünemann HJ. The GRADE approach for assessing new tech-nologies as applied to apheresis devices in ulcerative colitis. Implement Sci. 2010 Jun 16;5:48.

Guyatt G, Akl EA, Hirsh J, Kearon C, Crowther M, Gutterman D, Lewis SZ, Nathanson I, Jaeschke R, Schünemann HJ. The vexing problem of guidelines and conflict of interest: a potential solution. Ann Intern Med. 2010;152(11):738-41.

Terracciano L, Brozek J, Compalati E, Schünemann HJ. GRADE system: new paradigm. Curr Opin Allergy Clin Immunol. 2010;10(4):377-83.

Charles LE, Burchfiel CM, Mnatsakanova A, Fekedulegn D Tinney-Zara C, Joseph PN, Schünemann HJ, Violanti JM, Andrew ME, Ochs-Balcom HM. Antioxidants and pulmonary function among police officers. Journal Occupational Environmental Medicine. 2010;52(11):1124-31.

Turner D, Schünemann HJ, Griffith LE, Beaton DE, Griffiths AM, Critch JN, Guyatt GH. The minimal detectable change cannot reli-ably replace the minimal important difference. J Clin Epidemiol. 2010;63(1):28-36.

Johnston BC, Thorlund K, Schünemann HJ, Xie F, Murad MH, Montori VM, Guyatt GH. Improving the interpretation of quality of life evidence in meta-analyses: the application of minimal impor-tant difference units. Health Qual Life Outcomes. 2010;11;8:116.

Bousquet J, Schünemann HJ, Zuberbier T, Bachert C, Baena-Cagnani CE, Bousquet PJ et al; In collaboration with the WHO Collaborating Center of Asthma and Rhinitis (Montpellier). Development and implementation of guidelines in allergic rhinitis – an ARIA-GA2LEN paper. Allergy. 2010; 65(10):1212-21.

Brozek JL, Bousquet J, Baena-Cagnani CE, Bonini S, Canonica GW, Casale TB, van Wijk RG, Ohta K, Zuberbier T, Schünemann HJ; Global Allergy and Asthma European Network; Grading of Recommendations Assessment, Development and Evaluation Working Group. Allergic Rhinitis and its impact on asthma (ARIA) guidelines: 2010 revision. J Allergy Clin Immunol. 2010 Sep;126(3):466-76.

Fiocchi A, Brozek J, Schünemann H, Bahna SL, von Berg A, Beyer K, Bozzola M, Bradsher J, Compalati E, Ebisawa M, Guzmán MA, Li H, Heine RG, Keith P, Lack G, Landi M, Martelli A, Rancé F, Sampson H, Stein A, Terracciano L, Vieths S; World Allergy Organization (WAO) Special Committee on Food Allergy. World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow’s Milk Allergy (DRACMA) Guidelines. Pediatr Allergy Immunol. 2010 Jul;21 Suppl 21:1-125.

Alonso-Coello, Schünemann HJ. The quality of clinical practice guidelines over the last two decades: a systematic review of guideline appraisal studies. Quality and Safety in Health Care. 2010 Dec;19(6)e:58.

Fiocchi A, Brozek J, Schünemann H, Bahna SL, von Berg A, Beyer K, Bozzola M, Bradsher J, Compalati E, Ebisawa M, Guzman MA, Li H, Heine RG, Keith P, Lack G, Landi M, Martelli A, Rancé F, Sampson H, Stein A, Terracciano L, Vieths S, World Allergy Organization (WAO). Diagnosis and Rationale for Action against Cow’s Milk Allergy (DRACMA) Guidelines. World Allergy Organization Journal. 2010 April;3(4):57-161.

Fiocchi A, Schünemann HJ, Brozek J, Restani P, Beyer K, Troncone R, Martelli A, Terracciano L, Bahna SL, Rancé F, Ebisawa M, Heine RG, Assa’ad A, Sampson H, Verduci E, Bouygue GR, Baena-Cagnani C, Canonica W, Lockey RF. Diagnosis and Rationale for Action Against Cow’s Milk Allergy (DRACMA): a summary report. J Allergy Clin Immunol. 2010 Dec;126(6):1119-28.

Akl EA, Vasireddi SR, Gunukula S, Yosuico VE, Barba M, Terrenato I, Sperati F, Schünemann H. Oral anticoagulation in patients with cancer who have no therapeutic or prophylactic indication for anticoagulation. Cochrane Database Syst Rev. 2010 Dec 8;(12):CD006466.

146

PUBLICATIONS

Humphries R, Griener TP, Vogt S, Mulvey G, Raivio T, Donnenberg MS, Kitov P, Surette MG, Armstrong GD. N-acetyllactosamine-induced retraction of EPEC bundle forming pili is a trigger for locus of enterocyte effacement gene down-regulation and BFP up-regu-lation. Mol Microbiol. 76: 1111-26.

Field TR, Sibley CD, Parkins MD, Rabin HR, Surette MG. The Genus Prevotella In Cystic Fibrosis Airways. Anaerobe. 2010 Aug;16(4):337-44. Epub 2010 Apr 20.

Grinwis ME, Sibley CD, Parkins MD, Eshaghurshan CS, Rabin HR and Surette MG. Macrolide and clindamycin resistance in Streptococcus milleri Group isolates from cystic fibrosis airways. Antimicrob Agents Chemother. 2010 Jul;54(7):2823-9. Epub 2010 Apr 19.

The Human Microbiome Jumpstart Reference Strains Consortium (contributing author). A Catalog of Reference Genomes from the Human Microbiome. Science. 2010 May 21;328(5981):994-9.

Sibley CD, Sibley KA, Leong TA, Grinwis ME, Parkins MD, Rabin HR, Surette MG. The Streptococcus milleri population of a cystic fibrosis clinic reveals patient specificity and intraspecies diversity. J Clin Microbiol. 2010 Jul;48(7):2592-4. Epub 2010 May 12.

Davidson CJ, Narang A, Surette MG. Integration of transcriptional inputs at promoters of the arabinose catabolic pathway. BMC Syst Biol. 2010 Jun 2;4:75.

Turnbull AL, Surette MG. Cysteine biosynthesis, oxidative stress and antibiotic resistance in Salmonella typhimurium. Res Microbiol. 2010 Oct;161(8):643-50. Epub 2010 Jun 25.

Chen L, Wang W, Sun W, Surette MG, Duan, K. Characterization of a cryptic plasmid from Pseudomonas sp. and utilization of its tem-perature-sensitive derivatives for genetic manipulation. Plasmid. 2010 Sep;64(2):110-7. Epub 2010 May 24.

White AP, Weljie AM, Apel D, Zhang P, Shaykhutdinov R, Vogel HJ, Surette MG. A global metabolic shift is linked to Salmonella multi-cellular development. PLoS One. 2010 Jul 27;5(7):e11814.

Sibley CD, Grinwis ME, Rabin HR, Surette MG. The Azithromycin Paradox in the Treatment of Cystic Fibrosis Airway Disease. Future Microbiol. 2010 Sep;5(9):1315-9.

