kirk man beginners guide web[1]
TRANSCRIPT
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IMPORTANT
The material in this guide is for informational use only. It should
not be used as a substitute for advice from a health care professional.
Please consult with a health care professional regarding the application
of this material to your own personal needs and situation.
This publication is not intended to diagnose, treat, cure or prevent
any disease.
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INTRODUCTION 6What if I Don’t Have A Doctor Right Now? 6So Where Do I Begin? 7What Is a Poor Nutritional Profile? 7Products to Correct a Poor Nutritional Profile 8
How Long Should I Try These Products? 10 SPECIAL DIETS 11
The Gluten-Free/Casein-Free Diet Explained 11How Long Must I Use the GF/CF Diet? 11
Casein Restriction 12Gluten Restriction 13
Frequently Asked Questions about the GF/CF Diet 14The Specific Carbohydrate Diet (SCD) 15
THE IMPORTANCE OF GASTROINTESTINAL HEALTH 16Signs of Gastrointestinal Disturbances 16The Intestinal Immune System 17Gastrointestinal Tract: A Top Priority 18Digestive Function 18
Digestive Enzymes 19Digestive Irregularities 19
How Long Should the Trial Period be on Enzymes? 21Probiotics 21How Long Should the Trial Period be on Probiotics? 21
IMMUNE SUPPORT 22General Facts About Our Immune System 22Signs of Immune Deficiencies 23Sleep Issues 24
BIOCHEMICAL PATHWAYS 25Sulfation 25Methylation 25Oxidative Stress 26
BEHAVIORAL CONSIDERATIONS 27
TOXIC LOAD/HEAVY METALS 29
What Could be Signals of a Toxic Load Burden? 29Minimizing the Toxic Load 30Detox-Aid Advanced Formula 30How Does Detox-Aid Advanced Formula Work? 30Heavy Metal Detoxification 31
DON’T OVERLOOK THE HYPOALLERGENIC FACTOR 32Why Aren’t All Products Made to be Hypoallergenic 33What Have Been the Results of Individuals Using
Kirkman’s Hypoallergenic Line? 33 IDEAS ON HOW TO GET YOUR CHILDREN TO
TAKE NUTRITIONAL SUPPLEMENTS 35 APPENDIX A 36
Step-by-Step Recap of Interventions 36
The Top Three Interventions to Try 36Next Possible Steps 36The More Complicated Interventions 36
Laboratory Testing 37Kirkman’s Customer Service Staff and Technical
Staff Can Help 37NOTES 38
Kirkman Contact Information 39
TAble OfcONTeNTs
TAble Of cONTeNTs
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beGINNeR’s GUIDeTO bIOMeDIcAl
AND DIeTARy
INTeRVeNTIONs
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What If I Don’t Have a Doctor Right Now ?Kirkman always recommends that the interventions
described in this guide be carried out under the care
of a physician who specializes in the care of individuals
with sensitivities. Such doctors can be hard to locate
and once located can have a significant waiting period
for appointments. Add to this delay the time needed
to perform necessary laboratory tests, and it can be
an extremely long time before the physician begins a
treatment regimen for your child. In the meantime, you
may want to try certain supplements or special diets.These interventions are okay to try on your own as long
as you follow the instructions regarding the diet and on
supplement labels.
INTRODUCTION
Biomedical and dietary interventions in individuals can be very
challenging and complex. This guide is an attempt to simplify
the approach and provide an understanding and background for
biomedical interventions, along with a logical sequence for theindividual or parent and doctor to follow.
Many Kirkman customers attend conferences, read articles or
books, hear media programming or consult with their physician
only to come away overwhelmed, confused and unsure where
to begin. This guide should help map out a logical approach for
the parent and doctor to agree upon. It is formatted so as to
coincide with the information found on the “Kirkman Roadmap”
that is on the inside cover of this book or you can download or
order from Kirkman’s website at www.kirkmanlabs.com.
A simplified recap of the step-by-step interventions described
in detail in this guide is provided in Appendix A . This recap is
provided to help you prioritize the biomedical and dietary con-
siderations that may meet your special requirements.
You may want to try nutritionalsupplements to get started.
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So Where Do I Begin?
Generally speaking, most physicians recommend correcting poor nutri-
tion first, since most individuals with special dietary requirements exhibit
poor eating habits. Often this involves basic nutritional supplements as
well as a special diet, although one can be done without the other to
start. If you are already on a special diet, just start the supplementation,
while if you are not on either, you may start one or the other or both.
What Is a Poor Nutritional Profile?
A poor nutritional profile is a series of nutritional deficiencies that may
be present in an individual. It is very prevalent in individuals with dietary
sensitivities for numerous reasons.
Some of these reasons include:
• Specialdietssuchasthegluten-free/
casein-free(GF/CF) ortheSpecificCarbohydrateDiet
(SCD)maybeinplace,
which are not nutritionally balanced.
• Aperson’stastesandattitudescan
be such that an individual’s diet is
very deficient in vitamins, minerals,
or other nutritional necessities.
• Afacetofbiochemistrycanbe
irregular, making the
absorption of nutrients sub-optimal.
Poornutritioncanoftenbe(thoughnotalways)
recognized by:
• Visionissues
• Unhealthyskintone
• Extremetirednessorlackofenergy
• Behavioralissues
• Failuretothrive
• Frequentillness
Parents often detect some or most of these conditions prior to a physi-cian’s evaluation or laboratory testing.
Correctingapoornutritionalprofileiscrucialtogoodhealthinindi-
viduals with dietary sensitivities. For those on a casein free diet, calcium
Many children with sensitivities crave thefoods to which they are allergic.
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supplementation is essential to proper bone development and growth.
Furthermore, a comprehensive vitamin and mineral supplement is es-
sential when the diet is unbalanced and deficient, which is often the case
if all food categories including protein, fruits, vegetables and carbohy-
dratesarenotconsumed.Codliveroilandomega-3fattyacidsupple-
ments can help support good vision and healthy skin. Irregularities in bio-
chemicalpathwaysareoftensupportedbyB-6/magnesiumsupplements,
folic or folinic acid, or sulfation aids.
Certainnutrientsareessentialforpropersupportoftheimmunesys-
tem.Zinc,vitaminA,vitaminC,vitaminE,andseleniumareexamples
of nutrients that improve immune response. Sub-optimal levels of these
nutrients can sometimes lead to poor immune response.
A physician’s evaluation and laboratory testing will help confirm these
deficiencies and point you and the doctor in the right direction, but until
such time as that evaluation and testing takes place, these nutritional
options are safe and do not cause serious side effects as long as one does
not exceed safe levels that your nutritionist or physician recommends.
