Midwest Regional Chapter Society of Toxicology

Spring 2009 Newsletter

The MRC/SOT Proudly Presents the Annual Spring Meeting scheduled for Friday, May 1, 2009:

“Biomarkers of Toxic Injury and Therapeutic Responses”

It is with great pleasure that we extend an invitation for you to join us for the upcoming Spring meeting of the Midwest Regional Chapter of the Society of Toxicology. This meeting will discuss biomarkers of toxic injury and therapeutic responses.

~See inside for meeting details~

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27th Annual MRC/SOT Spring Meeting1 May 2009

Marriott Lincolnshire

Plans for the 27th Annual Spring Meeting of the Midwest Regional Chapter of SOT are being finalized. The meeting will be held on Friday, May 1 at the Marriott Hotel and Resort in Lincolnshire, IL. The theme for this year’s meeting is “Biomarkers of Toxic Injury and Therapeutic Responses”. The Program Committee has lined up an outstanding panel of speakers to cover this emerging and important topic. A copy of the tentative program along with the Registration form and directions to the meeting site are attached.

In addition to the featured symposium, the meeting will also include the presentation of the Young Investigator Award and the Kenneth P. Dubois Career Achievement Award, as well as a poster session featuring the annual Victor A. Dull student research competition. The winner of the competition will receive up to $1500 toward expenses for attending the SOT Annual Meeting.

All students affiliated with institutions in the MRC’s geographical region are encouraged to submit abstracts for the poster competition. The abstracts and posters may be on either original work or work that has been presented at the 2009 national SOT meeting in Baltimore. Abstracts should be submitted along with registration materials to:

Christina Wilson, Ph.D.Purdue University406 South UniversityWest Lafayette, IN 47907

For further information regarding the meeting, please contact the 2009 Program Chairman, Walt Prozialeck (wprozi@midwestern.edu or 630-515-6385).

The Awards Committee is also soliciting applications for the MRC Young Investigators Award and nominations for the Kenneth Dubois Career Award. Information regarding these awards and the application/nomination processes can be found on the MRC-SOT website.

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27th Annual MRC/SOT Spring MeetingMay 1, 2009

Marriott Lincolnshire

“Biomarkers of Toxic Injury and Therapeutic Responses”

Registration/Breakfast7:40-8:50 AM

Welcome8:50-9:00 AM

Peter Thomford, Ph.D. DABTCovance Laboratories

Validation of Novel Biomarkers of Kidney Injury

9:00-9:45 AMVishal S. Vaidya, Ph.D.,

Harvard University Medical School

Kim-1 as a Novel Biomarker of Cd Nephrotoxicity9:45-10:30 AM

Walter C. Prozialeck, Ph.D.Midwestern University

Refreshment Break10:30-10:50 AM

2009 Young Investigator Award Presentation: Investigation of Oxidative Stress Induced in Zebrafish

Embryos by Photosensitized Titanium Dioxide Nanoparticles

10:50-11:05 AMOfek Bar-Ilan

University of Wisconsin

Graduate Student Poster Session11:05-12:05 PM

Lunch12:05-1:00 PM

Business Meeting/Student Poster Awards1:00-1:30 PM

Peter Thomford, Ph.D. DABTCovance Laboratories

Hemoglobin Adducts as Biomarkersof Toxic Metabolites

1:30-2:15 PMAdnan Elfarra, Ph.D.

University of Wisconsin

Novel Biomarkers of Hepatic Injury2:15-3:00 PM

Eric Blomme, D.V.M., Ph.D.Abbott Laboratories

Refreshment Break3:00-3:15 PM

Biomarkers of Cardiac Hypertrophy and Necrosis

3:15-4:00Steve Engle, MSci.

Eli Lilly Co.

Pharmacogenetics and Pharmacogenomicsof Anticancer Agents

4:00-4:45R. Stephanie Huang, Ph.D.

University of Chicago

Panel Discussion/Q&A4:45-4:55 PM

Concluding Remarks4:55-5:00 PM

Peter Thomford, Ph.D. DABTCovance Laboratories

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MEETING INFORMATION

Regular Member: $80 (if postmarked before 4/20/2009)$100 (if postmarked 4/20/2009or after)

Non-Member: $105 (if postmarked before 4/20/2009)$125 (if postmarked 4/20/2009or after)

Full-Time Students: $10 (if postmarked before 4/20/2009) $20 (if postmarked 4/20/2009or after)

Hotel Rooms A limited number of rooms are being held for this conference. The rate is $139.00 per night. Reservations for Thursday and/or Friday can be made by calling (847) 634-0100. Rooms will be held until April 6th. Ask for the “Society of Toxicology” block.

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Directions to Conference Site

Lincolnshire Marriott Resort10 Marriott DriveLincolnshire, Illinois 60069(847) 634-0100

From the North1-94 south; exit Half Day Road; turn right (west); turn left on Milwaukee Avenue; turn left on Marriott Drive.

