current status of bioindustry in korea
TRANSCRIPT
Current Status of Biotech Industry
in Korea : Strengths and Challenges
December 2005
Jin-Ho Seo, Ph.D.Director, Bio-MAX Institute, Seoul National University
Bioindustry Association of Korea(BAK)
EU-Korea Biotech Seminar
Ⅰ. Fundamental Structure of Bioindustry in Korea 1. History of Korean Bioindustry 2. Bioindustry Fields 3. Government Role and R&D Investment 4. Journal & Patent 5. Driving System
Ⅱ. New Breakthroughs of Bioindustry in Korea 1. Vision for BioSociety and Goal of Bioindustry 2. Basic Direction of Bioindustry Policy 3. Strengthening Strategy of Competitiveness on Bioindustry 4. What We Focus On
Ⅲ. Current Status of Bioindustry in Korea 1. Category of Companies 2. Manpower of Companies 3. Market Size 4. Example of Bio-Products 5. Trend of Technology Development 6. Investment by Major Corporates 7. Industrialization by Major Corporates 8. Launching Trend of New Bio-products 9. SWOT of the Korean Bioindustry 10. Strengths and Challenges
Ⅳ. Future of Korean Bioindustry 1. Prospect for the Future 2. Strategy for the Future
CONTENTS
1. History of Korean Bioindustry
1980~1989 : Technology Development Stage Introduction & Development of New Biotechnology
Enactment of Biotechnology Promotion Law, 1983
Establishment of Biotechnology Departments & Research Institutes in Universities, 1984
Establishment of the Korea Research Institute of Bioscience & Biotechnology(KRIBB), 1985
1990~1999 : Product Manufacturing Stage Establishment of Bioindustry Association of Korea(BAK), 1991
Formalizing of Biotech 2000 Program(MOST), 1994
Proclaim of Bioindustry Vision 2000(MOCIE), 1994
Development of Bioprocess Technology & Launching of Bio-products
2000~Current : Bioindustry Introduction Stage Establishment of Korean Bioindustry Development Strategy, 2000 Key National Strategic Industry Inauguration of National Bioindustry Action Plan
Productivity Improvement of Generic Products, Development of New & Modified Bio-products
Investment Increase in Public & Private Sector
1I. Fundamental Structure of Bioindustry in Korea
Areas Contents
BiochemicalsBiopolymer, Industrial enzymes, Organic acids, Amino acids, Reagents & Kits, Bioagrochemicals, etc.
BioenvironmentsWaste water & Wastes treatment, Bioremediation, Polution monitoring, Microbial agents, etc.
BiopharmaceuticalsImmunomodulator, Growth factor, Blood protein, Antibiotics, Vaccines, Diagnostics, Tissue & Cell engineering, Gene therapy, etc.
Bioenergy & Resources
Biomass & Biogas, Artificial seed & tree, Transgenic animal & plant, Marine bioresources, etc.
BiofoodsAmino acid, Functional peptide & protein, Functional lipid & carbohydrate, Food additives & enzymes, etc.
BioelectronicsDNA chip, Protein chip, Lab on a Chip, Biosensors, Bio MEMS, Bio devices, etc.
Bioprocess & Bioequipment
Fermentation, Cell culture, Bioconversion, Separation & Purification, Formulation, Bioengineering, etc.
Bioevaluation & Bioinformatics
Safety evaluation, Efficacy evaluation, Biostandardization, Bioinformatics, etc.