Sometimes a poor nutritional profile can be due to enzyme insufficien-
cy. If this is the case, even eating a well balanced diet and taking supple-
ments may not be the entire answer. Pancreatic digestive enzymes each
do a specific job and digest a specific food group. Individuals deficient in
lipase probably won’t digest fats and oils properly and won’t fully absorb
oilsolublenutrientslikevitaminsA,DorE.Thosedeficientinlactase
won’t digest lactose and may be lactose intolerant. Other people may
have a shortage of starch digesting enzymes or protein digesting en-
zymes. When this is the case, usually digestive discomforts such as bloat-
ing or indigestion are present to help the parent or physician recognize
the problem. When these situations are present, then supplementing
with the proper digestive enzyme product may improve poor nutrition.
Products to Correct a Poor Nutritional Profile
The selection of products used to correct a poor nutritional profile
should be based on the individual’s needs and how aggressive an ap-
proach the individual or parent wishes to take.
If the patient is extremely sensitive or seems to have severe gastroin-testinal issues, the less aggressive approaches would be recommended.
Regardlessofwhichapproachisutilized,beginwithabouta1/4dosefor
a few days and gradually work up to the recommended dose. This will
minimize any potential side effects or sensitivities.
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The most aggressive approach to correct a poor nutritional profile
wouldbeaformofSuperNu-Thera®,thehighB-6/magnesiummulti-
vitamin/mineraldevelopedbyDr.BernardRimland.Manyclinicalstudies
with positive outcomes have been done on this type of product using a
variety of subjects. Super Nu-Thera® comes in liquid, powder, capsule
and tablet forms, some flavored and others hypoallergenic in nature.
The hypoallergenic forms are generally recommended due to the ex-
treme sensitivity of many patients to flavoring agents and sugars. Some
children, however, need the product flavored in order to get compliance
sothoseformsarealsooffered.AdosagechartbasedonDr.Rimland’s
initial recommendations is enclosed with Super Nu-Thera® orders and is
outlined below. The dosage is based on weight.
This dosage chart only refers to the three original forms of Super Nu-
Thera®: powder, liquid, and caplets. Some newer forms of the product
such as Nu-Thera® and hypoallergenic capsules do not correspond ex-
actly. In those cases, the product labels or Kirkman’s customer service or
technical departments can be of assistance on the correct dosage.
Asmentionedbefore,alwaysstartbygivinga1/4doseforafewdays
and gradually increase the dosage every few days until the desired dosage
isreached.SomedoctorsrecommendlessthanDr.Rimland’ssuggested
dosage.
Super Nu-Thera® and Nu-Thera®products are available in various tastes
and textures.
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A less aggressive approach may be tried utilizing Nu-
Thera®, which is a condensed form of Super Nu-Thera®. It
consists of the same basic nutrients at lower potencies in an
easytoswallow,small,#3capsule.Thisproductishypoaller-
genic and has less taste impact if the capsule is opened and
the powder is mixed in food or drink. Another product suit-
able for a middle-of-the-road approach is Thera Response, a
hypoallergenic,mid-potency,multi-vitamin/mineralproduct
formulated at the request of several physicians desiring a
mid-potency product.
The least aggressive plan would be to use a standard
multi-vitamin/mineralproductsuchasourChildren’sChew-
ableMulti-Vitamin/MineralWafersorChildren’sMulti-Vita-
min/MineralHypoallergeniccapsulesandaddthevitamin
B-6andmagnesiumgraduallyusingKirkman’sVitaminB-6/
MagnesiumChewableWafersorP5P/MagnesiumGlycinate
capsules.EachB-6chewablewafercontains50mg.ofB-6with25mg.of
magnesium. Start with one daily and work up to as many as five daily ,
provided the increased dosages seem to be improving the child.
Byusingmulti-vitamins/mineralswithhighB-6/magnesiumcontent,you
are also trying an intervention that addresses behaviorial, learning and
social issues, as well.
Regardless of which approach you use, if the individual is on a casein-
freediet,besuretoaddacalciumsupplementsupplyingatleast800mg.
daily. Kirkman has calcium supplements available in powder and capsule
forms.
How Long Should I TryThese Products?
You should use the products for
at least four weeks in order to pro-
vide an opportunity for an improve-
ment to be seen. If no results are
seen,thehighB-6/magnesiumpor-
tion can be dropped, and you can
revert to a more standard potencymulti-vitamin/mineralproduct.
AddB-6orP-5-P/Magnesiumto a good multi-vitamin.
Nu-Thera® and Thera Response offer mid-potencies.
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The Gluten-Free/Casein-Free Diet Explained
Many individuals find it necessary to go on a
gluten-and/orcasein-freedietasaresultoffoodallergies or medical conditions. Whatever the rea-
son,managingagluten-free/casein-free(GF/CF)
diet is not as easy as it sounds. One must learn
which products contain casein and gluten and
get used to carefully reading product labels. In
addition, one must learn where casein and gluten
can “hide” from the consumer’s view on a la-
bel. Once the parameters are understood, what
seemed like an impossible diet to comply with
becomes much more tolerable and manageable.
How Long Must I Use theGF/CF Diet?
The trial period should be about six months. If
significant improvement results, the diet could
prove to be a lifelong necessity. If no improve-
ments are noted, then obviously the diet need
not be continued. Be sure to use caution in your
evaluation, because sometimes improvements are
slow and subtle, and going off the diet can cause
some regressions.
Vegetablesareasourceofgoodnutrition on special diets.
SPECIAL DIETS
The individual may already be on a special diet before trying
to correct poor nutrition. If so, certainly stay on track if it has
improved the individual’s health, which it does in many cases. If
a special diet is not being used, this is a “must” to try. The mostpopular diet with the greatest success rate is undoubtedly the
gluten-free/casein-free(GF/CF)diet.AllofKirkman’sproductsare
casein- and gluten-free for this reason.
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Casein Restriction
Caseinispresentindairyproducts.Eliminatingcaseinsoundssimple—
just remove all dairy products from the diet including:
• Milkinallforms(includingskim,powderedand
goat’smilk)
• Butter
• Cheese
• Yogurt
• Lactose
• Whey
• Caseinates
Unfortunately,itisnotthatsimple.Mostpreparedfoodscontaindairy
products such as powdered milk, cheese or whey. Soup mixes usually
do, as well. You must read the labels carefully to be sure dairy products
are not present in frozen or canned foods. You must also check bakery
goods and snacks for the presence of the
above casein sources. Reading the labels is a
critical issue.
There are acceptable casein-free sub-
stitutes available. Milk alternatives made
with rice, potato or soy are commercially
available in specialty sections of grocery or
health food stores. Some sensitive individu-
als also react to soy, so be careful on this
issue. There are also dairy-free yogurts and“mock”cheeseproductsmarketed.Using
your imagination along with these specialty
products will allow you to create your own
versions of recipes that traditionally contain
dairyproducts.A1998bookbyLisaLewis,
Ph.D.entitledSpecial Diets For Special Kids
gives hundreds of valuable creative ideas for
casein- and gluten-free diets.
