lara briden endometriosis and pcos...endometriosis and adenomyosis post-pill acne pcos berberine-500...
TRANSCRIPT
PERSONALISED HEALTHCARE.ENHANCED PATIENT OUTCOMES.
LARA BRIDENENDOMETRIOSIS AND PCOS
PRODuCT SuPPORT BOOkLET
NEW ZEALAND | SEPTEMBER 2019
PO Box 19033, Marewa, Napier 4143 • 77 Austin Street, Onekawa, Napier 4110 0800 439 633 • [email protected] • www.fxmed.co.nz facebook.com/groups/fxmed/
Period Repair Manualby Lara Briden, ND
Containing invaluable advice for women of every age and circumstance, and detailing treatments from nutritional supplements to a healthy diet, this book promises to help women change their relationship with their menstrual cycle. Topics include how to come off hormonal birth control, what your period should be like, what can go wrong, how to talk to your doctor and treatment protocols for all common period problems, including PCOS and endometriosis.
Lara’s book has already garnered rave reader reviews because it deals so openly and compassionately with this important aspect of women’s health.
$34.50 (incl GST)
Books available for
purchase from FxMed
CONTENTS By CONDITION
PCOS CORE PRODUCTSInositol Powder 6MegaSporeBiotic 7Magnesium Glycinate Liquid/Capsules 7UltraZin Zinc Capsules 13
InsulIn-resIstant PCOsAlpha Lipoic Acid 1Berberine-500 2Metabolic Xtra 2Inositol Powder 6Magnesium 7
Key Products
Berberine-500 2
CurcumaSorb 3
NAC 900mg 9
Resveratrol 12
Nrf2 Detox 12
Selenomethionine 13
Vitamin A Capsules 13
Ultrazin Zinc Capsules 13
AdditionAl Products
Calcium D-Glucarate 3
Digestion enzymes Ultra with Betaine HCl 4
Bio-Gest 4
Liposomal Glutathione 5
Tri-fortify Gel 5
Megasporebiotic 7
Microbinate 8
Liver-G.I. Detox 8
Siliphos 9
CytoQuel 10
Th2 Modulator 10
endOmetrIOsIs and adenOmyOsIs
POst-PIll aCne PCOsBerberine-500 2Bio-Gest 4Digestion Enzymes Ultra with Betaine HCL 4DIM Detox 4Pantothenic B5 1UltraZin Zinc Capsules 13
InflammatOry PCOsNAC 900mg 9CytoQuel 10Th2 Modulator 10
adrenal PCOsStress B-Complex 1Pantothenic B5 1ADR Formula 6Adrenal 6Magnesium 7
andrOgen BlOCkers Chaste Tree Berry 3DIM Detox 4PMS Soothe (Peony & Licorice combination) 11Super Reishi 11UltraZin Zinc Capsules 13
funCtIOnal testIngDNA Oestrogen by DNA Life 14DUTCH PLUS by Precision Analytical 15
Saliva Hormone Test by Labrix Labs 16Celiac Panel by Doctor’s Data 17
lara BrIden semInar CHartsPCOS Product Chart 18Endometriosis Product Chart 19
PO Box 19033, Marewa, Napier 4143, New Zealand • 77 Austin Street, Onekawa, Napier 4110, New Zealand
AUS 1800 770 904 • NZ 0800 439 633 • [email protected] • www.fxmed.co.nz facebook.com/groups/fxmed/
CONTENTS By INgREDIENT/SuPPORT
Alpha lipoic Acid 1
B vitamins 1
Berberine 2
calcium d Glucarate 3
chaste tree Berry 3
curcumin 3
Digestive Support 4
DIM / Sulforaphane combination 4
Glutathione 5
HPA Axis support 6
inositol 6
Intestinal Permeability 7
Magnesium 7
Microbial support 8
Milk thistle/liver support 8-9
nAc 9–10
NAC /Curcumin / Resveratrol combination 10
Peony & licorice 11
reishi 11
resveratrol 12
Resveratrol/Sulforaphane /Glutathione combination 12
selenium 13
Vitamin A 13
Zinc 13
1
Alpha Lipoic Acid
B Vitamins
Alpha Lipoic AcidSupports healthy glucose metabolism and nerve health
• Alpha lipoic acid is both water and fat soluble which allows it to function in almost any part of the body as an antioxidant.
• Improves insulin sensitivity and boosts glutathione.
• A key component of the metabolic process, alpha lipoic acid produces energy in muscles and directs calories into energy production.
• In addition, it helps maintain healthy glucose metabolism, supports the nervous system and provides nutritional support for healthy liver function.
Suggested use: 1 capsule, 1-4 times daily, with meals.
Pantothenic B5Cortisone support and energy metabolism
• Research Nutrition’s Pantothenic B5 is a pure and hypoallergenic source of vitamin B5 for flexible dosing within focused clinical applications, such as optimising skin integrity and healing, adrenal health and stress resilience, healthy hormone and energy metabolism.
• Especially required for the production of cortisol and cortisone, and may be beneficial for supporting healthy adrenal function and the ability to adequately respond to stress.
• Essential for the production of certain neurotransmitters, such as acetylcholine and melatonin.
• 500mg capsule provides optimum dosing flexibility.
Suggested use: 1 to 6 capsules daily.
Stress B-Complex B complex with extra B5 for adrenal support
• Stress B-Complex contains an optimal balance of essential B vitamins, with extra vitamin B5 to support healthy adrenal and immune function. Healthy adrenal glands play an important role in effectively managing stress.
• Although each B vitamin is chemically distinct, they work synergistically in various biochemical functions throughout the body – including cellular energy production, healthy red-blood-cell formation, and healthy neurological function.
• Pantothenic acid (vitamin B5) serves as the starting material for the synthesis of coenzyme A, which is important for the metabolism of fats and the synthesis of adrenal hormones. Also plays a key role in the formation of acetylcholine, which is needed in the transmission of nerve impulses.
• For stress and HPA axis dysfunction a B vitamin containing Choline and B5 is recommended.
Suggested use: 1 capsule one to three times daily.
• Insulin resistancePCOS
• Adrenal• Post-pill acne
PCOS
• AdrenalPCOS
2
Berberine
Berberine-500 Supports a healthy balance of normal bacteria in the intestines
• Anti-microbial effect against bacteria, fungi, viruses, yeast, protozoans and helminthes.
• Biofilm disruptor activity.
• Eradicate bacterial overgrowth – hydrogenic bacteria.
• Higher amount for maintenance of healthy glucose metabolism.
• Supports healthy lipid levels.
• Provides cardiovascular support.
• Contains 500mg of Berberine HCl per capsule. Evidence to support doses of up to 5g in split doses.
• Supports the reduction in inflammation by sheltering the immune system from the bacterial toxin LPS, repairing intestinal permeability and downregulating pro-inflammatory genes.
Suggested use: 1-2 capsules two times daily. Lara suggests taking for 5-7 days for 8 weeks then stop for 1-2 weeks. Restart 4 days/week depending on what suits your client.
