Issue into Issue into PerspectivePerspective

Abel ValdenegroAbel Valdenegro

Cre 101Cre 101

Section 29484Section 29484

What is a blood or marrow What is a blood or marrow transplant?transplant?

• It is a standard treatment for patients It is a standard treatment for patients who have “life-threatening blood, who have “life-threatening blood, immune system or genetic diseases”immune system or genetic diseases”

• It is a transplant that replaces It is a transplant that replaces unhealthy blood cells with healthy unhealthy blood cells with healthy blood cells.blood cells.

• This process takes 3-4 weeks for the This process takes 3-4 weeks for the healthy cells to replace the bad cells.healthy cells to replace the bad cells.

The ProblemThe Problem

• A person who needs bone marrow A person who needs bone marrow transplant needs marrow from a transplant needs marrow from a donor who is close to his or her donor who is close to his or her tissue typetissue type

• It is also more likely the brother and It is also more likely the brother and sister are suitable matches but this sister are suitable matches but this “happens only 25 to 30 percent of “happens only 25 to 30 percent of the time”the time”

The ProblemThe Problem

• Each year about 3,000 patients die Each year about 3,000 patients die every year waiting for bone marrow every year waiting for bone marrow transplant. A number people die also transplant. A number people die also from complications from a partially from complications from a partially matched donor. matched donor.

• ““The problem for cancer patients is that The problem for cancer patients is that only 2% of Americans are on the only 2% of Americans are on the national bone marrow donor registry, national bone marrow donor registry, which makes finding a perfect donor which makes finding a perfect donor match like finding a needle in a match like finding a needle in a haystack”haystack”

Marrow Matches for Marrow Matches for Minorities Minorities

• A static in 2004 shows how many A static in 2004 shows how many minorities are register under the minorities are register under the National Bone Marrow Donor National Bone Marrow Donor Program (NMDP)Program (NMDP)

• In 2004 there is approximately 6.2 In 2004 there is approximately 6.2 million donors registered. million donors registered.

Marrow Matches for Marrow Matches for MinoritiesMinorities

• Whites -- 3,167,307 Whites -- 3,167,307 • Hispanic -- 547,034 Hispanic -- 547,034 • African American -- 490,603 African American -- 490,603 • Asian/Pacific Islander -- 429,177 Asian/Pacific Islander -- 429,177 • Multiple Race/Other -- 160,905 Multiple Race/Other -- 160,905 • American Indian/Alaska Native -- American Indian/Alaska Native --

74,716 74,716 • Decline/Unknown -- 1,415,542 Decline/Unknown -- 1,415,542

How successful are bone How successful are bone marrow transplants?marrow transplants?

• Since 1987 the “NDMP has Since 1987 the “NDMP has facilitated more than 43,000 marrow facilitated more than 43,000 marrow and given patients second chance at and given patients second chance at life”life”

• The chancing of being successful is The chancing of being successful is different for every patient.different for every patient.

Factors that contribute to Factors that contribute to successful transplantssuccessful transplants

• The disease being treated The disease being treated • The stage of the disease The stage of the disease • The patient's age and general health The patient's age and general health • How well the donor's tissue type How well the donor's tissue type

matches the patient matches the patient

The future of bone The future of bone marrowmarrow

• Today bone marrow transplants we Today bone marrow transplants we are learning more and more are learning more and more information about the cells and how information about the cells and how they can also repair tissue damage.they can also repair tissue damage.

• Hopefully in the next 5-10 years we Hopefully in the next 5-10 years we can “develop less cellular therapies can “develop less cellular therapies that will repair and regenerate that will repair and regenerate tissue and organs damage by tissue and organs damage by disease”disease”

ConclusionConclusion

• After my semester of research to After my semester of research to obtain an actual transplant is quite obtain an actual transplant is quite difficult depending the circumstance difficult depending the circumstance of the disease, age and patient.of the disease, age and patient.

• I still standby my decision and go I still standby my decision and go forth with donating bone marrow to forth with donating bone marrow to any patient who is in need. any patient who is in need.

ConclusionConclusion

• After researching it has motivated After researching it has motivated me even more that I become a match me even more that I become a match very soon.very soon.

• I hope to inspire people who have I hope to inspire people who have seen my website or PowerPoint to seen my website or PowerPoint to motivate them to register with motivate them to register with National Bone Marrow Program.National Bone Marrow Program.

Bibliography Bibliography • Kuglar, Mary. "Marrow Matches for Minorities Are Harder to Find - Kuglar, Mary. "Marrow Matches for Minorities Are Harder to Find -

Bone Marrow Transplants." Bone Marrow Transplants." Rare Diseases - Information About Rare Rare Diseases - Information About Rare DiseasesDiseases. ABout.com, 02 Aug. 2009. Web. 01 Dec. 2011. . ABout.com, 02 Aug. 2009. Web. 01 Dec. 2011. <http://rarediseases.about.com/od/rarediseasesb/a/minoritymarrow.ht<http://rarediseases.about.com/od/rarediseasesb/a/minoritymarrow.htm>. m>.

• Kurtzberg, Joanne. "Bone Marrow Transplants." Kurtzberg, Joanne. "Bone Marrow Transplants." DukeHealth.orgDukeHealth.org. . Dukehealth.org, 26 Mar. 2010. Web. 01 Dec. 2011. Dukehealth.org, 26 Mar. 2010. Web. 01 Dec. 2011. <http://www.dukehealth.org/health_library/advice_from_doctors/your_<http://www.dukehealth.org/health_library/advice_from_doctors/your_childs_health/bonemarrowtransplants>. childs_health/bonemarrowtransplants>.

• Majumder, Kumud. "Let's Compensate Bone Marrow Donors - Majumder, Kumud. "Let's Compensate Bone Marrow Donors - USATODAY.com." USATODAY.com." News, Travel, Weather, Entertainment, Sports, News, Travel, Weather, Entertainment, Sports, Technology, U.S. & World - USATODAY.comTechnology, U.S. & World - USATODAY.com. USA Today, 02 Feb. . USA Today, 02 Feb. 2011. Web. 01 Dec. 2011. 2011. Web. 01 Dec. 2011. <http://www.usatoday.com/news/opinion/forum/2011-02-09-<http://www.usatoday.com/news/opinion/forum/2011-02-09-majumder11_st_N.htm>. majumder11_st_N.htm>.

• "Patient FAQs." "Patient FAQs." Be The Match Marrow RegistryBe The Match Marrow Registry. National Bone . National Bone Marrow Program. Web. 01 Dec. 2011. Marrow Program. Web. 01 Dec. 2011. <http://marrow.org/Patient/Support_and_Resources/Patient_FAQs.asp<http://marrow.org/Patient/Support_and_Resources/Patient_FAQs.aspx> x>