Bioindustry Fields
Source : Korea Institute for Industrial Economics & Trade(KIET), 2004
2. Bioindustry Fields
2I. Fundamental Structure of Bioindustry in Korea
Department Main Role
Ministry of Commerce, Industry and Energy
(MOCIE)
Applied Biotechnologies and Industrialization
Development of Substitute Energy
Ministry of Science and Technology
(MOST)
Basic and Leading-edge Technologies
Promotion of Biotechnology-supporting Systems
Ministry of Education & Human Resources
Development(MOE)
Education
Assistance of Basic Researches on Life Science
Ministry of Health and Welfare
(MOHW)
Development of New Biopharmaceuticals
Clinical Trials & Regulations
Ministry of Agriculture & Forestry
(MAF)
Breeding Animals, Plants
New Food Additives
Ministry of Environment
(ME)
Preservation and Use of Biodiversity
Development of Wastes Treatment Technology
Ministry of Maritime & Fisheries
(MOMAF)
Conservation of Marine Resources
Gene Analysis of the Marine Species
Government Role in Bioindustry
Government Role
I. Fundamental Structure of Bioindustry in Korea 3
3. Government Role and R&D Investment
Source : Biotechnology Promotion Law
Research InstitutesResearch Institutes
Governmental AgenciesGovernmental Agencies
US$ 450 million R&D Investment by 7 Ministries in 2003
US$ 525 million R&D Investment by 8 Ministries in 2004
Governmental AgenciesGovernmental Agencies
US$ 450 million R&D Investment by 7 Ministries in 2003
US$ 525 million R&D Investment by 8 Ministries in 2004
Industries Industries
Bioindustry Association of Korea
Korea Biotechnology Research Association
Korea Bio Venture Association
Biotech Institutes in Private Companies
Bioindustry Association of Korea
Korea Biotechnology Research Association
Korea Bio Venture Association
Biotech Institutes in Private Companies
AcademiaAcademia
Biotechnology-related Departments in Universities
University-associated Research Institutes
Science & Engineering Research Centers
Biotechnology-related Societies
Biotechnology-related Departments in Universities
University-associated Research Institutes
Science & Engineering Research Centers
Biotechnology-related Societies
Korea Research Institute of Bioscience and Biotechnology
POSTECH Biotech Center
Biocluster : Bio Venture Center & New Region Promotion Business
Other Governmental or Public Research Institutes
Korea Research Institute of Bioscience and Biotechnology
POSTECH Biotech Center
Biocluster : Bio Venture Center & New Region Promotion Business
Other Governmental or Public Research Institutes
Government R&D Investment
I. Fundamental Structure of Bioindustry in Korea 4
3. Government Role and R&D Investment
Case published in the Journals listed by SCI
I. Fundamental Structure of Bioindustry in Korea 5
4. Journal & Patent
43 55 69120
246300 308
394445
498
050
100150200250300350400450500
SC
I(C
ase
)
1991 1992 1993 1994 1995 1996 1997 1998 1999 2000
Year
Source : Ministry of Science and Technology(MOST), Biotechnology in Korea
Patent registration to the US PTO
I. Fundamental Structure of Bioindustry in Korea 6
4. Journal & Patent
3
710
6
15
23
13
26
0
5
10
15
20
25
30
Pa
ten
t
1994 1995 1996 1997 1998 1999 2000 2001
Year
Source : Ministry of Science and Technology(MOST), Biotechnology in Korea
5. Driving System Government
7I. Fundamental Structure of Bioindustry in Korea
Korean Intellectual Property Office(KIPO)
Genetic Engineering Examination Division
Korea Food & Drug Administration(KFDA)
Safety Evaluation Office
Ministry of Commerce, Industry and Energy(MOCIE)
Biotechnology & Chemicals Industries Division
Ministry of Science and Technology(MOST)
Biotech and Environmental Technology Division
Ministry of Education & Human Resources Development(MOE)
Ministry of Agriculture & Forestry(MAF)
Ministry of Health and Welfare(MOHW)
Ministry of Environment(ME)
Ministry of Maritime Affairs & Fisheries(MOMAF)
Academia
I. Fundamental Structure of Bioindustry in Korea
5. Driving System
Biotechnology-related Departments were set up in around 40 Universities
College of Science 60%, College of Agriculture 25%, College of Engineering 15%
30 University-associated Research Institutes on the Genetic Engineering were established
Institute of Molecular Biology and Genetics, Seoul National University, etc.
Science Research Center(SRC) & Engineering Research Center(ERC)
Over 20 Centers in Biotechnology Area in the Universities
Seoul National University, Korea University, KAIST, etc.
Biotechnology-related Societies are Working on
Korean Society for Biotechnology and Bioengineering(KSBB)
Korean Institute of Chemical Engineering / Division of Biochemical Engineering, etc.