Metabolic XtraSupports healthy insulin function and glucose homeostasis
• Metabolic Xtra is a powerful combination of nutrients that helps support insulin receptor function as well as healthy glucose metabolism.
• Enhances the expression and function of insulin receptors with the natural plant alkaloid berberine - In a randomized placebo-controlled trial involving 116 subjects, berberine provided statistically significant support for glucose, lipid, and triglyceride metabolism.
• Resveratrol supports healthy AMPK and SIRT1 expression to support cellular metabolism and glucose homeostasis.
• Modulates cell signaling for healthy insulin function with patent-pending Zychrome™ chromium dinicocysteinate.
• Supports healthy receptor function and glucose metabolism with alpha lipoic acid.
Suggested use: 1 capsule, 1-3 times daily, with meals.
Supplement Facts
Amount Per Serving
Chromium (as chromium dinicocysteinate) √.......................... 135 mcgBerberine HCl............................................................................ 350 mgAlpha lipoic acid (thioctic acid).................................................. 100 mgResVida® resveratrol (as trans-resveratrol)................................ 20 mg
Other ingredients: Vegetarian capsule (cellulose, water), ascorbyl palmitate, hypoallergenic plant fi ber (cellulose).
√ Zychrome™ brand chromium dinicocysteinate. Zychrome™ is a trademark of InterHealth N.I.
ResVida® is a trademark of DSM
Not to be taken by pregnant or lactating women.
1 capsule, 1-3 times daily, with meals.
Each capsule contains:
• Gram-negative bacteria/LPS• Inhibits NF-kB• Intestinal permeability/SIBO
Endo
• Insulin resistancePCOS
• Post-pill acne • Insulin resistance
PCOS
3
Calcium D-glucarate
Curcumin
Chaste Tree Berry
Chaste Tree BerryProgesterone support
• Provides support for normal menstrual cycle, and a healthy balance of normal levels of female hormones.
• Chaste Tree Berry has dopaminergic activity, has shown to improve the messaging from the brain to the ovaries to improve progesterone production.
• Provides support for a normal menstrual cycle.
• Support for the transition into menopause.
• Supports mood, fluid retention, breast tenderness and promotes ovulation.
Suggested use: Adults take 2 capsules daily in the morning.
CurcumaSorb Clinically studied for enhanced absorption
• CurcumaSorb provides the patented Meriva® curcumin-phosphatidylcholine complex for enhanced absorption and bioavailability. The proprietary phytosome technology combines curcumin and phosphatidylcholine at a 1:2 ratio, promoting resistance to degradation in the digestive tract and efficient absorption across membranes.
• Supports enhanced absorption for joint, tissue and cellular health, digestive and cardiovascular health.
• Shown to support the reduction in size and activity of endometriosis lesions. It downregulates a proinflammatory transcription factor called NF-kappaB thereby accelerating healthy cell death or apoptosis in the lesions. Inhibits angiogenesis or the growth of new blood vessels.
Suggested use: 2 capsules, 1-3 times daily, between meals.
Calcium D-GlucarateSupports healthy hormone metabolism • Enhances liver detoxification - promotes recycling of
environmental toxins and hormones back into the liver, aiding in their elimination from the body.
• Supports glucuronidation, an important liver detoxification pathway - Calcium D-glucarate helps assure this elimination process occurs uninterrupted.
• Other applications include the maintenance of already normal cholesterol levels and support for healthy hormone metabolism.
• Supports healthy estrogen metabolism by binding to estrogen in the liver and deactivates it. Also inhibits beta-glucuronidase which is the enzyme made by the gut bacteria that causes estrogen to be reabsorbed.
Suggested use: 1 capsule three times daily.
• Additional productEndo
• InflammatoryPCOS
• Inhibits NF-kB• Supports Glutathione and
T-reg cells• Stimulates NrF2
Endo
• Androgen blockerPCOS
4
Digestive Support
DIM/Sulforaphane Combination
Bio-Gest Broad spectrum digestive aid
• For individuals needing more than HCI – a blend of hydrochloric acid (HCI), pepsin, pancreatin and ox bile.
• Promotes digestion of proteins, carbohydrates, and fats.
• Ox bile added to promote fat digestion.
• Benefits individuals with occasional indigestion.
Suggested use: 1-2 capsules with each meal.
Digestion Enzymes Ultra with Betaine HCl Blend of vegetarian digestive enzymes to support digestion
• High-strength mixture of betaine HCl with vegetarian enzymes to support enhanced protein, carbohydrate, fat, fibre and dairy digestion.
• A broad-spectrum combination of enzymes support optimal activity across a wide pH range.
• Supports optimal gastric pH with betaine HCl, important for the enhanced digestion of protein and other nutrients to support daily wellness and neurotransmitter synthesis.
• Facilitates the normal breakdown of proteins, peptides, fats, polysaccharides and disaccharides.
Suggested use: 2 capsules, with each meal.
DIM DetoxHealthy estrogen metabolism
• DIM Detox provides powerful support for detoxification and cellular health by promoting healthy cell cycle function and hormone metabolism.
• Supports phase II detoxification.
• Provides antioxidant support for cellular protection.
• Contains BioResponse DIM®, Sulforaphane, Calcium d-glucarate, Lignans, NAC, Milk thistle, L-Methionine, Glycine, alpha lipoic acid and Taurine.
Suggested use: 2 capsules daily, with meals
• Post-pill acnePCOS
• Additional products – Digestive support
Endo
• Additional products – Digestive support
Endo
• Post-pill acnePCOS
• Post-pill acne• Androgen blocker
PCOS
5
glutathione
Liposomal Glutathione Supports antioxidant defenses and detoxification in an innovative liposomal form
• Liposomal Glutathione is an antioxidant formula designed to protect and support cellular function.
• Purified phosphatidylcholine delivery system offers natural liposomal formation due to the hydrophobic and hydrophilic nature of phospholipids. Liposomal form protects glutathione bonds from the degradation that can occur in digestion.
• Supports liver health and detoxification, promotes p450 phase II conjugation pathways in the liver to support detoxification.
• Glutathione is found in virtually every cell of the body and plays a critical role in protein synthesis, enzyme function, transport, and cell maturation. Optimal levels of glutathione have been associated with physical and mental health, protects the body from free radicals to support cellular function and homeostasis.
Suggested use: 1 softgel capsule, 1-2 times daily, with meals.
Tri-Fortify GelMajor intracellular antioxidant in a liposomal delivery system
• Enhances antioxidant action - glutathione is a tri-peptide composed of the three amino acids: L-glutamic acid, L-cysteine and L-glycine. It is known as the master antioxidant because it recycles other antioxidants, such as vitamins C and E.
• Promotes detoxification – supports the liver by removing chemicals that are foreign to the body such as drugs and pollutants.
• Supports the immune system – plays a critical role in the function of WBCs, many chronically ill patients have depleted levels of glutathione.
