measuring the latency of the frequency following response ... · new handbook of auditory evoked...

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Template produced at the Graphics Support Workshop, Media Centre Figure 3: Example data from two listeners (by row). The top row shows a full set of FFR points with all six group delays within the accepted range. The bottom row shows incomplete data with many FFR points not above noise floor, and consequently missing group delays. 80 100 120 140 -0.2 -0.1 0 0.1 0.2 0.3 0.4 0.5 0.6 440 460 480 0.5 0.6 0.7 0.8 0.9 1 1.1 1.2 1.3 660 680 700 720 -0.6 -0.5 -0.4 -0.3 -0.2 -0.1 0 0.1 0.2 80 100 120 140 -0.2 -0.1 0 0.1 0.2 0.3 0.4 0.5 0.6 Modulation Phase (periods) 9.3 ms 8.5 ms 440 460 480 0.5 0.6 0.7 0.8 0.9 1 1.1 1.2 1.3 Lower Side-Tones 7.6 ms 5.3 ms 660 680 700 720 -0.6 -0.5 -0.4 -0.3 -0.2 -0.1 0 0.1 0.2 Higher Side-tones Vertical 3.1 ms Horizontal 3.3 ms Frequency (Hz) 7.2 ms 7.6 ms Means t, p Discussion Results Was any FFR recorded? Unwrapping the phase Further Study Methods Listeners Stimuli Electrode montages . Measuring the latency of the frequency following response through group delay Andrew King ([email protected]), Kathryn Hopkins, Christopher J. Plack Audiology and Deafness Research Group, School of Psychological Sciences, University of Manchester. References New handbook of auditory evoked responses Mod LST HST Vertical 20 20 18 Horizontal 14 15 17 0 10 20 -0.5 0 0.5 0 10 20 -0.5 0 0.5 0 10 20 -0.5 0 0.5 5 10 20 -1 -0.5 0 0.5 Time (ms) Amplitude Modulation Lower tone Fc Higher tone 85 491 576 661 100 476 676 115 461 691 130 446 706 145 431 721 Introduction What is Group Delay? Aim Figure 1: A diagram of a system with a group delay of 150 ms (purple dashed lines). Right Panel: Sine waves (grey) at 21 to 25 Hz are input with starting phases of 0. The output (solid black) starts 150 ms later; its Fourier Transform (dashed black) extrapolates back in time to different starting phases (yellow circles). Left panel: the transformed phase (relative to cosine) as a function of frequency. The slope of the fitted line is the negative sign of the delay in seconds. Figure 2: An example of the positive polarity (top left) and negative polarity (top right). Adding the two polarities enhances the envelope and cancels the fine structure. Subtraction cancels the envelope and enhances the fine structure. Figure 5: A diagram showing the composite stimuli of 4 AM tones presented, two to each ear. Each ear receives one tone with slow modulation, one tone with fast modulation, one tone with low frequency fine structure and one with high frequency fine structure. (Hz) (periods) Time (ms) = −0.05 + 0.64 Amplitude Figure 4: Mean Group Delay (+/- 95% CI) for the two montages from listeners who had acceptable group delay in both vertical and horizontal montages (statistics inset). N = 13 d = 0.05 t = 0.15 p = 0.89 N = 13 d = 1.74 t = 5.94 p < 0.001 N = 14 d = 0.92 t = 2.43 p = 0.03 Conclusions Figure 6: The phase coherence of fine structure FFR over 10,000 trials plotted against interaural phase difference discrimination thresholds in the fine structure of AM tones (Fc = 500 Hz). One data point per listener with age labelled by marker colour. Age

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Page 1: Measuring the latency of the frequency following response ... · New handbook of auditory evoked responses Mod LST HST Vertical 20 20 18 Horizontal 14 15 17 0 10 020 -0.5 0 0.5 10

Tem

pla

te p

roduced a

t th

e G

rap

hic

s S

up

po

rt

Wo

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op

, M

edia

Centr

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Figure 3: Example data from two listeners (by row). The top row shows a full set of FFR points with all six group delays within the accepted range. The bottom row shows incomplete data with many FFR points not above noise floor, and consequently missing group delays.

80 100 120 140

-0.2

-0.1

0

0.1

0.2

0.3

0.4

0.5

0.6

440 460 480 0.5

0.6

0.7

0.8

0.9

1

1.1

1.2

1.3

660 680 700 720 -0.6

-0.5

-0.4

-0.3

-0.2

-0.1

0

0.1

0.2

80 100 120 140

-0.2

-0.1

0

0.1

0.2

0.3

0.4

0.5

0.6

Modulation

Ph

ase (

peri

od

s)

9.3 ms

8.5 ms

440 460 480 0.5

0.6

0.7

0.8

0.9

1

1.1

1.2

1.3

Lower Side-Tones

7.6 ms

5.3 ms

660 680 700 720 -0.6

-0.5

-0.4

-0.3

-0.2

-0.1

0

0.1

0.2

Higher Side-tones

Vertical

3.1 ms

Horizontal

3.3 ms

Frequency (Hz)

7.2 ms 7.6 ms

Means

t, p

Discussion

Results

Was any FFR recorded?

Unwrapping the phase

Further Study

Methods Listeners

Stimuli

Electrode montages

.

Measuring the latency of the frequency following response through group delay

Andrew King ([email protected]), Kathryn Hopkins, Christopher J. Plack Audiology and Deafness Research Group, School of Psychological Sciences, University of Manchester.

References

New handbook of auditory evoked responses

Mod LST HST

Vertical 20 20 18

Horizontal 14 15 17

0 10 20

-0.5

0

0.5

0 10 20

-0.5

0

0.5

0 10 20

-0.5

0

0.5

5 10 20

-1

-0.5

0

0.5

Time (ms)

Am

pli

tud

e

Modulation Lower tone Fc Higher tone

85 491

576

661

100 476 676

115 461 691

130 446 706

145 431 721

Introduction

What is Group Delay? t

Aim

Figure 1: A diagram of a system with a group delay of 150 ms (purple dashed lines). Right Panel: Sine waves (grey) at 21 to 25 Hz are input with starting phases of 0. The output (solid black) starts 150 ms later; its Fourier Transform (dashed black) extrapolates back in time to different starting phases (yellow circles). Left panel: the transformed phase (relative to cosine) as a function of frequency. The slope of the fitted line is the negative sign of the delay in seconds.

Figure 2: An example of the positive polarity (top left) and negative polarity (top right). Adding the two polarities enhances the envelope and cancels the fine structure. Subtraction cancels the envelope and enhances the fine structure.

Figure 5: A diagram showing the composite stimuli of 4 AM tones presented, two to each ear. Each ear receives one tone with slow modulation, one tone with fast modulation, one tone with low frequency fine structure and one with high frequency fine structure.

𝒇 (

Hz)

𝝓 (periods)

Time (ms)

𝜙 = −0.05𝑓 + 0.64

Am

pli

tud

e

Figure 4: Mean Group Delay (+/- 95% CI) for the two montages from listeners who had acceptable group delay in both vertical and horizontal montages (statistics inset).

N = 13

d = 0.05

t = 0.15

p = 0.89

N = 13

d = 1.74

t = 5.94

p < 0.001

N = 14

d = 0.92

t = 2.43

p = 0.03

Conclusions

Figure 6: The phase coherence of fine structure FFR over 10,000 trials plotted against interaural phase difference discrimination thresholds in the fine structure of AM tones (Fc = 500 Hz). One data point per listener with age labelled by marker colour.

Age