Pilsczek FH, Salina D, Poon KK, Fahey C, Yipp BG, Sibley CD, Robbins SM, Green FH, Surette MG, Sugai M, Bowden MG, Hussain M, Zhang K, Kubes P. A Novel Mechanism of Rapid Nuclear Neutrophil Extracellular Trap Formation in Response to Staphylococcus aureus. J Immunol. 2010 Dec 15;185(12):7413-25. Epub 2010 Nov 22.

TANG, D.He L, Ingram A, Rybak AP, Tang D. Shank-interacting protein-like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells. J Clin Invest. 2010 Jun 1;120(6):2094-108. Epub 2010 May 10.

Wei F, Xie Y, Tao L, Tang D. Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation. Cell Signal. 2010 Nov;22(11):1783-9. Epub 2010 Jul 15.

TEO, K.Jassal DS, Bhagirath KM, Tam JW, Sochowski RA, Dumesnil JG, Giannoccaro PJ, Jue J, Pandey AS, Joyner CD, Teo KK, Chan KL. Association of bicuspid aortic valve morphology and aortic root dimensions: a substudy of the Aortic Stenosis Progressions Observation Measuring Effects of Rosuvastatin (ASTRONOMER) study. Echocardiography. 2010 Feb;27(2):174-9.

Chan KL, Teo K, Dumesnil JG, Ni A, Tam J for the ASTRONOMER Investigators. Effect of lipid lowering with rosuvastatin on progression of aortic stenosis. Results of the Aortic Stenosis

Progression Observation: Measuring Effects of Rosuvastatin (ASTRONOMER) Trial. Circulation. 2010;121:306-14.

Bohm M, Baumhakel M, Teo K, Sleight P, Probstfield J, Gao P, Mann JF, Diaz R, Dagenaais GR, Jennings GLR, Liu L, Jansky P, Yusuf S, for the ONTARGET/TRANSCEND ERECTILE Dysfunction Substudy Investigators. Erectile dysfunction predicts cardiovas-cular events in high-risk patients receiving telmisartan, ramipril or both. The Ongoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial/Telmisartan Randomized Assessment Study in ACE Intolerant subjects with cardiovascular Disease (ONTARGET/TRANSCEND) Trials. Circulation. 2010;121:1439-46.

Maron DJ, Boden WE, O’Rourke RA, Hartigan PM, Calfas KJ, Mancini GBJ, Spertus JA, Dada M, Kostuk WJ, Knudtson M, Harris CL, Sedlis SP, Zoble RG, Title LM, Nawaz S, Gau GT, Blaustein AS, Bates ER, Shaw LJ, Berman DS, Chaitman BR, Weintraub WS, Teo KK, for the COURGAGE Trial Researchers. Intensive multi-factorila intervention for stable coronary artery disease. Optimal Medical Therapy in the COURAGE (Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation) Trial. J Am Coll Cardiol. 2010;55:1348-58.

Bell KJL, Hayen A, Macaskill P, Craig JC, Neal BC, Fox KM, Remme WJ, Asselbergs FW, van Gilst WH, MacMahon S, Remuzzi G, Ruggenenti PR, Teo KK, Irwig L. Monitoring initial response to angiotensin-concerting enzyme inhibitor-based regimens. An indi-vidual patient meta-analysis from randomized placebo-controlled trials. Hypertension. 2010;56:533-9.

Chaitman BR, Hartigan PM, Booth DC, Teo KK, Mancini GBJ, Kostuk WJ, Spertus JA, Maron DJ, Dada M, O’Rourke RA, Weintraub WS, Berman DS, Shaw LJ, Boden WE, and on behalf of the Clinical Outcomes Utilizaing Revascularization and Aggressive Drug Evaluation (COURAGE) Trial Investigators. Do major car-diovascular outcomes in patients with stable ischemic heart disease in the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation Trial differ by healthcare system? Circ Cardiovasc Qual Outcomes. 2010;3:476-83.

Teo KK, Liang Y. Polypill: lights and shadows. Curr Hypertens Rep. 2010;12(10):276-81.

Mente A, Razak F, Blankenberg S, Vuksan V, Davis AD, Miller R, Teo K, Gerstein H, Sharma AM, Yusuf S, Anand SS. Study of the Health Assessment and Evaluation; Study of the Health Assessment and Risk Evaluation in Aboriginal Peoples Investigators. Ethnic variation in adipoectin and leptin levels and their association with adiposity and insulin resistance. Diabetes Care. 2010;33:1629-34.

Page A, Dumesnil JG, Clavel MA, Chan KL, Teo KK, Tam JW, Mathieu P, Despres JP, Pibarot P, ASTRONOMER Investigators. Metabloic syndrome is associated with more pronounced impairment of left ventricle geometry and function in patients with calcific aortic stenosis: a substudy of the ASTRONOMER (Aortic Stenosis Progression Observation Measuring Effects of Rosuvastatin) Study. J Am Coll Cardiol. 2010;27:55:1867-74.

Chow CK, Lock K, Madhavan M, Corsi DJ, Gilmore AB, Subramanian SV, Li W, Swaminathan S, Lopez-Jaramillo P, Avezum A, Lear SA, Dagenais G, Teo K, McKee M, Yusuf S. Environmental profile of a community’s health (EPOCH): an instrucment to mea-sure environmental determinants of cardiovascular health in five countries. PLoS ONE. 2010;5:e14294.

Dans AL, Teo K, Gao P, Chen JH, Kim JH, Yusoff K, Chaithiraphan S, Zhun J, Liu L, Yusuf S, for the ONTARGET investigators. In a sub-group of high risk Asians, telmisartan was non-inferior to ramipril and better tolerated in the prevention of cardiovascular events. PLoS ONE. 2010;5:e13694.

Lonn E, Bosch J, Teo KK, Pais P, Xavier D, Yusuf S. The polypill in the prevention of cardiovascular diseases: key concepts, current status, challenges, and future directions. Circulation. 2010;122:2078-88.

and clopidogrel versus aspirin alone for the prevention of coronary artery bypass graft occlusion. Am Heart J. 2010 Dec;160(6):1178-84.

Venkatesh V, Jain V, You J, Sheth T. Extra-cardiac Findings in Cardiac CT Angiography in Patients at Low to Intermediate Risk for Coronary Artery Disease. Can Assoc Rad J. 2010 Dec;61(5):286-90.

Chow B, Wells GA, Chen L, Yam Y, Beanlands RS, Abraham A, Dennie C, Sheth T, Ruddy TD. Prognostic Value of 64-slice Cardiac CT: Severity of Coronary Artery Disease, Coronary Atherosclerosis and Left Ventricular Ejection Fraction. J Am Coll Cardiol. 2010 Mar 9;55(10):1017-28.

Byrdie A, Chow B, Dennie CJ, Larose E, Leipsic JA, Sheth T, Gaham MM, Bulter G. Canadian Cardiovascular Society/Canadian Association of Radiologists Consensus Training Standards for Cardiac CT. Can J Cardiol. 2010 Apr;26(4):181-4.

SPENCER, F.Goldberg RJ, Spencer FA, Szklo-Coxe M, Tisminetzky M, Yarzebski J, Lessard D, Gore JM, Gaasch W. Symptom presentation in patients hospitalized with acute heart failure. Clinical Cardiol. 2010;33(6):E73-80.

