master in biochemistry and molecular and cellular biology...
TRANSCRIPT
Master BBMC
Strengths
Organization
-Master1
-Master2
Master 120, organized by the Department of Biology and the Faculty of Medecine
This master is intended for students having a diploma of « Baccalauréat » in biology, biomedical sciences or veterinary sciences, who want:
to understand biological processes at the levels of cells and molecules, in physiological and pathological conditions
to study the living world in its whole complexity: - from genes to systems - from bacteria to humans
to conceive and develop research projects, to interprete and publish
scientific results
Master in biochemistry and molecular and cellular
biology (BBMC)
Master BBMC
Strengths
Organization
* Master1
- Mandatory
courses
- Modules
- Practi.
- Thesis
* Master2
Master 1
Months
Mandatory courses: • Advanced techniques for cellular and
molecular biology • Evolution • Communication skills • Humanities
Modules: 22 modules to be chosen (of 22h each) : students chose 10 out of the 22. These modules benefit from the expertise of reknown researchers. The program allows all the possible combinations.
1st year
Months 5
Eva
lua
tion
s
Formation to handle laboratory
animals 4 ECTS
Practical
courses
2 ECTS
Thesis ("mémoire") 15 ECTS
61 2 3 49
Eva
lua
tion
s
Man
datr
ry c
ours
es
9 EC
TS
Modules 30 ETCS
10 11 12
Master 1 : modules
Pharmacogénétique
Diagnostic moléculaire
Etapes du dév. des médicaments
Organismes modèles et développement
Cellules souches et différenciation
Biogenèse et dysfonctionnement des organites
Environnement cell. et physiopath. cellulaire
Cancer
Inflammation
Maladies liées au trafic intracellulaire
Relations hôte-pathogènes
Vieillissement normal et pathologique
Pathologie vasculaire
Génomique structurelle et fonctionnelle
Biologie intégrée des maladies métaboliques
Dynamique génétique : questions de survie
Analyse des données biologiques à haut débit
Aspects tech. et philo. des manipulations génétiques
Evolution moléculaire et adaptation
Glycobiologie
Structure et fonction des protéines
Biotechnologies
Modules Filières
This
« filière » is
entirely
taught in
English
Master BBMC
Strengths
Organization
* Master1
- Mandatory
courses
- Modules
- Practi.
- Thesis
* Master2
1st year
Months 5
Eva
lua
tion
s
Formation to handle laboratory
animals 4 ECTS
Practical
courses
2 ECTS
Thesis ("mémoire") 15 ECTS
61 2 3 49
Eva
lua
tion
s
Man
datr
ry c
ours
es
9 EC
TS
Modules 30 ETCS
10 11 12
Master 1 : integrated practical courses
Months
Integrated practical courses: One whole real research project, taking place in different labs during 2 weeks, allowing to conceive and perform the experiments in order to answer a biological question: how does NF-kB regulate gene expression ? Ex : to chose an amino acid to be mutated
to mute the gene of interest in an expressing vector
to transfect the plasmid in mammalian cells
to study the influence of the mutation on the cell responses
Master BBMC
Strengths
Organization
* Master1
- Mandatory
courses
- Modules
- Practi.
- Thesis
* Master2
Master 1 : Formation for the handling of laboratory animals
Formation for the handling of laboratory animals: Legally mandatory for all the researchers who handle animals during their research project, even during the master thesis with an exam and a legal certificate
1st year
Months 5
Eva
lua
tion
s
Formation to handle laboratory
animals 4 ECTS
Practical
courses
2 ECTS
Thesis ("mémoire") 15 ECTS
61 2 3 49
Eva
lua
tion
s
Man
datr
ry c
ours
es
9 EC
TS
Modules 30 ETCS
10 11 12Months
Master BBMC
Strengths
Organization
* Master1
- Mandatory
courses
- Modules
- Practi.
- Thesis
* Master2
Master BBMC
Atouts
Organisation
* Master1
-Cours oblig.
-Modules
-TP intégrés
-Mémoire
* Master2
-Mémoire
-Cours
-Stage
Master 1 et 2 : master thesis
Master thesis : -long (from February Master1 to December Master2) -in excellent internationally recognized research labs from the Department of Biology, the Department of Veterinary Sciences or the Faculty of Medicine -it is the student who choses his/her project and his/her host lab -Full-time research training
Training to be an expertised researcher
1st year
Months 5
Eva
lua
tion
s
Formation to handle laboratory
animals 4 ECTS
Practical
courses
2 ECTS
Thesis ("mémoire") 15 ECTS
61 2 3 49
Eva
lua
tion
s
Man
datr
ry c
ours
es
9 EC
TS
Modules 30 ETCS
10 11 12Months
Master BBMC
Strengths
Organization
* Master1
- Mandatory
courses
- Modules
- Practi.
