kconnect - making medical information easier to find: semantic annotation and semantic search using...
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Research & Project Manager FINDWISE [email protected] @Peter_G_Voisey
Researcher & Principal InformaGon Strategist FINDWISE / Chalmers & GU [email protected] [email protected]
SemanGc AnnotaGon & SemanGc Search
Länkade data i Sverige 2016 #LDSV
Advanced search technologies for medical informaGon www.kconnect.eu
13 European partners: SMEs, UniversiGes & Health AuthoriGes
EU InnovaGon project to July 2017
Be]er use of medical informaGon
CollaboraGon between: Findwise – Qulturum – Medicinkliniken at Eksjö
KConnect at Region Jönköping
KConnect – The Aim • To provide be]er medical search for clinicians
& researchers in their daily lives
• Increase the ‘findability’ of informaGon not normally designed to be found
• To provide the most helpful & up-‐to-‐date
informaGon from silos to support decision-‐making
• To take advantage of the untapped hidden
textual informaGon within EHRs that give context and meaning
Knowledge Base [KB]
InformaGon ExtracGon [IE]
SemanGc AnnotaGon [SA]
SemanGc Search [SS]
Machine TranslaGon [MT]
Log Analysis Readability
Trustability
Medical Records EHRs
Medical
Publica2ons
Medical
Guidelines
Systema2c Reviews
Radiology Reports
Medical Websites
Flexible technology stack • 1.2 billion medical RDF statements
RJL use case architecture
Knowledge Base
Annotated texts
Search Inde
x
Text processing and machine reading
Search Service or API
LinguisGc processing
EHRs Publ. material
Research Other sources
Archives
Uniform terminologies linking informaGon across silos
Knowledge Base
Annotated texts
Search Inde
x
Links to the knowledge base
Search Service or API
LinguisGc processing
EHRs Publ. material
Research Other sources
Archives
Find documents that menGon
drugs
Knowledge Base
Annotated texts
Search Inde
x
Links to the knowledge base
Search Service or API
LinguisGc processing
EHRs Publ. material
Research Other sources
Archives
Find documents that menGon anG-‐inflammatory
drugs
Knowledge Base
Annotated texts
Search Inde
x
Links to the knowledge base
Search Service or API
LinguisGc processing
EHRs Publ. material
Research Other sources
Archives
Find documents that menGon drugs
used to treat headaches
Kunskapsbas
Annotera texter
Sökind
ex
Länka text Gll kunskap
Söktjänst eller API
språklig bearbetning
Journaler Publ. material
Forskning Andra system
Arkiv
Find documents that menGon drugs
used to treat diseases that affect
the kidneys
KConnect at RJL Use Case & Prototype development
"I want to know what the right treatment for a pa2ent's symptoms”
”I want to compile the best therapy exercises for a pa2ent with a sore knee to give the right treatment"
”Be=er knowledge of the symptoms & discomfort of illnesses Their descrip2on and iden2fica2on”
"Could these symptoms be cancer? Is there a way to access the risk of cancer?”
“Informa2on for Decision Support”
“The treatment basics” "What is best prac2ce? Who can or can’t do certain procedures?"
”How to know the best test(s) for the specific symptoms/condi2ons Be=er inves2ga2on? -‐ Be=er treatment”
”I want to know how to care for a person aOer surgery to ensure the right controls and care is in place"
Focus groups
How and when do you want informa2on? -‐ When you meet the pa2ents, before or aOer? What needs do you see for an IT system? What is important to you, for example: User friendliness? Easy access? Func2onality? Etc.?
Focus groups
Many informaGon sources to answer a quesGon
Internetmedicin
UpToDate
Pubmed/literature databases/Journals
PaGent’s EHR
Other medical/drug informaGon sources
NaGonal, Regional & Local guidelines
Access Medicine
Problem & Ques2ons
Oxford Textbook of Medicine
KConnect – search engine
Want to search in a patient EHR?
Journalutdrag etc.
Intagningsant.
Primärvård
What do you want help with daily?
Decision support
Do you want to which guideline to use?
National guidelines
Ex. FAKTA
Do want to know which the local guidelines to use?
PM
Riktlinjer Article 1.
Article 2.
Article 3.
Regional guidelines
Do you want to see the latest publications or medical literature?
What or how do you want to improve?
Improve knowledge
Care methods
Examples of best practice
Hjälp/Demo
?
UpToDate
Key KConnect concepts Smart(er) search
Complex queries
Finding unusual diagnoses
Support for new / inexperienced doctors
Fast searches under pressure
Reduce human error
More Gme with paGent
KConnect at RJL? • Live paGent E.H.R. ‘reading’ (overview from text analysis)
• Further medical search across many sources from a paGent E.H.R. view or accessed independently
• Search either before, during or aqer paGent consultaGon
• As a search tool for supporGng medical informaGon -‐ clinical trials, medical studies, treatments, guidelines (and later possibly across anonymised paGent EHRs)
• Facilitate the care process – the search engine knowledge base can give support in finding the best diagnosis and treatment
KConnect – How does it work? Based on
RJL permissions Ethics Patient privacy/security System & data access permissions Collaborations!
KConnect – via the PaGent EHR
KConnect – Results Page
Use Cases Jönköping v KCL, London
• Live analysis of paGent E.H.R.s and further invesGgaGon into medical literature, guidelines etc.
• To provide helpful informaGon in decision-‐making processes
• Future: Symptoms-‐Diagnosis (addiGons to KB) • Future: Search across anonymised EHRs
Jönköping
King’s College, London & South Maudsley Hospital (NHS)
• Analysis across pseudo-‐anonymised paGent E.H.R.s • ExtracGon of paGent types, disease, symptoms etc to databases • To predict Adverse Drug ReacGons (use of KB and new doctor RDF notaGon) • To evaluate risk of suicide in mental hospital paGents (pa]erns)
Visualizing the data (USFD/Prospector)
Occurrence of Keyword “influenza”
Most Searched Diseases by DieGcians
TACK
Research & Project Manager FINDWISE [email protected] @Peter_G_Voisey
Researcher & Principal InformaGon Strategist FINDWISE / Chalmers & GU [email protected] [email protected]
h]p://kconnect.eu h]ps://kconnectme.wordpress.com h]ps://www.linkedin.com/groups/3745929 �@KConnect_eu