jurnal waw ta
TRANSCRIPT
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REVIEW ARTICLE
THE EVIDENCE REGARDINGMAINTENANCE TOCOLYSIS
John P. Elliot and John C. Morrison
Perinatal services, Division of Southwest Contemporary Womens Care
Departement of OB/GY, !niversity of "issisippi "e#ical Center
Hindawi Publising CorporationObstetric and Gynecology International, Volue !"#$
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PE%&'H()('%
Persalinan
prematur Kriamniniti
s A!rupti
Plasenta
Kela"iranprematur # $i seluru"
$unia %SA &1'(
Mrtalitas )mr!i$itas
in*ant
T+lisis
?
'
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TOKOLITIK MAINTANANCE ORAL
E*e+ sampin,
E*e+memperta"an+an
+e"amilan
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*O+O)I*I+ M'I%*'%'%CE O')
.
/a,nis
Ma,nesiumral
Anta,nisPrsta,lan$
in
Anta,nis
Ca C"annel
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0 AGONIS
Creas et al
Rit$rin ral memperpan2an, usia ,estasi setela"pen,"entian persalinan prematur
Le3is et al
Ter!utalin ral4 ter!u+ti
Ma5nes et al
Ter!utalin ral 6 ma,nesium ral 4 memperpan2an, usia,estasi
Rust et al
'.7 pasien an, $ia5a+ 8ter!utalin9 ma,nesium9 plase!: tin,+at +ela"iran prematur serupa pa$a +eti,a +elmp+
;
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+anmemperpan2an, inter?al persalinan
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MAGNESI%M ORAL
Martin et alMa,nesium ,lu+nat 8' ,r6"ari: memperpan2an,
inter?al "in,,a persalinan $anmen,uran,i insi$en
!erulan,na persalinanprematur
Rust et al
Ma,nesium +lri$a ral 4per!e$aan $en,an plase!
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Terapi ral Se5ara
si,ni>+an
Ma,nesium ;;9.(
Ter!utalin=-9B(
$i"enti+an
E*e+ sampin, maternal$an *etal
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CALSI%M CHANNEL ANTAGONIS
Ni*e$ipin
Serin, $i,una+an se!a,ai pen,!atan persalinan prematura+ut Per5!aan +lini+ tera5a+ ti$a+ a$a per!e$aan "asil a+"ir
El sae$ etal
=B 3anita $iltiaem ral6 ni*e$ipin ral Inter?al 3a+tu "in,,a persalinan9 usia ,estasi9 e*e+ sampin,
ne,ati*ti$a+ ter$apat per!e$aan si,ni>+an
Kesimpulan
Ni*e$ipin ral persalinan prematur a+ut Se5ara si,ni>+an ti$a+ mempen,aru"i 8memperpan2an,
+e"amilan $an menin,+at+an "asil a+"ir nenatal:
B
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ANTI PROSTAGLANDIN
1@
Tela" lama$i,una+an ral
maupunsupsitria
Terapi
maintenan5e
4 $ata
Insi$ens
li,"i$ramnin$an $u5tal5nstri5tin
tin,,i
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REVIE
Literatur
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*O+O)I-I- M'I%*E%'%CE-(+(*'% /'%*'GO%I-O+-I*O-I%'*O-I'%0
'tosiban /!1# orang0 Placebo /!2# orang0
Inter?al TerapiRe+urensi I persalinanprematur
-- '
Peralinan - min,,u Ti$a+ !er!e$a se5ara statisti+
Nenatal ut5me Ti$a+ !er!e$a se5ara statisti+
Valenuela et alF
Husein et alF
'tosiban /!32
orang0
Placebo /!3"
orang0
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CONTIN%O%S S%
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Ttal B. pasien9 "ana -B an, menerima in*us ter!utalinsu!+utan
Ti$a+ men,e?aluasi terapi $alam pen,,unaan +linis
Ti$a+ men,,una+an +nsultasi *arma+l,is untu+menetap+an $sis !asal ter!utalin an, sesuai untu+ in*us
Ter!utalin pump Jpersalinan prematur
$an +emun,+inan persalinan $ini9memperpan2an, +e"amilan9 Jpera3atan $iNIC%9 J +mpli+asi nenatal9 J !iaa
1.
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KEAMANAN CONTINO%S S%
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MMR 8%S:1'9161@@F@@@8'@@-:1=+ematian
- r, pmpater!utalin $i
ruma"
' ruptureaneurisma ilia+a
1 +e"amilan,an$a
"ip,li+emiaB ter!utalin ral
atau IV
. ter!utalin
su!+utan9 IV9 atauti$a+ $i+eta"ui
8':
1=
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Ke2a$ian +ar$i?as+ularseriuster!utalin 81 anuari
1BB7uli '@@B:
- r, pmpater!utalin $i ruma"
; ter!utalin ral )in2e+si su!+utan
. ter!utalin IV
8-:
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+mpli+asi +ar$i?as+ular $i RS9 t+lisis !eruntun$an6atau $en,an +mr!i$itas
Perr et alFEllit et al
Men,u!a" +ate,ri ter!utalin
C9 !er$asar+an 1=penelitian O3ens memasti+an "asil penelitian Slt+ins
DA
Keputusan DA ti$a+ $i$asar+an penilaian maritas !u+ti
Pr>l +eamanan ter!utalin su!+utan
san,at !ai+ DA "arus mempertim!an,+an ris+!ene>tran,+uman
8.:
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KESIMP%LAN
T+lisis maintena5e mun,+in e*e+ti* untu+ menun$a+ela"iran preterm $iseim!an,+an $en,an e*e+ sampin,
Penelitian le!i" lan2ut "arus $iara"+an pa$a $+umentasipenurunan +ntra+si setela" pem!erian t+lisis
maintenan5e Pmpa in*us Atsi!an 6Ter!utalin su!+utan tampa+na
!erman*aat se!a,ai t+lisis pemeli"araanSan,at$isaan,+an tin$a+an DA men5e,a" pen,,unaante+nl,i ini $i %SA
Pentin, pen2arin,an *a+tr resi+9 mana2emen +asusintensi* an, ter*+us pa$a ANC 9 $ete+si $ini persalinanprematur9 t+lisis a+ut an, e*e+ti*9 J a+ti?itas $i ruma"setela" t+lisis
1B
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TERIMA KASIH