- Thesis
* Master2
Master BBMC
Atouts
Organisation
* Master1
-Cours oblig.
-Modules
-TP intégrés
-Mémoire
* Master2
-Mémoire
-Cours
-Stage
Master 1 et 2 : Master thesis - examples
- Study of the effects of cycling hypoxia on tumor-
associated macrophages and endothelial cells
- Implication of MAGE b1/b2 in tumorigenesis
- Implication of NO and endothelin in aristolochic acid-induced nephrotoxicity in obese rats
- Correlation of genome evolution and invasiveness in Corbicula
- Study of the adaptive response of bacteria exposed to copper, a
double-edge sword
- Study of the molecular mechanisms controlling alpha-proteobacteria development
- Characterization of metabolic adaptation capacity of Brucella
Master BBMC
Strengths
Organization
* Master1
- Mandatory
courses
- Modules
- Practi.
- Thesis
* Master2
- Thesis
- Courses
- Internship
Master BBMC
Strengths
Organization
* Master1
• Master2
• Thesis
- Courses
- Internship
Master 2 : Courses
Winter schools: 1 week on a subject (ex proteomics) with courses, seminars by researchers in the field and practical formations. To be chosen among the 10 winter schools organized by different universities.
Courses to be chosen (2): • parasitology • programmation for
biologists • clinical biology • cell and gene therapies • analysis of organ
functions in animals • anti-cancer therapies • philosophy of life
sciences
Courses to be chosen (2):
• management
• intellectual property,
patents and research
valorization
• industrial utilization of
animal and plant cells
• human ressource
management
• in vitro fecondation
2nd year
Months
Winter school 4 ECTS
2 3 4 5 6
Thesis ("mémoire")
14 ECTS
Cou
rses
at
choi
ce
6 EC
TS
Stage 30 ECTS
Courses
at choice
4 ECTS
Eva
lua
tion
s
9 10 11 12
Eva
lua
tion
s
1
Master 2 : Internship
Finalité approfondie: Internship in a research laboratory, out of UNamur, mainly abroad
Finalité spécialisée:
Internship in a private company, in a spin off or in an administration, in Belgium or abroad
Finalité didactique:
Courses and stages in secondary schools (= AESS or « agrégation »)
2nd year
Months
Winter school 4 ECTS
2 3 4 5 6
Thesis ("mémoire")
14 ECTS
Cou
rses
at
choi
ce
6 EC
TS
Stage 30 ECTS
Courses
at choice
4 ECTS
Eva
lua
tion
s
9 10 11 12
Eva
lua
tion
s
1
Master BBMC
Strengths
Organization
* Master1
• Master2
• Thesis
- Courses
- Internship
Master 2 : Internship in private companies
In Belgium:
Rixensart
Wavre
In Europe:
Master 2 : Internships in private companies - examples
(Leuven) Biopharmaceutical company focused on cell therapy
STAGE
STAGE
STAGE
To test the effect of human serum on the expression patterns of distinct marker genes of human chondrocytes in 3D culture
Expression profiling and functional analysis of genes associated wth osteoarthritis
Development of new tests allowing to evaluate the efficacy of skin cosmetic products
(Les Isnes) Production and commercialization of reconstituted epidermis for in vitro tests
Master BBMC
Strengths
Organization
* Master1
• Master2
• Thesis
- Courses
- Internship
Master 2 : Research internship
Financement via ERASMUS mobility grants
Master BBMC
Strengths
Organization
* Master1
• Master2
• Thesis
- Courses
- Internship
Master 2 : Research internship - examples
Harvard Medical School, Boston, Massachusetts, USA
Identification of novel regulators of breast cancer progression using genomics-based screening platforms
STAGE
Yale University, Connecticutt, USA
Localisation of proteins inside bacterial cells STAGE
Barts Cancer Institute (Queen Mary University), London, UK
Implication of avb6 integrin in epithelial cancers STAGE
Institute of Signalling, developmental biology and cancer research, University of Nice, France
Regulation of intracellular pH in cancer cells: involvement of carbonic anhydrases
STAGE
Master BBMC
Strengths
Organization
* Master1
• Master2
• Thesis
- Courses
- Internship
Master BBMC
Strengths
Organization
• Master1
• Master2
Conclusions
Conclusions
THE WHOLE FORMATION IS CHOSEN BY THE STUDENT ALL ALONG THE TWO YEAR MASTER •Formation based on strong research labs and expertise •Master co-organized with the Faculty of Medecine orientation in human molecular and cellular biology •Long master thesis (10 months fulltime in a laboratory), insertion in a research team •Internship: professional insertion in a private company or in a research lab abroad
an unforgettable experience to learn science and life often a springboard for a first job
Master BBMC
Strengths
Organization
• Master1
• Master2
Conclusions
Conclusion - jobs
Very complete formation with a professional insertion internship = a real asset to find a job
What is the job of previous BBMC students ?