Fornasini M, Yarzebski J, Chiriboga D, Lessard D, Spencer FA, Aurigemma P, Gore JM, Goldberg RJ. Contemporary Trends in Evidence-Based Treatment for Acute Myocardial Infarction. Am J Med. 2010;123(2):166-72.

Chan WS, Spencer FA, Ginsberg JS. A study in the anatomical dis-tribution of DVT in pregnancy. CMAJ. 182(7):657-60.

Chan WS, Lee A, Spencer FA, Chunilal S, Crowther M, Wu W, Johnston M, Rodger M, Ginsberg JS. D-Dimer Testing in Pregnant Patients: Towards Determining the Next “Level” in the Diagnosis of DVT. J Thromb Haemost. 2010;8(5):1004-11.

Schulman S, Spencer FA. Antithrombotic drugs in coronary artery disease: risk benefit ratio and bleeding. J Thromb Haemost. 2010;8(4):641-50.

Spencer FA, Montalescot G, Fox KAA, Goodman SG, Granger CB, Goldberg RJ, Oliveira GBF, Anderson FA, Eagle KA, FitzGerald G, Gore JM, and for the Global Registry of Acute Coronary Events (GRACE) Investigators. Delay to reperfusion in patients with acute myocardial infarction presenting to acute care hospitals. An inter-national perspective. Eur Heart J. 2010;31(11):1328-36.

Spencer FA, Goldberg RJ, Lessard D, Reed G, Emery C, Gore JM, Pacifico L, Weitz JI. Factors Associated with Adverse Outcomes in Outpatients Presenting with Pulmonary Embolism: The Worcester VTE Study. Circulation. 2010;3(4):390-4.

Nguyen HL, Goldberg RJ, Gore JM, Fox KAA, Eagle KA, Gurfinkel EP, Spencer FA, Reed G, Quill A, Anderson Jr FA. Age and Sex Differences, and Changing Trends, in the Use of Evidence-Based Therapies in Acute Coronary Syndromes: Perspectives from a Multinational Registry. Circ Cardiovasc Qual Outcomes. 2010;3(10):82-92.

Elbarouni B, Elmanfud O, Yan RT, Fox KAA, Kornder JM, Rose B, Spencer FA, Welsh RC, Wong GC, Goodman SG, Yan AT. Temporal Trend of In-hospital Major Bleeding Among Patients with Non St-elevation Acute Coronary Syndromes. Am Heart J. 2010;160:420-7.

Spencer FA, Bates SM, Goldberg RJ, Lessard D, Emery C, Glushchenko A, Gore JM, White RH. A Population-Based Study of Inferior Vena Caval Filters in Patients Diagnosed With Acute Venous Thromboembolism. Arch Intern Med. 2010;170:1456-62.

Nguyen HL, Gore JM, Saczynski JS, Yarzebski J, Reed G, Spencer FA, Goldberg RJ. Age and Sex Differences and 20-Year Trends (1986-2005) In Prehospital Delay In Patients Hospitalized with Acute Myocardial Infarction. Circ Cardiovasc Qual Outcomes. 2010;3:590-8.

SPYROPOULOS, A.Amin A, Spyropoulos AC, Dobesh P, Shorr A, Hussein M, Mozaffari E, Benner JS. Are hospitals delivering appropriate VTE prevention? The venous thromboembolism study to assess the rate of thrombo-prophylaxis (VTE START). J Thromb Thrombolysis. 2010;29(3):326-39.

Spyropoulos AC. To bridge or not to bridge, that is the question: the argument FOR bridging therapy in patients on oral anticoagulants requiring temporary interruption for elective procedures. J Thromb Thrombolysis. 2010 Feb;29(2):192-8.

Mahan CE, Spyropoulos AC. Venous thromboembolism preven-tion: A systematic review of methods to improve prophylaxis and decrease events in hospitalized patients. Hospital Practice. 2010;38(1):97-108.

Spyropoulos AC. Bridging therapy and oral anticoagulation: cur-rent and future prospects. Curr Opin Hematol. 2010;17(5):444-9.

Spyropoulos AC. Risk assessmennt of venous thromboembolism in hospitalized medical patients. Curr Opin Pulm Med. 2010;16(5):419-25.

STEINBERG, G.Dzamko N, van Denderen BJW, Hevener AL, Jørgensen SB, Honeyman J, Galic S, Chen ZP, Watt MJ, Campbell DJ, Steinberg GR and Kemp BE. AMPK β1 Deletion Reduces Appetite Preventing Obesity and Hepatic Insulin Resistance. J Biol Chem. 2010 Jan 1;285(1):115-22. Epub 2009 Nov 5.

Merry TL, Steinberg GR, Lynch GS, McConell GK. Skeletal muscle glucose uptake during contraction is regulated by nitric oxide and ROS independently of AMPK. Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E577-85. Epub 2009 Dec 15.

Galic S, Oakhill JS, Steinberg GR. Adipose tissue as an endocrine organ. Mol Cell Endocrinol. 2010 Mar 25;316(2):129-39. Epub 2009 Aug 31.

Fullerton MD and Steinberg GR. Sirt1 takes a backseat to AMPK in the regulation of insulin sensitivity by resveratrol. Diabetes. 2010 Mar;59(3):551-3.

Sachithanandan N, Fam BC, Fynch S, Dzamko N, Watt MJ, Wormald S, Honeyman J, Galic S, Proietto J, Andrikopoulos S, Hevener AL, Kay TW, Steinberg GR. Liver-specific suppressor of cytokine signaling-3 deletion in mice enhances hepatic insulin sensitivity and lipogenesis resulting in fatty liver and obesity. Hepatology. 2010 Nov;52(5):1632-42.

Steinberg GR, O’Neill HM, Dzamko NL, Galic S, Jørgensen SB, Honeyman J, Hewitt K, Chen ZP, Schertzer JD, Scott J, Koentgen F, Lynch GS, Watt MJ, vanDenderen BJW, Campbell DJ, Kemp BE. Whole-body deletion of AMPK β2 reduces muscle AMPK activity and exercise capacity. J Biol Chem. 2010 Nov 26;285(48):37198-209. Epub 2010 Sep 20.

SURETTE, M.Grinwis ME, Sibley CD, Parkins MD, Eshaghurshan CS, Rabin, HR, Surette MG. Characterization of Streptococcus milleri Group Isolates from Expectorated Sputum of Adult Cystic Fibrosis Patients. J Clin Microbiol. 2010 Feb;48(2):395-401. Epub 2009 Dec 9.

Sibley CD, Grinwis ME, Field TR, Parkins MD, Norgaard JC, Gregson DB, Rabin HR, Surette MG. McKay Agar Enables Routine Quantification of the Streptococcus milleri Group in Cystic Fibrosis Patients. J Med Microbiol. 2010 May;59(Pt 5):534-40. Epub 2010 Jan 21.

Olson AB, Sibley CD, Schmidt L, Wilcox MA, Surette MG Corbett CR. Development of real-time PCR assays for detection of the Streptococcus milleri Group from Cystic fibrosis clinical specimens using targets for cpn60 and 16s rRNA genes. J Clin Microbiol. 2010 Apr;48(4):1150-60. Epub 2010 Feb 17.