8
Research Institutes Biotechnology-dedicated Research Institutes
Korea Research Institute of Bioscience and Biotechnology(KRIBB) is the only government research
institute dedicated to biotechnology research across a broad span of expertise, from basic studies
for the fundamental understanding of life phenomena to applied studies, established in 1985
Korea Research Institute of Bioscience and Biotechnology(KRIBB)
MOGAM Biotechnology Institute is one of the best private research institutes established in 1984
on the promotions of the research and development in the field of Biopharmaceuticals
MOGAM Biotechnology Institute
I. Fundamental Structure of Bioindustry in Korea
5. Driving System
9
SNU Bio-MAX Institute is a research organization established in 2003 with a support from MOCIE
to carry out innovative projects in a multidisciplinary environment
Bio-MAX Institute, Seoul National University
Biocluster
Biotechnology Innovation Center, Chuncheon Bio Venture Center, Daejeon Center for Biotechnology and Bioventure,
Jeonbuk Bio21 Center, Kyungnam Biotechnology Industrialization Center,
Dongshin University Biotechnology Innovation Center,
Youngdong University Technology Innovation Center,
Sangju National University Bioindustry Development Center, Jeju Marine Biotechnology Center for Functional
Material Industry, Busan
Bio Venture Town, Daejeon Bio Venture Plaza, Chuncheon Institute for Marine Bioindustry, Gangneung Biotechnology Center for Bioindustry, Jeonnam Biotechnology Research Center, Jeonnam Biohealth Industry Support Center, Kyungbuk Bioscience Park, Jeju Traditional Pharmaceutical R&D Center, Chungbuk
Animal Resources Support Center, Chungnam Healthcare Industry Center, Chungbuk Marinebio Enviromental Industry Center, Kyungbuk
Biomaterial Industrialization Center, Daegu Herb Medicine Support Center, Daegu Bio Venture Plaza, Kyungnam Bio-Industry Support Center, Busan
New Region Promotion Business(15)Bio Venture Center(9)
Research Institutes
I. Fundamental Structure of Bioindustry in Korea
5. Driving System
10
Biotechnology-related Research Institutes
Korea Institute of Science and Technology(KIST) Korea Tomorrow & Good Research Institute(KTGRI) Korea Food Research Institute(KFRI) Korea Institute of Toxicology(KIT) Korea Biotechnology Commercialization Center(KBCC) Korea Institute of Energy Research(KIER) Korea Ocean Research & Development Institute(KORDI)
Korean Agency for Technology and Standards(ATS) National Institute of Health(NIH) National Institute of Environmental Research(NIER) National Institute of Agricultural Science and Technology(NIAST) Korea Forest Research Institute(KFRI) National Veterinary Research and Quarantine Service(NVRQS) National Fisheries Research and Development Institute(NFRDI) National Institute of Scientific Investigation(NISI)
Government-donated Research Institutes
National and Public Research Institutes
Research Institutes
I. Fundamental Structure of Bioindustry in Korea
5. Driving System
11
Korean Collection for Type Cultures(KCTC)
Korean Culture Center of Microorganisms(KCCM)
Korean Cell Line Research Foundation
Microorganism Depository Organizations
Asan Institute for Life Science
Samsumg Bioscience Research Institute
Private Research Institutes
Korea Institute of Science and Technology Information(KISTI)
Agriculture and Life Science Research Center, Seoul National University
Biological Research Information Center(BRIC), Pohang University of Science and Technology
Research Institutes on Bioinformatics
I. Fundamental Structure of Bioindustry in Korea
5. Driving System
12
Others
Research Institutes
I. Fundamental Structure of Bioindustry in Korea
5. Driving Systems
13
Industry Organizations
Industrial Organization established as an affiliated Organization of Ministry of Commerce, Industry and Energy(MOCIE) in 1991 for the Purpose of the Development and Growth of Bioindustry in Korea
Main Activities
- Formation of Bioindustry Platform
- International Cooperation in Bioindustry
Members : General(Company : 60), Associate(Organization : 19, Individual : 110)
Research Association established as an affiliated Organization of Ministry of Science and Technology(MOST) in 1982 for the Purpose of the Support on the Development of Biotechnology
Bioventure Organization established as an affiliated one of Ministry of Commerce, Industry and Energy(MOCIE) in 2000
Bioindustry Association of Korea(BAK)
The Korea Biotechnology Research Association(KBRA)
Korea Bio Venture Association(KOBIOVEN)
Transformation to BioSociety where the Bio-Products and Services are
just on Your Hands
The Coming BioSociety after the Bio-Revolution of 21C through the Fusion of
Biotechnology(BT) and Information Technology(IT)
1. Vision for BioSociety and Goal of Bioindustry
14
Vision for BioSociety
The Core Contributor in Korea Economy in 21C
The paradigm shift in economy from mass assembly industry to knowledge based industry
Impact of Bioindustry
II. New Breakthrough of Bioindustry in Korea
Remaking the World Transforming Ourselves From Alchemy to Algeny
II. New Breakthrough of Bioindustry in Korea
1. Vision for BioSociety and Goal of Bioindustry
15
Settlement as Growth Engine Industry for Next generation
- Industrialization as the main force in Post-IT era
Commercialization of Export-driven Bio-Product
- Marketing of New Bio-Product in advanced countries
- Globalization of Korean traditional Bio-Products
Vision for Bioindustry
Export : US$ 0.7 billion(2002) US$ 10 billion(2012)
Targeting 10% of share in Global Market
Bioindustry Development Strategy 2005
Intensive Promotion of Bioindustry as a National Strategic Industry Active Lead toward Development of Bioindustry