Eggsandmosttypesofmayonnaisedonotcontaincasein.Thereare
also dairy-free margarines available, but read the labels carefully becausesome contain whey.
Special diets require that youread all food labels carefully.
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Gluten Restriction
Gluten restriction is more difficult and requires more effort than casein
restriction. It is also easier to be “fooled” because gluten can be hidden
in a lot more products. The following grains contain gluten and must be
avoided:
• Wheat
• Oats
• Barley
• Rye
• Semolina
• Spelt
• Triticale
• Kamut
These grains are present in most commercial cereals, breads, flours,
baked goods, instant mixes and prepared foods. Reading the label care-
fullyismandatorytoensuretheirabsence.However,thisoftenbecomes
challenging because natural or artificial flavorings along with spices,
gravies and dressings can also contain gluten. If in doubt, you will have to
check with the manufacturer of the product.
Fortunately, there are safe, alternative grains and flours for gluten-free
diets. Acceptable grain substitutes are:
• Sweetrice
• Brownrice
• Whiterice
• Tapioca• Potatostarch
• Beansflours(GarfavaandGarbonzos)
• Lentil
• Corn
Another factor that makes gluten-free dieting difficult
is the “contamination factor.” For example, wheat flour
makes a very good anti-caking or anti-stick compound for
some manufactured or packaged products and is not listed
on the label because it is not a component of the actual
product. Rather it is used to “dust” the manufacturing orpackaging equipment to prevent tackiness. Also, a fac-
tory that packages a gluten-free product may use the same
packaging line as it did for one containing gluten without a
thorough cleaning in between. Know your supplier and, if
Kirkman’s non-porous, washable
production rooms can be completelywashed down after each operationassuring a completely casein and glutenfree manufacturing facility.
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in doubt, call and ask about potential contaminations and request a copy
of the supplier’s standard operating procedures, which should outline
how their equipment is cleaned. If the supplier or manufacturer will not
share this information with you, chances are they are hiding something.
If everyone in the family is not gluten-free, be careful of in-home
contamination from pots, pans, cutting boards, utensils, countertops and
dishes. Most individuals sensitive to gluten are sensitive at minute levels
(afewpartspermillion).Whatmightseeminsignificantsuchaswheat
residue on a breadboard could have serious repercussions to the gluten-
sensitive person.
Aswithcasein,LisaLewis,Ph.D.,hasextremelyvaluableandcreative
ideas for gluten-free cooking in Special Diets For Special Kids. This publi-
cationisremarkablyhelpfulinunderstandingandimplementingaGF/CF
diet.ManyparentsbeginningtheCF/GFdietworryaboutfindingenough
foods which are “legal” for the diet but still nutritious and fulfilling for an
individual. These alternatives are described in this book.
Frequently Asked Questions about the
GF/CF Diet
Q:Doesn’teveryoneneedtodrinkmilktogetcalcium?
A:No.Calciumisavailablefromnon-dairysourcessuchaspotato,rice
or soy milks, plus calcium supplements can be used to ensure the daily
recommended amount is consumed.
Q:Don’tallchildrenneedmilktobehealthy?A:TheAmericanDairyAssociationhasledparentstobelievethat.The
truth is, children do very well without milk, as long as calcium require-
ments are obtained elsewhere.
Q:Whatelsebesidesmilkhascasein?
A:Allformsofmilk(powdered,goat’s,skim)pluscheese,butter,cream
cheese, cottage cheese, whey and caseinates contain casein.
Q:Whatcontainsgluten?
A: Wheat, oats, barley, rye, semolina, some food starches, alcohol from
grain, spelt, and kamut contain gluten. A lot of prepared packagedfoods contain gluten as do many restaurant foods. Flour, crackers, and
snack foods also generally contain gluten.
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Q:MychildonlylikesMcDonald’sChickenMcNuggetsasaprotein
source.Dotheyhavegluten?
A: Yes, they are rolled in wheat flour before frying. You can make your
own nuggets, however, using rice flour or bean flour. These are gluten-
free.
Q:DoFrenchfrieshavegluten?
A: Only if wheat flour is used as an anti-stick agent. Ask the restau-
rant. Also be careful about the possible contamination with gluten if
the fries are cooked in pre-used frying oil.
Q:Dovitaminsandothersupplementshavecaseinorgluten?
A:Theycan.Checkthelabel’slistofingredients(required)andcheck
for milk products like caseinates, lactose or whey, and for any grains or
starches that could contain gluten. Also, some flavorings can contain
gluten. Kirkman products are all casein- and gluten- free.
Q:I’veremovedcaseinandglutenfrommychild’sdietandhe/shestill
seemstobeallergictofoods.Whatdoesthismean?
A: First, check to make sure no hidden casein or gluten could be pres-
ent. Some individuals are also allergic to other ingredients such as soy
and corn. Ask your doctor to check this out.
The Specific Carbohydrate Diet (SCD)
This diet has been tried on individuals who have severe gastrointestinal
discomforts such as bloating, gas, diarrhea, constipation and severe food
intolerances.
TheSCDdietlimitstheintakeofsugarstosimplemonosaccharidessuch
as honey, fructose and dextrose, and eliminates the intake of disaccharides
and polysaccharides such as sucrose, molasses, mannitol, sorbitol, xylitol and
inulin. It also greatly restricts the consumption of starches and other types
of carbohydrates. The theory behind the diet is based on the assumption
that toxic organisms present in the gut thrive on disaccharides and starches,
and that their elimination will starve out these organisms. The main foods
consumed on this diet are, therefore, protein, vegetables, fruits, seeds and
nuts.AbookonthisdietbythelateElaineGottschallisentitledBreaking
the Vicious Cycle: Intestinal Health Through Diet.
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Signs of Gastrointestinal Disturbances
There are many distinct, recognizable signs of gastrointestinal distur-bances, but if the individual is unable to communicate the signs may not
be obvious to the caregiver. Some of the signs are:
Abdominal discomfort or cramping (often includes crying, scream-•ingorholdingtheabdomen)
Constipation,diarrhea,oralternationbetweenthetwo•Indigestion, bloating, gas•Inadequate digestion evidenced in stools•No formed stools•Inflammation•Yeast or bacterial overgrowth•Serious food sensitivities•
When gastrointestinal disorders are suspected, a thorough examination
by a gastroenterologist is called for. The evaluation very well may include
THE IMPORTANCE OFGASTROINTESTINAL HEALTH
Cleaningupthegastrointestinaltractisimperativeinsensitive
individuals. One of the special diets above may be a very goodstart in many patients, but may not complete the job.