148

PUBLICATIONS

Garnier D, Milsom C, Magnus N, Meehan B, Weitz J, Yu J, Rak J. Role of the tissue factor pathway in the biology of tumor initiating cells. Thromb Res. 2010 Apr;125 Suppl 2:S44-50.

Eikelboom JW, Weitz JI. New anticoagulants. Circulation. 2010 Apr 6;121(13):1523-32.

Spencer FA, Goldberg RJ, Lessard D, Reed G, Emery C, Gore JM, Pacifico L, Weitz JI. Factors associated with adverse outcomes in outpatients presenting with pulmonary embolism: The Worcester Venous Thromboemoblism Study. Circ Cardiovasc Qual Outcomes. 2010 Jul;3(4):390-4.

Al-Hashimi A, Caldwell J, Gonzalez-Gronow M, Pizzo SV, Aboumrad D, Pozza L, Al-Bayati H, Weitz JI, Stafford A, Chan H, Kapoor A, Dickhout JG, Austin RC. Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores. J Biol Chem. 2010 Sep 10;285(37):28912-23.

Raskob G, Cohen AT, Eriksson BI, Puskas D, Shi M, Bocanegra T, Weitz JI. Oral direct factor Xa inhibition with edoxaban for thromboprophylaxis after elective hip replacement: A random-ized double-blind dose-response study. Thromb Haemost. 2010 Sep;104(3):642-9.

Weitz J, Connolly SJ, Patel I, Salazar D, Rohatagi S, Mendell J, Kastrissios H, Jin J, Kunitada S. Randomized, parallel-group, multi-center, multinational phase 2 study of edoxaban, an oral factor Xa inhibitor, and warfarin for stroke prevention in patients with atrial fibrillation. Thromb Haemost. 2010 Sep;104(3):633-41.

Linkins LA, Weitz JI. New and emerging anticoagulant therapies for venous thromboembolism. Curr Treat Options Cardiovasc Med. 2010 Apr;12(2):142-55.

FUTURA/OASIS-8 Trial Group, Steg PG, Jolly SS, Mehta SR, Afzal R, Xavier D, Rupprecht HJ, Lopez-Sendon J, Diaz R, Avezum A, Widimsky P, Rao SV, Chrolavicius S, Meeks B, Joyner C, Pogue J, Yusuf S. Low-dose vs standard-dose unfractionated heparin for percutaneous coronary intervention in acute coronary syndromes treated with fondaparinux: the FUTURA/OASIS-8 randomized trial. JAMA. 2010 Sep 22;304(12):1339-49.

Anderson JAM, Weitz JI. Hypercoagulable states. Clin Chest Med. 2010 Dec;31(4):659-73.

Weitz JI, Cao C, Eriksson BI, Fisher W, Kupfer S, Raskob G, Spaeder J, Turpie AGG. A dose-finding study with TAK-442, an oral factor Xa inhibitor, in patients undergoing elective total knee replacement surgery. Thromb Haemost. 2010 Dec;104(6):1150-7.

Bowersox SS, Canafax D, Druzgala P, Milner P, Weitz JI. Antithrombotic activity of the novel oral anticoagulant, tecarfarin [Sodium 3-[4-((1,1,1,3,3,3,-hexafluoro-2-methylpropan-2-yloxy) carbonyl) benzyl]-2-oxo-2H-chromen-4-olate] in animal models. Thromb Res. 2010 Nov;126(5):e383-8.

Lindhoff-Last E, Samama MM, Ortel TL, Weitz JI, Spiro TE. Assays for measuring rivaroxaban: Their suitability and limitations. Ther Drug Monit. 2010 Dec;32(6):673-9.

Klement P, Berry L, Liao P, Wood H, Tressel P, Smith LJ, Haque N, Weitz JI, Hirsh J, Paredes N, Chan AKC. Antithrombin-heparin covalent complex reduces microemboli during cardiopulmonary bypass in a pig model. Blood. 2010 Dec 16;116(25):5716-23.

WELSFORD, M.O’Connor RE, Bossaert L, Arntz HR, Brooks SC, Diercks D, Feitosa-Filho G, Nolan JP, Vander Hoek TL, Walters DL, Wong A, Welsford M, Woolfrey K, on behalf of the Acute Coronary Syndrome Chapter Collaborators. Part 9: acute coronary syndromes: 2010 International consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recom-mendations. Circulation. 2010;122(suppl 2):S422-S465.

Bossaert L, O’Connor RE, Arntz HR, Brooks SC, Diercks D, Feitosa-Filho G, Nolan JP, Vander Hoek TL, Walters DL, Wong A, Welsford M, Woolfrey K, on behalf of the Acute Coronary Syndrome Chapter Collaborators. Part 9: acute coronary syndromes: 2010 International consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recom-mendations. Resuscitation. 2010;Suppl 1:e175-212.

Kollek D, Welsford M, Wanger K. Canadian operational and emotional prehospital readiness for a tactical violence event. Prehospital & Disaster Medicine. 2010;25(2):162-7.

Mercuri M, Velianou JL, Welsford M, Gauthier L, Natarajan MK. Improving the timeliness of care for patients with acute ST-eleva-tion myocardial infarction: Implications of “self-transport” versus use of EMS. Healthcare Quarterly. 2010;13(1):105-9.

WERSTUCK, G.McAlpine C, Bowes AJ, Werstuck GH. The role of glycogen synthase kinase (GSK)-3 in atherosclerosis. Curr Drug Targets. 2010;10:151-7.

Sage AT, Walter LA, Shi YY, Khan MI, Kaneto H, Capretta A, Werstuck GH. Hexosamine biosynthesis pathway (HBP) flux promotes endoplasmic reticulum (ER) stress, lipid accumulation, and inflammatory gene expression in hepatic cells. Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E499-511. Epub 2009 Dec 1.

Barra NG, Reid S, MacKenzie R, Werstuck GH, Trigatti BL, Richards C, Holloway AC, Ashkar AA. Interleukin-15 contributes to regulation of adipose tissue independent of food intake. Obesity. 2010;18:1601-9.

WILLIAMS, D.J.Williams DJ. Increased Myoepithelial Cells of Bronchial Submucosal Glands in Fatal Asthma. Thorax. 2010;65:32-8.

WORSTER, A.Worster A, Chan T. The role of glycogen synthase kinase (GSK)-3 in atherosclerosis? Ann Emerg Med. Epub 2010 Oct 16.

Chan T, Worster A. The Clinical Diagnosis of Arrhythmias in Patients Presenting With Palpitations. Ann Emerg Med. Epub 2010 Oct 12.

Worster A. Evidence-Based Emergency Medicine Clinical Synopsis. Ann Emerg Med. Epub 2010 Jun 18.

Varenbut M, Plater-Zyberk C, Worster A, Daiter J. Does Low Urine Creatinine Level Indicate the Presence of Urine Alcohol in Methadone Maintenance Treatment Patients? Am J of Drug and Alc Abuse. 2010;36(4):199-201.

Worster A, Keim SM, Sahsi R, Pancioli AM; Best Evidence in Emergency Medicine (BEEM) Group. Do either corticosteroids or antiviral agents reduce the risk of long-term facial paresis in patients with new-onset Bell’s palsy? J Emerg Med. 2010;38(4):518-23.

