May 15, 2019

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Our Mission

To bring the highest levels ofpharmaceutical science and innovation

to the physician-dispensed skin care industry while creating a new category of products

designed to be synergistic with procedures

Innovative, Best-in-Class Topical Products

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• TriHex Technology® peptide platform

technology stimulates elastin and

collagen deposition in the skin and

recycles the extracellular matrix

– Procedure Enhancement System

– Restore & Renew daily skin care line

• Rapid market adoption and sales ramp

Patented, DifferentiatedTechnology

• Procedure Line addresses the need for

synergistic topical products for the

aesthetic procedure market (use with

laser resurfacing, CoolSculpting, Kybella,

fillers, surgery, RF, etc)

• Peri-procedure: prep the skin, speed

healing and improve outcomes

• Breakthrough TransFORM Body product

has extensive growth potential

Procedure-paired productsexpand the Aesthetic Market

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Alastin’s Patented TriHex Technology®Re-establishes Functional Skin Matrix Processes Pre and Post Procedure

A Combination of Critical Synergistic Ingredients

• Recycles the skin matrix, clearing out sun damage and by-products of aging

• Helps support the skin’s ability to generate new collagen and elastin

Key Ingredient Activity

tripeptide-1 Modulates and clears damaged collagen and elastin in the skin matrix

hexapeptide-12 Optimizes fibroblast function and binds elastin

phosphatidylserineControls damaging proteases, increases procollagen, combats glycation end products (AGEs)

oleuropeinActs as an anti-oxidant, clears damaged skin matrix proteins, combats glycation end products (AGEs)

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Pairing an Innovative Topical Product

with Body Shaping Devices to Address Unmet

Market Needs

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Unmet Needs: Body Contouring Market

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91%of patients

would benefit

from a take

home topical

88%of patients

would like to

see results more

quickly following

body fat reduction

54%of patients

still have loose/

crepey skin

following body

contouring

procedures

88%of patients

would be

interested in a

topical body

product without

a procedure

Alastin Advisory Board Meeting 2018Feedback on Needs for Skin Tightening and Fat Reduction Procedures

TransFORM Body Treatment with TriHex Technology®

Launched October 2018

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Provides Benefits When Used:

• With non-surgical body fat reduction procedures to speed and enhance fat loss

• Alone or with a skin-tightening procedure to tighten loose, crepey skin

TransFORM Body Treatment

with TriHex Technology®

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LipoDRONE™ Delivery System

Liposome-encapsulated peptide

supports breakdown and digestion

of lipid droplets post-cryolipolysisor RF fat reduction procedure

Clinical Study Demonstrating Synergy of TransFORM Body

with Cryolipolysis Procedure

• Double-blind randomized controlled trial

• N=11

• Patients treated on both arms with cryolipolysis

• Randomized to treatment BID for 3 months with TransFORM Body or bland

moisturizer (with extension to 6 months)

• Greater fat loss seen at 8, 12 and 24 weeks on TransFORM Body side

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Week 12

Left Arm –

TransFORM Body

with TriHex

Technology

Greater Reduction in Contour Using TransFORM Body

Post-Cryolipolysis

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Δ = -18.12% Δ = -17.85%

Subject courtesy of Amir Moradi, MDNote: linear distance taken from landmark 1 to landmark 2. The delta between baseline measurement and follow up measurement is then calculated.

Baseline Week 8

Right Arm –

Bland Moisturizer

Δ = -11.43% Δ = -13.11%

86%

75%83%

14%

25%17%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

8 Weeks 12 Weeks 24 Weeks

TransFORM Body Arm Moisturizer Arm

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Canfield Photographic AssessmentReduction in Vertical Arm Size

*p<0.05*p<0.05

Side with greater reduction from Baseline

Cryolipolysis subject (Abdomen): Accelerated volume reduction

on the side with TransFORM Body (Subjects’ Right Side)Volume calculated by Quantificare 3D Imaging

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Photo courtesy of Suzanne Kilmer, MDFemale – Subject courtesy of Amir Moradi, MD

Treatment & Regimen: Subject received one session of Cryolipolysis fat reduction procedure on both sides of the lower abdomen. Subject followed-up treatment with a split abdomen regimen that included the Topical with TriHex product on the subject’s left side and no topical treatment on the subject’s right side (only the procedure treatment).

Imaging Equipment & Analysis: The case study photos were taken with the QuantifiCare LifeViz® Infinity camera and software imaging system. 3D photos reveal volume and contour changes. Volume changes are calculated in mL. The volume map changes are highlighted with blues that represent volume reduction and reds that represents volume increase.

R = -153mL vs L = -76mL

Control

TransFORM Body

Treatment

12 Weeks

Post Treatment

Baseline

0.10.3

0.60.8 1.0

1.3 1.4

2.02.3

3.03.2

4.3

5.1

0.0

0.5

1.0

1.5

2.0

2.5

3.0

3.5

4.0

4.5

5.0

5.5

Mil

lio

ns

Procedure Anti-aging

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Sales by Product Line by Quarter *(2016: $1.8M; 2017: $5.7M; 2018 : $12.8M)

*Note: Annual Sales

# of Account Partners Ramping Quickly

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Will reach over 1,600 accounts in 2019 and 2,400 in 2020

62121

174246

308385

457520

608

738

869

1,026

1,176

0

200

400

600

800

1,000

1,200

1,400

# A

cco

un

ts

Total Physician Accounts by Quarter

Our Vision for the Future

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Become the

#1 Company in the

Physician-dispensed

Skin Care Space

Our 5-year Plan:

Surpass $100M

in Sales

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