Physicians have known for centuries that a well-functioning gas-
trointestinal tract and digestive system are crucial to good health.
When digestion is working optimally, other organs and systems in
the body have a better chance of working optimally, as well. This
is because the digestive system is responsible for processing the
nutrients in our food, which in turn are used for growth, repro-
duction, development, tissue repair, healing, and for the normal
functioning of every organ in the body. Therefore, the digestive
system is very much responsible for supporting the health of thebody as a whole.
In addition to providing fuel for the body through nutrition, the
intestinal tract also plays an integral role in the functioning of the
immune and nervous systems. This association is often referred to
as the “gut-brain connection.”
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an endoscopy and biopsy. Based on this evaluation, the physician has
many options to help. These options may include:
Prescription anti-fungals, antibiotics, or other drugs•OTCmedicationsorsupplements•SpecialdietsincludingGF/CForSCD•Probiotics to support good flora and crowd out undesirable or-•ganisms
Products that support tissue healing•Digestiveenzymes•
The Intestinal Immune System
The intestinal tract represents an important bar-
rier between the external world and the internal
environment, and there are a number of immune
mechanisms built into the gut lining that help en-sure that invading organisms from the outside are
neutralized before they can do potential damage
insidethebody.Itispostulatedthatupto70%of
the body’s immune system is associated with the
digestive tract. This intestinal immune system is
knownasGut-AssociatedLymphaticTissue.
When the specialized immune cells that line
the digestive tract detect an unknown or possibly
harmfulsubstance(calledanantigen),theysignal
the immune system to provide antibodies to helpfight these antigens. Another immune defender
that is present in the lining of the gut wall is
knownasSecretoryImmunoglobulinA(SIgA).
When antigens are present, SIgA can help to trap
them in the mucous layer of the intestinal tract,
thereby rendering them ineffective. The immune
system has an integral involvement with the di-
gestive system, and imbalances of the gastrointes-
tinal tract often occur concurrently with immune
dysfunction. Further discussions of the immune
system will follow later in this guide.
Optimal digestion positivelyimpacts other body systems.
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Gastrointestinal Tract: A Top Priority
Because of its involvement in the rest of the body processes, the gastro-
intestinal tract should be the top priority in getting proper care for sensi-
tive individuals. Without the proper functioning of the GI tract, trying to
correctotherareasmaybefutile.Discussthisprioritywithyourphysician
earlyinyourassociation.Priortoanexaminationbyaphysicianand/oragastroenterologist, one can very safely try a special diet, a comprehensive
probiotic or a digestive enzyme to help alleviate gastrointestinal discom-
forts. Often these interventions improve the quality of life for the indi-
vidual by improving overall health, gastrointestinal status and discomfort
related behavioral issues.
Digestive Function
Closelyrelatedandsometimesconcurrentwithgastrointestinaldis-
comforts are digestive irregularities. These are often present when thegastrointestinal tract is not healthy.
The primary function of the digestive tract is to break down the large
particles of food that we eat into small molecules that can cross over the
intestinal lining, enter the bloodstream, and become fuel for the various
metabolic processes in the body. In
order to accomplish this function,
the intestinal tract is involved in four
primary activities: digestion, absorp-
tion, assimilation and elimination.
Digestionisthebreakdownofthefood particles into usable nutrient
forms. Absorption is where those us-
able nutrients cross the gut wall and
pass from the intestine to the blood-
stream. Assimilation is utilization of
the products of digestion for energy
and the body’s metabolic processes,
while elimination is, of course, the ex-
cretion of the body’s waste products
through the intestines and kidneys.
Digestionbeginsinthemouthwithsalivarysecretions,thencontinues
in the stomach where secretions of hydrochloric acid and pepsin form a
material called chyme. The pancreas then releases enzymes into the duo-
denum of the small intestine as the chyme also passes into the duodenum
Digestionbeginsinthemouthwithsalivarysecretions.
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Digestionandabsorptionthencontinuesandisessentiallycompletedin
the small intestine. The final stage of digestion is completed in the large
intestine and colon where waste accumulates and is then eliminated.
Digestive Enzymes
Digestivefunctionirregularitiesareprevalentinsensitiveindividuals.
The majority of these are the result of the stomach not secreting enough
hydrochloric acid or the pancreas not releasing enough pancreatic diges-
tive enzymes. When these situations occur (and they often occur togeth-
er),supplementaldigestiveenzymesareoftentriedtohelpsupportthe
insufficiencies.
When we talk about supplementing with digestive enzymes, it is the
pancreatic enzymes that we are talking about. These are the enzymes
that have specific jobs and act only on specific types of food substrates.
When digestive enzyme supplementation is called for or recommended
by a health professional, it is imperative that the proper combination ofenzymes is chosen so as to address the problems at hand. For example,
lipase only digests fats; it does not act on proteins or sugars. Sucrase only
digests sugars; it has no effect on fats or proteins. Proteases and pepti-
dases act on protein, casein and gluten -- other enzymes do not.
Digestive Irregularities
There are many recognizable indicators that digestive discomforts are
present in an individual. Some of these can be:
Bloatingand/orabdominalpainorcramping• Irregular bowel habits or abnormally loose or mushy stools•Constipation,diarrhea,oralternatingbetweenthetwo•Discomfortaftereating•Excessivegas•Extremesensitivitytodairyandgrains•Veryodorousbowelmovements•Undigestedfoodinthestool•Oily,greasy,and/orfloatingstools•
As discussed earlier, a specific enzyme combination must be selected
based on an individual’s specific needs. There are many different enzymeproducts in the marketplace including :
Lipase-addressesfatdigestion•Lactase-aidslactoseintolerance•
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Peptidase/Protease-digestproteinsandpeptidesincludingcasein•and gluten
DPPIV(Peptidase)-targetscaseinandgluten•Multi spectrum enzymes - digest all food groups•Carbohydratedigestingenzymes-addresscarbohydrates•
If you know that a person needs a specific enzyme, such as lipase for
fats,youcanlookforthatspecificenzyme-containingproduct.Ususally,
however, individuals are not sure, in which case a multi-spectrum diges-
tive enzyme would be the product of choice. Multi- spectrum enzyme
products help digest all food groups including proteins, fats, starches and
other carbohydrates, sugars, celluloses and fiber.
Kirkman has advanced digestive enzyme products containing Isogest®,
a patent pending enzyme component with isomaltase activity. No other
commercially available enzymes contain the Isogest® fraction. Kirkman
Enzym-CompleteII/Isogest®formulaandMaximumSpectrumEnzym-
CompleteIIDPPIV/Isogest®Formulaarethetwoproductsofchoice.The
latter product is fruit-free, which is important in those individuals sensi-
tive to pineapple or papaya fruit.