From the South 1-94 north; exit Half Day Road; turn left (west); turn left on Milwaukee Avenue; turn left on Marriott Drive.

From the West 1-90 east; 1-294 north; 1-94 north; exit Half Day Road; turn left (west); turn left on Milwaukee Avenue; turn left on Marriott Drive.

For additional information, contact Walter Prozialeck at 630-515-6385 or wprozi@midwestern.edu.

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2009 MRCSOT Spring Meeting Registration Form

Registration Deadline: April 20th, 2009

Return this form with payment to: Christina Wilson, PhDPurdue University406 South UniversityWest Lafayette, IN  47907Phone:  (765) 494-7440Fax:      (765) 494-9181E-mail:  wilsonc@purdue.edu

Fee Enclosed (Circle):

Pre-Registration Fee Late Registration Fee (Postmarked after 04/20/09)

Regular Member: $80 $100

Non-Member: $105 $125

Full-Time Students: $10 $20

==================================================================== Name:__________________________________________

Company/University:______________________________________________________

Address:_________________________________________________________________

City:_________________________________ State:_____________ Zip:____________

Phone Number:__________________ E-mail address: __________________________

Vegetarian Meal? Yes _____ No _____

Method of Payment?

Check: ______ *Make checks payable to the MRC-SOT* Credit Card: MasterCard _____ Visa _____ Other _________________________ Credit Card #: ______________________________ Expiration Date: ______________

Name on Card: ______________________________

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Presidents Message

I would like to extend my personal invitation to all of you to attend our spring chapter meeting. Walter C. Prozialeck and the program committee have put together what certainly will be a very interesting session on Biomarkers of Toxic Injury and Therapeutic Responses. The meeting will be held at the Marriott Hotel and Resort in Lincolnshire, on Friday 01 May 2009. Additional program information and directions to the Marriott Hotel and Resort can be found elsewhere in this newsletter.

I am pleased to welcome the following new members to the council:

 Matt Schroeder has been elected to a three year term as President.

 Susan Henwood and Lise Loberg have been elected to two year terms as Councilors.

 Molly Weiler, finishing her term as Councilor this year, has been elected to a two year term as Treasurer. 

 I extend my thanks to all of you that volunteered to run for office this year and to those of you that took time to evaluate the choices and vote. I look forward to working with these individuals for the next year and I am sure that they will be seeking your help and advice on chapter issues during their terms.

All of our members, and especially the program committee, owe a big thank you to Robin Guy who as in past years handled the negotiations for the meeting arrangements with the Marriott Lincolnshire. Robin devotes a considerable amount of her time each year to working with the Marriott Lincolnshire to insure that the spring meeting is a success.

As a reminder, especially to our student members, our national SOT organization does have a program to defray travel expenses in order to encourage students to attend the meetings of regional chapters. The current guidelines state that students must be four hours away from the meeting site to be eligible for the award. National is committed to having strong regional chapters and has implemented this program to help the chapters achieve this goal. If you have any questions about the travel program please contact me or any other council member.

We would like to hear from you regarding future meeting topics and sites. Hosting the fall meeting is a great opportunity to showcase your facilities and organization. Please feel free to contact anyone on the council with your questions or ideas. Please encourage your colleagues to become members of our chapter and remember that you do not have to be a member of National to be a member of our regional chapter. Membership information and applications are posted on our web site.

Please consider running for office or serving on a committee as the nominating committee will be seeking nominations this year. Our by-laws are posted on the web site and this is a great way to learn more about the duties of the officers and councilors. Since so much of the work of the Council and committees is conducted electronically, it has become much easier to participate.

I look forward to seeing many of you on May 1st.

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Peter J. Thomford Ph.D., DABT

We wish to thank The following sponsors for their generous contributions:

Covance Laboratories

Reid Patterson Consulting Inc

Robin Guy Consulting, LLC

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**MRC/SOT AWARDS**MRC/SOT is proud to recognize the efforts of toxicologists who work and study in the Midwest. There are three annual awards presented that the MRC/SOT uses to highlight their achievements:They were awarded to the following individuals at the Annual Spring Meeting, May 16, 2008.

Kenneth P. DuBois Award (1982-present)Patricia Frank was announced as the 2008 recipient of the Kenneth Dubois award. This award is presented annually at the MRC/SOT Spring meeting to an outstanding toxicologist from the Midwest region.

Nominations due April 1, 2009. (DEADLINE EXTEND TO APRIL 8, 2009)

Victor A. Drill Award (1989-present) Sponsored by WIL Research Laboratories, Inc. This award is presented annually at the MRC/SOT Spring meeting to the student who presents the best poster. The winner receives a paid trip (expenses up to $1500) to the following year’s national SOT meeting.