Kavsak PA, Worster A, You JJ, Oremus M, Elsharif A, Hill SA, Devereaux PJ, Macrae AR, Jaffe AS. Identification of myocardial injury in the emergency setting. Clin Biochem. 2010;43:539-44.

YOU, J.Kavsak P, Worster A, You JJ, Oremus M, Elsharif A, Hill S, Devereaux PJ, MacRae A, Jaffe A, Identification of myocardial injury in the emergency setting. Clin Biochem. 2010;43:539-44.

Venkatesh V, You JJ, Landry DJ, Ellins ML, Sheth T. Extra-cardiac findings in cardiac CT a-angiography in patients at low to inter-

UPADHYE, S.Healey A, Sherbino J, Fan J, Upadhye S, et al. A low-fidelity simulation curriculum addresses needs identified by faculty and improves the comfort level of senior internal medicine resident physicians with inhospital resuscitation. Crit Care Med. 2010 Sept;38(9):1899-903.

VALANI, R.Valani R, Cornacchia M, Kube D. Flight Diversions due to On-board Medical Emergencies on an International Commercial Airline. Aviat Space Environ Med. 2010;81:1037-40.

Valani R, Yanchar N, Grant V, Hancock BJ. The Development of a National Pediatric Trauma Curriculum. Medical Teacher. 2010;32(3):e115-e119.

VERDU, E.Lussier CR, Brial F, Roy SA, Langlois MJ, Verdu EF, Rivard N, Perreault N, Boudreau F. Loss of hepatocyte-nuclear-factor-1alpha impacts on adult mouse intestinal epithelial cell growth and cell lineages differentiation. PLoS One. 2010 Aug 24;5(8):e12378.

Bercik P, Verdu EF, Foster JA, Macri J, Potter M, Huang X, Malinowski P, Jackson W, Blennerhassett P, Neufeld KA, Lu J, Khan WI, Corthesy-Theulaz I, Cherbut C, Bergonzelli GE, Collins SM. Chronic gastrointestinal inflammation induces anxiety-like behavior and alters central nervous system biochemistry. Gastroenterology. 2010 Dec;139(6):2102-2112.e1.

VERHOVSEK, M.Verhovsek M, Henderson MPA, Cox G, Luo HY, Steinberg MH, Chui DHK. Unexpectedly low pulse oximetry measurements associated with variant hemoglobins: A systematic review, American Journal of Hematology. 2010;85(11):882-5.

WALKER, I.Stonebraker JS, Bolto-Maggs PHB, Soucie JM, Walker I, Brooker, M. A study of variations in the reported haemophilia A prevalence around the world. Haemophilia. 2010 Jan;16(1):20-32.

WALLACE, J.Vong L, Ferraz JGP, Panaccione R, Beck PL, Wallace JL. A pro-resolution mediator, prostaglandin D2, is specifically up-regulated in individuals in long-term remission from ulcerative colitis. Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):12023-7.

Wallace JL. Physiological and pathophysiological roles of hydro-gen sulfide in the gastrointestinal tract. Antioxid Redox Signal. 2010 May 1;12(9):1125-33.

Wallace JL, Caliendo G, Santagada V, Cirino G. Markedly reduced toxicity of a hydrogen sulfide-releasing derivative of naproxen (ATB-346). Br J Pharmacol. 2010 Mar;159(6):1236-46.

Ekundi-Valentin E, Santos K, Camargo E, Denadai-Souze A, Teixeira S, Grant A, Wallace JL, Muscara M, Costa S. Differing effects of exogenous and endogenous hydrogen sulfide in carrageenan-induced knee joint arthritis in the rat. Br J Pharmacol. 159:1463-74.

Martin GR, McKnight GW, Dicay M, Coffin CS, Ferraz JG, Wallace JL. Hydrogen sulfide synthesis in the rat and mouse gastrointesti-nal tract. Dig Liver Dis. 2010 Feb;42(2):103-9.

Caliendo C, Cirino G, Santagada V, Wallace JL. Synthesis and biological effects of H2S: development of H2S-releasing drugs as pharmaceuticals. J Med Chem. 2010 Sep 9;53(17):6275-86.

Wallace JL, Ferraz JGP. New pharmacologic therapies in gastroin-testinal disease. Gastroenterol Clin North Am. 2010 Sep;39(3):709-20.

WASERMAN, S.Fernandes JR, Wasserman S, Snider DP. Stimulation of anti-polio and anti-HSV IgA pre-plasma cell response in blood following parenteral immunization with tetanus-diphtheria vaccine. Vaccine. 2010 Feb 10;28(6):1493-8.

Kastner M, Harada L, Waserman S. Gaps in anaphylaxis manage-ment at the level of physicians, patients, and the community: a systematic review of the literature. Allergy. 2010 Apr;65(4):435-44.

Waserman S, Chad Z, Francoeur MJ, Small P, Stark D, Vander Leek TK, Kaplan A, Kastner M. Management of anaphylaxis in primary care: Canadian expert consensus recommendations. Allergy. 2010;65:1082–92.

Sheth SS, Waserman S, Kagan R, Alizadehfar R, Primeau MN, Elliot S, St Pierre Y, Wickett R, Joseph L, Harada L, Dufresne C, Allen M, Allen M, Godefroy SB, Clarke AE. Role of food labels in accidental exposures in food-allergic individuals in Canada. Ann Allergy Asthma Immunol. 2010 Jan;104(1):60-5.

Xu Y, Waserman S, Waserman S, Connors L, Stawiarski K, Kastner M. Food allergy management from the perspective of patients or caregivers, and allergists: a qualitative study. Allergy Asthma Clin Immunol. 2010 Nov 30;6(1):30.

WASI, P.Healy A, Sherbino J, Fan J, Mensour M, Upadhye S, Wasi P. A low-fidelity simulation curriculum addresses needs identified by faculty and improves the comfort level of senior internal medicine resident physicians with in-hospital resuscitation. Critical Care Medicine. 2010;38(9):1899-903.

WEITZ, J.Weitz DS, Weitz JI. Update on heparin: what do we need to know? J Thromb Thrombolysis. 2010 Feb;29(2):199-207.

Eikelboom JW, Weitz JI. Another oral thrombin inhibitor for stroke prevention in atrial fibrillation. Thromb Haemost. 2010 Mar;103(3):481-3.

Kretz CA, Cuddy KK, Stafford AR, Fredenburgh JC, Weitz JI. HD1, a thrombin- and prothrombin-binding DNA aptamer, inhibits thrombin generation by attenuating prothrombin activation and thrombin feedback reactions. Thromb Haemost. 2010 Jan;103(1):83-93.

Weitz JI. New oral anticoagulants in development. Thromb Haemost. 2010 Jan;103(1):62-70.

Weitz JI. Potential of new anticoagulants in patients with cancer. Thromb Res. 2010 Apr;125 Suppl 2:S30-5.

Eikelboom JW, Weitz JI. Update on antithrombotic therapy: New anticoagulants. Circulation. 2010;121:1523-32.

