mc drug lecture
TRANSCRIPT
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PSUPT GRACE M EUSTAQUIO
PNP Crime Laboratory
CLASSIFICATION OFDANGEROUS
DRUGS AND THEIREFFECTS
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Drugs and Medicine
Drug is a substance other than foodintended to affect the function of thebody. (Webster dictionary)
Medicine is a substance in certain
doses which when taken into thehuman body cures illness and/orrelieves signs/symptoms of disease
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Dangerous Drugs
Any substance listed in RA 9165
(1988 UN Convention, 1961 UN ConventionNarcotic Drugs as amended in 1972)
A substance affecting the CNS which when
taken into the human body brings aboutphysical, emotional or behavioral changes in a person taking it.
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What is Dangerous Drug?
Listed in the schedules annexed to
1961 Single Convention on Narcotic Drugs amendedby 1972 Protocol
1971 Single convention on PsychotropicSubstances.
PGMA signed RA 9165 on June 7, 2002 and it tookeffect on July 4, 2002.
Signed: June 7, 2002
Published: June 19, 2002Took effect: July 4, 2002IRR: August 30, 2002 andpublished October 31,
2002
Comprehensive dangerous drug act of 2002
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Drug Dependency
Cluster of physiological, behavioral andcognitive phenomena in which use of a drugresulting a strong desire and difficulties of
controlling it. (WHO definition)
Drug dependency test- the method of treating
the person addicted to a particular narcotic orpsychoactive drugs.
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Drug Chemistry
Drug Chemist specialistsconduct chemical analyses ofevidence confiscated duringcriminal investigationsinvolving dangerous drugs andclandestine labs.
Solid dosage samples:-street drugs- prescription drugs- chemically engineered designer
drugs in the form of liquids,powders, residues and plant materialare identified.
Qualitative and Quantitative
examination - analyticalmethod of identifying
dangerous drugs and volatilesubstances.
Drug test- the process of
determining the presence of adrug and its metabolites inbody fluids.
As an expert witness, the analyst presents his or her findings in a court of law.
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General Classification of Dangerous Drugs
Street Drugs Club Drug
Dangerous Drugs
GHB/Flunitrazepam
Ecstacy
Prescription drug
Narcotics
Diazepam
Methamphetamine
Barbiturates
Marijuana
Opiates
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Classification of dangerousdrugs
Narcotics (pain killer)
Depressants (downers)Stimulants (uppers)
Hallucinogens(psychedelic)
Designer drug (club drug)
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NARCOTICS
Used to eliminate pain by relaxingmuscle from overuse or injuries.
Addictive painkillers are classifiedas Opiates and Analgesics
• Variety of substance that dulled senses• Legally composed of opiates and derivatives
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Any part of the plant of the species• Papaver Somniferum L. (wild coast Mediterranean) • Papaver Setigerum L. (west Asia)
• Papaver orientale (Asia)
• Papaver Bracteatum • Papaver Rhoeas
Prohibited even for floral, decorative or culinary (breadseasoning) purposes.
Opium Poppy
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The coagulated juice of opium poppy (Papaver
Somniferum L.)
Also includes crude or preparations containingmorphine or any alkaloid of opium as an ingredient.
Opium
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OPIUM produces more drugs
through chemical processes.
OPIUM MORPHINECODEINE
HEROIN
MORE
DERIVATIVES
MORPHINE
Analgesics are painkiller used
to treat opiate abusers.
Eff f O i i h b d
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Effects of Opiates in the bodyInhibits cells in the brain stem thatare responsible for respiration -
slows down, and in some casescompletely stops breathing!
Stimulates cells of the vomitingcenter in the brain stem, causing
nausea and vomiting.Inhibits intestinal peristalsis, causingconstipation.
Binds to cells of the hypothalamus,therefore affecting hormone release
throughout the body. Lowerstestosterone levels.
The use of needles for IV druginjection provides an entryway formany kinds of infections.
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Heroindiesel, smack, scag , heron , black tar , horse , junk ,
brown , dark and H .
