multi-channel spectrophotometric measuring device

1
ii New Patents Method for fluorescence spectroscopic deter- mination of a biological substance provided with a marker consisting of a lanthanide chelate com- plex formed by a lanthanide coupled to the substance via a chelate forming compound, such as an EDTA-analogue, the lanthanide ion before the detection is dissociated from the active sub- stance for instance by adding a buffer with a pH value below 3.5 and a splitting detergent, whereafter the excitation in the determination takes place in the solution in the presence of a beta-diketone by using a short radiation pulse and the fluorescence from the marker is detected when the fluorescence from the noise sources has substantially ceased. 4566792 MULTI-CHANNEL SPECTROPHOTOMETRIC MEASURING DEVICE Jugoro Suzuki, Kyoto, Japan assigned to Shimadzu Corporation The disclosure is directed to a spectro- photometric measuring device equipped with a plurality of channels which automatically analyze many specimens with different testing items in a short period of time for application in biochemical automatic analysis or the like. The device of the invention is characterized in that white light from one light source is subjected to spectral diffraction through a long slit in X direc- tion and wavelength dispersion irradiation light of an optical system including a spectroscope for dispersing spectrum of monochromatic light in Y direction intersecting at right angles with the siit, is projected onto one plate surface so as to select positions of the plate surface in the Y direction and X direction, and by providing the incident end faces of the optical fibers on the selected positions for free change-over, mono- chromatic lights of arbitrary wavelengths deter- mined by the respective testing items are taken out, while the sample cell and detector are dis- posed to confront the optical fiber incident end faces for detection of intensity of light trans- mitting through the sample cell. 4566793 RECORDING APPARATUS FOR A SPECTROPHOTOMETER Shigeo Tohyama, Katsuta, Japan assigned to Hitachi Ltd A spectrophotometer to draw time changes of a plurality of spectrophotometric data by one recording pen. The spectrophotometer has a plurality of sample cells for accommodating samples to be optically measured and for enabling repeated optical measurement of each sample in a certain time interval, a timer for pro- viding a time when the sample is measured, a first memory section for respectively memorizing each pair of the repetitive measured data and time, a second memory section for memorizing the data indicative of the source point of the movement of the pen and the data representative of the destination point among each of the pairs memorized in the first memory section, an arith- metic logical unit to calculate the difference bet- ween the destination point data and source point data and to provide an output of the calculation, a pen-controller for moving the pen in response to the output of the arithmetic logical unit, and a sheet-controller for receiving the output of the arithmetic logical unit and for moving a recording sheet synchronously with the move- ment of the pen by the pen-controller. 4566797 SPECTROPHOTOMETER OPERATING AT DISCRETE WAVELENGTHS Karoly Kafia, Bela Nadai, Andra Czabaffy, Lorand Horvath, Budapest, Hungary assigned to Kozponti Elelmiszeripari Kutato Intezet The invention relates to a spectrophotometer operating at discrete wavelengths comprising diodes to emit variable, substantially mono- chromatic radiation for irradiating a sample (10) to be tested, a radiation detector (12) sensing the intensity of the radiation reflected or transmitted by the sample (10) and a signal processing unit connected to the radiation detector (12). The diodes comprise radiation sources (2) emitting substantially monochromatic radiation of dif- ferent wavelengths, a holder (1) supporting the radiation sources (2) and an optical arrangement (5,6) for transmitting the radiation emitted by the radiation sources (2) successively towards the sample (10). The optical arrangement may com- prise at least one mirror (5) supported rotatably with respect to the holder (1). The spectro- photometer is preferably provided with a control unit (3) to operate the radiation sources (2) cor- responding to the angular position of said at least one mirror (5), whereby only that one of the radiation sources (2) is operating the radiation of which is just transmitted by the mirror (5).

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Page 1: Multi-channel spectrophotometric measuring device

ii New Patents

Method for fluorescence spectroscopic deter- mination of a biological substance provided with a marker consisting of a lanthanide chelate com- plex formed by a lanthanide coupled to the substance via a chelate forming compound, such as an EDTA-analogue, the lanthanide ion before the detection is dissociated from the active sub- stance for instance by adding a buffer with a pH value below 3.5 and a splitting detergent, whereafter the excitation in the determination takes place in the solution in the presence of a beta-diketone by using a short radiation pulse and the fluorescence from the marker is detected when the fluorescence from the noise sources has substantially ceased.

4566792

MULTI-CHANNEL SPECTROPHOTOMETRIC

MEASURING DEVICE

Jugoro Suzuki, Kyoto, Japan assigned to Shimadzu Corporation

The disclosure is directed to a spectro- photometric measuring device equipped with a plurality of channels which automatically analyze many specimens with different testing items in a short period of time for application in biochemical automatic analysis or the like. The device of the invention is characterized in that white light from one light source is subjected to spectral diffraction through a long slit in X direc- tion and wavelength dispersion irradiation light of an optical system including a spectroscope for dispersing spectrum of monochromatic light in Y direction intersecting at right angles with the siit, is projected onto one plate surface so as to select positions of the plate surface in the Y direction and X direction, and by providing the incident end faces of the optical fibers on the selected positions for free change-over, mono- chromatic lights of arbitrary wavelengths deter- mined by the respective testing items are taken out, while the sample cell and detector are dis- posed to confront the optical fiber incident end faces for detection of intensity of light trans- mitting through the sample cell.

4566793

RECORDING APPARATUS FOR A SPECTROPHOTOMETER

Shigeo Tohyama, Katsuta, Japan assigned to Hitachi Ltd

A spectrophotometer to draw time changes of a plurality of spectrophotometric data by one recording pen. The spectrophotometer has a plurality of sample cells for accommodating samples to be optically measured and for enabling repeated optical measurement of each sample in a certain time interval, a timer for pro- viding a time when the sample is measured, a first memory section for respectively memorizing each pair of the repetitive measured data and time, a second memory section for memorizing the data indicative of the source point of the movement of the pen and the data representative of the destination point among each of the pairs memorized in the first memory section, an arith- metic logical unit to calculate the difference bet- ween the destination point data and source point data and to provide an output of the calculation, a pen-controller for moving the pen in response to the output of the arithmetic logical unit, and a sheet-controller for receiving the output of the arithmetic logical unit and for moving a recording sheet synchronously with the move- ment of the pen by the pen-controller.

4566797

SPECTROPHOTOMETER OPERATING AT DISCRETE

WAVELENGTHS

Karoly Kafia, Bela Nadai, Andra Czabaffy, Lorand Horvath, Budapest, Hungary assigned to Kozponti Elelmiszeripari Kutato Intezet

The invention relates to a spectrophotometer operating at discrete wavelengths comprising diodes to emit variable, substantially mono- chromatic radiation for irradiating a sample (10) to be tested, a radiation detector (12) sensing the intensity of the radiation reflected or transmitted by the sample (10) and a signal processing unit connected to the radiation detector (12). The diodes comprise radiation sources (2) emitting substantially monochromatic radiation of dif- ferent wavelengths, a holder (1) supporting the radiation sources (2) and an optical arrangement (5,6) for transmitting the radiation emitted by the radiation sources (2) successively towards the sample (10). The optical arrangement may com- prise at least one mirror (5) supported rotatably with respect to the holder (1). The spectro- photometer is preferably provided with a control unit (3) to operate the radiation sources (2) cor- responding to the angular position of said at least one mirror (5), whereby only that one of the radiation sources (2) is operating the radiation of which is just transmitted by the mirror (5).