2. Basic Direction of Bioindustry Policy
16
Creation of BioSociety for the 21st Century
Healthy BioSociety
Wealthy BioSociety
Clean BioSociety
II. New Breakthrough of Bioindustry in Korea
Growth of Bioindustry
3 Goals : R&D, Infra, Business Environment
12 Programmes : Bio-Star Project, Biocluster, etc.
3. Strengthening Strategy of Competitiveness on Bioindustry
17II. New Breakthrough of Bioindustry in Korea
Development of Core Technology - Technology for Mid-term & Next generation
Growth Engine Industry for Next generation - New Bio-Drug / Artificial Organ, Bio-Chip
Bio-Star Project - Innovative Biotechnology & Bio-Product
Establishment of Bio-product Manufacturing - International authorization of GLP System - Establishment of GCP system for Functional Active Compound - Expansion of cGMP and Improvement of Management
Implementation of LMOs - Biosafety Information Center - Foundation of Bio-hazard Evaluation Center
Expansion of Industrialization
Infrastructure
Development of Core Technology
& Bio-Product
3. Strengthening Strategy of Competitiveness on Bioindustry
18II. New Breakthrough of Bioindustry in Korea
Activation of Biocluster - Construction of Korea Bio-Hub - Strengthening of existing Biocluster - Promotion of using Micro-biochip production platform - Establishment of platform for supporting Industrialization of BIT technology
Establishment of Investment / Consulting Company - Participation from public company, private & foreign companies - Support of long-term investment
Construction of Complex - Advanced Biopharmaceutical production complex - Bulk Vaccine production complex
Joint R&D with Foreign Countries Training International Standard Specialist
Networking among Domestic & Foreign association, companies and government
Strengthening & Promoting of Biocluster
Promoting Global Network
4. What We Focus On
19II. New Breakthrough of Bioindustry in Korea
Development of Therapeutic Protein by Animal Cell Culture
Development of Biomaterial by Intelligence-type Bioinformatics
Development of Gene Therapy for Incurable Diseases
Mass Production of Protein-DNA chip System
Development of High Value Added Protein
Immunomodulator
Drug Delivery System
Gene Therapy
Cell Therapy
cGMP Technology
Growth Engine Project : New Bio-Drug / Artificial Organ & Bio-Chip
Mid-term & Next Generation Project
Types of Companies No. of Companies in 2003 : 605 No. of Companies on both R&D and Sales of Bio-Products : 432 No. of Companies focusing on R&D : 173
Types of Companies No. of Companies
Companies focusing on R&D 173
Companies working on R&D and Sales of Bio-Products
- Domestic Products
- Imported Products
432
(387)
(45)
Types of Bioindustry Companies in 2003
2004 No. of Companies in Bioindustry : About 600
1. Category of Companies
III. Current Status of Bioindustry in Korea 20
Source : Korean Agency for Technology & Standards, Korea Institute for Industrial Economics & Trade, Bioindustry Association of Korea, 2004
Company Group
Large
Size
Group
Large
Size
Group
Above 30 Companies
LGLS, CJ, Daesang, TS Corporation, etc.
Operating the fully Integrated System on R&D, Production, Marketing
Above 30 Companies
LGLS, CJ, Daesang, TS Corporation, etc.
Operating the fully Integrated System on R&D, Production, Marketing
Middle
Size
Group
Middle
Size
Group
Above 70 Companies
Dong-A Pharm., Chong Kun Dang, Green Cross, Daewoong, etc.
Focused on the Competitive Core Products
Above 70 Companies
Dong-A Pharm., Chong Kun Dang, Green Cross, Daewoong, etc.