Lassen MR, Raskob GE, Gallus A, Pineo G, Chen D, Hornick P; ADVANCE 2 Investigators. Apixaban versus enoxaparin for throm-boprophylaxis after knee replacement (ADVANCE-2): A randomised double-blind trial. Lancet. 2010;375(9717):807-15. (Dr. Weitz was a member of the Independent Central Adjudication Committee).

Lassen MR, Gallus A, Raskob GE, Pineo G, Chen D, Ramirez LM; ADVANCE 3 Investigators. Apixaban versus enoxaparin for throm-boprophylaxis after hip replacement. New England Journal of Medicine. 2010;363(26):2487-98. (Dr. Weitz was a member of the Adjudication Committee).

Weitz JI. Meeting the unmet needs in anticoagulant therapy. Eur J Haematol. 2010 Jul;85 Suppl 72:p1-28.

150

PUBLICATIONS

cell function in people with impaired glucose tolerance or impaired fasting glucose: the DREAM trial. Diabetes Care. 2010;33(3):608-13.

Eikelboom JW, O’Donnell M, Yusuf S, Diaz R, Flaker G, Hart R, Hohnloser S, Joyner C, Lawrence J, Pais P, Pogue J, Synhorst D, Connolly SJ. Rationale and design of AVERROES: apixaban versus acetylsalicyclic acid to prevent stroke in atrial fibrillation patients who have failed or are unsuitable for vitamin K antagonist treat-ment. Am Heart J. 2010;159(3):348-53.

Bath PM, Cotton D, Martin RH, Palesch Y, Yusuf S, Sacco R, Diener HC, Estol C, Roberts R; PRoFESS Study Group. Effect of combined aspirin and extended-release dipyridamole versus clopidogrel on functional outcome and recurrence in acute mild ischemic stroke: PRoFESS subgroup analysis. Stroke. 2010;41(4):732-8.

Lanktree MB, Johansen CT, Anand SS, Davis AD, Miller R, Yusuf S, Hegele RA. Genetic variation in hyaluronan metabolism loci is associated with plasma plasminogen activator inhibitor-1 concen-tration. Blood. Epub 2010 June 17.

O’Donnell MJ, Xavier D, Lisheng L, Zhang H, Chin SL, Rao-Melacini P, Rangarajan S, Islam S, Pais P, McQueen MJ, Mondo C, Demasceno A, Lopez-Jaramillo P, Hankey GJ, Dans T, Yusoff K, Truelsen T, Diener HC, Sacco RL, Ryglewicz D, Czlonkowska A, Weimar C, Yusuf S on behalf of the INTERSTROKE investigators. Risk factors for ischaemic and haemorrhagic stroke in 22 coun-tries: results of the first phase of INTERSTROKE in 6,000 individu-als. Lancet. 2010;376(9735):112-23. Epub 2010 Jun 17.

ACCORD Study Group; ACCORD Eye Study Group, Chew EY, Ambrosius WT, Davis MD, Danis RP, Gangaputra S, Greven CM, Hubbard L, Esser BA, Lovato JF, Perdue LH, Goff DC Jr, Cushman WC, Ginsberg HN, Elam MB, Genuth S, Gerstein HC, Schubart U, Fine LJ. Effects of medical therapies on retinopathy progression in type 2 diabetes. N Engl J Med. 2010;363(3):233-44.

Yusuf S, Anand S. Deciphering the causes of cardiovascular and other complex diseases in populations: achievements, challenges, opportunities and approaches. Prog Cardiovasc Dis. 2010;53(1):62-7.

Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S; on behalf of the DREAM Investigators. Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Diabetes Care. Epub 2010 July 13.

Johansen CT, Wang J, Lanktree MB, Cao H, McIntyre AD, Ban MR, Martins RA, Kennedy BA, Hassell RG, Visser ME, Schwartz SM, Voight BF, Elosua R, Salomaa V, O’Donnell CJ, Dallinga-Thie GM, Anand SS, Yusuf S, Huff MW, Kathiresan S, Hegele RA. Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia. Nat Genet. 2010;42(8):684-7.

Anand SS, Yusuf S. C-reactive protein is a bystander of cardiovas-cular disease. Eur Heart J. Epub 2010 Jul 30.

De Caterina R, Connolly SJ, Pogue J, Chrolavicius S, Budaj A, Morais J, Renda G, Yusuf S on behalf of the ACTIVE Investigators. Mortality predictors and effects of antithrombotic therapies in atrial fibrillation: insights from ACTIVE-W. Eur Heart J. 2010;31(17):2133-40.

Gerstein HC, Islam S, Anand S, Almahmeed W, Damasceno A, Dans A, Lang CC, Luna MA, McQueen M, Rangarajan S, Rosengren A, Wang X, Yusuf S. Dysglycaemia and the risk of acute myocardial infarction in multiple ethnic groups: an analysis of 15,780 patients from the INTERHEART study. Diabetologia. Epub 2010 Aug 14.

Wallentin L, Yusuf S, Ezekowitz MD, Alings M, Flather M, Franzosi MG, Pais P, Dans A, Eikelboom J, Oldgren J, Pogue J, Reilly PA, Yang S, Connolly SJ; RE-LY investigators. Efficacy and safety of dabigatran compared with warfarin at different levels of interna-tional normalised ratio control for stroke prevention in atrial fibril-lation: an analysis of the RE-LY trial. Lancet. 2010;376(9745):975-83.

FUTURA/OASIS-8 Trial Group, Steg PG, Jolly SS, Mehta SR, Afzal R, Xavier D, Rupprecht HJ, López-Sendón JL, Budaj A, Diaz R,

Avezum A, Widimsky P, Rao SV, Chrolavicius S, Meeks B, Joyner C, Pogue J, Yusuf S. Low-dose vs standard-dose unfractionated heparin for percutaneous coronary intervention in acute coronary syndromes treated with fondaparinux: the FUTURA/OASIS-8 ran-domized trial. JAMA. 2010;304(12):1339-49.

Mehta SR, Tanguay JF, Eikelboom JW, Jolly SS, Joyner CD, Granger CB, Faxon DP, Rupprecht HJ, Budaj A, Avezum A, Widimsky P, Steg PG, Bassand JP, Montalescot G, Macaya C, Di Pasquale G, Niemela K, Ajani AE, White HD, Chrolavicius S, Gao P, Fox KA, Yusuf S; CURRENT-OASIS 7 trial investigators. Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial. Lancet. 2010;376(9748):1233-43.

CURRENT-OASIS 7 Investigators, Mehta SR, Bassand JP, Chrolavicius S, Diaz R, Eikelboom JW, Fox KA, Granger CB, Jolly S, Joyner CD, Rupprecht HJ, Widimsky P, Afzal R, Pogue J, Yusuf S. Dose comparisons of clopidogrel and aspirin in acute coronary syndromes. N Engl J Med. 2010 Sep 2;363(10):930-42. Erratum in: N Engl J Med. 2010 Oct 14;363(16):1585.

Do R, Bailey SD, Paré G, Montpetit A, Desbiens K, Hudson TJ, Yusuf S, Bouchard C, Gaudet D, Pérusse L, Anand S, Vohl MC, Pastinen T, Engert J. Fine Mapping of the INSIG2 Gene Identifies a Variant Associated with Low-Density Lipoprotein Cholesterol and Total ApoB Levels. Circ Cardiovasc Genet. Epub 2010 Sep 21.