Heroin or diacetylmorphine (INN) is a semi-synthetic opioid. It is the 3,6-diacetyl derivative of
morphine (hence diacetylmorphine ) and issynthesized from it by acetylation. The whitecrystalline form is commonly the hydrochloridesalt, diacetylmorphine hydrochloride
Speedball – mixtureof cocaine withheroin or morphine
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A heroin user: This woman has just cooked up some heroin in the
doorway, and is now injecting it into her leg
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Short- and Long-Term Effects of Heroin Use
Short-Term Effects Long-Term Effects
•"Rush"•Depressed respiration•Clouded mentalfunctioning•Nausea and vomiting•Suppression of pain
•Spontaneous abortion
•Addiction•Infectious diseases, for example,HIV/AIDS and hepatitis B and C•Collapsed veins•Bacterial infections•Abscesses
•Infection of heart lining and valves•Arthritis and other rheumatologicproblems
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Prescription Drugs
SedativesUsed to calm the nerves, reducetension and induce sleep.
Sedatives were usually used in date
rape cases. Examples are alcohols,barbiturates, tranquilizers.
Ethyl alcohol is not included in RA
9165.
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Barbiturates
First synthesize (1863) byAdolf von Baeyer (GermanChemist).
The word "barbiturate" is acombination of "Barbara" with"urea": von Baeyerdiscovered it on SaintBarbara’s Day, and urea
was used in the synthesisof the new molecule.
Barbara + Urea
Common name stem from the color of the capsuleor tablet (e.g. “yellow jackets”, “blue devils”,
rainbow, Amy’s and “reds”.
The agent thatcause Marilyn
Monroe's death
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Tranquilizers(Benzodiazepam)
Major and minor tranquilizers
Examples are rohypnol, valium etc
Combining with alcohol (in substantialamount) can lead to coma or evendeath.
Tolerance can cause physical
dependence, with typical withdrawalsymptoms ranging from nightmares toconvulsions when the drug intake is
stopped.
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Effects of prescription
drugs under Schedule IV
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Depressants has been associatedwith an increased incidence ofinfection with bacterial meningitis.The pus that accumulates on the
tissues surrounding the brain isvisible in this picture.
Depressants can provide anentryway into the body formicroorganisms that attack anddestroy heart valve tissue. The toppicture shows a normal aortic valve;the bottom picture shows one thathas been “chewed away” by
infective endocarditis.
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Depressants provides an entryway into the body for the viruses thatcause different types of hepatitis.This picture shows the damage toliver tissue that hepatitis can cause.
Over time, hepatitisinfection can lead tocirrhosis of the liver. Thisoccurs more commonlywith hepatitis B, but cansometimes occur with
hepatitis C.
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IV Drugs: IV
drug use hasalso beenassociatedwith anincreased
incidence ofinfection withtuberculosis.The lungpictured has
beensignificantlydamaged bysuch infection.
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Street Drugs
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Ephedra plant (MaHuang)
Methylamphetamine
Originally synthesized fromEphedrine in Japan by Dr NagayoshiNagai (1888).
NH
CH3
R
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Origin of the word “Shabu”
“Shabu” is a
japanese word
"shabu-shabu" isan onomatopoeia(imitate sound)representing thesound meat
makes whenswished throughthe bubblingwater.
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Methamphetamine
ESTIMATES OF USE 33 million globally (0.8% adult population)
2/3 in Asia
Thailand 6.9% of adult population Philippines 2.8% adult population
Japan 1.8% adult population
ROUTE OF ADMINISTRATIONSwallowing SnortingSmoking (chasing the dragon)Injecting
Paraphernalia
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Paraphernalia“Chasing the Dragon ” Meth & Heroin users
FOIL: Converts
crystal into gasessuitable for smoking.
The shiny side of thefoil is the one who
touches the flame.
LIGHTER: Thesource of heat thatconverts thecrystals into gases.Rolled aluminumfoil or metal withhollow openingon both sides
TOOTER: Aids insmoking gasesconverted fromburningmethamphetamine.
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Effect in the body
As a stimulant, this
substances mimic thehormones (symp, parasympetc) responsible for therelease of energy in the body.
Used to increase mental
activity, relieve fatigue andoffset drowsiness.