The 2008 1st place poster winner was Sandeep Gopalakrishnan, University of Wisconsin at Milwaukee for his poster entitled “Hyperglycemia-induced oxidative stress is attenuated in cardiac tissue by 670 nm photobiomodulation in an experimental model of diabetes.”.

The 2008 2nd place poster was Daniel S. Lark, University of Wisconsin at Milwaukee for his poster entitled “Effect of photobiomodulaton on glutathione redox status of gastrocnemius muscle in an animal model of diabetes.”

Abstracts due April 1, 2009. (DEADLINE EXTEND TO APRIL 8, 2009)

Young Investigator Award (2003-present) Sponsored by Covance Laboratories Ofek Bar Ilan, University of Wisconsin School of Pharmaceutical Sciences, was the winner of the young investigator award which is presented to the student who submits the best research proposal prior to the MRC/SOT Spring meeting. The -winner receives $1500 to put towards their proposed research project and presents their results at the following year’s MRC/SOT Spring meeting.

Proposals due April 1, 2009. (DEADLINE EXTEND TO APRIL 8, 2009)

Information about the three awards, as well as application forms, are found on our website (www.toxicology.org/memberservices/regionalchapter/midwest/ ). Any further questions may be directed to the Executive Committee.

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Regional Chapter Graduate Committee (RC-GC)

Greetings Midwest Regional Chapter! My name is Ofek Bar-Ilan and I am the Regional Chapter/Special Interest Group Graduate Committee (RC/SIG-GC) representative for the Midwest Regional Chapter (MRC)-SOT. As an ad hoc committee of the national Society of Toxicology, the RC/SIG-GC was created to serve as a student liaison between the regional and national SOT chapters in order to encourage student involvement in SOT. If you are a student and have an active interest in toxicology, we encourage you to attend the next MRC-SOT meeting on May 1, 2009 at the Lincolnshire Marriott Resort in Lincolnshire, IL. Even though you do not need to be a member of the Midwest Regional Chapter to attend the meeting or present a poster, there are several benefits to becoming a student member. Student members have access to several services provided by the MRC-SOT, are eligible for student travel awards such as the Victor A. Drill Award for best poster presentation and the Young Investigator Award for the most innovative research. You also benefit from networking with other scientists and potential employers at the regional meetings. Besides, membership dues are only $10! To become a member, you can either download an application form from our website (which does

not require national membership) or designate your choice to join while paying national SOT dues. Please feel free to email me with any questions you have about regional and national SOT student awards and meetings or volunteer opportunities at the annual SOT meeting.

Hope to see you May 1!

Ofek Bar-IlanRC-GC RepresentativeDivision of Pharmaceutical SciencesUniversity of Wisconsin-Madison777 Highland AveMadison, WI 53705Phone: 608-262-4525Email: barilan@wisc.edu

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INTERESTED IN SERVING ON THE MRC/SOT EXECUTIVE COMMITTEE?Annual elections are held to fill various vacant positions in the MRC/SOT executive committee. Nominations are accepted annually for vacant positions. For the 2009-2010 the following executive committee positions were filled: President-elect-Matthew Schroeder, Treasurer-Molly Weiler, Councilors-Lise Loberg and Susan Henwood

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President Peter J. Thomford, Ph.D, DABT.Covance LaboratoriesTelephone: 608.395-3683Peter.Thomford@covance.com

President-ElectWalter ProzialeckMidwestern University Chair: Program CommitteeMembers: Walter ProzialeckPhone: 630-515-6385wprozi@midwestern.edu

Past PresidentDon W. Korte, Jr., PhD, DABT, FCAConcordia University WisconsinPhone: (262) 243-4268don.korte@cuw.eduChair: Nominating Committee

SecretaryLouette Rausch, M.S.Akzo NobelPhone: (312) 544-7061louette.rausch@akzonobel.comChair: Newsletter/Communications CommitteeMembers: Louette Rausch

TreasurerChristina Wilson, PhDPurdue UniversityPhone: (765) 494-7440wilsonc@purdue.edu

CouncilorsJane FagerlandAbbottjane.fagerland@abbott.com

Oliver PelzBP CorporationPhone: (630) 420-3650 (630) 420-5375 oliver.pelz@bp.com organizatio n:

Molly Weiler, Ph. D., DABTCovance LaboratoriesPhone: (608) 242-2626molly.weiler@covance.com

Regional Chapter Graduate Committee RepresentativeOfek Bar-IlanDivision of Pharmaceutical SciencesUniversity of Wisconsin-MadisonPhone: 608-262-4525 barilan@wisc.edu

The MRC-SOT newsletter is published biannually in both print and electronic formats as a service to the toxicology community of the Midwest. Contributions are welcome! Please address any questions, comments or contributions to Louette Rausch at the email address above.

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