Focused on the Competitive Core Products
SmallSize &
Venture Group
SmallSize &
Venture Group
Above 500 Companies
Dong Kook Pharm., Bioneer, Macrogen, KoBioTech, etc.
Individually concentrated on the Niche Fields of R&D, Production and Marketing
Above 500 Companies
Dong Kook Pharm., Bioneer, Macrogen, KoBioTech, etc.
Individually concentrated on the Niche Fields of R&D, Production and Marketing
III. Current Status of Bioindustry in Korea
1. Category of Companies
21
III. Current Status of Bioindustry in Korea 22
2. Manpower of Companies 2003 Total : 11,013
R&D Area : 5,808(53%)
Manufacturing Area : 5,205(47%)
2004 : About 13,000
Manpower of Bioindustry in 2003
Ph.D. M.S. B.S. Technician Total
R&D 1,001 2,654 1,593 560 5,808
Manufacturing 35 363 1,405 3,402 5,205
Total 1,036 3,017 2,998 3,962 11,013
Source : Korean Agency for Technology & Standards, Korea Institute for Industrial Economics & Trade, Bioindustry Association of Korea, 2004
3. Market Size 2003 : US$ 1,332 million Biopharmaceuticals 61%, Non-biopharmaceuticals 39%
Domestic Products 68%, Imported Products 32%
2004 : About US$ 1,701 million
Area Domestic Products Imported Products
Biopharmaceuticals
Biofoods
Biochemicals
Bioenvironments
Bioenergy & Resources
Bioprocess & Bioequipment
Bioelectronics & Bioinformatics
545
148
65
76
11
26
33
267
1
35
-
2
122
1
Total 904 428
1,332
Bioindustry Market Size in 2003(Unit : US$ million)
III. Current Status of Bioindustry in Korea 23
Source : Korean Agency for Technology & Standards, Korea Institute for Industrial Economics & Trade, Bioindustry Association of Korea, 2004
Human Growth Hormone
Vaccines : Hepatitis B Vaccine, etc.
α-Interferon, γ-Interferon
Antibiotics : 7-ACA, etc.
Diagnostic Kits
Amino Acids : Lysine, etc.
Oligosaccharides
Microbial Agents
Insulin
Human Growth Hormone
α-Interferon, β-Interferon
Vaccines : Influenza, etc.
Erythropoietin
Diagnostic Kits
Equipments : Bioprocess, etc.
Industrial Enzymes
Examples of Domestic Products Examples of Imported Products
III. Current Status of Bioindustry in Korea
4. Example of Bio-products
24
Upstream Technology : Well Developed
Recombinant DNA Technology, Cell Fusion Technology, etc.
Downstream Technology
Fermentation : Well Developed
Animal & Plant Cell Culture, Separation & Purification, etc. : Improving
Emerging Technology : Early Stage
Genomics, Proteomics, Bioinformatics, etc.
Use of Established Biotechnology
Improvement of level on Bioprocess Technology
Development of Post genomics-related New Technology
Industrialization of Improved and New Bio-products
Improved Bio-product
New Bio-product
Technology
Level
Trend of Technology Development
5. Trend of Technology Development
III. Current Status of Bioindustry in Korea 25
Investment to Biotech Investment to Biotech CompanyCompany
SamsungSamsung
SKSK
LGLSLGLS
DaesangDaesang
Green CrossGreen Cross
ISU ChemicalISU Chemical
DooSan DooSan
CJCJ
US$ 155 million by 2004US$ 155 million by 2004
US$ 230 million by 2003US$ 230 million by 2003
US$ 100 million by 2005US$ 100 million by 2005
US$ 115 million by 2006US$ 115 million by 2006
US$ 77 million by 2004US$ 77 million by 2004
US$ 32 million in 2001, domestic and oversea investment US$ 32 million in 2001, domestic and oversea investment
US$ 85 million to Biotech, 30 million to Biotech VenturesUS$ 85 million to Biotech, 30 million to Biotech Ventures
US$ 230 million by 2004US$ 230 million by 2004
6. Investment by Major Corporates Investment by Major Corporates
III. Current Status of Bioindustry in Korea 26
7. Industrialization by Major Corporates Industrialization by Major Corporates
III. Current Status of Bioindustry in Korea
Bio-Products of LG Life Science Ltd.