No other commercially available enzymescontain the Isogest® fraction.
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How Long Should the Trial Period be on Enzymes?
Improvements of the digestive symptoms should be quite rapid. If no
improvements are noted in about four weeks, supplementation can be
stopped.
Probiotics
Often, enzyme insufficiency is accompanied by a poor ratio of gut flora
present in the intestinal tract. A healthy intestinal tract normally has a
good balance between healthy, desirable flora and unhealthy bacteria
or yeast, while a compromised intestinal tract lacks this good balance of
flora. In these instances taking a probiotic with the enzymes is a pos-
sible solution and helps maximize the enzyme activity. The probiotics are
blends of beneficial flora that set up residence in the small intestine and
help to crowd out the unwanted organisms. When enzymes and probiot-
ics are taken together, it is recommended that the enzyme be taken at the
very beginning of the meal with the probiotic following about one halfhour later. When enzymes are not being used concurrently, the probiotic
should be taken at the beginning of the meal.
How Long Should the Trial Period be on Probiotics?
The trial period on probiotics should be about two
months because it takes time for the organisms to set up
residence and begin crowding out the unwanted organ-
isms. As a result, the improvements can be quite gradual
and subtle. Improved stools and fewer digestive symptoms
should be evident after the trial period.
Probiotics are beneficial bacteria that helpcrowd out unwanted bacteria.
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IMMUNE SUPPORT
General Facts About Our Immune System
The immune system is a complex and dynamic network of many
soluble components including cells, membranes, and a mini circulatory
system separate from blood vessels. These entities all work together to
protect us from infection by opportunistic microbes, bacteria, viruses,
fungi and parasites that abound in our environment. The immune
system also constantly scans our bodies for any signs of abnormal cell
growth.
Our body’s first line of defense
against unwanted intruders consists
of our skin, our body enzymes, such
as saliva and stomach acid, and our
protective epithelial cells, which line
our body’s mucosal surfaces. These
physical factors combined with spe-
cialized white blood cells make up
our innate immune system, which is
rather non-specific and broad- spec-
trum in nature.
More complicated is our body’s
adaptive immune system, which is
far more sophisticated and deals
with specific fragments of any potentially harmful or foreign material.
These fragments are called antigens and they are dealt with in the im-mune system by antigen receptors. Once an antigen receptor adapts to
one of these invading fragments, it retains antigenic memory so that it
may quickly neutralize that antigen if it invades the body again.
There are many specialized white blood cells that work together
to coordinate overall immune response. “T” cells are responsible for
cellular immunity while “B” cells produce antibodies in response to
antigens. Then there are NK – natural killer cells that kill off certain
infected targets, granulocytes, which remove bacteria and parasites by
releasing toxic compounds, and macrophages that engulf and destroy
foreign material.
TherearetwomajortypesofTcells:Th1andTh2.Th1cellsdrive
immunogenicresponses,whileTh2cellsdriveantibodyproductionbyB
cellsandareespeciallyimportantinrespondingtoallergens.Compro-
Pictured are viruses attacking healthy cellsin the blood.
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misedimmunesystemsusuallydisplayaTh1toTh2cellshiftthat
causes an increase in food and environmental allergies .
The success of our immune system relies on an incredibly elabo-
rateanddynamicregulatory/communicationsnetworkcomposed
of millions of cells and is a sensitive system of checks and balanc-
es. Genetic make-up and environmental invasions can result in
the immune process going terribly wrong. Serious infections and
other health consequences can result.
Frequent illness may be a sign of aweak immune system.
Signs of Immune Deficiencies
The signs of an immune problem are often quite easy to recognize
over time. Persistence of the following conditions are key to suspecting
immune deficiencies:
Frequent illness•Continuousfoodallergiesoranincreasednumberof•such allergies
Inadequate detoxification as indicated by laboratory testing•Lowglutathionelevelsasindicatedbylaboratorytesting•Impaired methylation•
Sensitive individuals are especially prone to immune problems. In the
case of children, parents’ observations conveyed to the physician are ex-
tremely important in helping the doctor recognize the problem, which is
often hard to judge at an office visit.
There is a long list of nutritional products that support a healthy im-
mune system including :
Zinc•VitaminA•VitaminC•VitaminE•Selenium•Beta Glucan•CoenzymeQ-10orIdebenone•N-AcetylCysteine•Colostrum•CranberryExtract•Garlic• Kirkman carries a wide variety of
products that support the immunesystem.
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OliveLeaf•Goldenseal•ReducedL-Glutathione•DimethylglycineorTrimethylglycine•
You may recognize some of the above nutrients as being present in the
multi-vitamin/mineralyoumaybeusing.Tobettersupportacompro-
mised immune system, additional supplementation of the nutrient is rec-
ommended.Increasingzincto50mg.daily,vitaminCto1000-3000mg.
daily,vitaminEto200-400IUdaily,seleniumuptoatleast75mcg.daily,
andCoenzymeQ-10upto100mg.dailymaybebeneficial.
Kirkman also carries other combination products comprised of many of
the above immune boosting nutrients.
Sleep Issues
Sleep issues in sensitive individuals are not much different from sleep
problems in the general population. These can include:
Trouble falling asleep•Periodic night awakenings•Restlessness•Nightmares•
It must be remembered, however, that these sleep tendencies could be
all or in part due to underlying conditions such as digestive issues, gastro-
intestinal tract issues such as ulceration, reflux, or inflammation or othercauses of pain.
The dietary supplements often useful in supporting restful sleep are:
Magnesium•Melatonin•L-Taurine•GABA•
All of these supplements are safe and usually without side effects, and
should be tried one at a time for about a week in the order listed above.
If one supplement does not seem to help, stop and try the next one .
Kirkman’s sleep support products in-cludeMagnesium,Melatonin,L-Taurine,and Gaba
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Sulfation
The sulfation process is linked to an enzyme system known as phenol
sulfotransferase(PST).Normally,PSTisinvolvedinaprocesscalledsulfo-
conjugation, whereby a group of potentially harmful chemicals known as
phenols are attached to sulfate and thereby eliminated from the body.
When there is a deficiency of sulfate in the bloodstream, phenolic com-
pounds may build up in the body, and this in turn can interfere with neu-
rotransmitter function. Sulfate deficiency and the resulting impairment ofPST activity may explain some sensitivity reactions to a variety of phenol-
containing foods, such as apples, grapes, chocolate, food colorings, and
some herbs and spices.