• The unique liposome structure allows it to combine effectively with the body’s natural fluids and penetrate its protective membranes, bypassing the digestive system and directly entering the blood stream. By avoiding the process of digestion, nutrient absorption and utilization is much quicker and more complete.
• GMO Free and heat stable at room temperature.
Suggested use: 1 teaspoon daily, hold under tongue for 30-60 seconds and then swallow. Additional doses may be taken before other meals. Tri-Fortify™ effectively encases the glutathione, producing a pleasant naturally flavoured gel that you squeeze onto a spoon and enjoy. No need to mix with juice or water.
• Normalises T-reg cell activityEndo
• Normalises T-reg cell activityEndo
6
HPA Axis Support
Inositol
ADR FormulaComprehensive adrenal support formula
• ADR Formula® offers broad-spectrum nutritional support to promote adrenal gland function.
• This formula combines the whole adrenal and adrenal cortex with a mixture of herbal extracts that nutritionally supports the production of certain adrenal hormones and maintains a healthy immune response.
• Whole adrenal and adrenal cortex are included for their potential to nutritionally support the adrenal gland.
• Panax ginseng and Eleutherococcus senticosus, or eleuthero, are used primarily as adaptogens, supporting overall health by a wide range of physical, chemical, and biochemical factors.
Suggested use: 1 capsule daily between meals.
AdrenalGlandular support for healthy adrenal function
• Adrenal is a supplement designed to provide support to your adrenal glands and support HPA axis.
• Supports healthy cortisol levels.
• Contains whole adrenal and adrenal cortex herbal extracts shown to nutritionally support the adrenal gland.
Suggested use: 2 capsules, 1-2 times daily, between meals.
Inositol Powder Supports ovarian function & mood
• Inositol is formulated to support healthy central nervous system function. As a result, Inositol may lessen mild and occasional nervous tension and support healthy mood, emotional wellness and behaviour.
• Inositol is a component of the B-complex family. Myo-inositol is the primary form of inositol found in the central nervous system. It plays an important role in cell membrane formation and serves as part of the phosphatidylinositol secondary messenger system, supporting serotonin, norepinenephrine and cholinergic receptor function.
• Research also suggests that myo-inositol may help to support healthy ovulatory activity, ovarian function, and reproductive system function.
• Convenient powder formula for easy dispensing.
Suggested use: 2 scoops 1-2 times daily with or between meals.
• AdrenalPCOS
• AdrenalPCOS
• Core product• Insulin Resistance
PCOS
7
Intestinal Permeability
Magnesium
MegaSporeBiotic100% Spore-based broad spectrum probiotic
• Naturally designed to survive digestion, colonizes, and increases microbial diversity in the gut, reduces systemic inflammation and provides immune support.
• Strong enough to withstand broad-spectrum antibiotics.
• Increases butyrate production, which has been shown to reduce the inflammatory process in the gut.
• Contains Bacillus Coagulans, B.Indicus (HU36), B.Licheniformis, B.Subtilis (HU58) and B.Clausii. 5-year shelf-life, does not require refrigeration.
• Microbiome Labs recommend using HU58™ in conjunction with MegaSporeBiotic when treating a patient with SIBO.
Suggested use: 2 capsules daily. Refer to titration schedule in Microbiome catalogue for dosage.
Magnesium Glycinate Capsules Muscle function, mood and calming support
• Magnesium activates the enzymes necessary for a number of physiological functions, including neuromuscular contractions, cardiac function, and the regulation of the acid alkaline balance in the body.
• Magnesium is also a nutritional cofactor for serotonin.
• This vital mineral also helps utilize B-complex vitamins, vitamin C and E.
• Magnesium helps activate neurotransmitters that are responsible for calming the body and the mind.
• May help prepare your body and mind for sleep, by calming the nervous system.
• It also regulates the hormone melatonin, which guides sleepwake cycles in your body.
Supplement FactsAmount Per Serving
Each vegetarian capsule contains:
Other Ingredients: vegetarian capsule (cellulose, water), ascorbyl palmitate
Magnesium (as magnesium glycinate) ................................120 mg
Magnesium Glycinate LiquidHighly absorbable form in a great tasting liquid
• Magnesium glycinate is a highly absorbable form of magnesium chelated to two molecules of the amino acid glycine. Less likely to cause gastrointestinal symptoms and reduces the laxative effect. Glycine is a calming amino acid for the body and mind. Recommended for stress and muscle relaxation.
• Calms the nervous system, supports healthy inflammation levels and stabilises serotonin receptors.
• The liquid is very palatable and contains purified water, grape juice concentrate, malic acid, xylitol, natural glycerin, apple juice concentrate, natural pomegranate, orange, and other natural flavours and potassium sorbate.
• Contains 165mg of magnesium glycinate per serve (2 teaspoons)
Suggested use: 2 teaspoons daily.
• Core Product• Adrenal• Insulin Resistance
PCOS
• Core Product• Adrenal• Insulin Resistance
PCOS
• Core ProductPCOS
• Intestinal permeability/LPSEndo
• Inhibits NF-kBEndo
• Inhibits NF-kBEndo
Suggested use: 1- 4 capsules daily, in divided doses, with meals.
8
Microbial Support
MicrobinateSupports a healthy response to microbial challenges
• Microbinate™ combines nature’s most potent and well researched nutrients into one formulation.
• Contains well-researched stabilized Allicin, Oregano extract (30% carvacrol), Monolaurin, Olive leaf extract, and CurcuWIN™ turmeric extract.
• Microbinate™ is designed to promote the body’s healthy response to microbial challenges, internally and externally.
• Supports normal skin health and healthy inflammation levels.
Suggested Use: 1 capsule twice per day for the first week, and two capsules twice per day in week two and beyond. For optimal results, take away from meals.
Liver-G.I. DetoxSupports hepatic and gastrointestinal detoxification
• Enhances phase II detoxification enzymes, supporting glutathione synthesis and promoting gastric, colon and liver cell function.
• Antioxidants NAC and Alpha Lipoic acid help boost tissue glutathione levels.
• Glutamine helps to maintain healthy intestinal integrity, ensuring proper nutrient utilization while limiting the amount of toxins that pass through the intestinal barrier.
Suggested use: 2 capsules daily, with a meal.
Milk Thistle/Liver Support
• Gram-resistant bacteria• SIBO
Endo
• Additional product• Stimulates NrF2
Endo
9
Milk Thistle/Liver Support
NAC
NAC 900mg Supports cellular antioxidant defense system
• N-Acetyl-l-Cysteine (NAC) provides cellular antioxidant and anti-inflammatory properties.
• Precursor to Glutathione (GSH) which is the body’s primary antioxidant and immune regulator.
• NAC is a free radical scavenger that supports glutathione levels in tissues and may protect tissues from peroxidation generated by heavy metals.
• Research shows NAC raised brain GSH and reverses models of GSH depletion.
• Modulates glutamate – reducing impulsivity, addiction and cravings, and has a beneficial effect on reducing anxiety.
• Plays a role in heavy metal detoxification.
• Promotes healthy lung tissue.