No.No. ProductProduct ApplicationApplication Approval Approval DateDate
1Intermax gamma
InjectionChronic myelogeneous leukemia(CML), Rheumatoid arthritis(RA) 1989
2Euvax B Injectio
nImmunization against infection caused by all known subtypes of hepatitis B virus 1992
3Intermax alpha I
njectionMultiple myeloma , Renal cell carcinoma, Malignant melanoma, Kaposi's sarcoma in patients with AIDS, Hairy cell leukemia, Improvement of viremia in chronic hepatitis B, etc.
1992
4Eutropin Injectio
nShort stature due to GHD, Short stature due to Turner's syndrome 1993
5 BoostinSustained-release(SR) formulation of recombinant Bovine Somatotropin(rBST) for increasing milk production in lactating dairy cows.
1994
6Leucogen Injecti
onNeutropenia due to chemotheraphy in patients with solid tumor, Neutropenia after bone marrow transplantation(BMT)
1995
7 HCD ELISA kit for the detection of Ab against hepatitis C virus 1995
8Hyal 2000 Injecti
onHyal 2000 Inj. is used during surgical procedures on the eyes, for example, cataract (intraocular lens implantation), keratotransplantation, glaucoma, etc.
1997
9Hyruan™ Injecti
onDeformative osteoarthritis of the knees, Shoulder periarthritis 1998
10Espogen Injectio
nAnemia in patients with chronic renal failure 1999
11LG Malaria
anti-P.V.ELISA kit for the detection of Ab against Plasmodium vivax 2000
27
7. Industrialization by Major Corporates Industrialization by Major Corporates
III. Current Status of Bioindustry in Korea
Sales of LG Life Science Ltd. from Main Bio-Products in 2003
28
Euvax BInjection
Immunization against infection diseases caused by subtypes of hepatitis B virus
$ 29 mil.
Eutropin Injection
Short stature due to GHD or due to Tuner’s syndrome
BoostinSustained-release(SR) formulation of recombinant Bovine Somatotropin(rBST) for inducing increased milk production in dairy cows.
Hyruan™ Injection
Deformative osteoarthritis of the knees or shoulder periarthritis
Espogen Injection
Anemia in patients with chronic renal failure
$ 19 mil.
$ 8 mil.
$ 6 mil.
$ 8 mil.
Sales
7. Industrialization by Major Corporates Industrialization by Major Corporates
III. Current Status of Bioindustry in Korea
Bio-Products of CJ Corp.
No. Product Application
1 7-ACA Intermediate for cephalosporins
2 Hepaccine-B Hepatitis B vaccine
3 VancomycinTreatment for the infection due to staphylococci and skin structure infections, etc.
4 Epokine Treatment of anemia associated with chronic renal failure
5 AlphaferonTreatment of multiple myeloma, malignant melanoma, Kaposi's sarcoma, hairy cell leukemia, and chronic hepatitis B viremia
6 Serratiopeptidase A proteolytic enzyme derived from Serratia spp
7 G-CSF Therapeutics of Neutropenia
8 Lysine Feed Additives
9 Nucleic Acid Food Additives
29
7. Industrialization by Major Corporates Industrialization by Major Corporates
III. Current Status of Bioindustry in Korea 30
Sales of CJ Corporation from Main Bio-Products in 2003
Lysine Feed additives $ 256 mil.
Nucleic Acid Food additives
7-ACA Intermediate for cephalosporins.
VancomycinTreatment for the infection due to staphylococci and skin structure infections, etc.
EpokineTreatment of anemia associated with chronic renal failure
$ 128 mil.
$ 22 mil.
$ 8 mil.
$ 27 mil.
Sales
7. Industrialization by Major Corporates Industrialization by Major Corporates
III. Current Status of Bioindustry in Korea
Bio-Products of Dong-A Pharmaceutical Co., Ltd.
No. Product ApplicationApproval
Date
1 ADM Anti-cancer 1988
2 Vaxigrip Influenza vaccine 1989
3 Dong-A Prostin Injection Chronic Arterial Scleosis 1993
4 Leucostim Injection Human granulocyte-colony stimulating factor 1995
5Dong-A Interferon alpha-2
InjectionMultiple myeloma, Malignant melanoma, Kaposi's sarcoma, Hairy cell leukemia, etc.