Verysensitiveindividualsseemtohaveonlyabout1/5thofthenormal
level of sulfate in their bodies, the rest having been excreted excessively in
the urine. In addition to the phenolic buildup described previously due to
sulfate deficiency, sulfur and sulfate also play other important roles in the
body including:
• Detoxificationprocesses• Releasingcertainpancreaticdigestiveenzymes
• ActivatingthehormoneCCK
Sulfationcanoftenbesupportedbyoralsulfate,topicalEpsomsalt
products,orbygivingindividualsEpsomsaltbaths.Magnesiumsulfate
productsandEpsomsaltbathsareperfectlysafeinterventionsthatcanbe
tried at home without concern by simply following the label instructions.
Methylation
Methylation is a series of very important biochemical reactions in the
body that are responsible for overall good health. In sensitive individuals,
this process is very often lacking to some degree, making these individu-
BIOCHEMICAL PATHWAYS
Sensitive individuals often exhibit certain tendencies in sever-
albiochemicalpathways.Eachoftheseindividualpathwayshas
a unique purpose and an abnormality can lead to health issues.
A description of those pathways most often disrupted follows.
Many individuals with sensitivities havereduced sulfate levels in their body.
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als poor methylators. A properly functioning methylation pathway has
rewarding health benefits including:
Proper brain function•Healthydetoxification•Proper reproduction•DNAprotection•Healthy,normal,non-prematureagingprocess•
There are many nutritional supplements that support proper methyla-
tion. You should discuss these options with your physician carefully, be-
cause each individual is unique and requires a methylation improvement
program specifically tailored to his or her requirements. Products your
doctor may use to support the methylation process include:
MethylVitaminB-12•DimethylglycineorTrimethylglycine•Folic or Folinic Acid•VitaminB-6•SAMe•Selenium•Zinc•Phenol reducers•
The methylation pathway is complicated and a physician should
be consulted to determine interventions.
Oxidative Stress
Individuals with dietary sensitivities can have elevated oxidative
stress.Certaintoxinscalledoxidantsenterthebodyandbegin
causing oxidative tissue damage known as oxidative stress. These
toxins can be in the form of chemicals, pesticides, heavy metals,
and other environmental pollutants. Some of these cell-injuring
oxidants are known as “free radicals.” It is important to minimize
oxidative stress damage by consuming antioxidants, which retard
theprocess.SomeoftheseantioxidantsincludevitaminsC,E,and
A, selenium, melatonin, carnosine, carnitine, pycnogenol, grape-
seedextractandCoEnzymeQ-10.Therearelaboratorymarkers
that measure levels of antioxidant compounds present in the body.Talk to your doctor about appropriate testing and subsequent
supplementation with antioxidants.
Kirkman offers a wide range of antioxidantsto support those with oxidative stress.
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The most common behavioral disturbances involve the following symp-
toms:
Speech delay or absence of speech• Unabletoputwordsorsentencestogether•Learningdisabilities•Lackofsocialskills•Lackofeyecontact•Aggressive behavior•Passive behavior•Depression•Anxiety•Tics or abnormal neurological responses•
The list of supplements and interventions that have been used in deal-ing with these behavioral issues is long. Some of the more popular ones
include:
HighB-6/magnesiumsupplements•Highpotencymultiplevitaminsandminerals(somemayinclude•higherB-6/magnesiumpotenciesaswell)
DimethylglycineorTrimethylglycine•Taurine•Carnosine•Creatine•
Inositol•Omega-3fattyacids•Codliveroil•HBOT(HyperbaricOxygenTherapy)•CoenzymeQ-10orIdebenone•
BEHAVIORAL CONSIDERATIONS
Behavioral disturbances are very common in diet sensitive
individuals. Because each individual is different and displays dif-
ferent behavioral traits, it is challenging to find the right inter-
ventions for a given person. Often, laboratory test results areof no value here because what causes one individual to behave
a certain way may have quite a different effect on another.
Sometimes doctors and parents are forced to use trial and error
evaluations of various interventions until the correct regimen is
found for a given patient.
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Youmayhavealreadytriedthemulti-vitamin/mineralsupplementation
withhighB-6/magnesiumasyourfirstinterventionsoyouwillhaveevalu-
ated its effectiveness.
Often lack of eye contact due to insufficient vitamin A in the diet can
beimprovedbycodliveroil,asdemonstratedbyDr.MaryMegsonof
Richmond,Virginia.
Generally, a thorough examination by your physician is preferred before
any of the above interventions are begun, however many of the products
listed are perfectly safe and present no side effects when taken. So in
cases when a physician is not available for a period of time, vitamins, min-
erals,omega-3fattyacids,codliveroilandCoenzymeQ-10arecertainly
harmless to try and could prove very beneficial. It should be remembered,
however, that only one product should be tried at a time.
Otherinterventionslikedimethylglycineortrimethylglycine,HBOT,
creatine, carnosine and inositol normally require a physician’s involvement
for maximum safety.
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TOXIC LOAD/HEAVY METALS
Substantial evidence is emerging linking many medical conditions
to negative environmental influences present in our world. Negative
environmental factors have been implicated in a myriad of medical
irregularities. The frequency of many of these medical conditions is
increasing, which leads to further speculation that outside environ-
mental causative factors are involved.
Included in the list of environmental insults that can affect disease
statesaretoxicchemicals,heavymetals,PCBs,andpesticidespresent
in the products we use, and contaminants in the air we breathe and
the water we utilize and drink.
These environmental pollutants can affect the body in numerous
ways. Natural body defense mechanisms such as immune response
can be bombarded with the insults, thereby becoming less effectivebecause of the toxic load.
Another area of intense research is how environmental factors af-
fect the genetic makeup of an individual. There are many genes in
our body that are considered “environmentally responsive,” which
means that they can be altered by environmental factors. If you
alter a gene’s makeup, the potential exists for changing the normal
development of a person. Some of these changes can be immediate
andsomemaytakemanyyearstomanifest.Dependingonwhich
gene is involved, an individual can become vulnerable to changes in
metabolic pathways, physical development, immune response, braindevelopment and function, and nervous system development and
function.
What Could be Signals of a Toxic Load Burden?
The following symptoms could be present as a result of toxic burden:
Learningorspeechdifficulties•Lackofsocialskills•Aggressive behavior•Passive behavior•Poor immune response•Biochemical pathway issues•
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Kirkman Kleen™ personal care and cleaningproducts lines were designed without harshchemicals, allergens or toxins.
Minimizing the Toxic Load
Sensitive individuals often have severe toxic burdens. This can be com-
pounded by the fact that a biochemical pathway known as methylation is
often compromised. A doctor’s evaluation is needed to determine if this
pathway is not working properly. Nutritional interventions can support
improvement of this condition.
Certainnutrientsareconsiderednaturaldetoxifiersandcanhelpmini-
mize the negative impact of toxic exposures and enhance the body’s natu-
raldetoxificationprocess.Examplesofsuchvitaminsandmineralsarezinc,
vitaminC,vitaminEandselenium.Othernutritionalfactorsthatcanbe
helpful are taurine, N-acetyl cysteine and glutathione.
