LAVAN-Roll-outatMHH:Efficient and compliant animal facility management with

modernsoftware.

Dr.NadineHeldheld.nadine@mh-hannover.deMatthiasOttinger(PhD)ottinger.matthias@mh-hannover.de

structure of today‘s talk1. Part:GeneralLAVANintrodurction

n Why MHHchose LAVAN?LAVANadvantages

n LAVANuser interfaces (desktop (projects),animal room (touch))

n How doIfindmy animal related data inLAVAN?

n How doIplace mate requests,euthanisation tasks or transport requests?

n What is important when Iaminthe animal room myself?

2. Part:Focusonexperimentaldocumentation (animals ‘inexperiment‘)

n essentialdocumentation requirements...

n ...to generate reporting for the authorities

3. Part:next steps

www.omikronsystems.com

LAVANis inuse inuniversities,researchinstitutes and industry

www.omikronsystems.com

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Why LAVANfor MHH?

LAVAN

• promotes the lean,efficient and error-free animal facility

• helps us to fulfil legalrequirements and documentation requirements

• is (relatively)easyto use and has low training requirements

• MHHhas more resources to doour core business:doexcellent research

• Because of LAVANwe can already provide higher service levels:

n setting up matings,performing euthanisations (scientist places tasks via

LAVAN),weaning,and more

n e.g.breeding documentation is competely done by LAVANautomatically (no

more paper based documentation required)

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Cloud-Server(Linux)

PostgreSQLdata base

LAVANJAVAwebapplication

HTTPSHTTPS

modernweb-application/access /security:state-of-the-artsoftware

•application and databaseonredundantservers

•automated back-ups todifferentlocation

•production- undQA-system

simplified schematic

Reportingtool

Email-server

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Browsersthat support full LAVANfunctionality

• GoogleChrome

• MicrosoftEdge(comes with Windows10)

• AppleSafari

• Opera

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LAVANintegrates important aspects and processes of our datamanagement to promoteefficent work flows

animal welfare/licenses(TVA)• license management• animal numbers• projects linked to licenses• prospective/acutal severity

animal location• unit,room,rack,cage• cage occupancy• animal transfers between

cages are tracked

breeding management• easy,transparent• species-specific logic• promotes efficient

breeding

strains/genotyping• detailled strain info• e.g.genetically modified,

stressed,cryostock• genes/alleles

billing• automated reports

with animal and cagenumbers

• perworking group androom

experimentaldocumentation• protocols• tasks• easydocumentation• GLP-ready

communication/tasks• realtime• documentation of allrelevant

events• user with specific access rights

vet module• sickanimals• abnormalanimals• treatments...

With LAVANwe always know where animals are and whattasks are due

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LAVANfunctional interfaces

• admin• projects (desktop)• animal room (touch)

• leading principle:allwork with animals is documentedimmediately when work is performed!

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unique animal code is automatically generated

permanent

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LAVANproject definition

• ‚projects‘inLAVAN:group of animals for aspecific purpose– projects without license (husbandry,breeding-no license required)– projects with license (experiment,breeding-with license)

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LAVANanimal status ‘inexperiment‘

• inprojects that require alicence experimentalanimals get thestatus ‚inexperiment‘by the scientist– afterthat,these animals can only depart as §4or §7animals dependent

onthe linked license

– §4and §7animals can only depart from projects with linked license.Departed animals are then counted onthat license for reporting.

– §7animals (experimentalanimals)mustget aseverity assessent of actualseverity atleastonce (usually by the scientist):mild/moderate/severe

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logic linkfrom licence to project to animallicense (e.g.§7only)

• project(s)is(are)linked toone license

• animals are always inexactly oneproject

• experimentalanimals get the status‚inexperiment‘when theexperiment starts

• documentation of animalcontrols by documentingseverity assessment

• departure with departurereasons according to category§7

anim

alwillbecoun

tedon

tothelinkedlicen

se

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based onthese data LAVANgenerates comprehensivereports for reporting to the authorities

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change of documentation from cards to LAVAN

• from cards (white ‚Tierschutzkarten‘)and manual counting tocomplete reporting viaLAVAN

• inthe year of transition numbers have to be aggregated byhand

• very important:exact date of transition for individualresearchgroup– until this date:old system (Tierschutzkarten)– from that date on:correct and complete registration of departures of

§4and §7animals viaLAVANfrom exerimental projects only

LAVAN- DIETierhaus-Management-Software

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to be able to document inreal-timeinthe animal room andto get access to your animal data you need access to LAVAN

• Laptopsare possible• recommendation for animal room:

– AppleiPad(current generation),cheapest version ok– cost:approx.Euro370,-– please contact BrankoJandric for offer (jandric.branko@mh-

hannover.de;Tel3708)– onthe MHHorder:‚iPadfürLAVAN‘– once the device arrived:

• go to BrankoJandric• needs to be inventarized atMHH• WLANaccess atZTL

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Nextsteps

• for allscientific groups until introduction until endof 2017• scientific groups that already have allanimals inLAVAN:no

change• scientific groups that have no animals/part (e.g.breeding)of

their animals inLAVAN:roll-outfor allanimals incl.experimentalanimals

• for each scientific group/or department:main contactperson atZTLincharge.Thisperson either has contactedyour group already of willdosovery soon.

• always necessary (please prepare inadvance):1. Inwhich rooms are you animals?2. Listperroom:strains/lines with labname and ZTL-strain code3. Listof actively used licenses (TVAs)(with authorisation number,e.g.17/1234)4. Listwith allpersons ingroup that willwork with animals (incl.emailand phone

number).We need this to set up user accounts.

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current contact persons atZTL

• MartinaDorsch:– clarification or novel strain identifiers (ZTL-Codes)– verify strain information and set up strain inLAVAN(M.Dorsch,M.Ottinger,I.Brüsch)

• NadineHeld/AndreaKrüger(Tierschutzbüro):– verify licenses (TVAs)and administrate them inLAVAN

• BrankoJandric:– Hardware/WLAN/iPads– 1.contact person with problems that likely have tecnical reasons,e.g..connectivity issues,WLAN,

(Tel.3708)

• NadineHeld/MatthiasOttinger:– general introductions

• differentpersons:– first contact person during the roll-outprocess for your scientific group– person from ZTLwillcontact your group– coordination indetail for your scientific group/department

• MatthiasOttinger:– coordination– contact me with general questions/issues (Tel.17-3954)

LAVANEinführungamZTL