Boyko EJ, Gerstein HC, Mohan V, Yusuf S, Sheridan P, Anand S, Shaw JE; for the DREAM trial investigators. Effects of ethnicity on diabetes incidence and prevention: results of the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) trial. Diabet Med. 2010;27(11):1226-32.

Cairns JA, Yusuf S, Cook RJ, Cox J, Dagenais GR, Devereaux PJ, McAlister FA, McCready T on behalf of CANNeCTIN. CANadian Network and Centre for Trials Internationally (CANNeCTIN): a national network for Canadian-led trials in cardiovascular diseases and diabetes mellitus. Can J Cardiol. 2010;26(7):353-8.

Clarke R, Halsey J, Lewington S, Lonn E, Armitage J, Manson JE, Bonaa KH, Spence JD, Nygard O, Jamison R, Gaziano JM, Guarino P, Bennett D, Mir F, Peto R, Collins R; B-Vitamin Treatmetn Trialists Collaboration. Effects of lowering homocystine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality: meta-analysis of 8 randomized trials involving 37 485 individuals. Arch Int Med. 2010;170(18):1622-31.

Paré G, Mehta SR, Yusuf S, Anand SS, Connolly SJ, Hirsh J, Simonsen K, Bhatt DL, Fox KA, Eikelboom JW. Effects of CYP2C19 genotype on outcomes of clopidogrel treatment. N Engl J Med 2010;363(18):1704-14.

Anderson C, Teo K, Gao P, Arima H, Dans A, Unger T, Commerford P, Dyal L, Schumacher H, Pogue J, Paolasso E, Holwerda N, Chazova I, Binbrek A, Young J, Yusuf S; for the ONTARGET and TRANSCEND Investigators. Renin-angiotensin system blockade and cognitive function in patients at high risk of cardiovascular disease: analysis of data from the ONTARGET and TRANSCEND studies. Lancet Neurol. 2010;10(1):43-53.

Diener HC, Connolly SJ, Ezekowitz MD, Wallentin L, Reilly PA, Yang S, Xavier D, Di Pasquale G, Yusuf S; for the RE-LY study group. Dabigitran compared with warfarin in patients with atrial fibrilla-tion and previous transient ischaemic attack or stroke: a subgroup analysis of the RE-LY trial. Lancet Neurol. 2010;9(12):1157-63.

Cholesterol Treatment Trialists’ (CTT) Collaboration. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet. 2010;376(9753):1670-81.

Steg PG, Mehta S, Jolly S, Xavier D, Rupprecht HJ, Lopez-Sendon JL, Chrolavicius S, Rao SV, Granger CB, Pogue J, Laing S, Yusuf S. Fondaparinux with UnfracTionated heparin dUring Revascularization in Acute coronary syndromes (FUTURA/OASIS 8): a randomized trial of intravenous unfractionated heparin during

mediate risk for coronary artery disease. Can Assoc Radiol J. 2010;61:286-90.

You JJ, Alter DA, Stukel T, McDonald S, Laupacis A, Liu Y, Ray JG. Proliferation of prenatal ultrasonography. CMAJ. 2010;182:143-51.

Haynes RB, Wilczynski NL; Computerized Clinical Decision Support System (CCDSS) Systematic Review Team. Effects of computerized clinical decision support systems on practitioner performance and patient outcomes: Methods of a decision-maker-researcher part-nership systematic review. Implement Sci. 2010 Feb 5;5:12.

Metser U, You J, McSweeney S, Freeman M, Hendler A. Assessment of tumor recurrence in patients with colorectal can-cer and elevated carcinoembryonic antigen level: FDG PET/CT ver-sus contrast-enhanced 64-MDCT of the chest and abdomen. AJR Am J Roentgenol. 2010;194:766-71.

Bassler D, Briel M, Montori VM, Lane M, Glasziou P, Zhou Q, Heels-Ansdell D, et al. Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis. JAMA. 2010;303:1180-7.

You JJ, Laupacis A, Newman A, Bell CM. Non-adherence to rec-ommendations for further testing after outpatient computed tomog-raphy and magnetic resonance imaging. Am J Med. 2010;123:557.e1-557.e8.

Ray JG, Schull MJ, Urquia ML, You JJ, Guttmann A, Vermeulen MJ. Major radiodiagnostic imaging in pregnancy and the risk of childhood malignancy: a population-based cohort study in Ontario. PLoS Med. 2010;7:e1000337.

Cheng F, You J, Rampersaud YR. Relationship between spinal magnetic resonance imaging findings and candidacy for spinal surgery. Can Fam Phys. 2010;59:e323-30.

Lee DS, Stukel TA, Austin PC, Alter DA, Schull MJ, You JJ, Chong A, Henry D, Tu JV. Improved outcomes with early collaborative care of ambulatory heart failure patients discharged from the emergency department. Circulation. 2010;122:1806-14.

YUSUF, S.Bassand JP, Afzal R, Eikelboom J, Wallentin L, Peters R, Budaj A, Fox KA, Joyner CD, Chrolavicius S, Granger CB, Mehta S, Yusuf S; on behalf of the OASIS 5 and OASIS 6 investigators. Relationship between baseline hemoglobin and major bleeding complications in acute coronary syndromes. Eur Heart J. 2010;31(1):50-8.

Chow CK, Jolly S, Rao-Melacini P, Fox KA, Anand S, Yusuf S. Association of diet, exercise and smoking modification with risk of early cardiovascular events after acute coronary syndromes. Circulation. Epub 2010 Feb 1.

Morrison KM, Dyal L, Conner W, Helden E, Newkirk L, Yusuf S, Lonn E. Cardiovascular risk factors in non-invasive assess-ment of subclinical atherosclerosis in youth. Atherosclerosis. 2010;208(2):501-5.

Mann JF, Tobe S, Teo KK, Yusuf S. Is therapy of people with chronic kidney disease ONTARGET? Nephrol Dial Transplant. 2010;25(1):42-4.

Böhm M, Baumhäkel M, Teo K, Sleight P, Probstfield J, Gao P, Mann JF, Diaz R, Dagenais GR, Jennings GL, Liu L, Jansky P, Yusuf S; ONTARGET/TRANSCEND Erectile Dysfunction Substudy Investigators. Erectile dysfunction predicts cardiovascular events in high-risk patients receiving telmisartan, ramipril, or both: The ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial/Telmisartan Randomized AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease (ONTARGET/TRANSCEND) Trials. Circulation. 2010;121(12);1439-46.

ACCORD Study Group, Ginsberg HN, Elam MB, Lovato LC, Crouse JR 3rd, Leiter LA, Linz P, Friedewald WT, Buse JB, Gerstein HC, Probstfield J, Grimm RH, Ismail-Beigi F, Bigger JT, Goff DC Jr,

Cushman WC, Simons-Morton DG, Byington RP. Effects of com-bination lipid therapy in type 2 diabetes mellitus. N Engl J Med. 2010;362(17):1563-74.