Meth changes the heart muscle
fibers (normal fibers are on theleft, damaged fibers on the right).The fibers on the right have lostmany of their cross-striations,which can lead to decreasedcardiac contractility.
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Effects of Stimulants
Pregnant woman can cause mental retardation totheir unborn babies
Extended wakefulness and increased mentalalertness
Loss of memory Irritability, anxiety and fear
Loss of sexual desire, lacks interest towards work
Chronic snorters suffer from irritation of the nose tofrequent nose bleeding
Loss of appetite resulting in decreased bodyweights
C i
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Cocainecoke, crank, snow, crack (crystalline
free-base form), zip
Originated from Erytroxylon coca(Found in S America & Java)
Used as a Local anesthetic inminor surgery.
Most Potent natural stimulant
Some users combine cocainepowder or crack with heroin in
a "speedball.“
The word “coca” is a pre-Incan Tiwanaku wordKhoka means “the plant”
Chewed to produce mild
and long lasting euphoria
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snorted, smoked, or injected
Oral (chewing)
Snorted, (nasal tissues to bloodstream)
Injected, (bloodstream).
Smoking (inhaling vapor or smoke into the lungswhere absorption into the bloodstream is asrapid as by injection).
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Effects of Cocaine
Cocaine use causes peripheralblood vessels to constrict, whileheart rate and blood pressurerise. This can cause heartfailure, and can also cause bloodvessels in the brain to explode,
leading to brain damage and/ordeath.
Extends the activity of
dopamine by blocking itsreabsorption. Dopamine is aneurotransmitter that transmits
“pleasure signals” in the brain.
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Added Danger: Cocaethylene
When people mix cocaine andalcohol consumption, they arecompounding the danger fromeach drug.
This is because the human livercombines cocaine and alcoholand manufactures a thirdsubstance, cocaethylene, whichintensifies cocaine's effects,including increasing the risk ofsudden death.
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Hallucinogens are drugs that can producechanges in mood and behavior and can produce
delusions and hallucinations.
A user may speak of “hearing” colors, and
“seeing” sounds.
HALLUCINOGENS
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Marijuana, Cannabis or Indian Hemp:Embraces every kind, class, genus or specie of the plant Cannabis
Sativa L including Cannabis Americana, hashish, bhang, guaza,churrus and ganjab
Cannabis Sativa is an annual plant growthwild in many temperate parts of the world.It consist of crushed cannabis leaves and
its flowers
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Cannabis plants are either male or female.
The male plants produce pollen which pollenates theflowers of the female plant, which once pollenized,
produce seeds.
If the female plant isn't pollenized (if there are no maleplants nearby producing pollen), the flower/buds
continue to develop and produce THC.
Female plants which are not pollenized are referred to
as sensemilla (without seeds).Usually 40-50% of the plants are male.
Cannabis plant
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1. Panama red
Forms of Marijuana
2. Sinsemilla – flowering top of seedless plant
a. many growers believed that unfertilized female flowers,
when left to grow to maximum maturity, would produce moreTHC than a similar seed-bearing bud.b. unseeded buds would produce more smokeable materialthan seeded flowers.
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1. Cigarette rolling paper (Zig zag) - A brand ofrolling papers famous for the silhouette of a beardedsmoker on the label.
Marijuana Paraphernalia
2. Water pipe -
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cannabis smoke is passed through water before inhaling. This has the effectof cooling the smoke and to some extent filtering the smoke by removing the
heavy tar elements.
This produces a less harsh and safer smoke, especially if you smoke purecannabis without any horrible tobacco contaminating the high.
Smoking in this way gets you stoned much quicker than joints andinexperienced smokers might find they get too high too quickly, particularly if
they aren't many people sharing the hits.
Marijuana vaporizers work by heating the cannabis to a temperature where activeingredients evaporate into a thin mist. Specifically, the cannabis heats to atemperature of 356 - 392 degrees Fahrenheit, below the point of combustionwhere smoke is produced. Without combustion, the amount of carcinogens, ortoxins, decreases. Depending on the design of the vaporizer, the vapor is thencaptured in a glass and inhaled via a tube. It's important to know that reliable data
to support this technique as less risky to health is limited.