1996
6 Growtropin Human growth hormone 1999
7 Eporon Injection Treatment of Anemia 1999
8Dong-A Syphilis, HCV, HBsA
g ELISA, AIDSDIAAnti-Treponema pallidum Diagnostic Kit, Diagnosis of Hepatitis C, B,
Diagnosis of HIV
31
7. Industrialization by Major Corporates Industrialization by Major Corporates
III. Current Status of Bioindustry in Korea
Sales of Dong-A Pharmaceutical Co., Ltd. from Main Bio-Products in 2003
32
Eporon Injection
Treatment of anemia $ 5 mil.
Vaxigrip Influenza vaccine
Leucostim Injection
Human granulocyte-colony stimulating factor
Beszyme Tab Treatment of Indigestion and dyspepsia
Growtropin Human growth hormone
$ 7 mil.
$ 9 mil.
$ 4 mil.
$ 4 mil.
Sales
8. Launching Trend of New Bio-Product Launching Trend of New Bio-Product
III. Current Status of Bioindustry in Korea 33
Cell & Tissue Therapy
SureDerm™(approved in 2000)
Acellular human dermis for the repairor replacement of damaged tissue.
Chondron(approved in 2001)
Autologous chondrocyte transplantation(ACT)
Holoderm(approved in 2002)
Cultured epidermal autograft(CEA)
Hans Biomed
Cellontech
Tego Science
Products ApplicationCompanies
8. Launching Trend of New Bio-Product Launching Trend of New Bio-Product
III. Current Status of Bioindustry in Korea 34
Bio-Chip
MyGene Inc. Detection of Human Papillomavirus(HPV)
High sensitivity and specificity for the detection
of cervical disease in early stage
Minimal specimen preparation required
Cost effective and user-friendly test
My HPV Chip(approved in 2004)
HPVDNAChip(approved in 2004)
Biomedlab Co. Detection of Human Papillomavirus(HPV) Accurate risk determination by genotype
information
Assist diagnosis or prognosis of cervical cancers
Useful in vaccine development and evaluation
9. SWOT of the Korean Bioindustry SWOT of the Korean Bioindustry
III. Current Status of Bioindustry in Korea 35
• International Level of IT Technology • Enthusiasm to Education• Strong Driving Policy of Government
• International Level of IT Technology • Enthusiasm to Education• Strong Driving Policy of Government
StrengthStrength
• Narrow gap in the Potential of Korea with Advanced Countries• Innumerable fields to be Investigated• Increase of the interests in Bioindustry among Koreans
• Narrow gap in the Potential of Korea with Advanced Countries• Innumerable fields to be Investigated• Increase of the interests in Bioindustry among Koreans
OpportunityOpportunity
• Inferior in Technology Competitiveness • Far behind level in Industrial Infrastructures• Insufficient Investment
• Inferior in Technology Competitiveness • Far behind level in Industrial Infrastructures• Insufficient Investment
WeaknessWeakness
• Spread of the Anxiety on Bio-Products• Monopoly of the Patents and IPR by a limited no. of Countries• Speedy of Technology Development
• Spread of the Anxiety on Bio-Products• Monopoly of the Patents and IPR by a limited no. of Countries• Speedy of Technology Development
ThreatThreat
10. Strengths and Challenges Strengths and Challenges
III. Current Status of Bioindustry in Korea 36
Stem Cell R&D
Embryo Originated Stem Cell
Cloned cow, dog
Development of mini pig
Challenges
Amino Acid & Food Additives
Amino Acid : Lysine, etc.
Food Additives : Nucleic Acid, etc.
Strengths
BIT
Biochip, etc.
Biopharmaceuticals
Antibiotics : 7-ACA, etc.
Gene Drug : Hepatitis B Vaccine, etc
37
Creation of BioSociety for the 21st Century
Healthy BioSociety
Wealthy BioSociety
Clean BioSociety
Ready for BioSociety Growth of Bioindustry
IV. Future of Korean Bioindustry
Intensive Promotion of Bioindustry as a National
Strategic Industry
Enhancement of International Cooperation
with China, etc.
Active Lead toward Development
& Enlargement of Bioindustry
1. Prospect for the Future Prospect for the Future
38IV. Future of Korean Bioindustry
Strong Support Policy by Government
Securing the Research Manpower by Education and Training
Support to Build-up of t Infrastructures for Research and
Commercialization
Increase of R&D Investment
Encouragement of Industry / Academia Cooperation
Formulation of Consortium System by Bio-companies
Encouragement of International Cooperation
Support to Venture Capitals + Industries
Support to Bioclusters
2. Strategy for the Future Strategy for the Future