Suggested use: 1-2 capsules daily, between meals.
Siliphos• A well-absorbed, well-researched form of milk thistle
• Siliphos combines a flavonoid from milk thistle (silybin) with phospholipids to form a well-absorbed complex. It offers liver-protective benefits and helps maintain normal levels of glutathione.
• Milk thistle contains multiple constituents with strong antioxidant activity that can protect liver cells from free radical damage, strengthen liver cell membranes, and help maintain the liver’s built-in antioxidant system – glutathione and superoxide dismutase (SOD).
• Silybin, normally a water-soluble flavonoid, is converted into a lipid-soluble compound by complexing it with phospholipids, such as phosphatidylcholine, to make a phytosome. The phytosome preparation allows for better absorption of this liver-protective flavonoid into liver cell membranes. Phosphatidylcholine helps repair and replace liver cell membranes.
• Silymarin has been shown to help maintain the liver’s normal inflammatory response to liver-toxic compounds. Of the three flavonoids that comprise silymarin, silybin predominates and is the most biologically active of the three.
Suggested use: 1 capsule two to three times daily.
• Additional product – Stimulates NrF2
Endo
• InflammatoryPCOS
• Inhibits NF-kB• Immune precursor to Glutathione
Endo
10
NAC
NAC/Curcumin/Resveratrol Combination
Th2 ModulatorHelps to modulate the Th2 immune response and maintain Th1/Th2 balance at the cellular level• Part of the PureResponse™ Immune Protocol for healthy
immune balance and function. Th2 Modulator is designed to support healthy Th1/Th2 balance and mucosal health. Modulating Th2 status helps to maintain Th1/Th2 balance.
• Offers support for self-tissue response, Th2 modulation may be indicated when addressing immune balance in the sinus, respiratory, urinary, and intestinal tracts.
• Contains a blend of N-acetyl-l-cysteine (NAC), quercetin, perilla seed and astragalus extracts.
• Th2 response is affected by stress, aging, and cytokine changes resulting from metabolic, hormonal, physiological, and environmental factors. The product helps support healthy modulation of Th2 cytokines, and eosinophil and mast cell activity. It also helps maintain healthy modulation of mucosal immune responses to environmental factors.
• Perilla supports cytokine homeostasis of GI mucosal tissue. N-acetyl-l-cysteine (NAC) offers mucolytic properties and promotes tissue levels of glutathione – a key component of the antioxidant defense system – to support the body’s natural defense system. Quercetin is known for its antioxidant activity and immune support properties, including support for Th1/Th2 balance and cytokine balance. Astragalus may help modulate the relationship between Th1 and Th2 cytokines.
Suggested use: 2 capsules, 1–2 times daily, between meals.
CytoQuelPromotes healthy cytokine activity
• The healthy body balances pro-inflammatory cytokines with anti-inflammatory cytokines.
• However, if these pro-inflammatory cytokines, (TNF-α), and (NF-kβ) continue in the “on position” and inflammation levels remain high, adverse health may result.
• CytoQuel helps promote balanced cytokine activity restoring healthy inflammation levels.
• Contains NAC, CurcuWIN™ turmeric extract, Black tea extract, DeltaGold® Tocotrienols and Resveratrol.
Suggested use: 1 capsule per day with a meal for the first week, and 3 capsules per day with a meal in week two and beyond. They may be taken at the same meal or spread amongst your meals.
• InflammatoryPCOS
• Additional Product• Immune function/mast cells
Endo
• InflammatoryPCOS
• Additional Product• Inhibits NF-kB• Stimulates NrF2
Endo
11
Peony & Licorice
Reishi
PMS SootheMenstrual Cycle Support
• PMS Soothe™ is a comprehensive blend of Native American and Chinese herbs traditionally used to provide balance and support for a healthy menstrual cycle, reproductive health and common premenstrual complaints.
• This tradition-based, multi-herb formula combines “female herbs” and traditional tonics that have been chosen by means of clinical observation for their complementary and compounding effects.
• Chaste Berry Extract (Vitex angus-castus) has been used for centuries to support women with hormone-related gynecologic complaints. Modern research has validated this traditional use by showing that various preparations of chaste berry demonstrate positive effects in women with premenstrual syndrome (PMS).
• Contains a combination of Chastetree, Dandelion, Dong Quai extract, Parsley, Bupleurum, Tangerine, Peony, Ginger, Red Raspberry and Licorice extract.
Suggested use: 2 capsules daily.
Super ReishiSupports immune and optimal health
• Super Reishi is a high grade quality extract which contains water-soluble polysaccharides (β-glucans) and also fat-soluble triterpenes in order to achieve the maximum range of beneficial constituents.
• Researchers have found various bio-active constituents which have a wide range of actions including: Anti-viral, anti-bacterial and boosts immune function, (specifically natural killer cells, macrophage and interferon).
• Cardiovascular support, lowers blood pressure and serum cholesterol, and protects the heart.
• Research has also demonstrated possible usefulness for allergies, bronchitis, cancer, HIV, inflammation, liver and radiation protection. Recent studies show it may also help maintain a healthy nervous system, HPA axis support and has an anti-inflammatory, anti-allergenic action.
• Inhibits 5-alpha reductase.
Suggested use: 4 tablets once daily or 2 tablets twice a day, after a meal.
• Androgen blocker• Peony/Licorice
PCOS
• Androgen blocker• Reishi
PCOS
12
Resveratrol/Sulforaphane/glutathione Combination
Resveratrol
Nrf2 DetoxAntioxidant and anti-inflammatory support
• Nrf2 Detox is a three-ingredient detox formula designed to help stimulate detoxification and support antioxidant defenses.
• Supports detoxification processes in the liver and promotes proper enzyme function, transport, and cell maturation.
• Down regulates damaging cytokines i.e. NF-κB.
• Activates the Nrf2 pathway, which regulates the production of glutathione and superoxide dismutase (SOD).
• Contains Broccoli (Brassica oleracea italica) sprout concentrate, sulforaphane, Setria® glutathione (reduced form), and ResVida® resveratrol (as trans-resveratrol).
Suggested use: 1 capsule, 1-3 times daily, with meals.
ResveratrolSupports cardiovascular, cognitive and cellular health
• Resveratrol is a compound that promotes cardiovascular health through its antioxidant action.
• Pure Encapsulations’ Resveratrol is derived from one of the richest known sources, Polygonum cuspidatum, a herb utilized for centuries.
• Resveratrol is a compound often associated with the health benefits of red wine, because of its antioxidant and cardioprotectant properties. It promotes cardiovascular health through its antioxidant action and its ability to promote healthy platelet function and maintain healthy arachidonic acid metabolism.
• Shown to support the reduction in inflammatory cytokines and inhibits angiogenesis. Also downregulates aromatase, which is an enzyme that makes estrogen.
Suggested use: 1-5 capsules daily, with or between meals.