ACCORD Study Group, Cushman WC, Evans GW, Byington RP, Goff DC Jr, Grimm RH Jr, Cutler JA, Simons-Morton DG, Basile JN, Corson MA, Probstfield JL, Katz L, Peterson KA, Friedewald WT, Buse JB, Bigger JT, Gerstein HC, Ismail-Beigi. Effects of intensive blood-pressure control in type 2 diabetes mellitus. N Engl J Med. 2010;362(17):1575-85.

Flaker GC, Pogue J, Yusuf S, Pfeffer MA, Swedberg K, Granger CB, Yusuf S, Solomon SD, Ostergren J, Michelson EL, Pocock SJ, Maggioni AP, McMurray JJ for the CHARM Investigators and committees. Cognitive function and anticoagulation control in patients with atrial fibrillation. Circ Cardiovasc Qual Outcomes. 2010;3(3):277-83.

Hawkins NM, Wang D, Petrie MC, Pfeffer MA, Swedberg K, Granger, CB, Yusuf S, Solomon SD, Ostergren J, Michelson EL, Pocock SJ, Maggioni AP, Dunn FG, McMurray JJV for the CHARM Investigators and Committees. Baseline characteristics and out-comes of patients with heart failure receiving bronchodilators in the CHARM programme. Eur J Heart Failure. Epub 2010 March 31.

DeKoning L, Gerstein HC, Bosch J, Diaz R, Mohan V, Dagenais G, Yusuf S, Anand SS for the EpiDREAM Investigators. Anthropmetric measures and glucose levels in a large multi-ethnic cohort of individuals at risk of developing type 2 diabetes. Diabetologia. 2010;53:1322-30.

Gersh BJ, Yusuf S, Sliwa K, Mayosi B. Novel therapeutic concepts: the Epidemic of cardiovascular disease in the developing world: global implications. Eur Heart J. 2010;31(6):642-8. Epub 2010 Feb 22.

Lanktree MB, Anand SS, Yusuf S, Hegele RA on behalf of the SHARE Investigators. Comprehensive analysis of genomic varia-tion in the LPA locus and its relationship to plasma lipoprotein(a) in South Asians, Chinese and European Caucasians. Circ Cardiovasc Genet. 2010;3(1):39-46. Epub 2009 Dec 30.

O’Donnell M, Xavier D, Diener C, Sacco R, Lisheng L, Zhang H, Pias P, Truelsen T, Chin SL, Rangarajan S, Devilliers L, Damasceno A, Mondo C, Lanas F, Avezum A, Diaz R, Varigos J, Hankey G, Teal P, Kapral M, Ryglewicz D, Czlonkowska A, Skowronska M, Lopez-Jaramillo P, Dans T, Langhorne P, Yusuf S. Rationale and design of INTERSTROKE: a global case-control study of risk factors for stroke. Neuroepidemiology. 2010;35(1):36-44.

Mente A, Razak F, Blankenberg S, Vuksan V, Davis AD, Miller R, Teo K, Gerstein H, Sharma AM, Yusuf S, Anand SS; for the SHARE, SHARE-AP investigators. Ethnic variation in adiponectin and leptin levels and their association with adiposity and insulin resistance. Diabetes Care. Epub 2010 April 22.

Chang SM, Granger CB, Johansson PA, Kosoicharoen P, McMurray JJ, Michelson EL, Murray DR, Olofsson B, Pfeffer MA, Solomon SD, Swedberg K, Yusuf S, Dunlap ME; for the CHARM Investigators. Efficacy and safety of angiotensin receptor blockade are not modified by aspirin in patients with chronic heart failure: a cohort study from the Candesartan in Heart failure – Assessment of Reduction in Mortality and morbidity (CHARM) programme. Eur J Heart Fail. Epub 2010 Apr 23.

Mente A, Yusuf S, Islam S, McQueen MJ, Tanomsup S, Onen CL, Rangarajan S, Gerstein HC. INTERHEART Investigators. Metabolic syndrome and risk of acute myocardial infarction: a case-control study of 26,903 subjects from 52 countries. J Am Coll Cardiol. 2010;55(21):2390-8.

Pogue J, Thabane L, Devereaux PJ, Yusuf S. Testing for heteroge-neity among the components of a binary composite outcome in a clinical trial. BMC Med Res Methodol. 2010;10(1):49.

Hanley AJ, Zinman B, Sheridan P, Yusuf S, Gerstein HC; Diabetes Reduction Assessment With Ramipril and Rosiglitazone Medication (DREAM) Investigators.Effect of rosiglitazone and ramipril on beta-

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PUBLICATIONS

percutaneous coronary intervention in patients with non-ST-seg-ment elevation acute coronary syndromes initially treated with fondaparinux. Am Heart J. 2010;160(6):1029-34.

van Rees Vellinga TE, Peters RJ, Yusuf S, Afzal R, Chrolavicius S, O’Donnell M, Mehta SR, Pluta W, Sacha J, Eikelboom JW. Efficacy and safety of fondaparinux in patients with ST-segment eleva-tion myocardial infarction across the age spectrum. Results from the Organization for the Assessment of Strategies for Ischemic Syndromes 6 (OASIS-6) trial. Am Heart J. 2010;160(6):1049-55.

Sun JC, Teoh KH, Lamy A, Sheth T, Ellins ML, Jung H, Yusuf S, Anand S, Connolly S, Whitlock RP, Eikelboom JW. Randomized trial of aspirin and clopidogrel versus aspirin alone for the prevention of coronary artery bypass graft occlusion: the Preoperative Aspirin and Postoperative Antiplatelets in Coronary Artery Bypass Grafting study. Am Heart J. 2010;160(6):1178-84.

Ezekowitz MD, Wallentin L, Connolly SJ, Parekh A, Chernick MR, Pogue J, Aikens TH, Yang S, Reilly PA, Lip GY, Yusuf S; RE-LY Steering Committee and Investigators. Dabigatran and warfarin in

vitamin K antagonist-naive and -experienced cohorts with atrial fibrillation. Circulation. 2010;122(22):2246-53.

Chow CK, Lock K, Madhavan M, Corsi DJ, Gilmore AB, Subramanian SV, Li W, Swaminathan S, Lopez-Jaramillo P, Avezum A, Lear SA, Dagenais G, Teo K, McKee M, Yusuf S. Environmental Profile of a Community’s Health (EPOCH): an instrument to measure environmental determinants of cardiovascular health in five coun-tries. PLoS One. 2010;5(12):e14294.

McGorrian C, Yusuf S, Islam S, Jung H, Rangarajan S, Avezum A, Prabhakaran D, Almahmeed W, Rumboldt Z, Budaj A, Dans AL, Gerstein HC, Teo K, Anand SS; on behalf of the INTERHEART Investigators. Estimating modifiable coronary heart disease risk in multiple regions of the world: the INTERHEART Modifiable Risk Score. Eur Heart J. Epub 2010 Dec 22.

Dans AL, Teo K, Gao P, Chen JH, Jae-Hyung K, Yusoff K, Chaithiraphan S, Zhu J, Lisheng L, Yusuf S; for the ONTARGET INVESTIGATORS. In a Subgroup of High-Risk Asians, Telmisartan Was Non-Inferior to Ramipril and Better Tolerated in the Prevention of Cardiovascular Events. PLoS One. 2010;5(12):e13694.