Being selective about the products we use or the foods we eat can great-
lyinfluenceourtoxicload.TheFDAhasalreadyissuedwarningsabouthow
muchfishweshouldeatbecauseofthemercurycontent.Usingotherfood
products or dietary supplements with ultra high purity - such as those witha hypoallergenic designation - is another means of minimizing our toxic
load. This is also true for personal care products and cleaning agents we
use. And don’t forget about the air we breathe and the water we drink
and cook with. The purer our water and air, the less environmental con-
tamination. Numerous air and water filtration products are available to
improve air and water purity. Kirkman has recently introduced the Kirk-
man Kleen™ line of personal care and cleaning products that are formulat-
ed with safe ingredients so as not to contribute to a toxic load in the home.
Detox-Aid Advanced Formula
When environmental toxins are encountered by the body, a detoxifica-
tion process must occur to prevent a toxic overload. In sensitive individuals,
the detoxification pathways are often compromised requiring the system to
obtaina“boost”fromtheoutside.Kirkman’sDetox-AidAdvancedFormula
was specially formulated to provide that “boost” to help support the body’s
natural detoxification processes.
How Does Detox-Aid Advanced Formula Work?
TheingredientsinDetox-AidAdvancedFormulaandhowtheyworktohelp the detoxification process are described below:
As toxins become active in the body, glucuronic acid combines with•the toxins to form a non-toxic molecule called a glucuronide which
can be excreted into bile, thereby eliminating the toxin. An en-
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zyme called beta-glucuronidase present in the body largely as a by
product of intestinal flora can disassemble that non-toxic molecule
whichthenfreesuptheactivatedtoxinagain.CalciumD-glucarate
acts to prevent that disassembly process of the glucuronide by
becomingD-glucaro-1,4-lactone,thedirectinhibitorofthebeta-
glucuronidase. Without this inhibition process, the cleaving of the
glucuronide would lead to the toxin being reabsorbed by the intes-
tinal mucosa.
Turmeric is a powerful antioxidant that increases the formation of•the detoxifying glucuronides. Turmeric’s antioxidant properties
also aid glutathione in doing its job.
ReducedL-glutathioneisrequiredbythebody’scellsinorderto•detoxify.
N-acetyl cysteine provides cysteine that is used in the body to form•glutathione,thebody’scelldetoxifier.Cysteineisalsothemajor
source of taurine that is produced by the body.
Taurine is an essential component of bile formation. Bile flow into•the intestinal tract is a major detoxifiction route in the body, along
with sweat, urine, breath, hair and nails.
Milk Thistle contains silymarin which is a very powerful antioxidant•that supports the protection of cells. It also supports liver function,
which is instrumental in body detoxification processes. In human
and animal studies, silymarin has exhibited its protective effects.
OliveLeafExtractispresentinDetox-AidAdvancedFormulafor•controlling the growth of undesirable intestinal flora that tend to
thrive in the presence of sulfur compounds such as glutathione and
N-acetyl cysteine.
Selenium is present due to the fact that it is an antagonist toward•ingested metals including lead, mercury, aluminum and cadmium.
Heavy Metal Detoxification
Detox-AidAdvancedformulaassistsinthebody’snaturalremovalof
ingested heavy metals and works synergistically with heavy metal detoxi-
fyingcompoundssuchasDMSA,EDTA,Chemet,andDMPS.Thesechelat-
ing agents should be used only under the supervision of a physician, as
laboratory testing must be routinely performed to monitor kidney, liver
and cell conditions.
You may be in the beginning stages of trying to eliminate toxins thatare present in our environment. We should all be doing that. Some will
remain, however, as we still have to eat, breathe and drink to sustain our
lives.Kirkman’sDetox-AidAdvancedFormulacanhelptoenhanceour
bodies’ detoxification processes.
Detox-Aidsupportsthebody’snaturaldetoxification processes .
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WehavealreadydiscussedtheGF/CFdiet,whichrestrictscaseinand
gluten in an individual’s diet. Other dietary restrictions may be necessaryfor sensitive individuals or individuals with special dietary requirements.
These may include soy, corn, rice, sugar, egg or preservatives.
As we work with parents and doctors in developing appropriate dosage
forms, it has become evident that many of our customers have extreme
sensitivities and allergies to many naturally occurring ingredients and
tonearlyallexcipients(inactiveingredients)
normally found in nutritional supplements and
traditional foods. It has always been Kirk-
man’s goal to formulate all products to be as
palatable as possible so as to make administra-tion and compliance easy, especially for the
parents. Some of the flavorings and formulation aids used to make these
products taste good are the very ingredients to which some of our cus-
tomers are sensitive.
Kirkman is committed to having a broad product line that will meet the
needs of all of our customers. To cover the needs of those children who
are extremely sensitive or allergic to many commonly used ingredients,
Kirkman has developed a full line of hypoallergenic products in two-piece,
hard-shell capsules. The capsule shell is made from plant cellulose, not
frombeeforporkgelatinasmostcapsulesare.Capsulesmanufactured
from beef or pork can contain potential allergens associated with animal
derived ingredients. Kirkman’s capsule shells, known as vegetable cap-
sules, are manufactured from plant cellulose derived from pine trees. This
fibrous cellulose is an inert material and is allergen free. Furthermore,
these hypoallergenic products contain no fillers, flavors, preservatives or
common formulating aids that could cause sensitivity or allergic reactions.
As a result, Kirkman’s hypoallergenic line is free of casein, gluten, soy, fla-
vors, colors, animal derivatives, sugar, heavy metals, pesticides and other
environmental impurities.
If you try some of the interventions discussed in this guide and seem to
notice a reaction or sensitivity to products that are flavored, colored or
contain potential allergens, it is strongly recommended that you try the
same product type in our hypoallergenic line. You may find that the reac-
tion or sensitivity disappears.
DON’T OVERLOOK THE
HYPOALLERGENIC FACTOR
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Why Aren’t All Products Made to be Hypoallergenic?
Most manufacturers of nutritional supplements provide products to
drug chains, food chains and mass market distributors. The majority of
the population is not sensitive to a common list of ingredients usually
called “pharmaceutical excipients.” Some of the most common ingredi-
entsonthatlistincludestearicacid,gelatin,eggs,dextrose(cornsugar),
corn starch, sucrose, polyvinylpyrrolidone, sodium chloride, milk or dairy
derivatives, wheat or grain derivatives, and soy. In addition, various fla-
vorings and colorings are often used.