• Inhibits NF-kB• Stimulates NrF2
Endo
• Inhibits NF-kB• Stimulates NrF2• Immune function
Endo
13
Vitamin A
Zinc
Selenium
Vitamin A Capsules Supports the body’s natural defence system
• Vitamin A from cod liver oil and palmitate to support cellular health, immune function, and healthy vision.
• Vitamin A is essential to the healthy functioning of a number of biological processes, including vision, growth, reproductive function and the body’s natural defence system. It also supports healthy maintenance of skin and mucous membranes.
Suggested use: 1 capsule daily, with a meal.
Selenomethionine An amino acid bound form of selenium
• Selenium is an important antioxidant mineral. A cofactor for SOD and glutathione function – important “built-in” antioxidants in the body.
• Selenomethionine contains 150 mcg of selenium bound to the amino acid methionine. It is a well-absorbed form of selenium. A significant body of research supports its benefit in numerous situations, including healthy thyroid function and support for oncology patients.
• Selenium is an important trace mineral and a constituent of the antioxidant enzyme glutathione peroxidase, which is necessary for neutralizing the free radical, hydrogen peroxide, as well as other lipid peroxides (oxidized fats).
• Selenium’s beneficial role is not limited to its antioxidant function; it is also necessary for conversion of the thyroid hormone T4 (thyroxine) to active T3 (triiodothyronine). Selenium also appears to exert important positive effects on normal cell function and cell development.
• Selenium is anti-inflammatory and having sufficient selenium has been correlated with a reduced risk of endometriosis. Modulates and normalises the immune system and is essential for the production of progesterone.
UltraZin Zinc Enhanced-absorption and bioavailable zinc
• Exclusive first to market among professional brands Sucrosomial® zinc utilizes an innovative microencapsulation technology to enhance the absorption and bioavailability of zinc by creating a phospholipid bilayer around the mineral similar to a liposome, increasing solubility and absorbability.
• The phospholipid bilayer microencapsulation technology protects the mineral in the gastrointestinal lumen, increases dissolvability, and easily crosses membranes.
• Zinc plays a key role in numerous physiological functions, including nutrient metabolism, energy production and tissue production and repair. Promotes immune defences, enhancing healthy immune cell proliferation, activation and function.
• Zinc has shown to inhibit prostaglandins and inflammation.
Suggested use: 1 capsule daily, with or between meals. Zinc is best with food as can cause nausea on empty stomach.
Suggested use: 1 capsule daily.
• Immune supportEndo
• Immune supportEndo
• Core product• Androgen blocker• Post-pill acne
PCOS
• Inhibits NF-kB• Stimulates NrF2• Immune support
Endo
14
dna healthDNA Health tests for genetic variations that are known to have a significant effect on health and susceptibility to chronic diseases. (e.g.Methylation, Detoxification, Oxidation etc.).
dna dietDNA Diet is amongst the most comprehensiveand accurate weight-management and bodycomposition related genetic tests available.
dna oestrogenDNA Oestrogen tests for various polymorphisms that have been shown to affect the metabolism of oestrogen and associated disease risks.
dna sportDNA Sport provides insight into an individual’spotential for sporting performance, optimal exercise/training selection, recovery strategies and injury risk.
dna healthDNA Health tests for genetic variations that are known to have a significant effect on health and susceptibility to chronic diseases. (e.g.Methylation, Detoxification, Oxidation etc.).
dna dietDNA Diet is amongst the most comprehensiveand accurate weight-management and bodycomposition related genetic tests available.
dna oestrogenDNA Oestrogen tests for various polymorphisms that have been shown to affect the metabolism of oestrogen and associated disease risks.
dna sportDNA Sport provides insight into an individual’spotential for sporting performance, optimal exercise/training selection, recovery strategies and injury risk.
Other panels available:
Clinical Value Recommended for:• Men or women with a strong family history
of breast, ovarian, colon or prostate cancer
• Women who suffer from oestrogen-dominant conditions such as endometriosis, premenstrual syndrome and uterine fibroid tumours
• Women considering oral contraceptives, hormone replacement therapy or bio-identical hormone supplementation
• Women who are considering in vitro fertilization or who have been diagnosed with oestrogen receptor positive breast cancer
DNA Oestrogen Test Report provides:• The level of impact of any genetic variants
identified
• Polymorphisms in key genes involved in metabolizing oestrogen and related compounds
• Impact of high-risk polymorphisms
• An explanation of their impact on oestrogen metabolism
• Personal risk factors associated with HRT, Oral contraceptives, bio-identical supplementation and in vitro fertilisation
• Appropriate nutritional and lifestyle recommendations to support healthy oestrogen metabolism
FxMed Functional Testing
FxMed Educational Portal offers a range of free webinars from our suppliers to learn more about the testing FxMed offers. To access the educational portal, go to http://education.fxmed.co.nz/ and log in using your customer number for both username and password. If you need any help please contact our customer services team.
See below for examples of relevant webinars you can view online at education.fxmed.co.nz:
For additional testing information, please request FxMed’s Functional Testing Reference Catalogue from Customer Services.
Our Technical Support team offer free test interpretation sessions and can help with treatment suggestions as well. Please make a booking 1-2 days in advance with our team.
optimal health for life
Welcome
to your dna oestrogen report
Date of Birth: Date Reported: Sample Number:
Referring Practitioner:
Welcome to your dna oestrogen reportFrom your buccal swab sample we have used a process called the Polymerase Chain Reaction (PCR), which copies the DNA of your genes many times over so that we can generate sufficient quantities to analyse your genetic material. We then identify unique DNA sequences in some of your genes.
Considerable inter-individual variability has been observed in biological areas that are involved in carcinogen metabolism, metabolism of steroid hormones, and phase I and phase II detoxification. Variations in genes involved in these biological processes help identify a sub-population of women and men with higher lifetime exposure to oestrogens, oestrogen metabolites and other carcinogens. Understanding an individual’s genetic variability will allow for targeted diet, lifestyle and hormone intervention.
Report Sample
08 Jan 1990 DNA000000ZA
Doctor X
07 Mar 2018 00:29
Testing Information: Approximately 80% of breast cancer occurs in women with no family history. Oestrogen affects the function of a number of target tissues and research has shown that an increased lifetime exposure to oestrogen is a strong risk factor in the development of breast cancer.
DNA Oestrogen tests for gene variants that have been shown to have an impact on how oestrogen is processed in the body and if the processing of oestrogen and related compounds is efficient and healthy. The DNA Oestrogen test guides the personalisation of diet, hormone and nutritional supplement recommendations to improve oestrogen metabolism.
DNA OestrogenTests for various polymorphisms that have been shown to affect the metabolism of oestrogen and associated disease risks.
20% off
Offer expires 26/11/19
15
DUTCH PlusThe DUTCH Plus™ takes hormone testing to a whole new level. In addition to sex hormones and their metabolites the DUTCH Complete looks at overall diurnal pattern of free cortisol, and the total and distribution of cortisol metabolites. The DUTCH Plus™ adds the Cortisol Awakening Response (CAR).