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1. Viper - 1930s hipsters who frequented tea pads and
smoked jive; onomatopoeic from ssssssssst, the soundmade by an inhaling pot-smoker.
Marijuana Users
Bong pipe
Popular figures in movies television and the
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Popular figures in movies, television, and the
music industry support the use of marijuana.
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Or are perceived as supporting marijuana use
Eff t f M ij th
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Effects of Marijuana on theBrain
THC damages and destroys nerve cells ofthe hippocampus, a part of the brain thatis crucial for learning, memory, and theintegration of sensory experiences with
emotions and motivation. Marijuanaabuse is thus associated with attentionand memory problems.
It has been shown to cause changes inthe brain that “prime” the user to becomemore easily addicted to other drugs.
Eff t f M ij th
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Effects of Marijuana on theLungs
The daily use of one to three marijuana joints produces approximately the samelung damage and potential cancer risk as
smoking five times as many cigarettes!Thus MJ users are prone to cancers astobacco users.
Users are also more likely to get bronchitisand chest colds.
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Social Costs
Students who smoke marijuana get lower gradesin school and are less likely to graduate, thatstudents who do not smoke marijuana.
Employees who smoke marijuana have moreaccidents, increases tardiness rates, reducedattentiveness and, a general loss inproductivity.
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DESIGNER DRUGS
Combination of effects and chemically related but different effectto known narcotic and psychotropic substances
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Designer Drugs
Combination of effects and
chemically related but differenteffect to known narcotic andpsychotropic substances
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MDMA – Methylene dioxy MethamphetamineEcstacy, Adam, Eve, superman, martian etc
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MDMA(3,4-Methylenedioxymethamphetamine)
-commonly known as ecstasy, X, E, XTC, Hug, beans etc.
-semi-synthethic & psychoactive compound.
-shares stimulant & hallucinogenic attributes of LSD& amphetamine.
-Considered neurotoxic.
- mol. wt.: 193.25 g/mol
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ECSTACY
Superman Smiley Sunflower Footprint (20:5:1) Daisy (4:1) Omega
MDMA MDMA MDA Caffeine:Meth:MDMA Caffeine:MDMA none
Dove (4:1) Sunshine (1.2:1) Duck Fish
MDMA:Meth PCP: Pseudo/ephedrine MDMA MDMA
Bat Crab Butterfly (50:5:5) V8 (3:1)
MDMA MDMA Caffeine:Meth:MDMA MDMA:Caffeine
Euro (1:1) Rainbow Split (1:1) Martian/ Jollibee Star UnknownMDMA:Meth Pseudo/ephedrine Cariprosodol:Meth (2:1) MDMA:Meth MDMA Carbamezipine
Clover (15:5:2:1)
Caffeine:MDMA:Meth:Pseudo/
ephedrine
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Did You Know?
Ecstasy is both a stimulant and hallucinogen.
Ecstasy is sold mostly in pill form, but alsocomes in powder
Ecstasy pills are made in illegal labs.
Ecstasy has been known to containamphetamines, tranquilizers, coughsuppressants, and caffeine.
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How Will Ecstasy Affect Me?
Dehydration
Heat stroke
Rapid heartbeat
High blood pressure
Faintness
Seizures
Unconsciousness
Death
Ecstasy/MDMA: Damage to
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Ecstasy/MDMA: Damage toSerotonin-Producing Neurons
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WHY IS ECSTASY USED?
1. RAVE PARTIES
- designed to be conducive toenjoying the ecstasy experience.
-Ecstasy enhance prioreception (deepbody sense). It makes movementnotably pleasant.
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2. SELF-PSYCHOTHERAPHY
- The hit of ecstasy is worth 3
months ofconventional psychotherapy.
- It helps in the surfacing ofrepressed memories & emotional problem.
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3. SUBSTITUTE FOR SPEED
- It can be used in activities thatrequire concentration, motivation & energy.
4. SENSORIUM
- Sensory enhancement of MDMA makes
sensual activity unusually enjoyable.
- Touching can become more such intenselypleasurable.
