korea bioindustry

Status of Korea BIO Industry

15Th April 2016

Jaehyuck Jerry Yang Head of Business Development

Korea Biotechnology Industry Organization

Korea Bio Industry 2

Status of Korea BIO Industry


Status of Korean Biotech Value Chain

Source technology

Science

Technology

Product

Univ, Institute

BIO-venture

Pharmaceutical company

Patents Regulation

- Korea, Science sector 12th, Patent sector 4th

-1st generation of Korean Biotech company have more than 15 years

- Entrance of conglomerate company and pharmaceutical company

- Supported by IT Infra and clinical capacity

Benefit

“Clinician”

ICT

Development

conglomerate

Source: KB Investment


Technology gap


Bio-Clusters supporting R&D Growth

Source: Invest Korea – Medical/Bio Promising Investment Opportunities (2012), Quintiles Internal Analysis.

Synergistic relationship between Bio-Clusters, Regional Clinical Trial Centers (Hospitals) & Pre-Clinical Facilities


Clinical Trials Country Ranking



Clinical Trials City Ranking



Clinical Trials in Korea



Venture Capital Investment

ETC

Distribution/Service

Game

Movie/Music/Event

BIO/Medical

Chemical/Metrials

Elect/Machine/Device

ICT Service

ICT Manufacturing

• 2015 Bio/Medical Investment : 284 M US$

• 2015 Bio/Medical Investment Ratio : 15.2%

• Early 2000 Bio/Medical Investment Ratio : 2%


Korea Drug Development Fund (KDDF)


Recent Highlights in Korea

Giant Going into Medical device

Samsung investment 2 billion in medical device (acquired Medison) SK investment in Nanoentech

Biological drugs

2 billion investment in biosimilar (Samsung Biologics with Qunitiles) Celltrion getting 200 million investment from Temasek LG investing in biosimilars

Regenerative medicine

Smart Healthcare

Stem-cell research, later state clinical development

Feasibility study undergoing with 10,000 diabetic patients


Bio-tech Company Activities

Global pharmaceuticals

Bio-tech company

Laboratory

Unmet needs

License out or

M&A

Source: KDB Daewoo Security

Value Chain Type Korean Golobal

M&A SD Inverness Medical

Innovations(USA)

Cooperation

Binex Nichi-Iko Pharmaceutical

(Japan)

Joint Venture

Donga Pharm. Meiji Seika Pharma (Japan)

Genexine Ajinomoto (Japan)

Yuhan Corp. Sorrento Therapeutics

(USA)

Tech. Transfer

Meditox Allergan(USA)


Joint Venture

Yuhan(51%) + Sorrento(49%)

Immune checkpoint Monoclonal Antibodies

Northlad(51%)+Huons(45%)+Interlim(4%)

eye bath drops


Joint Venture

Ajinomoto Genexine Co., Ltd.

Ajimoto(75%) + Genexine(25%) Medium Business

인천 송도 공장 준공(2014) Biosimilar(Korea, Japan Market)


Technology Transfer

• Hanmi Pharm-Sanofi(Diabetes)

• Hanmi Pharm-BI (EGFR)

• Hanmi Pharm-Zai Lab (EGFR)

• CJ-Luoxine Biotech (PCAB in GERD)

• Kainosmedicine-YANGZHOU AIDEA BIOTECH(2Anti-cancer drug)

• Legochembio-Fosun Pharma (ADC antibody)

• Sorrento-Lee's Pharma (PD-L1 antibody)

• Genexine-Talsy (3 protein therapies)


About KoreaBIO


KoreaBIO - History

1982. Korea Biotechnology Research Association(KBRA) founded

1991.11 Bio-industry Association of Korea(BAK) founded

2000. 7 Korea Bio-venture Association(KOBIOVEN) founded

2008.11 BAK, KOBIOVEN and KBRA merged into Korea BIO


• Pangyo Techno Valley – Korean Silicon Valley

• Korea Bio Park consist of 3 buildings with 22 Companies.

• Communication and Sustainability

+30 companies +1,000 People + 2 Association

KoreaBIO - Korea Bio Park(since 2005)


KoreaBIO - Member Company

Most of the top pharmaceutical

companies

Most of 35 bio-technology

companies listed on the Kosdaq

They have worked in

Bio-technology,

Pharmaceutical,

Medical device etc

Total + 300 member companies

<Top 10 Pharm Companies in Korea>

Rank Company Name Sales(M$)

1 Hanmi Pharm 11.46

2 Yuhan Corporation 9.81

3 Green Cross 9.11

4 Kwangdong 8.31

5 Daewoong Pharma 7.30

6 Celltrion 5.25

7 Jeil Pharm 5.17

8 Chong Kun Dang 5.15

9 Donga ST 5.05

10 Ildong Pharma 4.14


Korea Bio Activity

R&D

Education

Business

/Investment

Policy

/Regulation

Member

Service

+300 Members +28 Staffs


Cooperation with China

• 2013.6 MOU with BPBC(Beijing Pharma and Biotech Center)

• 2015.4 MOU with Zhongguancun Changping Science Park

• 2015.9 Korea-China Bio Forum & Partnering

• 2013.10-2015.10 Health Industry Forum in Beijing(3times)

• 2016.5 Korea-China Bio Forum & Partnering


Innovation Initiatives

Cure Diagnosis Care & Prevention

Molecular Diagnosis Medical Devices

Pharmaceuticals Company DNA sequencing

Medical service effectiveness improvement opportunity cost reduction

Healthcae Service Trends

KoreaBIO’s Innovative cooperation with new Committees

Korea IVD Committee

•Since 2011

•75 companies

Korean Genome Company

Committee

•Since 2015

•16 companies

Smart Healthcare

Committee

•Since 2015

•Kick off meeting on Oct 13th


Jaehyuck Jerry Yang KoreaBIO [email protected] +82-31-628-0021

mailto:[email protected]