• An evaluation of the Cortisol Awakening Response (CAR) is done by measuring salivary cortisol upon waking and then again 30 and 60 minutes later (additional measurements are made around dinner and bedtime).
• Research has shown that this post-waking increase in cortisol (the CAR) is the best way to assess an individual’s stress response and HPA-axis function.
• Six organic acids (OATS) markers are included. Two neurotransmitters metabolites which will offer insights into symptoms such as mood disorders and fatigue, and will be combined with markers for vitamin B12, vitamin B6 and glutathione deficiency.
The DUTCH Plus™ report includes: • Metabolites of Estrogens (10, including E1,
E2, E3, 2-OHE1, 4-OH-E1, 2-OH-E2, 4-OH-E2, 16-OH-E1, 2-methoxy-E1, 2-methoxy-E2)
• Androgens (8, including Testosterone, DHT and DHEA-S)
• Progesterone (2)
• Cortisol (3)
• Melatonin (6OHMS)
• 8-OHdG
• OATs (6)
• The diurnal pattern of Free Cortisol and Cortisone are also provided, including the Cortisol Awakening Response (CAR).
Accession # 00280395 Female Sample Report 123 A Street Sometown, CA 90266
Last Menstrual Period:
Ordering Physician: Precision Analytical
DOB: 1976-01-01Age: 41Gender: Female
Collection Times:2017-04-14 06:05AM (U)2017-04-14 08:00AM (U)2017-04-14 05:05PM (U)2017-04-14 10:10PM (U)2017-04-14 06:00AM (S )2017-04-14 06:30AM (S )2017-04-14 07:00AM (S )2017-04-14 05:00PM (S )2017-04-14 10:00PM (S )
Waking (W) W+30 min. W+60 min. Afternoon Night
10
8
6
4
2
0
Low Range Limit
High Range LimitPatient Values
Saliva Free Cortisol Pattern
(ng
/mL)
Saliva C
orti
so
l
5.1
Estradiol(E2)
1.8 4.5
Hormone Testing Summary
2.8
Progesterone
6.0
20.0
7.7
Testosterone
2.3 14.0
2516
Total DHEA Production
500 3000
5930
Metabolized Cortisol (THF+THE)
2750
6500
See Pages 2 and 3 for a thorough breakdown of sex hormone metabolites
Free cortisol best reflects tissue levels. Metabolized cortisol best reflects total cortisol production.
Sex Hormones
0.2-0.7
(Total Cortisol Production)
0.3-2.0
17.50
Saliva Cortisol Total
9.60
19.30
cortisolmetabolism
(Serum Equivalent, ng/mL)
(Sum of 5 values)
Total DHEA Production
Age
40-59>60
750-2000500-1200
Range20-39 1300-3000
(DHEAS + Etiocholanolone + Androsterone)
value based on urine pregnanediol.
Adrenal Hormones See pages 4 and 5 for a more complete breakdown of adrenal hormones
Key (how to read the results):
Progesterone Serum Equivalent is a calculated
Pre
m
enopausal Rang
e
low limit high limitpatientresult
Postmenopausalrange
The following videos (which can also be found on the website under the listed names along with others) may aid your understanding: DUTCH Plus Overview (quick overview) Estrogen Tutorial Female Androgen Tutorial Cortisol/CAR Tutorial
PLEASE BE SURE TO READ BELOW FOR ANY SPECIFIC LAB COMMENTS. More detailed comments can be found on page 8.
- The patient collected an "Insomnia" salivary sample in the middle of the night. The cortisol result for this sample was 2.10ng/mL (expectedrange 0-0.9). Please see page 4 for cortisol and cortisone results for this sample. The Cortisol Awakening Response (CAR) was 2.99ng/mL (expected range 1.5-4.0) or 69.2% (range 50-160%). See page 5 for more details.
Precision Analytical (Raymond Grimsbo, Lab Director) Female Sample Report Page 1 of 14
3138 Rivergate Street #301C FINAL REPORT CLIA Lic. #38D2047310
McMinnville, OR 97128 01/04/2019 DutchTest.com
NEW optional add on to the DUTCH Plus test (additional charges apply) The new Insomnia Cortisol measurement offers valuable additional information about
cortisol’s potential role in sleep disturbances. NEW to DUTCH testing – Precision Analytical offer new practitioners only 2 tests @ 50% off
(conditions apply)
DUTCH testing was specifically made to be optimally effective for most forms of hormone replacement therapy.
Unique methods are used for improved monitoring of oral progesterone and vaginal hormones.
Patients collect just four or five dried urine samples over a 24-hour period plus five saliva samples. Dried specimen samples are convenient to collect, easy to ship and stable for several weeks.
All Precision Analytical testing methods go through a rigorous and ongoing validation process to verify accuracy, precision, recovery, linearity, etc. in the pursuit of the most accurate and precise techniques available for hormone testing.
20% off
Offer expires 26/11/19
16
• Labrix addresses the clinician’s need for precision and reliability and the scientist’s demand for quality and integrity.
• Labrix is a CLIA certified laboratory. This hard-to-achieve certification is a gold seal of approval on the quality and reproducibility of our testing results.
• Labrix Clinical Services, Inc. is based in the USA and uses state-of-the-art saliva hormone testing techniques.
• Non-invasive way of assessing your patients hormone balancing needs.
• Unlike conventional blood tests, saliva testing represents only the hormones actively delivered to receptors in the body.
• Labrix offers 11 different saliva tests; which covers Estrogen (Estrone (E1), Estradiol (E2), Estriol (E3)), Progesterone (Pg), Testosterone, DHEA, Cortisol and Melatonin.
Labrix LabsLabrix was founded in 2004 by two practising clinicians and is now owned by Doctor’s Data, Inc. The combined strengths of both laboratories, including clinical education and support, and a more comprehensive test menu are now available to providers worldwide.
Adrenal Hormone Report; saliva
Order:SAMPLE REPORT
*SAMPLE REPORT*Client #:12345Doctor:Sample Doctor, MDDoctors Data Inc.3755 Illinois Ave.St. Charles, IL 60174
Patient:Sample ReportAge:57Sex:FemaleBody Mass Index (BMI):N/A
Menopausal Status:Post-Menopausal
Sample Collection Date/TimeDate Collected 10/01/2018AM30 10/01/2018 0800Noon 10/01/2018 1200Evening 10/01/2018 1700Night 10/01/2018 2100Date Received 10/03/2018Date Reported 10/05/2018
Analyte Result Unit L WRI H Optimal Range Reference Interval
Cortisol AM30 11 nmol/L 14.0 - 25.0 5.1 - 30.0
Cortisol Noon 4.7 nmol/L 5.0 - 10.0 2.1 - 14.0
Cortisol Evening 2.5 nmol/L 2.0 - 5.0 1.5 - 8.0
Cortisol Night 0.80 nmol/L 1.0 - 4.0 0.33 - 7.0
DHEA* 181 pg/mL 106 - 300
Cortisol Graph
AM30 Noon Evening Night
nmol
/L
0
5
10
15
20
25
30
35Hormone Comments:
The suboptimal diurnal cortisol pattern and reported symptoms are consistent withevolving (Phase 2) HPA axis (adrenal gland) dysfunction.