K t i
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Ketaminejet, super acid, Special "K", green, K, cat Valium
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Ketamine
Appearance: Comes in a clear liquidand a white or off-white powder form.
ketamine
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History
Ketamine was first synthesized in 1962 inan attempt to find a safer anestheticalternative to PCP, which was more likely
to cause hallucinations and seizures.
The drug was first used on American soldiers during the Vietnam War, but isoften avoided now because it can causeunpleasant out-of-body experiences
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How is Ketamine used?
Ketamine is a tranquilizer most commonlyused on animals.
The liquid form can be injected, consumed
in drinks, or added to smokable materials.
The powder form can be used for injectionwhen dissolved.
In certain areas, Ketamine is being injectedintramuscularly.
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GHB – Gamma Hydroxy Butyrate
Rohypnol/ Flunitrazepam
GBH, Liquid E, Liquid X
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GHB
GHB is usually availableas an odourless,colourless liquid whichyou drink (it tastes slightlysalty).
Sometimes the substance
is available as a powder,or in a capsule. In itsliquid form, GHB is sold insmall (30ml) bottles; thiswould normally be enoughfor three doses. It isdifficult to give a clear'safe' dose, as the
concentration of the liquidwill vary.
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Rohypnol
This drug has gained the reputation as
being a "date rape" drug due to itspowerful hypnotic effects that induce asleepy, relaxed, almost drunk feeling thatlasts up to eight hours.
Street value of Illegal Drugs
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Street value of Illegal DrugsSource- DDB
Heroin (P 9T/ gram)Cocaine (P 5T/ gram)
Shabu (P 5T/ gram)
Ecstacy (P 1,500/ tablet)Valium (P 15/ tablet)
Marijuana
cigarette (P 8/ stick) hashish (P 250/ gramfruiting tops (P 25/ gram) cake (P 40/ gram)
teabag (P 25) plants (P 200)
seeds (P 25-40)
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Ethyl Alcohol
Reduces performance during tasks that requiremental and physical agility
# 1 Date Rape Drug Alters perceptions & Lowers inhibitions
Impairs judgment & Causes amnesia “blackouts”
Less likely to engage in physical resistanceand verbal assertiveness when confronted with
unwanted sexual advances Less effective of removing themselves from an
unsafe situation
Forensics aspects of blood
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Forensics aspects of bloodalcohol examination.
Blood is used for confirmatory examinationof the degree of alcohol intoxication.
NBI & PNP Crime Lab are the onlygovernment agencies capable ofconducting such examinations.
5 drinks in two hours will raise the bloodalcohol content the point of legalintoxication
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Ex. Rugby, thinner, solvent, gasoline andother gasoline-based products, kerosene,nail polish, cuticle remover, lighter fluid and
dry-cleaning fluid.
Inhalants
Inhalants are volatilesubstances derived from ether orchloroform. It is inhaled through
the nose or through the skin toexperience intoxication. Liquidpaper
Inhalants: Glue Paint Thinner
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Inhalants: Glue, Paint Thinner,Gas, Aerosol Propellants, etc.
The fumes can displace oxygen inthe lungs, causing the body tosuffocate. Nerve damage, brain
damage, and even death can result.Some chemical components ofthese products can cause: Heart failure Hearing loss
Liver and Kidney damage
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Research has shown that marijuana negatively
affects driving ability because of altered sense
of time and space as well as slowed reaction
time.In 2000 46.5% of arrests for drug abuse
violations were for marijuana.
646,042 people were arrested for possession of marijuana.
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Compared to Cocaine, Heroin,Methamphetamines, and other drugs.Marijuana accounts for an estimated 3.9%
of crime.Marijuana accounts for an estimated $10.7
billion (16.3%) in drug related spending
each year.
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Conclusion
Marijuana is an intensely popular drug, it is
estimated that one third of the population uses
marijuana.
Marijuana is a controversial drug whose truesocial cost has not really been measured.
Marijuana is also a drug with exceptional
medical possibilities, if it can over come itsbad reputation.
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Other sectors involved
Participation of family, students,teachers and school in drugenforcement.
Private and Labor sector and DOLEfor a drug-free workplace program.
The role of church and the communityfor the enforcement of this act.
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Thank You!
“That In All Things: GOD May Be Glorified”