For those individuals without sensitivities or allergies to these ingredi-
ents or the impurities present in those ingredients, no problematic side
effects become evident to the user. Manufacturers use these standard
ingredients because of cost and because they contribute to production
efficiency. As an example, capsule shells made from gelatin cost less than
half of those made from plant cellulose, plus production using animal
gelatin shells is often twice as efficient. The fillers and capsule produc-
tion aids Kirkman uses in our hypoallergenic line are the most inert
ingredients known and are selected so as not to contain known potential
allergens. In addition to the plant cellulose in the capsule shell, Kirk-
man uses non-allergen excipients such as silicon dioxide, various cellulose
gums,di-calciumphosphate,inulin(fromthechickoryroot),andL-leucine.
Vegetablegrademagnesiumstearatemaybeusedinminutequantitiesas
a lubricant when necessary.
Raw materials selected for Kirkman’s hypoallergenic line were selected
to be the purest available minimizing the content of heavy metal impuri-
ties such as lead, mercury, cadmium and aluminum. Other environmentalcontaminantsarealsoscreenedincludingpesticideandPCBresidues,and
bacterial and yeast levels are carefully monitored.
In formulating the hypoallergenic line, Kirkman used only one criteria:
providing the best non-allergen product line possible. Ingredient choice
and purity, plus the science behind those selections, were the only consid-
erations.Costandproductionefficiencieswerenotconsidered.Helping
the extremely sensitive individual was our primary goal.
What Have Been the Results of Individuals Using
Kirkman’s Hypoallergenic Line?
Individuals using the hypoallergenic product line have essentially elimi-
nated all sensitivities, allergies and reactions that had previously been an
issue. The response to these products has been phenomenal with physi-
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cians and customers from all over the world continuing to compliment and
thank Kirkman for developing this line that was so very much needed in
the world of dietary supplements. Individuals exhibiting sensitivities and
allergies have benefited greatly from this product line.
It is Kirkman’s goal to offer a hypoallergenic version of all products
developed in the future. This product line is a significant breakthrough in
allowing extremely sensitive individuals to get the supplements they need
without worrying about additives, allergens or impurities.
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35We have listed some ideas below that we compiled from our discussions
with parents. This is by no means the complete list. We encourage you to
experiment to find what works for you and your child.
Flavorfoodordrinks.(maple,cherryandstrawberry.)•Mix in orange juice•
Mix in lemonade•
Mix in red grape juice•Mix in pear juice•Mix in baby food prepared juices•Mix in Juicy Juice®•MixinV-8Splash®•Useyogurt•Usepudding•Usefruitsorbets•Try cocoa•TryHershey’s®syrup•
Try peanut butter, cashew butter or almond butter•
Make a fruit “smoothy” in a blender•Makeaproteindrink(riceorsoy)inablender•Mix in honey or jelly•Make popsicles that include the vitamins (especially good for the•SuperNu-Thera®powdersandliquids)
Put doses of the supplements in “rice crispy treats”•Sprinkle non-heat sensitive products on a pancake before flipping•Mix in ketchup and let the kids drag their French fries through it•Puttheproductsinscrambledeggs(afterthey’recooked)•Putproductsinspaghettisauce(afterit’sbeencooked)•
Hideproducts(especiallyliquids)in“boxdrinks”• IfyouuseCoromega®,addothersupplementstoit•Calcium,magnesium,othermineralsandFlax(EFA)canbeusedin•cooking and baking
Baby foods work great for hiding supplementsMix supplements in•Vance’sDari-Free™orothermilksubstitute
HOW TO GET YOU CHILDREN TO
TAKE NUTRITIONAL SUPPLEMENTS
Many of your children need to take numerous supplements at
once and at multiple times during the day. This becomes very chal-
lenging for the parents and, of course, the children. At Kirkman
we are asked regularly for ideas on how to administer the supple-
ments so that the children will take them.
There are many ways to help your child takenutritional supplements.
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APPENDIX A
Step-by-Step Recap of Interventions
There is not an absolute regimen that one should follow when begin-ning biomedical and dietary interventions in sensitive individuals, but
there are some logical sequences that a parent can follow until guidance
by a specialty physician is in place.
The Top Three Interventions to Try
Without question, the top three include:
1)Improvingnutrition
2)GF/CFdiet
3)Improvingtheconditionofthegastrointestinaltract
These top three can actually be tried in any order and all physicians may
notagreeastowhichorderisdesirable.Sosteps1,2,and3couldinvolve
in any order:
Super Nu-Thera® or Nu-Thera®•Thegluten-free/casein-freediet•Probioticsand/ordigestiveenzymes(amulti-strainprobioticsuch•as Pro-Bio Gold™ or Multi-Flora Spectrum™ would be a good
start,inconjunctionwithEnZym-Complete/DPP-IVIIwithIsogest®
formula)
Next Possible Steps
If sleep is an issue, the interventions listed for sleep improvement could
be tried as described in the Sleep Issues section.
If the symptoms of an immune problem are present, several of the prod-
ucts for immune support can be tried.
If vision support is needed, cod liver oil could be tried.
The More Complicated Interventions
When it comes to behavioral issues or metabolic pathway irregularities
such as methylation, sulfation and detoxification, a specialist physician
is really needed to assess the situation. Many complicated intricacies of
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physiology exist in this area , plus potential side effects must be moni-
tored.Amulti-vitamin/mineralsupplementwithhighB-6/magnesium
may have helped begin the process, but numerous other options are spe-
cific to the individual and require a medical examination and guidance.
Laboratory Testing
When you begin working with a specialized physician, he or she will
undoubtedly request laboratory tests that are specifically tailored to a
patient’sneeds.Examplesofthesetestsare:
• Urinarypeptides
• Urinaryorganicacids
• Foodallergypanel
• Plasmasulfate
• Stoolanalysis
• Toxicmetals
• Redbloodcellelements• Essentialfattyacids
• LymphocyteTH1/TH2
• Liverandkidneyfunction
• MyelinBasicProtein
• Ammonia
You probably won’t need all the tests, rather you may want to select
ones based on a medical evaluation.
Kirkman’s Customer Service Staff and TechnicalStaff Can Help
The journey through dietary and biomedical interventions is not an easy
one. Your doctor will be your main source of guidance as you progress.
Kirkman has been supporting parents on their journeys with their children
for decades. Please feel free to call our customer service or technical staff
if you need assistance .
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NOTes
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CustomerService(clockwisefromtopleft:Sonia,Kathy,Amy,Rhonda,Shirley,Melisa,Carrie,Kari-Jane,BethandRacheal.)
s u at www.kirkmana.om
6400SWRosewoodStreet
LakeOswego,Oregon97035
Telephone: (800)245-8282
(888)KIRKMAN
(503)694-1600
Fax: (503)682-0838
E-Mail:
Ordering: [email protected]:[email protected]
Technical Support: [email protected]
ServicioalClienteenEspanol:[email protected]
LineaDirectaenEspanol:(503)783-2714
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