Notes:RI= Reference Interval, L (blue)= Low (below RI), WRI (green)= Within RI (optimal), WRI (yellow)= Within RI (not optimal), H (red)= High (above RI)The current samples are routinely held three weeks from receipt for additional testing.*This test was developed and its performance characteristics determined by Doctor's Data, Inc. The FDA has not approved or cleared this test; however, FDAclearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patientmanagement decisions.Methodology: Enzyme Immunoassay
Analyzed by DOCTOR’S DATA, INC. • 3755 Illinois Avenue, St. Charles, IL 60174-2420 USA • LAB DIR: Erlo Roth, MD • CLIA ID: 14D0646470
Hormone Report; saliva
Order:SAMPLE REPORT
*SAMPLE REPORT*Client #:12345Doctor:Sample Doctor, MDDoctors Data Inc.3755 Illinois Ave.St. Charles, IL 60174
Patient:Sample ReportAge:41Sex:FemaleBody Mass Index (BMI):N/A
Menopausal Status:Pre-Menopausal
Sample Collection Date/TimeDate Collected 10/01/2018AM30 10/01/2018 0800Date Received 10/03/2018Date Reported 10/05/2018
Analyte Result Unit L WRI H Reference Interval Supplementation Range**
Estradiol (E2) 1.5 pg/mL 0.5 - 5.0 1.5 - 7.2
Progesterone (Pg) 73 pg/mL 127 - 446 500 - 3000
Pg/E2 Ratio 48.7 200 - 600
Testosterone 35 pg/mL 6.0 - 49 30 - 60
DHEA* 110 pg/mL 106 - 300
Hormone Comments:
Progesterone to estradiol (Pg/E2) ratio and reported symptoms are consistent with progesterone insufficiency (estrogen dominance).Supplementation with topical progesterone to correct this relative deficiency is a consideration. Note: The progesterone level is suggestive of ananovulatory cycle, luteal phase failure or collection outside of luteal phase.
Notes:RI= Reference Interval, L (blue)= Low (below RI), WRI (green)= Within RI (optimal), WRI (yellow)= Within RI (not optimal), H (red)= High (above RI)The current samples are routinely held three weeks from receipt for additional testing.The Pg/E2 ratio is an optimal range established based on clinical observation. Progesterone supplementation is generally required to achieve this level in men andpostmenopausal women.*This test was developed and its performance characteristics determined by Doctor's Data, Inc. The FDA has not approved or cleared this test; however, FDAclearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patientmanagement decisions.**If supplementation is reported then the supplementation ranges will be graphed. The supplementation ranges depicted are for informational purposes only andwere derived from a cohort of adult men and women utilizing physiologic transdermal bioidentical hormone therapy.Methodology: Enzyme Immunoassay
Analyzed by DOCTOR’S DATA, INC. • 3755 Illinois Avenue, St. Charles, IL 60174-2420 USA • LAB DIR: Erlo Roth, MD • CLIA ID: 14D0646470
FxMed Functional Testing
20% off
Offer expires 26/11/19
Tests available include:Comprehensive Plus Panel: Estrone (E1), Estradiol (E2), Estriol (E3), Progesterone (Pg), Testosterone (T), DHEA (D), Cortisol (C) x4 (AM/Noon/Evening/PM)
Women’s Health & Breast Panel: E1, E2, E3, Pg, T, D, C x4 (AM/Noon/Evening/PM)
Comprehensive Hormone Panel: E2, Pg, T, D, C x4 (AM/Noon/ Evening/PM)
Short Comprehensive Panel: E2, Pg, T, D, C x2 (AM/PM)
Basic Hormone Panel: E2, Pg, T, D, C (AM Only)
Adrenal Function Panel: DHEA (D), Cortisol (C) x4 (AM/Noon/Evening/PM)
Diurnal Cortisol Panel: Cortisol (C) x4 (AM/Noon/Evening/PM)
Melatonin Panel: Melatonin (M) x3 (AM/Evening/PM)
ANY 3 HORMONES: Estrone (E1), Progesterone (Pg), Melatonin – AM, Cortisol - AM (Morning), Estradiol (E2), Testosterone (T), Melatonin – Evening, Cortisol – Noon.
ANY 2 HORMONES: Estriol (E3), DHEA, Melatonin – PM, Cortisol – Evening, Cortisol - PM (Night)
SINGLE HORMONE
17
Key Points for DDI Serum Test:• Assesses both IgG tTG and IgA tTG
separately and assesses all iso-forms (other labs don’t test all iso-forms; just number 2).
• Assesses DGP for both IgG and IgA for covering those individuals that are IgA deficient (a fair number of people nowadays) and children.
• Assesses both Anti Gliadin IgG and IgA; assesses all sub-fractions (other labs don’t test all sub-fractions; just α-gliadin).
• Assesses IgE Wheat Antibodies.
• Assesses Total Serum IgA.
• Provides insight into Coeliac and NON-Coeliac Gluten Sensitivity.
Celiac & Gluten Sensitivity Panel – SerumDoctor’s Data, Inc (DDI) a premier clinical laboratory with over 30 years experience, provides speciality testing to healthcare practitioners around the world. DDI’s Gluten Sensitivity Panel is the best determination of Coeliac we can achieve in the blood but it’s not limited to only Coeliac, it checks for the ‘other possibilities’ – Non-Coeliac gluten sensitivities.
TESTINGSNAPSHOTAssessing CoeliAC DiseAse and non-Coeliac gluten sensitivity
Functinal & Integrative Medicine Ltd, 77 Austin St, PO B 19033, Onekawa, Napier 4146 NZPh 0800 439 633 | Fax 0800 439 630 | [email protected] | www.fxmed.co.nz
What Makes gluten so Problematic As A source of Food-Based Reactivity?
Due to it being, by nature, highly resistant to digestion, gluten has been associated with numerous digestive and inflammatory complaints. However the degree that this is so, appears to stem well beyond the merely structural.
Due to possessing some relatively unique and formidable characteristics of its own, and being invariably accompanied by numerous other potentially disruptive and anti-nutrient compounds, gluten and the grains that contain it, appear to have an entire swathe of physical and metabolic consequences, all of which appear to be almost universally inflammatory.
DDi’s gluten sensitivity Panel is the best determination of Coeliac we can achieve in the blood but it’s not limited to only Coeliac, it checks for the ‘other possibilities’ – non-Coeliac gluten sensitivities.
tTg has been used since the mid-90’s-2000’s as the best marker to use for Coeliac in the blood. DgP came about more recently and is a valuable addition to gluten reactivity screening and picks up the subset of the population that tTg may not be as reliable for (i.e. children and igA deficient individuals).
tTg (Tissue Transglutaminase) is an enzyme that facilitates cross-linkage of extracellular matrix proteins in the tissue in an effort to repair injured and inflamed tissue. gluten can trigger an abnormal response whereby the body perceives it as foreign antigens and thus antibodies to tTg are produced causing the repair function of Transglutaminase to noT do its job. These auto-antibodies (anti- tTg) can be detected through serum blood draw providing ‘gold standard’ assessment in screening Coeliac Disease (CD). Despite being a categorical marker of CD, there is a small subset of individuals that you may see variability in using tTg alone (children & igA deficient individuals), therefore, Deamidated gliadin Peptides (DgP) are assessed to pick up the short-fall of tTg in those individuals. This allows the serum option to be the most comprehensive assessment available (short of doing a histological analysis of the small intestinal mucosa) which offers detection and differentiation of Coeliac Disease, non-Coeliac gluten sensitivity, Wheat Allergy and igA insufficiency in a diverse range of populations.
The nature of gluten
gluten is a collective term for the series of hardy proteins that give strength and integrity to many grass seeds (cereal grains). The term ‘gluten’ is almost exclusively used to refer to that of Wheat, Rye, Barley and often oats, and therefore so will the following.
Wheat gluten is made of numerous protein sub-fractions. These are predominantly divided into gliadins and glutenins (which occur in about even proportions within most forms of gluten).
The viscoelasticity that gluten affords to many culinary traditions is attributable primarily to the concatenating structures formed by the interaction of high and low molecular weight glutenins that constitute the insoluble components of gluten.
The gliadins on the other hand constitute the more soluble components and can be divided into further sub-fractions within the categories of α-gliadin, β-gliadin, γ-gliadin, and ω-gliadin.
Functinal & Integrative Medicine Ltd, 77 Austin St, PO B 19033, Onekawa, Napier 4146 NZPh 0800 439 633 | Fax 0800 439 630 | [email protected] | www.fxmed.co.nz
serum vs. Blood spot for Doctors Data gluten sensitivity Panels
Serum DrAW(Total IgA, Wheat IgE, tTG (IgA, IgG), DGP (IgA, IgG), Gliadin (IgA, IgG)
BLOOD SPOT(Gluten (IgG), DGP (IgA, IgG), Gliadin (IgA, IgG)
• Gold Standard assessment for Coeliac detectionbecause it includes multiple markers to catch anyvariances in population (specifically children, igAdeficient individuals).
• Also differentiates between Coeliac Disease, non-Coeliac gluten sensitivity, Wheat Allergy and igAinsufficiency.
• some level of gluten exposure is still required,however, DgP can still be detected in 80% of glutenresponders.
Markers tested:
• Tissue Transglutaminase (tTg) Antibodies igA(includes all iso-forms – 2, 3 and 6)
• Tissue Transglutaminase (tTg) Antibodies igg(includes all iso-forms – 2, 3 and 6)
• Deamidated Peptide (DgP) Antibodies igA
• Deamidated Peptide (DgP) Antibodies igg
• gliadin Antibodies (igA)(includes all sub-fractions – α, β, γ and ω)
• -gliadin Antibodies (igg)(includes all sub-fractions – α, β, γ and ω)
• ige Wheat Antibodies
• Total serum igA
• offers DgP markers for Coeliac detection (particularlyin children and igA deficient individuals)
• offers indications of non-Coeliac gluten sensitivity.
• some level of gluten exposure is still required,however, DgP can still be detected in 80% of glutenresponders.
• needs to be combined with the tTg for comprehensiveCoeliac assessment. *Us Biotek – Coeliac AntibodyPanel Blood spot (tTg (igA), gliadin (igA, igg)).
Markers tested:
• Deamidated Peptide (DgP) Antibodies igA
• Deamidated Peptide (DgP) Antibodies igg
• gliadin Antibodies (igA)(includes all sub-fractions – α, β, γ and ω)
• gliadin Antibodies (igg)(includes all sub-fractions – α, β, γ and ω)
• gluten Antibodies (igg)
Which is better out of tTg and DgP?
There are cases where individuals may respond better in one or the other thus combining the two (which is offered through DDI serum test) is showing the whole story.
Key Points for DDi serum Test:• Assesses both igg tTg and igA tTg separately and assesses all iso-forms
(other labs don’t test all iso-forms; just number 2).
• Assesses DgP for both igg and igA for covering those individuals that are igA deficient (a fair number of people nowadays) and children.
• Assesses both Anti gliadin igg and igA; assesses all sub-fractions (other labs don’t test all sub-fractions; just α-gliadin).
• Assesses ige Wheat Antibodies.
• Assesses Total serum igA.
• good thing about this test is that it provides insight into Coeliac and non-Coeliac gluten sensitivity.
20% off
Offer expires 26/11/19
Available from Functional & Integrative Medicine Ltd, 77 Austin St, PO Box 19033, Onekawa, Napier 4146, NZPh: 0800 439 633 • Fax: 0800 439 630 • [email protected] • www.fxmed.co.nzAvailable from Functional & Integrative Medicine Ltd, 77 Austin St, PO Box 19033, Onekawa, Napier 4146, NZPh: 0800 439 633 • Fax: 0800 439 630 • [email protected] • www.fxmed.co.nz
Gluten Sensitivity Panel - Serum
LAB #: B141106-0349-1PATIENT: Kallum RobinsonID: P143100204SEX: MaleDOB: 07/19/1999 AGE: 15
CLIENT #: 31417DOCTOR: Research Nutrition Pty Ltd18 / 93 Rivergate PlMurarrie, Qld, 4172 AUSTRALIA
ANTIBODIESREFERENCE
RESULT/UNIT INTERVAL NEG WEAK POS POSITIVE
Tissue Transglutaminase (tTG) IgA 42.2 U < 20.0
Tissue Transglutaminase (tTG) IgG < 3.8 U < 20.0
Deamidated Gliadin Peptide (DGP) IgA < 5.2 U < 20.0
Deamidated Gliadin Peptide (DGP) IgG 3.0 U < 20.0
Gliadin IgA 12.0 U < 20.0
Gliadin IgG 8.0 U < 20.0
Wheat IgE 0.04 kU/L < 0.08
PERCENTILE
2.5th 16th 50th 84th 97.5th
Immunoglobulin A (IgA) 1.12 g/L 0.66- 4.33
Celiac Disease/Gluten Sensitivity/Wheat Allergy Cascade
SPECIMEN DATA
Comments:
Date Collected: 11/03/2014Date Received: 11/06/2014 <dl: less than detection limit
Date Completed: 11/10/2014Method: Chemiluminesent, Immunoassay
©DOCTOR’S DATA, INC. ADDRESS: 3755 Illinois Avenue, St. Charles, IL 60174-2420 CLIA ID NO: 14D0646470 MEDICARE PROVIDER NO: 1484530001905
SAMPLE000000000
NOT sensitivity or allergy in this case
Classic indication
of Celiac that
is valid because
IgA sufficiency has been confirmed
Sample report
Serum vs Blood Spot comparison table
FxMed offers serum and blood spot tests. Serum is the gold standard. Please note that the serum test (only) is on special at 20% off.
18
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